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Erin M. Janssen, Ph.D. - Publications

Affiliations: 
Duke University, Durham, NC 
Area:
Condensed matter theory
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wobma H, Janssen E. Expanding IPEX: Inborn Errors of Regulatory T Cells. Rheumatic Diseases Clinics of North America. 49: 825-840. PMID 37821198 DOI: 10.1016/j.rdc.2023.06.009  0.332
2023 Julé AM, Lam KP, Taylor M, Hoyt KJ, Wei K, Gutierrez-Arcelus M, Case SM, Chandler M, Chang MH, Cohen EM, Dedeoglu F, Halyabar O, Hausmann J, Hazen MM, Janssen E, et al. Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. Frontiers in Immunology. 13: 1068399. PMID 36685593 DOI: 10.3389/fimmu.2022.1068399  0.454
2022 Janssen E, Alosaimi MF, Alazami AM, Alsuliman A, Alaiya A, Al-Saud B, Al-Mousa H, Al-Zaid TJ, Smith E, Platt CD, Alruwaili H, Albanyan S, Al-Mayouf SM, Geha RS. A homozygous truncating mutation of FGL2 is associated with immune dysregulation. The Journal of Allergy and Clinical Immunology. PMID 36243222 DOI: 10.1016/j.jaci.2022.10.006  0.353
2022 Janssen E, Peters Z, Alosaimi MF, Smith E, Milin E, Stafstrom K, Wallace JG, Platt CD, Chou J, El Ansari YS, Al Farsi T, Ameziane N, Al-Ali R, Calvo M, Rocha ME, et al. Immune dysregulation caused by homozygous mutations in CBLB. The Journal of Clinical Investigation. PMID 36006710 DOI: 10.1172/JCI154487  0.415
2022 Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, et al. Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nature Immunology. PMID 35332329 DOI: 10.1038/s41590-022-01180-8  0.359
2021 Julé AM, Hoyt KJ, Wei K, Gutierrez-Arcelus M, Taylor ML, Ng J, Lederer JA, Case SM, Chang MH, Cohen EM, Dedeoglu F, Hazen MM, Hausmann JS, Halyabar O, Janssen E, et al. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Jci Insight. PMID 34403374 DOI: 10.1172/jci.insight.149185  0.317
2020 Wilkie H, Janssen E, Leyva-Castillo JM, Geha RS. DOCK8 expression in Treg cells maintains their stability and limits contact hypersensitivity. The Journal of Investigative Dermatology. PMID 33171169 DOI: 10.1016/j.jid.2020.09.027  0.318
2020 Janssen E, Tohme M, Butts J, Giguere SS, Sage PT, Velázquez FE, Kam C, Milin E, Das M, Sobh A, Al-Tamemi S, Luscinskas FW, Batista F, Geha RS. DOCK8 is essential for LFA-1 dependent positioning of T follicular helper cells in germinal centers. Jci Insight. PMID 32573493 DOI: 10.1172/Jci.Insight.134508  0.537
2020 Henderson LA, Hoyt KJ, Lee PY, Rao DA, Jonsson AH, Nguyen JP, Rutherford K, Julé AM, Charbonnier LM, Case S, Chang MH, Cohen EM, Dedeoglu F, Fuhlbrigge RC, Halyabar O, ... ... Janssen E, et al. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. Jci Insight. 5. PMID 32213704 DOI: 10.1172/Jci.Insight.132508  0.385
2020 Kumari S, Mak M, Poh YC, Tohme M, Watson N, Melo M, Janssen E, Dustin M, Geha R, Irvine DJ. Cytoskeletal tension actively sustains the migratory T-cell synaptic contact. The Embo Journal. e102783. PMID 31894880 DOI: 10.15252/Embj.2019102783  0.455
2019 Verheijen J, Wong SY, Rowe JH, Raymond K, Stoddard J, Delmonte OM, Bosticardo M, Dobbs K, Niemela J, Calzoni E, Pai SY, Choi U, Yamazaki Y, Comeau AM, Janssen E, et al. Defining a new immune deficiency syndrome: MAN2B2-CDG. The Journal of Allergy and Clinical Immunology. PMID 31775018 DOI: 10.1016/J.Jaci.2019.11.016  0.328
2019 Janssen E, Geha RS. Primary immunodeficiencies caused by mutations in actin regulatory proteins. Immunological Reviews. 287: 121-134. PMID 30565251 DOI: 10.1111/Imr.12716  0.382
2018 Biswas A, Shouval DS, Griffith A, Goettel JA, Field M, Kang YH, Konnikova L, Janssen E, Redhu NS, Thrasher AJ, Chatila T, Kuchroo VK, Geha RS, Notarangelo LD, Pai SY, et al. WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. Nature Communications. 9: 1779. PMID 29725003 DOI: 10.1038/S41467-018-03670-6  0.323
2017 Janssen E, Kumari S, Tohme M, Ullas S, Barrera V, Tas JM, Castillo-Rama M, Bronson RT, Usmani SM, Irvine DJ, Mempel TR, Geha RS. DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs. Jci Insight. 2. PMID 28978806 DOI: 10.1172/Jci.Insight.94298  0.429
2016 Massaad MJ, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, Glauzy S, Olson BG, Morbach H, Ohsumi TK, Schmitz K, Kyriacos M, Kane J, Torisu K, Nakabeppu Y, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. The Journal of Clinical Investigation. PMID 27760045 DOI: 10.1172/Jci85647  0.517
2016 Jabara HH, Lee JJ, Janssen E, Ullas S, Liadaki K, Garibyan L, Benson H, Sannikova T, Bram R, Hammarstrom L, Cruz AC, Siegel R, Manis J, Malley R, Geha RS. Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice. The Journal of Allergy and Clinical Immunology. PMID 27609654 DOI: 10.1016/J.Jaci.2016.07.028  0.387
2016 Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. The Journal of Clinical Investigation. PMID 27599296 DOI: 10.1172/Jci85774  0.479
2016 Henderson LA, Volpi S, Frugoni F, Janssen E, Kim S, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Son MB, Mathieu R, Zurakowski D, Yu N, Lebedeva T, Fuhlbrigge RC, et al. Next Generation Sequencing Reveals Restriction and Clonotypic Expansion of Regulatory T Cells in Juvenile Idiopathic Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26815131 DOI: 10.1002/Art.39606  0.464
2015 Charbonnier LM, Janssen E, Chou J, Ohsumi TK, Keles S, Hsu JT, Massaad MJ, Garcia-Lloret M, Hanna-Wakim R, Dbaibo G, Alangari AA, Alsultan A, Al-Zahrani D, Geha RS, Chatila TA. Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA. The Journal of Allergy and Clinical Immunology. 135: 217-27. PMID 25468195 DOI: 10.1016/J.Jaci.2014.10.019  0.527
2015 Charbonnier LM, Janssen E, Chou J, Ohsumi TK, Keles S, Hsu JT, Massaad MJ, Garcia-Lloret M, Hanna-Wakim R, Dbaibo G, Alangari AA, Alsultan A, Al-Zahrani D, Geha RS, Chatila TA. Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA Journal of Allergy and Clinical Immunology. 135: 217-227. DOI: 10.1016/j.jaci.2014.10.019  0.301
2014 Janssen E, Morbach H, Ullas S, Bannock JM, Massad C, Menard L, Barlan I, Lefranc G, Su H, Dasouki M, Al-Herz W, Keles S, Chatila T, Geha RS, Meffre E. Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells. The Journal of Allergy and Clinical Immunology. 134: 1365-74. PMID 25218284 DOI: 10.1016/J.Jaci.2014.07.042  0.485
2014 Janssen E, Ozcan E, Liadaki K, Jabara HH, Manis J, Ullas S, Akira S, Fitzgerald KA, Golenbock DT, Geha RS. TRIF signaling is essential for TLR4-driven IgE class switching. Journal of Immunology (Baltimore, Md. : 1950). 192: 2651-8. PMID 24532577 DOI: 10.4049/Jimmunol.1300909  0.384
2014 Janssen E, Tsitsikov E, Al-Herz W, Lefranc G, Megarbane A, Dasouki M, Bonilla FA, Chatila T, Schneider L, Geha RS. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis. Clinical Immunology (Orlando, Fla.). 150: 220-4. PMID 24440647 DOI: 10.1016/J.Clim.2013.12.006  0.303
2014 Henderson LA, Volpi S, Frugoni F, Kim S, Janssen E, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Mathieu R, Fuhlbrigge RC, Lee YN, Nigrovic PA, Notarangelo LD. A119: Deep Sequencing Analysis of the T Regulatory and T Effector Repertoire in Juvenile Idiopathic Arthritis Arthritis & Rheumatology. 66: S156-S156. DOI: 10.1002/Art.38540  0.394
2013 Uzel G, Sampaio EP, Lawrence MG, Hsu AP, Hackett M, Dorsey MJ, Noel RJ, Verbsky JW, Freeman AF, Janssen E, Bonilla FA, Pechacek J, Chandrasekaran P, Browne SK, Agharahimi A, et al. Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. The Journal of Allergy and Clinical Immunology. 131: 1611-23. PMID 23534974 DOI: 10.1016/J.Jaci.2012.11.054  0.328
2013 Benedict CA, Arens R, Loewendorf A, Janssen EM. Modulation of T-Cell mediated immunity by cytomegalovirus Control of Innate and Adaptive Immune Responses During Infectious Diseases. 121-139. DOI: 10.1007/978-1-4614-0484-2_7  0.332
2012 Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, et al. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nature Immunology. 13: 612-20. PMID 22581261 DOI: 10.1038/Ni.2305  0.483
2012 Wolkers MC, Gerlach C, Arens R, Janssen EM, Fitzgerald P, Schumacher TN, Medema JP, Green DR, Schoenberger SP. Nab2 regulates secondary CD8+ T-cell responses through control of TRAIL expression. Blood. 119: 798-804. PMID 22128144 DOI: 10.1182/Blood-2011-08-373910  0.315
2011 Katz JD, Janssen EM. Breaking T cell tolerance to beta cell antigens by merocytic dendritic cells. Cellular and Molecular Life Sciences : Cmls. 68: 2873-83. PMID 21626409 DOI: 10.1007/s00018-011-0730-6  0.361
2010 Katz JD, Ondr JK, Opoka RJ, Garcia Z, Janssen EM. Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes. Journal of Immunology (Baltimore, Md. : 1950). 185: 1999-2003. PMID 20644171 DOI: 10.4049/jimmunol.1001398  0.329
2010 Janssen EM, Lemmens EE, Gour N, Reboulet RA, Green DR, Schoenberger SP, Pinkoski MJ. Distinct roles of cytolytic effector molecules for antigen-restricted killing by CTL in vivo. Immunology and Cell Biology. 88: 761-5. PMID 20309009 DOI: 10.1038/Icb.2010.37  0.316
2008 Bensinger SJ, Bradley MN, Joseph SB, Zelcer N, Janssen EM, Hausner MA, Shih R, Parks JS, Edwards PA, Jamieson BD, Tontonoz P. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell. 134: 97-111. PMID 18614014 DOI: 10.1016/J.Cell.2008.04.052  0.304
2005 Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, Griffith TS, Green DR, Schoenberger SP. CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature. 434: 88-93. PMID 15744305 DOI: 10.1038/Nature03337  0.322
2004 Janssen E, Zhu M, Craven B, Zhang W. Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-gamma1 binding. Journal of Immunology (Baltimore, Md. : 1950). 172: 6810-9. PMID 15153499 DOI: 10.4049/Jimmunol.172.11.6810  0.588
2004 Koonpaew S, Janssen E, Zhu M, Zhang W. The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB. The Journal of Biological Chemistry. 279: 11229-35. PMID 14722116 DOI: 10.1074/Jbc.M311394200  0.666
2004 Janssen E, Zhang W. Adaptor proteins in lymphocyte activation. Current Opinion in Immunology. 15: 269-76. PMID 12787751 DOI: 10.1016/S0952-7915(03)00044-X  0.363
2003 Janssen E, Zhu M, Zhang W, Koonpaew S, Zhang W. LAB: a new membrane-associated adaptor molecule in B cell activation. Nature Immunology. 4: 117-23. PMID 12514734 DOI: 10.1038/Ni882  0.666
2003 Zhu M, Janssen E, Zhang W. Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development. Journal of Immunology (Baltimore, Md. : 1950). 170: 325-33. PMID 12496416 DOI: 10.4049/Jimmunol.170.1.325  0.581
2002 Zhu M, Janssen E, Leung K, Zhang W. Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. The Journal of Biological Chemistry. 277: 46151-8. PMID 12359715 DOI: 10.1074/Jbc.M208946200  0.573
2002 Cao Y, Janssen EM, Duncan AW, Altman A, Billadeau DD, Abraham RT. Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line. The Embo Journal. 21: 4809-19. PMID 12234921 DOI: 10.1093/Emboj/Cdf499  0.523
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