Daniel M. Bowles, Ph.D. - Publications

University of Kentucky, Lexington, KY 
organic chemistry, materials chemistry

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Blackburn A, Bowles DM, Curran TT, Kim H. Air oxidation of N-cyclopropylanilines Synthetic Communications. 42: 1855-1863. DOI: 10.1080/00397911.2010.545166  0.92
2011 Pfefferkorn JA, Litchfield J, Hutchings R, Cheng XM, Larsen SD, Auerbach B, Bush MR, Lee C, Erasga N, Bowles DM, Boyles DC, Lu G, Sekerke C, Askew V, Hanselman JC, et al. Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution. Bioorganic & Medicinal Chemistry Letters. 21: 2725-31. PMID 21183342 DOI: 10.1016/J.Bmcl.2010.11.103  0.92
2011 Huang Q, Richardson PF, Sach NW, Zhu J, Liu KKC, Smith GL, Bowles DM. Development of scalable syntheses of selective PI3K inhibitors Organic Process Research and Development. 15: 556-564. DOI: 10.1021/op100286g  0.92
2011 Bowles DM, Boyles DC, Choi C, Pfefferkorn JA, Schuyler S, Hessler EJ. Development of an early enabling synthesis for PF-03052334-02: A novel hepatoselective HMG-CoA reductase inhibitor Organic Process Research and Development. 15: 148-157. DOI: 10.1021/Op100268E  0.92
2011 Boos C, Bowles DM, Cai C, Casimiro-Garcia A, Chen X, Hulford CA, Jennings SM, Jason Kiser E, Piotrowski DW, Sammons M, Wade RA. Synthesis and cross coupling of a highly substituted 2-pyridylboronate: Application to the large scale synthesis of a mineralocorticoid antagonist Tetrahedron Letters. 52: 7025-7029. DOI: 10.1016/J.Tetlet.2011.10.052  0.92
2011 Chen R, Bowles D, Antosz F, Xiang Y, Li S, Barrila M, Coutant M. Practical approaches in applying Process Analytical Technology (PAT) tools to early Active Pharmaceutical Ingredient (API) development Pharmaceutical Outsourcing. 12: 28-33.  0.92
2009 Magano J, Bowles D, Conway B, Nanninga TN, Winkle DD. Diastereoselective, large-scale synthesis of β-amino acids via asymmetric aza-Michael addition as α2δ ligands for the treatment of generalized anxiety disorder and insomnia Tetrahedron Letters. 50: 6325-6328. DOI: 10.1016/j.tetlet.2009.08.119  0.92
2009 Magano J, Conway B, Bowles D, Nelson J, Nanninga TN, Winkle DD, Wu H, Chen MH. Diastereoselective, large scale synthesis of β-amino acids via asymmetric enamide hydrogenation as α2δ ligands for the treatment of generalized anxiety disorder and insomnia Tetrahedron Letters. 50: 6329-6331. DOI: 10.1016/j.tetlet.2009.08.111  0.92
2009 Chandrasekaran P, Donahue JP, Bowles DM, Ragan JA. Synthesis of 4,5-Dimethyl-1,3-dithiol-2-one Organic Syntheses. 86: 333-343. DOI: 10.1002/0471264229.Os086.32  0.92
2008 Bowles DM, Bolton GL, Boyles DC, Curran TT, Hutchings RH, Larsen SD, Miller JM, Park WKC, Ritsema KG, Schineman DC, Tamm M. Preparation of a HMG-CoA reductase inhibitor via an optimized imidazole-forming condensation reaction Organic Process Research and Development. 12: 1183-1187. DOI: 10.1021/op800092e  0.92
2007 Pfefferkorn JA, Bowles DM, Kissel W, Boyles DC, Choi C, Larsen SD, Song Y, Sun KL, Miller SR, Trivedi BK. Development of a practical synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors Tetrahedron. 63: 8124-8134. DOI: 10.1016/J.Tet.2007.06.005  0.92
2001 Bowles DM, Palmer GJ, Landis CA, Scott JL, Anthony JE. The Bergman reaction as a synthetic tool: Advantages and restrictions Tetrahedron. 57: 3753-3760. DOI: 10.1016/S0040-4020(01)00247-2  0.92
2000 Bowles DM, Anthony JE. A reiterative approach to 2,3-disubstituted naphthalenes and anthracenes Organic Letters. 2: 85-7. PMID 10814252 DOI: 10.1021/Ol991254W  0.92
2000 Chow SY, Palmer GJ, Bowles DM, Anthony JE. Perylene synthesis by the parallel cycloaromatization of adjacent enediynes Organic Letters. 2: 961-3. PMID 10768197 DOI: 10.1021/Ol005615F  0.92
2000 Palmer GJ, Bowles DM, Landis C, Anthony JE. Cycloaromatization approach to planar and cylindrical carbon oligomers Carbon. 38: 1671-1674. DOI: 10.1016/S0008-6223(00)00054-3  0.92
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