Cyrus Michael Ghajar - Publications

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, ... Ghajar CM, et al. Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy. Nature Cell Biology. PMID 30664790 DOI: 10.1038/s41556-018-0267-0  0.32
2018 Goddard ET, Bozic I, Riddell SR, Ghajar CM. Dormant tumour cells, their niches and the influence of immunity. Nature Cell Biology. 20: 1240-1249. PMID 30361702 DOI: 10.1038/s41556-018-0214-0  0.32
2015 Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, ... ... Ghajar CM, et al. Tumour exosome integrins determine organotropic metastasis. Nature. PMID 26524530 DOI: 10.1038/nature15756  1
2015 Ghajar CM. Metastasis prevention by targeting the dormant niche. Nature Reviews. Cancer. 15: 238-47. PMID 25801619 DOI: 10.1038/nrc3910  1
2014 Ghajar CM. A stiffness-mediated oncogenic hammer. Science Translational Medicine. 6: 237fs21. PMID 24848253 DOI: 10.1126/scitranslmed.3009154  1
2014 Weigelt B, Ghajar CM, Bissell MJ. The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer. Advanced Drug Delivery Reviews. 69: 42-51. PMID 24412474 DOI: 10.1016/j.addr.2014.01.001  1
2014 Ghajar CM. A fine line between healing and fibrosis Science Translational Medicine. 6. DOI: 10.1126/scitranslmed.3008648  1
2014 Ghajar CM. Hold the sugar Science Translational Medicine. 6. DOI: 10.1126/scitranslmed.3008245  1
2014 Ghajar CM, Correia AL, Bissell MJ. The Role of the Microenvironment in Tumor Initiation, Progression, and Metastasis The Molecular Basis of Cancer: Fourth Edition. 239-256.e5. DOI: 10.1016/B978-1-4557-4066-6.00016-0  1
2013 Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DY, Chen EI, Lyden D, Bissell MJ. The perivascular niche regulates breast tumour dormancy. Nature Cell Biology. 15: 807-17. PMID 23728425 DOI: 10.1038/ncb2767  1
2013 Ghosh S, Ashcraft K, Jahid MJ, April C, Ghajar CM, Ruan J, Wang H, Foster M, Hughes DC, Ramirez AG, Huang T, Fan JB, Hu Y, Li R. Regulation of adipose oestrogen output by mechanical stress. Nature Communications. 4: 1821. PMID 23652009 DOI: 10.1038/ncomms2794  1
2013 Mori H, Lo AT, Inman JL, Alcaraz J, Ghajar CM, Mott JD, Nelson CM, Chen CS, Zhang H, Bascom JL, Seiki M, Bissell MJ. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (Cambridge, England). 140: 343-52. PMID 23250208 DOI: 10.1242/dev.084236  1
2013 Ghajar CM. Cancer: My house is not your house | Cancer: Mi casa no es su casa Science Translational Medicine. 5. DOI: 10.1126/scitranslmed.3007984  1
2013 Ghajar CM. Creating refuge Science Translational Medicine. 5. DOI: 10.1126/scitranslmed.3007714  1
2013 Ghajar CM. Lucky VII? A dual role for collagen in wound healing Science Translational Medicine. 5. DOI: 10.1126/scitranslmed.3006925  1
2013 Ghajar CM. Keeping metastasis at bay Science Translational Medicine. 5. DOI: 10.1126/scitranslmed.3006621  1
2013 Ghajar CM. A one-man show: Glioblastoma constructs its own niche Science Translational Medicine. 5. DOI: 10.1126/scitranslmed.3006348  1
2013 Ghajar CM. Perivascular niche: A jagged edge to cancer chemoresistance Science Translational Medicine. 5. DOI: 10.1126/scitranslmed.3006076  1
2012 Peinado H, Ale?kovi? M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature Medicine. 18: 883-91. PMID 22635005 DOI: 10.1038/nm.2753  1
2012 Ghajar CM. On leukocytes in mammary development and cancer. Cold Spring Harbor Perspectives in Biology. 4. PMID 22550234 DOI: 10.1101/cshperspect.a013276  1
2012 Mori H, Borowsky AD, Bhat R, Ghajar CM, Seiki M, Bissell MJ. Laser scanning-based tissue autofluorescence/fluorescence imaging (LS-TAFI), a new technique for analysis of microanatomy in whole-mount tissues. The American Journal of Pathology. 180: 2249-56. PMID 22542846 DOI: 10.1016/j.ajpath.2012.02.032  1
2012 Bissell MJ, Ghajar CM, Lee LP. From single cells to biology. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 357-9. PMID 22436976 DOI: 10.1039/c2ib90010f  1
2011 Furuta S, Ghajar CM, Bissell MJ. Caveolin-1: would-be Achilles' heel of tumor microenvironment? Cell Cycle (Georgetown, Tex.). 10: 3431. PMID 22030625 DOI: 10.4161/cc.10.20.17648  1
2011 Alcaraz J, Mori H, Ghajar CM, Brownfield D, Galgoczy R, Bissell MJ. Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 1153-66. PMID 21993836 DOI: 10.1039/c1ib00073j  1
2011 Matei I, Ghajar CM, Lyden D. A TeNaCious foundation for the metastatic niche. Cancer Cell. 20: 139-41. PMID 21840480 DOI: 10.1016/j.ccr.2011.08.004  1
2010 Carrion B, Huang CP, Ghajar CM, Kachgal S, Kniazeva E, Jeon NL, Putnam AJ. Recreating the perivascular niche ex vivo using a microfluidic approach. Biotechnology and Bioengineering. 107: 1020-8. PMID 20672286 DOI: 10.1002/bit.22891  1
2010 Ghajar CM, Bissell MJ. Tumor engineering: the other face of tissue engineering. Tissue Engineering. Part A. 16: 2153-6. PMID 20214448 DOI: 10.1089/ten.TEA.2010.0135  1
2010 Ghajar CM, Kachgal S, Kniazeva E, Mori H, Costes SV, George SC, Putnam AJ. Mesenchymal cells stimulate capillary morphogenesis via distinct proteolytic mechanisms. Experimental Cell Research. 316: 813-25. PMID 20067788 DOI: 10.1016/j.yexcr.2010.01.013  1
2009 Chen A, Cuevas I, Kenny PA, Miyake H, Mace K, Ghajar C, Boudreau A, Bissell MJ, Bissell M, Boudreau N. Endothelial cell migration and vascular endothelial growth factor expression are the result of loss of breast tissue polarity. Cancer Research. 69: 6721-9. PMID 19654314 DOI: 10.1158/0008-5472.CAN-08-4069  1
2009 Ghajar CM, Meier R, Bissell MJ. Quis custodiet ipsos custodies: who watches the watchmen? The American Journal of Pathology. 174: 1996-9. PMID 19465642 DOI: 10.2353/ajpath.2009.090363  1
2009 Chen X, Aledia AS, Ghajar CM, Griffith CK, Putnam AJ, Hughes CC, George SC. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature. Tissue Engineering. Part A. 15: 1363-71. PMID 18976155 DOI: 10.1089/ten.tea.2008.0314  1
2008 Ghajar CM, Bissell MJ. Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging. Histochemistry and Cell Biology. 130: 1105-18. PMID 19009245 DOI: 10.1007/s00418-008-0537-1  1
2008 Ghajar CM, George SC, Putnam AJ. Matrix metalloproteinase control of capillary morphogenesis. Critical Reviews in Eukaryotic Gene Expression. 18: 251-78. PMID 18540825  1
2008 Peyton SR, Kim PD, Ghajar CM, Seliktar D, Putnam AJ. The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system. Biomaterials. 29: 2597-607. PMID 18342366 DOI: 10.1016/j.biomaterials.2008.02.005  1
2008 Ghajar CM, Chen X, Harris JW, Suresh V, Hughes CC, Jeon NL, Putnam AJ, George SC. The effect of matrix density on the regulation of 3-D capillary morphogenesis. Biophysical Journal. 94: 1930-41. PMID 17993494 DOI: 10.1529/biophysj.107.120774  1
2007 Peyton SR, Ghajar CM, Khatiwala CB, Putnam AJ. The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function. Cell Biochemistry and Biophysics. 47: 300-20. PMID 17652777 DOI: 10.1007/s12013-007-0004-y  1
2007 Ghajar CM, Suresh V, Peyton SR, Raub CB, Meyskens FL, George SC, Putnam AJ. A novel three-dimensional model to quantify metastatic melanoma invasion. Molecular Cancer Therapeutics. 6: 552-61. PMID 17267658 DOI: 10.1158/1535-7163.MCT-06-0593  1
2006 Ghajar CM, Blevins KS, Hughes CC, George SC, Putnam AJ. Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation. Tissue Engineering. 12: 2875-88. PMID 17518656 DOI: 10.1089/ten.2006.12.2875  1
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