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Nathaniel D. Huebsch - Publications

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
Area:
Cellular biology; Biomedical engineering; Biophysics
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Huebsch N, Charrez B, Neiman G, Siemons B, Boggess SC, Wall S, Charwat V, Jæger KH, Cleres D, Telle Å, Lee-Montiel FT, Jeffreys NC, Deveshwar N, Edwards AG, Serrano J, et al. Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips. Nature Biomedical Engineering. 6: 372-388. PMID 35478228 DOI: 10.1038/s41551-022-00884-4  0.349
2019 Huebsch N. Translational mechanobiology: Designing synthetic hydrogel matrices for improved in vitro models and cell-based therapies. Acta Biomaterialia. 94: 97-111. PMID 31129361 DOI: 10.1016/j.actbio.2019.05.055  0.353
2019 Loskill P, Huebsch N. Engineering Tissues from Induced Pluripotent Stem Cells. Tissue Engineering. Part A. 25: 707-710. PMID 31030627 DOI: 10.1089/ten.TEA.2019.0118  0.356
2018 Ma Z, Huebsch N, Koo S, Mandegar MA, Siemons B, Boggess S, Conklin BR, Grigoropoulos CP, Healy KE. Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. Nature Biomedical Engineering. 2: 955-967. PMID 31015724 DOI: 10.1038/S41551-018-0280-4  0.356
2018 Tveito A, Jæger KH, Huebsch N, Charrez B, Edwards AG, Wall S, Healy KE. Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems. Scientific Reports. 8: 17626. PMID 30514966 DOI: 10.1038/S41598-018-35858-7  0.387
2017 Cipitria A, Boettcher K, Schoenhals S, Garske DS, Schmidt-Bleek K, Ellinghaus A, Dienelt A, Peters A, Mehta M, Madl CM, Huebsch N, Mooney DJ, Duda GN. In-situ tissue regeneration through SDF-1α driven cell recruitment and stiffness-mediated bone regeneration in a critical-sized segmental femoral defect. Acta Biomaterialia. PMID 28739546 DOI: 10.1016/J.Actbio.2017.07.032  0.572
2016 Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, B Fox C, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, et al. Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Scientific Reports. 6: 24726. PMID 27095412 DOI: 10.1038/Srep24726  0.35
2016 Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, et al. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. PMID 26971820 DOI: 10.1016/J.Stem.2016.01.022  0.315
2015 Chaudhuri O, Gu L, Klumpers D, Darnell M, Bencherif SA, Weaver JC, Huebsch N, Lee HP, Lippens E, Duda GN, Mooney DJ. Hydrogels with tunable stress relaxation regulate stem cell fate and activity. Nature Materials. PMID 26618884 DOI: 10.1038/Nmat4489  0.689
2015 Huebsch N, Lippens E, Lee K, Mehta M, Koshy ST, Darnell MC, Desai RM, Madl CM, Xu M, Zhao X, Chaudhuri O, Verbeke C, Kim WS, Alim K, Mammoto A, et al. Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation. Nature Materials. PMID 26366848 DOI: 10.1038/Nmat4407  0.752
2015 Ma Z, Wang J, Loskill P, Huebsch N, Koo S, Svedlund FL, Marks NC, Hua EW, Grigoropoulos CP, Conklin BR, Healy KE. Self-organizing human cardiac microchambers mediated by geometric confinement. Nature Communications. 6: 7413. PMID 26172574 DOI: 10.1038/Ncomms8413  0.371
2015 Mathur A, Loskill P, Shao K, Huebsch N, Hong S, Marcus SG, Marks N, Mandegar M, Conklin BR, Lee LP, Healy KE. Human iPSC-based cardiac microphysiological system for drug screening applications. Scientific Reports. 5: 8883. PMID 25748532 DOI: 10.1038/Srep08883  0.338
2015 Chaudhuri O, Gu L, Darnell M, Klumpers D, Bencherif SA, Weaver JC, Huebsch N, Mooney DJ. Substrate stress relaxation regulates cell spreading. Nature Communications. 6: 6364. PMID 25695512 DOI: 10.1038/Ncomms7365  0.639
2015 Huebsch N, Loskill P, Mandegar MA, Marks NC, Sheehan AS, Ma Z, Mathur A, Nguyen TN, Yoo JC, Judge LM, Spencer CI, Chukka AC, Russell CR, So PL, Conklin BR, et al. Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales. Tissue Engineering. Part C, Methods. 21: 467-79. PMID 25333967 DOI: 10.1089/Ten.Tec.2014.0283  0.398
2014 Huebsch N, Kearney CJ, Zhao X, Kim J, Cezar CA, Suo Z, Mooney DJ. Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. 111: 9762-7. PMID 24961369 DOI: 10.1073/Pnas.1405469111  0.616
2014 Ma Z, Koo S, Finnegan MA, Loskill P, Huebsch N, Marks NC, Conklin BR, Grigoropoulos CP, Healy KE. Three-dimensional filamentous human diseased cardiac tissue model. Biomaterials. 35: 1367-77. PMID 24268663 DOI: 10.1016/J.Biomaterials.2013.10.052  0.342
2014 Uhrig BA, Clements IP, Boerckel JD, Huebsch N, Bellamkonda RV, Guldberg RE. Characterization of a composite injury model of severe lower limb bone and nerve trauma. Journal of Tissue Engineering and Regenerative Medicine. 8: 432-41. PMID 22689452 DOI: 10.1002/Term.1537  0.311
2013 Uhrig BA, Boerckel JD, Willett NJ, Li MT, Huebsch N, Guldberg RE. Recovery from hind limb ischemia enhances rhBMP-2-mediated segmental bone defect repair in a rat composite injury model. Bone. 55: 410-7. PMID 23664918 DOI: 10.1016/J.Bone.2013.04.027  0.318
2012 Kim WS, Mooney DJ, Arany PR, Lee K, Huebsch N, Kim J. Adipose tissue engineering using injectable, oxidized alginate hydrogels. Tissue Engineering. Part A. 18: 737-43. PMID 22011105 DOI: 10.1089/Ten.Tea.2011.0250  0.718
2011 Boerckel JD, Uhrig BA, Willett NJ, Huebsch N, Guldberg RE. Mechanical regulation of vascular growth and tissue regeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: E674-80. PMID 21876139 DOI: 10.1073/Pnas.1107019108  0.338
2011 Kolambkar YM, Boerckel JD, Dupont KM, Bajin M, Huebsch N, Mooney DJ, Hutmacher DW, Guldberg RE. Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects. Bone. 49: 485-92. PMID 21621027 DOI: 10.1016/J.Bone.2011.05.010  0.486
2011 Bencherif SA, Guillemot F, Huebsch N, Edwards DA, Mooney DJ. [Cell-traction mediated configuration of the cell/extracellular-matrix interface plays a key role in stem cell fate]. MéDecine Sciences : M/S. 27: 19-21. PMID 21299954 DOI: 10.1051/Medsci/201127119  0.436
2011 Zhao X, Kim J, Cezar CA, Huebsch N, Lee K, Bouhadir K, Mooney DJ. Active scaffolds for on-demand drug and cell delivery. Proceedings of the National Academy of Sciences of the United States of America. 108: 67-72. PMID 21149682 DOI: 10.1073/pnas.1007862108  0.674
2011 Kolambkar YM, Dupont KM, Boerckel JD, Huebsch N, Mooney DJ, Hutmacher DW, Guldberg RE. An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. Biomaterials. 32: 65-74. PMID 20864165 DOI: 10.1016/J.Biomaterials.2010.08.074  0.503
2011 Huebsch N, Mooney DJ. A role for integrin-ECM Bonds as mechanotransducers that modulate adult stem cell fate Mechanobiology of Cell-Cell and Cell-Matrix Interactions. 23-46. DOI: 10.1007/978-1-4419-8083-0_3  0.475
2010 Zhao X, Huebsch N, Mooney DJ, Suo Z. Stress-relaxation behavior in gels with ionic and covalent crosslinks. Journal of Applied Physics. 107: 63509. PMID 21464912 DOI: 10.1063/1.3343265  0.428
2010 Huebsch N, Arany PR, Mao AS, Shvartsman D, Ali OA, Bencherif SA, Rivera-Feliciano J, Mooney DJ. Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. Nature Materials. 9: 518-26. PMID 20418863 DOI: 10.1038/Nmat2732  0.721
2010 Chueh BH, Zheng Y, Torisawa YS, Hsiao AY, Ge C, Hsiong S, Huebsch N, Franceschi R, Mooney DJ, Takayama S. Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device. Biomedical Microdevices. 12: 145-51. PMID 19830565 DOI: 10.1007/S10544-009-9369-6  0.715
2010 Kolambkar YM, Boerckel JD, Dupont KM, Bajin M, Huebsch N, Mooney DJ, Bellamkonda RV, Garcia AJ, Hutmacher DW, Guldberg RE. Electrospun nanofibers meshes for the repair of bone defects American Association of Textile Chemists and Colorists International Conference 2010. 357-361.  0.383
2009 Huebsch N, Mooney DJ. Inspiration and application in the evolution of biomaterials. Nature. 462: 426-32. PMID 19940912 DOI: 10.1038/Nature08601  0.434
2009 Ali OA, Huebsch N, Cao L, Dranoff G, Mooney DJ. Infection-mimicking materials to program dendritic cells in situ. Nature Materials. 8: 151-8. PMID 19136947 DOI: 10.1038/Nmat2357  0.489
2009 Hsiong SX, Boontheekul T, Huebsch N, Mooney DJ. Cyclic arginine-glycine-aspartate peptides enhance three-dimensional stem cell osteogenic differentiation. Tissue Engineering. Part A. 15: 263-72. PMID 18783323 DOI: 10.1089/Ten.Tea.2007.0411  0.689
2008 Hsiong SX, Huebsch N, Fischbach C, Kong HJ, Mooney DJ. Integrin-adhesion ligand bond formation of preosteoblasts and stem cells in three-dimensional RGD presenting matrices. Biomacromolecules. 9: 1843-51. PMID 18540674 DOI: 10.1021/Bm8000606  0.761
2007 Hyun JK, Chan JK, Huebsch N, Weitz D, Mooney DJ. Noninvasive probing of the spatial organization of polymer chains in hydrogels using fluorescence resonance energy transfer (FRET) Journal of the American Chemical Society. 129: 4518-4519. PMID 17381090 DOI: 10.1021/Ja0690058  0.415
2007 Huebsch ND, Mooney DJ. Fluorescent resonance energy transfer: A tool for probing molecular cell-biomaterial interactions in three dimensions. Biomaterials. 28: 2424-37. PMID 17270268 DOI: 10.1016/J.Biomaterials.2007.01.023  0.558
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