Robert J. Linhardt - Publications

Affiliations: 
1982-2003 Medicinal and Natural Products Chemistry University of Iowa, Iowa City, IA 
 2003- Biocatalysis and Metabolic Engineering Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Heparin
Website:
http://www-heparin.rpi.edu/main/people/view/1

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Year Citation  Score
2019 Zhu TW, Zhang X, Zong MH, Linhardt RJ, Wu H, Li B. Storage stability studies on interesterified blend-based fast-frozen special fats for oxidative stability, crystallization characteristics and physical properties. Food Chemistry. 306: 125563. PMID 31606626 DOI: 10.1016/j.foodchem.2019.125563  1
2019 Lin L, Yu Y, Zhang F, Xia K, Zhang X, Linhardt RJ. Bottom-up and top-down profiling of pentosan polysulfate. The Analyst. PMID 31287456 DOI: 10.1039/c9an01006h  1
2019 Zhu TW, Zhang X, Zong MH, Linhardt RJ, Li B, Wu H. Interesterified blend-based and physical blend-based special fats: Storage stability under fluctuating temperatures. Journal of the Science of Food and Agriculture. PMID 31250449 DOI: 10.1002/jsfa.9894  1
2019 Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG. Increased 3'-phosphoadenosine-5'-phosphosulfate levels in engineered Escherichia coli cell lysate facilitates in vitro synthesis of Chondroitin Sulfate A. Biotechnology Journal. e1800436. PMID 31180182 DOI: 10.1002/biot.201800436  1
2019 Ahmed-Farid OA, Haredy SA, Niazy RM, Linhardt RJ, Warda M. Dose-dependent neuroprotective effect of oriental phyto-derived glycyrrhizin on experimental neuroterminal norepinephrine depletion in a rat brain model. Chemico-Biological Interactions. 308: 279-287. PMID 31150628 DOI: 10.1016/j.cbi.2019.05.045  1
2019 Yu Y, Williams A, Zhang X, Fu L, Xia K, Xu Y, Zhang F, Liu J, Koffas M, Linhardt RJ. Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei. Glycobiology. PMID 31143933 DOI: 10.1093/glycob/cwz039  1
2019 Ouyang Y, Zhu M, Wang X, Yi L, Fareed J, Linhardt RJ, Zhang Z. Systematic analysis of enoxaparins from different sources with online one- and two-dimensional chromatography. The Analyst. PMID 31016304 DOI: 10.1039/c9an00399a  1
2019 Zhang X, Han X, Xia K, Xu Y, Yang Y, Oshima K, Haeger SM, Perez MJ, McMurtry SA, Hippensteel JA, Ford JA, Herson PS, Liu J, Schmidt EP, Linhardt RJ. Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31010931 DOI: 10.1073/pnas.1902227116  1
2019 Chen J, Yu Y, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Jin C, Jin Y, Yao Y, Xia K, Zhang F, Chen S, Ye X, Linhardt RJ. Comparison of Low-Molecular-Weight Heparins Prepared From Ovine Heparins With Enoxaparin. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 25: 1076029619840701. PMID 30987427 DOI: 10.1177/1076029619840701  1
2019 Kizer ME, Linhardt RJ, Chandrasekaran AR, Wang X. A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures. Small (Weinheim An Der Bergstrasse, Germany). e1805386. PMID 30985074 DOI: 10.1002/smll.201805386  1
2019 Udangawa RN, Mikael PE, Mancinelli C, Chapman C, Willard C, Simmons TJ, Linhardt RJ. Novel Cellulose - Halloysite Hemostatic Nanocomposite Fibers with a Dramatic Reduction in Human Plasma Coagulation Time. Acs Applied Materials & Interfaces. PMID 30977359 DOI: 10.1021/acsami.9b04615  1
2019 Xu Y, Wu YJ, Sun PL, Zhang FM, Linhardt RJ, Zhang AQ. Chemically modified polysaccharides: Synthesis, characterization, structure activity relationships of action. International Journal of Biological Macromolecules. PMID 30965077 DOI: 10.1016/j.ijbiomac.2019.03.213  1
2019 Kim SY, Kundu J, Williams A, Yandulskaya AS, Monaghan JR, Carrier RL, Linhardt RJ. Glycosaminoglycans compositional analysis of Urodele axolotl (Ambystoma mexicanum) and Porcine Retina. Glycoconjugate Journal. PMID 30963354 DOI: 10.1007/s10719-019-09863-5  1
2019 Shen X, Liu Z, Li J, Wu D, Zhu M, Yan L, Mao G, Ye X, Linhardt RJ, Chen S. Development of low molecular weight heparin by HO/ascorbic acid with ultrasonic power and its anti-metastasis property. International Journal of Biological Macromolecules. PMID 30954594 DOI: 10.1016/j.ijbiomac.2019.04.019  1
2019 Carvalho MS, Silva JC, Udangawa RN, Cabral JMS, Ferreira FC, da Silva CL, Linhardt RJ, Vashishth D. Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering. Materials Science & Engineering. C, Materials For Biological Applications. 99: 479-490. PMID 30889723 DOI: 10.1016/j.msec.2019.01.127  1
2019 Cress BF, Bhaskar U, Vaidyanathan D, Williams A, Cai C, Liu X, Fu L, M-Chari V, Zhang F, Mousa SA, Dordick JS, Koffas MAG, Linhardt RJ. Heavy heparin: A stable isotope-enriched, chemoenzymatically-synthesized, poly-component drug. Angewandte Chemie (International Ed. in English). PMID 30870573 DOI: 10.1002/anie.201900768  1
2019 Wen P, Hu TG, Wen Y, Linhardt RJ, Zong MH, Zou YX, Wu H. Targeted delivery of phycocyanin for the prevention of colon cancer using electrospun fibers. Food & Function. PMID 30806395 DOI: 10.1039/c8fo02447b  1
2019 Xia K, Bao H, Zhang F, Linhardt RJ, Liang X. Characterization and comparative analysis of toxin-antitoxin systems in Acetobacter pasteurianus. Journal of Industrial Microbiology & Biotechnology. PMID 30805740 DOI: 10.1007/s10295-019-02144-y  1
2019 Cheng S, Wantuch PL, Kizer ME, Middleton DR, Wang R, DiBello M, Li M, Wang X, Li X, Ramachandiran V, Avci FY, Zhang F, Zhang X, Linhardt RJ. Glycoconjugate synthesis using chemoselective ligation. Organic & Biomolecular Chemistry. PMID 30778481 DOI: 10.1039/c9ob00270g  1
2019 Li J, Li S, Wu L, Yang H, Wei C, Ding T, Linhardt RJ, Zheng X, Ye X, Chen S. Ultrasound-assisted fast preparation of low molecular weight fucosylated chondroitin sulfate with antitumor activity. Carbohydrate Polymers. 209: 82-91. PMID 30732828 DOI: 10.1016/j.carbpol.2018.12.061  1
2019 Hippensteel JA, Anderson BJ, Orfila JE, McMurtry SA, Dietz RM, Su G, Ford JA, Oshima K, Yang Y, Zhang F, Han X, Yu Y, Liu J, Linhardt RJ, Meyer NJ, et al. Circulating heparan sulfate fragments mediate septic cognitive dysfunction. The Journal of Clinical Investigation. PMID 30720464 DOI: 10.1172/JCI124485  1
2019 Kim SY, Koetzner CA, Payne AF, Nierode GJ, Yu Y, Wang RF, Barr E, Dordick JS, Kramer L, Zhang F, Linhardt RJ. Glycosaminoglycan Compositional Analysis of Relevant Tissues in ZIKV Pathogenesis and in vitro Evaluation of Heparin as Antiviral Against ZIKV Infection. Biochemistry. PMID 30698412 DOI: 10.1021/acs.biochem.8b01267  1
2019 Silva JC, Carvalho MS, Han X, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ. Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices. Glycoconjugate Journal. PMID 30637588 DOI: 10.1007/s10719-019-09858-2  1
2019 Ouyang Y, Yu Y, Zhang F, Chen J, Han X, Xia K, Yao Y, Zhang Z, Linhardt RJ. Non-Anticoagulant Low Molecular Weight Heparins for Pharmaceutical Applications. Journal of Medicinal Chemistry. PMID 30608147 DOI: 10.1021/acs.jmedchem.8b01551  1
2019 Wei C, Zhang Y, He L, Cheng J, Li J, Tao W, Mao G, Zhang H, Linhardt RJ, Ye X, Chen S. Structural characterization and anti-proliferative activities of partially degraded polysaccharides from peach gum. Carbohydrate Polymers. 203: 193-202. PMID 30318204 DOI: 10.1016/j.carbpol.2018.09.029  1
2018 Zheng L, Zhu X, Yang K, Zhu M, Farooqi AA, Kang D, Sun M, Xu Y, Lin X, Feng Y, Liang F, Zhang F, Linhardt RJ. PBN11-8, a Cytotoxic Polypeptide Purified from Marine , Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. Polymers. 10. PMID 30960968 DOI: 10.3390/polym10091043  1
2018 He Z, Han Z, Kizer M, Linhardt RJ, Wang X, Sinyukov AM, Wang J, Deckert V, Sokolov AV, Hu J, Scully MO. Tip-enhanced Raman imaging of single-stranded DNA with single base resolution. Journal of the American Chemical Society. PMID 30586988 DOI: 10.1021/jacs.8b11506  1
2018 Mikael P, Willard C, Koyee A, Barlao CG, Liu X, Han X, Ouyang Y, Xia K, Linhardt RJ, Dordick JS. Remodeling of Glycosaminoglycans During Differentiation of Adult Human Bone Mesenchymal Stromal Cells toward Hepatocytes. Stem Cells and Development. PMID 30572803 DOI: 10.1089/scd.2018.0197  1
2018 Yu Y, Zhang F, Colón W, Linhardt RJ, Xia K. Glycosaminoglycans in human cerebrospinal fluid determined by LC-MS/MS MRM. Analytical Biochemistry. PMID 30571946 DOI: 10.1016/j.ab.2018.12.013  1
2018 Zhi Z, Li J, Chen J, Li S, Cheng H, Liu D, Ye X, Linhardt RJ, Chen S. Preparation of low molecular weight heparin using an ultrasound-assisted Fenton-system. Ultrasonics Sonochemistry. PMID 30559077 DOI: 10.1016/j.ultsonch.2018.11.016  1
2018 Ouyang Y, Han X, Xia Q, Chen J, Velagapudi S, Xia K, Zhang Z, Linhardt RJ. Negative-Ion Mode Capillary Isoelectric Focusing-Mass Spectrometry for Charge-Based Separation of Acidic Oligosaccharides. Analytical Chemistry. PMID 30516363 DOI: 10.1021/acs.analchem.8b03500  1
2018 Wang F, Zhu J, Yan T, Pei X, Zhang F, Linhardt RJ. Amphiphilic bromelain-synthesized oligo-phenylalanine grafted with methoxypolyethylene glycol possessing stabilizing thermo-responsive emulsion properties. Journal of Colloid and Interface Science. 538: 1-14. PMID 30481653 DOI: 10.1016/j.jcis.2018.11.082  1
2018 Wu F, Dong K, Zhu M, Zhang Q, Xie B, Li D, Gan H, Linhardt RJ, Zhang Z. Development of a method to analyze the complexes of enoxaparin and platelet factor 4 with size-exclusion chromatography. Journal of Pharmaceutical and Biomedical Analysis. 164: 668-671. PMID 30472585 DOI: 10.1016/j.jpba.2018.11.018  1
2018 Li J, Li S, Liu S, Wei C, Yan L, Ding T, Linhardt RJ, Liu D, Ye X, Chen S. Pectic oligosaccharides hydrolyzed from citrus canning processing water by Fenton reaction and their antiproliferation potentials. International Journal of Biological Macromolecules. PMID 30465847 DOI: 10.1016/j.ijbiomac.2018.11.166  1
2018 Li S, Li J, Mao G, Wu T, Lin D, Hu Y, Ye X, Tian D, Chai W, Linhardt RJ, Chen S. Fucosylated chondroitin sulfate from Isostichopus badionotus alleviates metabolic syndromes and gut microbiota dysbiosis induced by high-fat and high-fructose diet. International Journal of Biological Macromolecules. PMID 30465844 DOI: 10.1016/j.ijbiomac.2018.11.167  1
2018 Sladden TM, Yerkovich S, Grant M, Zhang F, Liu X, Trotter M, Hopkins P, Linhardt RJ, Chambers DC. ENDOTHELIAL GLYCOCALYX SHEDDING PREDICTS DONOR ORGAN ACCEPTABILITY AND IS ASSOCIATED WITH PRIMARY GRAFT DYSFUNCTION IN LUNG TRANSPLANT RECIPIENTS. Transplantation. PMID 30444804 DOI: 10.1097/TP.0000000000002539  1
2018 Ouyang Y, Han X, Yu Y, Chen J, Fu L, Zhang F, Linhardt RJ, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Zhang Z, Xia K. Chemometric analysis of porcine, bovine and ovine heparins. Journal of Pharmaceutical and Biomedical Analysis. 164: 345-352. PMID 30428408 DOI: 10.1016/j.jpba.2018.10.052  1
2018 Kizer M, Li P, Cress BF, Lin L, Jing TT, Zhang X, Xia K, Linhardt RJ, Wang X. RNA Aptamers with Specificity for Heparosan and Chondroitin Glycosaminoglycans. Acs Omega. 3: 13667-13675. PMID 30411046 DOI: 10.1021/acsomega.8b01853  1
2018 Yamaguchi K, Asakura K, Imamura M, Kawai G, Sakamoto T, Furihata T, Linhardt RJ, Igarashi K, Toida T, Higashi K. Polyamines stimulate the CHSY1 synthesis through the unfolding of the RNA G-quadruplex at the 5'-untraslated region. The Biochemical Journal. PMID 30401686 DOI: 10.1042/BCJ20180672  1
2018 Qiu H, Shi S, Yue J, Xin M, Nairn AV, Lin L, Liu X, Li G, Archer-Hartmann SA, Dela Rosa M, Galizzi M, Wang S, Zhang F, Azadi P, van Kuppevelt TH, ... ... Linhardt RJ, et al. A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships. Nature Methods. PMID 30377379 DOI: 10.1038/s41592-018-0189-6  1
2018 Wu YJ, Wei ZX, Zhang FM, Linhardt RJ, Sun PL, Zhang AQ. Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review. International Journal of Biological Macromolecules. PMID 30342120 DOI: 10.1016/j.ijbiomac.2018.10.117  1
2018 Gupta M, Zha J, Zhang X, Jung GY, Linhardt RJ, Koffas MAG. Production of Deuterated Cyanidin 3--Glucoside from Recombinant . Acs Omega. 3: 11643-11648. PMID 30320269 DOI: 10.1021/acsomega.8b01134  1
2018 Slaker ML, Jorgensen ET, Hegarty DM, Liu X, Kong Y, Zhang F, Linhardt RJ, Brown TE, Aicher SA, Sorg BA. Cocaine Exposure Modulates Perineuronal Nets and Synaptic Excitability of Fast-Spiking Interneurons in the Medial Prefrontal Cortex. Eneuro. 5. PMID 30294670 DOI: 10.1523/ENEURO.0221-18.2018  1
2018 Wang W, Li Y, Wang Y, Shi C, Li C, Li Q, Linhardt RJ. Bacteriophage T7 transcription system: an enabling tool in synthetic biology. Biotechnology Advances. PMID 30290194 DOI: 10.1016/j.biotechadv.2018.10.001  1
2018 Zhao J, Kong Y, Zhang F, Linhardt RJ. Impact of Temperature on Heparin and Protein Interactions. Biochemistry & Physiology. 7. PMID 30271699 DOI: 10.4172/2168-9652.1000241  1
2018 Li S, Li J, Mao G, Wu T, Hu Y, Ye X, Tian D, Linhardt RJ, Chen S. A fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated structure alleviates gut microbiota dysbiosis and metabolic syndromes in HFD-fed mice. Food & Function. PMID 30264830 DOI: 10.1039/c8fo01174e  1
2018 Feng K, Zhai M, Zhang Y, Linhardt RJ, Zong M, Li L, Wu H. Improved viability and thermal stability of the probiotics encapsulated in a novel electrospun fiber mat. Journal of Agricultural and Food Chemistry. PMID 30260640 DOI: 10.1021/acs.jafc.8b02644  1
2018 Xiao Y, Li M, Larocque R, Zhang F, Malhotra A, Chen J, Linhardt RJ, Konermann L, Xu D. Dimerization Interface of Osteoprotegerin Revealed by Hydrogen-deuterium Exchange Mass Spectrometry. The Journal of Biological Chemistry. PMID 30254073 DOI: 10.1074/jbc.RA118.004489  1
2018 Li S, Li J, Mao G, Hu Y, Ye X, Tian D, Linhardt RJ, Chen S. Fucosylated chondroitin sulfate oligosaccharides from Isostichopus badionotus regulates lipid disorder in C57BL/6 mice fed a high-fat diet. Carbohydrate Polymers. 201: 634-642. PMID 30241863 DOI: 10.1016/j.carbpol.2018.08.020  1
2018 Wang Y, Shen J, Yang X, Jin Y, Yang Z, Wang R, Zhang F, Linhardt RJ. Mechanism of enhanced oral absorption of Akebia saponin D by a self-nanoemulsifying drug delivery system loaded with phospholipid complex. Drug Development and Industrial Pharmacy. 1-19. PMID 30229685 DOI: 10.1080/03639045.2018.1526183  1
2018 Kim SY, Zhang F, Gong W, Chen K, Xia K, Liu F, Gross RA, Wang JM, Linhardt RJ, Cotten ML. Copper regulates the interactions of antimicrobial piscidin peptides from fish mast cells with formyl peptide receptors and heparin. The Journal of Biological Chemistry. PMID 30158246 DOI: 10.1074/jbc.RA118.001904  1
2018 Wang Y, Shen J, Yang X, Jin Y, Yang Z, Wang R, Zhang F, Linhardt RJ. Akebia saponin D reverses corticosterone hypersecretion in an Alzheimer's disease rat model. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 107: 219-225. PMID 30092401 DOI: 10.1016/j.biopha.2018.07.149  1
2018 Siegel RA, Brown L, Edelman ER, Linhardt RJ. B'reshith. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 252-257. PMID 30078756 DOI: 10.1016/j.jconrel.2018.07.005  0.64
2018 Xie S, Guan Y, Zhu P, Li F, Yu M, Linhardt RJ, Chi L, Jin L. Preparation of low molecular weight heparins from bovine and ovine heparins using nitrous acid degradation. Carbohydrate Polymers. 197: 83-91. PMID 30007661 DOI: 10.1016/j.carbpol.2018.05.070  1
2018 Jin W, Li S, Chen J, Liu B, Li J, Li X, Zhang F, Linhardt RJ, Zhong W. Increased soluble heterologous expression of a rat brain 3-O-sulfotransferase 1 - A key enzyme for heparin biosynthesis. Protein Expression and Purification. PMID 29894802 DOI: 10.1016/j.pep.2018.06.007  1
2018 Yu Y, Linhardt RJ. Xylosyltransferase 1 and the GAG Attachment Site. Structure (London, England : 1993). 26: 797-799. PMID 29874596 DOI: 10.1016/j.str.2018.05.011  1
2018 Hart T, Nguyen NTT, Nowak NA, Zhang F, Linhardt RJ, Diuk-Wasser M, Ram S, Kraiczy P, Lin YP. Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission. Plos Pathogens. 14: e1007106. PMID 29813137 DOI: 10.1371/journal.ppat.1007106  1
2018 Bhattacharyya S, Feferman L, Han X, Ouyang Y, Zhang F, Linhardt RJ, Tobacman JK. Decline in Arylsulfatase B Expression Increases EGFR Expression by Inhibiting the Protein Tyrosine Phosphatase SHP2 and Activating JNK in Prostate Cells. The Journal of Biological Chemistry. PMID 29794138 DOI: 10.1074/jbc.RA117.001244  1
2018 Peng X, Peng Y, Han B, Liu W, Zhang F, Linhardt RJ. IO4--stimulated crosslinking of catechol-conjugated hydroxyethyl chitosan as a tissue adhesive. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 29732734 DOI: 10.1002/jbm.b.34150  1
2018 Zhang X, Xia K, Lin L, Zhang F, Yu Y, St Ange K, Han X, Edsinger E, Sohn JJ, Linhardt RJ. Structural and functional components of the skate sensory organ ampullae of Lorenzini. Acs Chemical Biology. PMID 29708722 DOI: 10.1021/acschembio.8b00335  1
2018 Zheng L, Lin X, Yuan Z, Liu M, Cao S, Zhang F, Linhardt RJ. Recent Progress of Marine Polypeptides as Anticancer Agents Marine Polypeptides as Anticancer Agents. Recent Patents On Anti-Cancer Drug Discovery. PMID 29708076 DOI: 10.2174/1574892813666180430110033  1
2018 Li Q, Li G, Zhao X, Shan X, Cai C, Zhao J, Zhang F, Linhardt RJ, Yu G. Structural Characterization and Interaction with RCA of a Highly Sulfated Keratan Sulfate from Blue Shark (Prionace glauca) Cartilage. Marine Drugs. 16. PMID 29662015 DOI: 10.3390/md16040128  1
2018 Zhang A, Deng J, Yu S, Zhang F, Linhardt RJ, Sun P. Purification and structural elucidation of a water-soluble polysaccharide from the fruiting bodies of the Grifola frondosa. International Journal of Biological Macromolecules. PMID 29660454 DOI: 10.1016/j.ijbiomac.2018.04.061  1
2018 Haeger SM, Liu X, Han X, McNeil JB, Oshima K, McMurtry SA, Yang Y, Ouyang Y, Zhang F, Nozik-Grayck E, Zemans RL, Tuder RM, Bastarache JA, Linhardt RJ, Schmidt EP. Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and is Shed During Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 29584451 DOI: 10.1165/rcmb.2017-0428OC  1
2018 Khan S, Liu J, Szabo Z, Kunnummal B, Han X, Ouyang Y, Linhardt RJ, Xia Q. On-Line CE-LIF-MS Analysis of Glycans Labeled with Teal Fluorescent Dye using Electrokinetic Sheath Liquid Pump-based Nanospray Ion Source. Rapid Communications in Mass Spectrometry : Rcm. PMID 29575162 DOI: 10.1002/rcm.8116  1
2018 Zhang A, Deng J, Liu X, He P, He L, Zhang F, Linhardt RJ, Sun P. Structure and conformation of α-glucan extracted from Agaricus blazei Murill by high-speed shearing homogenization. International Journal of Biological Macromolecules. PMID 29501839 DOI: 10.1016/j.ijbiomac.2018.02.151  1
2018 Sanderson P, Stickney M, Leach FE, Xia Q, Yu Y, Zhang F, Linhardt RJ, Amster IJ. Heparin/heparan sulfate analysis by covalently modified reverse polarity capillary zone electrophoresis-mass spectrometry. Journal of Chromatography. A. PMID 29501428 DOI: 10.1016/j.chroma.2018.02.052  1
2018 Okamoto Y, Higashi K, Linhardt RJ, Toida T. Comprehensive analysis of glycosaminoglycans from the edible shellfish. Carbohydrate Polymers. 184: 269-276. PMID 29352919 DOI: 10.1016/j.carbpol.2017.12.076  1
2018 Wang Z, Zhang T, Xie S, Liu X, Li H, Linhardt RJ, Chi L. Sequencing the oligosaccharide pool in the low molecular weight heparin dalteparin with offline HPLC and ESI-MS/MS. Carbohydrate Polymers. 183: 81-90. PMID 29352895 DOI: 10.1016/j.carbpol.2017.11.039  1
2018 Chen Y, Zhao J, Yu Y, Liu X, Lin L, Zhang F, Linhardt RJ. Antithrombin III Binding Site Analysis of Low Molecular Weight Heparin Fractions. Journal of Pharmaceutical Sciences. PMID 29339133 DOI: 10.1016/j.xphs.2018.01.008  1
2018 Shirke AN, White C, Englaender JA, Zwarycz AS, Butterfoss GL, Linhardt RJ, Gross RA. Stabilizing leaf and branch compost cutinase (LCC) with glycosylation: Mechanism and effect on PET hydrolysis. Biochemistry. PMID 29328676 DOI: 10.1021/acs.biochem.7b01189  1
2018 Peng Y, Yu Y, Lin L, Liu X, Zhang X, Wang P, Hoffman P, Kim SY, Zhang F, Linhardt RJ. Glycosaminoglycans from bovine eye vitreous humour and interaction with collagen type II. Glycoconjugate Journal. PMID 29305777 DOI: 10.1007/s10719-017-9808-1  1
2018 Li Q, Cai C, Chang Y, Zhang F, Linhardt RJ, Xue C, Li G, Yu G. A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulation. Carbohydrate Polymers. 181: 1160-1168. PMID 29253945 DOI: 10.1016/j.carbpol.2017.10.100  1
2017 Hou L, Zhang X, Mikael PE, Lin L, Dong W, Zheng Y, Simmons TJ, Zhang F, Linhardt RJ. Biodegradable and Bioactive PCL-PGS Core-Shell Fibers for Tissue Engineering. Acs Omega. 2: 6321-6328. PMID 30023516 DOI: 10.1021/acsomega.7b00460  1
2017 Zhang X, Pagadala V, Jester HM, Lim AM, Pham TQ, Goulas AMP, Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists. Chemical Science. 8: 7932-7940. PMID 29568440 DOI: 10.1039/c7sc03541a  1
2017 Sun X, Tao L, Yi L, Ouyang Y, Xu N, Li D, Linhardt RJ, Zhang Z. N-glycans released from glycoproteins using a commercial kit and comprehensively analyzed with a hypothetical database. Journal of Pharmaceutical Analysis. 7: 87-94. PMID 29404022 DOI: 10.1016/j.jpha.2017.01.004  1
2017 Badri A, Williams A, Linhardt RJ, Koffas MA. The road to animal-free glycosaminoglycan production: current efforts and bottlenecks. Current Opinion in Biotechnology. 53: 85-92. PMID 29291494 DOI: 10.1016/j.copbio.2017.12.018  1
2017 Agyekum I, Pepi L, Yu Y, Li J, Yan L, Linhardt RJ, Chen S, Amster IJ. Structural elucidation of fucosylated chondroitin sulfates from sea cucumber using FTICR-MS/MS. European Journal of Mass Spectrometry (Chichester, England). 1469066717731900. PMID 29232996 DOI: 10.1177/1469066717731900  1
2017 Ming SA, Cottman-Thomas E, Black NC, Chen Y, Veeramachineni V, Peterson DC, Chen X, Tedaldi LM, Wagner GK, Cai C, Linhardt RJ, Vann WF. Interaction of Neisseria meningitidis Group X N-Acetylglucosamine-1-phosphotransferase with Its Donor Substrate. Glycobiology. PMID 29228283 DOI: 10.1093/glycob/cwx100  1
2017 Middleton DR, Zhang X, Wantuch PL, Ozdilek A, Liu X, Lopilato R, Gangasani N, Bridger R, Wells L, Linhardt RJ, Avci FY. Identification and characterization of the Streptococcus pneumoniae type 3 capsule-specific glycoside hydrolase of Paenibacillus species 32352. Glycobiology. PMID 29190349 DOI: 10.1093/glycob/cwx097  1
2017 Li J, Qian S, Xiong L, Zhu C, Shu M, Wang J, Jiao Y, He H, Zhang F, Linhardt RJ, Zhong W. Comparative Genomics Reveals Specific Genetic Architectures in Nicotine Metabolism of Pseudomonas sp. JY-Q. Frontiers in Microbiology. 8: 2085. PMID 29163390 DOI: 10.3389/fmicb.2017.02085  1
2017 Pan Y, Wang P, Zhang F, Yu Y, Zhang X, Lin L, Linhardt RJ. Glycosaminoglycans from fish swim bladder: isolation, structural characterization and bioactive potential. Glycoconjugate Journal. PMID 29124565 DOI: 10.1007/s10719-017-9804-5  1
2017 Lin YP, Li L, Zhang F, Linhardt RJ. Borrelia burgdorferi glycosaminoglycan-binding proteins: a potential target for new therapeutics against Lyme disease. Microbiology (Reading, England). PMID 29116038 DOI: 10.1099/mic.0.000571  1
2017 Yu Y, Duan J, Leach Iii FE, Toida T, Higashi K, Zhang H, Zhang F, Amster IJ, Linhardt RJ. Sequencing the Dermatan Sulfate Chain of Decorin. Journal of the American Chemical Society. PMID 29111696 DOI: 10.1021/jacs.7b10164  1
2017 Yan L, Li J, Wang D, Ding T, Hu Y, Ye X, Linhardt RJ, Chen S. Molecular size is important for the safety and selective inhibition of intrinsic factor Xase for fucosylated chondroitin sulfate. Carbohydrate Polymers. 178: 180-189. PMID 29050584 DOI: 10.1016/j.carbpol.2017.09.034  1
2017 Fu L, Li K, Mori D, Hirakane M, Lin L, Grover N, Datta P, Yu Y, Zhao J, Zhang F, Yalcin M, Mousa SA, Dordick JS, Linhardt RJ. Enzymatic generation of highly anticoagulant bovine intestinal heparin. Journal of Medicinal Chemistry. PMID 28972371 DOI: 10.1021/acs.jmedchem.7b01269  1
2017 Ouyang Y, Zeng Y, Yi L, Tang H, Li D, Linhardt RJ, Zhang Z. Qualitative and quantitative analysis of heparin and low molecular weight heparins using size exclusion chromatography with multiple angle laser scattering/refractive index and inductively coupled plasma/mass spectrometry detectors. Journal of Chromatography. A. PMID 28958760 DOI: 10.1016/j.chroma.2017.09.040  1
2017 Wen P, Wen Y, Zong M, Linhardt RJ, Wu H. Encapsulation of bioactive compound in electrospun fibers and its potential application. Journal of Agricultural and Food Chemistry. PMID 28949530 DOI: 10.1021/acs.jafc.7b02956  1
2017 Xu Y, Chandarajoti K, Zhang X, Pagadala V, Dou W, Hoppensteadt DM, Sparkenbaugh EM, Cooley B, Daily S, Key NS, Severynse-Stevens D, Fareed J, Linhardt RJ, Pawlinski R, Liu J. Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins. Science Translational Medicine. 9. PMID 28878012 DOI: 10.1126/scitranslmed.aan5954  1
2017 Li G, Li L, Joo EJ, Son JW, Kim YJ, Kang JK, Lee KB, Zhang F, Linhardt RJ. Glycosaminoglycans and glycolipids as potential biomarkers in lung cancer. Glycoconjugate Journal. PMID 28822024 DOI: 10.1007/s10719-017-9790-7  1
2017 Zhang X, Green DE, Schultz VL, Lin L, Han X, Wang R, Yaksic A, Kim SY, DeAngelis PL, Linhardt RJ. Synthesis of 4-azido-N-acetylhexosamine uridine diphosphate donors: Clickable glycosaminoglycans. The Journal of Organic Chemistry. PMID 28813597 DOI: 10.1021/acs.joc.7b01787  1
2017 Li J, Li S, Yan L, Ding T, Linhardt RJ, Yu Y, Liu X, Liu D, Ye X, Chen S. Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation: Importance of sulfation pattern and molecular size. European Journal of Medicinal Chemistry. 139: 191-200. PMID 28800457 DOI: 10.1016/j.ejmech.2017.07.065  1
2017 Williams A, He W, Cress BF, Liu X, Alexandria J, Yoshizawa H, Nishimura K, Toida T, Koffas M, Linhardt RJ. Cloning and expression of recombinant chondroitinase AC II and its comparison to the Arthrobacter aurescens enzyme. Biotechnology Journal. PMID 28799715 DOI: 10.1002/biot.201700239  1
2017 He W, Zhu Y, Shirke A, Sun X, Liu J, Gross RA, Koffas MAG, Linhardt RJ, Li M. Expression of chondroitin-4-O-sulfotransferase in Escherichia coli and Pichia pastoris. Applied Microbiology and Biotechnology. PMID 28761999 DOI: 10.1007/s00253-017-8411-5  1
2017 Liu Z, Song L, Lu L, Zhang X, Zhang F, Wang K, Linhardt RJ. Comparative proteomics of matrix fractions between pimpled and normal chicken eggshells. Journal of Proteomics. PMID 28755913 DOI: 10.1016/j.jprot.2017.07.015  1
2017 Wang H, He W, Jiang P, Yu Y, Lin L, Sun X, Koffas M, Zhang F, Linhardt RJ. Construction and functional characterization of truncated versions of recombinant keratanase II from Bacillus circulans. Glycoconjugate Journal. PMID 28752383 DOI: 10.1007/s10719-017-9786-3  1
2017 Li S, Li J, Zhi Z, Wei C, Wang W, Ding T, Ye X, Hu Y, Linhardt RJ, Chen S. Macromolecular properties and hypolipidemic effects of four sulfated polysaccharides from sea cucumbers. Carbohydrate Polymers. 173: 330-337. PMID 28732873 DOI: 10.1016/j.carbpol.2017.05.063  1
2017 Fulcher YG, Prior SH, Masuko S, Li L, Pu D, Zhang F, Linhardt RJ, Van Doren SR. Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7. Structure (London, England : 1993). PMID 28648610 DOI: 10.1016/j.str.2017.05.019  1
2017 Jones JA, Vernacchio VR, Collins SM, Shirke AN, Xiu Y, Englaender JA, Cress BF, McCutcheon CC, Linhardt RJ, Gross RA, Koffas MAG. Complete Biosynthesis of Anthocyanins Using E. coli Polycultures. Mbio. 8. PMID 28588129 DOI: 10.1128/mBio.00621-17  1
2017 Dumont CM, Piselli J, Kazi N, Bowman E, Li G, Linhardt RJ, Temple S, Dai G, Thompson DM. Factors released from endothelial cells exposed to flow impact adhesion, proliferation, and fate choice in the adult neural stem cell lineage. Stem Cells and Development. PMID 28557666 DOI: 10.1089/scd.2016.0350  1
2017 Yu Y, Hirakane M, Mori D, Lin L, Zhang F, Zhang H, Linhardt RJ. Structural and activity variability of fractions with different charge density and chain length from pharmaceutical heparins. Glycoconjugate Journal. PMID 28555433 DOI: 10.1007/s10719-017-9774-7  1
2017 Xiu Y, Jang S, Jones JA, Zill NA, Linhardt RJ, Yuan Q, Jung GY, Koffas MAG. Naringenin-Responsive Riboswitch-Based Fluorescent Biosensor Module for Escherichia coli Co-cultures. Biotechnology and Bioengineering. PMID 28543037 DOI: 10.1002/bit.26340  1
2017 Wang W, Zhang C, Sun X, Su S, Li Q, Linhardt RJ. Efficient, environmentally-friendly and specific valorization of lignin: promising role of non-radical lignolytic enzymes. World Journal of Microbiology & Biotechnology. 33: 125. PMID 28540631 DOI: 10.1007/s11274-017-2286-6  1
2017 Vaidyanathan D, Williams A, Dordick JS, Koffas MAG, Linhardt RJ. Engineered heparins as new anticoagulant drugs. Bioengineering & Translational Medicine. 2: 17-30. PMID 28516163 DOI: 10.1002/btm2.10042  1
2017 Xie Q, Spear JM, Noble AJ, Sousa DR, Meyer NL, Davulcu O, Zhang F, Linhardt RJ, Stagg SM, Chapman MS. The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide. Molecular Therapy. Methods & Clinical Development. 5: 1-12. PMID 28480299 DOI: 10.1016/j.omtm.2017.02.004  1
2017 Kim SY, Li B, Linhardt RJ. Pathogenesis and Inhibition of Flaviviruses from a Carbohydrate Perspective. Pharmaceuticals (Basel, Switzerland). 10. PMID 28471403 DOI: 10.3390/ph10020044  1
2017 Su G, Li L, Huang H, Zhong W, Yu P, Zhang F, Linhardt RJ. Corrigendum to "Production of a low molecular weight heparin production using recombinant glycuronidas"[Carbohydr. Polym., 134 (2015) 151-157]. Carbohydrate Polymers. 167: 364. PMID 28433174 DOI: 10.1016/j.carbpol.2017.03.055  1
2017 Wei CY, Liao NB, Zhang Y, Ye XQ, Li S, Hu YQ, Liu DH, Linhardt RJ, Wang X, Chen SG. In vitro fermentation behaviors of fucosylated chondroitin sulfate from Pearsonothuria graeffei by human gut microflora. International Journal of Biological Macromolecules. PMID 28431945 DOI: 10.1016/j.ijbiomac.2017.04.036  1
2017 Sommers CD, Ye H, Liu J, Linhardt RJ, Keire DA. Heparin and homogeneous model heparin oligosaccharides form distinct complexes with protamine: Light scattering and zeta potential analysis. Journal of Pharmaceutical and Biomedical Analysis. 140: 113-121. PMID 28346881 DOI: 10.1016/j.jpba.2017.03.010  1
2017 Lane RS, St Ange K, Zolghadr B, Liu X, Schäffer C, Linhardt RJ, DeAngelis PL. Expanding glycosaminoglycan chemical space: towards the creation of sulfated analogs, novel polymers and chimeric constructs. Glycobiology. 1-11. PMID 28334971 DOI: 10.1093/glycob/cwx021  1
2017 Zhao J, Liu X, Malhotra A, Li Q, Zhang F, Linhardt RJ. Novel method for measurement of heparin anticoagulant activity using SPR. Analytical Biochemistry. 526: 39-42. PMID 28322799 DOI: 10.1016/j.ab.2017.03.013  1
2017 Vongchan P, Linhardt RJ. Characterization of a new monoclonal anti-glypican-3 antibody specific to the hepatocellular carcinoma cell line, HepG2. World Journal of Hepatology. 9: 368-384. PMID 28321273 DOI: 10.4254/wjh.v9.i7.368  1
2017 Zhao J, Huvent I, Lippens G, Eliezer D, Zhang A, Li Q, Tessier P, Linhardt RJ, Zhang F, Wang C. Glycan Determinants of Heparin-Tau Interaction. Biophysical Journal. 112: 921-932. PMID 28297651 DOI: 10.1016/j.bpj.2017.01.024  1
2017 Zhao J, Zhang F, Liu X, St Ange K, Zhang A, Li Q, Linhardt RJ. Isolation of a lectin binding rhamnogalacturonan-I containing pectic polysaccharide from pumpkin. Carbohydrate Polymers. 163: 330-336. PMID 28267513 DOI: 10.1016/j.carbpol.2017.01.067  1
2017 Zhu Y, Liang X, Zhang H, Feng W, Liu Y, Zhang F, Linhardt RJ. A comparative secretome analysis of industrial Aspergillus oryzae and its spontaneous mutant ZJGS-LZ-21. International Journal of Food Microbiology. 248: 1-9. PMID 28237882 DOI: 10.1016/j.ijfoodmicro.2017.02.003  1
2017 Liu X, St Ange K, Wang X, Lin L, Zhang F, Chi L, Linhardt RJ. Parent heparin and daughter LMW heparin correlation analysis using LC-MS and NMR. Analytica Chimica Acta. 961: 91-99. PMID 28224913 DOI: 10.1016/j.aca.2017.01.042  1
2017 Yang Y, Haeger SM, Suflita MA, Zhang F, Dailey KL, Colbert JF, Ford JA, Picon MA, Stearman RS, Lin L, Liu X, Han X, Linhardt RJ, Schmidt EP. Fibroblast Growth Factor Signaling Mediates Pulmonary Endothelial Glycocalyx Reconstitution. American Journal of Respiratory Cell and Molecular Biology. PMID 28187268 DOI: 10.1165/rcmb.2016-0338OC  1
2017 Minteer CJ, Siegart NM, Colelli KM, Liu X, Linhardt RJ, Wang C, Gomez AV, Reitter JN, Mills KV. Intein-promoted cyclization of aspartic acid flanking the intein leads to atypical N-terminal cleavage. Biochemistry. PMID 28165720 DOI: 10.1021/acs.biochem.6b00894  1
2017 Kim SY, Zhao J, Liu X, Fraser K, Lin L, Zhang X, Zhang F, Dordick JS, Linhardt RJ. Interaction of Zika Virus Envelope Protein with Glycosaminoglycans. Biochemistry. PMID 28151637 DOI: 10.1021/acs.biochem.6b01056  1
2017 Volpi S, Yamazaki Y, Brauer PM, van Rooijen E, Hayashida A, Slavotinek A, Sun Kuehn H, Di Rocco M, Rivolta C, Bortolomai I, Du L, Felgentreff K, Ott de Bruin L, Hayashida K, Freedman G, ... ... Linhardt RJ, et al. EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. The Journal of Experimental Medicine. PMID 28148688 DOI: 10.1084/jem.20161525  1
2017 Schultz VL, Zhang X, Linkens K, Rimel J, Green DE, DeAngelis PL, Linhardt RJ. Chemoenzymatic Synthesis of 4-Fluoro-N-Acetylhexosamine Uridine Diphosphate Donors: Chain Terminators in Glycosaminoglycan Synthesis. The Journal of Organic Chemistry. PMID 28128958 DOI: 10.1021/acs.joc.6b02929  1
2017 Yang J, Hsieh PH, Liu X, Zhou W, Zhang X, Zhao J, Xu Y, Zhang F, Linhardt RJ, Liu J. Construction and characterisation of a heparan sulphate heptasaccharide microarray. Chemical Communications (Cambridge, England). PMID 28106177 DOI: 10.1039/c6cc08204a  1
2017 Cress BF, Leitz QD, Kim DC, Amore TD, Suzuki JY, Linhardt RJ, Koffas MA. CRISPRi-mediated metabolic engineering of E. coli for O-methylated anthocyanin production. Microbial Cell Factories. 16: 10. PMID 28095853 DOI: 10.1186/s12934-016-0623-3  1
2017 Zhang X, Xu Y, Hsieh PH, Liu J, Lin L, Schmidt EP, Linhardt RJ. Chemoenzymatic synthesis of unmodified heparin oligosaccharides: cleavage of p-nitrophenyl glucuronide by alkaline and Smith degradation. Organic & Biomolecular Chemistry. PMID 28091666 DOI: 10.1039/c6ob02603f  1
2017 Liu X, St Ange K, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Chi L, Jin C, Jin Y, Yao Y, Linhardt RJ. Comparison of Low-Molecular-Weight Heparins Prepared From Bovine Heparins With Enoxaparin. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 1076029616686422. PMID 28056526 DOI: 10.1177/1076029616686422  1
2017 Englaender JA, Jones JA, Cress BF, Kuhlman TE, Linhardt RJ, Koffas MA. Effect of Genomic Integration Location on Heterologous Protein Expression and Metabolic Engineering in E. coli. Acs Synthetic Biology. PMID 28055177 DOI: 10.1021/acssynbio.6b00350  1
2017 Tao L, Song F, Xu N, Li D, Linhardt RJ, Zhang Z. New insights into the action of bacterial chondroitinase AC I and hyaluronidase on hyaluronic acid. Carbohydrate Polymers. 158: 85-92. PMID 28024546 DOI: 10.1016/j.carbpol.2016.12.010  1
2017 Chen Y, St Ange K, Lin L, Liu X, Zhang X, Linhardt RJ. Quantitative analysis of the major linkage region tetrasaccharides in heparin. Carbohydrate Polymers. 157: 244-250. PMID 27987924 DOI: 10.1016/j.carbpol.2016.09.081  1
2017 Hao J, Xu S, Xu N, Li D, Linhardt RJ, Zhang Z. Impact of degree of oxidation on the physicochemical properties of microcrystalline cellulose. Carbohydrate Polymers. 155: 483-490. PMID 27702538 DOI: 10.1016/j.carbpol.2016.09.012  1
2016 Wang ZP, Shen JZ, Linhardt RJ, Jiang H, Cheng LL. Liquid to liquid extraction and liquid chromatography-tandem mass spectrometry determination of hainanmycin in feed. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1046: 98-101. PMID 28152455 DOI: 10.1016/j.jchromb.2016.12.021  0.92
2016 Schultz V, Suflita M, Liu X, Zhang X, Yu Y, Li L, Green DE, Xu Y, Zhang F, DeAngelis PL, Liu J, Linhardt RJ. Heparan sulfate domains required for fibroblast growth factor 1 and 2 signaling through fibroblast growth factor receptor 1c. The Journal of Biological Chemistry. PMID 28031461 DOI: 10.1074/jbc.M116.761585  1
2016 Liu LP, Zong MH, Linhardt RJ, Lou WY, Li N, Huang C, Wu H. Mechanistic insights into the effect of imidazolium ionic liquid on lipid production by Geotrichum fermentans. Biotechnology For Biofuels. 9: 266. PMID 28018484 DOI: 10.1186/s13068-016-0682-z  1
2016 Liu X, St Ange K, Lin L, Zhang F, Chi L, Linhardt RJ. Top-down and bottom-up analysis of commercial enoxaparins. Journal of Chromatography. A. PMID 28011077 DOI: 10.1016/j.chroma.2016.12.021  1
2016 Chen Y, Lin L, Agyekum I, Zhang X, St Ange K, Yu Y, Zhang F, Liu J, Amster IJ, Linhardt RJ. Structural Analysis of Heparin-Derived 3-O-Sulfated Tetrasaccharides: Antithrombin Binding Site Variants. Journal of Pharmaceutical Sciences. PMID 28007564 DOI: 10.1016/j.xphs.2016.11.023  1
2016 Ibrahim MH, Cress BF, Linhardt RJ, Koffas MA, Gross RA. Draft Genome Sequence of Bacillus subtilis Ia1a, a New Strain for Poly-γ-Glutamic Acid and Exopolysaccharide Production. Genome Announcements. 4. PMID 27979935 DOI: 10.1128/genomeA.01361-16  1
2016 Englaender JA, Zhu Y, Shirke AN, Lin L, Liu X, Zhang F, Gross RA, Koffas MA, Linhardt RJ. Expression and secretion of glycosylated heparin biosynthetic enzymes using Komagataella pastoris. Applied Microbiology and Biotechnology. PMID 27975137 DOI: 10.1007/s00253-016-8047-x  1
2016 Li P, Linhardt RJ, Cao Z. Structural Characterization of Oligochitosan Elicitor from Fusarium sambucinum and Its Elicitation of Defensive Responses in Zanthoxylum bungeanum. International Journal of Molecular Sciences. 17. PMID 27973408 DOI: 10.3390/ijms17122076  1
2016 Wang X, Liu X, Li L, Zhang F, Hu M, Ren F, Chi L, Linhardt RJ. GlycCompSoft: Software for Automated Comparison of Low Molecular Weight Heparins Using Top-Down LC/MS Data. Plos One. 11: e0167727. PMID 27942011 DOI: 10.1371/journal.pone.0167727  1
2016 Sun X, Guo Z, Yu M, Lin C, Sheng A, Wang Z, Linhardt RJ, Chi L. Hydrophilic interaction chromatography-multiple reaction monitoring mass spectrometry method for basic building block analysis of low molecular weight heparins prepared through nitrous acid depolymerization. Journal of Chromatography. A. PMID 27923477 DOI: 10.1016/j.chroma.2016.11.061  1
2016 Kwon SJ, Na DH, Kwak JH, Douaisi M, Zhang F, Park EJ, Park JH, Youn H, Song CS, Kane RS, Dordick JS, Lee KB, Linhardt RJ. Nanostructured glycan architecture is important in the inhibition of influenza A virus infection. Nature Nanotechnology. PMID 27775724 DOI: 10.1038/nnano.2016.181  1
2016 Chen Y, Reddy M, Yu Y, Zhang F, Linhardt RJ. Glycosaminoglycans from chicken muscular stomach or gizzard. Glycoconjugate Journal. PMID 27752801 DOI: 10.1007/s10719-016-9737-4  1
2016 Yu Y, Chen Y, Mikael P, Zhang F, Stalcup AM, German R, Gould F, Ohlemacher J, Zhang H, Linhardt RJ. Surprising absence of heparin in the intestinal mucosa of baby pigs. Glycobiology. PMID 27744271 DOI: 10.1093/glycob/cww104  1
2016 Zhao Y, Singh A, Xu Y, Zong C, Zhang F, Boons GJ, Liu J, Linhardt RJ, Woods RJ, Amster IJ. Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study. Journal of the American Society For Mass Spectrometry. PMID 27663556 DOI: 10.1007/s13361-016-1496-8  1
2016 Imamura M, Higashi K, Yamaguchi K, Asakura K, Furihata T, Terui Y, Satake T, Maegawa J, Yasumura K, Ibuki A, Akase T, Nishimura K, Kashiwagi K, Linhardt RJ, Igarashi K, et al. Polyamines release the let-7b-mediated suppression of initiation codon recognition during the protein synthesis of EXT2. Scientific Reports. 6: 33549. PMID 27650265 DOI: 10.1038/srep33549  1
2016 Higashi K, Takeda K, Mukuno A, Okamoto Y, Masuko S, Linhardt RJ, Toida T. Identification of Keratan Sulfate Disaccharide at C-3 position of Glucuronate of Chondroitin Sulfate from Mactra Chinensis. The Biochemical Journal. PMID 27647934 DOI: 10.1042/BCJ20160655  1
2016 Ulaganathan T, Shi R, Yao D, Gu RX, Garron ML, Cherney M, Tieleman DP, Sterner E, Li G, Li L, Linhardt RJ, Cygler M. Conformational Flexibility of PL12 family Heparinases: Structure and Substrate Specificity of Heparinase III from Bacteroides thetaiotaomicron (BT4657). Glycobiology. PMID 27621378 DOI: 10.1093/glycob/cww096  1
2016 Wang YJ, Lin L, Zhang X, Schultz V, Zhang F, Sun JZ, Linhardt RJ. Selective, switchable fluorescent probe for heparin based on aggregation-induced emission. Analytical Biochemistry. PMID 27619488 DOI: 10.1016/j.ab.2016.09.007  1
2016 He P, Zhang A, Zhou S, Zhang F, Linhardt RJ, Sun P. Structural elucidation of polysaccharide containing 3-O-methyl galactose from fruiting bodies of Pleurotus citrinopileatus. Carbohydrate Research. 434: 72-76. PMID 27599128 DOI: 10.1016/j.carres.2016.08.006  1
2016 Rubinson KA, Chen Y, Cress BF, Zhang F, Linhardt RJ. Heparin's Solution Structure Determined by Small-Angle Neutron Scattering (SANS). Biopolymers. PMID 27543274 DOI: 10.1002/bip.22936  1
2016 He P, Zhang A, Zhang F, Linhardt RJ, Sun P. Structure and bioactivity of a polysaccharide containing uronic acid from Polyporus umbellatus sclerotia. Carbohydrate Polymers. 152: 222-30. PMID 27516268 DOI: 10.1016/j.carbpol.2016.07.010  1
2016 Zhao J, Liu X, Kao C, Zhang EK, Li Q, Zhang F, Linhardt RJ. Kinetic and Structural Studies on Interactions between Glycosaminoglycans and Langerin. Biochemistry. PMID 27447199 DOI: 10.1021/acs.biochem.6b00555  1
2016 Sun X, Sheng A, Liu X, Shi F, Jin L, Xie S, Zhang F, Linhardt RJ, Chi L. Comprehensive identification and quantitation of basic building blocks for low molecular weight heparin. Analytical Chemistry. PMID 27388010 DOI: 10.1021/acs.analchem.6b01709  1
2016 Dimitrievska S, Gui L, Weyers A, Lin T, Cai C, Woo W, Tuggle CT, Sundaram S, Balestrini JL, Slattery D, Tchouta L, Kyriakides TR, Tarbell JM, Linhardt RJ, Niklason LE. New Functional Tools for Antithrombogenic Activity Assessment of Live Surface Glycocalyx. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27386939 DOI: 10.1161/ATVBAHA.116.308023  1
2016 Oduah EI, Linhardt RJ, Sharfstein ST. Heparin: Past, Present, and Future. Pharmaceuticals (Basel, Switzerland). 9. PMID 27384570 DOI: 10.3390/ph9030038  1
2016 Lin L, Liu X, Zhang F, Chi L, Amster IJ, Leach FE, Xia Q, Linhardt RJ. Analysis of heparin oligosaccharides by capillary electrophoresis-negative-ion electrospray ionization mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 27325464 DOI: 10.1007/s00216-016-9662-1  1
2016 Mulloy B, Wu N, Gyapon-Quast F, Lin L, Zhang F, Pickering MC, Linhardt RJ, Feizi T, Chai W. Abnormally high content of free glucosamine residues identified in a preparation of commercially available porcine intestinal heparan sulfate. Analytical Chemistry. PMID 27295282 DOI: 10.1021/acs.analchem.6b01662  1
2016 Szajek AY, Chess E, Johansen K, Gratzl G, Gray E, Keire D, Linhardt RJ, Liu J, Morris T, Mulloy B, Nasr M, Shriver Z, Torralba P, Viskov C, Williams R, et al. The US regulatory and pharmacopeia response to the global heparin contamination crisis. Nature Biotechnology. 34: 625-630. PMID 27281424 DOI: 10.1038/nbt.3606  1
2016 Guan Y, Xu X, Liu X, Sheng A, Jin L, Linhardt RJ, Chi L. Comparison of Low-Molecular-Weight Heparins Prepared From Bovine Lung Heparin and Porcine Intestine Heparin. Journal of Pharmaceutical Sciences. 105: 1843-50. PMID 27238483 DOI: 10.1016/j.xphs.2016.03.037  1
2016 Zhang X, Khalidi O, Kim SY, Wang R, Schultz V, Cress BF, Gross RA, Koffas MA, Linhardt RJ. Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents. Bioorganic & Medicinal Chemistry Letters. PMID 27210435 DOI: 10.1016/j.bmcl.2016.05.003  1
2016 Koh A, Linhardt RJ, Gross RA. Effect of sophorolipid n-alkyl ester chain length on its interfacial properties at the almond oil-water interface. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27159768 DOI: 10.1021/acs.langmuir.6b01008  1
2016 Ge D, Higashi K, Ito D, Nagano K, Ishikawa R, Terui Y, Higashi K, Moribe K, Linhardt RJ, Toida T. Poly-ion Complex of Chondroitin Sulfate and Spermine and Its Effect on Oral Chondroitin Sulfate Bioavailability. Chemical & Pharmaceutical Bulletin. 64: 390-8. PMID 27150471 DOI: 10.1248/cpb.c15-00940  1
2016 Hao J, Lu J, Xu N, Linhardt RJ, Zhang Z. Specific oxidation pattern of soluble starch with TEMPO-NaBr-NaClO system. Carbohydrate Polymers. 146: 238-44. PMID 27112871 DOI: 10.1016/j.carbpol.2016.03.040  1
2016 Onishi A, St Ange K, Dordick JS, Linhardt RJ. Heparin and anticoagulation. Frontiers in Bioscience (Landmark Edition). 21: 1372-92. PMID 27100512  1
2016 St Ange K, Onishi A, Fu L, Sun X, Lin L, Mori D, Zhang F, Dordick JS, Fareed J, Hoppensteadt D, Jeske W, Linhardt RJ. Analysis of Heparins Derived From Bovine Tissues and Comparison to Porcine Intestinal Heparins. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. PMID 27084870 DOI: 10.1177/1076029616643822  1
2016 Cress BF, Jones JA, Kim DC, Leitz QD, Englaender JA, Collins SM, Linhardt RJ, Koffas MA. Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli. Nucleic Acids Research. PMID 27079979 DOI: 10.1093/nar/gkw231  1
2016 Huang H, Liu X, Lv S, Zhong W, Zhang F, Linhardt RJ. Recombinant Escherichia coli K5 strain with the deletion of waaR gene decreases the molecular weight of the heparosan capsular polysaccharide. Applied Microbiology and Biotechnology. PMID 27079575 DOI: 10.1007/s00253-016-7511-y  1
2016 Schmidt EP, Overdier KH, Sun X, Lin L, Liu X, Yang Y, Ammons LA, Hiller TD, Suflita MA, Yu Y, Chen Y, Zhang F, Cothren Burlew C, Edelstein CL, Douglas IS, ... Linhardt RJ, et al. Urinary Glycosaminoglycans Predict Outcomes in Septic Shock and ARDS. American Journal of Respiratory and Critical Care Medicine. PMID 26926297 DOI: 10.1164/rccm.201511-2281OC  1
2016 Fu L, Sun X, He W, Cai C, Onishi A, Zhang F, Linhardt RJ, Liu Z. Keratan sulfate glycosaminoglycan from chicken egg white. Glycobiology. PMID 26903438 DOI: 10.1093/glycob/cww017  1
2016 Zheng Y, Miao J, Zhang F, Cai C, Koh A, Simmons TJ, Mousa SA, Linhardt RJ. Surface modification of a polyethylene film for anticoagulant and anti-microbial catheter. Reactive & Functional Polymers. 100: 142-150. PMID 26900340 DOI: 10.1016/j.reactfunctpolym.2016.01.013  1
2016 Fox JC, Tyler RC, Peterson FC, Dyer DP, Zhang F, Linhardt RJ, Handel TM, Volkman BF. Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer. Biochemistry. PMID 26836755 DOI: 10.1021/acs.biochem.5b01329  1
2016 Zheng Y, Cai C, Zhang F, Monty J, Linhardt RJ, Simmons TJ. Can natural fibers be a silver bullet? Antibacterial cellulose fibers through the covalent bonding of silver nanoparticles to electrospun fibers. Nanotechnology. 27: 055102. PMID 26751520 DOI: 10.1088/0957-4484/27/5/055102  1
2016 Ouyang Y, Wu C, Sun X, Liu J, Linhardt RJ, Zhang Z. Development of hydrophilic interaction chromatography with quadruple time-of-flight mass spectrometry for heparin and low molecular weight heparin disaccharide analysis. Rapid Communications in Mass Spectrometry : Rcm. 30: 277-84. PMID 26689158 DOI: 10.1002/rcm.7437  1
2016 Zheng Y, Miao J, Zhang F, Cai C, Koh A, Simmons TJ, Mousa SA, Linhardt RJ. Surface modification of a polyethylene film for anticoagulant and antimicrobial catheter Reactive and Functional Polymers. 100: 142-150. DOI: 10.1016/j.reactfunctpolym.2016.01.013  1
2015 Sun X, Lin L, Liu X, Zhang F, Chi L, Xia Q, Linhardt RJ. Capillary Electrophoresis-Mass Spectrometry for the Analysis of Heparin Oligosaccharides and Low Molecular Weight Heparin. Analytical Chemistry. PMID 26714061 DOI: 10.1021/acs.analchem.5b04405  1
2015 Ucakturk E, Akman O, Sun X, Baydar DE, Dolgun A, Zhang F, Linhardt RJ. Changes in composition and sulfation patterns of glycoaminoglycans in renal cell carcinoma. Glycoconjugate Journal. PMID 26662466 DOI: 10.1007/s10719-015-9643-1  1
2015 Fu L, Suflita M, Linhardt RJ. Bioengineered heparins and heparan sulfates. Advanced Drug Delivery Reviews. PMID 26555370 DOI: 10.1016/j.addr.2015.11.002  1
2015 Yi L, Ouyang Y, Sun X, Xu N, Linhardt RJ, Zhang Z. Qualitative and quantitative analysis of branches in dextran using high-performance anion exchange chromatography coupled to quadrupole time-of-flight mass spectrometry. Journal of Chromatography. A. PMID 26530145 DOI: 10.1016/j.chroma.2015.10.064  1
2015 Cress BF, Trantas EA, Ververidis F, Linhardt RJ, Koffas MA. Sensitive cells: enabling tools for static and dynamic control of microbial metabolic pathways. Current Opinion in Biotechnology. 36: 205-214. PMID 26453934 DOI: 10.1016/j.copbio.2015.09.007  1
2015 Higashi K, Okamoto Y, Mukuno A, Wakai J, Hosoyama S, Linhardt RJ, Toida T. Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue. Carbohydrate Polymers. 134: 557-65. PMID 26428158 DOI: 10.1016/j.carbpol.2015.07.082  1
2015 Su G, Li L, Huang H, Zhong W, Yu P, Zhang F, Linhardt RJ. Production of a low molecular weight heparin production using recombinant glycuronidase. Carbohydrate Polymers. 134: 151-7. PMID 26428111 DOI: 10.1016/j.carbpol.2015.08.001  1
2015 Zhang F, Zhang J, Linhardt RJ. Interactions between nattokinase and heparin/GAGs. Glycoconjugate Journal. PMID 26412225 DOI: 10.1007/s10719-015-9620-8  1
2015 Wang CP, Hascall VC, Zhang F, Linhardt RJ, Abbadi A, Wang A. The responses of hyperglycemic dividing mesangial cells to heparin is mediated by the non-reducing terminal trisaccharide. The Journal of Biological Chemistry. PMID 26378235 DOI: 10.1074/jbc.M115.677401  1
2015 Schaub NJ, Le Beux C, Miao J, Linhardt RJ, Alauzun JG, Laurencin D, Gilbert RJ. The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension. Plos One. 10: e0136780. PMID 26340351 DOI: 10.1371/journal.pone.0136780  1
2015 Kailemia MJ, Patel AB, Johnson DT, Li L, Linhardt RJ, Amster IJ. Differentiating chondroitin sulfate glycosaminoglycans using collision-induced dissociation; uronic acid cross-ring diagnostic fragments in a single stage of tandem mass spectrometry. European Journal of Mass Spectrometry (Chichester, England). 21: 275-85. PMID 26307707 DOI: 10.1255/ejms.1366  1
2015 Ouyang Y, Zeng Y, Rong Y, Song Y, Shi L, Chen B, Yang X, Xu N, Linhardt RJ, Zhang Z. Profiling Analysis of Low Molecular Weight Heparins by Multiple Heart-Cutting Two Dimensional Chromatography with Quadruple Time-of-Flight Mass Spectrometry. Analytical Chemistry. 87: 8957-63. PMID 26222954 DOI: 10.1021/acs.analchem.5b02218  1
2015 Suflita M, Fu L, He W, Koffas M, Linhardt RJ. Heparin and related polysaccharides: synthesis using recombinant enzymes and metabolic engineering. Applied Microbiology and Biotechnology. 99: 7465-79. PMID 26219501 DOI: 10.1007/s00253-015-6821-9  1
2015 Zhang F, Lee KB, Linhardt RJ. SPR Biosensor Probing the Interactions between TIMP-3 and Heparin/GAGs. Biosensors. 5: 500-12. PMID 26213979 DOI: 10.3390/bios5030500  1
2015 Bhaskar U, Hickey AM, Li G, Mundra RV, Zhang F, Fu L, Cai C, Ou Z, Dordick JS, Linhardt RJ. A purification process for heparin and precursor polysaccharides using the pH responsive behavior of chitosan. Biotechnology Progress. PMID 26147064 DOI: 10.1002/btpr.2144  1
2015 Farrán A, Cai C, Sandoval M, Xu Y, Liu J, Hernáiz MJ, Linhardt RJ. Green solvents in carbohydrate chemistry: from raw materials to fine chemicals. Chemical Reviews. 115: 6811-53. PMID 26121409 DOI: 10.1021/cr500719h  1
2015 Zhao Y, Singh A, Li L, Linhardt RJ, Xu Y, Liu J, Woods RJ, Amster IJ. Investigating changes in the gas-phase conformation of Antithrombin III upon binding of Arixtra using traveling wave ion mobility spectrometry (TWIMS). The Analyst. 140: 6980-9. PMID 26115461 DOI: 10.1039/c5an00908a  1
2015 Mora-Pale M, Bhan N, Masuko S, James P, Wood J, McCallum S, Linhardt RJ, Dordick JS, Koffas MA. Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol. Biotechnology and Bioengineering. PMID 26109045 DOI: 10.1002/bit.25686  1
2015 Kwon SJ, Zhang F, Dordick JS, Sonstein WJ, Linhardt RJ. Detection of cerebrospinal fluid leakage by specific measurement of transferrin glycoforms. Electrophoresis. 36: 2425-32. PMID 26084971 DOI: 10.1002/elps.201500128  1
2015 Jones JA, Vernacchio VR, Lachance DM, Lebovich M, Fu L, Shirke AN, Schultz VL, Cress B, Linhardt RJ, Koffas MA. ePathOptimize: A Combinatorial Approach for Transcriptional Balancing of Metabolic Pathways. Scientific Reports. 5: 11301. PMID 26062452 DOI: 10.1038/srep11301  1
2015 Bhan N, Cress BF, Linhardt RJ, Koffas M. Expanding the chemical space of polyketides through structure-guided mutagenesis of Vitis vinifera stilbene synthase. Biochimie. 115: 136-43. PMID 26048582 DOI: 10.1016/j.biochi.2015.05.019  1
2015 Baik JY, Dahodwala H, Oduah E, Talman L, Gemmill TR, Gasimli L, Datta P, Yang B, Li G, Zhang F, Li L, Linhardt RJ, Campbell AM, Gorfien SF, Sharfstein ST. Optimization of bioprocess conditions improves production of a CHO cell-derived, bioengineered heparin. Biotechnology Journal. 10: 1067-81. PMID 26037948 DOI: 10.1002/biot.201400665  1
2015 Sun X, Li L, Overdier KH, Ammons LA, Douglas IS, Burlew CC, Zhang F, Schmidt EP, Chi L, Linhardt RJ. Analysis of Total Human Urinary Glycosaminoglycan Disaccharides by Liquid Chromatography-Tandem Mass Spectrometry. Analytical Chemistry. 87: 6220-7. PMID 26005898 DOI: 10.1021/acs.analchem.5b00913  1
2015 Hayashida A, Amano S, Gallo RL, Linhardt RJ, Liu J, Park PW. 2-O-Sulfated Domains in Syndecan-1 Heparan Sulfate Inhibit Neutrophil Cathelicidin and Promote Staphylococcus aureus Corneal Infection. The Journal of Biological Chemistry. 290: 16157-67. PMID 25931123 DOI: 10.1074/jbc.M115.660852  1
2015 Yi L, Sun X, Du K, Ouyang Y, Wu C, Xu N, Linhardt RJ, Zhang Z. UP-HILIC-MS/MS to Determine the Action Pattern of Penicillium sp. Dextranase. Journal of the American Society For Mass Spectrometry. 26: 1174-85. PMID 25930093 DOI: 10.1007/s13361-015-1117-y  1
2015 Li G, Li L, Xue C, Middleton D, Linhardt RJ, Avci FY. Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography-tandem mass spectrometry. Journal of Chromatography. A. 1397: 43-51. PMID 25913329 DOI: 10.1016/j.chroma.2015.04.009  1
2015 Yang Y, Lin Y, Li L, Linhardt RJ, Yan Y. Regulating malonyl-CoA metabolism via synthetic antisense RNAs for enhanced biosynthesis of natural products. Metabolic Engineering. 29: 217-26. PMID 25863265 DOI: 10.1016/j.ymben.2015.03.018  1
2015 Cress BF, Toparlak ÖD, Guleria S, Lebovich M, Stieglitz JT, Englaender JA, Jones JA, Linhardt RJ, Koffas MA. CRISPathBrick: Modular Combinatorial Assembly of Type II-A CRISPR Arrays for dCas9-Mediated Multiplex Transcriptional Repression in E. coli. Acs Synthetic Biology. 4: 987-1000. PMID 25822415 DOI: 10.1021/acssynbio.5b00012  1
2015 Bhaskar U, Li G, Fu L, Onishi A, Suflita M, Dordick JS, Linhardt RJ. Combinatorial one-pot chemoenzymatic synthesis of heparin. Carbohydrate Polymers. 122: 399-407. PMID 25817684 DOI: 10.1016/j.carbpol.2014.10.054  1
2015 Lu J, Yang H, Hao J, Wu C, Liu L, Xu N, Linhardt RJ, Zhang Z. Impact of hydrolysis conditions on the detection of mannuronic to guluronic acid ratio in alginate and its derivatives. Carbohydrate Polymers. 122: 180-8. PMID 25817657 DOI: 10.1016/j.carbpol.2015.01.008  1
2015 Higashi K, Takeuchi Y, Mukuno A, Tomitori H, Miya M, Linhardt RJ, Toida T. Composition of glycosaminoglycans in elasmobranchs including several deep-sea sharks: identification of chondroitin/dermatan sulfate from the dried fins of Isurus oxyrinchus and Prionace glauca. Plos One. 10: e0120860. PMID 25803296 DOI: 10.1371/journal.pone.0120860  1
2015 Mannello F, Maccari F, Ligi D, Santi M, Gatto F, Linhardt RJ, Galeotti F, Volpi N. Breast cyst fluid heparan sulphate is distinctively N-sulphated depending on apocrine or flattened type. Cell Biochemistry and Function. 33: 128-33. PMID 25753066 DOI: 10.1002/cbf.3096  1
2015 Li Z, Moniz H, Wang S, Ramiah A, Zhang F, Moremen KW, Linhardt RJ, Sharp JS. High structural resolution hydroxyl radical protein footprinting reveals an extended Robo1-heparin binding interface. The Journal of Biological Chemistry. 290: 10729-40. PMID 25752613 DOI: 10.1074/jbc.M115.648410  1
2015 Li G, Li L, Tian F, Zhang L, Xue C, Linhardt RJ. Glycosaminoglycanomics of cultured cells using a rapid and sensitive LC-MS/MS approach. Acs Chemical Biology. 10: 1303-10. PMID 25680304 DOI: 10.1021/acschembio.5b00011  1
2015 Purmessur D, Cornejo MC, Cho SK, Roughley PJ, Linhardt RJ, Hecht AC, Iatridis JC. Intact glycosaminoglycans from intervertebral disc-derived notochordal cell-conditioned media inhibit neurite growth while maintaining neuronal cell viability. The Spine Journal : Official Journal of the North American Spine Society. 15: 1060-9. PMID 25661435 DOI: 10.1016/j.spinee.2015.02.003  1
2015 Zhang J, Suflita M, Li G, Zhong W, Li L, Dordick JS, Linhardt RJ, Zhang F. High cell density cultivation of recombinant Escherichia coli strains expressing 2-O-sulfotransferase and C5-epimerase for the production of bioengineered heparin. Applied Biochemistry and Biotechnology. 175: 2986-95. PMID 25586487 DOI: 10.1007/s12010-014-1466-1  1
2015 Lamkin E, Cheng G, Calabro A, Hascall VC, Joo EJ, Li L, Linhardt RJ, Lauer ME. Heavy chain transfer by tumor necrosis factor-stimulated gene 6 to the bikunin proteoglycan. The Journal of Biological Chemistry. 290: 5156-66. PMID 25561734 DOI: 10.1074/jbc.M114.636258  1
2015 Zheng Y, Monty J, Linhardt RJ. Polysaccharide-based nanocomposites and their applications. Carbohydrate Research. 405: 23-32. PMID 25498200 DOI: 10.1016/j.carres.2014.07.016  1
2015 Dimitrievska S, Cai C, Weyers A, Balestrini JL, Lin T, Sundaram S, Hatachi G, Spiegel DA, Kyriakides TR, Miao J, Li G, Niklason LE, Linhardt RJ. Click-coated, heparinized, decellularized vascular grafts. Acta Biomaterialia. 13: 177-87. PMID 25463496 DOI: 10.1016/j.actbio.2014.11.015  1
2015 He W, Fu L, Li G, Andrew Jones J, Linhardt RJ, Koffas M. Production of chondroitin in metabolically engineered E. coli. Metabolic Engineering. 27: 92-100. PMID 25461828 DOI: 10.1016/j.ymben.2014.11.003  1
2015 Fu L, McCallum SA, Miao J, Hart C, Tudryn GJ, Zhang F, Linhardt RJ. Rapid and accurate determination of the lignin content of lignocellulosic biomass by solid-state NMR. Fuel (London, England). 141: 39-45. PMID 25404762 DOI: 10.1016/j.fuel.2014.10.039  1
2015 Bhan N, Li L, Cai C, Xu P, Linhardt RJ, Koffas MA. Enzymatic formation of a resorcylic acid by creating a structure-guided single-point mutation in stilbene synthase. Protein Science : a Publication of the Protein Society. 24: 167-73. PMID 25402946 DOI: 10.1002/pro.2600  1
2015 Zhang J, Suflita M, Fiaschetti CM, Li G, Li L, Zhang F, Dordick JS, Linhardt RJ. High cell density cultivation of a recombinant Escherichia coli strain expressing a 6-O-sulfotransferase for the production of bioengineered heparin. Journal of Applied Microbiology. 118: 92-8. PMID 25362996 DOI: 10.1111/jam.12684  1
2015 Jasper JP, Zhang F, Poe RB, Linhardt RJ. Stable isotopic analysis of porcine, bovine, and ovine heparins. Journal of Pharmaceutical Sciences. 104: 457-63. PMID 25186630 DOI: 10.1002/jps.24134  1
2015 Datta P, Yang B, Linhardt RJ, Sharfstein ST. Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells. Cytotechnology. 67: 223-35. PMID 24468831 DOI: 10.1007/s10616-013-9677-9  1
2015 Simmons TJ, Vera-Reveles G, González G, Gutiérrez-Hernández JM, Linhardt RJ, Navarro-Contreras H, González FJ. Bolometric properties of semiconducting and metallic single-walled carbon nanotube composite films Acs Photonics. 2: 334-340. DOI: 10.1021/ph500285r  1
2015 Dickinson DM, Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparins Glycoscience: Biology and Medicine. 419-426. DOI: 10.1007/978-4-431-54841-6_42  1
2015 Liu ZG, Wang CD, Hu JL, Zhang FM, Linhardt RJ, Lin XC. Apparent digestibility of diet dominantly comprised of Phyllostachys vivax bamboo shoots for captive giant pandas Journal of Animal and Plant Sciences. 25: 612-617.  1
2014 Zhang F, Liang X, Beaudet JM, Lee Y, Linhardt RJ. The Effects of Metal Ions on Heparin/Heparin Sulfate-Protein Interactions. Journal of Biomedical Technology and Research. 1. PMID 28890953  1
2014 Zhang F, Xie J, Linhardt RJ. Isolation and structural characterization of glycosaminoglycans from heads of red salmon (Oncorhynchus nerka). Jacobs Journal of Biotechnology and Bioengineering. 1: 002. PMID 26918243  1
2014 Warda M, Prince A, Kim HK, Khafaga N, Scholkamy T, Linhardt RJ, Jin H. Proteomics of old world camelid (Camelus dromedarius): Better understanding the interplay between homeostasis and desert environment. Journal of Advanced Research. 5: 219-42. PMID 25685490 DOI: 10.1016/j.jare.2013.03.004  1
2014 Liu Z, Zhang F, Li L, Li G, He W, Linhardt RJ. Compositional analysis and structural elucidation of glycosaminoglycans in chicken eggs. Glycoconjugate Journal. 31: 593-602. PMID 25218438 DOI: 10.1007/s10719-014-9557-3  1
2014 Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparan sulfate and heparin. Natural Product Reports. 31: 1676-85. PMID 25197032 DOI: 10.1039/c4np00076e  1
2014 Fu L, Li L, Cai C, Li G, Zhang F, Linhardt RJ. Heparin stability by determining unsubstituted amino groups using hydrophilic interaction chromatography mass spectrometry. Analytical Biochemistry. 461: 46-8. PMID 24909446 DOI: 10.1016/j.ab.2014.05.028  1
2014 Li G, Steppich J, Wang Z, Sun Y, Xue C, Linhardt RJ, Li L. Bottom-up low molecular weight heparin analysis using liquid chromatography-Fourier transform mass spectrometry for extensive characterization. Analytical Chemistry. 86: 6626-32. PMID 24905078 DOI: 10.1021/ac501301v  1
2014 Aguilera JJ, Zhang F, Beaudet JM, Linhardt RJ, Colón W. Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A. Biochimie. 104: 70-80. PMID 24878279 DOI: 10.1016/j.biochi.2014.05.007  1
2014 Ucakturk E, Cai C, Li L, Li G, Zhang F, Linhardt RJ. Capillary electrophoresis for total glycosaminoglycan analysis. Analytical and Bioanalytical Chemistry. 406: 4617-26. PMID 24817364 DOI: 10.1007/s00216-014-7859-8  1
2014 Meli L, Barbosa HS, Hickey AM, Gasimli L, Nierode G, Diogo MM, Linhardt RJ, Cabral JM, Dordick JS. Three dimensional cellular microarray platform for human neural stem cell differentiation and toxicology. Stem Cell Research. 13: 36-47. PMID 24816401 DOI: 10.1016/j.scr.2014.04.004  1
2014 Zhang F, Moniz HA, Walcott B, Moremen KW, Wang L, Linhardt RJ. Probing the impact of GFP tagging on Robo1-heparin interaction. Glycoconjugate Journal. 31: 299-307. PMID 24748467 DOI: 10.1007/s10719-014-9522-1  1
2014 Liu L, Linhardt RJ, Zhang Z. Quantitative analysis of anions in glycosaminoglycans and application in heparin stability studies. Carbohydrate Polymers. 106: 343-50. PMID 24721088 DOI: 10.1016/j.carbpol.2014.02.076  1
2014 Cai C, Dickinson DM, Li L, Masuko S, Suflita M, Schultz V, Nelson SD, Bhaskar U, Liu J, Linhardt RJ. Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides. Organic Letters. 16: 2240-3. PMID 24697306 DOI: 10.1021/ol500738g  1
2014 Li G, Yang B, Li L, Zhang F, Xue C, Linhardt RJ. Analysis of 3-O-sulfo group-containing heparin tetrasaccharides in heparin by liquid chromatography-mass spectrometry. Analytical Biochemistry. 455: 3-9. PMID 24680753 DOI: 10.1016/j.ab.2014.02.033  1
2014 Fu L, Zhang F, Li G, Onishi A, Bhaskar U, Sun P, Linhardt RJ. Structure and activity of a new low-molecular-weight heparin produced by enzymatic ultrafiltration. Journal of Pharmaceutical Sciences. 103: 1375-83. PMID 24634007 DOI: 10.1002/jps.23939  1
2014 Sterner E, Masuko S, Li G, Li L, Green DE, Otto NJ, Xu Y, DeAngelis PL, Liu J, Dordick JS, Linhardt RJ. Fibroblast growth factor-based signaling through synthetic heparan sulfate blocks copolymers studied using high cell density three-dimensional cell printing. The Journal of Biological Chemistry. 289: 9754-65. PMID 24563485 DOI: 10.1074/jbc.M113.546937  1
2014 Xu Y, Cai C, Chandarajoti K, Hsieh PH, Li L, Pham TQ, Sparkenbaugh EM, Sheng J, Key NS, Pawlinski R, Harris EN, Linhardt RJ, Liu J. Homogeneous low-molecular-weight heparins with reversible anticoagulant activity. Nature Chemical Biology. 10: 248-50. PMID 24561662 DOI: 10.1038/nchembio.1459  1
2014 Schmidt EP, Li G, Li L, Fu L, Yang Y, Overdier KH, Douglas IS, Linhardt RJ. The circulating glycosaminoglycan signature of respiratory failure in critically ill adults. The Journal of Biological Chemistry. 289: 8194-202. PMID 24509853 DOI: 10.1074/jbc.M113.539452  1
2014 Maeda N, Miao J, Simmons TJ, Dordick JS, Linhardt RJ. Composite polysaccharide fibers prepared by electrospinning and coating. Carbohydrate Polymers. 102: 950-5. PMID 24507368 DOI: 10.1016/j.carbpol.2013.10.038  1
2014 Kwon SJ, Jeong EJ, Yoo YC, Cai C, Yang GH, Lee JC, Dordick JS, Linhardt RJ, Lee KB. High sensitivity detection of active botulinum neurotoxin by glyco-quantitative polymerase chain-reaction. Analytical Chemistry. 86: 2279-84. PMID 24506443 DOI: 10.1021/ac500262d  1
2014 Volpi N, Galeotti F, Yang B, Linhardt RJ. Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone-labeled disaccharides with LC-fluorescence and LC-MS detection. Nature Protocols. 9: 541-58. PMID 24504479 DOI: 10.1038/nprot.2014.026  1
2014 Joo EJ, Weyers A, Li G, Gasimli L, Li L, Choi WJ, Lee KB, Linhardt RJ. Carbohydrate-containing molecules as potential biomarkers in colon cancer. Omics : a Journal of Integrative Biology. 18: 231-41. PMID 24502776 DOI: 10.1089/omi.2013.0128  1
2014 Fulcher YG, Sanganna Gari RR, Frey NC, Zhang F, Linhardt RJ, King GM, Van Doren SR. Heparinoids activate a protease, secreted by mucosa and tumors, via tethering supplemented by allostery. Acs Chemical Biology. 9: 957-66. PMID 24495220 DOI: 10.1021/cb400898t  1
2014 Mora-Pale M, Sanchez-Rodriguez SP, Linhardt RJ, Dordick JS, Koffas MA. Biochemical strategies for enhancing the in vivo production of natural products with pharmaceutical potential. Current Opinion in Biotechnology. 25: 86-94. PMID 24484885 DOI: 10.1016/j.copbio.2013.09.009  1
2014 Gasimli L, Hickey AM, Yang B, Li G, dela Rosa M, Nairn AV, Kulik MJ, Dordick JS, Moremen KW, Dalton S, Linhardt RJ. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages. Biochimica Et Biophysica Acta. 1840: 1993-2003. PMID 24412195 DOI: 10.1016/j.bbagen.2014.01.007  1
2014 Cress BF, Englaender JA, He W, Kasper D, Linhardt RJ, Koffas MA. Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules. Fems Microbiology Reviews. 38: 660-97. PMID 24372337 DOI: 10.1111/1574-6976.12056  1
2014 Li G, Cai C, Li L, Fu L, Chang Y, Zhang F, Toida T, Xue C, Linhardt RJ. Method to detect contaminants in heparin using radical depolymerization and liquid chromatography-mass spectrometry. Analytical Chemistry. 86: 326-30. PMID 24364596 DOI: 10.1021/ac403625a  1
2014 Zhang B, Xiao W, Qiu H, Zhang F, Moniz HA, Jaworski A, Condac E, Gutierrez-Sanchez G, Heiss C, Clugston RD, Azadi P, Greer JJ, Bergmann C, Moremen KW, Li D, ... Linhardt RJ, et al. Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia. The Journal of Clinical Investigation. 124: 209-21. PMID 24355925 DOI: 10.1172/JCI71090  1
2014 Gasimli L, Glass CA, Datta P, Yang B, Li G, Gemmill TR, Baik JY, Sharfstein ST, Esko JD, Linhardt RJ. Bioengineering murine mastocytoma cells to produce anticoagulant heparin. Glycobiology. 24: 272-80. PMID 24326668 DOI: 10.1093/glycob/cwt108  1
2014 Sterner E, Li L, Paul P, Beaudet JM, Liu J, Linhardt RJ, Dordick JS. Assays for determining heparan sulfate and heparin O-sulfotransferase activity and specificity. Analytical and Bioanalytical Chemistry. 406: 525-36. PMID 24271188 DOI: 10.1007/s00216-013-7470-4  1
2014 Kailemia MJ, Park M, Kaplan DA, Venot A, Boons GJ, Li L, Linhardt RJ, Amster IJ. High-field asymmetric-waveform ion mobility spectrometry and electron detachment dissociation of isobaric mixtures of glycosaminoglycans. Journal of the American Society For Mass Spectrometry. 25: 258-68. PMID 24254578 DOI: 10.1007/s13361-013-0771-1  1
2014 Datta P, Meli L, Li L, Migliore N, Schaefer E, Sharfstein ST, Dordick JS, Linhardt RJ. Microarray platform affords improved product analysis in mammalian cell growth studies. Biotechnology Journal. 9: 386-95. PMID 24227746 DOI: 10.1002/biot.201300288  1
2014 Huang H, Zhao Y, Lv S, Zhong W, Zhang F, Linhardt RJ. Quantitation of heparosan with heparin lyase III and spectrophotometry. Analytical Biochemistry. 447: 46-8. PMID 24184357 DOI: 10.1016/j.ab.2013.10.029  1
2014 Beaudet JM, Mansur L, Joo EJ, Kamhi E, Yang B, Clausen TM, Salanti A, Zhang F, Linhardt RJ. Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes. Glycoconjugate Journal. 31: 109-16. PMID 24158546 DOI: 10.1007/s10719-013-9506-6  1
2014 Zheng Y, Miao J, Maeda N, Frey D, Linhardt RJ, Simmons TJ. Uniform nanoparticle coating of cellulose fibers during wet electrospinning Journal of Materials Chemistry A. 2: 15029-15034. DOI: 10.1039/c4ta03221g  1
2013 Sterner E, Meli L, Kwon SJ, Dordick JS, Linhardt RJ. FGF-FGFR signaling mediated through glycosaminoglycans in microtiter plate and cell-based microarray platforms. Biochemistry. 52: 9009-19. PMID 24289246 DOI: 10.1021/bi401284r  1
2013 Datta P, Li G, Yang B, Zhao X, Baik JY, Gemmill TR, Sharfstein ST, Linhardt RJ. Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site. The Journal of Biological Chemistry. 288: 37308-18. PMID 24247246 DOI: 10.1074/jbc.M113.519033  1
2013 Zhang F, Moniz HA, Walcott B, Moremen KW, Linhardt RJ, Wang L. Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans. Biochimie. 95: 2345-53. PMID 23994753 DOI: 10.1016/j.biochi.2013.08.018  1
2013 Chang Y, Cai C, Li L, Miao J, Ucakturk E, Li G, Ly M, Linhardt RJ. Ultrasensitive detection and quantification of acidic disaccharides using capillary electrophoresis and quantum dot-based fluorescence resonance energy transfer. Analytical Chemistry. 85: 9356-62. PMID 23985015 DOI: 10.1021/ac402242v  1
2013 Zhang F, Aguilera J, Beaudet JM, Xie Q, Lerch TF, Davulcu O, Colón W, Chapman MS, Linhardt RJ. Characterization of interactions between heparin/glycosaminoglycan and adeno-associated virus. Biochemistry. 52: 6275-85. PMID 23952613 DOI: 10.1021/bi4008676  1
2013 Cai C, Li L, Harvey C, Liu J, Linhardt RJ. Towards the chemoenzymatic synthesis of heparan sulfate oligosaccharides: Oxidative cleavage of p-nitrophenyl group with ceric ammonium salts. Tetrahedron Letters. 54: 4471-4474. PMID 23929984 DOI: 10.1016/j.tetlet.2013.06.044  1
2013 Wang W, Englaender JA, Xu P, Mehta KK, Suwan J, Dordick JS, Zhang F, Yuan Q, Linhardt RJ, Koffas M. Expression of low endotoxin 3-O-sulfotransferase in Bacillus subtilis and Bacillus megaterium. Applied Biochemistry and Biotechnology. 171: 954-62. PMID 23912211 DOI: 10.1007/s12010-013-0415-8  1
2013 Nicastri MC, Xega K, Li L, Xie J, Wang C, Linhardt RJ, Reitter JN, Mills KV. Internal disulfide bond acts as a switch for intein activity. Biochemistry. 52: 5920-7. PMID 23906287 DOI: 10.1021/bi400736c  1
2013 Nolan K, Kattamuri C, Luedeke DM, Deng X, Jagpal A, Zhang F, Linhardt RJ, Kenny AP, Zorn AM, Thompson TB. Structure of protein related to Dan and Cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure (London, England : 1993). 21: 1417-29. PMID 23850456 DOI: 10.1016/j.str.2013.06.005  1
2013 Mora-Pale M, Sanchez-Rodriguez SP, Linhardt RJ, Dordick JS, Koffas MA. Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues. Plant Science : An International Journal of Experimental Plant Biology. 210: 10-24. PMID 23849109 DOI: 10.1016/j.plantsci.2013.05.005  1
2013 Xiong J, Bhaskar U, Li G, Fu L, Li L, Zhang F, Dordick JS, Linhardt RJ. Immobilized enzymes to convert N-sulfo, N-acetyl heparosan to a critical intermediate in the production of bioengineered heparin. Journal of Biotechnology. 167: 241-7. PMID 23835156 DOI: 10.1016/j.jbiotec.2013.06.018  1
2013 Zhao X, Yang B, Li L, Zhang F, Linhardt RJ. On-line separation and characterization of hyaluronan oligosaccharides derived from radical depolymerization. Carbohydrate Polymers. 96: 503-9. PMID 23768593 DOI: 10.1016/j.carbpol.2013.04.009  1
2013 Li G, Masuko S, Green DE, Xu Y, Li L, Zhang F, Xue C, Liu J, Deangelis PL, Linhardt RJ. N-sulfotestosteronan, a novel substrate for heparan sulfate 6-o-sulfotransferases and its analysis by oxidative degradation. Biopolymers. 99: 675-85. PMID 23606289 DOI: 10.1002/bip.22263  1
2013 Weyers A, Yang B, Park JH, Kim YS, Kim SM, Lee SE, Zhang F, Lee KB, Linhardt RJ. Microanalysis of stomach cancer glycosaminoglycans. Glycoconjugate Journal. 30: 701-7. PMID 23604988 DOI: 10.1007/s10719-013-9476-8  1
2013 Hickey AM, Bhaskar U, Linhardt RJ, Dordick JS. Effect of eliminase gene (elmA) deletion on heparosan production and shedding in Escherichia coli K5. Journal of Biotechnology. 165: 175-7. PMID 23583654 DOI: 10.1016/j.jbiotec.2013.03.018  1
2013 Kamhi E, Joo EJ, Dordick JS, Linhardt RJ. Glycosaminoglycans in infectious disease. Biological Reviews of the Cambridge Philosophical Society. 88: 928-43. PMID 23551941 DOI: 10.1111/brv.12034  1
2013 Karamanos NK, Linhardt RJ. Special issue: Proteoglycans: signaling, targeting and therapeutics: introduction. The Febs Journal. 280: 2119. PMID 23530537 DOI: 10.1111/febs.12262  1
2013 Fu L, Li G, Yang B, Onishi A, Li L, Sun P, Zhang F, Linhardt RJ. Structural characterization of pharmaceutical heparins prepared from different animal tissues. Journal of Pharmaceutical Sciences. 102: 1447-57. PMID 23526651 DOI: 10.1002/jps.23501  1
2013 Cai C, Edgar K, Liu J, Linhardt RJ. Preparation and application of a 'clickable' acceptor for enzymatic synthesis of heparin oligosaccharides. Carbohydrate Research. 372: 30-4. PMID 23524108 DOI: 10.1016/j.carres.2013.02.010  1
2013 Cress BF, Greene ZR, Linhardt RJ, Koffas MA. Draft Genome Sequence of Escherichia coli Strain ATCC 23506 (Serovar O10:K5:H4). Genome Announcements. 1: e0004913. PMID 23516192 DOI: 10.1128/genomeA.00049-13  1
2013 Cress BF, Linhardt RJ, Koffas MA. Draft Genome Sequence of Escherichia coli Strain Nissle 1917 (Serovar O6:K5:H1). Genome Announcements. 1: e0004713. PMID 23516190 DOI: 10.1128/genomeA.00047-13  1
2013 Cress BF, Greene ZR, Linhardt RJ, Koffas MA. Draft Genome Sequence of Escherichia coli Strain ATCC 23502 (Serovar O5:K4:H4). Genome Announcements. 1: e0004613. PMID 23516189 DOI: 10.1128/genomeA.00046-13  1
2013 DeAngelis PL, Liu J, Linhardt RJ. Chemoenzymatic synthesis of glycosaminoglycans: re-creating, re-modeling and re-designing nature's longest or most complex carbohydrate chains. Glycobiology. 23: 764-77. PMID 23481097 DOI: 10.1093/glycob/cwt016  1
2013 Zhang F, Walcott B, Zhou D, Gustchina A, Lasanajak Y, Smith DF, Ferreira RS, Correia MT, Paiva PM, Bovin NV, Wlodawer A, Oliva ML, Linhardt RJ. Structural studies of the interaction of Crataeva tapia bark protein with heparin and other glycosaminoglycans. Biochemistry. 52: 2148-56. PMID 23448527 DOI: 10.1021/bi400077b  1
2013 Kailemia MJ, Li L, Xu Y, Liu J, Linhardt RJ, Amster IJ. Structurally informative tandem mass spectrometry of highly sulfated natural and chemoenzymatically synthesized heparin and heparan sulfate glycosaminoglycans. Molecular & Cellular Proteomics : McP. 12: 979-90. PMID 23429520 DOI: 10.1074/mcp.M112.026880  1
2013 Zhao X, Yang B, Solakyildirim K, Solakylidirim K, Joo EJ, Toida T, Higashi K, Linhardt RJ, Li L. Sequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain. The Journal of Biological Chemistry. 288: 9226-37. PMID 23423381 DOI: 10.1074/jbc.M112.437236  1
2013 Weyers A, Yang B, Solakyildirim K, Yee V, Li L, Zhang F, Linhardt RJ. Isolation of bovine corneal keratan sulfate and its growth factor and morphogen binding Febs Journal. 280: 2285-2293. PMID 23402351 DOI: 10.1111/febs.12165  1
2013 Weyers A, Linhardt RJ. Neoproteoglycans in tissue engineering Febs Journal. 280: 2511-2522. PMID 23399318 DOI: 10.1111/febs.12187  1
2013 Chang Y, Yang B, Weyers A, Linhardt RJ. Capillary electrophoresis for the analysis of glycosaminoglycan-derived disaccharides. Methods in Molecular Biology (Clifton, N.J.). 984: 67-77. PMID 23386338 DOI: 10.1007/978-1-62703-296-4_7  1
2013 Kotlo K, Bhattacharyya S, Yang B, Feferman L, Tejaskumar S, Linhardt R, Danziger R, Tobacman JK. Impact of salt exposure on N-acetylgalactosamine-4-sulfatase (arylsulfatase B) activity, glycosaminoglycans, kininogen, and bradykinin. Glycoconjugate Journal. 30: 667-76. PMID 23385884 DOI: 10.1007/s10719-013-9468-8  1
2013 Zhou X, Li L, Linhardt RJ, Liu J. Neutralizing the anticoagulant activity of ultra-low-molecular-weight heparins using N-acetylglucosamine 6-sulfatase Febs Journal. 280: 2523-2532. PMID 23374371 DOI: 10.1111/febs.12169  1
2013 Datta P, Linhardt RJ, Sharfstein ST. An 'omics approach towards CHO cell engineering. Biotechnology and Bioengineering. 110: 1255-71. PMID 23322664 DOI: 10.1002/bit.24841  1
2013 Restaino OF, Bhaskar U, Paul P, Li L, De Rosa M, Dordick JS, Linhardt RJ. High cell density cultivation of a recombinant E. coli strain expressing a key enzyme in bioengineered heparin production. Applied Microbiology and Biotechnology. 97: 3893-900. PMID 23318839 DOI: 10.1007/s00253-012-4682-z  1
2013 Zhao X, Yang B, Linkens K, Datta P, Onishi A, Zhang F, Linhardt RJ. Microscale separation of heparosan, heparan sulfate, and heparin. Analytical Biochemistry. 434: 215-7. PMID 23262074 DOI: 10.1016/j.ab.2012.12.009  1
2013 Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, Liang X, Su J, Baker JE, Linhardt RJ, Volkman BF. Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus. The Journal of Biological Chemistry. 288: 737-46. PMID 23148226 DOI: 10.1074/jbc.M112.394064  1
2013 Gasimli L, Stansfield HE, Nairn AV, Liu H, Paluh JL, Yang B, Dordick JS, Moremen KW, Linhardt RJ. Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells Glycoconjugate Journal. 30: 497-510. PMID 23053635 DOI: 10.1007/s10719-012-9450-x  1
2013 Simmons TJ, Maeda N, Miyauchi M, Miao J, Hashim DP, Ajayan PM, Dordick JS, Linhardt RJ. Effect of a variety of carbon nanotubes on the iodine-iodide redox pair Carbon. 62: 177-181. DOI: 10.1016/j.carbon.2013.06.009  1
2013 Simmons TJ, Maeda N, Miao J, Bravo-Sanchez M, Dordick JS, Linhardt RJ. Self-assembly of carbon nanotube films from room temperature ionic liquids Carbon. 58: 226-231. DOI: 10.1016/j.carbon.2013.02.062  1
2013 Webster M, Miao J, Lynch B, Green D, Jones-Sawyer R, Linhardt RJ, Mendenhall J. Tunable thermo-responsive poly(N-vinylcaprolactam) cellulose nanofibers: Synthesis, characterization, and fabrication Macromolecular Materials and Engineering. 298: 447-453. DOI: 10.1002/mame.201200081  1
2013 Li G, Masuko S, Green DE, Xu Y, Li L, Zhang F, Xue C, Liu J, Deangelis PL, Linhardt RJ. N-sulfotestosteronan, A novel substrate for heparan sulfate 6-O-sulfotransferases and its analysis by oxidative degradation Biopolymers. 99: 675-685. DOI: 10.1002/bip.22263  1
2013 Hassan HHAM, Elhusseiny AF, Sweyllam AM, Linhardt RJ. New sulfonated aramide nanoparticles and their copper complexes with anomalous dielectric behavior Journal of Applied Polymer Science. 128: 310-321. DOI: 10.1002/app.36791  1
2013 Bhaskar U, Yang B, Fu L, Takieddin M, Zhang F, Mousa SA, Liu J, Dordick JS, Linhardt RJ. Chemoenzymatic synthesis of heparin for a safer bioengineered alternative Pharmaceutical Discovery, Development and Manufacturing Forum 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 183.  1
2013 Bhan N, Mora-Pale M, Koffas MAG, Linhardt RJ, Dordick JS, Masuko S. Generation of resveratrol analogues by enzymatic oligomerization and protein engineering Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 512.  1
2013 Cress B, Linhardt RJ, Koffas MAG. Development of anti-capsular polysaccharide aptamers for high-throughput screening and serotyping Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 239.  1
2013 Mora-Pale M, Bhan N, Masuko S, Linhardt RJ, Koffas MAG, Dordick JS. Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from the enzymatic oligomerization of resveratrol mediated by soybean peroxidase Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 345.  1
2012 Zhao X, Yang B, Datta P, Gasmili L, Zhang F, Linhardt RJ. Cell-Based Microscale Isolation of Glycoaminoglycans for Glycomics Study. Journal of Carbohydrate Chemistry. 31: 420-435. PMID 24068855 DOI: 10.1080/07328303.2012.658126  1
2012 Suwan J, Torelli A, Onishi A, Dordick JS, Linhardt RJ. Addressing endotoxin issues in bioengineered heparin. Biotechnology and Applied Biochemistry. 59: 420-8. PMID 23586950 DOI: 10.1002/bab.1042  1
2012 Gasimli L, Linhardt RJ, Dordick JS. Proteoglycans in stem cells. Biotechnology and Applied Biochemistry. 59: 65-76. PMID 23586787 DOI: 10.1002/bab.1002  1
2012 Wang Z, Zhang F, Dordick JS, Linhardt RJ. Molecular Mass Characterization of Glycosaminoglycans with Different Degrees of Sulfation in Bioengineered Heparin Process by Size Exclusion Chromatography. Current Analytical Chemistry. 8: 506-511. PMID 23258975 DOI: 10.2174/157341112803216753  1
2012 Kwon SJ, Lee KB, Solakyildirim K, Masuko S, Ly M, Zhang F, Li L, Dordick JS, Linhardt RJ. Signal amplification by glyco-qPCR for ultrasensitive detection of carbohydrates: applications in glycobiology. Angewandte Chemie (International Ed. in English). 51: 11800-4. PMID 23073897 DOI: 10.1002/anie.201205112  1
2012 Meli L, Jordan ET, Clark DS, Linhardt RJ, Dordick JS. Influence of a three-dimensional, microarray environment on human cell culture in drug screening systems. Biomaterials. 33: 9087-96. PMID 22998815 DOI: 10.1016/j.biomaterials.2012.08.065  1
2012 Li L, Zhang F, Zaia J, Linhardt RJ. Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS. Analytical Chemistry. 84: 8822-9. PMID 22985071 DOI: 10.1021/ac302232c  1
2012 Leach FE, Ly M, Laremore TN, Wolff JJ, Perlow J, Linhardt RJ, Amster IJ. Hexuronic acid stereochemistry determination in chondroitin sulfate glycosaminoglycan oligosaccharides by electron detachment dissociation. Journal of the American Society For Mass Spectrometry. 23: 1488-97. PMID 22825742 DOI: 10.1007/s13361-012-0428-5  1
2012 Simmons TJ, Hashim DP, Zhan X, Bravo-Sanchez M, Hahm MG, López-Luna E, Linhardt RJ, Ajayan PM, Navarro-Contreras H, Vidal MA. Functionalization of nitrogen-doped carbon nanotubes with gallium to form Ga-CN(x)-multi-wall carbon nanotube hybrid materials. Nanotechnology. 23: 325601. PMID 22825368 DOI: 10.1088/0957-4484/23/32/325601  1
2012 Zhang F, Beaudet JM, Luedeke DM, Walker RG, Thompson TB, Linhardt RJ. Analysis of the interaction between heparin and follistatin and heparin and follistatin-ligand complexes using surface plasmon resonance. Biochemistry. 51: 6797-803. PMID 22809401 DOI: 10.1021/bi300804g  1
2012 Miao J, Miyauchi M, Dordick JS, Linhardt RJ. Preparation and characterization of electrospun core sheath nanofibers from multi-walled carbon nanotubes and poly(vinyl pyrrolidone). Journal of Nanoscience and Nanotechnology. 12: 2387-93. PMID 22755063 DOI: 10.1166/jnn.2012.5710  1
2012 Volpi N, Maccari F, Suwan J, Linhardt RJ. Electrophoresis for the analysis of heparin purity and quality. Electrophoresis. 33: 1531-7. PMID 22736353 DOI: 10.1002/elps.201100479  1
2012 Kailemia MJ, Li L, Ly M, Linhardt RJ, Amster IJ. Complete mass spectral characterization of a synthetic ultralow-molecular-weight heparin using collision-induced dissociation. Analytical Chemistry. 84: 5475-8. PMID 22715938 DOI: 10.1021/ac3015824  1
2012 Baik JY, Wang CL, Yang B, Linhardt RJ, Sharfstein S. Toward a bioengineered heparin: challenges and strategies for metabolic engineering of mammalian cells. Bioengineered. 3: 227-31. PMID 22714556 DOI: 10.4161/bioe.20902  1
2012 Chang Y, Yang B, Zhao X, Linhardt RJ. Analysis of glycosaminoglycan-derived disaccharides by capillary electrophoresis using laser-induced fluorescence detection. Analytical Biochemistry. 427: 91-8. PMID 22609076 DOI: 10.1016/j.ab.2012.05.004  1
2012 Paul P, Suwan J, Liu J, Dordick JS, Linhardt RJ. Recent advances in sulfotransferase enzyme activity assays. Analytical and Bioanalytical Chemistry. 403: 1491-500. PMID 22526635 DOI: 10.1007/s00216-012-5944-4  1
2012 Li L, Ly M, Linhardt RJ. Proteoglycan sequence. Molecular Biosystems. 8: 1613-25. PMID 22513887 DOI: 10.1039/c2mb25021g  1
2012 Moon AF, Xu Y, Woody SM, Krahn JM, Linhardt RJ, Liu J, Pedersen LC. Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin. Proceedings of the National Academy of Sciences of the United States of America. 109: 5265-70. PMID 22431632 DOI: 10.1073/pnas.1117923109  1
2012 Sudha T, Phillips P, Kanaan C, Linhardt RJ, Borsig L, Mousa SA. Inhibitory effect of non-anticoagulant heparin (S-NACH) on pancreatic cancer cell adhesion and metastasis in human umbilical cord vessel segment and in mouse model. Clinical & Experimental Metastasis. 29: 431-9. PMID 22415710 DOI: 10.1007/s10585-012-9461-9  1
2012 Weyers A, Yang B, Yoon DS, Park JH, Zhang F, Lee KB, Linhardt RJ. A structural analysis of glycosaminoglycans from lethal and nonlethal breast cancer tissues: toward a novel class of theragnostics for personalized medicine in oncology? Omics : a Journal of Integrative Biology. 16: 79-89. PMID 22401653 DOI: 10.1089/omi.2011.0102  1
2012 Masuko S, Linhardt RJ. Chemoenzymatic synthesis of the next generation of ultralow MW heparin therapeutics. Future Medicinal Chemistry. 4: 289-96. PMID 22393937 DOI: 10.4155/fmc.11.185  1
2012 Baik JY, Gasimli L, Yang B, Datta P, Zhang F, Glass CA, Esko JD, Linhardt RJ, Sharfstein ST. Metabolic engineering of Chinese hamster ovary cells: towards a bioengineered heparin. Metabolic Engineering. 14: 81-90. PMID 22326251 DOI: 10.1016/j.ymben.2012.01.008  1
2012 Linhardt RJ, Liu J. Synthetic heparin. Current Opinion in Pharmacology. 12: 217-9. PMID 22325855 DOI: 10.1016/j.coph.2011.12.002  1
2012 Miao J, Zhang F, Takieddin M, Mousa S, Linhardt RJ. Adsorption of doxorubicin on poly(methyl methacrylate)-chitosan-heparin-coated activated carbon beads. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 4396-403. PMID 22313019 DOI: 10.1021/la3000137  1
2012 Chen W, Li L, Du Z, Liu J, Reitter JN, Mills KV, Linhardt RJ, Wang C. Intramolecular disulfide bond between catalytic cysteines in an intein precursor. Journal of the American Chemical Society. 134: 2500-3. PMID 22280304 DOI: 10.1021/ja211010g  1
2012 Mora-Pale M, Kwon SJ, Linhardt RJ, Dordick JS. Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase. Free Radical Biology & Medicine. 52: 962-9. PMID 22240153 DOI: 10.1016/j.freeradbiomed.2011.12.015  1
2012 Masuko S, Bera S, Green DE, Weïwer M, Liu J, Deangelis PL, Linhardt RJ. Chemoenzymatic synthesis of uridine diphosphate-GlcNAc and uridine diphosphate-GalNAc analogs for the preparation of unnatural glycosaminoglycans Journal of Organic Chemistry. 77: 1449-1456. PMID 22239739 DOI: 10.1021/jo202322k  1
2012 Yang B, Chang Y, Weyers AM, Sterner E, Linhardt RJ. Disaccharide analysis of glycosaminoglycan mixtures by ultra-high-performance liquid chromatography-mass spectrometry. Journal of Chromatography. A. 1225: 91-8. PMID 22236563 DOI: 10.1016/j.chroma.2011.12.063  1
2012 Otto NJ, Green DE, Masuko S, Mayer A, Tanner ME, Linhardt RJ, DeAngelis PL. Structure/function analysis of Pasteurella multocida heparosan synthases: Toward defining enzyme specificity and engineering novel catalysts Journal of Biological Chemistry. 287: 7203-7212. PMID 22235128 DOI: 10.1074/jbc.M111.311704  1
2012 Higashi K, Hosoyama S, Ohno A, Masuko S, Yang B, Sterner E, Wang Z, Linhardt RJ, Toida T. Photochemical Preparation of a Novel Low Molecular Weight Heparin. Carbohydrate Polymers. 67: 1737-1743. PMID 22205826 DOI: 10.1016/j.carbpol.2011.09.087  1
2012 Cai C, Solakyildirim K, Yang B, Beaudet JM, Weyer A, Linhardt RJ, Zhang F. Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A. Carbohydrate Polymers. 87: 822-829. PMID 22140285 DOI: 10.1016/j.carbpol.2011.08.075  1
2012 Zhang F, Liang X, Pu D, George KI, Holland PJ, Walsh ST, Linhardt RJ. Biophysical characterization of glycosaminoglycan-IL-7 interactions using SPR. Biochimie. 94: 242-9. PMID 22085638 DOI: 10.1016/j.biochi.2011.10.015  1
2012 Bhaskar U, Sterner E, Hickey AM, Onishi A, Zhang F, Dordick JS, Linhardt RJ. Engineering of routes to heparin and related polysaccharides. Applied Microbiology and Biotechnology. 93: 1-16. PMID 22048616 DOI: 10.1007/s00253-011-3641-4  1
2012 Zhao W, McCallum SA, Xiao Z, Zhang F, Linhardt RJ. Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides. Bioscience Reports. 32: 71-81. PMID 21658003 DOI: 10.1042/BSR20110077  1
2012 Wang Z, Nelson JK, Miao J, Linhardt RJ, Schadler LS, Hillborg H, Zhao S. Effect of high aspect ratio filler on dielectric properties of polymer composites: A study on barium titanate fibers and graphene platelets Ieee Transactions On Dielectrics and Electrical Insulation. 19: 960-967. DOI: 10.1109/TDEI.2012.6215100  1
2012 Simmons TJ, Rivet CJ, Singh G, Beaudet J, Sterner E, Guzman D, Hashim DP, Lee SH, Qian G, Lewis KM, Karande P, Ajayan PM, Gilbert RJ, Dordick JS, Linhardt RJ. Application of carbon nanotubes to wound healing biotechnology Acs Symposium Series. 1119: 155-174. DOI: 10.1021/bk-2012-1119.ch007  1
2011 Leach FE, Xiao Z, Laremore TN, Linhardt RJ, Amster IJ. ELECTRON DETACHMENT DISSOCIATION AND INFRARED MULTIPHOTON DISSOCIATION OF HEPARIN TETRASACCHARIDES. International Journal of Mass Spectrometry. 308: 253-259. PMID 22247649 DOI: 10.1016/j.ijms.2011.08.029  1
2011 Vongchan P, Kothan S, Wutti-In Y, Linhardt RJ. Inhibition of human tumor xenograft growth in nude mice by a novel monoclonal anti-HSPG isolated from human liver Anticancer Research. 31: 4067-4074. PMID 22199263  1
2011 Xu Y, Masuko S, Takieddin M, Xu H, Liu R, Jing J, Mousa SA, Linhardt RJ, Liu J. Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins. Science (New York, N.Y.). 334: 498-501. PMID 22034431 DOI: 10.1126/science.1207478  1
2011 Ly M, Leach FE, Laremore TN, Toida T, Amster IJ, Linhardt RJ. The proteoglycan bikunin has a defined sequence. Nature Chemical Biology. 7: 827-33. PMID 21983600 DOI: 10.1038/nchembio.673  1
2011 Miao J, Pangule RC, Paskaleva EE, Hwang EE, Kane RS, Linhardt RJ, Dordick JS. Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications. Biomaterials. 32: 9557-67. PMID 21959009 DOI: 10.1016/j.biomaterials.2011.08.080  1
2011 Zhang F, Yang B, Ly M, Solakyildirim K, Xiao Z, Wang Z, Beaudet JM, Torelli AY, Dordick JS, Linhardt RJ. Structural characterization of heparins from different commercial sources. Analytical and Bioanalytical Chemistry. 401: 2793-803. PMID 21931955 DOI: 10.1007/s00216-011-5367-7  1
2011 Wang Z, Li J, Cheong S, Bhaskar U, Akihiro O, Zhang F, Dordick JS, Linhardt RJ. Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin. Journal of Biotechnology. 156: 188-96. PMID 21925548 DOI: 10.1016/j.jbiotec.2011.08.013  1
2011 Park Y, Hong YN, Weyers A, Kim YS, Linhardt RJ. Polysaccharides and phytochemicals: A natural reservoir for the green synthesis of gold and silver nanoparticles Iet Nanobiotechnology. 5: 69-78. PMID 21913788 DOI: 10.1049/iet-nbt.2010.0033  1
2011 Laremore TN, Leach FE, Amster IJ, Linhardt RJ. Electrospray ionization Fourier transform mass spectrometric analysis of intact bikunin glycosaminoglycan from normal human plasma. International Journal of Mass Spectrometry. 305: 109-115. PMID 21860600 DOI: 10.1016/j.ijms.2010.09.020  1
2011 Higashi K, Ly M, Wang Z, Masuko S, Bhaskar U, Sterner E, Zhang F, Toida T, Dordick JS, Linhardt RJ. Controlled Photochemical Depolymerization of K5 Heparosan, a Bioengineered Heparin Precursor. Carbohydrate Polymers. 86: 1365-1370. PMID 21841848 DOI: 10.1016/j.carbpol.2011.06.042  1
2011 Garg HG, Mrabat H, Yu L, Hales CA, Li B, Moore CN, Zhang F, Linhardt RJ. Anti-proliferative effects of O-acyl-low-molecular-weight heparin derivatives on bovine pulmonary artery smooth muscle cells. Glycoconjugate Journal. 28: 419-26. PMID 21773727 DOI: 10.1007/s10719-011-9341-6  1
2011 Wu H, Mora-Pale M, Miao J, Doherty TV, Linhardt RJ, Dordick JS. Facile pretreatment of lignocellulosic biomass at high loadings in room temperature ionic liquids. Biotechnology and Bioengineering. 108: 2865-75. PMID 21769858 DOI: 10.1002/bit.23266  1
2011 Masuko S, Higashi K, Wang Z, Bhaskar U, Hickey AM, Zhang F, Toida T, Dordick JS, Linhardt RJ. Ozonolysis of the double bond of the unsaturated uronate residue in low-molecular-weight heparin and K5 heparosan. Carbohydrate Research. 346: 1962-6. PMID 21742314 DOI: 10.1016/j.carres.2011.06.004  1
2011 Zhao W, Garron ML, Yang B, Xiao Z, Esko JD, Cygler M, Linhardt RJ. Asparagine 405 of heparin lyase II prevents the cleavage of glycosidic linkages proximate to a 3-O-sulfoglucosamine residue. Febs Letters. 585: 2461-6. PMID 21741976 DOI: 10.1016/j.febslet.2011.06.023  1
2011 Leach FE, Wolff JJ, Xiao Z, Ly M, Laremore TN, Arungundram S, Al-Mafraji K, Venot A, Boons GJ, Linhardt RJ, Amster IJ. Negative electron transfer dissociation Fourier transform mass spectrometry of glycosaminoglycan carbohydrates. European Journal of Mass Spectrometry (Chichester, England). 17: 167-76. PMID 21719917 DOI: 10.1255/ejms.1120  1
2011 Wang Z, Dordick JS, Linhardt RJ. Escherichia coli K5 heparosan fermentation and improvement by genetic engineering. Bioengineered Bugs. 2: 63-7. PMID 21636991 DOI: 10.4161/bbug.2.1.14201  1
2011 Otto NJ, Solakyildirim K, Linhardt RJ, DeAngelis PL. Comamonas testosteronan synthase, a bifunctional glycosyltransferase that produces a unique heparosan polysaccharide analog. Glycobiology. 21: 1331-40. PMID 21610195 DOI: 10.1093/glycob/cwr072  1
2011 Miyauchi M, Simmons TJ, Miao J, Gagner JE, Shriver ZH, Aich U, Dordick JS, Linhardt RJ. Electrospun polyvinylpyrrolidone fibers with high concentrations of ferromagnetic and superparamagnetic nanoparticles. Acs Applied Materials & Interfaces. 3: 1958-64. PMID 21561090 DOI: 10.1021/am200187x  1
2011 Vongchan P, Wutti-In Y, Sajomsang W, Gonil P, Kothan S, Linhardt RJ. N,N,N-Trimethyl chitosan nanoparticles for the delivery of monoclonal antibodies against hepatocellular carcinoma cells. Carbohydrate Polymers. 85: 215-220. PMID 21552341 DOI: 10.1016/j.carbpol.2011.02.018  1
2011 Yang B, Weyers A, Baik JY, Sterner E, Sharfstein S, Mousa SA, Zhang F, Dordick JS, Linhardt RJ. Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis. Analytical Biochemistry. 415: 59-66. PMID 21530482 DOI: 10.1016/j.ab.2011.04.003  1
2011 Wang Z, Yang B, Zhang Z, Ly M, Takieddin M, Mousa S, Liu J, Dordick JS, Linhardt RJ. Control of the heparosan N-deacetylation leads to an improved bioengineered heparin. Applied Microbiology and Biotechnology. 91: 91-9. PMID 21484210 DOI: 10.1007/s00253-011-3231-5  1
2011 Bera S, Linhardt RJ. Design and synthesis of unnatural heparosan and chondroitin building blocks Journal of Organic Chemistry. 76: 3181-3193. PMID 21438620 DOI: 10.1021/jo200076z  1
2011 Beaudet JM, Weyers A, Solakyildirim K, Yang B, Takieddin M, Mousa S, Zhang F, Linhardt RJ. Impact of autoclave sterilization on the activity and structure of formulated heparin. Journal of Pharmaceutical Sciences. 100: 3396-404. PMID 21416466 DOI: 10.1002/jps.22527  1
2011 Mora-Pale M, Meli L, Doherty TV, Linhardt RJ, Dordick JS. Room temperature ionic liquids as emerging solvents for the pretreatment of lignocellulosic biomass. Biotechnology and Bioengineering. 108: 1229-45. PMID 21337342 DOI: 10.1002/bit.23108  1
2011 Khurana A, Liu P, Mellone P, Lorenzon L, Vincenzi B, Datta K, Yang B, Linhardt RJ, Lingle W, Chien J, Baldi A, Shridhar V. HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells. Cancer Research. 71: 2152-61. PMID 21266348 DOI: 10.1158/0008-5472.CAN-10-3059  1
2011 Anand G, Zhang F, Linhardt RJ, Belfort G. Protein-associated water and secondary structure effect removal of blood proteins from metallic substrates Langmuir. 27: 1830-1836. PMID 21182242 DOI: 10.1021/la1041794  1
2011 Xiao Z, Tappen BR, Ly M, Zhao W, Canova LP, Guan H, Linhardt RJ. Heparin mapping using heparin lyases and the generation of a novel low molecular weight heparin. Journal of Medicinal Chemistry. 54: 603-10. PMID 21166465 DOI: 10.1021/jm101381k  1
2011 Wang Z, Flax LA, Kemp MM, Linhardt RJ, Baron MJ. Host and pathogen glycosaminoglycan-binding proteins modulate antimicrobial peptide responses in Drosophila melanogaster. Infection and Immunity. 79: 606-16. PMID 21078848 DOI: 10.1128/IAI.00254-10  1
2011 Li B, Liu H, Zhang Z, Stansfield HE, Dordick JS, Linhardt RJ. Analysis of glycosaminoglycans in stem cell glycomics. Methods in Molecular Biology (Clifton, N.J.). 690: 285-300. PMID 21043000 DOI: 10.1007/978-1-60761-962-8_19  1
2011 Yang B, Solakyildirim K, Chang Y, Linhardt RJ. Hyphenated techniques for the analysis of heparin and heparan sulfate. Analytical and Bioanalytical Chemistry. 399: 541-57. PMID 20853165 DOI: 10.1007/s00216-010-4117-6  1
2011 Liu Z, Xiao Z, Masuko S, Zhao W, Sterner E, Bansal V, Fareed J, Dordick J, Zhang F, Linhardt RJ. Mass balance analysis of contaminated heparin product. Analytical Biochemistry. 408: 147-56. PMID 20850409 DOI: 10.1016/j.ab.2010.09.015  1
2011 Xiao Z, Zhao W, Yang B, Zhang Z, Guan H, Linhardt RJ. Heparinase 1 selectivity for the 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages. Glycobiology. 21: 13-22. PMID 20729345 DOI: 10.1093/glycob/cwq123  1
2011 Ly M, Wang Z, Laremore TN, Zhang F, Zhong W, Pu D, Zagorevski DV, Dordick JS, Linhardt RJ. Analysis of E. coli K5 capsular polysaccharide heparosan. Analytical and Bioanalytical Chemistry. 399: 737-45. PMID 20407891 DOI: 10.1007/s00216-010-3679-7  1
2011 Park Y, Im AR, Joo EJ, Lee J, Park HG, Kang YH, Linhardt RJ, Kim YS. Conjugation of ginsenoside Rg3 with gold nanoparticles Bulletin of the Korean Chemical Society. 32: 286-290. DOI: 10.5012/bkcs.2011.32.1.286  1
2011 Fejes Z, Kurtán T, Raabe G, Fleischhauer J, Szilágyi L, Bényei A, Gál Z, Zhao W, Linhardt RJ, Cygler M, Herczegh P. Synthesis, structural, and biological studies on a pseudodisaccharide containing a bicyclic, bridged carba-sugar Tetrahedron Asymmetry. 22: 1404-1410. DOI: 10.1016/j.tetasy.2011.07.023  1
2011 Leach FE, Xiao Z, Laremore TN, Linhardt RJ, Amster IJ. Electron detachment dissociation and infrared multiphoton dissociation of heparin tetrasaccharides International Journal of Mass Spectrometry. 308: 253-259. DOI: 10.1016/j.ijms.2011.08.029  1
2011 Laremore TN, Leach FE, Amster IJ, Linhardt RJ. Electrospray ionization Fourier transform mass spectrometric analysis of intact bikunin glycosaminoglycan from normal human plasma International Journal of Mass Spectrometry. 305: 109-115. DOI: 10.1016/j.ijms.2010.09.020  1
2011 Vongchan P, Wutti-In Y, Sajomsang W, Gonil P, Kothan S, Linhardt RJ. N,N,N-Trimethyl chitosan nanoparticles for the delivery of monoclonal antibodies against hepatocellular carcinoma cells Carbohydrate Polymers. 85: 215-220. DOI: 10.1016/j.carbpol.2011.02.018  1
2011 Simmons TJ, Lee SH, Miao J, Miyauchi M, Park TJ, Bale SS, Pangule R, Bult J, Martin JG, Dordick JS, Linhardt RJ. Preparation of synthetic wood composites using ionic liquids Wood Science and Technology. 45: 719-733. DOI: 10.1007/s00226-010-0395-6  1
2010 Beccati D, Roy S, Yu F, Gunay NS, Capila I, Lech M, Linhardt RJ, Venkataraman G. Identification of a novel structure in heparin generated by potassium permanganate oxidation. Carbohydrate Polymers. 82: 699-705. PMID 25147414 DOI: 10.1016/j.carbpol.2010.05.038  1
2010 Miao J, Miyauchi M, Simmons TJ, Dordick JS, Linhardt RJ. Electrospinning of nanomaterials and applications in electronic components and devices. Journal of Nanoscience and Nanotechnology. 10: 5507-19. PMID 21133069 DOI: 10.1166/jnn.2010.3073  1
2010 Liu Z, Masuko S, Solakyildirim K, Pu D, Linhardt RJ, Zhang F. Glycosaminoglycans of the porcine central nervous system. Biochemistry. 49: 9839-47. PMID 20954748 DOI: 10.1021/bi101305b  1
2010 Laremore TN, Leach FE, Solakyildirim K, Amster IJ, Linhardt RJ. Glycosaminoglycan characterization by electrospray ionization mass spectrometry including Fourier transform mass spectrometry Methods in Enzymology. 478: 79-108. PMID 20816475 DOI: 10.1016/S0076-6879(10)78003-4  1
2010 Liu R, Xu Y, Chen M, Weïwer M, Zhou X, Bridges AS, DeAngelis PL, Zhang Q, Linhardt RJ, Liu J. Chemoenzymatic design of heparan sulfate oligosaccharides. The Journal of Biological Chemistry. 285: 34240-9. PMID 20729556 DOI: 10.1074/jbc.M110.159152  1
2010 Wang Z, Ly M, Zhang F, Zhong W, Suen A, Hickey AM, Dordick JS, Linhardt RJ. E. coli K5 fermentation and the preparation of heparosan, a bioengineered heparin precursor. Biotechnology and Bioengineering. 107: 964-73. PMID 20717972 DOI: 10.1002/bit.22898  1
2010 Laremore TN, Ly M, Zhang Z, Solakyildirim K, McCallum SA, Owens RT, Linhardt RJ. Domain structure elucidation of human decorin glycosaminoglycans. The Biochemical Journal. 431: 199-205. PMID 20707770 DOI: 10.1042/BJ20100788  1
2010 Cai C, Liu J, Du Y, Linhardt RJ. Stereoselective total synthesis of (-)-cleistenolide. The Journal of Organic Chemistry. 75: 5754-6. PMID 20704451 DOI: 10.1021/jo101059e  1
2010 Miyauchi M, Miao J, Simmons TJ, Lee JW, Doherty TV, Dordick JS, Linhardt RJ. Conductive cable fibers with insulating surface prepared by coaxial electrospinning of multiwalled nanotubes and cellulose. Biomacromolecules. 11: 2440-5. PMID 20690644 DOI: 10.1021/bm1006129  1
2010 Joo EJ, Yang H, Park Y, Park NY, Toida T, Linhardt RJ, Kim YS. Induction of nucleolin translocation by acharan sulfate in A549 human lung adenocarcinoma. Journal of Cellular Biochemistry. 110: 1272-8. PMID 20564223 DOI: 10.1002/jcb.22643  1
2010 Martin JG, Beaudet JM, Dordick JS, Linhardt RJ. Artificial organelles: digital microfluidic platform for proteoglycan and glycoprotein biosynthesis. Thescientificworldjournal. 10: 997-1000. PMID 20526531 DOI: 10.1100/tsw.2010.95  1
2010 Burana-osot J, Soonthornchareonnon N, Hosoyama S, Linhardt RJ, Toida T. Partial depolymerization of pectin by a photochemical reaction. Carbohydrate Research. 345: 1205-10. PMID 20451177 DOI: 10.1016/j.carres.2010.04.007  1
2010 Ly M, Laremore TN, Linhardt RJ. Proteoglycomics: recent progress and future challenges. Omics : a Journal of Integrative Biology. 14: 389-99. PMID 20450439 DOI: 10.1089/omi.2009.0123  1
2010 Volpi N, Linhardt RJ. High-performance liquid chromatography-mass spectrometry for mapping and sequencing glycosaminoglycan-derived oligosaccharides. Nature Protocols. 5: 993-1004. PMID 20448545 DOI: 10.1038/nprot.2010.48  1
2010 Shaya D, Zhao W, Garron ML, Xiao Z, Cui Q, Zhang Z, Sulea T, Linhardt RJ, Cygler M. Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate. The Journal of Biological Chemistry. 285: 20051-61. PMID 20404324 DOI: 10.1074/jbc.M110.101071  1
2010 Garg HG, Mrabat H, Yu L, Freeman C, Li B, Zhang F, Linhardt RJ, Hales CA. Effect of carboxyl-reduced heparin on the growth inhibition of bovine pulmonary artery smooth muscle cells. Carbohydrate Research. 345: 1084-7. PMID 20399420 DOI: 10.1016/j.carres.2010.03.026  1
2010 Wolff JJ, Leach FE, Laremore TN, Kaplan DA, Easterling ML, Linhardt RJ, Amster IJ. Negative electron transfer dissociation of glycosaminoglycans Analytical Chemistry. 82: 3460-3466. PMID 20380445 DOI: 10.1021/ac100554a  1
2010 Laremore TN, Ly M, Solakyildirim K, Zagorevski DV, Linhardt RJ. High-resolution preparative separation of glycosaminoglycan oligosaccharides by polyacrylamide gel electrophoresis. Analytical Biochemistry. 401: 236-41. PMID 20211145 DOI: 10.1016/j.ab.2010.03.004  1
2010 Yu L, Garg HG, Li B, Linhardt RJ, Hales CA. Antitumor effect of butanoylated heparin with low anticoagulant activity on lung cancer growth in mice and rats. Current Cancer Drug Targets. 10: 229-41. PMID 20201787 DOI: 10.2174/156800910791054176  1
2010 Kwon SJ, Kim MI, Ku B, Coulombel L, Kim JH, Shawky JH, Linhardt RJ, Dordick JS. Unnatural polyketide analogues selectively target the HER signaling pathway in human breast cancer cells. Chembiochem : a European Journal of Chemical Biology. 11: 573-80. PMID 20058253 DOI: 10.1002/cbic.200900674  1
2010 Kemp MM, Linhardt RJ. Heparin-based nanoparticles. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 2: 77-87. PMID 20049832 DOI: 10.1002/wnan.68  1
2010 Wang Z, Zhang Z, McCallum SA, Linhardt RJ. Nuclear magnetic resonance quantification for monitoring heparosan K5 capsular polysaccharide production. Analytical Biochemistry. 398: 275-7. PMID 20018166 DOI: 10.1016/j.ab.2009.12.005  1
2010 Im AR, Park Y, Sim JS, Zhang Z, Liu Z, Linhardt RJ, Kim YS. Glycosaminoglycans from earthworms (Eisenia andrei). Glycoconjugate Journal. 27: 249-57. PMID 20013352 DOI: 10.1007/s10719-009-9273-6  1
2010 Bhattacharyya S, Liu H, Zhang Z, Jam M, Dudeja PK, Michel G, Linhardt RJ, Tobacman JK. Carrageenan-induced innate immune response is modified by enzymes that hydrolyze distinct galactosidic bonds. The Journal of Nutritional Biochemistry. 21: 906-13. PMID 19864123 DOI: 10.1016/j.jnutbio.2009.07.002  1
2010 Solakyildirim K, Zhang Z, Linhardt RJ. Ultraperformance liquid chromatography with electrospray ionization ion trap mass spectrometry for chondroitin disaccharide analysis. Analytical Biochemistry. 397: 24-8. PMID 19769936 DOI: 10.1016/j.ab.2009.09.031  1
2010 Bhattacharyya S, Solakyildirim K, Zhang Z, Chen ML, Linhardt RJ, Tobacman JK. Cell-bound IL-8 increases in bronchial epithelial cells after arylsulfatase B silencing due to sequestration with chondroitin-4-sulfate. American Journal of Respiratory Cell and Molecular Biology. 42: 51-61. PMID 19346317 DOI: 10.1165/rcmb.2008-0482OC  1
2009 Weïwer M, Chen CC, Kemp MM, Linhardt RJ. Synthesis and Biological Evaluation of Non-Hydrolizable 1,2,3-Triazole Linked Sialic Acid Derivatives as Neuraminidase Inhibitors. European Journal of Organic Chemistry. 2009. PMID 24223493 DOI: 10.1002/ejoc.200900117  1
2009 Zhang Z, Linhardt RJ. Sequence Analysis of Native Oligosaccharides Using Negative ESI Tandem MS. Current Analytical Chemistry. 5: 225-237. PMID 23459600 DOI: 10.2174/157341109788680291  1
2009 Eker B, Zagorevski D, Zhu G, Linhardt RJ, Dordick JS. ENZYMATIC POLYMERIZATION OF PHENOLS IN ROOM TEMPERATURE IONIC LIQUIDS. Journal of Molecular Catalysis. B, Enzymatic. 59: 177-184. PMID 20161409 DOI: 10.1016/j.molcatb.2009.02.018  1
2009 Bhattacharyya S, Solakyildirim K, Zhang Z, Linhardt RJ, Tobacman JK. Chloroquine reduces arylsulphatase B activity and increases chondroitin-4-sulphate: implications for mechanisms of action and resistance. Malaria Journal. 8: 303. PMID 20017940 DOI: 10.1186/1475-2875-8-303  1
2009 Kemp MM, Kumar A, Mousa S, Dyskin E, Yalcin M, Ajayan P, Linhardt RJ, Mousa SA. Gold and silver nanoparticles conjugated with heparin derivative possess anti-angiogenesis properties. Nanotechnology. 20: 455104. PMID 19822927 DOI: 10.1088/0957-4484/20/45/455104  1
2009 Guerrini M, Zhang Z, Shriver Z, Naggi A, Masuko S, Langer R, Casu B, Linhardt RJ, Torri G, Sasisekharan R. Orthogonal analytical approaches to detect potential contaminants in heparin. Proceedings of the National Academy of Sciences of the United States of America. 106: 16956-61. PMID 19805108 DOI: 10.1073/pnas.0906861106  1
2009 Han YH, Garron ML, Kim HY, Kim WS, Zhang Z, Ryu KS, Shaya D, Xiao Z, Cheong C, Kim YS, Linhardt RJ, Jeon YH, Cygler M. Structural snapshots of heparin depolymerization by heparin lyase I. The Journal of Biological Chemistry. 284: 34019-27. PMID 19801541 DOI: 10.1074/jbc.M109.025338  1
2009 Laremore TN, Zhang F, Dordick JS, Liu J, Linhardt RJ. Recent progress and applications in glycosaminoglycan and heparin research. Current Opinion in Chemical Biology. 13: 633-40. PMID 19781979 DOI: 10.1016/j.cbpa.2009.08.017  1
2009 Han J, Zhang F, Xie J, Linhardt RJ, Hiebert LM. Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin. Cardiovascular Diabetology. 8: 46. PMID 19695080 DOI: 10.1186/1475-2840-8-46  1
2009 Ra HJ, Harju-Baker S, Zhang F, Linhardt RJ, Wilson CL, Parks WC. Control of promatrilysin (MMP7) activation and substrate-specific activity by sulfated glycosaminoglycans. The Journal of Biological Chemistry. 284: 27924-32. PMID 19654318 DOI: 10.1074/jbc.M109.035147  1
2009 Zhang Z, Li B, Suwan J, Zhang F, Wang Z, Liu H, Mulloy B, Linhardt RJ. Analysis of pharmaceutical heparins and potential contaminants using (1)H-NMR and PAGE. Journal of Pharmaceutical Sciences. 98: 4017-26. PMID 19642166 DOI: 10.1002/jps.21729  1
2009 Burana-osot J, Hosoyama S, Nagamoto Y, Suzuki S, Linhardt RJ, Toida T. Photolytic depolymerization of alginate. Carbohydrate Research. 344: 2023-7. PMID 19616772 DOI: 10.1016/j.carres.2009.06.027  1
2009 Martin JG, Gupta M, Xu Y, Akella S, Liu J, Dordick JS, Linhardt RJ. Toward an artificial Golgi: redesigning the biological activities of heparan sulfate on a digital microfluidic chip. Journal of the American Chemical Society. 131: 11041-8. PMID 19591465 DOI: 10.1021/ja903038d  1
2009 Zhang F, Zhang Z, Lin X, Beenken A, Eliseenkova AV, Mohammadi M, Linhardt RJ. Compositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexes. Biochemistry. 48: 8379-86. PMID 19591432 DOI: 10.1021/bi9006379  1
2009 Mora-Pale M, Weïwer M, Yu J, Linhardt RJ, Dordick JS. Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols. Bioorganic & Medicinal Chemistry. 17: 5146-52. PMID 19523836 DOI: 10.1016/j.bmc.2009.05.061  1
2009 Kemp MM, Kumar A, Clement D, Ajayan P, Mousa S, Linhardt RJ. Hyaluronan- and heparin-reduced silver nanoparticles with antimicrobial properties. Nanomedicine (London, England). 4: 421-9. PMID 19505245 DOI: 10.2217/nnm.09.24  1
2009 Suwan J, Zhang Z, Li B, Vongchan P, Meepowpan P, Zhang F, Mousa SA, Mousa S, Premanode B, Kongtawelert P, Linhardt RJ. Sulfonation of papain-treated chitosan and its mechanism for anticoagulant activity. Carbohydrate Research. 344: 1190-6. PMID 19476923 DOI: 10.1016/j.carres.2009.04.016  1
2009 Wolff JJ, Laremore TN, Leach FE, Linhardt RJ, Amster IJ. Electron capture dissociation, electron detachment dissociation and infrared multiphoton dissociation of sucrose octasulfate European Journal of Mass Spectrometry. 15: 275-281. PMID 19423912 DOI: 10.1255/ejms.951  1
2009 Zhang Z, Xie J, Liu H, Liu J, Linhardt RJ. Quantification of heparan sulfate disaccharides using ion-pairing reversed-phase microflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry. Analytical Chemistry. 81: 4349-55. PMID 19402671 DOI: 10.1021/ac9001707  1
2009 Sava IG, Zhang F, Toma I, Theilacker C, Li B, Baumert TF, Holst O, Linhardt RJ, Huebner J. Novel interactions of glycosaminoglycans and bacterial glycolipids mediate binding of enterococci to human cells. The Journal of Biological Chemistry. 284: 18194-201. PMID 19395379 DOI: 10.1074/jbc.M901460200  1
2009 Li B, Suwan J, Martin JG, Zhang F, Zhang Z, Hoppensteadt D, Clark M, Fareed J, Linhardt RJ. Oversulfated chondroitin sulfate interaction with heparin-binding proteins: new insights into adverse reactions from contaminated heparins. Biochemical Pharmacology. 78: 292-300. PMID 19389385 DOI: 10.1016/j.bcp.2009.04.012  1
2009 Simmons TJ, Bult J, Hashim DP, Linhardt RJ, Ajayan PM. Noncovalent functionalization as an alternative to oxidative acid treatment of single wall carbon nanotubes with applications for polymer composites. Acs Nano. 3: 865-70. PMID 19334688 DOI: 10.1021/nn800860m  1
2009 Toida T, Sato K, Sakamoto N, Sakai S, Hosoyama S, Linhardt RJ. Solvolytic depolymerization of chondroitin and dermatan sulfates. Carbohydrate Research. 344: 888-93. PMID 19272590 DOI: 10.1016/j.carres.2009.02.010  1
2009 Liu H, Zhang Z, Linhardt RJ. Lessons learned from the contamination of heparin. Natural Product Reports. 26: 313-21. PMID 19240943 DOI: 10.1039/b819896a  1
2009 Volpi N, Maccari F, Linhardt RJ. Quantitative capillary electrophoresis determination of oversulfated chondroitin sulfate as a contaminant in heparin preparations. Analytical Biochemistry. 388: 140-5. PMID 19232311 DOI: 10.1016/j.ab.2009.02.012  1
2009 Kemp MM, Kumar A, Mousa S, Park TJ, Ajayan P, Kubotera N, Mousa SA, Linhardt RJ. Synthesis of gold and silver nanoparticles stabilized with glycosaminoglycans having distinctive biological activities. Biomacromolecules. 10: 589-95. PMID 19226107 DOI: 10.1021/bm801266t  1
2009 Lee SH, Doherty TV, Linhardt RJ, Dordick JS. Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis. Biotechnology and Bioengineering. 102: 1368-76. PMID 19090482 DOI: 10.1002/bit.22179  1
2009 Zhang Z, Park Y, Kemp MM, Zhao W, Im AR, Shaya D, Cygler M, Kim YS, Linhardt RJ. Liquid chromatography-mass spectrometry to study chondroitin lyase action pattern. Analytical Biochemistry. 385: 57-64. PMID 18992215 DOI: 10.1016/j.ab.2008.10.014  1
2009 Zhang F, Zhang Z, Thistle R, McKeen L, Hosoyama S, Toida T, Linhardt RJ, Page-McCaw P. Structural characterization of glycosaminoglycans from zebrafish in different ages. Glycoconjugate Journal. 26: 211-8. PMID 18777207 DOI: 10.1007/s10719-008-9177-x  1
2008 Leach FE, Wolff JJ, Laremore TN, Linhardt RJ, Amster IJ. EVALUATION OF THE EXPERIMENTAL PARAMETERS WHICH CONTROL ELECTRON DETACHMENT DISSOCIATION, AND THEIR EFFECT ON THE FRAGMENTATION EFFICIENCY OF GLYCOSAMINOGLYCAN CARBOHYDRATES. International Journal of Mass Spectrometry. 276: 110-115. PMID 19802340 DOI: 10.1016/j.ijms.2008.05.017  1
2008 Kim JH, Huang F, Ly M, Linhardt RJ. Stereoselective synthesis of a C-linked neuraminic acid disaccharide: potential building block for the synthesis of C-analogues of polysialic acids. The Journal of Organic Chemistry. 73: 9497-500. PMID 19006371 DOI: 10.1021/jo801946y  1
2008 Park TJ, Lee SH, Simmons TJ, Martin JG, Mousa SA, Snezhkova EA, Sarnatskaya VV, Nikolaev VG, Linhardt RJ. Heparin-cellulose-charcoal composites for drug detoxification prepared using room temperature ionic liquids. Chemical Communications (Cambridge, England). 5022-4. PMID 18931773 DOI: 10.1039/b809791g  1
2008 Volpi N, Zhang Z, Linhardt RJ. Mass spectrometry for the characterization of unsulfated chondroitin oligosaccharides from 2-mers to 16-mers. Comparison with hyaluronic acid oligomers. Rapid Communications in Mass Spectrometry : Rcm. 22: 3526-30. PMID 18853395 DOI: 10.1002/rcm.3760  1
2008 Zhang Z, McCallum SA, Xie J, Nieto L, Corzana F, Jiménez-Barbero J, Chen M, Liu J, Linhardt RJ. Solution structures of chemoenzymatically synthesized heparin and its precursors. Journal of the American Chemical Society. 130: 12998-3007. PMID 18767845 DOI: 10.1021/ja8026345  1
2008 Weïwer M, Sherwood T, Green DE, Chen M, DeAngelis PL, Liu J, Linhardt RJ. Synthesis of uridine 5'-diphosphoiduronic acid: a potential substrate for the chemoenzymatic synthesis of heparin. The Journal of Organic Chemistry. 73: 7631-7. PMID 18759479 DOI: 10.1021/jo801409c  1
2008 Zhang Z, Weïwer M, Li B, Kemp MM, Daman TH, Linhardt RJ. Oversulfated chondroitin sulfate: impact of a heparin impurity, associated with adverse clinical events, on low-molecular-weight heparin preparation. Journal of Medicinal Chemistry. 51: 5498-501. PMID 18754653 DOI: 10.1021/jm800785t  1
2008 Park TJ, Lee MY, Dordick JS, Linhardt RJ. Signal amplification of target protein on heparin glycan microarray. Analytical Biochemistry. 383: 116-21. PMID 18722996 DOI: 10.1016/j.ab.2008.07.037  1
2008 Park Y, Zhang Z, Linhardt RJ, LeMosy EK. Distinct heparan sulfate compositions in wild-type and pipe-mutant eggshell matrix. Fly. 2: 175-9. PMID 18719407  1
2008 Vongchan P, Nawarawong W, Linhardt RJ. Modification of solid phase red cell adherence assay for the detection of platelet antibodies in patients with thrombocytopenia. American Journal of Clinical Pathology. 130: 455-66. PMID 18701420 DOI: 10.1309/1QWTQFMF0Q9JEAGR  1
2008 Yu J, Weïwer M, Linhardt RJ, Dordick JS. The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases. Current Vascular Pharmacology. 6: 204-17. PMID 18673160 DOI: 10.2174/157016108784911984  1
2008 Park Y, Zhang Z, Laremore TN, Li B, Sim JS, Im AR, Ahn MY, Kim YS, Linhardt RJ. Variation of acharan sulfate and monosaccharide composition and analysis of neutral N-glycans in African giant snail (Achatina fulica). Glycoconjugate Journal. 25: 863-77. PMID 18670878 DOI: 10.1007/s10719-008-9149-1  1
2008 de Agostini AI, Dong JC, de Vantéry Arrighi C, Ramus MA, Dentand-Quadri I, Thalmann S, Ventura P, Ibecheole V, Monge F, Fischer AM, HajMohammadi S, Shworak NW, Zhang L, Zhang Z, Linhardt RJ. Human follicular fluid heparan sulfate contains abundant 3-O-sulfated chains with anticoagulant activity. The Journal of Biological Chemistry. 283: 28115-24. PMID 18669628 DOI: 10.1074/jbc.M805338200  1
2008 Wolff JJ, Laremore TN, Aslam H, Linhardt RJ, Amster IJ. Electron-Induced Dissociation of Glycosaminoglycan Tetrasaccharides Journal of the American Society For Mass Spectrometry. 19: 1449-1458. PMID 18657442 DOI: 10.1016/j.jasms.2008.06.024  1
2008 Garg HG, Mrabat H, Yu L, Freeman C, Li B, Zhang F, Linhardt RJ, Hales CA. Significance of the 2-O-sulfo group of L-iduronic acid residues in heparin on the growth inhibition of bovine pulmonary artery smooth muscle cells. Carbohydrate Research. 343: 2406-10. PMID 18656855 DOI: 10.1016/j.carres.2008.06.022  1
2008 Volpi N, Maccari F, Linhardt RJ. Capillary electrophoresis of complex natural polysaccharides. Electrophoresis. 29: 3095-106. PMID 18633943 DOI: 10.1002/elps.200800109  1
2008 Varki AP, Baum LG, Bellis SL, Cummings RD, Esko JD, Hart GW, Linhardt RJ, Lowe JB, McEver RP, Srivastava A, Sarkar R. Working group report: the roles of glycans in hemostasis, inflammation and vascular biology. Glycobiology. 18: 747-9. PMID 18621991 DOI: 10.1093/glycob/cwn065  1
2008 Nam JH, Zhang F, Ermonval M, Linhardt RJ, Sharfstein ST. The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells Biotechnology and Bioengineering. 100: 1178-1192. PMID 18553404 DOI: 10.1002/bit.21853  1
2008 Wolff JJ, Laremore TN, Busch AM, Linhardt RJ, Amster IJ. Influence of Charge State and Sodium Cationization on the Electron Detachment Dissociation and Infrared Multiphoton Dissociation of Glycosaminoglycan Oligosaccharides Journal of the American Society For Mass Spectrometry. 19: 790-798. PMID 18499037 DOI: 10.1016/j.jasms.2008.03.010  1
2008 Copeland R, Balasubramaniam A, Tiwari V, Zhang F, Bridges A, Linhardt RJ, Shukla D, Liu J. Using a 3-O-sulfated heparin octasaccharide to inhibit the entry of herpes simplex virus type 1. Biochemistry. 47: 5774-83. PMID 18457417 DOI: 10.1021/bi800205t  1
2008 Guerrini M, Beccati D, Shriver Z, Naggi A, Viswanathan K, Bisio A, Capila I, Lansing JC, Guglieri S, Fraser B, Al-Hakim A, Gunay NS, Zhang Z, Robinson L, Buhse L, ... ... Linhardt RJ, et al. Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nature Biotechnology. 26: 669-75. PMID 18437154 DOI: 10.1038/nbt1407  1
2008 Murugesan S, Xie J, Linhardt RJ. Immobilization of heparin: approaches and applications. Current Topics in Medicinal Chemistry. 8: 80-100. PMID 18289079 DOI: 10.2174/156802608783378891  1
2008 Bhattacharyya S, Gill R, Chen ML, Zhang F, Linhardt RJ, Dudeja PK, Tobacman JK. Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells. The Journal of Biological Chemistry. 283: 10550-8. PMID 18252714 DOI: 10.1074/jbc.M708833200  1
2008 Chi L, Wolff JJ, Laremore TN, Restaino OF, Xie J, Schiraldi C, Toida T, Amster IJ, Linhardt RJ. Structural analysis of bikunin glycosaminoglycan Journal of the American Chemical Society. 130: 2617-2625. PMID 18247611 DOI: 10.1021/ja0778500  1
2008 Warda M, Zhang F, Radwan M, Zhang Z, Kim N, Kim YN, Linhardt RJ, Han J. Is human placenta proteoglycan remodeling involved in pre-eclampsia? Glycoconjugate Journal. 25: 441-50. PMID 18161024 DOI: 10.1007/s10719-007-9090-8  1
2008 Silipo A, Zhang Z, Cañada FJ, Molinaro A, Linhardt RJ, Jiménez-Barbero J. Conformational analysis of a dermatan sulfate-derived tetrasaccharide by NMR, molecular modeling, and residual dipolar couplings. Chembiochem : a European Journal of Chemical Biology. 9: 240-52. PMID 18072186 DOI: 10.1002/cbic.200700400  1
2008 Zhang Z, Xie J, Liu J, Linhardt RJ. Tandem MS can distinguish hyaluronic acid from N-acetylheparosan. Journal of the American Society For Mass Spectrometry. 19: 82-90. PMID 18061476 DOI: 10.1016/j.jasms.2007.10.012  1
2008 Wolff JJ, Laremore TN, Busch AM, Linhardt RJ, Amster IJ. Electron Detachment Dissociation of Dermatan Sulfate Oligosaccharides Journal of the American Society For Mass Spectrometry. 19: 294-304. PMID 18055211 DOI: 10.1016/j.jasms.2007.10.007  1
2007 Mousa SA, Zhang F, Aljada A, Chaturvedi S, Takieddin M, Zhang H, Chi L, Castelli MC, Friedman K, Goldberg MM, Linhardt RJ. Pharmacokinetics and pharmacodynamics of oral heparin solid dosage form in healthy human subjects. Journal of Clinical Pharmacology. 47: 1508-20. PMID 18048572 DOI: 10.1177/0091270007307242  1
2007 Eker B, Asuri P, Murugesan S, Linhardt RJ, Dordick JS. Enzyme-carbon nanotube conjugates in room-temperature ionic liquids. Applied Biochemistry and Biotechnology. 143: 153-63. PMID 18025604 DOI: 10.1007/s12010-007-0035-2  1
2007 Nairn AV, Kinoshita-Toyoda A, Toyoda H, Xie J, Harris K, Dalton S, Kulik M, Pierce JM, Toida T, Moremen KW, Linhardt RJ. Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation. Journal of Proteome Research. 6: 4374-87. PMID 17915907 DOI: 10.1021/pr070446f  1
2007 Linhardt RJ, Kim JH. Combinatorial enzymatic synthesis of heparan sulfate. Chemistry & Biology. 14: 972-3. PMID 17884627 DOI: 10.1016/j.chembiol.2007.09.002  1
2007 Pushparaj VL, Shaijumon MM, Kumar A, Murugesan S, Ci L, Vajtai R, Linhardt RJ, Nalamasu O, Ajayan PM. Flexible energy storage devices based on nanocomposite paper. Proceedings of the National Academy of Sciences of the United States of America. 104: 13574-7. PMID 17699622 DOI: 10.1073/pnas.0706508104  1
2007 Vorup-Jensen T, Chi L, Gjelstrup LC, Jensen UB, Jewett CA, Xie C, Shimaoka M, Linhardt RJ, Springer TA. Binding between the integrin alphaXbeta2 (CD11c/CD18) and heparin. The Journal of Biological Chemistry. 282: 30869-77. PMID 17699512 DOI: 10.1074/jbc.M706114200  1
2007 Zhang Z, Xie J, Zhang F, Linhardt RJ. Thin-layer chromatography for the analysis of glycosaminoglycan oligosaccharides. Analytical Biochemistry. 371: 118-20. PMID 17679101 DOI: 10.1016/j.ab.2007.07.003  1
2007 Linhardt RJ, Dordick JS, Deangelis PL, Liu J. Enzymatic synthesis of glycosaminoglycan heparin. Seminars in Thrombosis and Hemostasis. 33: 453-65. PMID 17629842 DOI: 10.1055/s-2007-982076  1
2007 Sinnis P, Coppi A, Toida T, Toyoda H, Kinoshita-Toyoda A, Xie J, Kemp MM, Linhardt RJ. Mosquito heparan sulfate and its potential role in malaria infection and transmission. The Journal of Biological Chemistry. 282: 25376-84. PMID 17597060 DOI: 10.1074/jbc.M704698200  1
2007 Sakai S, Hirano K, Toyoda H, Linhardt RJ, Toida T. Matrix assisted laser desorption ionization-time of flight mass spectrometry analysis of hyaluronan oligosaccharides. Analytica Chimica Acta. 593: 207-13. PMID 17543609 DOI: 10.1016/j.aca.2007.05.005  1
2007 Ma Q, Cornelli U, Hanin I, Jeske WP, Linhardt RJ, Walenga JM, Fareed J, Lee JM. Heparin oligosaccharides as potential therapeutic agents in senile dementia. Current Pharmaceutical Design. 13: 1607-16. PMID 17504153  1
2007 Du Y, Liu J, Linhardt RJ. Facile synthesis of (+/-)-paeonilide. The Journal of Organic Chemistry. 72: 3952-4. PMID 17411097 DOI: 10.1021/jo0701278  1
2007 Yuan X, Ress DK, Linhardt RJ. Synthesis of nor-C-linked neuraminic acid disaccharide: a versatile precursor of C-analogs of oligosialic acids and gangliosides. The Journal of Organic Chemistry. 72: 3085-8. PMID 17371069 DOI: 10.1021/jo0623787  1
2007 Zhang F, McLellan JS, Ayala AM, Leahy DJ, Linhardt RJ. Kinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway. Biochemistry. 46: 3933-41. PMID 17348690 DOI: 10.1021/bi6025424  1
2007 Laremore TN, Linhardt RJ. Improved matrix-assisted laser desorption/ionization mass spectrometric detection of glycosaminoglycan disaccharides as cesium salts. Rapid Communications in Mass Spectrometry : Rcm. 21: 1315-20. PMID 17340574 DOI: 10.1002/rcm.2964  1
2007 Goetz R, Beenken A, Ibrahimi OA, Kalinina J, Olsen SK, Eliseenkova AV, Xu C, Neubert TA, Zhang F, Linhardt RJ, Yu X, White KE, Inagaki T, Kliewer SA, Yamamoto M, et al. Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Molecular and Cellular Biology. 27: 3417-28. PMID 17339340 DOI: 10.1128/MCB.02249-06  1
2007 Murugesan S, Mousa SA, O'connor LJ, Lincoln DW, Linhardt RJ. Carbon inhibits vascular endothelial growth factor- and fibroblast growth factor-promoted angiogenesis. Febs Letters. 581: 1157-60. PMID 17331505 DOI: 10.1016/j.febslet.2007.02.022  1
2007 Hrtska SC, Kemp MM, Muñoz EM, Azizad O, Banerjee M, Raposo C, Kumaran J, Ghosh P, Linhardt RJ. Investigation of the mechanism of binding between internalin B and heparin using surface plasmon resonance. Biochemistry. 46: 2697-706. PMID 17305366 DOI: 10.1021/bi062021x  1
2007 Laremore TN, Zhang F, Linhardt RJ. Ionic liquid matrix for direct UV-MALDI-TOF-MS analysis of dermatan sulfate and chondroitin sulfate oligosaccharides. Analytical Chemistry. 79: 1604-10. PMID 17297962 DOI: 10.1021/ac061688m  1
2007 Kumar A, Murugesan S, Pushparaj V, Xie J, Soldano C, John G, Nalamasu O, Ajayan PM, Linhardt RJ. Conducting organic-metallic composite submicrometer rods based on ionic liquids. Small (Weinheim An Der Bergstrasse, Germany). 3: 429-33. PMID 17262867 DOI: 10.1002/smll.200600442  1
2007 Wolff JJ, Chi L, Linhardt RJ, Amster IJ. Distinguishing glucuronic from iduronic acid in glycosaminoglycan tetrasaccharides by using electron detachment dissociation Analytical Chemistry. 79: 2015-2022. PMID 17253657 DOI: 10.1021/ac061636x  1
2007 Park TJ, Weïwer M, Yuan X, Baytas SN, Munoz EM, Murugesan S, Linhardt RJ. Glycosylation in room temperature ionic liquid using unprotected and unactivated donors. Carbohydrate Research. 342: 614-20. PMID 17173880 DOI: 10.1016/j.carres.2006.11.022  1
2007 Krupa JC, Shaya D, Chi L, Linhardt RJ, Cygler M, Withers SG, Mort JS. Quantitative continuous assay for hyaluronan synthase. Analytical Biochemistry. 361: 218-25. PMID 17173853 DOI: 10.1016/j.ab.2006.11.011  1
2007 Tracy BS, Avci FY, Linhardt RJ, DeAngelis PL. Acceptor specificity of the Pasteurella hyaluronan and chondroitin synthases and production of chimeric glycosaminoglycans. The Journal of Biological Chemistry. 282: 337-44. PMID 17099217 DOI: 10.1074/jbc.M607569200  1
2007 Wolff JJ, Amster IJ, Chi L, Linhardt RJ. Electron Detachment Dissociation of Glycosaminoglycan Tetrasaccharides Journal of the American Society For Mass Spectrometry. 18: 234-244. PMID 17074503 DOI: 10.1016/j.jasms.2006.09.020  1
2007 Vongchan P, Linhardt RJ. Expression of human liver HSPGs on acute myeloid leukemia. Clinical Immunology (Orlando, Fla.). 122: 194-206. PMID 17035092 DOI: 10.1016/j.clim.2006.08.017  1
2006 Toida T, Sakai S, Akiyama H, Linhardt RJ. Immunological activity of chondroitin sulfate. Advances in Pharmacology (San Diego, Calif.). 53: 403-15. PMID 17239777 DOI: 10.1016/S1054-3589(05)53019-9  1
2006 Linhardt RJ, Avci FY, Toida T, Kim YS, Cygler M. CS lyases: structure, activity, and applications in analysis and the treatment of diseases. Advances in Pharmacology (San Diego, Calif.). 53: 187-215. PMID 17239767 DOI: 10.1016/S1054-3589(05)53009-6  1
2006 Du Y, Chen Q, Linhardt RJ. The first total synthesis of sporiolide A. The Journal of Organic Chemistry. 71: 8446-51. PMID 17064018 DOI: 10.1021/jo0615504  1
2006 Kumar A, Pushparaj VL, Murugesan S, Viswanathan G, Nalamasu R, Linhardt RJ, Nalamasu O, Ajayan PM. Synthesis of silica-gold nanocomposites and their porous nanoparticles by an in-situ approach. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 8631-4. PMID 17014096 DOI: 10.1021/la060869g  1
2006 Ha YW, Na YC, Seo JJ, Kim SN, Linhardt RJ, Kim YS. Qualitative and quantitative determination of ten major saponins in Platycodi Radix by high performance liquid chromatography with evaporative light scattering detection and mass spectrometry. Journal of Chromatography. A. 1135: 27-35. PMID 17007864 DOI: 10.1016/j.chroma.2006.09.015  1
2006 Warda M, Toida T, Zhang F, Sun P, Munoz E, Xie J, Linhardt RJ. Isolation and characterization of heparan sulfate from various murine tissues. Glycoconjugate Journal. 23: 555-63. PMID 17006646 DOI: 10.1007/s10719-006-7668-1  1
2006 Mousa SA, Feng X, Xie J, Du Y, Hua Y, He H, O'Connor L, Linhardt RJ. Synthetic oligosaccharide stimulates and stabilizes angiogenesis: structure-function relationships and potential mechanisms. Journal of Cardiovascular Pharmacology. 48: 6-13. PMID 16954815 DOI: 10.1097/01.fjc.0000238591.90062.62  1
2006 Barth H, Schnober EK, Zhang F, Linhardt RJ, Depla E, Boson B, Cosset FL, Patel AH, Blum HE, Baumert TF. Viral and cellular determinants of the hepatitis C virus envelope-heparan sulfate interaction. Journal of Virology. 80: 10579-90. PMID 16928753 DOI: 10.1128/JVI.00941-06  1
2006 Turnbull JE, Linhardt RJ. Synthetic sugars enhance the functional glycomics toolkit. Nature Chemical Biology. 2: 449-50. PMID 16921352 DOI: 10.1038/nchembio0906-449  0.92
2006 Garg HG, Hales CA, Yu L, Butler M, Islam T, Xie J, Linhardt RJ. Increase in the growth inhibition of bovine pulmonary artery smooth muscle cells by an O-hexanoyl low-molecular-weight heparin derivative. Carbohydrate Research. 341: 2607-12. PMID 16920092 DOI: 10.1016/j.carres.2006.07.014  1
2006 Shao C, Zhang F, Kemp MM, Linhardt RJ, Waisman DM, Head JF, Seaton BA. Crystallographic analysis of calcium-dependent heparin binding to annexin A2. The Journal of Biological Chemistry. 281: 31689-95. PMID 16882661 DOI: 10.1074/jbc.M604502200  1
2006 Daniels B, Linhardt RJ, Zhang F, Mao W, Wice SM, Hiebert LM. In vivo antithrombotic synergy of oral heparin and arginine: endothelial thromboresistance without changes in coagulation parameters. Thrombosis and Haemostasis. 95: 865-72. PMID 16676079  1
2006 Murugesan S, Mousa S, Vijayaraghavan A, Ajayan PM, Linhardt RJ. Ionic liquid-derived blood-compatible composite membranes for kidney dialysis. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 79: 298-304. PMID 16637031 DOI: 10.1002/jbm.b.30542  1
2006 Sakai S, Akiyama H, Sato Y, Yoshioka Y, Linhardt RJ, Goda Y, Maitani T, Toida T. Chondroitin sulfate intake inhibits the IgE-mediated allergic response by down-regulating Th2 responses in mice. The Journal of Biological Chemistry. 281: 19872-80. PMID 16624819 DOI: 10.1074/jbc.M509058200  1
2006 Muñoz E, Xu D, Kemp M, Zhang F, Liu J, Linhardt RJ. Affinity, kinetic, and structural study of the interaction of 3-O-sulfotransferase isoform 1 with heparan sulfate. Biochemistry. 45: 5122-8. PMID 16618101 DOI: 10.1021/bi052403n  1
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