Robert J. Linhardt - Publications

Affiliations: 
1982-2003 Medicinal and Natural Products Chemistry University of Iowa, Iowa City, IA 
 2003- Biocatalysis and Metabolic Engineering Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Heparin
Website:
http://www-heparin.rpi.edu/main/people/view/1

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Year Citation  Score
2022 Lang K, Quichocho HB, Black SP, Bramson MTK, Linhardt RJ, Corr DT, Gross RA. Lipase-Catalyzed Poly(glycerol-1,8-octanediol-sebacate): Biomaterial Engineering by Combining Compositional and Crosslinking Variables. Biomacromolecules. PMID 35468284 DOI: 10.1021/acs.biomac.2c00198  0.784
2022 Zhao J, Liu X, Blayney A, Zhang Y, Gandy L, Mirsky PO, Smith N, Zhang F, Linhardt RJ, Chen J, Baines C, Loh SN, Wang C. Intrinsically Disordered N-terminal Domain (NTD) of p53 Interacts with Mitochondrial PTP Regulator Cyclophilin D. Journal of Molecular Biology. 434: 167552. PMID 35341741 DOI: 10.1016/j.jmb.2022.167552  0.63
2022 Shionoya K, Suzuki T, Takada M, Sato K, Onishi S, Dohmae N, Nishino K, Wada T, Linhardt RJ, Toida T, Higashi K. Comprehensive analysis of chondroitin sulfate and aggrecan in the head cartilage of bony fishes: Identification of proteoglycans in the head cartilage of sturgeon. International Journal of Biological Macromolecules. 208: 333-342. PMID 35339495 DOI: 10.1016/j.ijbiomac.2022.03.125  0.495
2022 Kim SB, Zoepfl M, Samanta P, Zhang F, Xia K, Thara R, Linhardt RJ, Doerksen RJ, McVoy MA, Pomin VH. Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties. The Journal of Biological Chemistry. 101856. PMID 35337800 DOI: 10.1016/j.jbc.2022.101856  0.498
2022 Ahat E, Song Y, Xia K, Reid W, Li J, Bui S, Zhang F, Linhardt RJ, Wang Y. GRASP depletion-mediated Golgi fragmentation impairs glycosaminoglycan synthesis, sulfation, and secretion. Cellular and Molecular Life Sciences : Cmls. 79: 199. PMID 35312866 DOI: 10.1007/s00018-022-04223-3  0.452
2022 Zhang Y, Liu P, Wang C, Zhang F, Linhardt RJ, Eliezer D, Li Q, Zhao J. Homogalacturonan from squash: Characterization and tau-binding pattern of a sulfated derivative. Carbohydrate Polymers. 285: 119250. PMID 35287864 DOI: 10.1016/j.carbpol.2022.119250  0.517
2022 Zhang F, He P, Rodrigues AL, Jeske W, Tandon R, Bates JT, Bierdeman MA, Fareed J, Dordick J, Linhardt RJ. Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate. Pharmaceuticals (Basel, Switzerland). 15. PMID 35215371 DOI: 10.3390/ph15020258  0.468
2022 Yu Y, Fu L, He P, Xia K, Varghese S, Wang H, Zhang F, Dordick J, Linhardt RJ. Chemobiocatalytic Synthesis of a Low-Molecular-Weight Heparin. Acs Chemical Biology. PMID 35201757 DOI: 10.1021/acschembio.1c00928  0.76
2022 Wu D, Chen S, Ye X, Zheng X, Ahmadi S, Hu W, Yu C, Cheng H, Linhardt RJ, Chen J. Enzyme-extracted raspberry pectin exhibits a high-branched structure and enhanced anti-inflammatory properties than hot acid-extracted pectin. Food Chemistry. 383: 132387. PMID 35182862 DOI: 10.1016/j.foodchem.2022.132387  0.478
2022 Clark GT, Yu Y, Urban CA, Fu G, Wang C, Zhang F, Linhardt RJ, Hurley JM. Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates. Plos Genetics. 18: e1009994. PMID 35143487 DOI: 10.1371/journal.pgen.1009994  0.635
2022 Janke JJ, Yu Y, Pomin VH, Zhao J, Wang C, Linhardt RJ, García AE. Characterization of Heparin's Conformational Ensemble by Molecular Dynamics Simulations and Nuclear Magnetic Resonance Spectroscopy. Journal of Chemical Theory and Computation. PMID 35108013 DOI: 10.1021/acs.jctc.1c00760  0.779
2022 Xiao F, Lian J, Tu S, Xie L, Li J, Zhang F, Linhardt RJ, Huang H, Zhong W. Metabolic Engineering of for High-Level Production of Chlorogenic Acid from Glucose. Acs Synthetic Biology. PMID 35107250 DOI: 10.1021/acssynbio.1c00487  0.632
2022 Ren S, Fraser K, Kuo L, Chauhan N, Adrian AT, Zhang F, Linhardt RJ, Kwon PS, Wang X. Designer DNA nanostructures for viral inhibition. Nature Protocols. PMID 35013618 DOI: 10.1038/s41596-021-00641-y  0.491
2022 Fu L, Linhardt RJ. One-Pot Enzymatic Synthesis of Heparin from N-Sulfoheparosan. Methods in Molecular Biology (Clifton, N.J.). 2303: 3-11. PMID 34626365 DOI: 10.1007/978-1-0716-1398-6_1  0.375
2021 Song Y, He P, Rodrigues AL, Datta P, Tandon R, Bates JT, Bierdeman MA, Chen C, Dordick J, Zhang F, Linhardt RJ. Anti-SARS-CoV-2 Activity of Rhamnan Sulfate from . Marine Drugs. 19. PMID 34940684 DOI: 10.3390/md19120685  0.615
2021 Ning Z, Lang K, Xia K, Linhardt RJ, Gross RA. Lipase-Catalyzed Synthesis and Characterization of Poly(glycerol sebacate). Biomacromolecules. PMID 34936341 DOI: 10.1021/acs.biomac.1c01351  0.796
2021 Bauer S, Zhang F, Linhardt RJ. Implications of Glycosaminoglycans on Viral Zoonotic Diseases. Diseases (Basel, Switzerland). 9. PMID 34842642 DOI: 10.3390/diseases9040085  0.395
2021 Zhang W, Wu W, Bao Y, Yan X, Zhang F, Linhardt RJ, Jin W, Mao G. Comparative study on the mechanisms of anti-lung cancer activities of three sulfated galactofucans. Food & Function. PMID 34590105 DOI: 10.1039/d1fo02062e  0.466
2021 Dwivedi R, Samanta P, Sharma P, Zhang F, Mishra SK, Kucheryavy P, Kim SB, Aderibigbe AO, Linhardt RJ, Tandon R, Doerksen RJ, Pomin VH. Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection. The Journal of Biological Chemistry. 101207. PMID 34537241 DOI: 10.1016/j.jbc.2021.101207  0.464
2021 Datta P, Zhang F, Dordick JS, Linhardt RJ. Platelet factor 4 polyanion immune complexes: heparin induced thrombocytopenia and vaccine-induced immune thrombotic thrombocytopenia. Thrombosis Journal. 19: 66. PMID 34526009 DOI: 10.1186/s12959-021-00318-2  0.561
2021 Jin W, Zhang F, Linhardt RJ. Glycosaminoglycans in Neurodegenerative Diseases. Advances in Experimental Medicine and Biology. 1325: 189-204. PMID 34495536 DOI: 10.1007/978-3-030-70115-4_9  0.469
2021 Song Y, Zhang F, Linhardt RJ. Glycosaminoglycans. Advances in Experimental Medicine and Biology. 1325: 103-116. PMID 34495531 DOI: 10.1007/978-3-030-70115-4_4  0.415
2021 Pomin VH, Mahdi F, Jin W, Zhang F, Linhardt RJ, Paris JJ. Red Algal Sulfated Galactan Binds and Protects Neural Cells from HIV-1 gp120 and Tat. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451811 DOI: 10.3390/ph14080714  0.431
2021 Sordini L, Silva JC, Garrudo FFF, Rodrigues CAV, Marques AC, Linhardt RJ, Cabral JMS, Morgado J, Ferreira FC. PEDOT:PSS-Coated Polybenzimidazole Electroconductive Nanofibers for Biomedical Applications. Polymers. 13. PMID 34451324 DOI: 10.3390/polym13162786  0.738
2021 Chengxiao Y, Dongmei W, Kai Z, Hou L, Xiao H, Ding T, Liu D, Ye X, Linhardt RJ, Chen S. Challenges of pectic polysaccharides as a prebiotic from the perspective of fermentation characteristics and anti-colitis activity. Carbohydrate Polymers. 270: 118377. PMID 34364621 DOI: 10.1016/j.carbpol.2021.118377  0.69
2021 Mitra D, Hasan MH, Bates JT, Bierdeman MA, Ederer DR, Parmar RC, Fassero LA, Liang Q, Qiu H, Tiwari V, Zhang F, Linhardt RJ, Sharp JS, Wang L, Tandon R. The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells. Plos Pathogens. 17: e1009803. PMID 34352038 DOI: 10.1371/journal.ppat.1009803  0.453
2021 Garrudo FFF, Nogueira DES, Rodrigues CAV, Ferreira FA, Paradiso P, Colaço R, Marques AC, Cabral JMS, Morgado J, Linhardt RJ, Ferreira FC. Electrical stimulation of neural-differentiating iPSCs on novel coaxial electroconductive nanofibers. Biomaterials Science. PMID 34223566 DOI: 10.1039/d1bm00503k  0.666
2021 Yue J, Jin W, Yang H, Faulkner J, Song X, Qiu H, Teng M, Azadi P, Zhang F, Linhardt RJ, Wang L. Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer. Frontiers in Molecular Biosciences. 8: 649575. PMID 34179075 DOI: 10.3389/fmolb.2021.649575  0.447
2021 Mah D, Zhao J, Liu X, Zhang F, Liu J, Wang L, Linhardt R, Wang C. The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology. Frontiers in Molecular Biosciences. 8: 671458. PMID 34095227 DOI: 10.3389/fmolb.2021.671458  0.621
2021 Zheng J, Li B, Ji Y, Chen Y, Lv X, Zhang X, Linhardt RJ. Prolonged release and shelf-life of anticoagulant sulfated polysaccharides encapsulated with ZIF-8. International Journal of Biological Macromolecules. PMID 33984382 DOI: 10.1016/j.ijbiomac.2021.05.007  0.5
2021 Song Y, Qu Y, Cao X, Zhang W, Zhang F, Linhardt RJ, Yang Q. Cultivation of fractionated cells from a bioactive-alkaloid-bearing marine sponge Axinella sp. In Vitro Cellular & Developmental Biology. Animal. PMID 33948851 DOI: 10.1007/s11626-021-00578-2  0.433
2021 Shute T, Amiel E, Alam N, Yates JL, Mohrs K, Dudley E, Salas B, Mesa C, Serrata A, Angel D, Vincent BK, Weyers A, Lanthier PA, Vomhof-Dekrey E, Fromme R, ... ... Linhardt RJ, et al. Glycolipid-Containing Nanoparticle Vaccine Engages Invariant NKT Cells to Enhance Humoral Protection against Systemic Bacterial Infection but Abrogates T-Independent Vaccine Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 33811104 DOI: 10.4049/jimmunol.2001283  0.769
2021 Yan L, Song Y, Xia K, He P, Zhang F, Chen S, Pouliot R, Weiss DJ, Tandon R, Bates JT, Ederer DR, Mitra D, Sharma P, Davis A, Linhardt RJ. Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus. Carbohydrate Polymers. 260: 117797. PMID 33712145 DOI: 10.1016/j.carbpol.2021.117797  0.664
2021 Xia K, Hagan JT, Fu L, Sheetz BS, Bhattacharya S, Zhang F, Dwyer JR, Linhardt RJ. Synthetic heparan sulfate standards and machine learning facilitate the development of solid-state nanopore analysis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33688052 DOI: 10.1073/pnas.2022806118  0.637
2021 Sordini L, Garrudo FFF, Rodrigues CAV, Linhardt RJ, Cabral JMS, Ferreira FC, Morgado J. Effect of Electrical Stimulation Conditions on Neural Stem Cells Differentiation on Cross-Linked PEDOT:PSS Films. Frontiers in Bioengineering and Biotechnology. 9: 591838. PMID 33681153 DOI: 10.3389/fbioe.2021.591838  0.664
2021 Badri A, Williams A, Awofiranye A, Datta P, Xia K, He W, Fraser K, Dordick JS, Linhardt RJ, Koffas MAG. Complete biosynthesis of a sulfated chondroitin in Escherichia coli. Nature Communications. 12: 1389. PMID 33654100 DOI: 10.1038/s41467-021-21692-5  0.687
2021 Wu D, Ye X, Linhardt RJ, Liu X, Zhu K, Yu C, Ding T, Liu D, He Q, Chen S. Dietary pectic substances enhance gut health by its polycomponent: A review. Comprehensive Reviews in Food Science and Food Safety. PMID 33594822 DOI: 10.1111/1541-4337.12723  0.466
2021 Xu H, Shen B, Qiao M, Linhardt RJ, Zhang X. Recent advances on the one-pot synthesis to assemble size-controlled glycans and glycoconjugates and polysaccharides. Carbohydrate Polymers. 258: 117672. PMID 33593549 DOI: 10.1016/j.carbpol.2021.117672  0.319
2021 Wang P, Zhao J, Hossaini Nasr S, Otieno SA, Zhang F, Qiang W, Linhardt RJ, Huang X. Probing Amyloid β Interactions with Synthetic Heparan Sulfate Oligosaccharides. Acs Chemical Biology. PMID 33592143 DOI: 10.1021/acschembio.0c00904  0.483
2021 Baytas SN, Varghese SS, Jin W, Yu Y, He P, Douaisi M, Zhang F, Brodfuehrer P, Xia K, Dordick JS, Linhardt RJ. Preparation of Low Molecular Weight Heparin from a Remodeled Bovine Intestinal Heparin. Journal of Medicinal Chemistry. PMID 33586962 DOI: 10.1021/acs.jmedchem.0c02019  0.8
2021 Giubertoni G, Pérez de Alba Ortíz A, Bano F, Zhang X, Linhardt RJ, Green DE, DeAngelis PL, Koenderink GH, Richter RP, Ensing B, Bakker HJ. Strong Reduction of the Chain Rigidity of Hyaluronan by Selective Binding of Ca Ions. Macromolecules. 54: 1137-1146. PMID 33583956 DOI: 10.1021/acs.macromol.0c02242  0.309
2021 Bauer S, Jin W, Zhang F, Linhardt RJ. The Application of Seaweed Polysaccharides and Their Derived Products with Potential for the Treatment of Alzheimer's Disease. Marine Drugs. 19. PMID 33557077 DOI: 10.3390/md19020089  0.397
2021 Garrudo FFF, Mikael PE, Rodrigues CAV, Udangawa RW, Paradiso P, Chapman CA, Hoffman P, Colaço R, Cabral JMS, Morgado J, Linhardt RJ, Ferreira FC. Polyaniline-polycaprolactone fibers for neural applications: Electroconductivity enhanced by pseudo-doping. Materials Science & Engineering. C, Materials For Biological Applications. 120: 111680. PMID 33545842 DOI: 10.1016/j.msec.2020.111680  0.776
2021 Pan L, Cai C, Liu C, Liu D, Li G, Linhardt RJ, Yu G. Recent progress and advanced technology in carbohydrate-based drug development. Current Opinion in Biotechnology. 69: 191-198. PMID 33530023 DOI: 10.1016/j.copbio.2020.12.023  0.774
2021 Datta P, Fu L, Brodfuerer P, Dordick JS, Linhardt RJ. High density fermentation of probiotic E. coli Nissle 1917 towards heparosan production, characterization, and modification. Applied Microbiology and Biotechnology. PMID 33481068 DOI: 10.1007/s00253-020-11079-9  0.586
2021 Zheng L, Zhu X, Yang K, Zhu M, Farooqi AA, Kang D, Sun M, Xu Y, Lin X, Feng Y, Liang F, Zhang F, Linhardt RJ. Correction: Zheng, L., et al. PBN11-8, a Cytotoxic Polypeptide Purified from Marine , Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. 2018, , 1043. Polymers. 13. PMID 33466568 DOI: 10.3390/polym13010166  0.744
2021 Garrudo FFF, Mikael PE, Xia K, Silva JC, Ouyang Y, Chapman CA, Hoffman PR, Yu Y, Han X, Rodrigues CAV, Cabral JMS, Morgado J, Ferreira FC, Linhardt RJ. The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells. Biochimie. PMID 33422570 DOI: 10.1016/j.biochi.2021.01.001  0.79
2021 Zhang X, Hashimoto JG, Han X, Zhang F, Linhardt RJ, Guizzetti M. Characterization of Glycosaminoglycan Disaccharide Composition in Astrocyte Primary Cultures and the Cortex of Neonatal Rats. Neurochemical Research. PMID 33398638 DOI: 10.1007/s11064-020-03195-9  0.426
2021 Li J, Li S, Xie L, Chen G, Shen M, Pan F, Shu M, Yang Y, Jiao Y, Zhang F, Linhardt RJ, Zhong W. Additional role of nicotinic acid hydroxylase for the transformation of 3-succinoyl-pyridine by sp. JY-Q. Applied and Environmental Microbiology. PMID 33397698 DOI: 10.1128/AEM.02740-20  0.623
2021 Chen Y, Wang T, Zhang X, Zhang F, Linhardt RJ. Structural and immunological studies on the polysaccharide from spores of a medicinal entomogenous fungus Paecilomyces cicadae. Carbohydrate Polymers. 254: 117462. PMID 33357921 DOI: 10.1016/j.carbpol.2020.117462  0.608
2021 Chazeirat T, Denamur S, Bojarski KK, Andrault PM, Sizaret D, Zhang F, Saidi A, Tardieu M, Linhardt RJ, Labarthe F, Brömme D, Samsonov SA, Lalmanach G, Lecaille F. The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V. Carbohydrate Polymers. 253: 117261. PMID 33278943 DOI: 10.1016/j.carbpol.2020.117261  0.424
2021 Chen J, Cheng H, Zhi Z, Zhang H, Linhardt RJ, Zhang F, Chen S, Ye X. Extraction temperature is a decisive factor for the properties of pectin Food Hydrocolloids. 112: 106160. DOI: 10.1016/J.Foodhyd.2020.106160  0.629
2020 Sheng A, Chen Q, Yu M, Xiao R, Zhang T, Wang Z, Linhardt RJ, Sun X, Jin L, Chi L. Coupling Liquid Chromatography and Tandem Mass Spectrometry to Electrophoresis for In-Depth Analysis of Glycosaminoglycan Drugs: Heparin and the Multicomponent Sulodexide. Analytical Chemistry. PMID 33369405 DOI: 10.1021/acs.analchem.0c03330  0.803
2020 Kim SY, Zhang F, Harris DA, Linhardt RJ. Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance. Frontiers in Molecular Biosciences. 7: 594497. PMID 33324681 DOI: 10.3389/fmolb.2020.594497  0.555
2020 Lang K, Sánchez-Leija RJ, Gross RA, Linhardt RJ. Review on the Impact of Polyols on the Properties of Bio-Based Polyesters. Polymers. 12. PMID 33322728 DOI: 10.3390/polym12122969  0.783
2020 Wang F, Li Y, Yu L, Zhu J, Zhang F, Linhardt RJ. Amphiphilic mPEG-Modified Oligo-Phenylalanine Nanoparticles Chemoenzymatically Synthesized via Papain. Acs Omega. 5: 30336-30347. PMID 33251469 DOI: 10.1021/acsomega.0c05076  0.398
2020 Lin L, Li B, Han X, Zhang F, Zhang X, Linhardt RJ. A rolling circle amplification based platform for ultrasensitive detection of heparin. The Analyst. PMID 33226386 DOI: 10.1039/d0an02061c  0.645
2020 Walker RG, Kattamuri C, Goebel EJ, Zhang F, Hammel M, Tainer JA, Linhardt RJ, Thompson TB. Heparin-mediated dimerization of follistatin. Experimental Biology and Medicine (Maywood, N.J.). 1535370220966296. PMID 33197333 DOI: 10.1177/1535370220966296  0.451
2020 Amores de Sousa MC, Rodrigues CAV, Ferreira IAF, Diogo MM, Linhardt RJ, Cabral JMS, Ferreira FC. Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation. Frontiers in Bioengineering and Biotechnology. 8: 580135. PMID 33195141 DOI: 10.3389/fbioe.2020.580135  0.538
2020 Huang C, Shan L, Chen Z, He Z, Li J, Yang Y, Shu M, Pan F, Jiao Y, Zhang F, Linhardt RJ, Zhong W. Differential effect of homologous NicR2A/NicR2Bs and endogenous ectopic strong promoters on nicotine metabolism in sp. JY-Q. Applied and Environmental Microbiology. PMID 33187996 DOI: 10.1128/AEM.02457-20  0.624
2020 Tandon R, Sharp JS, Zhang F, Pomin VH, Ashpole NM, Mitra D, McCandless MG, Jin W, Liu H, Sharma P, Linhardt RJ. Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives. Journal of Virology. PMID 33173010 DOI: 10.1128/JVI.01987-20  0.462
2020 Yan L, Fu L, Xia K, Chen S, Zhang F, Dordick JS, Linhardt RJ. A Revised Structure for the Glycolipid Terminus of K5 Heparosan Capsular Polysaccharide. Biomolecules. 10. PMID 33171953 DOI: 10.3390/biom10111516  0.713
2020 Qiao M, Li B, Ji Y, Lin L, Linhardt R, Zhang X. Synthesis of selected unnatural sugar nucleotides for biotechnological applications. Critical Reviews in Biotechnology. 1-16. PMID 33153306 DOI: 10.1080/07388551.2020.1844623  0.544
2020 Ko K, Suzuki T, Ishikawa R, Hattori N, Ito R, Umehara K, Furihata T, Dohmae N, Linhardt RJ, Igarashi K, Toida T, Higashi K. Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure. The Journal of Biological Chemistry. PMID 33127645 DOI: 10.1074/jbc.RA120.015105  0.48
2020 Liu X, Zhao Z, Dong G, Li Y, Peng F, Liu C, Zhang F, Linhardt RJ, Yang Y, Bai Z. Identification, repair and characterization of a benzyl alcohol-inducible promoter for recombinant proteins overexpression in Corynebacterium glutamicum. Enzyme and Microbial Technology. 141: 109651. PMID 33051010 DOI: 10.1016/J.Enzmictec.2020.109651  0.494
2020 Ito D, Ge D, Kogure N, Manaka H, Terui Y, Takayama H, Linhardt RJ, Toida T, Higashi K. Poly-ion complex (PIC) formation of heparin and polyamines: PIC with tetrakis (3-aminopropyl) ammonium allows sustained release of heparin. Heliyon. 6: e05168. PMID 33043161 DOI: 10.1016/j.heliyon.2020.e05168  0.527
2020 Datta P, Yan L, Awofiranye A, Dordick JS, Linhardt RJ. Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers. Biotechnology Journal. e2000336. PMID 33006278 DOI: 10.1002/biot.202000336  0.502
2020 Li J, Shen M, Chen Z, Pan F, Yang Y, Shu M, Chen G, Jiao Y, Zhang F, Linhardt RJ, Zhong W. Expression and functional identification of two homologous nicotine dehydrogenases, NicA2 and Nox, from Pseudomonas sp. JY-Q. Protein Expression and Purification. 105767. PMID 32987121 DOI: 10.1016/j.pep.2020.105767  0.638
2020 Jin W, Zhang W, Mitra D, McCandless MG, Sharma P, Tandon R, Zhang F, Linhardt RJ. The structure-activity relationship of the interactions of SARS-CoV-2 spike glycoproteins with glucuronomannan and sulfated galactofucan from Saccharina japonica. International Journal of Biological Macromolecules. PMID 32979436 DOI: 10.1016/j.ijbiomac.2020.09.184  0.478
2020 Miller MC, Cai C, Wichapong K, Bhaduri S, Pohl NLB, Linhardt RJ, Gabius HJ, Mayo KH. Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides. Scientific Reports. 10: 15708. PMID 32973213 DOI: 10.1038/s41598-020-72645-9  0.496
2020 Ferencz B, Condac E, Poudel N, Munteanu MC, Sivasami P, Choudhury B, Naidu NN, Zhang F, Breshears M, Linhardt RJ, Hinsdale ME. Xylosyltransferase 2 deficiency and organ homeostasis. Glycoconjugate Journal. PMID 32965647 DOI: 10.1007/s10719-020-09945-9  0.422
2020 Baytas SN, Linhardt RJ. Advances in the preparation and synthesis of heparin and related products. Drug Discovery Today. PMID 32947045 DOI: 10.1016/J.Drudis.2020.09.011  0.75
2020 Jin W, He X, Zhu J, Fang Q, Wei B, Sun J, Zhang W, Zhang Z, Zhang F, Linhardt RJ, Wang H, Zhong W. Inhibition of glucuronomannan hexamer on the proliferation of lung cancer through binding with immunoglobulin G. Carbohydrate Polymers. 248: 116785. PMID 32919573 DOI: 10.1016/J.Carbpol.2020.116785  0.652
2020 Cui JY, Zhang F, Nierzwicki L, Palermo G, Linhardt RJ, Lisi GP. Mapping the Structural and Dynamic Determinants of pH-Sensitive Heparin Binding to Granulocyte Macrophage Colony Stimulating Factor. Biochemistry. PMID 32897051 DOI: 10.1021/Acs.Biochem.0C00538  0.523
2020 Qiao M, Lin L, Xia K, Li J, Zhang X, Linhardt RJ. Recent advances in biotechnology for heparin and heparan sulfate analysis. Talanta. 219: 121270. PMID 32887160 DOI: 10.1016/J.Talanta.2020.121270  0.707
2020 Yan L, Zhu M, Wang D, Tao W, Liu D, Zhang F, Linhardt RJ, Ye X, Chen S. Oral Administration of Fucosylated Chondroitin Sulfate Oligomers in Gastro-Resistant Microcapsules Exhibits a Safe Antithrombotic Activity. Thrombosis and Haemostasis. PMID 32862408 DOI: 10.1055/S-0040-1714738  0.623
2020 Bhattacharya S, Kim D, Gopal S, Tice A, Lang K, Dordick JS, Plawsky JL, Linhardt RJ. Antimicrobial effects of positively charged, conductive electrospun polymer fibers. Materials Science & Engineering. C, Materials For Biological Applications. 116: 111247. PMID 32806282 DOI: 10.1016/J.Msec.2020.111247  0.77
2020 Awofiranye AE, Baytas SN, Xia K, Badri A, He W, Varki A, Koffas M, Linhardt RJ. N-glycolyl chondroitin synthesis using metabolically engineered E. coli. Amb Express. 10: 144. PMID 32803432 DOI: 10.1186/S13568-020-01084-6  0.789
2020 Yan L, Wang D, Yu Y, Zhang F, Ye X, Linhardt RJ, Chen S. Fucosylated Chondroitin Sulfate 9-18 Oligomers Exhibit Molecular Size-Independent Antithrombotic Activity while Circulating in the Blood. Acs Chemical Biology. PMID 32786291 DOI: 10.1021/Acschembio.0C00439  0.761
2020 Crouch LI, Liberato MV, Urbanowicz PA, Baslé A, Lamb CA, Stewart CJ, Cooke K, Doona M, Needham S, Brady RR, Berrington JE, Madunic K, Wuhrer M, Chater P, Pearson JP, ... ... Linhardt RJ, et al. Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown. Nature Communications. 11: 4017. PMID 32782292 DOI: 10.1038/S41467-020-17847-5  0.516
2020 Yan L, Brodfueher P, Fu L, Zhang F, Chen S, Dordick JS, Linhardt RJ. Chemical O-sulfation of N-sulfoheparosan: a route to rare N-sulfo-3-O-sulfoglucosamine and 2-O-sulfoglucuronic acid. Glycoconjugate Journal. PMID 32778986 DOI: 10.1007/S10719-020-09939-7  0.689
2020 Liu T, Li J, Qiu L, Zhang F, Linhardt RJ, Zhong W. Combined genomic and transcriptomic analysis of Dibutyl phthalate metabolic pathway in Arthrobacter sp. ZJUTW. Biotechnology and Bioengineering. PMID 32740909 DOI: 10.1002/Bit.27524  0.65
2020 Olmsted ZT, Stigliano C, Badri A, Zhang F, Williams A, Koffas MAG, Xie Y, Linhardt RJ, Cibelli J, Horner PJ, Paluh JL. Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery. Scientific Reports. 10: 12939. PMID 32737387 DOI: 10.1038/S41598-020-69274-7  0.473
2020 Li J, Sparkenbaugh EM, Su G, Zhang F, Xu Y, Xia K, He P, Baytas S, Pechauer S, Padmanabhan A, Linhardt RJ, Pawlinski R, Liu J. Enzymatic Synthesis of Chondroitin Sulfate E to Attenuate Bacteria Lipopolysaccharide-Induced Organ Damage. Acs Central Science. 6: 1199-1207. PMID 32724854 DOI: 10.1021/Acscentsci.0C00712  0.778
2020 Yu Y, Zhang F, Renois-Predelus G, Amster IJ, Linhardt RJ. Filter-entrapment enrichment pull-down assay for glycosaminoglycan structural characterization and protein interaction. Carbohydrate Polymers. 245: 116623. PMID 32718661 DOI: 10.1016/J.Carbpol.2020.116623  0.716
2020 Wu D, Zheng J, Hu W, Zheng X, He Q, Linhardt RJ, Ye X, Chen S. Structure-activity relationship of Citrus segment membrane RG-I pectin against Galectin-3: The galactan is not the only important factor. Carbohydrate Polymers. 245: 116526. PMID 32718630 DOI: 10.1016/J.Carbpol.2020.116526  0.526
2020 Kwon PS, Oh H, Kwon SJ, Jin W, Zhang F, Fraser K, Hong JJ, Linhardt RJ, Dordick JS. Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro. Cell Discovery. 6: 50. PMID 32714563 DOI: 10.1038/S41421-020-00192-8  0.484
2020 Horton M, Su G, Yi L, Wang Z, Xu Y, Pagadala V, Zhang F, Zaharoff DA, Pearce K, Linhardt RJ, Liu J. Construction of heparan sulfate microarray for investigating the binding of specific saccharide sequences to proteins. Glycobiology. PMID 32681173 DOI: 10.1093/Glycob/Cwaa068  0.58
2020 Wu J, Tian Y, Han L, Liu C, Sun T, Li L, Yu Y, Lamichhane B, D'Souza RN, Millar SE, Krumlauf R, Ornitz DM, Feng JQ, Klein O, Zhao H, ... ... Linhardt RJ, et al. FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling. Bmc Biology. 18: 87. PMID 32664967 DOI: 10.1186/S12915-020-00813-4  0.683
2020 Kim SY, Jin W, Sood A, Montgomery DW, Grant OC, Fuster MM, Fu L, Dordick JS, Woods RJ, Zhang F, Linhardt RJ. Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions. Antiviral Research. 104873. PMID 32653452 DOI: 10.1016/J.Antiviral.2020.104873  0.642
2020 Jin W, He X, Wu W, Bao Y, Wang S, Cai M, Zhang W, Wang C, Zhang F, Linhardt RJ, Mao G, Zhong W. Structural analysis of a glucoglucuronan derived from laminarin and the mechanisms of its anti-lung cancer activity. International Journal of Biological Macromolecules. PMID 32653371 DOI: 10.1016/J.Ijbiomac.2020.07.069  0.684
2020 Zhu K, Mao G, Wu D, Yu C, Xiao H, Ye X, Linhardt RJ, Orfila C, Chen S. Highly Branched RG-I Domain Enrichment are Indispensable for Pectin Mitigating Against High-Fat Diet-Induced Obesity. Journal of Agricultural and Food Chemistry. PMID 32633953 DOI: 10.1021/Acs.Jafc.0C02654  0.472
2020 Song Y, Zhang F, Linhardt RJ. Analysis of the Glycosaminoglycan Chains of Proteoglycans. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155420937154. PMID 32623943 DOI: 10.1369/0022155420937154  0.528
2020 Jin W, Fang Q, Jiang D, Li T, Wei B, Sun J, Zhang W, Zhang Z, Zhang F, Linhardt RJ, Wang H, Zhong W. Structural characteristics and anti-complement activities of polysaccharides from Sargassum hemiphyllum. Glycoconjugate Journal. PMID 32617856 DOI: 10.1007/S10719-020-09928-W  0.682
2020 Datta P, Fu L, He W, Koffas MAG, Dordick JS, Linhardt RJ. Expression of enzymes for 3'-phosphoadenosine-5'-phosphosulfate (PAPS) biosynthesis and their preparation for PAPS synthesis and regeneration. Applied Microbiology and Biotechnology. PMID 32601738 DOI: 10.1007/S00253-020-10709-6  0.672
2020 Bhattacharyya S, Feferman L, Han X, Xia K, Zhang F, Linhardt RJ, Tobacman JK. Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity. Oncotarget. 11: 2327-2344. PMID 32595831 DOI: 10.18632/Oncotarget.27634  0.606
2020 Vaidyanathan D, Xia K, Yu Y, Linhardt RJ, Dordick JS. Polysaccharide Sequence Influences the Specificity and Catalytic Activity of Glucuronyl C5-Epimerase. Biochemistry. PMID 32579846 DOI: 10.1021/Acs.Biochem.0C00419  0.714
2020 Tandon R, Sharp JS, Zhang F, Pomin VH, Ashpole NM, Mitra D, Jin W, Liu H, Sharma P, Linhardt RJ. Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives. Biorxiv : the Preprint Server For Biology. PMID 32577638 DOI: 10.1101/2020.06.08.140236  0.454
2020 Yang Y, Zheng Y, Wang P, Li X, Zhan C, Linhardt RJ, Zhang F, Liu X, Zhan J, Bai Z. Characterization and application of a putative transcription factor (SUT2) in Pichia pastoris. Molecular Genetics and Genomics : Mgg. PMID 32566991 DOI: 10.1007/S00438-020-01697-3  0.49
2020 Lang K, Bhattacharya S, Ning Z, Sanchez-Leija RJ, Bramson MTK, Centore R, Corr DT, Linhardt RJ, Gross RA. Enzymatic polymerization of poly(glycerol-1,8-octanediol-sebacate): versatile PGS analogs that form mono-component biodegradable fiber scaffolds. Biomacromolecules. PMID 32559083 DOI: 10.1021/Acs.Biomac.0C00641  0.786
2020 Yu Y, Bruzdoski K, Kostousov V, Hensch L, Hui SK, Siddiqui F, Farooqui A, Kouta A, Zhang F, Fareed J, Teruya J, Linhardt RJ. Structural characterization of a clinically described heparin-like substance in plasma causing bleeding. Carbohydrate Polymers. 244: 116443. PMID 32536393 DOI: 10.1016/J.Carbpol.2020.116443  0.673
2020 Jin W, Jiang D, Zhang W, Wang C, Xia K, Zhang F, Linhardt RJ. Interactions of fibroblast growth factors with sulfated galactofucan from Saccharina japonica. International Journal of Biological Macromolecules. PMID 32464202 DOI: 10.1016/J.Ijbiomac.2020.05.183  0.642
2020 LaRiviere WB, Liao S, McMurtry SA, Oshima K, Han X, Zhang F, Yan S, Haeger SM, Ransom M, Bastarache JA, Linhardt RJ, Schmidt EP, Yang Y. Alveolar heparan sulfate shedding impedes recovery from bleomycin-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32320623 DOI: 10.1152/Ajplung.00063.2020  0.478
2020 Jin W, He X, Long L, Fang Q, Wei B, Sun J, Zhang W, Wang H, Zhang F, Linhardt RJ. Structural characterization and anti-lung cancer activity of a sulfated glucurono-xylo-rhamnan from Enteromorpha prolifera. Carbohydrate Polymers. 237: 116143. PMID 32241440 DOI: 10.1016/J.Carbpol.2020.116143  0.511
2020 Yan L, Xia K, Yu Y, Miliakos A, Chaturvedi S, Zhang F, Chen S, Chaturvedi V, Linhardt RJ. Unique cell surface mannan of yeast pathogen Candida auris with selective binding to IgG. Acs Infectious Diseases. PMID 32233507 DOI: 10.1021/Acsinfecdis.9B00450  0.777
2020 Silva JC, Carvalho MS, Xia K, Cabral JMS, da Silva CL, Ferreira FC, Vashishth D, Linhardt RJ. Glycosaminoglycan disaccharide compositional analysis of cell-derived extracellular matrices using liquid chromatography-tandem mass spectrometry. Methods in Cell Biology. 156: 85-106. PMID 32222228 DOI: 10.1016/Bs.Mcb.2019.11.017  0.756
2020 Arnold K, Xu Y, Sparkenbaugh EM, Li M, Han X, Zhang X, Xia K, Piegore M, Zhang F, Zhang X, Henderson M, Pagadala V, Su G, Tan L, Park PW, ... ... Linhardt RJ, et al. Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure. Science Translational Medicine. 12. PMID 32188725 DOI: 10.1126/Scitranslmed.Aav8075  0.677
2020 Shao Y, Wang Y, Zhao R, Chen J, Zhang F, Linhardt RJ, Zhong W. Biotechnology progress for removal of indoor gaseous formaldehyde. Applied Microbiology and Biotechnology. PMID 32172323 DOI: 10.1007/S00253-020-10514-1  0.657
2020 Carvalho MS, Silva JC, Hoff CM, Cabral JMS, Linhardt RJ, da Silva CL, Vashishth D. Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells. Journal of Cellular Physiology. PMID 32162324 DOI: 10.1002/Jcp.29653  0.523
2020 Liang L, Liu G, Zhang F, Li Q, Linhardt RJ. Digestibility of squash polysaccharide under simulated salivary, gastric and intestinal conditions and its impact on short-chain fatty acid production in type-2 diabetic rats. Carbohydrate Polymers. 235: 115904. PMID 32122473 DOI: 10.1016/J.Carbpol.2020.115904  0.491
2020 Moura CS, Silva JC, Faria S, Fernandes PR, da Silva CL, Cabral JMS, Linhardt R, Bártolo PJ, Ferreira FC. Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation. Journal of Bioscience and Bioengineering. PMID 32107152 DOI: 10.1016/J.Jbiosc.2020.01.004  0.695
2020 Zhou S, Rahman A, Li J, Wei C, Chen J, Linhardt RJ, Ye X, Chen S. Extraction Methods Affect the Structure of Goji () Polysaccharides. Molecules (Basel, Switzerland). 25. PMID 32093113 DOI: 10.3390/Molecules25040936  0.531
2020 Li J, Qiao M, Ji Y, Lin L, Zhang X, Linhardt RJ. Chemical, enzymatic and biological synthesis of hyaluronic acids. International Journal of Biological Macromolecules. PMID 32088231 DOI: 10.1016/J.Ijbiomac.2020.02.214  0.596
2020 Silva JC, Han X, Silva TP, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ. Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow-/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia. Glycoconjugate Journal. PMID 32086666 DOI: 10.1007/S10719-020-09911-5  0.788
2020 Zhang N, Li G, Li S, Cai C, Zhang F, Linhardt RJ, Yu G. Mass spectrometric evidence for the mechanism of free-radical depolymerization of various types of glycosaminoglycans. Carbohydrate Polymers. 233: 115847. PMID 32059898 DOI: 10.1016/J.Carbpol.2020.115847  0.801
2020 Lu J, He R, Sun P, Zhang F, Linhardt RJ, Zhang A. Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review. International Journal of Biological Macromolecules. PMID 32035956 DOI: 10.1016/J.Ijbiomac.2020.02.035  0.786
2020 Jin W, Tang H, Zhang J, Wei B, Sun J, Zhang W, Zhang F, Wang H, Linhardt RJ, Zhong W. Structural analysis of a novel sulfated galacto-fuco-xylo-glucurono-mannan from Sargassum fusiforme and its anti-lung cancer activity. International Journal of Biological Macromolecules. PMID 32004605 DOI: 10.1016/J.Ijbiomac.2020.01.275  0.68
2020 Wen Y, Wen P, Hu TG, Linhardt RJ, Zong MH, Wu H, Chen ZY. Encapsulation of phycocyanin by prebiotics and polysaccharides-based electrospun fibers and improved colon cancer prevention effects. International Journal of Biological Macromolecules. PMID 31981665 DOI: 10.1016/J.Ijbiomac.2020.01.189  0.382
2020 Qiu H, Jin L, Chen J, Shi M, Shi F, Wang M, Li D, Xu X, Su X, Yin X, Li W, Zhou X, Linhardt RJ, Wang Z, Chi L, et al. Comprehensive Glycomic Analysis Reveals that Human Serum Albumin Glycation Specifically Affects the Pharmacokinetics and Efficacy of Different Anticoagulant Drugs in Diabetes. Diabetes. PMID 31974145 DOI: 10.2337/Db19-0738  0.77
2020 Lin YP, Yu Y, Marcinkiewicz AL, Lederman P, Hart TM, Zhang F, Linhardt RJ. Non-anticoagulant heparin as a pre-exposure prophylaxis prevents Lyme disease infection. Acs Infectious Diseases. PMID 31961652 DOI: 10.1021/Acsinfecdis.9B00425  0.688
2020 Silva JC, Carvalho MS, Udangawa RN, Moura CS, Cabral JMS, L da Silva C, Ferreira FC, Vashishth D, Linhardt RJ. Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient-tailored bone tissue engineering approach. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 31916699 DOI: 10.1002/Jbm.B.34554  0.685
2020 Lin L, Qiao M, Zhang X, Linhardt RJ. Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development. Carbohydrate Polymers. 230: 115643. PMID 31887910 DOI: 10.1016/J.Carbpol.2019.115643  0.597
2020 Liang L, Liu G, Yu G, Zhang F, Linhardt RJ, Li Q. Urinary metabolomics analysis reveals the anti-diabetic effect of stachyose in high-fat diet/streptozotocin-induced type 2 diabetic rats. Carbohydrate Polymers. 229: 115534. PMID 31826396 DOI: 10.1016/J.Carbpol.2019.115534  0.615
2020 Silva JC, Udangawa RN, Chen J, Mancinelli CD, Garrudo FFF, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ. Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering. Materials Science & Engineering. C, Materials For Biological Applications. 107: 110291. PMID 31761240 DOI: 10.1016/J.Msec.2019.110291  0.78
2020 Silva JC, Moura CS, Borrecho G, Matos APAd, Cabral JMS, Linhardt RJ, Ferreira FC. Effects of glycosaminoglycan supplementation in the chondrogenic differentiation of bone marrow- and synovial- derived mesenchymal stem/stromal cells on 3D-extruded poly (ε-caprolactone) scaffolds International Journal of Polymeric Materials. 1-16. DOI: 10.1080/00914037.2019.1706511  0.676
2020 Yang C, Gao L, Shao M, Cai C, Wang L, Chen Y, Li J, Fan F, Han Y, Liu M, Linhardt RJ, Yu G. End-functionalised glycopolymers as glycosaminoglycan mimetics inhibit HeLa cell proliferation Polymer Chemistry. 11: 4714-4722. DOI: 10.1039/D0Py00384K  0.654
2020 Feng K, Wei Y, Hu T, Linhardt RJ, Zong M, Wu H. Colon-targeted delivery systems for nutraceuticals: A review of current vehicles, evaluation methods and future prospects Trends in Food Science & Technology. 102: 203-222. DOI: 10.1016/J.Tifs.2020.05.019  0.374
2020 Cheng L, Zhang H, Liang H, Sun X, Shen X, Wang J, Wang W, Yuan Q, Ri H, Kim T, Kang M, Linhardt RJ. Enzymatic Bioconversion of Cycloastragenol-6-O-β-D-glucoside into Cycloastragenol by a Novel Recombinant β-Glucosidase from Phycicoccus sp. Soil748 Process Biochemistry. 90: 81-88. DOI: 10.1016/J.Procbio.2019.11.006  0.603
2020 Wang R, Zhao T, Zhuo J, Zhan C, Zhang F, Linhardt RJ, Bai Z, Yang Y. MAPK/HOG signaling pathway induced stress‐responsive damage repair is a mechanism for Pichia pastoris to survive from hyperosmotic stress Journal of Chemical Technology & Biotechnology. DOI: 10.1002/Jctb.6553  0.438
2020 Zhao J, Zhu Y, Song X, Xiao Y, Su G, Liu X, Wang Z, Xu Y, Liu J, Eliezer D, Ramlall TF, Lippens G, Gibson J, Zhang F, Linhardt RJ, et al. Frontispiz: 3‐ O ‐Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake Angewandte Chemie. 132. DOI: 10.1002/Ange.202080561  0.658
2020 Dimitrievska S, Wang J, Lin T, Weyers A, Bai H, Qin L, Li G, Cai C, Kypson A, Kristofik N, Gard A, Sundaram S, Yamamoto K, Wu W, Zhao L, ... ... Linhardt RJ, et al. Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts Advanced Functional Materials. 30: 1908963. DOI: 10.1002/Adfm.201908963  0.76
2019 Chen H, Zhang H, Tian J, Shi J, Linhardt RJ, Ye TDX, Chen S. Recovery of High Value-Added Nutrients from Fruit and Vegetable Industrial Wastewater. Comprehensive Reviews in Food Science and Food Safety. 18: 1388-1402. PMID 33336910 DOI: 10.1111/1541-4337.12477  0.423
2019 Garrudo FFF, Udangawa RN, Hoffman PR, Sordini L, Chapman CA, Mikael PE, Ferreira FA, Silva JC, Rodrigues CAV, Cabral JMS, Morgado JMF, Ferreira FC, Linhardt RJ. POLYBENZIMIDAZOLE NANOFIBERS FOR NEURAL STEM CELL CULTURE. Materials Today. Chemistry. 14. PMID 32864530 DOI: 10.1016/J.Mtchem.2019.08.004  0.778
2019 Stickney M, Sanderson P, Leach FE, Zhang F, Linhardt RJ, Amster IJ. Online Capillary Zone Electrophoresis Negative Electron Transfer Dissociation Tandem Mass Spectrometry of Glycosaminoglycan Mixtures. International Journal of Mass Spectrometry. 445. PMID 32641905 DOI: 10.1016/J.Ijms.2019.116209  0.53
2019 Londhe AD, Bergeron A, Curley SM, Zhang F, Rivera KD, Kannan A, Coulis G, Rizvi SHM, Kim SJ, Pappin DJ, Tonks NK, Linhardt RJ, Boivin B. Regulation of PTP1B activation through disruption of redox-complex formation. Nature Chemical Biology. PMID 31873221 DOI: 10.1038/S41589-019-0433-0  0.491
2019 Feng K, Huang RM, Wu RQ, Wei YS, Zong MH, Linhardt RJ, Wu H. A novel route for double-layered encapsulation of probiotics with improved viability under adverse conditions. Food Chemistry. 310: 125977. PMID 31837527 DOI: 10.1016/J.Foodchem.2019.125977  0.373
2019 Zhang F, Zhao J, Liu X, Linhardt RJ. Interactions between Sclerostin and Glycosaminoglycans. Glycoconjugate Journal. PMID 31828567 DOI: 10.1007/S10719-019-09900-3  0.682
2019 Mao G, Li S, Orfila C, Shen X, Zhou S, Linhardt RJ, Ye X, Chen S. Depolymerized RG-I-enriched pectin from citrus segment membranes modulates gut microbiota, increases SCFA production, and promotes the growth of Bifidobacterium spp., Lactobacillus spp. and Faecalibaculum spp. Food & Function. PMID 31778135 DOI: 10.1039/C9Fo01534E  0.533
2019 Kwon PS, Ren S, Kwon SJ, Kizer ME, Kuo L, Xie M, Zhu D, Zhou F, Zhang F, Kim D, Fraser K, Kramer LD, Seeman NC, Dordick JS, Linhardt RJ, et al. Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition. Nature Chemistry. PMID 31767992 DOI: 10.1038/S41557-019-0369-8  0.777
2019 Zhang B, Li Y, Zhang F, Linhardt RJ, Zeng G, Zhang A. Extraction, structure and bioactivities of the polysaccharides from Pleurotus eryngii: A Review. International Journal of Biological Macromolecules. PMID 31759001 DOI: 10.1016/J.Ijbiomac.2019.10.144  0.745
2019 Bista S, Singh P, Bernard Q, Yang X, Hart T, Lin YP, Kitsou C, Singh Rana V, Zhang F, Linhardt RJ, Zhnag K, Akins DR, Hritzo L, Kim Y, Grab DJ, et al. A novel laminin-binding protein mediates microbial-endothelial cell interactions and facilitates dissemination of Lyme disease pathogens. The Journal of Infectious Diseases. PMID 31758693 DOI: 10.1093/Infdis/Jiz626  0.489
2019 Uhl FE, Zhang F, Pouliot RA, Uriarte JJ, Enes SR, Han X, Ouyang Y, Xia K, Westergren-Thorsson G, Malmström A, Hallgren O, Linhardt RJ, Weiss DJ. Functional Role of Glycosaminoglycans in Decellularized Lung Extracellular Matrix. Acta Biomaterialia. PMID 31751810 DOI: 10.1016/J.Actbio.2019.11.029  0.616
2019 Zhang X, Lin L, Huang H, Linhardt RJ. Chemoenzymatic Synthesis of Glycosaminoglycans. Accounts of Chemical Research. PMID 31714740 DOI: 10.1021/Acs.Accounts.9B00420  0.646
2019 Zhang F, Datta P, Dordick JS, Linhardt RJ. Evaluating heparin products for heparin-induced thrombocytopenia using surface plasmon resonance. Journal of Pharmaceutical Sciences. PMID 31705871 DOI: 10.1016/J.Xphs.2019.10.040  0.645
2019 Zhao J, Zhu Y, Song X, Xiao Y, Su G, Liu X, Wang Z, Xu Y, Liu J, Eliezer D, Ramlall TF, Lippens G, Gibson J, Zhang F, Linhardt RJ, et al. Rare 3-O-sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake. Angewandte Chemie (International Ed. in English). PMID 31692167 DOI: 10.1002/Anie.201913029  0.678
2019 Ha X, Sanderson P, Nesheiwat S, Lin L, Yu Y, Zhang F, Amster IJ, Linhardt RJ. Structural Analysis of Urinary Glycosaminoglycans from Healthy Human Subjects. Glycobiology. PMID 31616929 DOI: 10.1093/Glycob/Cwz088  0.752
2019 Wu D, Zheng J, Mao G, Hu W, Ye X, Linhardt RJ, Chen S. Rethinking the impact of RG-I mainly from fruits and vegetables on dietary health. Critical Reviews in Food Science and Nutrition. 1-23. PMID 31607142 DOI: 10.1080/10408398.2019.1672037  0.51
2019 Zhu TW, Zhang X, Zong MH, Linhardt RJ, Wu H, Li B. Storage stability studies on interesterified blend-based fast-frozen special fats for oxidative stability, crystallization characteristics and physical properties. Food Chemistry. 306: 125563. PMID 31606626 DOI: 10.1016/J.Foodchem.2019.125563  0.427
2019 Silva JC, Moura CS, Borrecho G, de Matos APA, da Silva CL, Cabral JMS, Bártolo PJ, Linhardt RJ, Ferreira FC. Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly (ε-Caprolactone) Scaffolds. Biotechnology Journal. e1900078. PMID 31560160 DOI: 10.1002/Biot.201900078  0.693
2019 Pawar NJ, Wang L, Higo T, Bhattacharya C, Kancharla PK, Zhang F, Baryal K, Huo CX, Jian Liu J, Linhardt RJ, Xuefei Huang X, Hsieh-Wilson LC. Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly. Angewandte Chemie (International Ed. in English). PMID 31553820 DOI: 10.1002/Anie.201908805  0.674
2019 Zhang F, Zheng L, Cheng S, Peng Y, Fu L, Zhang X, Linhardt RJ. Comparison of the Interactions of Different Growth Factors and Glycosaminoglycans. Molecules (Basel, Switzerland). 24. PMID 31527407 DOI: 10.3390/Molecules24183360  0.78
2019 Lin L, Yu Y, Zhang F, Zhang X, Linhardt RJ. High-throughput method for in process monitoring of 3-O-sulfotransferase catalyzed sulfonation in bioengineered heparin synthesis. Analytical Biochemistry. 113419. PMID 31518551 DOI: 10.1016/J.Ab.2019.113419  0.778
2019 Oshima K, Han X, Ouyang Y, El Masri R, Yang Y, Haeger SM, McMurtry SA, Lane TC, Davizon-Castillo P, Zhang F, Yue X, Vivès RR, Linhardt RJ, Schmidt EP. Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31461325 DOI: 10.1152/Ajplung.00175.2019  0.483
2019 Williams A, Gedeon KS, Vaidyanathan D, Yu Y, Collins CH, Dordick JS, Linhardt RJ, Koffas MAG. Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2. Microbial Cell Factories. 18: 132. PMID 31405374 DOI: 10.1186/S12934-019-1187-9  0.619
2019 Yan L, Li L, Li J, Yu Y, Liu X, Ye X, Linhardt RJ, Chen S. Bottom-up analysis using liquid chromatography-Fourier transform mass spectrometry to characterize fucosylated chondroitin sulfates from sea cucumbers. Glycobiology. PMID 31360991 DOI: 10.1093/Glycob/Cwz057  0.769
2019 Hippensteel JA, Uchimido R, Tyler PD, Burke RC, Han X, Zhang F, McMurtry SA, Colbert JF, Lindsell CJ, Angus DC, Kellum JA, Yealy DM, Linhardt RJ, Shapiro NI, Schmidt EP. Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation. Critical Care (London, England). 23: 259. PMID 31337421 DOI: 10.1186/S13054-019-2534-2  0.46
2019 Yan L, Wang D, Zhu M, Yu Y, Zhang F, Ye X, Linhardt RJ, Chen S. Highly purified fucosylated chondroitin sulfate oligomers with selective intrinsic factor Xase complex inhibition. Carbohydrate Polymers. 222: 115025. PMID 31320079 DOI: 10.1016/J.Carbpol.2019.115025  0.757
2019 Wu N, Silva LM, Liu Y, Zhang Y, Gao C, Zhang F, Fu L, Peng Y, Linhardt R, Kawasaki T, Mulloy B, Chai W, Feizi T. Glycan Markers of Human Stem Cells Assigned with Beam Search Arrays. Molecular & Cellular Proteomics : McP. PMID 31308253 DOI: 10.1074/Mcp.Ra119.001309  0.778
2019 Lin L, Yu Y, Zhang F, Xia K, Zhang X, Linhardt RJ. Bottom-up and top-down profiling of pentosan polysulfate. The Analyst. PMID 31287456 DOI: 10.1039/C9An01006H  0.803
2019 Zhu TW, Zhang X, Zong MH, Linhardt RJ, Li B, Wu H. Interesterified blend-based and physical blend-based special fats: Storage stability under fluctuating temperatures. Journal of the Science of Food and Agriculture. PMID 31250449 DOI: 10.1002/Jsfa.9894  0.419
2019 Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG. Increased 3'-phosphoadenosine-5'-phosphosulfate levels in engineered Escherichia coli cell lysate facilitates in vitro synthesis of Chondroitin Sulfate A. Biotechnology Journal. e1800436. PMID 31180182 DOI: 10.1002/Biot.201800436  0.498
2019 Yu Y, Williams A, Zhang X, Fu L, Xia K, Xu Y, Zhang F, Liu J, Koffas M, Linhardt RJ. Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei. Glycobiology. PMID 31143933 DOI: 10.1093/Glycob/Cwz039  0.801
2019 Despres C, Di J, Cantrelle FX, Li Z, Huvent I, Chambraud B, Zhao J, Chen J, Chen S, Lippens G, Zhang F, Linhardt R, Wang C, Klärner FG, Schrader T, et al. Major differences between the self-assembly and seeding behavior of heparin-induced- and in-vitro-phosphorylated tau and their modulation by potential inhibitors. Acs Chemical Biology. PMID 31046227 DOI: 10.1021/Acschembio.9B00325  0.636
2019 Ouyang Y, Zhu M, Wang X, Yi L, Fareed J, Linhardt RJ, Zhang Z. Systematic analysis of enoxaparins from different sources with online one- and two-dimensional chromatography. The Analyst. PMID 31016304 DOI: 10.1039/C9An00399A  0.621
2019 Zhang X, Han X, Xia K, Xu Y, Yang Y, Oshima K, Haeger SM, Perez MJ, McMurtry SA, Hippensteel JA, Ford JA, Herson PS, Liu J, Schmidt EP, Linhardt RJ. Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31010931 DOI: 10.1073/Pnas.1902227116  0.596
2019 Chen J, Yu Y, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Jin C, Jin Y, Yao Y, Xia K, Zhang F, Chen S, Ye X, Linhardt RJ. Comparison of Low-Molecular-Weight Heparins Prepared From Ovine Heparins With Enoxaparin. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 25: 1076029619840701. PMID 30987427 DOI: 10.1177/1076029619840701  0.781
2019 Kizer ME, Linhardt RJ, Chandrasekaran AR, Wang X. A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures. Small (Weinheim An Der Bergstrasse, Germany). e1805386. PMID 30985074 DOI: 10.1002/Smll.201805386  0.764
2019 Udangawa RN, Mikael PE, Mancinelli C, Chapman C, Willard C, Simmons TJ, Linhardt RJ. Novel Cellulose - Halloysite Hemostatic Nanocomposite Fibers with a Dramatic Reduction in Human Plasma Coagulation Time. Acs Applied Materials & Interfaces. PMID 30977359 DOI: 10.1021/Acsami.9B04615  0.775
2019 Xu Y, Wu YJ, Sun PL, Zhang FM, Linhardt RJ, Zhang AQ. Chemically modified polysaccharides: Synthesis, characterization, structure activity relationships of action. International Journal of Biological Macromolecules. PMID 30965077 DOI: 10.1016/J.Ijbiomac.2019.03.213  0.649
2019 Kim SY, Kundu J, Williams A, Yandulskaya AS, Monaghan JR, Carrier RL, Linhardt RJ. Glycosaminoglycans compositional analysis of Urodele axolotl (Ambystoma mexicanum) and Porcine Retina. Glycoconjugate Journal. PMID 30963354 DOI: 10.1007/S10719-019-09863-5  0.394
2019 Shen X, Liu Z, Li J, Wu D, Zhu M, Yan L, Mao G, Ye X, Linhardt RJ, Chen S. Development of low molecular weight heparin by HO/ascorbic acid with ultrasonic power and its anti-metastasis property. International Journal of Biological Macromolecules. PMID 30954594 DOI: 10.1016/J.Ijbiomac.2019.04.019  0.544
2019 Carvalho MS, Silva JC, Udangawa RN, Cabral JMS, Ferreira FC, da Silva CL, Linhardt RJ, Vashishth D. Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering. Materials Science & Engineering. C, Materials For Biological Applications. 99: 479-490. PMID 30889723 DOI: 10.1016/J.Msec.2019.01.127  0.69
2019 Cress BF, Bhaskar U, Vaidyanathan D, Williams A, Cai C, Liu X, Fu L, M-Chari V, Zhang F, Mousa SA, Dordick JS, Koffas MAG, Linhardt RJ. Heavy heparin: A stable isotope-enriched, chemoenzymatically-synthesized, poly-component drug. Angewandte Chemie (International Ed. in English). PMID 30870573 DOI: 10.1002/Anie.201900768  0.799
2019 Wen P, Hu TG, Wen Y, Linhardt RJ, Zong MH, Zou YX, Wu H. Targeted delivery of phycocyanin for the prevention of colon cancer using electrospun fibers. Food & Function. PMID 30806395 DOI: 10.1039/C8Fo02447B  0.375
2019 Xia K, Bao H, Zhang F, Linhardt RJ, Liang X. Characterization and comparative analysis of toxin-antitoxin systems in Acetobacter pasteurianus. Journal of Industrial Microbiology & Biotechnology. PMID 30805740 DOI: 10.1007/S10295-019-02144-Y  0.73
2019 Cheng S, Wantuch PL, Kizer ME, Middleton DR, Wang R, DiBello M, Li M, Wang X, Li X, Ramachandiran V, Avci FY, Zhang F, Zhang X, Linhardt RJ. Glycoconjugate synthesis using chemoselective ligation. Organic & Biomolecular Chemistry. PMID 30778481 DOI: 10.1039/C9Ob00270G  0.78
2019 Li J, Li S, Wu L, Yang H, Wei C, Ding T, Linhardt RJ, Zheng X, Ye X, Chen S. Ultrasound-assisted fast preparation of low molecular weight fucosylated chondroitin sulfate with antitumor activity. Carbohydrate Polymers. 209: 82-91. PMID 30732828 DOI: 10.1016/J.Carbpol.2018.12.061  0.568
2019 Hippensteel JA, Anderson BJ, Orfila JE, McMurtry SA, Dietz RM, Su G, Ford JA, Oshima K, Yang Y, Zhang F, Han X, Yu Y, Liu J, Linhardt RJ, Meyer NJ, et al. Circulating heparan sulfate fragments mediate septic cognitive dysfunction. The Journal of Clinical Investigation. PMID 30720464 DOI: 10.1172/Jci124485  0.696
2019 Kim SY, Koetzner CA, Payne AF, Nierode GJ, Yu Y, Wang RF, Barr E, Dordick JS, Kramer L, Zhang F, Linhardt RJ. Glycosaminoglycan Compositional Analysis of Relevant Tissues in ZIKV Pathogenesis and in vitro Evaluation of Heparin as Antiviral Against ZIKV Infection. Biochemistry. PMID 30698412 DOI: 10.1021/Acs.Biochem.8B01267  0.721
2019 Silva JC, Carvalho MS, Han X, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ. Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices. Glycoconjugate Journal. PMID 30637588 DOI: 10.1007/S10719-019-09858-2  0.796
2019 Ouyang Y, Yu Y, Zhang F, Chen J, Han X, Xia K, Yao Y, Zhang Z, Linhardt RJ. Non-Anticoagulant Low Molecular Weight Heparins for Pharmaceutical Applications. Journal of Medicinal Chemistry. PMID 30608147 DOI: 10.1021/Acs.Jmedchem.8B01551  0.807
2019 Wei C, Zhang Y, He L, Cheng J, Li J, Tao W, Mao G, Zhang H, Linhardt RJ, Ye X, Chen S. Structural characterization and anti-proliferative activities of partially degraded polysaccharides from peach gum. Carbohydrate Polymers. 203: 193-202. PMID 30318204 DOI: 10.1016/J.Carbpol.2018.09.029  0.538
2019 Chen H, Zhang H, Tian J, Shi J, Linhardt RJ, Ye TDX, Chen S. Recovery of High Value‐Added Nutrients from Fruit and Vegetable Industrial Wastewater Comprehensive Reviews in Food Science and Food Safety. 18: 1388-1402. DOI: 10.1111/1541-4337.12477  0.468
2019 Wang F, Huang D, Ma Y, Zhang F, Linhardt RJ. Preparation of salidroside with n-butyl β-D-glucoside as the glycone donor via a two-step enzymatic synthesis catalyzed by immobilized β-glucosidase from bitter almonds Biocatalysis and Biotransformation. 37: 246-260. DOI: 10.1080/10242422.2018.1549236  0.472
2019 Shi C, Zhang S, Wang W, Linhardt RJ, Ragauskas AJ. Preparation of Highly Reactive Lignin by Ozone Oxidation: Application as Surfactants with Antioxidant and Anti-UV Properties Acs Sustainable Chemistry & Engineering. 8: 22-28. DOI: 10.1021/Acssuschemeng.9B05498  0.602
2019 Mao G, Wu D, Wei C, Tao W, Ye X, Linhardt RJ, Orfila C, Chen S. Reconsidering conventional and innovative methods for pectin extraction from fruit and vegetable waste: Targeting rhamnogalacturonan I Trends in Food Science & Technology. 94: 65-78. DOI: 10.1016/J.Tifs.2019.11.001  0.516
2019 Zhang X, Dickinson DM, Lin L, Suflita M, Baytas S, Linhardt RJ. Chemoenzymatic synthesis of heparan sulfate tetrasaccharide from a N-acetyl-α-d-glucosamine-O-methylglycoside acceptor Tetrahedron Letters. 60: 911-915. DOI: 10.1016/J.Tetlet.2019.02.036  0.783
2019 Garrudo F, Udangawa R, Hoffman P, Sordini L, Chapman C, Mikael P, Ferreira F, Silva J, Rodrigues C, Cabral J, Morgado J, Ferreira F, Linhardt R. Polybenzimidazole nanofibers for neural stem cell culture Materials Today Chemistry. 14: 100185. DOI: 10.1016/j.mtchem.2019.08.004  0.748
2019 Xing C, Qin C, Li X, Zhang F, Linhardt RJ, Sun P, Zhang A. Chemical composition and biological activities of essential oil isolated by HS-SPME and UAHD from fruits of bergamot Lwt. 104: 38-44. DOI: 10.1016/J.Lwt.2019.01.020  0.784
2019 Li S, Li J, Mao G, Yan L, Hu Y, Ye X, Tian D, Linhardt RJ, Chen S. Effect of the sulfation pattern of sea cucumber-derived fucoidan oligosaccharides on modulating metabolic syndromes and gut microbiota dysbiosis caused by HFD in mice Journal of Functional Foods. 55: 193-210. DOI: 10.1016/J.Jff.2019.02.001  0.516
2019 Xiao Y, Zhao J, Wang C, Zhang F, Linhardt R, Su G, Liu J, Zhu Y, Wang L. P4-521: 3-O-Sulfo Group Is A Key Determinant In Tau-Glycan Interaction Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.068  0.547
2019 Bitan G, Despres C, Di J, Cantrelle F, Li Z, Huvent I, Chambraud B, Zhao J, Chen J, Chen S, Lippens G, Zhang F, Linhardt R, Wang C, Klärner F, et al. F2-06-01: MAJOR DIFFERENCES BETWEEN THE SELF-ASSEMBLY, SEEDING BEHAVIOR, AND INTERACTION WITH MODULATORS OF HEPARIN-INDUCED VERSUS IN-VITRO PHOSPHORYLATED TAU Alzheimer's & Dementia. 15: P524-P525. DOI: 10.1016/J.Jalz.2019.06.4436  0.498
2019 Li J, Li S, Zheng Y, Zhang H, Chen J, Yan L, Ding T, Linhardt RJ, Orfila C, Liu D, Ye X, Chen S. Fast preparation of rhamnogalacturonan I enriched low molecular weight pectic polysaccharide by ultrasonically accelerated metal-free Fenton reaction Food Hydrocolloids. 95: 551-561. DOI: 10.1016/J.Foodhyd.2018.05.025  0.55
2019 Wei C, Zhang Y, Zhang H, Li J, Tao W, Linhardt RJ, Chen S, Ye X. Physicochemical properties and conformations of water-soluble peach gums via different preparation methods Food Hydrocolloids. 95: 571-579. DOI: 10.1016/J.Foodhyd.2018.03.049  0.52
2019 Garrudo FF, Chapman CA, Hoffman PR, Udangawa RW, Silva JC, Mikael PE, Rodrigues CA, Cabral JM, Morgado JM, Ferreira FC, Linhardt RJ. Polyaniline-polycaprolactone blended nanofibers for neural cell culture European Polymer Journal. 117: 28-37. DOI: 10.1016/J.Eurpolymj.2019.04.048  0.767
2019 Zhang Z, Ruan Z, Liu J, Liu C, Zhang F, Linhardt RJ, Li L. Complete degradation of bisphenol A and nonylphenol by a composite of biogenic manganese oxides and Escherichia coli cells with surface-displayed multicopper oxidase CotA Chemical Engineering Journal. 362: 897-908. DOI: 10.1016/J.Cej.2019.01.062  0.509
2019 Sarnaik A, Abernathy MH, Han X, Ouyang Y, Xia K, Chen Y, Cress B, Zhang F, Lali A, Pandit R, Linhardt RJ, Tang YJ, Koffas MA. Metabolic engineering of cyanobacteria for photoautotrophic production of heparosan, a pharmaceutical precursor of heparin Algal Research. 37: 57-63. DOI: 10.1016/J.Algal.2018.11.010  0.788
2019 Mikael PE, Udangawa R, Sorci M, Cress B, Shtein Z, Belfort G, Shoseyov O, Dordick JS, Linhardt RJ. Production and Characterization of Recombinant Collagen-Binding Resilin Nanocomposite for Regenerative Medicine Applications Regenerative Engineering and Translational Medicine. 5: 362-372. DOI: 10.1007/s40883-019-00092-8  0.687
2019 Wang W, Wang S, Pan Y, Ouyang X, Linhardt RJ. Fermented Cassava Residue Lignin Prepared by Sequential Acid Steam-Explosion and Hot-Alkaline Treatment and Its Antioxidant Properties Waste and Biomass Valorization. 1-10. DOI: 10.1007/S12649-019-00862-Z  0.629
2019 Kizer ME, Linhardt RJ, Chandrasekaran AR, Wang X. DNA Nanostructures: A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures (Small 26/2019) Small. 15: 1970141. DOI: 10.1002/Smll.201970141  0.75
2019 Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG. Outside Back Cover: Biotechnology Journal 9/2019 Biotechnology Journal. 14: 1970095. DOI: 10.1002/Biot.201970095  0.434
2018 Zheng L, Zhu X, Yang K, Zhu M, Farooqi AA, Kang D, Sun M, Xu Y, Lin X, Feng Y, Liang F, Zhang F, Linhardt RJ. PBN11-8, a Cytotoxic Polypeptide Purified from Marine , Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. Polymers. 10. PMID 30960968 DOI: 10.3390/Polym10091043  0.774
2018 He Z, Han Z, Kizer M, Linhardt RJ, Wang X, Sinyukov AM, Wang J, Deckert V, Sokolov AV, Hu J, Scully MO. Tip-enhanced Raman imaging of single-stranded DNA with single base resolution. Journal of the American Chemical Society. PMID 30586988 DOI: 10.1021/Jacs.8B11506  0.762
2018 Mikael P, Willard C, Koyee A, Barlao CG, Liu X, Han X, Ouyang Y, Xia K, Linhardt RJ, Dordick JS. Remodeling of Glycosaminoglycans During Differentiation of Adult Human Bone Mesenchymal Stromal Cells toward Hepatocytes. Stem Cells and Development. PMID 30572803 DOI: 10.1089/Scd.2018.0197  0.779
2018 Yu Y, Zhang F, Colón W, Linhardt RJ, Xia K. Glycosaminoglycans in human cerebrospinal fluid determined by LC-MS/MS MRM. Analytical Biochemistry. PMID 30571946 DOI: 10.1016/J.Ab.2018.12.013  0.779
2018 Zhi Z, Li J, Chen J, Li S, Cheng H, Liu D, Ye X, Linhardt RJ, Chen S. Preparation of low molecular weight heparin using an ultrasound-assisted Fenton-system. Ultrasonics Sonochemistry. PMID 30559077 DOI: 10.1016/J.Ultsonch.2018.11.016  0.571
2018 Ouyang Y, Han X, Xia Q, Chen J, Velagapudi S, Xia K, Zhang Z, Linhardt RJ. Negative-Ion Mode Capillary Isoelectric Focusing-Mass Spectrometry for Charge-Based Separation of Acidic Oligosaccharides. Analytical Chemistry. PMID 30516363 DOI: 10.1021/Acs.Analchem.8B03500  0.67
2018 Wang F, Zhu J, Yan T, Pei X, Zhang F, Linhardt RJ. Amphiphilic bromelain-synthesized oligo-phenylalanine grafted with methoxypolyethylene glycol possessing stabilizing thermo-responsive emulsion properties. Journal of Colloid and Interface Science. 538: 1-14. PMID 30481653 DOI: 10.1016/J.Jcis.2018.11.082  0.503
2018 Wu F, Dong K, Zhu M, Zhang Q, Xie B, Li D, Gan H, Linhardt RJ, Zhang Z. Development of a method to analyze the complexes of enoxaparin and platelet factor 4 with size-exclusion chromatography. Journal of Pharmaceutical and Biomedical Analysis. 164: 668-671. PMID 30472585 DOI: 10.1016/J.Jpba.2018.11.018  0.588
2018 Li J, Li S, Liu S, Wei C, Yan L, Ding T, Linhardt RJ, Liu D, Ye X, Chen S. Pectic oligosaccharides hydrolyzed from citrus canning processing water by Fenton reaction and their antiproliferation potentials. International Journal of Biological Macromolecules. PMID 30465847 DOI: 10.1016/J.Ijbiomac.2018.11.166  0.532
2018 Li S, Li J, Mao G, Wu T, Lin D, Hu Y, Ye X, Tian D, Chai W, Linhardt RJ, Chen S. Fucosylated chondroitin sulfate from Isostichopus badionotus alleviates metabolic syndromes and gut microbiota dysbiosis induced by high-fat and high-fructose diet. International Journal of Biological Macromolecules. PMID 30465844 DOI: 10.1016/J.Ijbiomac.2018.11.167  0.485
2018 Sladden TM, Yerkovich S, Grant M, Zhang F, Liu X, Trotter M, Hopkins P, Linhardt RJ, Chambers DC. ENDOTHELIAL GLYCOCALYX SHEDDING PREDICTS DONOR ORGAN ACCEPTABILITY AND IS ASSOCIATED WITH PRIMARY GRAFT DYSFUNCTION IN LUNG TRANSPLANT RECIPIENTS. Transplantation. PMID 30444804 DOI: 10.1097/Tp.0000000000002539  0.601
2018 Ouyang Y, Han X, Yu Y, Chen J, Fu L, Zhang F, Linhardt RJ, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Zhang Z, Xia K. Chemometric analysis of porcine, bovine and ovine heparins. Journal of Pharmaceutical and Biomedical Analysis. 164: 345-352. PMID 30428408 DOI: 10.1016/J.Jpba.2018.10.052  0.796
2018 Kizer M, Li P, Cress BF, Lin L, Jing TT, Zhang X, Xia K, Linhardt RJ, Wang X. RNA Aptamers with Specificity for Heparosan and Chondroitin Glycosaminoglycans. Acs Omega. 3: 13667-13675. PMID 30411046 DOI: 10.1021/acsomega.8b01853  0.775
2018 Yamaguchi K, Asakura K, Imamura M, Kawai G, Sakamoto T, Furihata T, Linhardt RJ, Igarashi K, Toida T, Higashi K. Polyamines stimulate the CHSY1 synthesis through the unfolding of the RNA G-quadruplex at the 5'-untraslated region. The Biochemical Journal. PMID 30401686 DOI: 10.1042/Bcj20180672  0.557
2018 Qiu H, Shi S, Yue J, Xin M, Nairn AV, Lin L, Liu X, Li G, Archer-Hartmann SA, Dela Rosa M, Galizzi M, Wang S, Zhang F, Azadi P, van Kuppevelt TH, ... ... Linhardt RJ, et al. A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships. Nature Methods. PMID 30377379 DOI: 10.1038/S41592-018-0189-6  0.787
2018 Wu YJ, Wei ZX, Zhang FM, Linhardt RJ, Sun PL, Zhang AQ. Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review. International Journal of Biological Macromolecules. PMID 30342120 DOI: 10.1016/J.Ijbiomac.2018.10.117  0.628
2018 Gupta M, Zha J, Zhang X, Jung GY, Linhardt RJ, Koffas MAG. Production of Deuterated Cyanidin 3--Glucoside from Recombinant . Acs Omega. 3: 11643-11648. PMID 30320269 DOI: 10.1021/acsomega.8b01134  0.335
2018 Slaker ML, Jorgensen ET, Hegarty DM, Liu X, Kong Y, Zhang F, Linhardt RJ, Brown TE, Aicher SA, Sorg BA. Cocaine Exposure Modulates Perineuronal Nets and Synaptic Excitability of Fast-Spiking Interneurons in the Medial Prefrontal Cortex. Eneuro. 5. PMID 30294670 DOI: 10.1523/ENEURO.0221-18.2018  0.649
2018 Wang W, Li Y, Wang Y, Shi C, Li C, Li Q, Linhardt RJ. Bacteriophage T7 transcription system: an enabling tool in synthetic biology. Biotechnology Advances. PMID 30290194 DOI: 10.1016/J.Biotechadv.2018.10.001  0.591
2018 Zhao J, Kong Y, Zhang F, Linhardt RJ. Impact of Temperature on Heparin and Protein Interactions. Biochemistry & Physiology. 7. PMID 30271699 DOI: 10.4172/2168-9652.1000241  0.62
2018 Li S, Li J, Mao G, Wu T, Hu Y, Ye X, Tian D, Linhardt RJ, Chen S. A fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated structure alleviates gut microbiota dysbiosis and metabolic syndromes in HFD-fed mice. Food & Function. PMID 30264830 DOI: 10.1039/C8Fo01174E  0.489
2018 Feng K, Zhai M, Zhang Y, Linhardt RJ, Zong M, Li L, Wu H. Improved viability and thermal stability of the probiotics encapsulated in a novel electrospun fiber mat. Journal of Agricultural and Food Chemistry. PMID 30260640 DOI: 10.1021/Acs.Jafc.8B02644  0.38
2018 Xiao Y, Li M, Larocque R, Zhang F, Malhotra A, Chen J, Linhardt RJ, Konermann L, Xu D. Dimerization Interface of Osteoprotegerin Revealed by Hydrogen-deuterium Exchange Mass Spectrometry. The Journal of Biological Chemistry. PMID 30254073 DOI: 10.1074/Jbc.Ra118.004489  0.517
2018 Li S, Li J, Mao G, Hu Y, Ye X, Tian D, Linhardt RJ, Chen S. Fucosylated chondroitin sulfate oligosaccharides from Isostichopus badionotus regulates lipid disorder in C57BL/6 mice fed a high-fat diet. Carbohydrate Polymers. 201: 634-642. PMID 30241863 DOI: 10.1016/J.Carbpol.2018.08.020  0.49
2018 Wang Y, Shen J, Yang X, Jin Y, Yang Z, Wang R, Zhang F, Linhardt RJ. Mechanism of enhanced oral absorption of Akebia saponin D by a self-nanoemulsifying drug delivery system loaded with phospholipid complex. Drug Development and Industrial Pharmacy. 1-19. PMID 30229685 DOI: 10.1080/03639045.2018.1526183  0.478
2018 Kim SY, Zhang F, Gong W, Chen K, Xia K, Liu F, Gross RA, Wang JM, Linhardt RJ, Cotten ML. Copper regulates the interactions of antimicrobial piscidin peptides from fish mast cells with formyl peptide receptors and heparin. The Journal of Biological Chemistry. PMID 30158246 DOI: 10.1074/Jbc.Ra118.001904  0.634
2018 Wang Y, Shen J, Yang X, Jin Y, Yang Z, Wang R, Zhang F, Linhardt RJ. Akebia saponin D reverses corticosterone hypersecretion in an Alzheimer's disease rat model. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 107: 219-225. PMID 30092401 DOI: 10.1016/J.Biopha.2018.07.149  0.452
2018 Siegel RA, Brown L, Edelman ER, Linhardt RJ. B'reshith. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 252-257. PMID 30078756 DOI: 10.1016/j.jconrel.2018.07.005  0.543
2018 Xie S, Guan Y, Zhu P, Li F, Yu M, Linhardt RJ, Chi L, Jin L. Preparation of low molecular weight heparins from bovine and ovine heparins using nitrous acid degradation. Carbohydrate Polymers. 197: 83-91. PMID 30007661 DOI: 10.1016/J.Carbpol.2018.05.070  0.801
2018 Ando T, Nagumo M, Ninomiya M, Tanaka K, Linhardt RJ, Koketsu M. Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells. Bioorganic & Medicinal Chemistry Letters. PMID 29914769 DOI: 10.1016/J.Bmcl.2018.06.018  0.505
2018 Jin W, Li S, Chen J, Liu B, Li J, Li X, Zhang F, Linhardt RJ, Zhong W. Increased soluble heterologous expression of a rat brain 3-O-sulfotransferase 1 - A key enzyme for heparin biosynthesis. Protein Expression and Purification. PMID 29894802 DOI: 10.1016/J.Pep.2018.06.007  0.682
2018 Yu Y, Linhardt RJ. Xylosyltransferase 1 and the GAG Attachment Site. Structure (London, England : 1993). 26: 797-799. PMID 29874596 DOI: 10.1016/J.Str.2018.05.011  0.608
2018 Hart T, Nguyen NTT, Nowak NA, Zhang F, Linhardt RJ, Diuk-Wasser M, Ram S, Kraiczy P, Lin YP. Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission. Plos Pathogens. 14: e1007106. PMID 29813137 DOI: 10.1371/Journal.Ppat.1007106  0.491
2018 Bhattacharyya S, Feferman L, Han X, Ouyang Y, Zhang F, Linhardt RJ, Tobacman JK. Decline in Arylsulfatase B Expression Increases EGFR Expression by Inhibiting the Protein Tyrosine Phosphatase SHP2 and Activating JNK in Prostate Cells. The Journal of Biological Chemistry. PMID 29794138 DOI: 10.1074/Jbc.Ra117.001244  0.492
2018 Peng X, Peng Y, Han B, Liu W, Zhang F, Linhardt RJ. IO4--stimulated crosslinking of catechol-conjugated hydroxyethyl chitosan as a tissue adhesive. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 29732734 DOI: 10.1002/Jbm.B.34150  0.75
2018 Zhang X, Xia K, Lin L, Zhang F, Yu Y, St Ange K, Han X, Edsinger E, Sohn JJ, Linhardt RJ. Structural and functional components of the skate sensory organ ampullae of Lorenzini. Acs Chemical Biology. PMID 29708722 DOI: 10.1021/Acschembio.8B00335  0.785
2018 Zheng L, Lin X, Yuan Z, Liu M, Cao S, Zhang F, Linhardt RJ. Recent Progress of Marine Polypeptides as Anticancer Agents Marine Polypeptides as Anticancer Agents. Recent Patents On Anti-Cancer Drug Discovery. PMID 29708076 DOI: 10.2174/1574892813666180430110033  0.766
2018 Li Q, Li G, Zhao X, Shan X, Cai C, Zhao J, Zhang F, Linhardt RJ, Yu G. Structural Characterization and Interaction with RCA of a Highly Sulfated Keratan Sulfate from Blue Shark (Prionace glauca) Cartilage. Marine Drugs. 16. PMID 29662015 DOI: 10.3390/Md16040128  0.807
2018 Zhang A, Deng J, Yu S, Zhang F, Linhardt RJ, Sun P. Purification and structural elucidation of a water-soluble polysaccharide from the fruiting bodies of the Grifola frondosa. International Journal of Biological Macromolecules. PMID 29660454 DOI: 10.1016/J.Ijbiomac.2018.04.061  0.784
2018 Haeger SM, Liu X, Han X, McNeil JB, Oshima K, McMurtry SA, Yang Y, Ouyang Y, Zhang F, Nozik-Grayck E, Zemans RL, Tuder RM, Bastarache JA, Linhardt RJ, Schmidt EP. Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and is Shed During Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 29584451 DOI: 10.1165/Rcmb.2017-0428Oc  0.617
2018 Zhang A, Deng J, Liu X, He P, He L, Zhang F, Linhardt RJ, Sun P. Structure and conformation of α-glucan extracted from Agaricus blazei Murill by high-speed shearing homogenization. International Journal of Biological Macromolecules. PMID 29501839 DOI: 10.1016/J.Ijbiomac.2018.02.151  0.784
2018 Sanderson P, Stickney M, Leach FE, Xia Q, Yu Y, Zhang F, Linhardt RJ, Amster IJ. Heparin/heparan sulfate analysis by covalently modified reverse polarity capillary zone electrophoresis-mass spectrometry. Journal of Chromatography. A. PMID 29501428 DOI: 10.1016/J.Chroma.2018.02.052  0.707
2018 Okamoto Y, Higashi K, Linhardt RJ, Toida T. Comprehensive analysis of glycosaminoglycans from the edible shellfish. Carbohydrate Polymers. 184: 269-276. PMID 29352919 DOI: 10.1016/J.Carbpol.2017.12.076  0.57
2018 Wang Z, Zhang T, Xie S, Liu X, Li H, Linhardt RJ, Chi L. Sequencing the oligosaccharide pool in the low molecular weight heparin dalteparin with offline HPLC and ESI-MS/MS. Carbohydrate Polymers. 183: 81-90. PMID 29352895 DOI: 10.1016/J.Carbpol.2017.11.039  0.726
2018 Chen Y, Zhao J, Yu Y, Liu X, Lin L, Zhang F, Linhardt RJ. Antithrombin III Binding Site Analysis of Low Molecular Weight Heparin Fractions. Journal of Pharmaceutical Sciences. PMID 29339133 DOI: 10.1016/J.Xphs.2018.01.008  0.805
2018 Shirke AN, White C, Englaender JA, Zwarycz AS, Butterfoss GL, Linhardt RJ, Gross RA. Stabilizing leaf and branch compost cutinase (LCC) with glycosylation: Mechanism and effect on PET hydrolysis. Biochemistry. PMID 29328676 DOI: 10.1021/Acs.Biochem.7B01189  0.776
2018 Peng Y, Yu Y, Lin L, Liu X, Zhang X, Wang P, Hoffman P, Kim SY, Zhang F, Linhardt RJ. Glycosaminoglycans from bovine eye vitreous humour and interaction with collagen type II. Glycoconjugate Journal. PMID 29305777 DOI: 10.1007/S10719-017-9808-1  0.784
2018 Li Q, Cai C, Chang Y, Zhang F, Linhardt RJ, Xue C, Li G, Yu G. A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulation. Carbohydrate Polymers. 181: 1160-1168. PMID 29253945 DOI: 10.1016/J.Carbpol.2017.10.100  0.793
2018 Solakyildirim K, Li L, Linhardt RJ. Mass Spectrometry in the Determination of Glycosylation Site and N-Glycan Structures of Human Placental Alkaline Phosphatase Mass Spectrometry Letters. 9: 67-72. DOI: 10.5478/Msl.2018.9.3.67  0.729
2018 Li L, Huang L, Linhardt RJ, Koratkar N, Simmons T. Repurposing paper by-product lignosulfonate as a sulfur donor/acceptor for high performance lithium–sulfur batteries Sustainable Energy & Fuels. 2: 422-429. DOI: 10.1039/C7Se00394C  0.76
2018 Yan L, Ye X, Linhardt RJ, Chen J, Yu D, Huang R, Liu D, Chen S. Full recovery of value-added compounds from citrus canning processing water Journal of Cleaner Production. 176: 959-965. DOI: 10.1016/J.Jclepro.2017.12.018  0.519
2018 Zhang H, Chen J, Li J, Yan L, Li S, Ye X, Liu D, Ding T, Linhardt RJ, Orfila C, Chen S. Extraction and characterization of RG-I enriched pectic polysaccharides from mandarin citrus peel Food Hydrocolloids. 79: 579-586. DOI: 10.1016/J.Foodhyd.2017.12.002  0.552
2018 Li L, Hou L, Cheng J, Simmons T, Zhang F, Zhang LT, Linhardt RJ, Koratkar N. A flexible carbon/sulfur-cellulose core-shell structure for advanced lithium–sulfur batteries Energy Storage Materials. 15: 388-395. DOI: 10.1016/J.Ensm.2018.08.019  0.774
2018 Udangawa WMRN, Willard CF, Mancinelli C, Chapman C, Linhardt RJ, Simmons TJ. Coconut oil-cellulose beaded microfibers by coaxial electrospinning: An eco-model system to study thermoregulation of confined phase change materials Cellulose. 26: 1855-1868. DOI: 10.1007/S10570-018-2151-2  0.762
2017 Hou L, Zhang X, Mikael PE, Lin L, Dong W, Zheng Y, Simmons TJ, Zhang F, Linhardt RJ. Biodegradable and Bioactive PCL-PGS Core-Shell Fibers for Tissue Engineering. Acs Omega. 2: 6321-6328. PMID 30023516 DOI: 10.1021/acsomega.7b00460  0.772
2017 Zhang X, Pagadala V, Jester HM, Lim AM, Pham TQ, Goulas AMP, Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists. Chemical Science. 8: 7932-7940. PMID 29568440 DOI: 10.1039/C7Sc03541A  0.496
2017 Sun X, Tao L, Yi L, Ouyang Y, Xu N, Li D, Linhardt RJ, Zhang Z. N-glycans released from glycoproteins using a commercial kit and comprehensively analyzed with a hypothetical database. Journal of Pharmaceutical Analysis. 7: 87-94. PMID 29404022 DOI: 10.1016/J.Jpha.2017.01.004  0.585
2017 Agyekum I, Pepi L, Yu Y, Li J, Yan L, Linhardt RJ, Chen S, Amster IJ. Structural elucidation of fucosylated chondroitin sulfates from sea cucumber using FTICR-MS/MS. European Journal of Mass Spectrometry (Chichester, England). 1469066717731900. PMID 29232996 DOI: 10.1177/1469066717731900  0.796
2017 Ming SA, Cottman-Thomas E, Black NC, Chen Y, Veeramachineni V, Peterson DC, Chen X, Tedaldi LM, Wagner GK, Cai C, Linhardt RJ, Vann WF. Interaction of Neisseria meningitidis Group X N-Acetylglucosamine-1-phosphotransferase with Its Donor Substrate. Glycobiology. PMID 29228283 DOI: 10.1093/Glycob/Cwx100  0.523
2017 Middleton DR, Zhang X, Wantuch PL, Ozdilek A, Liu X, Lopilato R, Gangasani N, Bridger R, Wells L, Linhardt RJ, Avci FY. Identification and characterization of the Streptococcus pneumoniae type 3 capsule-specific glycoside hydrolase of Paenibacillus species 32352. Glycobiology. PMID 29190349 DOI: 10.1093/Glycob/Cwx097  0.749
2017 Li J, Qian S, Xiong L, Zhu C, Shu M, Wang J, Jiao Y, He H, Zhang F, Linhardt RJ, Zhong W. Comparative Genomics Reveals Specific Genetic Architectures in Nicotine Metabolism of Pseudomonas sp. JY-Q. Frontiers in Microbiology. 8: 2085. PMID 29163390 DOI: 10.3389/Fmicb.2017.02085  0.648
2017 Pan Y, Wang P, Zhang F, Yu Y, Zhang X, Lin L, Linhardt RJ. Glycosaminoglycans from fish swim bladder: isolation, structural characterization and bioactive potential. Glycoconjugate Journal. PMID 29124565 DOI: 10.1007/S10719-017-9804-5  0.793
2017 Lin YP, Li L, Zhang F, Linhardt RJ. Borrelia burgdorferi glycosaminoglycan-binding proteins: a potential target for new therapeutics against Lyme disease. Microbiology (Reading, England). PMID 29116038 DOI: 10.1099/Mic.0.000571  0.501
2017 Yu Y, Duan J, Leach Iii FE, Toida T, Higashi K, Zhang H, Zhang F, Amster IJ, Linhardt RJ. Sequencing the Dermatan Sulfate Chain of Decorin. Journal of the American Chemical Society. PMID 29111696 DOI: 10.1021/Jacs.7B10164  0.768
2017 Yan L, Li J, Wang D, Ding T, Hu Y, Ye X, Linhardt RJ, Chen S. Molecular size is important for the safety and selective inhibition of intrinsic factor Xase for fucosylated chondroitin sulfate. Carbohydrate Polymers. 178: 180-189. PMID 29050584 DOI: 10.1016/J.Carbpol.2017.09.034  0.55
2017 Fu L, Li K, Mori D, Hirakane M, Lin L, Grover N, Datta P, Yu Y, Zhao J, Zhang F, Yalcin M, Mousa SA, Dordick JS, Linhardt RJ. Enzymatic generation of highly anticoagulant bovine intestinal heparin. Journal of Medicinal Chemistry. PMID 28972371 DOI: 10.1021/Acs.Jmedchem.7B01269  0.797
2017 Ouyang Y, Zeng Y, Yi L, Tang H, Li D, Linhardt RJ, Zhang Z. Qualitative and quantitative analysis of heparin and low molecular weight heparins using size exclusion chromatography with multiple angle laser scattering/refractive index and inductively coupled plasma/mass spectrometry detectors. Journal of Chromatography. A. PMID 28958760 DOI: 10.1016/J.Chroma.2017.09.040  0.609
2017 Wen P, Wen Y, Zong M, Linhardt RJ, Wu H. Encapsulation of bioactive compound in electrospun fibers and its potential application. Journal of Agricultural and Food Chemistry. PMID 28949530 DOI: 10.1021/Acs.Jafc.7B02956  0.37
2017 Liu Z, Song L, Zhang F, He W, Linhardt RJ. Characteristics of global organic matrix in normal and pimpled chicken eggshells. Poultry Science. 96: 3775-3784. PMID 28938773 DOI: 10.3382/Ps/Pex171  0.777
2017 Xu Y, Chandarajoti K, Zhang X, Pagadala V, Dou W, Hoppensteadt DM, Sparkenbaugh EM, Cooley B, Daily S, Key NS, Severynse-Stevens D, Fareed J, Linhardt RJ, Pawlinski R, Liu J. Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins. Science Translational Medicine. 9. PMID 28878012 DOI: 10.1126/Scitranslmed.Aan5954  0.472
2017 Li G, Li L, Joo EJ, Son JW, Kim YJ, Kang JK, Lee KB, Zhang F, Linhardt RJ. Glycosaminoglycans and glycolipids as potential biomarkers in lung cancer. Glycoconjugate Journal. PMID 28822024 DOI: 10.1007/S10719-017-9790-7  0.773
2017 Zhang X, Green DE, Schultz VL, Lin L, Han X, Wang R, Yaksic A, Kim SY, DeAngelis PL, Linhardt RJ. Synthesis of 4-azido-N-acetylhexosamine uridine diphosphate donors: Clickable glycosaminoglycans. The Journal of Organic Chemistry. PMID 28813597 DOI: 10.1021/Acs.Joc.7B01787  0.646
2017 Li J, Li S, Yan L, Ding T, Linhardt RJ, Yu Y, Liu X, Liu D, Ye X, Chen S. Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation: Importance of sulfation pattern and molecular size. European Journal of Medicinal Chemistry. 139: 191-200. PMID 28800457 DOI: 10.1016/J.Ejmech.2017.07.065  0.768
2017 Williams A, He W, Cress BF, Liu X, Alexandria J, Yoshizawa H, Nishimura K, Toida T, Koffas M, Linhardt RJ. Cloning and expression of recombinant chondroitinase AC II and its comparison to the Arthrobacter aurescens enzyme. Biotechnology Journal. PMID 28799715 DOI: 10.1002/Biot.201700239  0.788
2017 He W, Zhu Y, Shirke A, Sun X, Liu J, Gross RA, Koffas MAG, Linhardt RJ, Li M. Expression of chondroitin-4-O-sulfotransferase in Escherichia coli and Pichia pastoris. Applied Microbiology and Biotechnology. PMID 28761999 DOI: 10.1007/S00253-017-8411-5  0.791
2017 Liu Z, Song L, Lu L, Zhang X, Zhang F, Wang K, Linhardt RJ. Comparative proteomics of matrix fractions between pimpled and normal chicken eggshells. Journal of Proteomics. PMID 28755913 DOI: 10.1016/J.Jprot.2017.07.015  0.779
2017 Wang H, He W, Jiang P, Yu Y, Lin L, Sun X, Koffas M, Zhang F, Linhardt RJ. Construction and functional characterization of truncated versions of recombinant keratanase II from Bacillus circulans. Glycoconjugate Journal. PMID 28752383 DOI: 10.1007/S10719-017-9786-3  0.778
2017 Li S, Li J, Zhi Z, Wei C, Wang W, Ding T, Ye X, Hu Y, Linhardt RJ, Chen S. Macromolecular properties and hypolipidemic effects of four sulfated polysaccharides from sea cucumbers. Carbohydrate Polymers. 173: 330-337. PMID 28732873 DOI: 10.1016/J.Carbpol.2017.05.063  0.541
2017 Fulcher YG, Prior SH, Masuko S, Li L, Pu D, Zhang F, Linhardt RJ, Van Doren SR. Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7. Structure (London, England : 1993). PMID 28648610 DOI: 10.1016/J.Str.2017.05.019  0.675
2017 Jones JA, Vernacchio VR, Collins SM, Shirke AN, Xiu Y, Englaender JA, Cress BF, McCutcheon CC, Linhardt RJ, Gross RA, Koffas MAG. Complete Biosynthesis of Anthocyanins Using E. coli Polycultures. Mbio. 8. PMID 28588129 DOI: 10.1128/Mbio.00621-17  0.77
2017 Dumont CM, Piselli J, Kazi N, Bowman E, Li G, Linhardt RJ, Temple S, Dai G, Thompson DM. Factors released from endothelial cells exposed to flow impact adhesion, proliferation, and fate choice in the adult neural stem cell lineage. Stem Cells and Development. PMID 28557666 DOI: 10.1089/Scd.2016.0350  0.605
2017 Yu Y, Hirakane M, Mori D, Lin L, Zhang F, Zhang H, Linhardt RJ. Structural and activity variability of fractions with different charge density and chain length from pharmaceutical heparins. Glycoconjugate Journal. PMID 28555433 DOI: 10.1007/S10719-017-9774-7  0.775
2017 Xiu Y, Jang S, Jones JA, Zill NA, Linhardt RJ, Yuan Q, Jung GY, Koffas MAG. Naringenin-Responsive Riboswitch-Based Fluorescent Biosensor Module for Escherichia coli Co-cultures. Biotechnology and Bioengineering. PMID 28543037 DOI: 10.1002/Bit.26340  0.773
2017 Wang W, Zhang C, Sun X, Su S, Li Q, Linhardt RJ. Efficient, environmentally-friendly and specific valorization of lignin: promising role of non-radical lignolytic enzymes. World Journal of Microbiology & Biotechnology. 33: 125. PMID 28540631 DOI: 10.1007/S11274-017-2286-6  0.62
2017 Xie Q, Spear JM, Noble AJ, Sousa DR, Meyer NL, Davulcu O, Zhang F, Linhardt RJ, Stagg SM, Chapman MS. The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide. Molecular Therapy. Methods & Clinical Development. 5: 1-12. PMID 28480299 DOI: 10.1016/J.Omtm.2017.02.004  0.523
2017 Kim SY, Li B, Linhardt RJ. Pathogenesis and Inhibition of Flaviviruses from a Carbohydrate Perspective. Pharmaceuticals (Basel, Switzerland). 10. PMID 28471403 DOI: 10.3390/Ph10020044  0.475
2017 Su G, Li L, Huang H, Zhong W, Yu P, Zhang F, Linhardt RJ. Corrigendum to "Production of a low molecular weight heparin production using recombinant glycuronidas"[Carbohydr. Polym., 134 (2015) 151-157]. Carbohydrate Polymers. 167: 364. PMID 28433174 DOI: 10.1016/J.Carbpol.2017.03.055  0.668
2017 Wei CY, Liao NB, Zhang Y, Ye XQ, Li S, Hu YQ, Liu DH, Linhardt RJ, Wang X, Chen SG. In vitro fermentation behaviors of fucosylated chondroitin sulfate from Pearsonothuria graeffei by human gut microflora. International Journal of Biological Macromolecules. PMID 28431945 DOI: 10.1016/J.Ijbiomac.2017.04.036  0.534
2017 Zhi Z, Chen J, Li S, Wang W, Huang R, Liu D, Ding T, Linhardt RJ, Chen S, Ye X. Fast preparation of RG-I enriched ultra-low molecular weight pectin by an ultrasound accelerated Fenton process. Scientific Reports. 7: 541. PMID 28373642 DOI: 10.1038/S41598-017-00572-3  0.554
2017 Sommers CD, Ye H, Liu J, Linhardt RJ, Keire DA. Heparin and homogeneous model heparin oligosaccharides form distinct complexes with protamine: Light scattering and zeta potential analysis. Journal of Pharmaceutical and Biomedical Analysis. 140: 113-121. PMID 28346881 DOI: 10.1016/J.Jpba.2017.03.010  0.379
2017 Lane RS, St Ange K, Zolghadr B, Liu X, Schäffer C, Linhardt RJ, DeAngelis PL. Expanding glycosaminoglycan chemical space: towards the creation of sulfated analogs, novel polymers and chimeric constructs. Glycobiology. 1-11. PMID 28334971 DOI: 10.1093/Glycob/Cwx021  0.552
2017 Zhao J, Liu X, Malhotra A, Li Q, Zhang F, Linhardt RJ. Novel method for measurement of heparin anticoagulant activity using SPR. Analytical Biochemistry. 526: 39-42. PMID 28322799 DOI: 10.1016/J.Ab.2017.03.013  0.669
2017 Vongchan P, Linhardt RJ. Characterization of a new monoclonal anti-glypican-3 antibody specific to the hepatocellular carcinoma cell line, HepG2. World Journal of Hepatology. 9: 368-384. PMID 28321273 DOI: 10.4254/Wjh.V9.I7.368  0.72
2017 Zhao J, Huvent I, Lippens G, Eliezer D, Zhang A, Li Q, Tessier P, Linhardt RJ, Zhang F, Wang C. Glycan Determinants of Heparin-Tau Interaction. Biophysical Journal. 112: 921-932. PMID 28297651 DOI: 10.1016/J.Bpj.2017.01.024  0.762
2017 Zhao J, Zhang F, Liu X, St Ange K, Zhang A, Li Q, Linhardt RJ. Isolation of a lectin binding rhamnogalacturonan-I containing pectic polysaccharide from pumpkin. Carbohydrate Polymers. 163: 330-336. PMID 28267513 DOI: 10.1016/J.Carbpol.2017.01.067  0.798
2017 Zhu Y, Liang X, Zhang H, Feng W, Liu Y, Zhang F, Linhardt RJ. A comparative secretome analysis of industrial Aspergillus oryzae and its spontaneous mutant ZJGS-LZ-21. International Journal of Food Microbiology. 248: 1-9. PMID 28237882 DOI: 10.1016/J.Ijfoodmicro.2017.02.003  0.785
2017 Liu X, St Ange K, Wang X, Lin L, Zhang F, Chi L, Linhardt RJ. Parent heparin and daughter LMW heparin correlation analysis using LC-MS and NMR. Analytica Chimica Acta. 961: 91-99. PMID 28224913 DOI: 10.1016/J.Aca.2017.01.042  0.798
2017 Yang Y, Haeger SM, Suflita MA, Zhang F, Dailey KL, Colbert JF, Ford JA, Picon MA, Stearman RS, Lin L, Liu X, Han X, Linhardt RJ, Schmidt EP. Fibroblast Growth Factor Signaling Mediates Pulmonary Endothelial Glycocalyx Reconstitution. American Journal of Respiratory Cell and Molecular Biology. PMID 28187268 DOI: 10.1165/Rcmb.2016-0338Oc  0.763
2017 Minteer CJ, Siegart NM, Colelli KM, Liu X, Linhardt RJ, Wang C, Gomez AV, Reitter JN, Mills KV. Intein-promoted cyclization of aspartic acid flanking the intein leads to atypical N-terminal cleavage. Biochemistry. PMID 28165720 DOI: 10.1021/Acs.Biochem.6B00894  0.532
2017 Kim SY, Zhao J, Liu X, Fraser K, Lin L, Zhang X, Zhang F, Dordick JS, Linhardt RJ. Interaction of Zika Virus Envelope Protein with Glycosaminoglycans. Biochemistry. PMID 28151637 DOI: 10.1021/Acs.Biochem.6B01056  0.768
2017 Schultz VL, Zhang X, Linkens K, Rimel J, Green DE, DeAngelis PL, Linhardt RJ. Chemoenzymatic Synthesis of 4-Fluoro-N-Acetylhexosamine Uridine Diphosphate Donors: Chain Terminators in Glycosaminoglycan Synthesis. The Journal of Organic Chemistry. PMID 28128958 DOI: 10.1021/Acs.Joc.6B02929  0.379
2017 Yang J, Hsieh PH, Liu X, Zhou W, Zhang X, Zhao J, Xu Y, Zhang F, Linhardt RJ, Liu J. Construction and characterisation of a heparan sulphate heptasaccharide microarray. Chemical Communications (Cambridge, England). PMID 28106177 DOI: 10.1039/C6Cc08204A  0.708
2017 Cress BF, Leitz QD, Kim DC, Amore TD, Suzuki JY, Linhardt RJ, Koffas MA. CRISPRi-mediated metabolic engineering of E. coli for O-methylated anthocyanin production. Microbial Cell Factories. 16: 10. PMID 28095853 DOI: 10.1186/S12934-016-0623-3  0.705
2017 Zhang X, Xu Y, Hsieh PH, Liu J, Lin L, Schmidt EP, Linhardt RJ. Chemoenzymatic synthesis of unmodified heparin oligosaccharides: cleavage of p-nitrophenyl glucuronide by alkaline and Smith degradation. Organic & Biomolecular Chemistry. PMID 28091666 DOI: 10.1039/C6Ob02603F  0.649
2017 Liu X, St Ange K, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Chi L, Jin C, Jin Y, Yao Y, Linhardt RJ. Comparison of Low-Molecular-Weight Heparins Prepared From Bovine Heparins With Enoxaparin. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 1076029616686422. PMID 28056526 DOI: 10.1177/1076029616686422  0.738
2017 Englaender JA, Jones JA, Cress BF, Kuhlman TE, Linhardt RJ, Koffas MA. Effect of Genomic Integration Location on Heterologous Protein Expression and Metabolic Engineering in E. coli. Acs Synthetic Biology. PMID 28055177 DOI: 10.1021/Acssynbio.6B00350  0.769
2017 Tao L, Song F, Xu N, Li D, Linhardt RJ, Zhang Z. New insights into the action of bacterial chondroitinase AC I and hyaluronidase on hyaluronic acid. Carbohydrate Polymers. 158: 85-92. PMID 28024546 DOI: 10.1016/J.Carbpol.2016.12.010  0.59
2017 Chen Y, St Ange K, Lin L, Liu X, Zhang X, Linhardt RJ. Quantitative analysis of the major linkage region tetrasaccharides in heparin. Carbohydrate Polymers. 157: 244-250. PMID 27987924 DOI: 10.1016/J.Carbpol.2016.09.081  0.744
2017 Hao J, Xu S, Xu N, Li D, Linhardt RJ, Zhang Z. Impact of degree of oxidation on the physicochemical properties of microcrystalline cellulose. Carbohydrate Polymers. 155: 483-490. PMID 27702538 DOI: 10.1016/J.Carbpol.2016.09.012  0.571
2017 Yu Y, Zang N, Zhang F, Linhardt RJ, Zhang H. Proteome Analysis on Proteins Sequentially Extracted from Loach (Misgurnus anguillicaudatus) Biochemistry & Physiology: Open Access. 6. DOI: 10.4172/2168-9652.1000214  0.544
2017 Wang F, Ma Y, Liu Y, Zhang X, Zhang F, Linhardt RJ. Improved octyl glucoside synthesis using immobilized β-glucosidase on PA-M with reduced glucose surplus inhibition Biocatalysis and Biotransformation. 35: 349-362. DOI: 10.1080/10242422.2017.1345886  0.496
2017 Chen J, Cheng H, Wu D, Linhardt RJ, Zhi Z, Yan L, Chen S, Ye X. Green recovery of pectic polysaccharides from citrus canning processing water Journal of Cleaner Production. 144: 459-469. DOI: 10.1016/J.Jclepro.2016.12.140  0.503
2017 Chen Y, St.Ange K, Lin L, Liu X, Zhang X, Linhardt RJ. Quantitative analysis of the major linkage region tetrasaccharides in heparin Carbohydrate Polymers. 157: 244-250. DOI: 10.1016/j.carbpol.2016.09.081  0.432
2016 Hou L, Udangawa WMRN, Pochiraju A, Dong W, Zheng Y, Linhardt RJ, Simmons TJ. Synthesis of Heparin-Immobilized, Magnetically Addressable Cellulose Nanofibers for Biomedical Applications. Acs Biomaterials Science & Engineering. 2: 1905-1913. PMID 33440527 DOI: 10.1021/acsbiomaterials.6b00273  0.775
2016 Schultz V, Suflita M, Liu X, Zhang X, Yu Y, Li L, Green DE, Xu Y, Zhang F, DeAngelis PL, Liu J, Linhardt RJ. Heparan sulfate domains required for fibroblast growth factor 1 and 2 signaling through fibroblast growth factor receptor 1c. The Journal of Biological Chemistry. PMID 28031461 DOI: 10.1074/Jbc.M116.761585  0.78
2016 Liu LP, Zong MH, Linhardt RJ, Lou WY, Li N, Huang C, Wu H. Mechanistic insights into the effect of imidazolium ionic liquid on lipid production by Geotrichum fermentans. Biotechnology For Biofuels. 9: 266. PMID 28018484 DOI: 10.1186/S13068-016-0682-Z  0.37
2016 Liu X, St Ange K, Lin L, Zhang F, Chi L, Linhardt RJ. Top-down and bottom-up analysis of commercial enoxaparins. Journal of Chromatography. A. PMID 28011077 DOI: 10.1016/J.Chroma.2016.12.021  0.801
2016 Chen Y, Lin L, Agyekum I, Zhang X, St Ange K, Yu Y, Zhang F, Liu J, Amster IJ, Linhardt RJ. Structural Analysis of Heparin-Derived 3-O-Sulfated Tetrasaccharides: Antithrombin Binding Site Variants. Journal of Pharmaceutical Sciences. PMID 28007564 DOI: 10.1016/J.Xphs.2016.11.023  0.79
2016 Ibrahim MH, Cress BF, Linhardt RJ, Koffas MA, Gross RA. Draft Genome Sequence of Bacillus subtilis Ia1a, a New Strain for Poly-γ-Glutamic Acid and Exopolysaccharide Production. Genome Announcements. 4. PMID 27979935 DOI: 10.1128/Genomea.01361-16  0.732
2016 Englaender JA, Zhu Y, Shirke AN, Lin L, Liu X, Zhang F, Gross RA, Koffas MA, Linhardt RJ. Expression and secretion of glycosylated heparin biosynthetic enzymes using Komagataella pastoris. Applied Microbiology and Biotechnology. PMID 27975137 DOI: 10.1007/S00253-016-8047-X  0.781
2016 Li P, Linhardt RJ, Cao Z. Structural Characterization of Oligochitosan Elicitor from Fusarium sambucinum and Its Elicitation of Defensive Responses in Zanthoxylum bungeanum. International Journal of Molecular Sciences. 17. PMID 27973408 DOI: 10.3390/Ijms17122076  0.717
2016 Wang X, Liu X, Li L, Zhang F, Hu M, Ren F, Chi L, Linhardt RJ. GlycCompSoft: Software for Automated Comparison of Low Molecular Weight Heparins Using Top-Down LC/MS Data. Plos One. 11: e0167727. PMID 27942011 DOI: 10.1371/Journal.Pone.0167727  0.787
2016 Sun X, Guo Z, Yu M, Lin C, Sheng A, Wang Z, Linhardt RJ, Chi L. Hydrophilic interaction chromatography-multiple reaction monitoring mass spectrometry method for basic building block analysis of low molecular weight heparins prepared through nitrous acid depolymerization. Journal of Chromatography. A. PMID 27923477 DOI: 10.1016/J.Chroma.2016.11.061  0.807
2016 Kwon SJ, Na DH, Kwak JH, Douaisi M, Zhang F, Park EJ, Park JH, Youn H, Song CS, Kane RS, Dordick JS, Lee KB, Linhardt RJ. Nanostructured glycan architecture is important in the inhibition of influenza A virus infection. Nature Nanotechnology. PMID 27775724 DOI: 10.1038/Nnano.2016.181  0.599
2016 Chen Y, Reddy M, Yu Y, Zhang F, Linhardt RJ. Glycosaminoglycans from chicken muscular stomach or gizzard. Glycoconjugate Journal. PMID 27752801 DOI: 10.1007/S10719-016-9737-4  0.738
2016 Yu Y, Chen Y, Mikael P, Zhang F, Stalcup AM, German R, Gould F, Ohlemacher J, Zhang H, Linhardt RJ. Surprising absence of heparin in the intestinal mucosa of baby pigs. Glycobiology. PMID 27744271 DOI: 10.1093/Glycob/Cww104  0.783
2016 Zhao Y, Singh A, Xu Y, Zong C, Zhang F, Boons GJ, Liu J, Linhardt RJ, Woods RJ, Amster IJ. Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study. Journal of the American Society For Mass Spectrometry. PMID 27663556 DOI: 10.1007/S13361-016-1496-8  0.562
2016 Li JH, Li S, Zhi ZJ, Yan LF, Ye XQ, Ding T, Yan L, Linhardt RJ, Chen SG. Depolymerization of Fucosylated Chondroitin Sulfate with a Modified Fenton-System and Anticoagulant Activity of the Resulting Fragments. Marine Drugs. 14. PMID 27657094 DOI: 10.3390/Md14090170  0.562
2016 Imamura M, Higashi K, Yamaguchi K, Asakura K, Furihata T, Terui Y, Satake T, Maegawa J, Yasumura K, Ibuki A, Akase T, Nishimura K, Kashiwagi K, Linhardt RJ, Igarashi K, et al. Polyamines release the let-7b-mediated suppression of initiation codon recognition during the protein synthesis of EXT2. Scientific Reports. 6: 33549. PMID 27650265 DOI: 10.1038/Srep33549  0.554
2016 Higashi K, Takeda K, Mukuno A, Okamoto Y, Masuko S, Linhardt RJ, Toida T. Identification of Keratan Sulfate Disaccharide at C-3 position of Glucuronate of Chondroitin Sulfate from Mactra Chinensis. The Biochemical Journal. PMID 27647934 DOI: 10.1042/Bcj20160655  0.709
2016 Ulaganathan T, Shi R, Yao D, Gu RX, Garron ML, Cherney M, Tieleman DP, Sterner E, Li G, Li L, Linhardt RJ, Cygler M. Conformational Flexibility of PL12 family Heparinases: Structure and Substrate Specificity of Heparinase III from Bacteroides thetaiotaomicron (BT4657). Glycobiology. PMID 27621378 DOI: 10.1093/Glycob/Cww096  0.794
2016 Wang YJ, Lin L, Zhang X, Schultz V, Zhang F, Sun JZ, Linhardt RJ. Selective, switchable fluorescent probe for heparin based on aggregation-induced emission. Analytical Biochemistry. PMID 27619488 DOI: 10.1016/J.Ab.2016.09.007  0.667
2016 He P, Zhang A, Zhou S, Zhang F, Linhardt RJ, Sun P. Structural elucidation of polysaccharide containing 3-O-methyl galactose from fruiting bodies of Pleurotus citrinopileatus. Carbohydrate Research. 434: 72-76. PMID 27599128 DOI: 10.1016/J.Carres.2016.08.006  0.785
2016 Rubinson KA, Chen Y, Cress BF, Zhang F, Linhardt RJ. Heparin's Solution Structure Determined by Small-Angle Neutron Scattering (SANS). Biopolymers. PMID 27543274 DOI: 10.1002/Bip.22936  0.777
2016 He P, Zhang A, Zhang F, Linhardt RJ, Sun P. Structure and bioactivity of a polysaccharide containing uronic acid from Polyporus umbellatus sclerotia. Carbohydrate Polymers. 152: 222-30. PMID 27516268 DOI: 10.1016/J.Carbpol.2016.07.010  0.798
2016 Zhao J, Liu X, Kao C, Zhang EK, Li Q, Zhang F, Linhardt RJ. Kinetic and Structural Studies on Interactions between Glycosaminoglycans and Langerin. Biochemistry. PMID 27447199 DOI: 10.1021/Acs.Biochem.6B00555  0.68
2016 Sun X, Sheng A, Liu X, Shi F, Jin L, Xie S, Zhang F, Linhardt RJ, Chi L. Comprehensive identification and quantitation of basic building blocks for low molecular weight heparin. Analytical Chemistry. PMID 27388010 DOI: 10.1021/Acs.Analchem.6B01709  0.807
2016 Dimitrievska S, Gui L, Weyers A, Lin T, Cai C, Woo W, Tuggle CT, Sundaram S, Balestrini JL, Slattery D, Tchouta L, Kyriakides TR, Tarbell JM, Linhardt RJ, Niklason LE. New Functional Tools for Antithrombogenic Activity Assessment of Live Surface Glycocalyx. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27386939 DOI: 10.1161/Atvbaha.116.308023  0.767
2016 Oduah EI, Linhardt RJ, Sharfstein ST. Heparin: Past, Present, and Future. Pharmaceuticals (Basel, Switzerland). 9. PMID 27384570 DOI: 10.3390/Ph9030038  0.319
2016 Lin L, Liu X, Zhang F, Chi L, Amster IJ, Leach FE, Xia Q, Linhardt RJ. Analysis of heparin oligosaccharides by capillary electrophoresis-negative-ion electrospray ionization mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 27325464 DOI: 10.1007/S00216-016-9662-1  0.794
2016 Mulloy B, Wu N, Gyapon-Quast F, Lin L, Zhang F, Pickering MC, Linhardt RJ, Feizi T, Chai W. Abnormally high content of free glucosamine residues identified in a preparation of commercially available porcine intestinal heparan sulfate. Analytical Chemistry. PMID 27295282 DOI: 10.1021/Acs.Analchem.6B01662  0.685
2016 Liu Z, Sun X, Cai C, He W, Zhang F, Linhardt RJ. Characteristics of glycosaminoglycans in chicken eggshells and the influence of disaccharide composition on eggshell properties. Poultry Science. PMID 27287383 DOI: 10.3382/Ps/Pew179  0.776
2016 Szajek AY, Chess E, Johansen K, Gratzl G, Gray E, Keire D, Linhardt RJ, Liu J, Morris T, Mulloy B, Nasr M, Shriver Z, Torralba P, Viskov C, Williams R, et al. The US regulatory and pharmacopeia response to the global heparin contamination crisis. Nature Biotechnology. 34: 625-630. PMID 27281424 DOI: 10.1038/Nbt.3606  0.697
2016 Guan Y, Xu X, Liu X, Sheng A, Jin L, Linhardt RJ, Chi L. Comparison of Low-Molecular-Weight Heparins Prepared From Bovine Lung Heparin and Porcine Intestine Heparin. Journal of Pharmaceutical Sciences. 105: 1843-50. PMID 27238483 DOI: 10.1016/J.Xphs.2016.03.037  0.802
2016 Zhang X, Khalidi O, Kim SY, Wang R, Schultz V, Cress BF, Gross RA, Koffas MA, Linhardt RJ. Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents. Bioorganic & Medicinal Chemistry Letters. PMID 27210435 DOI: 10.1016/J.Bmcl.2016.05.003  0.77
2016 Koh A, Linhardt RJ, Gross RA. Effect of sophorolipid n-alkyl ester chain length on its interfacial properties at the almond oil-water interface. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27159768 DOI: 10.1021/Acs.Langmuir.6B01008  0.449
2016 Ge D, Higashi K, Ito D, Nagano K, Ishikawa R, Terui Y, Higashi K, Moribe K, Linhardt RJ, Toida T. Poly-ion Complex of Chondroitin Sulfate and Spermine and Its Effect on Oral Chondroitin Sulfate Bioavailability. Chemical & Pharmaceutical Bulletin. 64: 390-8. PMID 27150471 DOI: 10.1248/Cpb.C15-00940  0.543
2016 Hao J, Lu J, Xu N, Linhardt RJ, Zhang Z. Specific oxidation pattern of soluble starch with TEMPO-NaBr-NaClO system. Carbohydrate Polymers. 146: 238-44. PMID 27112871 DOI: 10.1016/J.Carbpol.2016.03.040  0.555
2016 Onishi A, St Ange K, Dordick JS, Linhardt RJ. Heparin and anticoagulation. Frontiers in Bioscience (Landmark Edition). 21: 1372-92. PMID 27100512  0.573
2016 St Ange K, Onishi A, Fu L, Sun X, Lin L, Mori D, Zhang F, Dordick JS, Fareed J, Hoppensteadt D, Jeske W, Linhardt RJ. Analysis of Heparins Derived From Bovine Tissues and Comparison to Porcine Intestinal Heparins. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. PMID 27084870 DOI: 10.1177/1076029616643822  0.802
2016 Cress BF, Jones JA, Kim DC, Leitz QD, Englaender JA, Collins SM, Linhardt RJ, Koffas MA. Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli. Nucleic Acids Research. PMID 27079979 DOI: 10.1093/Nar/Gkw231  0.771
2016 Huang H, Liu X, Lv S, Zhong W, Zhang F, Linhardt RJ. Recombinant Escherichia coli K5 strain with the deletion of waaR gene decreases the molecular weight of the heparosan capsular polysaccharide. Applied Microbiology and Biotechnology. PMID 27079575 DOI: 10.1007/S00253-016-7511-Y  0.676
2016 Schmidt EP, Overdier KH, Sun X, Lin L, Liu X, Yang Y, Ammons LA, Hiller TD, Suflita MA, Yu Y, Chen Y, Zhang F, Cothren Burlew C, Edelstein CL, Douglas IS, ... Linhardt RJ, et al. Urinary Glycosaminoglycans Predict Outcomes in Septic Shock and ARDS. American Journal of Respiratory and Critical Care Medicine. PMID 26926297 DOI: 10.1164/Rccm.201511-2281Oc  0.751
2016 Fu L, Sun X, He W, Cai C, Onishi A, Zhang F, Linhardt RJ, Liu Z. Keratan sulfate glycosaminoglycan from chicken egg white. Glycobiology. PMID 26903438 DOI: 10.1093/Glycob/Cww017  0.782
2016 Zheng Y, Miao J, Zhang F, Cai C, Koh A, Simmons TJ, Mousa SA, Linhardt RJ. Surface modification of a polyethylene film for anticoagulant and anti-microbial catheter. Reactive & Functional Polymers. 100: 142-150. PMID 26900340 DOI: 10.1016/J.Reactfunctpolym.2016.01.013  0.769
2016 Fox JC, Tyler RC, Peterson FC, Dyer DP, Zhang F, Linhardt RJ, Handel TM, Volkman BF. Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer. Biochemistry. PMID 26836755 DOI: 10.1021/Acs.Biochem.5B01329  0.517
2016 Zheng Y, Cai C, Zhang F, Monty J, Linhardt RJ, Simmons TJ. Can natural fibers be a silver bullet? Antibacterial cellulose fibers through the covalent bonding of silver nanoparticles to electrospun fibers. Nanotechnology. 27: 055102. PMID 26751520 DOI: 10.1088/0957-4484/27/5/055102  0.77
2016 Ouyang Y, Wu C, Sun X, Liu J, Linhardt RJ, Zhang Z. Development of hydrophilic interaction chromatography with quadruple time-of-flight mass spectrometry for heparin and low molecular weight heparin disaccharide analysis. Rapid Communications in Mass Spectrometry : Rcm. 30: 277-84. PMID 26689158 DOI: 10.1002/Rcm.7437  0.603
2016 Wang F, Ma Y, Liu Y, Cui Z, Ying X, Zhang F, Linhardt RJ. A simple strategy for the separation and purification of water-soluble polysaccharides from the fresh Spirulina platensis Separation Science and Technology. 52: 456-466. DOI: 10.1080/01496395.2016.1244549  0.49
2016 Hou L, Udangawa WMRN, Pochiraju A, Dong W, Zheng Y, Linhardt RJ, Simmons TJ. Synthesis of Heparin-Immobilized, Magnetically Addressable Cellulose Nanofibers for Biomedical Applications Acs Biomaterials Science & Engineering. 2: 1905-1913. DOI: 10.1021/Acsbiomaterials.6B00273  0.77
2016 Zheng Y, Miao J, Zhang F, Cai C, Koh A, Simmons TJ, Mousa SA, Linhardt RJ. Surface modification of a polyethylene film for anticoagulant and antimicrobial catheter Reactive and Functional Polymers. 100: 142-150. DOI: 10.1016/j.reactfunctpolym.2016.01.013  0.756
2016 Janke JJ, Zhang F, Linhardt RJ, Garcia AE. Heparin-Sclerostin Interactions from Surface Plasmon Resonance and Molecular Dynamics Simulations Biophysical Journal. 110: 544a. DOI: 10.1016/J.Bpj.2015.11.2912  0.604
2016 Maiorana A, Subramaniam B, Centore R, Han X, Linhardt RJ, Gross RA. Synthesis and characterization of an adipic acid-derived epoxy resin Journal of Polymer Science Part a: Polymer Chemistry. 54: 2625-2631. DOI: 10.1002/Pola.28142  0.471
2015 Sun X, Lin L, Liu X, Zhang F, Chi L, Xia Q, Linhardt RJ. Capillary Electrophoresis-Mass Spectrometry for the Analysis of Heparin Oligosaccharides and Low Molecular Weight Heparin. Analytical Chemistry. PMID 26714061 DOI: 10.1021/Acs.Analchem.5B04405  0.799
2015 Ucakturk E, Akman O, Sun X, Baydar DE, Dolgun A, Zhang F, Linhardt RJ. Changes in composition and sulfation patterns of glycoaminoglycans in renal cell carcinoma. Glycoconjugate Journal. PMID 26662466 DOI: 10.1007/S10719-015-9643-1  0.762
2015 Fu L, Suflita M, Linhardt RJ. Bioengineered heparins and heparan sulfates. Advanced Drug Delivery Reviews. PMID 26555370 DOI: 10.1016/J.Addr.2015.11.002  0.801
2015 Yi L, Ouyang Y, Sun X, Xu N, Linhardt RJ, Zhang Z. Qualitative and quantitative analysis of branches in dextran using high-performance anion exchange chromatography coupled to quadrupole time-of-flight mass spectrometry. Journal of Chromatography. A. PMID 26530145 DOI: 10.1016/J.Chroma.2015.10.064  0.584
2015 Cress BF, Trantas EA, Ververidis F, Linhardt RJ, Koffas MA. Sensitive cells: enabling tools for static and dynamic control of microbial metabolic pathways. Current Opinion in Biotechnology. 36: 205-214. PMID 26453934 DOI: 10.1016/J.Copbio.2015.09.007  0.685
2015 Higashi K, Okamoto Y, Mukuno A, Wakai J, Hosoyama S, Linhardt RJ, Toida T. Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue. Carbohydrate Polymers. 134: 557-65. PMID 26428158 DOI: 10.1016/J.Carbpol.2015.07.082  0.557
2015 Su G, Li L, Huang H, Zhong W, Yu P, Zhang F, Linhardt RJ. Production of a low molecular weight heparin production using recombinant glycuronidase. Carbohydrate Polymers. 134: 151-7. PMID 26428111 DOI: 10.1016/J.Carbpol.2015.08.001  0.695
2015 Zhang F, Zhang J, Linhardt RJ. Interactions between nattokinase and heparin/GAGs. Glycoconjugate Journal. PMID 26412225 DOI: 10.1007/S10719-015-9620-8  0.595
2015 Wang CP, Hascall VC, Zhang F, Linhardt RJ, Abbadi A, Wang A. The responses of hyperglycemic dividing mesangial cells to heparin is mediated by the non-reducing terminal trisaccharide. The Journal of Biological Chemistry. PMID 26378235 DOI: 10.1074/Jbc.M115.677401  0.516
2015 Schaub NJ, Le Beux C, Miao J, Linhardt RJ, Alauzun JG, Laurencin D, Gilbert RJ. The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension. Plos One. 10: e0136780. PMID 26340351 DOI: 10.1371/Journal.Pone.0136780  0.678
2015 Kailemia MJ, Patel AB, Johnson DT, Li L, Linhardt RJ, Amster IJ. Differentiating chondroitin sulfate glycosaminoglycans using collision-induced dissociation; uronic acid cross-ring diagnostic fragments in a single stage of tandem mass spectrometry. European Journal of Mass Spectrometry (Chichester, England). 21: 275-85. PMID 26307707 DOI: 10.1255/Ejms.1366  0.331
2015 Ouyang Y, Zeng Y, Rong Y, Song Y, Shi L, Chen B, Yang X, Xu N, Linhardt RJ, Zhang Z. Profiling Analysis of Low Molecular Weight Heparins by Multiple Heart-Cutting Two Dimensional Chromatography with Quadruple Time-of-Flight Mass Spectrometry. Analytical Chemistry. 87: 8957-63. PMID 26222954 DOI: 10.1021/Acs.Analchem.5B02218  0.606
2015 Suflita M, Fu L, He W, Koffas M, Linhardt RJ. Heparin and related polysaccharides: synthesis using recombinant enzymes and metabolic engineering. Applied Microbiology and Biotechnology. 99: 7465-79. PMID 26219501 DOI: 10.1007/S00253-015-6821-9  0.796
2015 Zhang F, Lee KB, Linhardt RJ. SPR Biosensor Probing the Interactions between TIMP-3 and Heparin/GAGs. Biosensors. 5: 500-12. PMID 26213979 DOI: 10.3390/Bios5030500  0.639
2015 Bhaskar U, Hickey AM, Li G, Mundra RV, Zhang F, Fu L, Cai C, Ou Z, Dordick JS, Linhardt RJ. A purification process for heparin and precursor polysaccharides using the pH responsive behavior of chitosan. Biotechnology Progress. PMID 26147064 DOI: 10.1002/Btpr.2144  0.793
2015 Farrán A, Cai C, Sandoval M, Xu Y, Liu J, Hernáiz MJ, Linhardt RJ. Green solvents in carbohydrate chemistry: from raw materials to fine chemicals. Chemical Reviews. 115: 6811-53. PMID 26121409 DOI: 10.1021/Cr500719H  0.77
2015 Zhao Y, Singh A, Li L, Linhardt RJ, Xu Y, Liu J, Woods RJ, Amster IJ. Investigating changes in the gas-phase conformation of Antithrombin III upon binding of Arixtra using traveling wave ion mobility spectrometry (TWIMS). The Analyst. 140: 6980-9. PMID 26115461 DOI: 10.1039/C5An00908A  0.398
2015 Mora-Pale M, Bhan N, Masuko S, James P, Wood J, McCallum S, Linhardt RJ, Dordick JS, Koffas MA. Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol. Biotechnology and Bioengineering. PMID 26109045 DOI: 10.1002/Bit.25686  0.579
2015 Kwon SJ, Zhang F, Dordick JS, Sonstein WJ, Linhardt RJ. Detection of cerebrospinal fluid leakage by specific measurement of transferrin glycoforms. Electrophoresis. 36: 2425-32. PMID 26084971 DOI: 10.1002/Elps.201500128  0.474
2015 Jones JA, Vernacchio VR, Lachance DM, Lebovich M, Fu L, Shirke AN, Schultz VL, Cress B, Linhardt RJ, Koffas MA. ePathOptimize: A Combinatorial Approach for Transcriptional Balancing of Metabolic Pathways. Scientific Reports. 5: 11301. PMID 26062452 DOI: 10.1038/Srep11301  0.723
2015 Bhan N, Cress BF, Linhardt RJ, Koffas M. Expanding the chemical space of polyketides through structure-guided mutagenesis of Vitis vinifera stilbene synthase. Biochimie. 115: 136-43. PMID 26048582 DOI: 10.1016/J.Biochi.2015.05.019  0.707
2015 Baik JY, Dahodwala H, Oduah E, Talman L, Gemmill TR, Gasimli L, Datta P, Yang B, Li G, Zhang F, Li L, Linhardt RJ, Campbell AM, Gorfien SF, Sharfstein ST. Optimization of bioprocess conditions improves production of a CHO cell-derived, bioengineered heparin. Biotechnology Journal. 10: 1067-81. PMID 26037948 DOI: 10.1002/Biot.201400665  0.794
2015 Sun X, Li L, Overdier KH, Ammons LA, Douglas IS, Burlew CC, Zhang F, Schmidt EP, Chi L, Linhardt RJ. Analysis of Total Human Urinary Glycosaminoglycan Disaccharides by Liquid Chromatography-Tandem Mass Spectrometry. Analytical Chemistry. 87: 6220-7. PMID 26005898 DOI: 10.1021/Acs.Analchem.5B00913  0.791
2015 Hayashida A, Amano S, Gallo RL, Linhardt RJ, Liu J, Park PW. 2-O-Sulfated Domains in Syndecan-1 Heparan Sulfate Inhibit Neutrophil Cathelicidin and Promote Staphylococcus aureus Corneal Infection. The Journal of Biological Chemistry. 290: 16157-67. PMID 25931123 DOI: 10.1074/Jbc.M115.660852  0.364
2015 Yi L, Sun X, Du K, Ouyang Y, Wu C, Xu N, Linhardt RJ, Zhang Z. UP-HILIC-MS/MS to Determine the Action Pattern of Penicillium sp. Dextranase. Journal of the American Society For Mass Spectrometry. 26: 1174-85. PMID 25930093 DOI: 10.1007/S13361-015-1117-Y  0.589
2015 Li G, Li L, Xue C, Middleton D, Linhardt RJ, Avci FY. Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography-tandem mass spectrometry. Journal of Chromatography. A. 1397: 43-51. PMID 25913329 DOI: 10.1016/J.Chroma.2015.04.009  0.786
2015 Cress BF, Toparlak ÖD, Guleria S, Lebovich M, Stieglitz JT, Englaender JA, Jones JA, Linhardt RJ, Koffas MA. CRISPathBrick: Modular Combinatorial Assembly of Type II-A CRISPR Arrays for dCas9-Mediated Multiplex Transcriptional Repression in E. coli. Acs Synthetic Biology. 4: 987-1000. PMID 25822415 DOI: 10.1021/Acssynbio.5B00012  0.771
2015 Bhaskar U, Li G, Fu L, Onishi A, Suflita M, Dordick JS, Linhardt RJ. Combinatorial one-pot chemoenzymatic synthesis of heparin. Carbohydrate Polymers. 122: 399-407. PMID 25817684 DOI: 10.1016/J.Carbpol.2014.10.054  0.813
2015 Lu J, Yang H, Hao J, Wu C, Liu L, Xu N, Linhardt RJ, Zhang Z. Impact of hydrolysis conditions on the detection of mannuronic to guluronic acid ratio in alginate and its derivatives. Carbohydrate Polymers. 122: 180-8. PMID 25817657 DOI: 10.1016/J.Carbpol.2015.01.008  0.57
2015 Higashi K, Takeuchi Y, Mukuno A, Tomitori H, Miya M, Linhardt RJ, Toida T. Composition of glycosaminoglycans in elasmobranchs including several deep-sea sharks: identification of chondroitin/dermatan sulfate from the dried fins of Isurus oxyrinchus and Prionace glauca. Plos One. 10: e0120860. PMID 25803296 DOI: 10.1371/Journal.Pone.0120860  0.561
2015 Li Z, Moniz H, Wang S, Ramiah A, Zhang F, Moremen KW, Linhardt RJ, Sharp JS. High structural resolution hydroxyl radical protein footprinting reveals an extended Robo1-heparin binding interface. The Journal of Biological Chemistry. 290: 10729-40. PMID 25752613 DOI: 10.1074/Jbc.M115.648410  0.531
2015 Li G, Li L, Tian F, Zhang L, Xue C, Linhardt RJ. Glycosaminoglycanomics of cultured cells using a rapid and sensitive LC-MS/MS approach. Acs Chemical Biology. 10: 1303-10. PMID 25680304 DOI: 10.1021/Acschembio.5B00011  0.7
2015 Zhang J, Suflita M, Li G, Zhong W, Li L, Dordick JS, Linhardt RJ, Zhang F. High cell density cultivation of recombinant Escherichia coli strains expressing 2-O-sulfotransferase and C5-epimerase for the production of bioengineered heparin. Applied Biochemistry and Biotechnology. 175: 2986-95. PMID 25586487 DOI: 10.1007/S12010-014-1466-1  0.793
2015 Lamkin E, Cheng G, Calabro A, Hascall VC, Joo EJ, Li L, Linhardt RJ, Lauer ME. Heavy chain transfer by tumor necrosis factor-stimulated gene 6 to the bikunin proteoglycan. The Journal of Biological Chemistry. 290: 5156-66. PMID 25561734 DOI: 10.1074/Jbc.M114.636258  0.672
2015 Zheng Y, Monty J, Linhardt RJ. Polysaccharide-based nanocomposites and their applications. Carbohydrate Research. 405: 23-32. PMID 25498200 DOI: 10.1016/J.Carres.2014.07.016  0.545
2015 Dimitrievska S, Cai C, Weyers A, Balestrini JL, Lin T, Sundaram S, Hatachi G, Spiegel DA, Kyriakides TR, Miao J, Li G, Niklason LE, Linhardt RJ. Click-coated, heparinized, decellularized vascular grafts. Acta Biomaterialia. 13: 177-87. PMID 25463496 DOI: 10.1016/J.Actbio.2014.11.015  0.788
2015 He W, Fu L, Li G, Andrew Jones J, Linhardt RJ, Koffas M. Production of chondroitin in metabolically engineered E. coli. Metabolic Engineering. 27: 92-100. PMID 25461828 DOI: 10.1016/J.Ymben.2014.11.003  0.722
2015 Fu L, McCallum SA, Miao J, Hart C, Tudryn GJ, Zhang F, Linhardt RJ. Rapid and accurate determination of the lignin content of lignocellulosic biomass by solid-state NMR. Fuel (London, England). 141: 39-45. PMID 25404762 DOI: 10.1016/J.Fuel.2014.10.039  0.763
2015 Bhan N, Li L, Cai C, Xu P, Linhardt RJ, Koffas MA. Enzymatic formation of a resorcylic acid by creating a structure-guided single-point mutation in stilbene synthase. Protein Science : a Publication of the Protein Society. 24: 167-73. PMID 25402946 DOI: 10.1002/Pro.2600  0.545
2015 Zhang J, Suflita M, Fiaschetti CM, Li G, Li L, Zhang F, Dordick JS, Linhardt RJ. High cell density cultivation of a recombinant Escherichia coli strain expressing a 6-O-sulfotransferase for the production of bioengineered heparin. Journal of Applied Microbiology. 118: 92-8. PMID 25362996 DOI: 10.1111/Jam.12684  0.786
2015 Jasper JP, Zhang F, Poe RB, Linhardt RJ. Stable isotopic analysis of porcine, bovine, and ovine heparins. Journal of Pharmaceutical Sciences. 104: 457-63. PMID 25186630 DOI: 10.1002/Jps.24134  0.514
2015 Datta P, Yang B, Linhardt RJ, Sharfstein ST. Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells. Cytotechnology. 67: 223-35. PMID 24468831 DOI: 10.1007/S10616-013-9677-9  0.598
2015 Simmons TJ, Vera-Reveles G, González G, Gutiérrez-Hernández JM, Linhardt RJ, Navarro-Contreras H, González FJ. Bolometric properties of semiconducting and metallic single-walled carbon nanotube composite films Acs Photonics. 2: 334-340. DOI: 10.1021/Ph500285R  0.761
2015 Dickinson DM, Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparins Glycoscience: Biology and Medicine. 419-426. DOI: 10.1007/978-4-431-54841-6_42  0.599
2014 Zhang F, Liang X, Beaudet JM, Lee Y, Linhardt RJ. The Effects of Metal Ions on Heparin/Heparin Sulfate-Protein Interactions. Journal of Biomedical Technology and Research. 1. PMID 28890953  0.788
2014 Zhang F, Xie J, Linhardt RJ. Isolation and structural characterization of glycosaminoglycans from heads of red salmon (Oncorhynchus nerka). Jacobs Journal of Biotechnology and Bioengineering. 1: 002. PMID 26918243  0.571
2014 Liu Z, Zhang F, Li L, Li G, He W, Linhardt RJ. Compositional analysis and structural elucidation of glycosaminoglycans in chicken eggs. Glycoconjugate Journal. 31: 593-602. PMID 25218438 DOI: 10.1007/S10719-014-9557-3  0.775
2014 Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparan sulfate and heparin. Natural Product Reports. 31: 1676-85. PMID 25197032 DOI: 10.1039/C4Np00076E  0.438
2014 Fu L, Li L, Cai C, Li G, Zhang F, Linhardt RJ. Heparin stability by determining unsubstituted amino groups using hydrophilic interaction chromatography mass spectrometry. Analytical Biochemistry. 461: 46-8. PMID 24909446 DOI: 10.1016/J.Ab.2014.05.028  0.778
2014 Li G, Steppich J, Wang Z, Sun Y, Xue C, Linhardt RJ, Li L. Bottom-up low molecular weight heparin analysis using liquid chromatography-Fourier transform mass spectrometry for extensive characterization. Analytical Chemistry. 86: 6626-32. PMID 24905078 DOI: 10.1021/Ac501301V  0.731
2014 Aguilera JJ, Zhang F, Beaudet JM, Linhardt RJ, Colón W. Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A. Biochimie. 104: 70-80. PMID 24878279 DOI: 10.1016/J.Biochi.2014.05.007  0.777
2014 Ucakturk E, Cai C, Li L, Li G, Zhang F, Linhardt RJ. Capillary electrophoresis for total glycosaminoglycan analysis. Analytical and Bioanalytical Chemistry. 406: 4617-26. PMID 24817364 DOI: 10.1007/S00216-014-7859-8  0.782
2014 Meli L, Barbosa HS, Hickey AM, Gasimli L, Nierode G, Diogo MM, Linhardt RJ, Cabral JM, Dordick JS. Three dimensional cellular microarray platform for human neural stem cell differentiation and toxicology. Stem Cell Research. 13: 36-47. PMID 24816401 DOI: 10.1016/J.Scr.2014.04.004  0.762
2014 Zhang F, Moniz HA, Walcott B, Moremen KW, Wang L, Linhardt RJ. Probing the impact of GFP tagging on Robo1-heparin interaction. Glycoconjugate Journal. 31: 299-307. PMID 24748467 DOI: 10.1007/S10719-014-9522-1  0.516
2014 Liu L, Linhardt RJ, Zhang Z. Quantitative analysis of anions in glycosaminoglycans and application in heparin stability studies. Carbohydrate Polymers. 106: 343-50. PMID 24721088 DOI: 10.1016/J.Carbpol.2014.02.076  0.597
2014 Cai C, Dickinson DM, Li L, Masuko S, Suflita M, Schultz V, Nelson SD, Bhaskar U, Liu J, Linhardt RJ. Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides. Organic Letters. 16: 2240-3. PMID 24697306 DOI: 10.1021/Ol500738G  0.781
2014 Li G, Yang B, Li L, Zhang F, Xue C, Linhardt RJ. Analysis of 3-O-sulfo group-containing heparin tetrasaccharides in heparin by liquid chromatography-mass spectrometry. Analytical Biochemistry. 455: 3-9. PMID 24680753 DOI: 10.1016/J.Ab.2014.02.033  0.773
2014 Fu L, Zhang F, Li G, Onishi A, Bhaskar U, Sun P, Linhardt RJ. Structure and activity of a new low-molecular-weight heparin produced by enzymatic ultrafiltration. Journal of Pharmaceutical Sciences. 103: 1375-83. PMID 24634007 DOI: 10.1002/Jps.23939  0.791
2014 Sterner E, Masuko S, Li G, Li L, Green DE, Otto NJ, Xu Y, DeAngelis PL, Liu J, Dordick JS, Linhardt RJ. Fibroblast growth factor-based signaling through synthetic heparan sulfate blocks copolymers studied using high cell density three-dimensional cell printing. The Journal of Biological Chemistry. 289: 9754-65. PMID 24563485 DOI: 10.1074/Jbc.M113.546937  0.787
2014 Xu Y, Cai C, Chandarajoti K, Hsieh PH, Li L, Pham TQ, Sparkenbaugh EM, Sheng J, Key NS, Pawlinski R, Harris EN, Linhardt RJ, Liu J. Homogeneous low-molecular-weight heparins with reversible anticoagulant activity. Nature Chemical Biology. 10: 248-50. PMID 24561662 DOI: 10.1038/Nchembio.1459  0.579
2014 Schmidt EP, Li G, Li L, Fu L, Yang Y, Overdier KH, Douglas IS, Linhardt RJ. The circulating glycosaminoglycan signature of respiratory failure in critically ill adults. The Journal of Biological Chemistry. 289: 8194-202. PMID 24509853 DOI: 10.1074/Jbc.M113.539452  0.649
2014 Maeda N, Miao J, Simmons TJ, Dordick JS, Linhardt RJ. Composite polysaccharide fibers prepared by electrospinning and coating. Carbohydrate Polymers. 102: 950-5. PMID 24507368 DOI: 10.1016/J.Carbpol.2013.10.038  0.772
2014 Kwon SJ, Jeong EJ, Yoo YC, Cai C, Yang GH, Lee JC, Dordick JS, Linhardt RJ, Lee KB. High sensitivity detection of active botulinum neurotoxin by glyco-quantitative polymerase chain-reaction. Analytical Chemistry. 86: 2279-84. PMID 24506443 DOI: 10.1021/Ac500262D  0.631
2014 Volpi N, Galeotti F, Yang B, Linhardt RJ. Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone-labeled disaccharides with LC-fluorescence and LC-MS detection. Nature Protocols. 9: 541-58. PMID 24504479 DOI: 10.1038/Nprot.2014.026  0.389
2014 Joo EJ, Weyers A, Li G, Gasimli L, Li L, Choi WJ, Lee KB, Linhardt RJ. Carbohydrate-containing molecules as potential biomarkers in colon cancer. Omics : a Journal of Integrative Biology. 18: 231-41. PMID 24502776 DOI: 10.1089/Omi.2013.0128  0.774
2014 Fulcher YG, Sanganna Gari RR, Frey NC, Zhang F, Linhardt RJ, King GM, Van Doren SR. Heparinoids activate a protease, secreted by mucosa and tumors, via tethering supplemented by allostery. Acs Chemical Biology. 9: 957-66. PMID 24495220 DOI: 10.1021/Cb400898T  0.521
2014 Gasimli L, Hickey AM, Yang B, Li G, dela Rosa M, Nairn AV, Kulik MJ, Dordick JS, Moremen KW, Dalton S, Linhardt RJ. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages. Biochimica Et Biophysica Acta. 1840: 1993-2003. PMID 24412195 DOI: 10.1016/J.Bbagen.2014.01.007  0.756
2014 Cress BF, Englaender JA, He W, Kasper D, Linhardt RJ, Koffas MA. Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules. Fems Microbiology Reviews. 38: 660-97. PMID 24372337 DOI: 10.1111/1574-6976.12056  0.773
2014 Li G, Cai C, Li L, Fu L, Chang Y, Zhang F, Toida T, Xue C, Linhardt RJ. Method to detect contaminants in heparin using radical depolymerization and liquid chromatography-mass spectrometry. Analytical Chemistry. 86: 326-30. PMID 24364596 DOI: 10.1021/Ac403625A  0.794
2014 Zhang B, Xiao W, Qiu H, Zhang F, Moniz HA, Jaworski A, Condac E, Gutierrez-Sanchez G, Heiss C, Clugston RD, Azadi P, Greer JJ, Bergmann C, Moremen KW, Li D, ... Linhardt RJ, et al. Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia. The Journal of Clinical Investigation. 124: 209-21. PMID 24355925 DOI: 10.1172/Jci71090  0.478
2014 Gasimli L, Glass CA, Datta P, Yang B, Li G, Gemmill TR, Baik JY, Sharfstein ST, Esko JD, Linhardt RJ. Bioengineering murine mastocytoma cells to produce anticoagulant heparin. Glycobiology. 24: 272-80. PMID 24326668 DOI: 10.1093/Glycob/Cwt108  0.798
2014 Sterner E, Li L, Paul P, Beaudet JM, Liu J, Linhardt RJ, Dordick JS. Assays for determining heparan sulfate and heparin O-sulfotransferase activity and specificity. Analytical and Bioanalytical Chemistry. 406: 525-36. PMID 24271188 DOI: 10.1007/S00216-013-7470-4  0.802
2014 Datta P, Meli L, Li L, Migliore N, Schaefer E, Sharfstein ST, Dordick JS, Linhardt RJ. Microarray platform affords improved product analysis in mammalian cell growth studies. Biotechnology Journal. 9: 386-95. PMID 24227746 DOI: 10.1002/Biot.201300288  0.723
2014 Huang H, Zhao Y, Lv S, Zhong W, Zhang F, Linhardt RJ. Quantitation of heparosan with heparin lyase III and spectrophotometry. Analytical Biochemistry. 447: 46-8. PMID 24184357 DOI: 10.1016/J.Ab.2013.10.029  0.677
2014 Beaudet JM, Mansur L, Joo EJ, Kamhi E, Yang B, Clausen TM, Salanti A, Zhang F, Linhardt RJ. Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes. Glycoconjugate Journal. 31: 109-16. PMID 24158546 DOI: 10.1007/S10719-013-9506-6  0.769
2014 Ulaganathan T, Cherney M, Yao D, Li G, Li L, Linhardt R, Cygler M. Structural characterization of heparinase III from Bacteroides thetaiotaomicron Acta Crystallographica Section a Foundations and Advances. 70: C480-C480. DOI: 10.1107/S2053273314095199  0.644
2014 Zheng Y, Miao J, Maeda N, Frey D, Linhardt RJ, Simmons TJ. Uniform nanoparticle coating of cellulose fibers during wet electrospinning Journal of Materials Chemistry A. 2: 15029-15034. DOI: 10.1039/C4Ta03221G  0.761
2014 Walter P, Otto S, Sharf K, Riddett E, Huey Tan H, Fournier R, Zhang F, Choy F, Linhardt R, Lum J, Harmatz P. Investigation of Pharmacological Chaperones and Gluthathione in the Enhancement of NAcetylgalactosamine- 6-Sulfate Sulfatase (GALNS) in the Treatment of Mucopolysaccharidosis IVA Free Radical Biology and Medicine. 76: S95-S96. DOI: 10.1016/J.Freeradbiomed.2014.10.330  0.468
2013 Sterner E, Meli L, Kwon SJ, Dordick JS, Linhardt RJ. FGF-FGFR signaling mediated through glycosaminoglycans in microtiter plate and cell-based microarray platforms. Biochemistry. 52: 9009-19. PMID 24289246 DOI: 10.1021/Bi401284R  0.784
2013 Datta P, Li G, Yang B, Zhao X, Baik JY, Gemmill TR, Sharfstein ST, Linhardt RJ. Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site. The Journal of Biological Chemistry. 288: 37308-18. PMID 24247246 DOI: 10.1074/Jbc.M113.519033  0.8
2013 Zhang F, Moniz HA, Walcott B, Moremen KW, Linhardt RJ, Wang L. Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans. Biochimie. 95: 2345-53. PMID 23994753 DOI: 10.1016/J.Biochi.2013.08.018  0.539
2013 Chang Y, Cai C, Li L, Miao J, Ucakturk E, Li G, Ly M, Linhardt RJ. Ultrasensitive detection and quantification of acidic disaccharides using capillary electrophoresis and quantum dot-based fluorescence resonance energy transfer. Analytical Chemistry. 85: 9356-62. PMID 23985015 DOI: 10.1021/Ac402242V  0.767
2013 Zhang F, Aguilera J, Beaudet JM, Xie Q, Lerch TF, Davulcu O, Colón W, Chapman MS, Linhardt RJ. Characterization of interactions between heparin/glycosaminoglycan and adeno-associated virus. Biochemistry. 52: 6275-85. PMID 23952613 DOI: 10.1021/Bi4008676  0.789
2013 Cai C, Li L, Harvey C, Liu J, Linhardt RJ. Towards the chemoenzymatic synthesis of heparan sulfate oligosaccharides: Oxidative cleavage of p-nitrophenyl group with ceric ammonium salts. Tetrahedron Letters. 54: 4471-4474. PMID 23929984 DOI: 10.1016/J.Tetlet.2013.06.044  0.549
2013 Wang W, Englaender JA, Xu P, Mehta KK, Suwan J, Dordick JS, Zhang F, Yuan Q, Linhardt RJ, Koffas M. Expression of low endotoxin 3-O-sulfotransferase in Bacillus subtilis and Bacillus megaterium. Applied Biochemistry and Biotechnology. 171: 954-62. PMID 23912211 DOI: 10.1007/S12010-013-0415-8  0.773
2013 Nicastri MC, Xega K, Li L, Xie J, Wang C, Linhardt RJ, Reitter JN, Mills KV. Internal disulfide bond acts as a switch for intein activity. Biochemistry. 52: 5920-7. PMID 23906287 DOI: 10.1021/Bi400736C  0.441
2013 Nolan K, Kattamuri C, Luedeke DM, Deng X, Jagpal A, Zhang F, Linhardt RJ, Kenny AP, Zorn AM, Thompson TB. Structure of protein related to Dan and Cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure (London, England : 1993). 21: 1417-29. PMID 23850456 DOI: 10.1016/J.Str.2013.06.005  0.514
2013 Xiong J, Bhaskar U, Li G, Fu L, Li L, Zhang F, Dordick JS, Linhardt RJ. Immobilized enzymes to convert N-sulfo, N-acetyl heparosan to a critical intermediate in the production of bioengineered heparin. Journal of Biotechnology. 167: 241-7. PMID 23835156 DOI: 10.1016/J.Jbiotec.2013.06.018  0.791
2013 Zhao X, Yang B, Li L, Zhang F, Linhardt RJ. On-line separation and characterization of hyaluronan oligosaccharides derived from radical depolymerization. Carbohydrate Polymers. 96: 503-9. PMID 23768593 DOI: 10.1016/J.Carbpol.2013.04.009  0.617
2013 Li G, Masuko S, Green DE, Xu Y, Li L, Zhang F, Xue C, Liu J, Deangelis PL, Linhardt RJ. N-sulfotestosteronan, a novel substrate for heparan sulfate 6-o-sulfotransferases and its analysis by oxidative degradation. Biopolymers. 99: 675-85. PMID 23606289 DOI: 10.1002/Bip.22263  0.794
2013 Weyers A, Yang B, Park JH, Kim YS, Kim SM, Lee SE, Zhang F, Lee KB, Linhardt RJ. Microanalysis of stomach cancer glycosaminoglycans. Glycoconjugate Journal. 30: 701-7. PMID 23604988 DOI: 10.1007/S10719-013-9476-8  0.778
2013 Hickey AM, Bhaskar U, Linhardt RJ, Dordick JS. Effect of eliminase gene (elmA) deletion on heparosan production and shedding in Escherichia coli K5. Journal of Biotechnology. 165: 175-7. PMID 23583654 DOI: 10.1016/J.Jbiotec.2013.03.018  0.774
2013 Kamhi E, Joo EJ, Dordick JS, Linhardt RJ. Glycosaminoglycans in infectious disease. Biological Reviews of the Cambridge Philosophical Society. 88: 928-43. PMID 23551941 DOI: 10.1111/Brv.12034  0.778
2013 Fu L, Li G, Yang B, Onishi A, Li L, Sun P, Zhang F, Linhardt RJ. Structural characterization of pharmaceutical heparins prepared from different animal tissues. Journal of Pharmaceutical Sciences. 102: 1447-57. PMID 23526651 DOI: 10.1002/Jps.23501  0.801
2013 Cai C, Edgar K, Liu J, Linhardt RJ. Preparation and application of a 'clickable' acceptor for enzymatic synthesis of heparin oligosaccharides. Carbohydrate Research. 372: 30-4. PMID 23524108 DOI: 10.1016/J.Carres.2013.02.010  0.575
2013 Cress BF, Greene ZR, Linhardt RJ, Koffas MA. Draft Genome Sequence of Escherichia coli Strain ATCC 23506 (Serovar O10:K5:H4). Genome Announcements. 1: e0004913. PMID 23516192 DOI: 10.1128/genomeA.00049-13  0.669
2013 Cress BF, Linhardt RJ, Koffas MA. Draft Genome Sequence of Escherichia coli Strain Nissle 1917 (Serovar O6:K5:H1). Genome Announcements. 1: e0004713. PMID 23516190 DOI: 10.1128/Genomea.00047-13  0.687
2013 Cress BF, Greene ZR, Linhardt RJ, Koffas MA. Draft Genome Sequence of Escherichia coli Strain ATCC 23502 (Serovar O5:K4:H4). Genome Announcements. 1: e0004613. PMID 23516189 DOI: 10.1128/Genomea.00046-13  0.695
2013 DeAngelis PL, Liu J, Linhardt RJ. Chemoenzymatic synthesis of glycosaminoglycans: re-creating, re-modeling and re-designing nature's longest or most complex carbohydrate chains. Glycobiology. 23: 764-77. PMID 23481097 DOI: 10.1093/Glycob/Cwt016  0.398
2013 Zhang F, Walcott B, Zhou D, Gustchina A, Lasanajak Y, Smith DF, Ferreira RS, Correia MT, Paiva PM, Bovin NV, Wlodawer A, Oliva ML, Linhardt RJ. Structural studies of the interaction of Crataeva tapia bark protein with heparin and other glycosaminoglycans. Biochemistry. 52: 2148-56. PMID 23448527 DOI: 10.1021/Bi400077B  0.559
2013 Kailemia MJ, Li L, Xu Y, Liu J, Linhardt RJ, Amster IJ. Structurally informative tandem mass spectrometry of highly sulfated natural and chemoenzymatically synthesized heparin and heparan sulfate glycosaminoglycans. Molecular & Cellular Proteomics : McP. 12: 979-90. PMID 23429520 DOI: 10.1074/Mcp.M112.026880  0.415
2013 Zhao X, Yang B, Solakyildirim K, Solakylidirim K, Joo EJ, Toida T, Higashi K, Linhardt RJ, Li L. Sequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain. The Journal of Biological Chemistry. 288: 9226-37. PMID 23423381 DOI: 10.1074/Jbc.M112.437236  0.785
2013 Weyers A, Yang B, Solakyildirim K, Yee V, Li L, Zhang F, Linhardt RJ. Isolation of bovine corneal keratan sulfate and its growth factor and morphogen binding Febs Journal. 280: 2285-2293. PMID 23402351 DOI: 10.1111/Febs.12165  0.785
2013 Weyers A, Linhardt RJ. Neoproteoglycans in tissue engineering Febs Journal. 280: 2511-2522. PMID 23399318 DOI: 10.1111/Febs.12187  0.753
2013 Chang Y, Yang B, Weyers A, Linhardt RJ. Capillary electrophoresis for the analysis of glycosaminoglycan-derived disaccharides. Methods in Molecular Biology (Clifton, N.J.). 984: 67-77. PMID 23386338 DOI: 10.1007/978-1-62703-296-4_7  0.779
2013 Kotlo K, Bhattacharyya S, Yang B, Feferman L, Tejaskumar S, Linhardt R, Danziger R, Tobacman JK. Impact of salt exposure on N-acetylgalactosamine-4-sulfatase (arylsulfatase B) activity, glycosaminoglycans, kininogen, and bradykinin. Glycoconjugate Journal. 30: 667-76. PMID 23385884 DOI: 10.1007/S10719-013-9468-8  0.388
2013 Zhou X, Li L, Linhardt RJ, Liu J. Neutralizing the anticoagulant activity of ultra-low-molecular-weight heparins using N-acetylglucosamine 6-sulfatase Febs Journal. 280: 2523-2532. PMID 23374371 DOI: 10.1111/Febs.12169  0.394
2013 Datta P, Linhardt RJ, Sharfstein ST. An 'omics approach towards CHO cell engineering. Biotechnology and Bioengineering. 110: 1255-71. PMID 23322664 DOI: 10.1002/Bit.24841  0.51
2013 Restaino OF, Bhaskar U, Paul P, Li L, De Rosa M, Dordick JS, Linhardt RJ. High cell density cultivation of a recombinant E. coli strain expressing a key enzyme in bioengineered heparin production. Applied Microbiology and Biotechnology. 97: 3893-900. PMID 23318839 DOI: 10.1007/S00253-012-4682-Z  0.79
2013 Zhao X, Yang B, Linkens K, Datta P, Onishi A, Zhang F, Linhardt RJ. Microscale separation of heparosan, heparan sulfate, and heparin. Analytical Biochemistry. 434: 215-7. PMID 23262074 DOI: 10.1016/J.Ab.2012.12.009  0.791
2013 Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, Liang X, Su J, Baker JE, Linhardt RJ, Volkman BF. Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus. The Journal of Biological Chemistry. 288: 737-46. PMID 23148226 DOI: 10.1074/Jbc.M112.394064  0.753
2013 Gasimli L, Stansfield HE, Nairn AV, Liu H, Paluh JL, Yang B, Dordick JS, Moremen KW, Linhardt RJ. Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells Glycoconjugate Journal. 30: 497-510. PMID 23053635 DOI: 10.1007/S10719-012-9450-X  0.788
2013 Donald A, Taylor T, Miao J, Linhardt R, Jackson D, Mendenhall J. High Affinity Membranes for Cellulase Enzyme Detection in Subterranean Termites Mrs Proceedings. 1569: 245-249. DOI: 10.1557/Opl.2013.1079  0.705
2013 Zhao X, Yang B, Solakyildirim K, Joo EJ, Toida T, Higashi K, Linhardt RJ, Li L. Erratum: Sequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain (The Journal of Biological Chemistry (2013) 288 (9226-9237)) Journal of Biological Chemistry. 288. DOI: 10.1074/Jbc.A112.437236  0.766
2013 Simmons TJ, Maeda N, Miyauchi M, Miao J, Hashim DP, Ajayan PM, Dordick JS, Linhardt RJ. Effect of a variety of carbon nanotubes on the iodine-iodide redox pair Carbon. 62: 177-181. DOI: 10.1016/J.Carbon.2013.06.009  0.761
2013 Simmons TJ, Maeda N, Miao J, Bravo-Sanchez M, Dordick JS, Linhardt RJ. Self-assembly of carbon nanotube films from room temperature ionic liquids Carbon. 58: 226-231. DOI: 10.1016/J.Carbon.2013.02.062  0.763
2013 Webster M, Miao J, Lynch B, Green D, Jones-Sawyer R, Linhardt RJ, Mendenhall J. Tunable thermo-responsive poly(N-vinylcaprolactam) cellulose nanofibers: Synthesis, characterization, and fabrication Macromolecular Materials and Engineering. 298: 447-453. DOI: 10.1002/Mame.201200081  0.695
2013 Li G, Masuko S, Green DE, Xu Y, Li L, Zhang F, Xue C, Liu J, Deangelis PL, Linhardt RJ. N-sulfotestosteronan, A novel substrate for heparan sulfate 6-O-sulfotransferases and its analysis by oxidative degradation Biopolymers. 99: 675-685. DOI: 10.1002/bip.22263  0.696
2013 Bhan N, Mora-Pale M, Koffas MAG, Linhardt RJ, Dordick JS, Masuko S. Generation of resveratrol analogues by enzymatic oligomerization and protein engineering Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 512.  0.491
2013 Mora-Pale M, Bhan N, Masuko S, Linhardt RJ, Koffas MAG, Dordick JS. Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from the enzymatic oligomerization of resveratrol mediated by soybean peroxidase Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 345.  0.499
2012 Zhao X, Yang B, Datta P, Gasmili L, Zhang F, Linhardt RJ. Cell-Based Microscale Isolation of Glycoaminoglycans for Glycomics Study. Journal of Carbohydrate Chemistry. 31: 420-435. PMID 24068855 DOI: 10.1080/07328303.2012.658126  0.712
2012 Suwan J, Torelli A, Onishi A, Dordick JS, Linhardt RJ. Addressing endotoxin issues in bioengineered heparin. Biotechnology and Applied Biochemistry. 59: 420-8. PMID 23586950 DOI: 10.1002/Bab.1042  0.786
2012 Gasimli L, Linhardt RJ, Dordick JS. Proteoglycans in stem cells. Biotechnology and Applied Biochemistry. 59: 65-76. PMID 23586787 DOI: 10.1002/Bab.1002  0.305
2012 Wang Z, Zhang F, Dordick JS, Linhardt RJ. Molecular Mass Characterization of Glycosaminoglycans with Different Degrees of Sulfation in Bioengineered Heparin Process by Size Exclusion Chromatography. Current Analytical Chemistry. 8: 506-511. PMID 23258975 DOI: 10.2174/157341112803216753  0.599
2012 Kwon SJ, Lee KB, Solakyildirim K, Masuko S, Ly M, Zhang F, Li L, Dordick JS, Linhardt RJ. Signal amplification by glyco-qPCR for ultrasensitive detection of carbohydrates: applications in glycobiology. Angewandte Chemie (International Ed. in English). 51: 11800-4. PMID 23073897 DOI: 10.1002/Anie.201205112  0.77
2012 Meli L, Jordan ET, Clark DS, Linhardt RJ, Dordick JS. Influence of a three-dimensional, microarray environment on human cell culture in drug screening systems. Biomaterials. 33: 9087-96. PMID 22998815 DOI: 10.1016/J.Biomaterials.2012.08.065  0.659
2012 Li L, Zhang F, Zaia J, Linhardt RJ. Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS. Analytical Chemistry. 84: 8822-9. PMID 22985071 DOI: 10.1021/Ac302232C  0.532
2012 Leach FE, Ly M, Laremore TN, Wolff JJ, Perlow J, Linhardt RJ, Amster IJ. Hexuronic acid stereochemistry determination in chondroitin sulfate glycosaminoglycan oligosaccharides by electron detachment dissociation. Journal of the American Society For Mass Spectrometry. 23: 1488-97. PMID 22825742 DOI: 10.1007/S13361-012-0428-5  0.785
2012 Simmons TJ, Hashim DP, Zhan X, Bravo-Sanchez M, Hahm MG, López-Luna E, Linhardt RJ, Ajayan PM, Navarro-Contreras H, Vidal MA. Functionalization of nitrogen-doped carbon nanotubes with gallium to form Ga-CN(x)-multi-wall carbon nanotube hybrid materials. Nanotechnology. 23: 325601. PMID 22825368 DOI: 10.1088/0957-4484/23/32/325601  0.758
2012 Zhang F, Beaudet JM, Luedeke DM, Walker RG, Thompson TB, Linhardt RJ. Analysis of the interaction between heparin and follistatin and heparin and follistatin-ligand complexes using surface plasmon resonance. Biochemistry. 51: 6797-803. PMID 22809401 DOI: 10.1021/Bi300804G  0.792
2012 Miao J, Miyauchi M, Dordick JS, Linhardt RJ. Preparation and characterization of electrospun core sheath nanofibers from multi-walled carbon nanotubes and poly(vinyl pyrrolidone). Journal of Nanoscience and Nanotechnology. 12: 2387-93. PMID 22755063 DOI: 10.1166/Jnn.2012.5710  0.693
2012 Volpi N, Maccari F, Suwan J, Linhardt RJ. Electrophoresis for the analysis of heparin purity and quality. Electrophoresis. 33: 1531-7. PMID 22736353 DOI: 10.1002/Elps.201100479  0.799
2012 Kailemia MJ, Li L, Ly M, Linhardt RJ, Amster IJ. Complete mass spectral characterization of a synthetic ultralow-molecular-weight heparin using collision-induced dissociation. Analytical Chemistry. 84: 5475-8. PMID 22715938 DOI: 10.1021/Ac3015824  0.597
2012 Baik JY, Wang CL, Yang B, Linhardt RJ, Sharfstein S. Toward a bioengineered heparin: challenges and strategies for metabolic engineering of mammalian cells. Bioengineered. 3: 227-31. PMID 22714556 DOI: 10.4161/Bioe.20902  0.76
2012 Chang Y, Yang B, Zhao X, Linhardt RJ. Analysis of glycosaminoglycan-derived disaccharides by capillary electrophoresis using laser-induced fluorescence detection. Analytical Biochemistry. 427: 91-8. PMID 22609076 DOI: 10.1016/J.Ab.2012.05.004  0.667
2012 Paul P, Suwan J, Liu J, Dordick JS, Linhardt RJ. Recent advances in sulfotransferase enzyme activity assays. Analytical and Bioanalytical Chemistry. 403: 1491-500. PMID 22526635 DOI: 10.1007/S00216-012-5944-4  0.778
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