William R. Bishai - Publications

2004 Infectious Diseases Johns Hopkins University, Baltimore, MD 
molecular pathogenesis of tuberculosis

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bhattacharya B, Xiao S, Chatterjee S, Urbanowski ME, Ordonez AA, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor JH, Ivanov AR, Yan BS, Kobzik L, ... ... Bishai WR, et al. The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. The Journal of Clinical Investigation. PMID 33301427 DOI: 10.1172/JCI130319  0.56
2020 Urbanowski ME, Ordonez AA, Ruiz-Bedoya CA, Jain SK, Bishai WR. Cavitary tuberculosis: the gateway of disease transmission. The Lancet. Infectious Diseases. 20: e117-e128. PMID 32482293 DOI: 10.1016/S1473-3099(20)30148-1  0.56
2019 Xiao S, Guo H, Weiner WS, Maddox C, Mao C, Gunosewoyo H, Pelly S, White EL, Rasmussen L, Schoenen FJ, Aubé J, Bishai WR, Lun S. Revisiting the β-lactams for tuberculosis therapy: a compound-compound synthetic lethality approach. Antimicrobial Agents and Chemotherapy. PMID 31427291 DOI: 10.1128/AAC.01319-19  0.48
2019 Kumar P, Kumar A, Parveen S, Murphy JR, Bishai W. Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy. Immunotherapy. PMID 31361167 DOI: 10.2217/imt-2019-0060  0.6
2019 Parveen S, Bishai WR, Murphy JR. : Diphtheria Toxin, the Operon, and Its Regulation by Fe2 Activation of apo-DtxR. Microbiology Spectrum. 7. PMID 31267892 DOI: 10.1128/microbiolspec.GPP3-0063-2019  0.6
2019 Cheung LS, Fu J, Kumar P, Kumar A, Urbanowski ME, Ihms EA, Parveen S, Bullen CK, Patrick GJ, Harrison R, Murphy JR, Pardoll DM, Bishai WR. Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718426 DOI: 10.1073/pnas.1815087116  0.6
2018 Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, Kübler A, Bishai WR, Elkington PT, Jain SK. Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology. The Journal of Infectious Diseases. PMID 29920600 DOI: 10.1093/infdis/jiy373  0.56
2018 Rifat D, Prideaux B, Savic RM, Urbanowski ME, Parsons TL, Luna B, Marzinke MA, Ordonez AA, DeMarco VP, Jain SK, Dartois V, Bishai WR, Dooley KE. Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data. Science Translational Medicine. 10. PMID 29618565 DOI: 10.1126/scitranslmed.aai7786  0.56
2017 Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR. Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. The Journal of Infectious Diseases. 215: 1883-1887. PMID 28863467 DOI: 10.1093/infdis/jix208  0.6
2017 Dey RJ, Dey B, Zheng Y, Cheung LS, Zhou J, Sayre D, Kumar P, Guo H, Lamichhane G, Sintim HO, Bishai WR. Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase. Nature Chemical Biology. 13: 210-217. PMID 28106876 DOI: 10.1038/nchembio.2254  1
2016 Pelly S, Winglee K, Xia F, Stevens RL, Bishai WR, Lamichhane G. REMap: Operon map of M. tuberculosis based on RNA sequence data. Tuberculosis (Edinburgh, Scotland). 99: 70-80. PMID 27450008 DOI: 10.1016/j.tube.2016.04.010  1
2016 Winglee K, Manson McGuire A, Maiga M, Abeel T, Shea T, Desjardins CA, Diarra B, Baya B, Sanogo M, Diallo S, Earl AM, Bishai WR. Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction. Plos Neglected Tropical Diseases. 10: e0004332. PMID 26751217 DOI: 10.1371/journal.pntd.0004332  0.68
2016 Pelly S, Winglee K, Xia F, Stevens RL, Bishai WR, Lamichhane G. REMap: Operon map of M. tuberculosis based on RNA sequence data Tuberculosis. 99: 70-80. DOI: 10.1016/j.tube.2016.04.010  0.68
2015 Maiga M, Ahidjo BA, Maiga MC, Cheung L, Pelly S, Lun S, Bougoudogo F, Bishai WR. Erratum to "Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis" [EBioMedicine 2 (8), August 2015, 868-873]. Ebiomedicine. 2: 1834. PMID 26870809 DOI: 10.1016/j.ebiom.2015.10.019  0.48
2015 Maiga M, Ahidjo BA, Maiga MC, Cheung L, Pelly S, Lun S, Bougoudogo F, Bishai WR. Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis. Ebiomedicine. 2: 866-71. PMID 26425693 DOI: 10.1016/j.ebiom.2015.07.014  0.48
2015 Cohen KA, Abeel T, Manson McGuire A, Desjardins CA, Munsamy V, Shea TP, Walker BJ, Bantubani N, Almeida DV, Alvarado L, Chapman SB, Mvelase NR, Duffy EY, Fitzgerald MG, Govender P, ... ... Bishai WR, et al. Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal. Plos Medicine. 12: e1001880. PMID 26418737 DOI: 10.1371/journal.pmed.1001880  0.68
2015 Kubler A, Larsson C, Luna B, Andrade BB, Amaral EP, Urbanowski M, Orandle M, Bock K, Ammerman NC, Cheung LS, Winglee K, Halushka M, Park JK, Sher A, Friedland JS, ... ... Bishai WR, et al. Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis. The Journal of Infectious Diseases. PMID 26416658 DOI: 10.1093/infdis/jiv458  0.68
2015 Srikrishna G, Gupta S, Dooley KE, Bishai WR. Can the addition of verapamil to bedaquiline-containing regimens improve tuberculosis treatment outcomes? A novel approach to optimizing TB treatment. Future Microbiology. 10: 1257-60. PMID 26226503 DOI: 10.2217/FMB.15.56  0.68
2015 Xu Z, Bagci U, Mansoor A, Kramer-Marek G, Luna B, Kubler A, Dey B, Foster B, Papadakis GZ, Camp JV, Jonsson CB, Bishai WR, Jain S, Udupa JK, Mollura DJ. Computer-aided pulmonary image analysis in small animal models. Medical Physics. 42: 3896. PMID 26133591 DOI: 10.1118/1.4921618  0.68
2015 Sullivan ZA, Wong EB, Ndung'u T, Kasprowicz VO, Bishai WR. Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV. Ebiomedicine. 2: 334-340. PMID 26114158 DOI: 10.1016/j.ebiom.2015.03.005  0.68
2015 Pan SJ, Tapley A, Adamson J, Little T, Urbanowski M, Cohen K, Pym A, Almeida D, Dorasamy A, Layre E, Young DC, Singh R, Patel VB, Wallengren K, Ndung'u T, ... ... Bishai W, et al. Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules. The Journal of Infectious Diseases. PMID 26014799 DOI: 10.1093/infdis/jiv312  0.68
2015 Alyahya SA, Nolan ST, Smith CM, Bishai WR, Sadoff J, Lamichhane G. Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment. Plos One. 10: e0127907. PMID 25996375 DOI: 10.1371/journal.pone.0127907  1
2015 Young DC, Layre E, Pan SJ, Tapley A, Adamson J, Seshadri C, Wu Z, Buter J, Minnaard AJ, Coscolla M, Gagneux S, Copin R, Ernst JD, Bishai WR, Snider BB, et al. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection. Chemistry & Biology. 22: 516-26. PMID 25910243 DOI: 10.1016/j.chembiol.2015.03.015  0.68
2015 Rahman MA, Sobia P, Dwivedi VP, Bhawsar A, Singh DK, Sharma P, Moodley P, Van Kaer L, Bishai WR, Das G. Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis. The Journal of Biological Chemistry. 290: 14407-17. PMID 25847237 DOI: 10.1074/jbc.M115.653600  0.68
2015 Silva JR, Bishai WR, Govender T, Lamichhane G, Maguire GE, Kruger HG, Lameira J, Alves CN. Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 25762064 DOI: 10.1080/07391102.2015.1029000  0.68
2015 Sharma PK, Wong EB, Napier RJ, Bishai WR, Ndung'u T, Kasprowicz VO, Lewinsohn DA, Lewinsohn DM, Gold MC. High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells. Immunology. 145: 443-53. PMID 25752900 DOI: 10.1111/imm.12461  0.68
2015 Dey B, Dey RJ, Cheung LS, Pokkali S, Guo H, Lee JH, Bishai WR. A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis. Nature Medicine. 21: 401-6. PMID 25730264 DOI: 10.1038/nm.3813  0.68
2015 Hiruy H, Rogers Z, Mbowane C, Adamson J, Ngotho L, Karim F, Gumbo T, Bishai W, Jeena P. Subtherapeutic concentrations of first-line anti-TB drugs in South African children treated according to current guidelines: the PHATISA study. The Journal of Antimicrobial Chemotherapy. 70: 1115-23. PMID 25505005 DOI: 10.1093/jac/dku478  0.68
2015 Gupta S, Tyagi S, Bishai WR. Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model. Antimicrobial Agents and Chemotherapy. 59: 673-6. PMID 25331694 DOI: 10.1128/AAC.04019-14  0.52
2015 Kübler A, Luna B, Larsson C, Ammerman NC, Andrade BB, Orandle M, Bock KW, Xu Z, Bagci U, Molura DJ, Marshall J, Burns J, Winglee K, Ahidjo BA, Cheung LS, ... ... Bishai WR, et al. Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation. The Journal of Pathology. 235: 431-44. PMID 25186281 DOI: 10.1002/path.4432  0.68
2015 Luna B, Kubler A, Larsson C, Foster B, Bagci U, Mollura DJ, Jain SK, Bishai WR. In vivo prediction of tuberculosis-associated cavity formation in rabbits. The Journal of Infectious Diseases. 211: 481-5. PMID 25117755 DOI: 10.1093/infdis/jiu449  0.68
2015 Winglee K, Lun S, Pieroni M, Kozikowski A, Bishai W. Mutation of Rv2887, a marR-Like gene, confers mycobacterium tuberculosis resistance to an imidazopyridine-based agent Antimicrobial Agents and Chemotherapy. 59: 6873-6881. DOI: 10.1128/AAC.01341-15  0.68
2015 Cohen KA, Abeel T, McGuire AM, Desjardins CA, Munsamy V, Shea TP, Walker BJ, Bantubani N, Almeida DV, Alvarado L, Chapman S, Mvelase NR, Duffy EY, Fitzgerald MG, Govender P, ... ... Bishai WR, et al. Evolution of extensively drug-resistant tuberculosis over four decades revealed by whole genome sequencing of Mycobacterium tuberculosis from KwaZulu-Natal, South Africa International Journal of Mycobacteriology. DOI: 10.1016/j.ijmyco.2014.11.028  0.68
2014 Cohen KA, Bishai WR, Pym AS. Molecular Basis of Drug Resistance in Mycobacterium tuberculosis. Microbiology Spectrum. 2. PMID 26103975 DOI: 10.1128/microbiolspec.MGM2-0036-2013  0.68
2014 Almeida DV, Tyagi S, Li S, Wallengren K, Pym AS, Ammerman NC, Bishai WR, Grosset JH. Revisiting Anti-tuberculosis Activity of Pyrazinamide in Mice. Mycobacterial Diseases : Tuberculosis & Leprosy. 4: 145. PMID 25525563 DOI: 10.4172/2161-1068.1000145  0.52
2014 Dey B, Bishai WR. Crosstalk between Mycobacterium tuberculosis and the host cell. Seminars in Immunology. 26: 486-96. PMID 25303934 DOI: 10.1016/j.smim.2014.09.002  0.68
2014 Choi SW, Maiga M, Maiga MC, Atudorei V, Sharp ZD, Bishai WR, Timmins GS. Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test. Nature Communications. 5: 4989. PMID 25247851 DOI: 10.1038/ncomms5989  0.68
2014 Lun S, Miranda D, Kubler A, Guo H, Maiga MC, Winglee K, Pelly S, Bishai WR. Synthetic lethality reveals mechanisms of Mycobacterium tuberculosis resistance to β-lactams. Mbio. 5: e01767-14. PMID 25227469 DOI: 10.1128/mBio.01767-14  0.48
2014 Stec J, Vilchèze C, Lun S, Perryman AL, Wang X, Freundlich JS, Bishai W, Jacobs WR, Kozikowski AP. Biological evaluation of potent triclosan-derived inhibitors of the enoyl-acyl carrier protein reductase InhA in drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. Chemmedchem. 9: 2528-37. PMID 25165007 DOI: 10.1002/cmdc.201402255  0.68
2014 Maiga M, Choi SW, Atudorei V, Maiga MC, Sharp ZD, Bishai WR, Timmins GS. In vitro and in vivo studies of a rapid and selective breath test for tuberculosis based upon mycobacterial CO dehydrogenase. Mbio. 5: e00990. PMID 24736224 DOI: 10.1128/mBio.00990-14  0.68
2014 Bhattacharya D, Dwivedi VP, Maiga M, Maiga M, Van Kaer L, Bishai WR, Das G. Small molecule-directed immunotherapy against recurrent infection by Mycobacterium tuberculosis. The Journal of Biological Chemistry. 289: 16508-15. PMID 24711459 DOI: 10.1074/jbc.M114.558098  0.68
2014 Choudhary E, Bishai W, Agarwal N. Expression of a subset of heat stress induced genes of mycobacterium tuberculosis is regulated by 3′,5′-cyclic AMP Plos One. 9. PMID 24587015 DOI: 10.1371/journal.pone.0089759  0.68
2014 Schoonmaker MK, Bishai WR, Lamichhane G. Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams. Journal of Bacteriology. 196: 1394-402. PMID 24464457 DOI: 10.1128/JB.01396-13  1
2014 Drain PK, Hyle EP, Noubary F, Freedberg KA, Wilson D, Bishai WR, Rodriguez W, Bassett IV. Diagnostic point-of-care tests in resource-limited settings. The Lancet. Infectious Diseases. 14: 239-49. PMID 24332389 DOI: 10.1016/S1473-3099(13)70250-0  0.68
2014 Ordonez AA, Maiga M, Gupta S, Weinstein EA, Bishai WR, Jain SK. Novel adjunctive therapies for the treatment of tuberculosis. Current Molecular Medicine. 14: 385-95. PMID 24236454 DOI: 10.2174/1566524013666131118112431  0.56
2014 Foster B, Bagci U, Ziyue Xu, Dey B, Luna B, Bishai W, Jain S, Mollura DJ. Segmentation of PET images for computer-aided functional quantification of tuberculosis in small animal models. Ieee Transactions On Bio-Medical Engineering. 61: 711-24. PMID 24235292 DOI: 10.1109/TBME.2013.2288258  0.68
2014 Gupta S, Cohen KA, Winglee K, Maiga M, Diarra B, Bishai WR. Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 574-6. PMID 24126586 DOI: 10.1128/AAC.01462-13  0.68
2013 Wong EB, Akilimali NA, Govender P, Sullivan ZA, Cosgrove C, Pillay M, Lewinsohn DM, Bishai WR, Walker BD, Ndung'u T, Klenerman P, Kasprowicz VO. Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection. Plos One. 8: e83474. PMID 24391773 DOI: 10.1371/journal.pone.0083474  0.68
2013 Lun S, Guo H, Onajole OK, Pieroni M, Gunosewoyo H, Chen G, Tipparaju SK, Ammerman NC, Kozikowski AP, Bishai WR. Indoleamides are active against drug-resistant mycobacterium tuberculosis Nature Communications. 4. PMID 24352433 DOI: 10.1038/ncomms3907  0.68
2013 Xu Z, Bagci U, Kubler A, Luna B, Jain S, Bishai WR, Mollura DJ. Computer-aided detection and quantification of cavitary tuberculosis from CT scans. Medical Physics. 40: 113701. PMID 24320475 DOI: 10.1118/1.4824979  0.68
2013 Seddon J, Kasprowicz V, Walker NF, Yuen HM, Sunpath H, Tezera L, Meintjes G, Wilkinson RJ, Bishai WR, Friedland JS, Elkington PT. Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis. The Journal of Infectious Diseases. 208: 1571-9. PMID 23922364 DOI: 10.1093/infdis/jit343  0.68
2013 Bagci U, Foster B, Miller-Jaster K, Luna B, Dey B, Bishai WR, Jonsson CB, Jain S, Mollura DJ. A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging. Ejnmmi Research. 3: 55. PMID 23879987 DOI: 10.1186/2191-219X-3-55  0.68
2013 Lun S, Guo H, Adamson J, Cisar JS, Davis TD, Chavadi SS, Warren JD, Quadri LE, Tan DS, Bishai WR. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrobial Agents and Chemotherapy. 57: 5138-40. PMID 23856770 DOI: 10.1128/AAC.00918-13  0.68
2013 Grosset JH, Tyagi S, Almeida DV, Converse PJ, Li SY, Ammerman NC, Bishai WR, Enarson D, Trébucq A. Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice. American Journal of Respiratory and Critical Care Medicine. 188: 608-12. PMID 23822735 DOI: 10.1164/rccm.201304-0753OC  0.68
2013 Gupta S, Tyagi S, Almeida DV, Maiga MC, Ammerman NC, Bishai WR. Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor. American Journal of Respiratory and Critical Care Medicine. 188: 600-7. PMID 23805786 DOI: 10.1164/rccm.201304-0650OC  0.68
2013 Bassett IM, Lun S, Bishai WR, Guo H, Kirman JR, Altaf M, O'Toole RF. Detection of inhibitors of phenotypically drug-tolerant Mycobacterium tuberculosis using an in vitro bactericidal screen. Journal of Microbiology (Seoul, Korea). 51: 651-8. PMID 23800952 DOI: 10.1007/s12275-013-3099-4  0.68
2013 Maiga M, Ammerman NC, Maiga MC, Tounkara A, Siddiqui S, Polis M, Murphy R, Bishai WR. Adjuvant host-directed therapy with types 3 and 5 but not type 4 phosphodiesterase inhibitors shortens the duration of tuberculosis treatment. The Journal of Infectious Diseases. 208: 512-9. PMID 23641020 DOI: 10.1093/infdis/jit187  0.68
2013 Onajole OK, Pieroni M, Tipparaju SK, Lun S, Stec J, Chen G, Gunosewoyo H, Guo H, Ammerman NC, Bishai WR, Kozikowski AP. Preliminary structure - Activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains Journal of Medicinal Chemistry. 56: 4093-4103. PMID 23611124 DOI: 10.1021/jm4003878  0.68
2013 Bishai W, Sullivan Z, Bloom BR, Andersen P. Bettering BCG: a tough task for a TB vaccine? Nature Medicine. 19: 410-1. PMID 23558628 DOI: 10.1038/nm.3153  0.68
2013 Singh Y, Kaul V, Mehra A, Chatterjee S, Tousif S, Dwivedi VP, Suar M, Van Kaer L, Bishai WR, Das G. Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity. The Journal of Biological Chemistry. 288: 5056-61. PMID 23233675 DOI: 10.1074/jbc.C112.439778  0.68
2013 Foster B, Bagci U, Luna B, Dey B, Bishai W, Jain S, Xu Z, Mollura DJ. Robust segmentation and accurate target definition for positron emission tomography images using Affinity Propagation Proceedings - International Symposium On Biomedical Imaging. 1461-1464. DOI: 10.1109/ISBI.2013.6556810  0.68
2012 Erdemli SB, Gupta R, Bishai WR, Lamichhane G, Amzel LM, Bianchet MA. Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2. Structure (London, England : 1993). 20: 2103-15. PMID 23103390 DOI: 10.1016/j.str.2012.09.016  0.68
2012 Parthasarathy G, Lun S, Guo H, Ammerman NC, Geiman DE, Bishai WR. Rv2190c, an NlpC/P60 family protein, is required for full virulence of Mycobacterium tuberculosis. Plos One. 7: e43429. PMID 22952680 DOI: 10.1371/journal.pone.0043429  0.68
2012 Grosset J, Almeida D, Converse PJ, Tyagi S, Li SY, Ammerman NC, Pym AS, Wallengren K, Hafner R, Lalloo U, Swindells S, Bishai WR. Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide. Proceedings of the National Academy of Sciences of the United States of America. 109: 15001-5. PMID 22927424 DOI: 10.1073/pnas.1203636109  0.68
2012 Larsson C, Luna B, Ammerman NC, Maiga M, Agarwal N, Bishai WR. Gene expression of Mycobacterium tuberculosis putative transcription factors whiB1-7 in redox environments. Plos One. 7: e37516. PMID 22829866 DOI: 10.1371/journal.pone.0037516  0.68
2012 Dwivedi VP, Bhattacharya D, Chatterjee S, Prasad DV, Chattopadhyay D, Van Kaer L, Bishai WR, Das G. Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells. The Journal of Biological Chemistry. 287: 33656-63. PMID 22810226 DOI: 10.1074/jbc.M112.375154  0.68
2012 Maiga M, Abaza A, Bishai WR. Current tuberculosis diagnostic tools & role of urease breath test. The Indian Journal of Medical Research. 135: 731-6. PMID 22771606  0.68
2012 Grosset JH, Singer TG, Bishai WR. New drugs for the treatment of tuberculosis: hope and reality. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 16: 1005-14. PMID 22762423 DOI: 10.5588/ijtld.12.0277  0.68
2012 Skerry C, Harper J, Klunk M, Bishai WR, Jain SK. Adjunctive TNF inhibition with standard treatment enhances bacterial clearance in a murine model of necrotic TB granulomas. Plos One. 7: e39680. PMID 22761866 DOI: 10.1371/journal.pone.0039680  0.56
2012 Maiga M, Lun S, Guo H, Winglee K, Ammerman NC, Bishai WR. Risk of tuberculosis reactivation with tofacitinib (CP-690550). The Journal of Infectious Diseases. 205: 1705-8. PMID 22474037 DOI: 10.1093/infdis/jis269  0.68
2012 Pelly S, Bishai WR, Lamichhane G. A screen for non-coding RNA in Mycobacterium tuberculosis reveals a cAMP-responsive RNA that is expressed during infection. Gene. 500: 85-92. PMID 22446041 DOI: 10.1016/j.gene.2012.03.044  1
2012 Lee JH, Ammerman NC, Nolan S, Geiman DE, Lun S, Guo H, Bishai WR. Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis. Nature Communications. 3: 753. PMID 22434196 DOI: 10.1038/ncomms1724  0.68
2012 Maiga M, Agarwal N, Ammerman NC, Gupta R, Guo H, Maiga MC, Lun S, Bishai WR. Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model. Plos One. 7: e30749. PMID 22319585 DOI: 10.1371/journal.pone.0030749  0.68
2012 Lilienkampf A, Pieroni M, Franzblau SG, Bishai WR, Kozikowski AP. Derivatives of 3-isoxazolecarboxylic acid esters - a potent and selective compound class against replicating and nonreplicating Mycobacterium tuberculosis Current Topics in Medicinal Chemistry. 12: 729-734. PMID 22283815 DOI: 10.2174/156802612799984544  0.68
2012 Be NA, Bishai WR, Jain SK. Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. Bmc Microbiology. 12: 7. PMID 22243650 DOI: 10.1186/1471-2180-12-7  0.56
2012 Harper J, Skerry C, Davis SL, Tasneen R, Weir M, Kramnik I, Bishai WR, Pomper MG, Nuermberger EL, Jain SK. Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. The Journal of Infectious Diseases. 205: 595-602. PMID 22198962 DOI: 10.1093/infdis/jir786  0.68
2012 Chopra S, Matsuyama K, Tran T, Malerich JP, Wan B, Franzblau SG, Lun S, Guo H, Maiga MC, Bishai WR, Madrid PB. Evaluation of gyrase B as a drug target in Mycobacterium tuberculosis Journal of Antimicrobial Chemotherapy. 67: 415-421. PMID 22052686 DOI: 10.1093/jac/dkr449  0.68
2012 Grosset JH, Bishai WR. The added effect of thioridazine in the treatment of drug-resistant tuberculosis: Reply International Journal of Tuberculosis and Lung Disease. 16: 1708-1709. DOI: 10.5588/ijtld.12.0616-2  0.68
2011 Olaleye O, Raghunand TR, Bhat S, Chong C, Gu P, Zhou J, Zhang Y, Bishai WR, Liu JO. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: S61-5. PMID 22115541 DOI: 10.1016/j.tube.2011.10.012  0.68
2011 Jain P, Thaler DS, Maiga M, Timmins GS, Bishai WR, Hatfull GF, Larsen MH, Jacobs WR. Reporter phage and breath tests: emerging phenotypic assays for diagnosing active tuberculosis, antibiotic resistance, and treatment efficacy. The Journal of Infectious Diseases. 204: S1142-50. PMID 21996696 DOI: 10.1093/infdis/jir454  0.68
2011 Be NA, Klinkenberg LG, Bishai WR, Karakousis PC, Jain SK. Strain-dependent CNS dissemination in guinea pigs after Mycobacterium tuberculosis aerosol challenge. Tuberculosis (Edinburgh, Scotland). 91: 386-9. PMID 21831713 DOI: 10.1016/j.tube.2011.07.003  0.56
2011 Lamichhane G, Freundlich JS, Ekins S, Wickramaratne N, Nolan ST, Bishai WR. Essential metabolites of Mycobacterium tuberculosis and their mimics. Mbio. 2: e00301-10. PMID 21285434 DOI: 10.1128/mBio.00301-10  0.68
2011 Pieroni M, Tipparaju SK, Lun S, Song Y, Sturm AW, Bishai WR, Kozikowski AP. Pyrido[1,2-a]benzimidazole-Based Agents Active Against Tuberculosis (TB), Multidrug-Resistant (MDR) TB and Extensively Drug-Resistant (XDR) TB Chemmedchem. 6: 334-342. PMID 21259445 DOI: 10.1002/cmdc.201000490  0.68
2011 Festa RA, Jones MB, Butler-Wu S, Sinsimer D, Gerads R, Bishai WR, Peterson SN, Darwin KH. A novel copper-responsive regulon in Mycobacterium tuberculosis. Molecular Microbiology. 79: 133-48. PMID 21166899 DOI: 10.1111/j.1365-2958.2010.07431.x  0.68
2011 Jeena PM, Bishai WR, Pasipanodya JG, Gumbo T. In silico children and the glass mouse model: clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis. Antimicrobial Agents and Chemotherapy. 55: 539-45. PMID 21098246 DOI: 10.1128/AAC.00763-10  0.68
2010 Klinkenberg LG, Lee JH, Bishai WR, Karakousis PC. The stringent response is required for full virulence of Mycobacterium tuberculosis in guinea pigs. The Journal of Infectious Diseases. 202: 1397-404. PMID 20863231 DOI: 10.1086/656524  0.4
2010 Nisa S, Blokpoel MC, Robertson BD, Tyndall JD, Lun S, Bishai WR, O'Toole R. Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery. The Journal of Antimicrobial Chemotherapy. 65: 2347-58. PMID 20810423 DOI: 10.1093/jac/dkq311  0.68
2010 Jassal MS, Nedeltchev GG, Lee JH, Choi SW, Atudorei V, Sharp ZD, Deretic V, Timmins GS, Bishai WR. 13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis. Plos One. 5: e12451. PMID 20805989 DOI: 10.1371/journal.pone.0012451  0.68
2010 Burns KE, Cerda-Maira FA, Wang T, Li H, Bishai WR, Darwin KH. "Depupylation" of prokaryotic ubiquitin-like protein from mycobacterial proteasome substrates. Molecular Cell. 39: 821-7. PMID 20705495 DOI: 10.1016/j.molcel.2010.07.019  0.68
2010 Cerda-Maira FA, Pearce MJ, Fuortes M, Bishai WR, Hubbard SR, Darwin KH. Molecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosis. Molecular Microbiology. 77: 1123-35. PMID 20636328 DOI: 10.1111/j.1365-2958.2010.07276.x  0.68
2010 Converse PJ, Eisenach KD, Theus SA, Nuermberger EL, Tyagi S, Ly LH, Geiman DE, Guo H, Nolan ST, Akar NC, Klinkenberg LG, Gupta R, Lun S, Karakousis PC, Lamichhane G, ... ... Bishai WR, et al. The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models. Plos One. 5: e10289. PMID 20422019 DOI: 10.1371/journal.pone.0010289  1
2010 Gupta R, Lavollay M, Mainardi JL, Arthur M, Bishai WR, Lamichhane G. The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin. Nature Medicine. 16: 466-9. PMID 20305661 DOI: 10.1038/nm.2120  1
2010 Olaleye O, Raghunand TR, Bhat S, He J, Tyagi S, Lamichhane G, Gu P, Zhou J, Zhang Y, Grosset J, Bishai WR, Liu JO. Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets. Chemistry & Biology. 17: 86-97. PMID 20142044 DOI: 10.1016/j.chembiol.2009.12.014  0.68
2010 Greenberg JD, Reed G, Kremer JM, Tindall E, Kavanaugh A, Zheng C, Bishai W, Hochberg MC. Association of methotrexate and tumour necrosis factor antagonists with risk of infectious outcomes including opportunistic infections in the CORRONA registry. Annals of the Rheumatic Diseases. 69: 380-6. PMID 19359261 DOI: 10.1136/ard.2008.089276  0.68
2009 Olaleye OA, Bishai WR, Liu JO. Targeting the role of N-terminal methionine processing enzymes in Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 89: S55-9. PMID 20006307 DOI: 10.1016/S1472-9792(09)70013-7  0.68
2009 Davis SL, Nuermberger EL, Um PK, Vidal C, Jedynak B, Pomper MG, Bishai WR, Jain SK. Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment. Antimicrobial Agents and Chemotherapy. 53: 4879-84. PMID 19738022 DOI: 10.1128/AAC.00789-09  0.68
2009 Ahmad Z, Klinkenberg LG, Pinn ML, Fraig MM, Peloquin CA, Bishai WR, Nuermberger EL, Grosset JH, Karakousis PC. Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig. The Journal of Infectious Diseases. 200: 1136-43. PMID 19686043 DOI: 10.1086/605605  0.4
2009 Rifat D, Bishai WR, Karakousis PC. Phosphate depletion: a novel trigger for Mycobacterium tuberculosis persistence. The Journal of Infectious Diseases. 200: 1126-35. PMID 19686042 DOI: 10.1086/605700  0.4
2009 Maloney E, Stankowska D, Zhang J, Fol M, Cheng QJ, Lun S, Bishai WR, Rajagopalan M, Chatterjee D, Madiraju MV. The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides. Plos Pathogens. 5: e1000534. PMID 19649276 DOI: 10.1371/journal.ppat.1000534  0.68
2009 Davis SL, Be NA, Lamichhane G, Nimmagadda S, Pomper MG, Bishai WR, Jain SK. Bacterial thymidine kinase as a non-invasive imaging reporter for Mycobacterium tuberculosis in live animals. Plos One. 4: e6297. PMID 19606217 DOI: 10.1371/journal.pone.0006297  0.68
2009 Agarwal N, Lamichhane G, Gupta R, Nolan S, Bishai WR. Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase. Nature. 460: 98-102. PMID 19516256 DOI: 10.1038/nature08123  1
2009 Conde MB, Efron A, Loredo C, De Souza GR, Graça NP, Cezar MC, Ram M, Chaudhary MA, Bishai WR, Kritski AL, Chaisson RE. Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial. Lancet (London, England). 373: 1183-9. PMID 19345831 DOI: 10.1016/S0140-6736(09)60333-0  0.68
2009 Be NA, Kim KS, Bishai WR, Jain SK. Pathogenesis of central nervous system tuberculosis. Current Molecular Medicine. 9: 94-9. PMID 19275620 DOI: 10.2174/156652409787581655  0.56
2009 Alahari A, Alibaud L, Trivelli X, Gupta R, Lamichhane G, Reynolds RC, Bishai WR, Guerardel Y, Kremer L. Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis. Molecular Microbiology. 71: 1263-77. PMID 19183278 DOI: 10.1111/j.1365-2958.2009.06604.x  1
2009 Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, Grosset JH, Jain SK, Lamichhane G, Manabe YC, McMurray DN, Nuermberger EL, Bishai WR. Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models. Infection and Immunity. 77: 1230-7. PMID 19103767 DOI: 10.1128/IAI.01117-08  0.68
2009 Nedeltchev GG, Raghunand TR, Jassal MS, Lun S, Cheng QJ, Bishai WR. Extrapulmonary dissemination of Mycobacterium bovis but not Mycobacterium tuberculosis in a bronchoscopic rabbit model of cavitary tuberculosis. Infection and Immunity. 77: 598-603. PMID 19064634 DOI: 10.1128/IAI.01132-08  0.68
2008 Be NA, Lamichhane G, Grosset J, Tyagi S, Cheng QJ, Kim KS, Bishai WR, Jain SK. Murine model to study the invasion and survival of Mycobacterium tuberculosis in the central nervous system. The Journal of Infectious Diseases. 198: 1520-8. PMID 18956986 DOI: 10.1086/592447  1
2008 Klinkenberg LG, Sutherland LA, Bishai WR, Karakousis PC. Metronidazole lacks activity against Mycobacterium tuberculosis in an in vivo hypoxic granuloma model of latency. The Journal of Infectious Diseases. 198: 275-83. PMID 18491971 DOI: 10.1086/589515  0.4
2008 Karakousis PC, Williams EP, Bishai WR. Altered expression of isoniazid-regulated genes in drug-treated dormant Mycobacterium tuberculosis. The Journal of Antimicrobial Chemotherapy. 61: 323-31. PMID 18156607 DOI: 10.1093/jac/dkm485  0.68
2008 Manabe YC, Kesavan AK, Lopez-Molina J, Hatem CL, Brooks M, Fujiwara R, Hochstein K, Pitt ML, Tufariello J, Chan J, McMurray DN, Bishai WR, Dannenberg AM, Mendez S. The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome. Tuberculosis (Edinburgh, Scotland). 88: 187-96. PMID 18068491 DOI: 10.1016/j.tube.2007.10.006  0.68
2008 Lee JH, Karakousis PC, Bishai WR. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. Journal of Bacteriology. 190: 699-707. PMID 17993538 DOI: 10.1128/JB.01273-07  0.4
2008 Jain SK, Lamichhane G, Nimmagadda S, Pomper MG, Bishai WR. Antibiotic treatment of tuberculosis: Old problems, new solutions Microbe. 3: 285-292. DOI: 10.1128/microbe.3.285.1  0.68
2007 Rosenthal IM, Zhang M, Williams KN, Peloquin CA, Tyagi S, Vernon AA, Bishai WR, Chaisson RE, Grosset JH, Nuermberger EL. Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model. Plos Medicine. 4: e344. PMID 18092886 DOI: 10.1371/journal.pmed.0040344  0.68
2007 Almeida D, Nuermberger E, Tyagi S, Bishai WR, Grosset J. In vivo validation of the mutant selection window hypothesis with moxifloxacin in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 51: 4261-6. PMID 17938193 DOI: 10.1128/AAC.01123-07  0.52
2007 Jain SK, Hernandez-Abanto SM, Cheng QJ, Singh P, Ly LH, Klinkenberg LG, Morrison NE, Converse PJ, Nuermberger E, Grosset J, McMurray DN, Karakousis PC, Lamichhane G, Bishai WR. Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice. The Journal of Infectious Diseases. 195: 1634-42. PMID 17471433 DOI: 10.1086/517526  1
2007 Williams EP, Lee JH, Bishai WR, Colantuoni C, Karakousis PC. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. Journal of Bacteriology. 189: 4234-42. PMID 17384187 DOI: 10.1128/JB.00201-07  0.68
2007 Lamichhane G, Bishai W. Defining the 'survivasome' of Mycobacterium tuberculosis. Nature Medicine. 13: 280-2. PMID 17342137 DOI: 10.1038/nm0307-280  1
2007 Agarwal N, Woolwine SC, Tyagi S, Bishai WR. Characterization of the Mycobacterium tuberculosis sigma factor SigM by assessment of virulence and identification of SigM-dependent genes. Infection and Immunity. 75: 452-61. PMID 17088352 DOI: 10.1128/IAI.01395-06  0.68
2006 Lamichhane G, Raghunand TR, Morrison NE, Woolwine SC, Tyagi S, Kandavelou K, Bishai WR. Deletion of a Mycobacterium tuberculosis proteasomal ATPase homologue gene produces a slow-growing strain that persists in host tissues. The Journal of Infectious Diseases. 194: 1233-40. PMID 17041849 DOI: 10.1086/508288  0.68
2006 Raghunand TR, Bishai WR. Mapping essential domains of Mycobacterium smegmatis WhmD: insights into WhiB structure and function. Journal of Bacteriology. 188: 6966-76. PMID 16980499 DOI: 10.1128/JB.00384-06  0.44
2006 Agarwal N, Raghunand TR, Bishai WR. Regulation of the expression of whiB1 in Mycobacterium tuberculosis: role of cAMP receptor protein. Microbiology (Reading, England). 152: 2749-56. PMID 16946269 DOI: 10.1099/mic.0.28924-0  0.44
2006 Raghunand TR, Bishai WR. Mycobacterium smegmatis whmD and its homologue Mycobacterium tuberculosis whiB2 are functionally equivalent. Microbiology (Reading, England). 152: 2735-47. PMID 16946268 DOI: 10.1099/mic.0.28911-0  0.44
2006 Hernandez-Abanto SM, Woolwine SC, Jain SK, Bishai WR. Tetracycline-inducible gene expression in mycobacteria within an animal host using modified Streptomyces tcp830 regulatory elements. Archives of Microbiology. 186: 459-64. PMID 16944099 DOI: 10.1007/s00203-006-0160-2  0.68
2006 Geiman DE, Raghunand TR, Agarwal N, Bishai WR. Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes. Antimicrobial Agents and Chemotherapy. 50: 2836-41. PMID 16870781 DOI: 10.1128/AAC.00295-06  0.44
2006 Nuermberger E, Rosenthal I, Tyagi S, Williams KN, Almeida D, Peloquin CA, Bishai WR, Grosset JH. Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 50: 2621-5. PMID 16870750 DOI: 10.1128/AAC.00451-06  0.68
2006 Raghunand TR, Bishai WR, Chen P. Towards establishing a method to screen for inhibitors of essential genes in mycobacteria: evaluation of the acetamidase promoter. International Journal of Antimicrobial Agents. 28: 36-41. PMID 16757153 DOI: 10.1016/j.ijantimicag.2006.01.012  0.44
2006 Jain SK, Paul-Satyaseela M, Lamichhane G, Kim KS, Bishai WR. Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. The Journal of Infectious Diseases. 193: 1287-95. PMID 16586367 DOI: 10.1086/502631  1
2006 Rosenthal IM, Williams K, Tyagi S, Peloquin CA, Vernon AA, Bishai WR, Grosset JH, Nuermberger EL. Potent twice-weekly rifapentine-containing regimens in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 174: 94-101. PMID 16574936 DOI: 10.1164/rccm.200602-280OC  0.68
2005 Williams KN, Bishai WR. Clarithromycin extended-release in community-acquired respiratory tract infections. Expert Opinion On Pharmacotherapy. 6: 2867-76. PMID 16318437 DOI: 10.1517/14656566.6.16.2867  0.68
2005 Nuermberger E, Tyagi S, Williams KN, Rosenthal I, Bishai WR, Grosset JH. Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model. American Journal of Respiratory and Critical Care Medicine. 172: 1452-6. PMID 16151038 DOI: 10.1164/rccm.200507-1047OC  0.68
2005 Rosenthal IM, Williams K, Tyagi S, Vernon AA, Peloquin CA, Bishai WR, Grosset JH, Nuermberger EL. Weekly moxifloxacin and rifapentine is more active than the denver regimen in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 172: 1457-62. PMID 16141439 DOI: 10.1164/rccm.200507-1072OC  0.68
2005 Ginsburg AS, Sun R, Calamita H, Scott CP, Bishai WR, Grosset JH. Emergence of fluoroquinolone resistance in Mycobacterium tuberculosis during continuously dosed moxifloxacin monotherapy in a mouse model Antimicrobial Agents and Chemotherapy. 49: 3977-3979. PMID 16127087 DOI: 10.1128/AAC.49.9.3977-3979.2005  0.68
2005 Tyagi S, Nuermberger E, Yoshimatsu T, Williams K, Rosenthal I, Lounis N, Bishai W, Grosset J. Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 49: 2289-93. PMID 15917523 DOI: 10.1128/AAC.49.6.2289-2293.2005  0.68
2005 Lamichhane G, Tyagi S, Bishai WR. Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs. Infection and Immunity. 73: 2533-40. PMID 15784600 DOI: 10.1128/IAI.73.4.2533-2540.2005  1
2005 Ginsburg AS, Lee J, Woolwine SC, Grosset JH, Hamzeh FM, Bishai WR. Modeling in vivo pharmacokinetics and pharmacodynamics of moxifloxacin therapy for Mycobacterium tuberculosis infection by using a novel cartridge system. Antimicrobial Agents and Chemotherapy. 49: 853-6. PMID 15673788 DOI: 10.1128/AAC.49.2.853-856.2005  0.68
2005 Calamita H, Ko C, Tyagi S, Yoshimatsu T, Morrison NE, Bishai WR. The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence. Cellular Microbiology. 7: 233-44. PMID 15659067 DOI: 10.1111/j.1462-5822.2004.00454.x  0.68
2004 Williams DL, Torrero M, Wheeler PR, Truman RW, Yoder M, Morrison N, Bishai WR, Gillis TP. Biological implications of Mycobacterium leprae gene expression during infection. Journal of Molecular Microbiology and Biotechnology. 8: 58-72. PMID 15741741 DOI: 10.1159/000082081  0.68
2004 Karakousis PC, Yoshimatsu T, Lamichhane G, Woolwine SC, Nuermberger EL, Grosset J, Bishai WR. Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice. The Journal of Experimental Medicine. 200: 647-57. PMID 15353557 DOI: 10.1084/jem.20040646  0.68
2004 Nuermberger EL, Yoshimatsu T, Tyagi S, Williams K, Rosenthal I, O'Brien RJ, Vernon AA, Chaisson RE, Bishai WR, Grosset JH. Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 170: 1131-4. PMID 15306535 DOI: 10.1164/rccm.200407-885OC  0.68
2004 Rzeszutek M, Wierzbowski A, Hoban DJ, Conly J, Bishai W, Zhanel GG. A review of clinical failures associated with macrolide-resistant Streptococcus pneumoniae International Journal of Antimicrobial Agents. 24: 95-104. PMID 15288306 DOI: 10.1016/j.ijantimicag.2004.03.008  0.68
2004 Sun R, Converse PJ, Ko C, Tyagi S, Morrison NE, Bishai WR. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Molecular Microbiology. 52: 25-38. PMID 15049808 DOI: 10.1111/j.1365-2958.2003.03958.x  0.52
2004 Geiman DE, Kaushal D, Ko C, Tyagi S, Manabe YC, Schroeder BG, Fleischmann RD, Morrison NE, Converse PJ, Chen P, Bishai WR. Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infection and Immunity. 72: 1733-45. PMID 14977982 DOI: 10.1128/IAI.72.3.1733-1745.2004  0.68
2004 Dorman SE, Hatem CL, Tyagi S, Aird K, Lopez-Molina J, Pitt ML, Zook BC, Dannenberg AM, Bishai WR, Manabe YC. Susceptibility to tuberculosis: clues from studies with inbred and outbred New Zealand White rabbits. Infection and Immunity. 72: 1700-5. PMID 14977978 DOI: 10.1128/IAI.72.3.1700-1705.2004  0.56
2004 Nuermberger EL, Yoshimatsu T, Tyagi S, Bishai WR, Grosset JH. Paucibacillary tuberculosis in mice after prior aerosol immunization with Mycobacterium bovis BCG. Infection and Immunity. 72: 1065-71. PMID 14742554 DOI: 10.1128/IAI.72.2.1065-1071.2004  0.68
2004 Nuermberger EL, Yoshimatsu T, Tyagi S, O'Brien RJ, Vernon AN, Chaisson RE, Bishai WR, Grosset JH. Moxifloxacin-containing regimen greatly reduces time to culture conversion in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 169: 421-6. PMID 14578218 DOI: 10.1164/rccm.200310-1380OC  0.68
2003 Ando M, Yoshimatsu T, Ko C, Converse PJ, Bishai WR. Deletion of Mycobacterium tuberculosis sigma factor E results in delayed time to death with bacterial persistence in the lungs of aerosol-infected mice. Infection and Immunity. 71: 7170-2. PMID 14638810 DOI: 10.1128/IAI.71.12.7170-7172.2003  0.68
2003 Ginsburg AS, Hooper N, Parrish N, Dooley KE, Dorman SE, Booth J, Diener-West M, Merz WG, Bishai WR, Sterling TR. Fluoroquinolone resistance in patients with newly diagnosed tuberculosis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 1448-52. PMID 14614666 DOI: 10.1086/379328  0.68
2003 Ginsburg AS, Woolwine SC, Hooper N, Benjamin WH, Bishai WR, Dorman SE, Sterling TR. The rapid development of fluoroquinolone resistance in M. tuberculosis. The New England Journal of Medicine. 349: 1977-8. PMID 14614180 DOI: 10.1056/NEJM200311133492023  0.68
2003 Manabe YC, Dannenberg AM, Tyagi SK, Hatem CL, Yoder M, Woolwine SC, Zook BC, Pitt ML, Bishai WR. Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis. Infection and Immunity. 71: 6004-11. PMID 14500521 DOI: 10.1128/IAI.71.10.6004-6011.2003  0.68
2003 Ginsburg AS, Grosset JH, Bishai WR. Fluoroquinolones, tuberculosis, and resistance. The Lancet. Infectious Diseases. 3: 432-42. PMID 12837348 DOI: 10.1016/S1473-3099(03)00671-6  0.68
2003 Lamichhane G, Zignol M, Blades NJ, Geiman DE, Dougherty A, Grosset J, Broman KW, Bishai WR. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 7213-8. PMID 12775759 DOI: 10.1073/pnas.1231432100  0.68
2003 Ando M, Manabe YC, Converse PJ, Miyazaki E, Harrison R, Murphy JR, Bishai WR. Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. Infection and Immunity. 71: 2584-90. PMID 12704132  0.6
2003 Saviola B, Woolwine SC, Bishai WR. Isolation of acid-inducible genes of Mycobacterium tuberculosis with the use of recombinase-based in vivo expression technology. Infection and Immunity. 71: 1379-88. PMID 12595455 DOI: 10.1128/IAI.71.3.1379-1388.2003  0.68
2003 Comstock GW, Bellete B, Ko C, Coberly J, Chaisson RE, Bishai WR. Whole-blood interferon-γ release assay versus the TST: Newer not better [6] Clinical Infectious Diseases. 36: 1209-1210. DOI: 10.1086/374718  0.32
2002 Park WG, Bishai WR, Chaisson RE, Dorman SE. Performance of the microscopic observation drug susceptibility assay in drug susceptibility testing for Mycobacterium tuberculosis. Journal of Clinical Microbiology. 40: 4750-2. PMID 12454186 DOI: 10.1128/JCM.40.12.4750-4752.2002  0.68
2002 Cronin WA, Golub JE, Lathan MJ, Mukasa LN, Hooper N, Razeq JH, Baruch NG, Mulcahy D, Benjamin WH, Magder LS, Strickland GT, Bishai WR. Molecular epidemiology of tuberculosis in a low- to moderate-incidence state: are contact investigations enough? Emerging Infectious Diseases. 8: 1271-9. PMID 12453355 DOI: 10.3201/eid0811.020261  0.68
2002 Brennan PJ, Terwilliger T, Barry CE, Manca C, Su H, Reed M, Rutter K, Domenech P, Kaplan G, Li YJ, Wagner D, Bermudez LE, Bodnar K, Flynn J, Campos-Neto A, ... ... Bishai WR, et al. The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135. PMID 12408170 DOI: 10.1054/tube.2002.0329  0.68
2002 Fleischmann RD, Alland D, Eisen JA, Carpenter L, White O, Peterson J, DeBoy R, Dodson R, Gwinn M, Haft D, Hickey E, Kolonay JF, Nelson WC, Umayam LA, Ermolaeva M, ... ... Bishai W, et al. Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. Journal of Bacteriology. 184: 5479-90. PMID 12218036 DOI: 10.1128/JB.184.19.5479-5490.2002  0.68
2002 Scott CP, Dos Anjos Filho L, De Queiroz Mello FC, Thornton CG, Bishai WR, Fonseca LS, Kritski AL, Chaisson RE, Manabe YC. Comparison of C18-carboxypropylbetaine and standard N-acetyl-L-cysteine-NaOH processing of respiratory specimens for increasing tuberculosis smear sensitivity in Brazil Journal of Clinical Microbiology. 40: 3219-3222. PMID 12202556 DOI: 10.1128/JCM.40.9.3219-3222.2002  0.68
2002 Kaushal D, Schroeder BG, Tyagi S, Yoshimatsu T, Scott C, Ko C, Carpenter L, Mehrotra J, Manabe YC, Fleischmann RD, Bishai WR. Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH. Proceedings of the National Academy of Sciences of the United States of America. 99: 8330-5. PMID 12060776 DOI: 10.1073/pnas.102055799  0.68
2002 Yoshimatsu T, Nuermberger E, Tyagi S, Chaisson R, Bishai W, Grosset J. Bactericidal activity of increasing daily and weekly doses of moxifloxacin in murine tuberculosis. Antimicrobial Agents and Chemotherapy. 46: 1875-9. PMID 12019103 DOI: 10.1128/AAC.46.6.1875-1879.2002  0.68
2002 Bellete B, Coberly J, Barnes GL, Ko C, Chaisson RE, Comstock GW, Bishai WR. Evaluation of a whole-blood interferon-gamma release assay for the detection of Mycobacterium tuberculosis infection in 2 study populations. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 34: 1449-56. PMID 12015690 DOI: 10.1086/340397  0.32
2002 Manabe YC, Scott CP, Bishai WR. Naturally attenuated, orally administered Mycobacterium microti as a tuberculosis vaccine is better than subcutaneous Mycobacterium bovis BCG Infection and Immunity. 70: 1566-1570. PMID 11854245 DOI: 10.1128/IAI.70.3.1566-1570.2002  0.68
2002 Oursler KK, Moore RD, Bishai WR, Harrington SM, Pope DS, Chaisson RE. Survival of patients with pulmonary tuberculosis: clinical and molecular epidemiologic factors. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 34: 752-9. PMID 11850859 DOI: 10.1086/338784  0.68
2002 Woolwine SC, Bishai WR. Mycobacterial genetics: the sensibility of antisense. American Journal of Respiratory and Critical Care Medicine. 165: 318-9. PMID 11818312 DOI: 10.1164/ajrccm.165.3.2112045b  0.68
2001 Golub JE, Cronin WA, Obasanjo OO, Coggin W, Moore K, Pope DS, Thompson D, Sterling TR, Harrington S, Bishai WR, Chaisson RE. Transmission of Mycobacterium tuberculosis through casual contact with an infectious case. Archives of Internal Medicine. 161: 2254-8. PMID 11575983 DOI: 10.1001/archinte.161.18.2254  0.68
2001 Cronin WA, Golub JE, Magder LS, Baruch NG, Lathan MJ, Mukasa LN, Hooper N, Razeq JH, Mulcahy D, Benjamin WH, Bishai WR. Epidemiologic usefulness of spoligotyping for secondary typing of Mycobacterium tuberculosis isolates with low copy numbers of IS6110 Journal of Clinical Microbiology. 39: 3709-3711. PMID 11574598 DOI: 10.1128/JCM.39.10.3709-3711.2001  0.68
2000 Chen P, Ruiz RE, Li Q, Silver RF, Bishai WR. Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF Infection and Immunity. 68: 5575-5580. PMID 10992456 DOI: 10.1128/IAI.68.10.5575-5580.2000  0.68
2000 Gomez JE, Bishai WR. whmD is an essential mycobacterial gene required for proper septation and cell division Proceedings of the National Academy of Sciences of the United States of America. 97: 8554-8559. PMID 10880571 DOI: 10.1073/pnas.140225297  0.68
2000 Ellingson JLE, Stabel JR, Bishai WR, Frothingham R, Miller JM. Evaluation of the accuracy and reproducibility of a practical PCR panel assay for rapid detection and differentiation of Mycobacterium avium subspecies Molecular and Cellular Probes. 14: 153-161. PMID 10860713 DOI: 10.1006/mcpr.2000.0299  0.68
2000 Sterling TR, Pope DS, Bishai WR, Harrington S, Gershon RR, Chaisson RE. Transmission of Mycobacterium tuberculosis from a cadaver to an embalmer. The New England Journal of Medicine. 342: 246-8. PMID 10648766 DOI: 10.1056/NEJM200001273420404  0.68
1999 Manabe YC, Saviola BJ, Sun L, Murphy JR, Bishai WR. Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12844-8. PMID 10536010  0.6
1999 Head SR, Parikh K, Rogers YH, Bishai W, Goelet P, Boyce-Jacino MT. Solid-phase sequence scanning for drug resistance detection in tuberculosis Molecular and Cellular Probes. 13: 81-87. PMID 10208797 DOI: 10.1006/mcpr.1998.0212  0.68
1998 Bishai WR, Graham NM, Harrington S, Pope DS, Hooper N, Astemborski J, Sheely L, Vlahov D, Glass GE, Chaisson RE. Molecular and geographic patterns of tuberculosis transmission after 15 years of directly observed therapy. Jama. 280: 1679-84. PMID 9831999 DOI: 10.1001/jama.280.19.1679  0.68
1997 Gomez JE, Chen JM, Bishai WR. Sigma factors of mycobacterium tuberculosis Tubercle and Lung Disease. 78: 175-183. PMID 9713650 DOI: 10.1016/S0962-8479(97)90024-1  0.68
1997 Bishai WR, Chaisson RE. Short-course chemoprophylaxis for tuberculosis Clinics in Chest Medicine. 18: 115-122. PMID 9098615 DOI: 10.1016/S0272-5231(05)70360-9  0.68
1996 Jacobs W, Brennan P, Curlin G, Ginsberg A, Adams M, Fleischmann R, Fraser C, Venter JC, Shinnick T, Bishai W, Smith H, Stover K, Hatfull G. Comparative sequencing. Science (New York, N.Y.). 274: 17-8. PMID 8848713 DOI: 10.1126/science.274.5284.17a  0.68
1995 Howard NS, Gomez JE, Ko C, Bishai WR. Color selection with a hygromycin-resistance-based Escherichia coli-mycobacterial shuttle vector Gene. 166: 181-182. PMID 8529888 DOI: 10.1016/0378-1119(95)00597-X  0.68
1994 Bishai WR, Smith HO, Barcak GJ. A peroxide/ascorbate-inducible catalase from Haemophilus influenzae is homologous to the Escherichia coli katE gene product. Journal of Bacteriology. 176: 2914-21. PMID 8188593  0.68
1994 Bishai WR, Howard NS, Winkelstein JA, Smith HO. Characterization and virulence analysis of catalase mutants of Haemophilus influenzae. Infection and Immunity. 62: 4855-60. PMID 7927766  0.68
1988 Murphy JR, Williams DP, Bacha P, Bishai W, Waters C, Strom TB. Cell receptor specific targeted toxins: Genetic construction and characterization of an interleukin 2 diphtheria toxin-related fusion protein Journal of Receptors and Signal Transduction. 8: 467-480. PMID 3133472 DOI: 10.3109/10799898809049005  0.68
1987 Bishai WR, Miyanohara A, Murphy JR. Cloning and expression in Escherichia coli of three fragments of diphtheria toxin truncated within fragment B. Journal of Bacteriology. 169: 1554-63. PMID 3549695  0.6
1987 Bishai WR, Rappuoli R, Murphy JR. High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli. Journal of Bacteriology. 169: 5140-51. PMID 3312166  0.6
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