| Year |
Citation |
Score |
| 2023 |
Zhang Y, Pan YD, Zheng WY, Li HY, Zhu MZ, Ou Yang WJ, Qian Y, Turecki G, Mechawar N, Zhu XH. Enhancing HIF-1α-P2X2 signaling in dorsal raphe serotonergic neurons promotes psychological resilience. Redox Biology. 69: 103005. PMID 38150991 DOI: 10.1016/j.redox.2023.103005 |
0.445 |
|
| 2023 |
Barde S, Aguila J, Zhong W, Solarz A, Mei I, Prud'homme J, Palkovits M, Turecki G, Mulder J, Uhlén M, Nagy C, Mechawar N, Hedlund E, Hökfelt T. Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 78: 54-63. PMID 37931511 DOI: 10.1016/j.euroneuro.2023.09.004 |
0.507 |
|
| 2023 |
Wakid M, Almeida D, Aouabed Z, Rahimian R, Davoli MA, Yerko V, Leonova-Erko E, Richard V, Zahedi R, Borchers C, Turecki G, Mechawar N. Universal method for the isolation of microvessels from frozen brain tissue: A proof-of-concept multiomic investigation of the neurovasculature. Brain, Behavior, & Immunity - Health. 34: 100684. PMID 37822873 DOI: 10.1016/j.bbih.2023.100684 |
0.79 |
|
| 2023 |
Lin R, Kos A, Lopez JP, Dine J, Fiori LM, Yang J, Ben-Efraim Y, Aouabed Z, Ibrahim P, Mitsuhashi H, Wong TP, Ibrahim EC, Belzung C, Blier P, Farzan F, ... ... Mechawar N, et al. induces glutamatergic signaling following treatment with monoaminergic antidepressants. Elife. 12. PMID 37432876 DOI: 10.7554/eLife.85316 |
0.471 |
|
| 2023 |
Maitra M, Mitsuhashi H, Rahimian R, Chawla A, Yang J, Fiori LM, Davoli MA, Perlman K, Aouabed Z, Mash DC, Suderman M, Mechawar N, Turecki G, Nagy C. Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes. Nature Communications. 14: 2912. PMID 37217515 DOI: 10.1038/s41467-023-38530-5 |
0.443 |
|
| 2023 |
Poisel E, Zillich L, Streit F, Frank J, Friske MM, Foo JC, Mechawar N, Turecki G, Hansson AC, Nöthen MM, Rietschel M, Spanagel R, Witt SH. DNA methylation in cocaine use disorder-An epigenome-wide approach in the human prefrontal cortex. Frontiers in Psychiatry. 14: 1075250. PMID 36865068 DOI: 10.3389/fpsyt.2023.1075250 |
0.394 |
|
| 2023 |
Matosin N, Arloth J, Czamara D, Edmond KZ, Maitra M, Fröhlich AS, Martinelli S, Kaul D, Bartlett R, Curry AR, Gassen NC, Hafner K, Müller NS, Worf K, Rehawi G, ... ... Mechawar N, et al. Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. Acta Neuropathologica. PMID 36729133 DOI: 10.1007/s00401-023-02541-9 |
0.472 |
|
| 2022 |
Belliveau C, Mechawar N, Tanti A. Reply to: "NG2-glia: rising stars in stress-related mental disorders?". Molecular Psychiatry. PMID 36481933 DOI: 10.1038/s41380-022-01889-w |
0.657 |
|
| 2022 |
Reemst K, Kracht L, Kotah JM, Rahimian R, van Irsen AAS, Congrains Sotomayor G, Verboon LN, Brouwer N, Simard S, Turecki G, Mechawar N, Kooistra SM, Eggen BJL, Korosi A. Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions. Translational Psychiatry. 12: 507. PMID 36481769 DOI: 10.1038/s41398-022-02265-6 |
0.428 |
|
| 2022 |
Lacombe RJS, Smith ME, Perlman K, Turecki G, Mechawar N, Bazinet RP. Quantitative and Carbon Isotope Ratio Analysis of Fatty Acids Isolated from Human Brain Hemispheres. Journal of Neurochemistry. PMID 36196762 DOI: 10.1111/jnc.15702 |
0.36 |
|
| 2022 |
Zhong W, Barde S, Mitsios N, Adori C, Oksvold P, Feilitzen KV, O'Leary L, Csiba L, Hortobágyi T, Szocsics P, Mechawar N, Maglóczky Z, Renner É, Palkovits M, Uhlén M, et al. The neuropeptide landscape of human prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123146119. PMID 35947618 DOI: 10.1073/pnas.2123146119 |
0.632 |
|
| 2022 |
Santana DA, Bedrat A, Puga RD, Turecki G, Mechawar N, Faria TC, Gigek CO, Payão SL, Smith MA, Lemos B, Chen ES. The role of H3K9 acetylation and gene expression in different brain regions of Alzheimer's disease patients. Epigenomics. PMID 35588246 DOI: 10.2217/epi-2022-0096 |
0.417 |
|
| 2022 |
Dion-Albert L, Cadoret A, Doney E, Kaufmann FN, Dudek KA, Daigle B, Parise LF, Cathomas F, Samba N, Hudson N, Lebel M, Campbell M, Turecki G, Mechawar N, et al. Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue. Nature Communications. 13: 164. PMID 35013188 DOI: 10.1038/s41467-021-27604-x |
0.775 |
|
| 2021 |
Belliveau C, Nagy C, Escobar S, Mechawar N, Turecki G, Rej S, Torres-Platas SG. Effects of Mindfulness-Based Cognitive Therapy on Peripheral Markers of Stress and Inflammation in Older-Adults With Depression and Anxiety: A Parallel Analysis of a Randomized Controlled Trial. Frontiers in Psychiatry. 12: 804269. PMID 35002817 DOI: 10.3389/fpsyt.2021.804269 |
0.755 |
|
| 2021 |
Almeida D, Fiori LM, Chen GG, Aouabed Z, Lutz PE, Zhang TY, Mechawar N, Meaney MJ, Turecki G. Oxytocin receptor expression and epigenetic regulation in the anterior cingulate cortex of individuals with a history of severe childhood abuse. Psychoneuroendocrinology. 136: 105600. PMID 34839083 DOI: 10.1016/j.psyneuen.2021.105600 |
0.722 |
|
| 2021 |
Tanti A, Belliveau C, Nagy C, Maitra M, Denux F, Perlman K, Chen F, Mpai R, Canonne C, Théberge S, McFarquhar A, Davoli MA, Belzung C, Turecki G, Mechawar N. Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells. Molecular Psychiatry. PMID 34799691 DOI: 10.1038/s41380-021-01372-y |
0.759 |
|
| 2021 |
Vaillancourt K, Chen GG, Fiori L, Maussion G, Yerko V, Théroux JF, Ernst C, Labonté B, Calipari E, Nestler EJ, Nagy C, Mechawar N, Mash DC, Turecki G. Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum. Iscience. 24: 103169. PMID 34693223 DOI: 10.1016/j.isci.2021.103169 |
0.372 |
|
| 2021 |
Andrianarivelo A, Saint-Jour E, Pousinha P, Fernandez SP, Petitbon A, De Smedt-Peyrusse V, Heck N, Ortiz V, Allichon MC, Kappès V, Betuing S, Walle R, Zhu Y, Joséphine C, Bemelmans AP, ... ... Mechawar N, et al. Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing. Science Advances. 7: eabg5970. PMID 34669474 DOI: 10.1126/sciadv.abg5970 |
0.32 |
|
| 2021 |
Perlman K, Chouinard-Watkins R, Tanti A, Cisbani G, Orri M, Turecki G, Bazinet RP, Mechawar N. Fatty acid dysregulation in the anterior cingulate cortex of depressed suicides with a history of child abuse. Translational Psychiatry. 11: 535. PMID 34663786 DOI: 10.1038/s41398-021-01657-4 |
0.749 |
|
| 2021 |
Perlman G, Tanti A, Mechawar N. Parvalbumin interneuron alterations in stress-related mood disorders: A systematic review. Neurobiology of Stress. 15: 100380. PMID 34557569 DOI: 10.1016/j.ynstr.2021.100380 |
0.714 |
|
| 2021 |
Rahimian R, Wakid M, O'Leary LA, Mechawar N. The emerging tale of microglia in psychiatric disorders. Neuroscience and Biobehavioral Reviews. 131: 1-29. PMID 34536460 DOI: 10.1016/j.neubiorev.2021.09.023 |
0.804 |
|
| 2021 |
Saeedi S, Nagy C, Ibrahim P, Théroux JF, Wakid M, Fiori LM, Yang J, Rotzinger S, Foster JA, Mechawar N, Kennedy SH, Turecki G. Neuron-derived extracellular vesicles enriched from plasma show altered size and miRNA cargo as a function of antidepressant drug response. Molecular Psychiatry. PMID 34385599 DOI: 10.1038/s41380-021-01255-2 |
0.768 |
|
| 2021 |
Bell S, McCarty V, Peng H, Jefri M, Hettige N, Antonyan L, Crapper L, O'Leary LA, Zhang X, Zhang Y, Wu H, Sutcliffe D, Kolobova I, Rosenberger TA, Moquin L, ... ... Mechawar N, et al. Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells. Stem Cell Reports. PMID 34214487 DOI: 10.1016/j.stemcr.2021.06.003 |
0.597 |
|
| 2021 |
Maitra M, Nagy C, Chawla A, Wang YC, Nascimento C, Suderman M, Théroux JF, Mechawar N, Ragoussis J, Turecki G. Extraction of nuclei from archived postmortem tissues for single-nucleus sequencing applications. Nature Protocols. PMID 33972803 DOI: 10.1038/s41596-021-00514-4 |
0.333 |
|
| 2021 |
O'Leary LA, Mechawar N. Implication of cerebral astrocytes in major depression: A review of fine neuroanatomical evidence in humans. Glia. PMID 33734498 DOI: 10.1002/glia.23994 |
0.68 |
|
| 2021 |
O'Leary LA, Belliveau C, Davoli MA, Ma JC, Tanti A, Turecki G, Mechawar N. Widespread Decrease of Cerebral Vimentin-Immunoreactive Astrocytes in Depressed Suicides. Frontiers in Psychiatry. 12: 640963. PMID 33613346 DOI: 10.3389/fpsyt.2021.640963 |
0.823 |
|
| 2021 |
Lutz PE, Chay MA, Pacis A, Chen GG, Aouabed Z, Maffioletti E, Théroux JF, Grenier JC, Yang J, Aguirre M, Ernst C, Redensek A, van Kempen LC, Yalcin I, Kwan T, ... Mechawar N, et al. Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation. Nature Communications. 12: 1132. PMID 33602921 DOI: 10.1038/s41467-021-21365-3 |
0.405 |
|
| 2020 |
Fiori LM, Kos A, Lin R, Théroux JF, Lopez JP, Kühne C, Eggert C, Holzapfel M, Huettl RE, Mechawar N, Belzung C, Ibrahim EC, Chen A, Turecki G. miR-323a regulates ERBB4 and is involved in depression. Molecular Psychiatry. PMID 33219358 DOI: 10.1038/s41380-020-00953-7 |
0.394 |
|
| 2020 |
Vaillancourt K, Yang J, Chen GG, Yerko V, Théroux JF, Aouabed Z, Lopez A, Thibeault KC, Calipari ES, Labonté B, Mechawar N, Ernst C, Nagy C, Forné T, Nestler EJ, et al. Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. Molecular Psychiatry. PMID 33046833 DOI: 10.1038/s41380-020-00909-x |
0.368 |
|
| 2020 |
O'Leary LA, Davoli MA, Belliveau C, Tanti A, Ma JC, Farmer WT, Turecki G, Murai KK, Mechawar N. Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain. Frontiers in Neuroanatomy. 14: 31. PMID 32848635 DOI: 10.3389/Fnana.2020.00031 |
0.798 |
|
| 2020 |
Nagy C, Maitra M, Tanti A, Suderman M, Théroux JF, Davoli MA, Perlman K, Yerko V, Wang YC, Tripathy SJ, Pavlidis P, Mechawar N, Ragoussis J, Turecki G. Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons. Nature Neuroscience. PMID 32341540 DOI: 10.1038/S41593-020-0621-Y |
0.779 |
|
| 2020 |
Belzeaux R, Gorgievski V, Fiori LM, Lopez JP, Grenier J, Lin R, Nagy C, Ibrahim EC, Gascon E, Courtet P, Richard-Devantoy S, Berlim M, Chachamovich E, Théroux JF, Dumas S, ... ... Mechawar N, et al. GPR56/ADGRG1 is associated with response to antidepressant treatment. Nature Communications. 11: 1635. PMID 32242018 DOI: 10.1038/S41467-020-15423-5 |
0.55 |
|
| 2020 |
Faria TC, Maldonado HL, Santos LC, DeLabio R, Payao SLM, Turecki G, Mechawar N, Santana DA, Gigek CO, Lemos B, Smith MAC, Chen ES. Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Disease: Should the Cerebellum Serve as a Control Tissue After All? Molecular Neurobiology. PMID 32232768 DOI: 10.1007/S12035-020-01902-9 |
0.485 |
|
| 2020 |
Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Theroux JF, Moquin L, Zhang X, Aouabed Z, Krishnan J, O'Leary LA, Antonyan L, ... ... Mechawar N, et al. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. Stem Cells Translational Medicine. PMID 32154672 DOI: 10.1002/Sctm.18-0180 |
0.62 |
|
| 2020 |
Dudek KA, Dion-Albert L, Lebel M, LeClair K, Labrecque S, Tuck E, Ferrer Perez C, Golden SA, Tamminga C, Turecki G, Mechawar N, Russo SJ, Menard C. Molecular adaptations of the blood-brain barrier promote stress resilience vs. depression. Proceedings of the National Academy of Sciences of the United States of America. PMID 31974313 DOI: 10.1073/Pnas.1914655117 |
0.798 |
|
| 2020 |
Perlman K, Couturier CP, Yaqubi M, Tanti A, Cui QL, Pernin F, Stratton JA, Ragoussis J, Healy L, Petrecca K, Dudley R, Srour M, Hall JA, Kennedy TE, Mechawar N, et al. Developmental trajectory of oligodendrocyte progenitor cells in the human brain revealed by single cell RNA sequencing. Glia. PMID 31958186 DOI: 10.1002/Glia.23777 |
0.707 |
|
| 2020 |
Labonté B, Abdallah K, Maussion G, Yerko V, Yang J, Bittar T, Quessy F, Golden SA, Navarro L, Checknita D, Gigek C, Lopez JP, Neve RL, Russo SJ, Tremblay RE, ... ... Mechawar N, et al. Regulation of impulsive and aggressive behaviours by a novel lncRNA. Molecular Psychiatry. PMID 31907380 DOI: 10.1038/S41380-019-0637-4 |
0.511 |
|
| 2020 |
Tanti A, Nagy C, Maitra M, Wakid M, Turecki G, Mechawar N. A Post-Mortem Investigation of Perivascular Oligodendrocyte Precursor Cells in the Prefrontal Cortex of Major Depressed Patients Biological Psychiatry. 87: S91. DOI: 10.1016/J.Biopsych.2020.02.254 |
0.807 |
|
| 2020 |
Nagy C, Maitra M, Tanti A, Suderman M, Théroux J, Tripathy S, Pavlidis P, Mechawar N, Turecki G. Single-Cell Genomic Strategies to Understand Psychopathological Processes in Depression and Suicide Biological Psychiatry. 87: S43. DOI: 10.1016/J.Biopsych.2020.02.134 |
0.758 |
|
| 2020 |
Anna Dudek K, Dion-Albert L, Lebel M, LeClair K, Labrecque S, Tuck E, Ferrer Perez C, Golden S, Tamminga C, Turecki G, Mechawar N, Russo S, Menard C. Social Stress Induces Blood-Brain Barrier Leakiness and Molecular Alterations Promoting Depression or Stress Resilience Biological Psychiatry. 87: S14-S15. DOI: 10.1016/J.Biopsych.2020.02.064 |
0.768 |
|
| 2019 |
Tanti A, Lutz PE, Kim J, O'Leary L, Théroux JF, Turecki G, Mechawar N. Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31374562 DOI: 10.1038/S41386-019-0471-Z |
0.832 |
|
| 2019 |
Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration. Scientific Reports. 9: 7850. PMID 31127135 DOI: 10.1038/S41598-019-43955-4 |
0.701 |
|
| 2019 |
Pizzagalli DA, Berretta S, Wooten D, Goer F, Pilobello KT, Kumar P, Murray L, Beltzer M, Boyer-Boiteau A, Alpert N, El Fakhri G, Mechawar N, Vitaliano G, Turecki G, Normandin M. Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence. Jama Psychiatry. PMID 31042280 DOI: 10.1001/Jamapsychiatry.2019.0801 |
0.475 |
|
| 2019 |
Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Theroux JF, Jefri M, Tanti A, Wu H, Kolobova I, Silviera H, Manzano-Vargas K, Ehresmann S, Hamdan FF, Hettige N, ... ... Mechawar N, et al. Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. American Journal of Human Genetics. PMID 31031012 DOI: 10.1016/J.Ajhg.2019.03.022 |
0.734 |
|
| 2019 |
Salamanca L, Mechawar N, Murai KK, Balling R, Bouvier DS, Skupin A. MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples. Glia. PMID 30983036 DOI: 10.1002/Glia.23623 |
0.331 |
|
| 2019 |
Xiong W, Cao X, Zeng Y, Qin X, Zhu M, Ren J, Wu Z, Huang Q, Zhang Y, Wang M, Chen L, Turecki G, Mechawar N, Chen W, Yi G, et al. Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30902874 DOI: 10.1523/Jneurosci.3069-18.2019 |
0.57 |
|
| 2019 |
Menard C, Dudek K, Dion-Albert L, Lebel M, Leclair K, Tuck E, Perez CF, Golden SA, Mechawar N, Russo SJ. Molecular adaptations of the blood-brain barrier promoting depression or stress resilience Ibro Reports. 6: S239. DOI: 10.1016/J.Ibror.2019.07.744 |
0.755 |
|
| 2019 |
Mechawar N, Tanti A, Turecki G. 202. Impaired Astrocyte-Oligodendrocyte Gap Junction Coupling in the Anterior Cingulate Cortex of Depressed Suicides Biological Psychiatry. 85: S84. DOI: 10.1016/J.Biopsych.2019.03.216 |
0.774 |
|
| 2019 |
Almeida D, Chen G, Theroux J, Aouabed Z, Davoli MA, Mechawar N, Turecki G. 59. LCM-Seq: Pyramidal Neuron Transcriptomic Profiling in the Prefrontal Cortex of Abused Suicides Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.073 |
0.743 |
|
| 2018 |
Hökfelt T, Barde S, Xu ZD, Kuteeva E, Rüegg J, Le Maitre E, Risling M, Kehr J, Ihnatko R, Theodorsson E, Palkovits M, Deakin W, Bagdy G, Juhasz G, Prud'homme HJ, ... Mechawar N, et al. Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness. Frontiers in Neural Circuits. 12: 106. PMID 30627087 DOI: 10.3389/Fncir.2018.00106 |
0.475 |
|
| 2018 |
Ehrlich AT, Maroteaux G, Robe A, Venteo L, Nasseef MT, van Kempen LC, Mechawar N, Turecki G, Darcq E, Kieffer BL. Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research. Communications Biology. 1: 102. PMID 30271982 DOI: 10.1038/s42003-018-0106-7 |
0.413 |
|
| 2018 |
Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, ... Mechawar N, et al. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nature Communications. 9: 2459. PMID 29941989 DOI: 10.1038/S41467-018-04883-5 |
0.759 |
|
| 2018 |
Bell S, Maussion G, Jefri M, Peng H, Theroux JF, Silveira H, Soubannier V, Wu H, Hu P, Galat E, Torres-Platas SG, Boudreau-Pinsonneault C, O'Leary LA, Galat V, Turecki G, ... ... Mechawar N, et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons. Stem Cell Reports. PMID 29937144 DOI: 10.1016/J.Stemcr.2018.05.018 |
0.776 |
|
| 2018 |
Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP, Grenier J, Ibrahim EC, El Khoury MA, Tse YC, Mongredien R, Barbé A, de Macedo CEA, Jaworski W, Bochereau A, Orrico A, ... ... Mechawar N, et al. Antidepressive effects of targeting ELK-1 signal transduction. Nature Medicine. PMID 29736027 DOI: 10.1038/S41591-018-0011-0 |
0.541 |
|
| 2018 |
Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor. Neuroimage. PMID 29704613 DOI: 10.1016/J.Neuroimage.2018.04.054 |
0.681 |
|
| 2018 |
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Mechawar N, et al. Corrigendum: Sex-specific transcriptional signatures in human depression. Nature Medicine. 24: 525. PMID 29634684 DOI: 10.1038/Nm0418-525D |
0.764 |
|
| 2018 |
Lutz P, Chay M, Théroux J, Kwan T, Redensek A, Mechawar N, Pastinen T, Turecki G. 18. Dysregulation of Non-Cg Methylation by Child Abuse Biological Psychiatry. 83: S7. DOI: 10.1016/J.Biopsych.2018.02.035 |
0.406 |
|
| 2017 |
Han S, Yang SH, Kim JY, Mo S, Yang E, Song KM, Ham BJ, Mechawar N, Turecki G, Lee HW, Kim H. Author Correction: Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Scientific Reports. 7: 17090. PMID 29196669 DOI: 10.1038/S41598-017-16991-1 |
0.406 |
|
| 2017 |
Tanti A, Kim JJ, Wakid M, Davoli MA, Turecki G, Mechawar N. Child abuse associates with an imbalance of oligodendrocyte-lineage cells in ventromedial prefrontal white matter. Molecular Psychiatry. PMID 29158585 DOI: 10.1038/mp.2017.231 |
0.811 |
|
| 2017 |
Rocco BR, Oh H, Shukla R, Mechawar N, Sibille E. Fluorescence-based cell-specific detection for laser-capture microdissection in human brain. Scientific Reports. 7: 14213. PMID 29079825 DOI: 10.1038/S41598-017-14484-9 |
0.311 |
|
| 2017 |
Lin MS, Xiong WC, Li SJ, Gong Z, Cao X, Kuang XJ, Zhang Y, Gao TM, Mechawar N, Liu C, Zhu XH. α2-Glycine receptors modulate adult hippocampal neurogenesis and spatial memory. Developmental Neurobiology. PMID 29057625 DOI: 10.1002/Dneu.22549 |
0.316 |
|
| 2017 |
Mahar I, Labonte B, Yogendran S, Isingrini E, Perret L, Davoli MA, Rachalski A, Giros B, Turecki G, Mechawar N. Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide. Translational Psychiatry. 7: e1243. PMID 28949336 DOI: 10.1038/Tp.2017.214 |
0.77 |
|
| 2017 |
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Mechawar N, et al. Sex-specific transcriptional signatures in human depression. Nature Medicine. PMID 28825715 DOI: 10.1038/Nm.4386 |
0.784 |
|
| 2017 |
Lutz PE, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D, Chay MA, Yang J, Larivière V, M'Boutchou MN, van Kempen LC, ... ... Mechawar N, et al. Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence. The American Journal of Psychiatry. appiajp201716111286. PMID 28750583 DOI: 10.1176/Appi.Ajp.2017.16111286 |
0.792 |
|
| 2017 |
Pabba M, Scifo E, Kapadia F, Nikolova YS, Ma T, Mechawar N, Tseng GC, Sibille E. Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging. Neurobiology of Aging. 58: 180-190. PMID 28750307 DOI: 10.1016/J.Neurobiolaging.2017.06.023 |
0.304 |
|
| 2017 |
Mahar I, Labonte B, Yogendran S, Isingrini E, Perret L, Davoli MA, Rachalski A, Giros B, Turecki G, Mechawar N. Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide. Translational Psychiatry. 7: e1161. PMID 28675388 DOI: 10.1038/tp.2017.132 |
0.305 |
|
| 2017 |
Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, ... ... Mechawar N, et al. MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications. 8: 15497. PMID 28530238 DOI: 10.1038/Ncomms15497 |
0.464 |
|
| 2017 |
Han S, Yang SH, Kim JY, Mo S, Yang E, Song KM, Ham BJ, Mechawar N, Turecki G, Lee HW, Kim H. Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Scientific Reports. 7: 900. PMID 28420875 DOI: 10.1038/S41598-017-01088-6 |
0.561 |
|
| 2017 |
Chen GG, Gross JA, Lutz PE, Vaillancourt K, Maussion G, Bramoulle A, Théroux JF, Gardini ES, Ehlert U, Bourret G, Masurel A, Lepage P, Mechawar N, Turecki G, Ernst C. Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine. Bmc Genomics. 18: 96. PMID 28100169 DOI: 10.1186/S12864-017-3489-9 |
0.411 |
|
| 2017 |
Kelaï S, Ramoz N, Moalic JM, Noble F, Mechawar N, Imbeaud S, Turecki G, Simonneau M, Gorwood P, Maussion G. Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence. Addiction Biology. PMID 28074533 DOI: 10.1111/Adb.12485 |
0.432 |
|
| 2017 |
Gasecka A, Tanti A, Lutz P, Mechawar N, Cote DC. Subtle changes in myelination due to childhood experiences: label-free microscopy to infer nerve fibers morphology and myelination in brain (Conference Presentation) Proceedings of Spie. 10051. DOI: 10.1117/12.2253507 |
0.686 |
|
| 2017 |
Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. 695. Resilience against Chronic Stress is Mediated by Noradrenergic Regulation of the Ventral Tegmental Area Biological Psychiatry. 81: S282. DOI: 10.1016/J.Biopsych.2017.02.762 |
0.683 |
|
| 2017 |
Mechawar N, Lutz P, Tanti A, Gasecka A, Kim J, Wakid M, Côté D, Turecki G. 110. Early Life Adversity Associates with Altered Oligodendrocyte Function and Decreased Myelination in the Anterior Cingulate Cortex of Depressed Suicides Biological Psychiatry. 81: S46. DOI: 10.1016/J.Biopsych.2017.02.122 |
0.809 |
|
| 2016 |
Mahar I, Albuquerque MS, Mondragon-Rodriguez S, Cavanagh C, Davoli MA, Chabot JG, Williams S, Mechawar N, Quirion R, Krantic S. Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer's Disease. Frontiers in Aging Neuroscience. 8: 327. PMID 28154533 DOI: 10.3389/Fnagi.2016.00327 |
0.772 |
|
| 2016 |
Barde S, Rüegg J, Prud'homme J, Ekström TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G, Diaz-Heijtz R, Mechawar N, Hökfelt TG. Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940914 DOI: 10.1073/Pnas.1617824113 |
0.572 |
|
| 2016 |
Mechawar N, Savitz J. Neuropathology of mood disorders: do we see the stigmata of inflammation? Translational Psychiatry. 6: e946. PMID 27824355 DOI: 10.1038/Tp.2016.212 |
0.439 |
|
| 2016 |
Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G. Global and site-specific changes in 5-methylcytosine and 5-hydroxymethylcytosine after extended post-mortem interval. Experimental and Molecular Pathology. PMID 27746278 DOI: 10.1016/J.Yexmp.2016.10.004 |
0.783 |
|
| 2016 |
Nagy C, Torres-Platas SG, Mechawar N, Turecki G. Repression of astrocytic connexins in cortical and subcortical brain regions and prefrontal enrichment of H3K9me3 in depression and suicide. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 27516431 DOI: 10.1093/Ijnp/Pyw071 |
0.812 |
|
| 2016 |
Mahar I, MacIsaac A, Kim JJ, Qiang C, Davoli MA, Turecki G, Mechawar N. Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis. Scientific Reports. 6: 30467. PMID 27469430 DOI: 10.1038/Srep30467 |
0.782 |
|
| 2016 |
Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G. Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval. Frontiers in Genetics. 7: 120. PMID 27446202 DOI: 10.3389/Fgene.2016.00120 |
0.783 |
|
| 2016 |
Huh CY, Amilhon B, Ferguson KA, Manseau F, Torres-Platas SG, Peach JP, Scodras S, Mechawar N, Skinner FK, Williams S. Excitatory Inputs Determine Phase-Locking Strength and Spike-Timing of CA1 Stratum Oriens/Alveus Parvalbumin and Somatostatin Interneurons during Intrinsically Generated Hippocampal Theta Rhythm. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6605-22. PMID 27335395 DOI: 10.1523/Jneurosci.3951-13.2016 |
0.712 |
|
| 2016 |
Trépanier MO, Hopperton KE, Mizrahi R, Mechawar N, Bazinet RP. Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review. Molecular Psychiatry. 21: 1009-26. PMID 27271499 DOI: 10.1038/Mp.2016.90 |
0.321 |
|
| 2016 |
Bouvier DS, Jones EV, Quesseveur G, Davoli MA, A Ferreira T, Quirion R, Mechawar N, Murai KK. High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease. Scientific Reports. 6: 24544. PMID 27090093 DOI: 10.1038/Srep24544 |
0.505 |
|
| 2016 |
Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons. Nature Neuroscience. PMID 26878672 DOI: 10.1038/Nn.4245 |
0.708 |
|
| 2016 |
Labonté B, Maussion G, Yerko, Yang J, Golden S, Suderman M, Navarro L, Checknita D, Gigek C, Lopez J, Neve R, Russo S, Côté G, Meaney M, Mechawar N, et al. Speaker 4: Gustavo Turecki, Canada The International Journal of Neuropsychopharmacology. 19: 11-12. DOI: 10.1093/Ijnp/Pyw042.028 |
0.357 |
|
| 2016 |
Juster R, Seeman T, McEwen BS, Picard M, Mahar I, Mechawar N, Sindi S, Smith NG, Souza‐Talarico J, Sarnyai Z, Lanoix D, Plusquellec P, Ouellet‐Morin I, Lupien SJ. Social Inequalities and the Road to Allostatic Load: From Vulnerability to Resilience Development and Psychopathology. 1-54. DOI: 10.1002/9781119125556.Devpsy408 |
0.712 |
|
| 2015 |
Devorak J, Torres-Platas SG, Davoli MA, Prud'homme J, Turecki G, Mechawar N. Cellular and Molecular Inflammatory Profile of the Choroid Plexus in Depression and Suicide. Frontiers in Psychiatry. 6: 138. PMID 26539126 DOI: 10.3389/Fpsyt.2015.00138 |
0.786 |
|
| 2015 |
Lutz PE, Zhou Y, Labbe A, Mechawar N, Turecki G. Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26349406 DOI: 10.1016/J.Euroneuro.2015.08.015 |
0.552 |
|
| 2015 |
Maheu ME, Devorak J, Freibauer A, Davoli MA, Turecki G, Mechawar N. Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides. Frontiers in Neuroanatomy. 9: 74. PMID 26082689 DOI: 10.3389/Fnana.2015.00074 |
0.81 |
|
| 2015 |
Torres-Platas SG, Nagy C, Wakid M, Turecki G, Mechawar N. Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides. Molecular Psychiatry. PMID 26033239 DOI: 10.1038/Mp.2015.65 |
0.825 |
|
| 2015 |
Nagy C, Maheu M, Lopez JP, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G. Effects of postmortem interval on biomolecule integrity in the brain. Journal of Neuropathology and Experimental Neurology. 74: 459-69. PMID 25868148 DOI: 10.1097/Nen.0000000000000190 |
0.795 |
|
| 2015 |
Albuquerque MS, Mahar I, Davoli MA, Chabot JG, Mechawar N, Quirion R, Krantic S. Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease. Frontiers in Aging Neuroscience. 7: 30. PMID 25852545 DOI: 10.3389/Fnagi.2015.00030 |
0.77 |
|
| 2015 |
Vigneault É, Poirel O, Riad M, Prud'homme J, Dumas S, Turecki G, Fasano C, Mechawar N, El Mestikawy S. Distribution of vesicular glutamate transporters in the human brain. Frontiers in Neuroanatomy. 9: 23. PMID 25798091 DOI: 10.3389/Fnana.2015.00023 |
0.52 |
|
| 2015 |
Maheu M, Lopez JP, Crapper L, Davoli MA, Turecki G, Mechawar N. MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression. Translational Psychiatry. 5: e511. PMID 25689572 DOI: 10.1038/Tp.2015.11 |
0.802 |
|
| 2015 |
Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G. Astrocytic abnormalities and global DNA methylation patterns in depression and suicide. Molecular Psychiatry. 20: 320-8. PMID 24662927 DOI: 10.1038/Mp.2014.21 |
0.571 |
|
| 2015 |
Al-Hertani W, Mechawar N, Ernst C. MG-124 The investicate project: Identification of new variation, establishment of stem cells, and tissue collection advancing treatment efforts Journal of Medical Genetics. 52: A9.2-A9. DOI: 10.1136/Jmedgenet-2015-103578.24 |
0.304 |
|
| 2014 |
Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ, Mill J. Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biology. 15: 483. PMID 25347937 DOI: 10.1186/S13059-014-0483-2 |
0.493 |
|
| 2014 |
Lopez JP, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E, El Mestikawy S, Mechawar N, Pavlidis P, Turecki G. miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. Nature Medicine. 20: 764-8. PMID 24908571 DOI: 10.1038/Nm.3582 |
0.542 |
|
| 2014 |
Torres-Platas SG, Cruceanu C, Chen GG, Turecki G, Mechawar N. Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides. Brain, Behavior, and Immunity. 42: 50-9. PMID 24858659 DOI: 10.1016/J.Bbi.2014.05.007 |
0.798 |
|
| 2014 |
Maussion G, Yang J, Suderman M, Diallo A, Nagy C, Arnovitz M, Mechawar N, Turecki G. Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1061-70. PMID 24802768 DOI: 10.4161/Epi.29068 |
0.511 |
|
| 2014 |
Torres-Platas SG, Comeau S, Rachalski A, Bo GD, Cruceanu C, Turecki G, Giros B, Mechawar N. Morphometric characterization of microglial phenotypes in human cerebral cortex. Journal of Neuroinflammation. 11: 12. PMID 24447857 DOI: 10.1186/1742-2094-11-12 |
0.777 |
|
| 2014 |
Mahar I, Bambico FR, Mechawar N, Nobrega JN. Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects. Neuroscience and Biobehavioral Reviews. 38: 173-92. PMID 24300695 DOI: 10.1016/J.Neubiorev.2013.11.009 |
0.754 |
|
| 2014 |
Lopez JP, Fiori LM, Gross JA, Labonte B, Yerko V, Mechawar N, Turecki G. Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 23-32. PMID 24025154 DOI: 10.1017/S1461145713000941 |
0.49 |
|
| 2014 |
Silva PN, Furuya TK, Braga IL, Rasmussen LT, Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payão SL, Mill J, Smith MC. Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 38: 165-70. PMID 23948933 DOI: 10.3233/Jad-130428 |
0.47 |
|
| 2013 |
Parent MJ, Bedard MA, Aliaga A, Minuzzi L, Mechawar N, Soucy JP, Schirrmacher E, Kostikov A, Gauthier SG, Rosa-Neto P. Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography. International Journal of Molecular Imaging. 2013: 205045. PMID 24324884 DOI: 10.1155/2013/205045 |
0.308 |
|
| 2013 |
Labonté B, Suderman M, Maussion G, Lopez JP, Navarro-Sánchez L, Yerko V, Mechawar N, Szyf M, Meaney MJ, Turecki G. Genome-wide methylation changes in the brains of suicide completers. The American Journal of Psychiatry. 170: 511-20. PMID 23511308 DOI: 10.1176/Appi.Ajp.2012.12050627 |
0.506 |
|
| 2013 |
Freemantle E, Chen GG, Cruceanu C, Mechawar N, Turecki G. Analysis of oxysterols and cholesterol in prefrontal cortex of suicides. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1241-9. PMID 23369504 DOI: 10.1017/S1461145712001587 |
0.831 |
|
| 2013 |
Morales-Medina JC, Juarez I, Venancio-García E, Cabrera SN, Menard C, Yu W, Flores G, Mechawar N, Quirion R. Impaired structural hippocampal plasticity is associated with emotional and memory deficits in the olfactory bulbectomized rat. Neuroscience. 236: 233-43. PMID 23357118 DOI: 10.1016/J.Neuroscience.2013.01.037 |
0.807 |
|
| 2013 |
Maheu ME, Davoli MA, Turecki G, Mechawar N. Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide. Journal of Psychiatric Research. 47: 384-90. PMID 23260340 DOI: 10.1016/J.Jpsychires.2012.11.013 |
0.824 |
|
| 2013 |
Freemantle E, Mechawar N, Turecki G. Cholesterol and phospholipids in frontal cortex and synaptosomes of suicide completers: relationship with endosomal lipid trafficking genes. Journal of Psychiatric Research. 47: 272-9. PMID 23164340 DOI: 10.1016/J.Jpsychires.2012.10.019 |
0.809 |
|
| 2013 |
Silva PN, Furuya TK, Sampaio Braga I, Rasmussen LT, de Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payão SL, Mill J, Smith MC. CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 33: 349-55. PMID 22954668 DOI: 10.3233/Jad-2012-121192 |
0.506 |
|
| 2012 |
Freemantle E, Lalovic A, Mechawar N, Turecki G. Age and haplotype variations within FADS1 interact and associate with alterations in fatty acid composition in human male cortical brain tissue. Plos One. 7: e42696. PMID 22900039 DOI: 10.1371/Journal.Pone.0042696 |
0.794 |
|
| 2012 |
Furuya TK, da Silva PN, Payão SL, Rasmussen LT, de Labio RW, Bertolucci PH, Braga IL, Chen ES, Turecki G, Mechawar N, Mill J, de Arruda Cardoso Smith M. SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer's Disease. Neurochemistry International. 61: 973-5. PMID 22836009 DOI: 10.1016/J.Neuint.2012.07.014 |
0.475 |
|
| 2012 |
Maussion G, Yang J, Yerko V, Barker P, Mechawar N, Ernst C, Turecki G. Regulation of a truncated form of tropomyosin-related kinase B (TrkB) by Hsa-miR-185* in frontal cortex of suicide completers. Plos One. 7: e39301. PMID 22802923 DOI: 10.1371/Journal.Pone.0039301 |
0.453 |
|
| 2012 |
Labonté B, Suderman M, Maussion G, Navaro L, Yerko V, Mahar I, Bureau A, Mechawar N, Szyf M, Meaney MJ, Turecki G. Genome-wide epigenetic regulation by early-life trauma. Archives of General Psychiatry. 69: 722-31. PMID 22752237 DOI: 10.1001/Archgenpsychiatry.2011.2287 |
0.762 |
|
| 2012 |
Furuya TK, Silva PN, Payão SL, Bertolucci PH, Rasmussen LT, De Labio RW, Braga IL, Chen ES, Turecki G, Mechawar N, Mill J, Smith MA. Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients. Neuroscience. 220: 41-6. PMID 22732502 DOI: 10.1016/J.Neuroscience.2012.06.035 |
0.502 |
|
| 2012 |
Mahar I, Bagot RC, Davoli MA, Miksys S, Tyndale RF, Walker CD, Maheu M, Huang SH, Wong TP, Mechawar N. Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeeding. Plos One. 7: e37219. PMID 22615944 DOI: 10.1371/Journal.Pone.0037219 |
0.758 |
|
| 2012 |
Labonte B, Yerko V, Gross J, Mechawar N, Meaney MJ, Szyf M, Turecki G. Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse. Biological Psychiatry. 72: 41-8. PMID 22444201 DOI: 10.1016/J.Biopsych.2012.01.034 |
0.499 |
|
| 2012 |
Krantic S, Isorce N, Mechawar N, Davoli MA, Vignault E, Albuquerque M, Chabot JG, Moyse E, Chauvin JP, Aubert I, McLaurin J, Quirion R. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. Journal of Alzheimer's Disease : Jad. 29: 293-308. PMID 22232004 DOI: 10.3233/Jad-2011-110830 |
0.641 |
|
| 2012 |
Turecki G, Ernst C, Jollant F, Labonté B, Mechawar N. The neurodevelopmental origins of suicidal behavior. Trends in Neurosciences. 35: 14-23. PMID 22177979 DOI: 10.1016/J.Tins.2011.11.008 |
0.479 |
|
| 2012 |
Yu W, Mechawar N, Krantic S, Chabot J, Quirion R. Upregulation of astrocytic α7 nicotinic receptors in Alzheimer's disease brain- possible relevant to amyloid pathology Molecular Neurodegeneration. 7: O7. DOI: 10.1186/1750-1326-7-S1-O7 |
0.445 |
|
| 2011 |
Mahar I, Tan S, Davoli MA, Dominguez-Lopez S, Qiang C, Rachalski A, Turecki G, Mechawar N. Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects. Plos One. 6: e26610. PMID 22028923 DOI: 10.1371/Journal.Pone.0026610 |
0.794 |
|
| 2011 |
Yu W, Mechawar N, Krantic S, Quirion R. α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling. Journal of Neurochemistry. 119: 848-58. PMID 21884524 DOI: 10.1111/J.1471-4159.2011.07466.X |
0.43 |
|
| 2011 |
Torres-Platas SG, Hercher C, Davoli MA, Maussion G, Labonté B, Turecki G, Mechawar N. Astrocytic hypertrophy in anterior cingulate white matter of depressed suicides. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2650-8. PMID 21814185 DOI: 10.1038/Npp.2011.154 |
0.816 |
|
| 2011 |
Yu W, Gubkina O, Mechawar N, Elwell D, Quirion R, Krantic S. Expression of apoptosis-inducing factor (AIF) in the aged rat brain. Neurobiology of Aging. 32: 179-80. PMID 19251341 DOI: 10.1016/J.Neurobiolaging.2009.01.010 |
0.525 |
|
| 2010 |
Yu W, Mechawar N, Krantic S, Quirion R. Evidence for the involvement of apoptosis-inducing factor-mediated caspase-independent neuronal death in Alzheimer disease. The American Journal of Pathology. 176: 2209-18. PMID 20228227 DOI: 10.2353/Ajpath.2010.090496 |
0.492 |
|
| 2010 |
Chen GG, Fiori LM, Moquin L, Gratton A, Mamer O, Mechawar N, Turecki G. Evidence of altered polyamine concentrations in cerebral cortex of suicide completers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1477-84. PMID 20200507 DOI: 10.1038/Npp.2010.17 |
0.587 |
|
| 2010 |
Hercher C, Canetti L, Turecki G, Mechawar N. Anterior cingulate pyramidal neurons display altered dendritic branching in depressed suicides. Journal of Psychiatric Research. 44: 286-93. PMID 19765721 DOI: 10.1016/J.Jpsychires.2009.08.011 |
0.815 |
|
| 2010 |
Yu W, Krantic S, Mechawar N, Quirion R. P2-287: Nicotine prevents β-amyloid-induced apoptosis by inhibiting mitochondrial death pathway: A role for α7 nicotinic receptor and phosphatidylinositol 3-kinase (PI3K) Alzheimer's & Dementia. 6: S398-S398. DOI: 10.1016/J.Jalz.2010.05.1337 |
0.401 |
|
| 2009 |
Ernst C, Mechawar N, Turecki G. Suicide neurobiology. Progress in Neurobiology. 89: 315-33. PMID 19766697 DOI: 10.1016/j.pneurobio.2009.09.001 |
0.435 |
|
| 2009 |
Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. Plos One. 4: e6585. PMID 19668376 DOI: 10.1371/Journal.Pone.0006585 |
0.593 |
|
| 2009 |
Hercher C, Parent M, Flores C, Canetti L, Turecki G, Mechawar N. Alcohol dependence-related increase of glial cell density in the anterior cingulate cortex of suicide completers. Journal of Psychiatry & Neuroscience : Jpn. 34: 281-8. PMID 19568479 |
0.821 |
|
| 2009 |
Fiori LM, Mechawar N, Turecki G. Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completers. Biological Psychiatry. 66: 460-7. PMID 19446796 DOI: 10.1016/J.Biopsych.2009.04.002 |
0.47 |
|
| 2009 |
Hercher C, Turecki G, Mechawar N. Through the looking glass: examining neuroanatomical evidence for cellular alterations in major depression. Journal of Psychiatric Research. 43: 947-61. PMID 19233384 DOI: 10.1016/J.Jpsychires.2009.01.006 |
0.834 |
|
| 2007 |
Mechawar N, Lacoste B, Yu WF, Srivastava LK, Quirion R. Developmental profile of neuregulin receptor ErbB4 in postnatal rat cerebral cortex and hippocampus. Neuroscience. 148: 126-39. PMID 17630218 DOI: 10.1016/J.Neuroscience.2007.04.066 |
0.72 |
|
| 2007 |
Moser N, Mechawar N, Jones I, Gochberg-Sarver A, Orr-Urtreger A, Plomann M, Salas R, Molles B, Marubio L, Roth U, Maskos U, Winzer-Serhan U, Bourgeois JP, Le Sourd AM, De Biasi M, et al. Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures. Journal of Neurochemistry. 102: 479-92. PMID 17419810 DOI: 10.1111/J.1471-4159.2007.04498.X |
0.431 |
|
| 2007 |
Krantic S, Mechawar N, Reix S, Quirion R. Apoptosis-inducing factor: a matter of neuron life and death. Progress in Neurobiology. 81: 179-96. PMID 17267093 DOI: 10.1016/J.Pneurobio.2006.12.002 |
0.458 |
|
| 2007 |
Reix S, Mechawar N, Susin SA, Quirion R, Krantic S. Expression of cortical and hippocampal apoptosis-inducing factor (AIF) in aging and Alzheimer's disease. Neurobiology of Aging. 28: 351-6. PMID 16504343 DOI: 10.1016/J.Neurobiolaging.2006.01.003 |
0.474 |
|
| 2005 |
Krantic S, Mechawar N, Reix S, Quirion R. Molecular basis of programmed cell death involved in neurodegeneration. Trends in Neurosciences. 28: 670-6. PMID 16216345 DOI: 10.1016/J.Tins.2005.09.011 |
0.468 |
|
| 2004 |
Mechawar N, Saghatelyan A, Grailhe R, Scoriels L, Gheusi G, Gabellec MM, Lledo PM, Changeux JP. Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proceedings of the National Academy of Sciences of the United States of America. 101: 9822-6. PMID 15210938 DOI: 10.1073/Pnas.0403361101 |
0.47 |
|
| 2004 |
Descarries L, Mechawar N, Aznavour N, Watkins KC. Structural determinants of the roles of acetylcholine in cerebral cortex. Progress in Brain Research. 145: 45-58. PMID 14650905 DOI: 10.1016/S0079-6123(03)45002-4 |
0.591 |
|
| 2003 |
Aznavour N, Mechawar N, Watkins KC, Descarries L. Fine structural features of the acetylcholine innervation in the developing neostriatum of rat. The Journal of Comparative Neurology. 460: 280-91. PMID 12687691 DOI: 10.1002/Cne.10660 |
0.581 |
|
| 2002 |
Aznavour N, Mechawar N, Descarries L. Comparative analysis of cholinergic innervation in the dorsal hippocampus of adult mouse and rat: a quantitative immunocytochemical study. Hippocampus. 12: 206-17. PMID 12000119 DOI: 10.1002/Hipo.1108 |
0.561 |
|
| 2002 |
Pierret P, Mechawar N, Vallée A, Patel J, Priestley JV, Dunn RJ, Dower NA, Stone JC, Richardson PM. Presence of Ras guanyl nucleotide-releasing protein in striosomes of the mature and developing rat. Neuroscience. 111: 83-94. PMID 11955714 DOI: 10.1016/S0306-4522(01)00597-8 |
0.303 |
|
| 2002 |
Mechawar N, Watkins KC, Descarries L. Ultrastructural features of the acetylcholine innervation in the developing parietal cortex of rat. The Journal of Comparative Neurology. 443: 250-8. PMID 11807835 DOI: 10.1002/Cne.10114 |
0.582 |
|
| 2001 |
Mechawar N, Descarries L. The cholinergic innervation develops early and rapidly in the rat cerebral cortex: a quantitative immunocytochemical study. Neuroscience. 108: 555-67. PMID 11738494 DOI: 10.1016/S0306-4522(01)00389-X |
0.595 |
|
| 2001 |
Pierret P, Vallée A, Mechawar N, Dower NA, Stone JC, Richardson PM, Dunn RJ. Cellular and subcellular localization of Ras guanyl nucleotide-releasing protein in the rat hippocampus. Neuroscience. 108: 381-90. PMID 11738253 DOI: 10.1016/S0306-4522(01)00429-8 |
0.325 |
|
| 2000 |
Descarries L, Mechawar N. Ultrastructural evidence for diffuse transmission by monoamine and acetylcholine neurons of the central nervous system. Progress in Brain Research. 125: 27-47. PMID 11098652 DOI: 10.1016/S0079-6123(00)25005-X |
0.579 |
|
| 2000 |
Mechawar N, Cozzari C, Descarries L. Cholinergic innervation in adult rat cerebral cortex: a quantitative immunocytochemical description. The Journal of Comparative Neurology. 428: 305-18. PMID 11064369 DOI: 10.1002/1096-9861(20001211)428:2<305::Aid-Cne9>3.0.Co;2-Y |
0.577 |
|
| 1998 |
Mansour-Robaey S, Mechawar N, Radja F, Beaulieu C, Descarries L. Quantified distribution of serotonin transporter and receptors during the postnatal development of the rat barrel field cortex. Brain Research. Developmental Brain Research. 107: 159-63. PMID 9602106 DOI: 10.1016/S0165-3806(98)00016-9 |
0.563 |
|
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