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Antoine E. Karnoub, Ph.D. - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Ras and Rho GTPases, Their Modulators and Effectors
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tu Z, Schmoellerl J, Mariani O, Zheng Y, Hu Y, Vincent-Salomon A, Karnoub AE. The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer. Npj Breast Cancer. 7: 69. PMID 34059683 DOI: 10.1038/s41523-021-00259-z  0.326
2019 Tu Z, Schmöllerl J, Cuiffo BG, Karnoub AE. Microenvironmental regulation of long non-coding RNA LINC01133 promotes cancer-stem-cell-like phenotypic traits in triple-negative breast cancers. Stem Cells (Dayton, Ohio). PMID 31283068 DOI: 10.1002/Stem.3055  0.411
2017 Karnoub AE, VanHook AM. Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer. Science Signaling. 10. PMID 28223415 DOI: 10.1126/Scisignal.Aam8855  0.41
2017 Thomas C, Henry W, Cuiffo BG, Collmann AY, Marangoni E, Benhamo V, Bhasin MK, Fan C, Fuhrmann L, Baldwin AS, Perou C, Vincent-Salomon A, Toker A, Karnoub AE. Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Science Signaling. 10. PMID 28223411 DOI: 10.1126/Scisignal.Aah4674  0.444
2016 Cuiffo BG, Karnoub AE. Silencing FOXP2 in breast cancer cells promotes cancer stem cell traits and metastasis. Molecular & Cellular Oncology. 3: e1019022. PMID 27314063 DOI: 10.1080/23723556.2015.1019022  0.373
2015 Cuiffo BG, Campagne A, Bell GW, Lembo A, Orso F, Lien E, Bhasin MK, Raimo M, Hanson SE, Marusyk A, Hematti P, Polyak K, Mariani O, Volinia S, Vincent-Salomon A, ... ... Karnoub AE, et al. Abstract P1-07-02: Mesenchymal stem cell regulated microRNAs converge on the speech gene FOXP2 and regulate breast cancer metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-02  0.361
2014 Cuiffo BG, Campagne A, Bell GW, Lembo A, Orso F, Lien EC, Bhasin MK, Raimo M, Hanson SE, Marusyk A, El-Ashry D, Hematti P, Polyak K, Mechta-Grigoriou F, Mariani O, ... ... Karnoub AE, et al. MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis. Cell Stem Cell. 15: 762-74. PMID 25515522 DOI: 10.1016/J.Stem.2014.10.001  0.382
2014 Cuiffo B, Campagne A, Bell GW, Lien E, Bhasin MK, Mariani O, Vincent-Salomon A, Karnoub A. Abstract 173: Tumor proximal mesenchymal stem cells initiate a pro-metastatic microRNA regulatory network which acts via convergent targeting of the speech-associated transcriptional repressor FOXP2 Cancer Research. 74: 173-173. DOI: 10.1158/1538-7445.Am2014-173  0.391
2013 Thomas C, Karnoub AE. Lysyl oxidase at the crossroads of mesenchymal stem cells and epithelial-mesenchymal transition. Oncotarget. 4: 376-7. PMID 23530115 DOI: 10.18632/Oncotarget.919  0.431
2012 El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proceedings of the National Academy of Sciences of the United States of America. 109: 17460-5. PMID 23033492 DOI: 10.1073/Pnas.1206653109  0.416
2012 Cuiffo BG, Karnoub AE. Mesenchymal stem cells in tumor development: emerging roles and concepts. Cell Adhesion & Migration. 6: 220-30. PMID 22863739 DOI: 10.4161/Cam.20875  0.35
2010 El-Haibi CP, Karnoub AE. Mesenchymal stem cells in the pathogenesis and therapy of breast cancer. Journal of Mammary Gland Biology and Neoplasia. 15: 399-409. PMID 21170761 DOI: 10.1007/S10911-010-9196-7  0.367
2008 Karnoub AE, Weinberg RA. Ras oncogenes: split personalities. Nature Reviews. Molecular Cell Biology. 9: 517-31. PMID 18568040 DOI: 10.1038/Nrm2438  0.311
2007 Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 449: 557-63. PMID 17914389 DOI: 10.1038/Nature06188  0.376
2007 Ince TA, Richardson AL, Bell GW, Saitoh M, Godar S, Karnoub AE, Iglehart JD, Weinberg RA. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 12: 160-70. PMID 17692807 DOI: 10.1016/J.Ccr.2007.06.013  0.352
2007 Yohe ME, Rossman KL, Gardner OS, Karnoub AE, Snyder JT, Gershburg S, Graves LM, Der CJ, Sondek J. Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif. The Journal of Biological Chemistry. 282: 13813-23. PMID 17337446 DOI: 10.1074/Jbc.M700185200  0.388
2006 Karnoub AE, Weinberg RA. Chemokine networks and breast cancer metastasis. Breast Disease. 26: 75-85. PMID 17473367 DOI: 10.3233/Bd-2007-26107  0.396
2004 Palmby TR, Abe K, Karnoub AE, Der CJ. Vav transformation requires activation of multiple GTPases and regulation of gene expression. Molecular Cancer Research : McR. 2: 702-11. PMID 15634759  0.361
2004 Singh A, Karnoub AE, Palmby TR, Lengyel E, Sondek J, Der CJ. Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene. 23: 9369-80. PMID 15516977 DOI: 10.1038/Sj.Onc.1208182  0.497
2004 Karnoub AE, Symons M, Campbell SL, Der CJ. Molecular basis for Rho GTPase signaling specificity. Breast Cancer Research and Treatment. 84: 61-71. PMID 14999155 DOI: 10.1023/B:Brea.0000018427.84929.5C  0.57
2003 Pruitt WM, Karnoub AE, Rakauskas AC, Guipponi M, Antonarakis SE, Kurakin A, Kay BK, Sondek J, Siderovski DP, Der CJ. Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling. Biochimica Et Biophysica Acta. 1640: 61-8. PMID 12676355 DOI: 10.1016/S0167-4889(03)00002-8  0.371
2003 Fuentes EJ, Karnoub AE, Booden MA, Der CJ, Campbell SL. Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation. The Journal of Biological Chemistry. 278: 21188-96. PMID 12637530 DOI: 10.1074/Jbc.M211792200  0.562
2002 Wennerberg K, Ellerbroek SM, Liu RY, Karnoub AE, Burridge K, Der CJ. RhoG signals in parallel with Rac1 and Cdc42. The Journal of Biological Chemistry. 277: 47810-7. PMID 12376551 DOI: 10.1074/Jbc.M203816200  0.445
2002 Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT, Der CJ, Counter CM. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes & Development. 16: 2045-57. PMID 12183360 DOI: 10.1101/Gad.993902  0.337
2002 Thapar R, Karnoub AE, Campbell SL. Structural and biophysical insights into the role of the insert region in Rac1 function. Biochemistry. 41: 3875-83. PMID 11900529 DOI: 10.1021/Bi0120087  0.614
2002 Lambert JM, Karnoub AE, Graves LM, Campbell SL, Der CJ. Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation. The Journal of Biological Chemistry. 277: 4770-7. PMID 11713255 DOI: 10.1074/Jbc.M109379200  0.534
2001 Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors. Nature Structural Biology. 8: 1037-41. PMID 11685227 DOI: 10.1038/Nsb719  0.558
2001 Karnoub AE, Der CJ, Campbell SL. The insert region of Rac1 is essential for membrane ruffling but not cellular transformation. Molecular and Cellular Biology. 21: 2847-57. PMID 11283263 DOI: 10.1128/Mcb.21.8.2847-2857.2001  0.578
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