Jake G. Hoekstra, Ph.D. - Publications

Affiliations: 
Pathology University of Washington, Seattle, Seattle, WA 
Area:
Neurodegeneration

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Samstag CL, Hoekstra JG, Huang CH, Chaisson MJ, Youle RJ, Kennedy SR, Pallanck LJ. Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ. Plos Genetics. 14: e1007805. PMID 30452458 DOI: 10.1371/Journal.Pgen.1007805  0.312
2016 Hoekstra JG, Hipp MJ, Montine TJ, Kennedy SR. Mitochondrial DNA Mutations Increase in Early Stage Alzheimer's Disease and are Inconsistent with Oxidative Damage. Annals of Neurology. PMID 27315116 DOI: 10.1002/Ana.24709  0.481
2016 Huber BR, Meabon JS, Hoffer ZS, Zhang J, Hoekstra JG, Pagulayan KF, McMillan PJ, Mayer CL, Banks WA, Kraemer BC, Raskind MA, McGavern DB, Peskind ER, Cook DG. Blast Exposure Causes Dynamic Microglial/Macrophage Responses and Microdomains of Brain Microvessel Dysfunction. Neuroscience. PMID 26777891 DOI: 10.1016/J.Neuroscience.2016.01.022  0.302
2015 Pickrell AM, Huang CH, Kennedy SR, Ordureau A, Sideris DP, Hoekstra JG, Harper JW, Youle RJ. Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress. Neuron. 87: 371-81. PMID 26182419 DOI: 10.1016/J.Neuron.2015.06.034  0.466
2015 Cook TJ, Hoekstra JG, Eaton DL, Zhang J. Mortalin is expressed by astrocytes and decreased in the midbrain of Parkinson's disease patients. Brain Pathology (Zurich, Switzerland). PMID 26095919 DOI: 10.1111/Bpa.12274  0.654
2015 Jiang T, Hoekstra J, Heng X, Kang W, Ding J, Liu J, Chen S, Zhang J. P2X7 receptor is critical in α-synuclein-mediated microglial NADPH oxidase activation. Neurobiology of Aging. 36: 2304-18. PMID 25983062 DOI: 10.1016/J.Neurobiolaging.2015.03.015  0.426
2015 Hoekstra JG, Cook TJ, Stewart T, Mattison H, Dreisbach MT, Hoffer ZS, Zhang J. Astrocytic dynamin-like protein 1 regulates neuronal protection against excitotoxicity in Parkinson disease. The American Journal of Pathology. 185: 536-49. PMID 25482923 DOI: 10.1016/J.Ajpath.2014.10.022  0.625
2014 Jin J, Zhang J, Cook TJ, Hoekstra JG. Mortalin in neurological diseases Mortalin Biology: Life, Stress and Death. 2147483647: 139-158. DOI: 10.1007/978-94-007-3027-4_9  0.583
2013 Wang J, Hoekstra JG, Zuo C, Cook TJ, Zhang J. Biomarkers of Parkinson's disease: current status and future perspectives. Drug Discovery Today. 18: 155-62. PMID 22982303 DOI: 10.1016/J.Drudis.2012.09.001  0.619
2011 Hoekstra JG, Montine KS, Zhang J, Montine TJ. Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease. Alzheimer's Research & Therapy. 3: 21. PMID 21722346 DOI: 10.1186/Alzrt83  0.602
2008 Caudle WM, Pan S, Shi M, Quinn T, Hoekstra J, Beyer RP, Montine TJ, Zhang J. Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease. Proteomics. Clinical Applications. 2: 1484-97. PMID 21136796 DOI: 10.1002/Prca.200800043  0.616
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