| Year |
Citation |
Score |
| 2021 |
Jana S, Deo R, Hough RP, Liu Y, Horn JL, Wright JL, Lam HM, Webster KR, Chiang GG, Sonenberg N, Hsieh AC. mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformation. Jci Insight. 6. PMID 34032633 DOI: 10.1172/jci.insight.144920 |
0.342 |
|
| 2018 |
Reich SH, Sprengeler PA, Chiang GG, Appleman JR, Chen J, Clarine J, Eam B, Ernst JT, Han Q, Goel VK, Han EZ, Huang V, Hung IN, Jemison A, Jessen KA, et al. Structure-based Design of Pyridone-aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. Journal of Medicinal Chemistry. PMID 29526098 DOI: 10.1021/Acs.Jmedchem.7B01795 |
0.334 |
|
| 2015 |
Webster KR, Goel VK, Hung IN, Parker GS, Staunton J, Neal M, Molter J, Chiang GG, Jessen KA, Wegerski CJ, Sperry S, Huang V, Chen J, Thompson PA, Appleman JR, et al. eFT508, a Potent and Selective Mitogen-Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 Inhibitor, Is Efficacious in Preclinical Models of Diffuse Large B-Cell Lymphoma (DLBCL) Blood. 126: 1554-1554. DOI: 10.1182/Blood.V126.23.1554.1554 |
0.355 |
|
| 2010 |
Barile E, De SK, Carlson CB, Chen V, Knutzen C, Riel-Mehan M, Yang L, Dahl R, Chiang G, Pellecchia M. Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway. Journal of Medicinal Chemistry. 53: 8368-75. PMID 21062009 DOI: 10.1021/Jm100825H |
0.336 |
|
| 2005 |
Zhang YW, Otterness DM, Chiang GG, Xie W, Liu YC, Mercurio F, Abraham RT. Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Molecular Cell. 19: 607-18. PMID 16137618 DOI: 10.1016/j.molcel.2005.07.019 |
0.386 |
|
| 2005 |
Chiang GG, Abraham RT. Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase. The Journal of Biological Chemistry. 280: 25485-90. PMID 15899889 DOI: 10.1074/jbc.M501707200 |
0.535 |
|
| 2004 |
Wipf P, Minion DJ, Halter RJ, Berggren MI, Ho CB, Chiang GG, Kirkpatrick L, Abraham R, Powis G. Synthesis and biological evaluation of synthetic viridins derived from C(20)-heteroalkylation of the steroidal PI-3-kinase inhibitor wortmannin. Organic & Biomolecular Chemistry. 2: 1911-20. PMID 15227545 DOI: 10.1039/B405431H |
0.413 |
|
| 2004 |
Chiang GG, Abraham RT. Determination of the catalytic activities of mTOR and other members of the phosphoinositide-3-kinase-related kinase family. Methods in Molecular Biology (Clifton, N.J.). 281: 125-41. PMID 15220525 DOI: 10.1385/1-59259-811-0:125 |
0.538 |
|
| 2003 |
Edinger AL, Linardic CM, Chiang GG, Thompson CB, Abraham RT. Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells. Cancer Research. 63: 8451-60. PMID 14679009 |
0.474 |
|
| 2001 |
Chiang GG, Sefton BM. Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase. The Journal of Biological Chemistry. 276: 23173-8. PMID 11294838 DOI: 10.1074/Jbc.M101219200 |
0.496 |
|
| 2000 |
Chiang GG, Sefton BM. Phosphorylation of a Src kinase at the autophosphorylation site in the absence of Src kinase activity. The Journal of Biological Chemistry. 275: 6055-8. PMID 10692391 DOI: 10.1074/Jbc.275.9.6055 |
0.489 |
|
| 1997 |
Baskaran R, Chiang GG, Mysliwiec T, Kruh GD, Wang JY. Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product. The Journal of Biological Chemistry. 272: 18905-9. PMID 9228069 DOI: 10.1074/jbc.272.30.18905 |
0.429 |
|
| 1996 |
Baskaran R, Chiang GG, Wang JY. Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II. Molecular and Cellular Biology. 16: 3361-9. PMID 8668151 |
0.339 |
|
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