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David M. Feldser, Ph.D. - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Telomeres and telomerase in chromosome maintenance and stability
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Acosta J, Li Q, Freeburg NF, Murali N, Indeglia A, Grothusen GP, Cicchini M, Mai H, Gladstein AC, Adler KM, Doerig KR, Li J, Ruiz-Torres M, Manning KL, Stanger BZ, ... ... Feldser DM, et al. p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism. Nature Communications. 14: 4403. PMID 37479684 DOI: 10.1038/s41467-023-40161-9  0.32
2021 Doan A, Arand J, Gong D, Drainas AP, Shue YT, Lee MC, Zhang S, Walter DM, Chaikovsky AC, Feldser DM, Vogel H, Dow LE, Skotheim JM, Sage J. RB depletion is required for the continuous growth of tumors initiated by loss of RB. Plos Genetics. 17: e1009941. PMID 34879057 DOI: 10.1371/journal.pgen.1009941  0.338
2021 Pierce SE, Granja JM, Corces MR, Brady JJ, Tsai MK, Pierce AB, Tang R, Chu P, Feldser DM, Chang HY, Bassik MC, Greenleaf WJ, Winslow MM. LKB1 inactivation modulates chromatin accessibility to drive metastatic progression. Nature Cell Biology. PMID 34341533 DOI: 10.1038/s41556-021-00728-4  0.334
2021 Sánchez-Rivera FJ, Ryan J, Soto-Feliciano YM, Clare Beytagh M, Xuan L, Feldser DM, Hemann MT, Zamudio J, Dimitrova N, Letai A, Jacks T. Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074758 DOI: 10.1073/pnas.2019740118  0.564
2020 Lin JH, Huffman AP, Wattenberg MM, Walter DM, Carpenter EL, Feldser DM, Beatty GL, Furth EE, Vonderheide RH. Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis. The Journal of Experimental Medicine. 217. PMID 32453421 DOI: 10.1084/Jem.20190673  0.368
2020 Kharbanda A, Walter DM, Gudiel AA, Schek N, Feldser DM, Witze ES. Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis. Science Signaling. 13. PMID 32127496 DOI: 10.1126/Scisignal.Aax2364  0.38
2019 Walter DM, Yates TJ, Ruiz-Torres M, Kim-Kiselak C, Gudiel AA, Deshpande C, Wang WZ, Cicchini M, Stokes KL, Tobias JW, Buza E, Feldser DM. RB constrains lineage fidelity and multiple stages of tumour progression and metastasis. Nature. PMID 31043741 DOI: 10.1038/S41586-019-1172-9  0.435
2019 Stokes KL, Cortez-Retamozo V, Acosta J, Lauderback B, Robles-Oteiza C, Cicchini M, Pittet MJ, Feldser DM. Natural killer cells limit the clearance of senescent lung adenocarcinoma cells. Oncogenesis. 8: 24. PMID 30936429 DOI: 10.1038/s41389-019-0133-3  0.309
2018 Acosta J, Wang W, Feldser DM. Off and back-on again: a tumor suppressor's tale. Oncogene. PMID 29540833 DOI: 10.1038/S41388-018-0186-3  0.36
2018 Yates T, Kim-Kiselak C, Wang W, Feldser DM. Abstract PR01: Modeling Rb loss and pathway reactivation in lung adenocarcinoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Pr01  0.431
2018 Perez-Oquendo MG, Feldser DM, Walter D. Abstract LB-195: Identifying cooperative effects of tumor suppressor gene mutations in lung adenocarcinoma using paired CRISPR-Cas9 Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-195  0.437
2017 Cicchini M, Buza EL, Sagal KM, Gudiel AA, Durham AC, Feldser DM. Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression. Cell Reports. 18: 1958-1969. PMID 28228261 DOI: 10.1016/J.Celrep.2017.01.069  0.373
2017 Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM. Systematic in vivo inactivation of chromatin regulating enzymes identifies Setd2 as a potent tumor suppressor in lung adenocarcinoma. Cancer Research. PMID 28202515 DOI: 10.1158/0008-5472.Can-16-2159  0.402
2016 Garg R, Kapoor V, Abba M, Feldser DM, Albelda SM, Kazanietz MG. Abstract 5164: Protein kinase C epsilon is a mediator of KRAS-driven lung tumorigenesis Cancer Research. 76: 5164-5164. DOI: 10.1158/1538-7445.Am2016-5164  0.433
2015 Robles-Oteiza C, Taylor S, Yates T, Cicchini M, Lauderback B, Cashman CR, Burds AA, Winslow MM, Jacks T, Feldser DM. Recombinase-based conditional and reversible gene regulation via XTR alleles. Nature Communications. 6: 8783. PMID 26537451 DOI: 10.1038/Ncomms9783  0.313
2015 Li Y, Park AI, Mou H, Colpan C, Bizhanova A, Akama-Garren E, Joshi N, Hendrickson EA, Feldser D, Yin H, Anderson DG, Jacks T, Weng Z, Xue W. A versatile reporter system for CRISPR-mediated chromosomal rearrangements. Genome Biology. 16: 111. PMID 26018130 DOI: 10.1186/S13059-015-0680-7  0.348
2014 Sánchez-Rivera FJ, Ryan J, Soto-Feliciano YM, Feldser DM, Hemann MT, Letai A, Jacks T. Abstract 2961: The level of mitochondrial apoptotic priming determines cell fate upon p53 restoration Cancer Research. 74: 2961-2961. DOI: 10.1158/1538-7445.Am2014-2961  0.615
2012 Sánchez-Rivera FJ, Feldser DM, Doench J, Bhutkar A, Meacham CE, Root DE, Hemann MT, Jacks T. Abstract 2957: Uncovering tumor-specific components of the p53 pathway using mouse models and RNAi Cancer Research. 72: 2957-2957. DOI: 10.1158/1538-7445.Am2012-2957  0.622
2011 Xue W, Meylan E, Oliver TG, Feldser DM, Winslow MM, Bronson R, Jacks T. Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. Cancer Discovery. 1: 236-47. PMID 21874163 DOI: 10.1158/2159-8290.Cd-11-0073  0.391
2011 Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, et al. Suppression of lung adenocarcinoma progression by Nkx2-1. Nature. 473: 101-4. PMID 21471965 DOI: 10.1038/Nature09881  0.442
2010 Feldser DM, Kostova KK, Winslow MM, Taylor SE, Cashman C, Whittaker CA, Sanchez-Rivera FJ, Resnick R, Bronson R, Hemann MT, Jacks T. Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature. 468: 572-5. PMID 21107428 DOI: 10.1038/Nature09535  0.623
2010 Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 142: 409-19. PMID 20673990 DOI: 10.1016/J.Cell.2010.06.040  0.341
2009 Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, Jacks T. Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature. 462: 104-7. PMID 19847165 DOI: 10.1038/Nature08462  0.383
2009 Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 458: 223-7. PMID 19182780 DOI: 10.1038/Nature07672  0.313
2008 Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 134: 62-73. PMID 18614011 DOI: 10.1016/J.Cell.2008.06.006  0.336
2007 Feldser DM, Greider CW. Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell. 11: 461-9. PMID 17433785 DOI: 10.1016/J.Ccr.2007.02.026  0.641
2006 Feldser D, Strong MA, Greider CW. Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres. Proceedings of the National Academy of Sciences of the United States of America. 103: 2249-51. PMID 16467146 DOI: 10.1073/Pnas.0511143103  0.636
2005 Hao LY, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW. Short telomeres, even in the presence of telomerase, limit tissue renewal capacity. Cell. 123: 1121-31. PMID 16360040 DOI: 10.1016/J.Cell.2005.11.020  0.684
2003 Feldser DM, Hackett JA, Greider CW. Telomere dysfunction and the initiation of genome instability. Nature Reviews. Cancer. 3: 623-7. PMID 12894250 DOI: 10.1038/Nrc1142  0.678
2001 Semenza GL, Artemov D, Bedi A, Bhujwalla Z, Chiles K, Feldser D, Laughner E, Ravi R, Simons J, Taghavi P, Zhong H. 'The metabolism of tumours': 70 years later Novartis Foundation Symposium. 240: 251-260. PMID 11727934 DOI: 10.1002/0470868716.Ch17  0.373
2001 Feldser DM, Kern SE. Oncogenic levels of mitogen-activated protein kinase (MAPK) signaling of the dinucleotide KRAS2 mutations G12F and GG12-13VC. Human Mutation. 18: 357. PMID 11668624 DOI: 10.1002/Humu.1202  0.368
2001 Hackett JA, Feldser DM, Greider CW. Telomere dysfunction increases mutation rate and genomic instability. Cell. 106: 275-86. PMID 11509177 DOI: 10.1016/S0092-8674(01)00457-3  0.687
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