Brian F. Pachkowski, Ph.D. - Publications

Affiliations: 
Environmental Sciences & Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Pachkowski B, Nakamura J. A neutral glyoxal gel electrophoresis method for the detection and semi-quantitation of DNA single-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 1054: 133-43. PMID 23913289 DOI: 10.1007/978-1-62703-565-1_8  0.65
2011 Pachkowski BF, Guyton KZ, Sonawane B. DNA repair during in utero development: a review of the current state of knowledge, research needs, and potential application in risk assessment. Mutation Research. 728: 35-46. PMID 21679774 DOI: 10.1016/j.mrrev.2011.05.003  0.514
2010 Luke AM, Chastain PD, Pachkowski BF, Afonin V, Takeda S, Kaufman DG, Swenberg JA, Nakamura J. Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. Mutation Research. 694: 65-71. PMID 20851134 DOI: 10.1016/J.Mrfmmm.2010.08.008  0.637
2010 Boysen G, Collins LB, Liao S, Luke AM, Pachkowski BF, Watters JL, Swenberg JA. Analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine by ultra high pressure liquid chromatography-heat assisted electrospray ionization-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 375-80. PMID 20022307 DOI: 10.1016/J.Jchromb.2009.12.004  0.628
2009 Pachkowski BF, Tano K, Afonin V, Elder RH, Takeda S, Watanabe M, Swenberg JA, Nakamura J. Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS. Mutation Research. 671: 93-9. PMID 19778542 DOI: 10.1016/J.Mrfmmm.2009.09.006  0.627
2009 Boysen G, Pachkowski BF, Nakamura J, Swenberg JA. The formation and biological significance of N7-guanine adducts. Mutation Research. 678: 76-94. PMID 19465146 DOI: 10.1016/J.Mrgentox.2009.05.006  0.592
2006 Pachkowski BF, Winkel S, Kubota Y, Swenberg JA, Millikan RC, Nakamura J. XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Research. 66: 2860-8. PMID 16510609 DOI: 10.1158/0008-5472.Can-05-3388  0.51
2005 Rinne ML, He Y, Pachkowski BF, Nakamura J, Kelley MR. N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts. Nucleic Acids Research. 33: 2859-67. PMID 15905475 DOI: 10.1093/Nar/Gki601  0.557
2005 McDorman KS, Pachkowski BF, Nakamura J, Wolf DC, Swenberg JA. Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products. Chemico-Biological Interactions. 152: 107-17. PMID 15840384 DOI: 10.1016/J.Cbi.2005.02.003  0.653
2005 Jeong YC, Sangaiah R, Nakamura J, Pachkowski BF, Ranasinghe A, Gold A, Ball LM, Swenberg JA. Analysis of M1G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry. Chemical Research in Toxicology. 18: 51-60. PMID 15651849 DOI: 10.1021/Tx049853L  0.71
2004 Rusyn I, Asakura S, Pachkowski B, Bradford BU, Denissenko MF, Peters JM, Holland SM, Reddy JK, Cunningham ML, Swenberg JA. Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators. Cancer Research. 64: 1050-7. PMID 14871837 DOI: 10.1158/0008-5472.Can-03-3027  0.679
2003 Horton JK, Joyce-Gray DF, Pachkowski BF, Swenberg JA, Wilson SH. Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. Dna Repair. 2: 27-48. PMID 12509266 DOI: 10.1016/S1568-7864(02)00184-2  0.642
2002 Swenberg JA, Ham AJ, Koc H, La DK, Morinello EJ, Pachkowski BF, Ranasinghe A, Upton PB. Methods for measuring DNA adducts and abasic sites II: methods for measurement of DNA adducts. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit3.9. PMID 23045080 DOI: 10.1002/0471140856.Tx0309S12  0.67
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