| Year |
Citation |
Score |
| 2023 |
Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ. AP-1 signaling modulates cardiac fibroblast stress responses. Journal of Cell Science. PMID 37994565 DOI: 10.1242/jcs.261152 |
0.32 |
|
| 2023 |
Moon SY, de Campos PS, Matte BF, Placone JK, Zanella VLG, Martins MD, Lamers ML, Engler AJ. Cell contractility drives mechanical memory of oral squamous cell carcinoma. Molecular Biology of the Cell. mbcE22070266. PMID 37342880 DOI: 10.1091/mbc.E22-07-0266 |
0.734 |
|
| 2023 |
Mayner JM, Masutani EM, Demeester E, Kumar A, Macapugay G, Beri P, Lo Sardo V, Engler AJ. Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217122120. PMID 37276403 DOI: 10.1073/pnas.2217122120 |
0.812 |
|
| 2023 |
Atcha H, Choi YS, Chaudhuri O, Engler AJ. Getting physical: Material mechanics is an intrinsic cell cue. Cell Stem Cell. 30: 750-765. PMID 37267912 DOI: 10.1016/j.stem.2023.05.003 |
0.633 |
|
| 2022 |
Kirkland NJ, Skalak SH, Whitehead AJ, Hocker JD, Beri P, Vogler G, Hum B, Wang M, Lakatta EG, Ren B, Bodmer R, Engler AJ. Age-dependent Lamin changes induce cardiac dysfunction via dysregulation of cardiac transcriptional programs. Nature Aging. 3: 17-33. PMID 36845078 DOI: 10.1038/s43587-022-00323-8 |
0.787 |
|
| 2021 |
Whitehead AJ, Hocker JD, Ren B, Engler AJ. Improved epicardial cardiac fibroblast generation from iPSCs. Journal of Molecular and Cellular Cardiology. 164: 58-68. PMID 34826415 DOI: 10.1016/j.yjmcc.2021.11.011 |
0.357 |
|
| 2021 |
Teng EL, Masutani EM, Yeoman B, Fung J, Lian R, Ngo B, Kumar A, Placone JK, Lo Sardo V, Engler AJ. High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3. Apl Bioengineering. 5: 036102. PMID 34327295 DOI: 10.1063/5.0054639 |
0.752 |
|
| 2021 |
Yeoman B, Shatkin G, Beri P, Banisadr A, Katira P, Engler AJ. Adhesion strength and contractility enable metastatic cells to become adurotactic. Cell Reports. 34: 108816. PMID 33691109 DOI: 10.1016/j.celrep.2021.108816 |
0.83 |
|
| 2020 |
Banisadr A, Eick M, Beri P, Parisian AD, Yeoman B, Placone JK, Engler AJ, Furnari F. EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration. Journal of Cell Science. PMID 33243756 DOI: 10.1242/jcs.247189 |
0.812 |
|
| 2020 |
Fattet L, Jung HY, Matsumoto MW, Aubol BE, Kumar A, Adams JA, Chen AC, Sah RL, Engler AJ, Pasquale EB, Yang J. Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex. Developmental Cell. PMID 32574556 DOI: 10.1016/J.Devcel.2020.05.031 |
0.611 |
|
| 2020 |
Plunkett C, Kumar A, Yrastorza J, Hou YH, Placone JK, Grennan G, Engler AJ. H-Ras Transformation of Mammary Epithelial Cells Induces ERK-Mediated Spreading on Low Stiffness Matrix. Advanced Healthcare Materials. e1901366. PMID 31951109 DOI: 10.1002/Adhm.201901366 |
0.806 |
|
| 2019 |
Beri P, Popravko A, Yeoman B, Kumar A, Chen K, Hodzic E, Chiang A, Banisadr A, Placone JK, Carter H, Fraley SI, Katira P, Engler AJ. Cell adhesiveness serves as a biophysical marker for metastatic potential. Cancer Research. PMID 31857292 DOI: 10.1158/0008-5472.Can-19-1794 |
0.792 |
|
| 2019 |
Wong L, Kumar A, Gabela-Zuniga B, Chua J, Singh G, Happe CL, Engler AJ, Fan Y, McCloskey KE. Substrate Stiffness Directs Diverging Vascular Fates. Acta Biomaterialia. PMID 31326665 DOI: 10.1016/J.Actbio.2019.07.030 |
0.481 |
|
| 2019 |
Velez DO, Ranamukhaarachchi SK, Kumar A, Modi RN, Lim EW, Engler AJ, Metallo CM, Fraley SI. 3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 31251330 DOI: 10.1093/Intbio/Zyz019 |
0.661 |
|
| 2019 |
Kumar A, Thomas SK, Wong KC, Lo Sardo V, Cheah DS, Hou YH, Placone JK, Tenerelli KP, Ferguson WC, Torkamani A, Topol EJ, Baldwin KK, Engler AJ. Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes. Nature Biomedical Engineering. 3: 137-146. PMID 30911429 DOI: 10.1038/S41551-018-0344-5 |
0.789 |
|
| 2019 |
Teng EL, Engler AJ. Mechanical influences on Cardiovascular Differentiation and Disease Modeling. Experimental Cell Research. PMID 30794804 DOI: 10.1016/J.Yexcr.2019.02.019 |
0.403 |
|
| 2019 |
Ondeck MG, Kumar A, Placone JK, Plunkett CM, Matte BF, Wong KC, Fattet L, Yang J, Engler AJ. Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30755531 DOI: 10.1073/Pnas.1814204116 |
0.81 |
|
| 2019 |
Ranamukhaarachchi SK, Modi RN, Han A, Velez DO, Kumar A, Engler AJ, Fraley SI. Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis. Biomaterials Science. 7: 618-633. PMID 30515503 DOI: 10.1039/C8Bm01188E |
0.659 |
|
| 2018 |
Engler AJ, Discher DE. Rationally engineered advances in cancer research. Apl Bioengineering. 2: 031601. PMID 31069310 DOI: 10.1063/1.5056176 |
0.415 |
|
| 2018 |
Matte BF, Kumar A, Placone JK, Zanella VG, Martins MD, Engler AJ, Lamers ML. Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinoma. Journal of Cell Science. PMID 30559248 DOI: 10.1242/Jcs.224360 |
0.791 |
|
| 2018 |
Lo Sardo V, Chubukov P, Ferguson W, Kumar A, Teng EL, Duran M, Zhang L, Cost G, Engler AJ, Urnov F, Topol EJ, Torkamani A, Baldwin KK. Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing. Cell. PMID 30528432 DOI: 10.1016/J.Cell.2018.11.014 |
0.565 |
|
| 2018 |
Beri P, Matte BF, Fattet L, Kim D, Yang J, Engler AJ. Biomaterials to model and measure epithelial cancers. Nature Reviews. Materials. 3: 418-430. PMID 30416759 DOI: 10.1038/S41578-018-0051-6 |
0.8 |
|
| 2018 |
Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, ... ... Engler AJ, et al. RAP2 mediates mechanoresponses of the Hippo pathway. Nature. PMID 30135582 DOI: 10.1038/S41586-018-0444-0 |
0.801 |
|
| 2018 |
Sessions AO, Min P, Cordes T, Weickert BJ, Divakaruni AS, Murphy AN, Metallo CM, Engler AJ. Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span. Apl Bioengineering. 2. PMID 30105314 DOI: 10.1063/1.5019592 |
0.778 |
|
| 2018 |
Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, et al. Extracellular matrix in lung development, homeostasis and disease. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29524630 DOI: 10.1016/J.Matbio.2018.03.005 |
0.314 |
|
| 2018 |
Gibbons MC, Fisch KM, Pichika R, Cheng T, Engler AJ, Schenk S, Lane JG, Singh A, Ward SR. Heterogeneous muscle gene expression patterns in patients with massive rotator cuff tears. Plos One. 13: e0190439. PMID 29293645 DOI: 10.1371/Journal.Pone.0190439 |
0.634 |
|
| 2017 |
Placone JK, Engler AJ. Recent Advances in Extrusion-Based 3D Printing for Biomedical Applications. Advanced Healthcare Materials. PMID 29283220 DOI: 10.1002/Adhm.201701161 |
0.703 |
|
| 2017 |
Kumar A, Placone JK, Engler AJ. Understanding the extracellular forces that determine cell fate and maintenance. Development (Cambridge, England). 144: 4261-4270. PMID 29183939 DOI: 10.1242/Dev.158469 |
0.813 |
|
| 2017 |
Gibbons MC, Singh A, Engler AJ, Ward SR. The Role of Mechanobiology in Progression of Rotator Cuff Muscle Atrophy and Degeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28755470 DOI: 10.1002/Jor.23662 |
0.648 |
|
| 2017 |
Barker TH, Engler AJ. The provisional matrix: setting the stage for tissue repair outcomes. Matrix Biology : Journal of the International Society For Matrix Biology. 60: 1-4. PMID 28527902 DOI: 10.1016/J.Matbio.2017.04.003 |
0.339 |
|
| 2017 |
Hadden WJ, Young JL, Holle AW, McFetridge ML, Kim DY, Wijesinghe P, Taylor-Weiner H, Wen JH, Lee AR, Bieback K, Vo BN, Sampson DD, Kennedy BF, Spatz JP, Engler AJ, et al. Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. Proceedings of the National Academy of Sciences of the United States of America. PMID 28507138 DOI: 10.1073/Pnas.1618239114 |
0.821 |
|
| 2017 |
Happe CL, Tenerelli KP, Gromova AK, Kolb F, Engler AJ. Mechanically Patterned Neuromuscular Junctions-in-a-dish Have Improved Functional Maturation. Molecular Biology of the Cell. PMID 28495800 DOI: 10.1091/Mbc.E17-01-0046 |
0.386 |
|
| 2017 |
Herum KM, Choppe J, Kumar A, Engler AJ, McCulloch AD. Mechanical regulation of cardiac fibroblast pro-fibrotic phenotypes. Molecular Biology of the Cell. PMID 28468977 DOI: 10.1091/Mbc.E17-01-0014 |
0.626 |
|
| 2017 |
Fuhrmann A, Banisadr A, Beri P, Tlsty TD, Engler AJ. Metastatic State of Cancer Cells May Be Indicated by Adhesion Strength. Biophysical Journal. 112: 736-745. PMID 28256233 DOI: 10.1016/J.Bpj.2016.12.038 |
0.812 |
|
| 2017 |
Gibbons MC, Singh A, Anakwenze O, Cheng T, Pomerantz M, Schenk S, Engler AJ, Ward SR. Histological Evidence of Muscle Degeneration in Advanced Human Rotator Cuff Disease. The Journal of Bone and Joint Surgery. American Volume. 99: 190-199. PMID 28145949 DOI: 10.2106/Jbjs.16.00335 |
0.629 |
|
| 2017 |
Blice-Baum AC, Zambon AC, Kaushik G, Viswanathan MC, Engler AJ, Bodmer R, Cammarato A. Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age-associated functional decline. Aging Cell. 16: 93-103. PMID 28090761 DOI: 10.1111/Acel.12543 |
0.637 |
|
| 2017 |
Sessions AO, Kaushik G, Parker S, Raedschelders K, Bodmer R, Van Eyk JE, Engler AJ. Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan. Matrix Biology : Journal of the International Society For Matrix Biology. 62: 15-27. PMID 27793636 DOI: 10.1016/J.Matbio.2016.10.008 |
0.794 |
|
| 2016 |
Holle AW, McIntyre AJ, Kehe J, Wijesekara P, Young JL, Vincent LG, Engler AJ. High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 8: 1049-1058. PMID 27723854 DOI: 10.1039/C6Ib00076B |
0.819 |
|
| 2016 |
Thomas KA, Gibbons MC, Lane JG, Singh A, Ward SR, Engler AJ. Rotator cuff tear state modulates self-renewal and differentiation capacity of human skeletal muscle progenitor cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27699827 DOI: 10.1002/Jor.23453 |
0.748 |
|
| 2016 |
Sessions AO, Engler AJ. Mechanical Regulation of Cardiac Aging in Model Systems. Circulation Research. 118: 1553-62. PMID 27174949 DOI: 10.1161/Circresaha.116.307472 |
0.789 |
|
| 2016 |
Gibbons MC, Sato EJ, Bachasson D, Cheng T, Azimi H, Schenk S, Engler AJ, Singh A, Ward SR. Muscle architectural changes after Massive human rotator cuff tear. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27061583 DOI: 10.1002/Jor.23256 |
0.633 |
|
| 2016 |
Zhang ZN, Freitas BC, Qian H, Lux J, Acab A, Trujillo CA, Herai RH, Nguyen Huu VA, Wen JH, Joshi-Barr S, Karpiak JV, Engler AJ, Fu XD, Muotri AR, Almutairi A. Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 26944080 DOI: 10.1073/Pnas.1521255113 |
0.701 |
|
| 2016 |
Happe CL, Engler AJ. Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. Circulation Research. 118: 296-310. PMID 26838315 DOI: 10.1161/Circresaha.115.305139 |
0.449 |
|
| 2016 |
Ondeck M, Engler A. Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel. Journal of Biomechanical Engineering. PMID 26746491 DOI: 10.1115/1.4032429 |
0.403 |
|
| 2016 |
Kaushik G, Van Eyk J, Cammarato A, Engler A. Vinculin Remodeling of the Sarcomere Lattice Regulates Contractile Function Biophysical Journal. 110: 94a. DOI: 10.1016/J.Bpj.2015.11.567 |
0.645 |
|
| 2015 |
Wen JH, Choi O, Taylor-Weiner H, Fuhrmann A, Karpiak JV, Almutairi A, Engler AJ. Haptotaxis is cell type specific and limited by substrate adhesiveness. Cellular and Molecular Bioengineering. 8: 530-542. PMID 26640598 DOI: 10.1007/S12195-015-0398-3 |
0.823 |
|
| 2015 |
Fuhrmann A, Engler AJ. The cytoskeleton regulates cell attachment strength. Biophysical Journal. 109: 57-65. PMID 26153702 DOI: 10.1016/J.Bpj.2015.06.003 |
0.43 |
|
| 2015 |
Wu H, Lee J, Vincent LG, Wang Q, Gu M, Lan F, Churko JM, Sallam KI, Matsa E, Sharma A, Gold JD, Engler AJ, Xiang YK, Bers DM, Wu JC. Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. Cell Stem Cell. 17: 89-100. PMID 26095046 DOI: 10.1016/J.Stem.2015.04.020 |
0.762 |
|
| 2015 |
Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, Fuhrmann A, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, ... ... Engler AJ, et al. Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. Science Translational Medicine. 7: 292ra99. PMID 26084806 DOI: 10.1126/Scitranslmed.Aaa5843 |
0.785 |
|
| 2015 |
Meyer GA, Gibbons MC, Sato E, Lane JG, Ward SR, Engler AJ. Epimuscular Fat in the Human Rotator Cuff Is a Novel Beige Depot. Stem Cells Translational Medicine. 4: 764-74. PMID 25999520 DOI: 10.5966/Sctm.2014-0287 |
0.746 |
|
| 2015 |
Taylor-Weiner H, Ravi N, Engler AJ. Traction forces mediated by integrin signaling are necessary for definitive endoderm specification. Journal of Cell Science. 128: 1961-8. PMID 25908864 DOI: 10.1242/Dev.126243 |
0.822 |
|
| 2015 |
Jun I, Lee YB, Choi YS, Engler AJ, Park H, Shin H. Transfer stamping of human mesenchymal stem cell patches using thermally expandable hydrogels with tunable cell-adhesive properties. Biomaterials. 54: 44-54. PMID 25907038 DOI: 10.1016/J.Biomaterials.2015.03.016 |
0.696 |
|
| 2015 |
Hribar KC, Finlay D, Ma X, Qu X, Ondeck MG, Chung PH, Zanella F, Engler AJ, Sheikh F, Vuori K, Chen SC. Nonlinear 3D projection printing of concave hydrogel microstructures for long-term multicellular spheroid and embryoid body culture. Lab On a Chip. 15: 2412-8. PMID 25900329 DOI: 10.1039/C5Lc00159E |
0.342 |
|
| 2015 |
Wei SC, Fattet L, Tsai JH, Guo Y, Pai VH, Majeski HE, Chen AC, Sah RL, Taylor SS, Engler AJ, Yang J. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nature Cell Biology. 17: 678-88. PMID 25893917 DOI: 10.1038/Ncb3157 |
0.386 |
|
| 2015 |
Viswanathan P, Ondeck MG, Chirasatitsin S, Ngamkham K, Reilly GC, Engler AJ, Battaglia G. 3D surface topology guides stem cell adhesion and differentiation. Biomaterials. 52: 140-7. PMID 25818420 DOI: 10.1016/J.Biomaterials.2015.01.034 |
0.819 |
|
| 2015 |
Fuhrmann A, Engler AJ. Acute shear stress direction dictates adherent cell remodeling and verifies shear profile of spinning disk assays. Physical Biology. 12: 016011. PMID 25619322 DOI: 10.1088/1478-3975/12/1/016011 |
0.405 |
|
| 2015 |
Meyer GA, Farris AL, Sato E, Gibbons M, Lane JG, Ward SR, Engler AJ. Muscle progenitor cell regenerative capacity in the torn rotator cuff. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 421-9. PMID 25410765 DOI: 10.1002/Jor.22786 |
0.734 |
|
| 2015 |
Thomas K, Engler AJ, Meyer GA. Extracellular matrix regulation in the muscle satellite cell niche. Connective Tissue Research. 56: 1-8. PMID 25047058 DOI: 10.3109/03008207.2014.947369 |
0.759 |
|
| 2015 |
Fuhrmann A, Engler AJ. The Cytoskeleton Regulates Cell Attachment Strength Biophysical Journal. 109: 57-65. DOI: 10.1016/j.bpj.2015.06.003 |
0.308 |
|
| 2015 |
Blice-Baum AC, Kaushik G, Viswanathan MC, Zambon AC, Engler AJ, Bodmer R, Cammarato A. Overexpression of Foxo in the Heart Ameliorates Performance Decline through Enhanced UPS Processing in Aging Drosophila Biophysical Journal. 108: 361a. DOI: 10.1016/J.Bpj.2014.11.1979 |
0.648 |
|
| 2015 |
Wen JH, Choi O, Taylor-Weiner H, Fuhrmann A, Karpiak JV, Almutairi A, Engler AJ. Haptotaxis is Cell Type Specific and Limited by Substrate Adhesiveness Cellular and Molecular Bioengineering. DOI: 10.1007/s12195-015-0398-3 |
0.688 |
|
| 2014 |
Hribar KC, Choi YS, Ondeck M, Engler AJ, Chen S. Digital Plasmonic Patterning for Localized Tuning of Hydrogel Stiffness. Advanced Functional Materials. 24: 4922-4926. PMID 26120293 DOI: 10.1002/Adfm.201400274 |
0.693 |
|
| 2014 |
Young JL, Kretchmer K, Ondeck MG, Zambon AC, Engler AJ. Mechanosensitive kinases regulate stiffness-induced cardiomyocyte maturation. Scientific Reports. 4: 6425. PMID 25236849 DOI: 10.1038/Srep06425 |
0.622 |
|
| 2014 |
Wen JH, Vincent LG, Fuhrmann A, Choi YS, Hribar KC, Taylor-Weiner H, Chen S, Engler AJ. Interplay of matrix stiffness and protein tethering in stem cell differentiation. Nature Materials. 13: 979-87. PMID 25108614 DOI: 10.1038/Nmat4051 |
0.819 |
|
| 2014 |
Kaushik G, Engler AJ. From stem cells to cardiomyocytes: The role of forces in cardiac maturation, aging, and disease Progress in Molecular Biology and Translational Science. 126: 219-242. PMID 25081620 DOI: 10.1016/B978-0-12-394624-9.00009-9 |
0.715 |
|
| 2014 |
Fuhrmann A, Li J, Chien S, Engler AJ. Cation type specific cell remodeling regulates attachment strength Plos One. 9. PMID 25014042 DOI: 10.1371/Journal.Pone.0102424 |
0.464 |
|
| 2014 |
Murphy WL, McDevitt TC, Engler AJ. Materials as stem cell regulators Nature Materials. 13: 547-557. PMID 24845994 DOI: 10.1038/Nmat3937 |
0.442 |
|
| 2014 |
Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell. 13: 431-40. PMID 24400780 DOI: 10.1111/Acel.12193 |
0.632 |
|
| 2014 |
Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A. A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. Circulation Research. 114: e6-17. PMID 24221941 DOI: 10.1161/Circresaha.114.302028 |
0.628 |
|
| 2014 |
Kaushik G, Spenlehauer A, Sessions A, Pohl D, Trujillo A, Bernstein SI, Bodmer R, Cammarato A, Engler AJ. Vinculin-Mediated Cytoskeletal Remodeling Modulates Cardiac Morphology and Contractile Function During Ageing Biophysical Journal. 106: 778a. DOI: 10.1016/J.Bpj.2013.11.4264 |
0.79 |
|
| 2014 |
Blice-Baum A, Kaushik G, Viswanathan MC, Bodmer R, Engler AJ, Cammarato A. Cardiac-Specific Overexpression of FOXO Affords Protection Against Age-Associated Decline in Cardiac Performance in the Drosophila Model Biophysical Journal. 106: 777a. DOI: 10.1016/J.Bpj.2013.11.4260 |
0.334 |
|
| 2014 |
Fuhrmann A, Engler AJ. Integrin Avidity and Cytoskeletal Remodeling Regulate Force-Mediated Cell Detachment Biophysical Journal. 106: 358a. DOI: 10.1016/J.Bpj.2013.11.2033 |
0.425 |
|
| 2013 |
Rao N, Grover GN, Vincent LG, Evans SC, Choi YS, Spencer KH, Hui EE, Engler AJ, Christman KL. A co-culture device with a tunable stiffness to understand combinatorial cell-cell and cell-matrix interactions. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1344-54. PMID 24061208 DOI: 10.1039/C3Ib40078F |
0.824 |
|
| 2013 |
Young DA, Choi YS, Engler AJ, Christman KL. Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue. Biomaterials. 34: 8581-8. PMID 23953825 DOI: 10.1016/J.Biomaterials.2013.07.103 |
0.71 |
|
| 2013 |
Holle AW, Tang X, Vijayraghavan D, Vincent LG, Fuhrmann A, Choi YS, Del Alamo JC, Engler AJ. In situ mechanotransduction via vinculin regulates stem cell differentiation Stem Cells. 31: 2467-2477. PMID 23897765 DOI: 10.1002/Stem.1490 |
0.833 |
|
| 2013 |
Taylor-Weiner H, Schwarzbauer JE, Engler AJ. Defined extracellular matrix components are necessary for definitive endoderm induction. Stem Cells (Dayton, Ohio). 31: 2084-94. PMID 23766144 DOI: 10.1002/Stem.1453 |
0.82 |
|
| 2013 |
Vincent LG, Engler AJ. Stem cell differentiation: Post-degradation forces kick in Nature Materials. 12: 384-386. PMID 23603879 DOI: 10.1038/Nmat3636 |
0.833 |
|
| 2013 |
Young JL, Tuler J, Braden R, Schüp-Magoffin P, Schaefer J, Kretchmer K, Christman KL, Engler AJ. In vivo response to dynamic hyaluronic acid hydrogels. Acta Biomaterialia. 9: 7151-7. PMID 23523533 DOI: 10.1016/J.Actbio.2013.03.019 |
0.603 |
|
| 2013 |
Joshi-Barr S, Karpiak JV, Ner Y, Wen JH, Engler AJ, Almutairi A. Density gradient multilayered polymerization (DGMP): a novel technique for creating multi-compartment, customizable scaffolds for tissue engineering. Journal of Visualized Experiments : Jove. PMID 23426045 DOI: 10.3791/50018 |
0.675 |
|
| 2013 |
Vincent LG, Choi YS, Alonso-Latorre B, Del Álamo JC, Engler AJ. Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength Biotechnology Journal. 8: 472-484. PMID 23390141 DOI: 10.1002/Biot.201200205 |
0.835 |
|
| 2013 |
Kiang JD, Wen JH, Del Álamo JC, Engler AJ. Dynamic and reversible surface topography influences cell morphology Journal of Biomedical Materials Research - Part A. 101: 2313-2321. PMID 23355509 DOI: 10.1002/Jbm.A.34543 |
0.704 |
|
| 2013 |
Chirasatitsin S, Viswanathan P, Battaglia G, Engler AJ. Directing stem cell fate in 3D through cell inert and adhesive diblock copolymer domains Asme 2013 Summer Bioengineering Conference, Sbc 2013. 1. DOI: 10.1115/SBC2013-14442 |
0.302 |
|
| 2012 |
Viswanathan P, Chirasatitsin S, Ngamkham K, Engler AJ, Battaglia G. Cell instructive microporous scaffolds through interface engineering. Journal of the American Chemical Society. 134: 20103-9. PMID 23163574 DOI: 10.1021/Ja308523F |
0.797 |
|
| 2012 |
Kshitiz, Park J, Kim P, Helen W, Engler AJ, Levchenko A, Kim DH. Control of stem cell fate and function by engineering physical microenvironments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1008-18. PMID 23077731 DOI: 10.1039/C2Ib20080E |
0.48 |
|
| 2012 |
Choi YS, Vincent LG, Lee AR, Kretchmer KC, Chirasatitsin S, Dobke MK, Engler AJ. The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices. Biomaterials. 33: 6943-51. PMID 22800539 DOI: 10.1016/J.Biomaterials.2012.06.057 |
0.82 |
|
| 2012 |
Kaushik G, Zambon AC, Fuhrmann A, Bernstein SI, Bodmer R, Engler AJ, Cammarato A. Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. Journal of Cellular and Molecular Medicine. 16: 1656-62. PMID 22225769 DOI: 10.1111/J.1582-4934.2011.01517.X |
0.643 |
|
| 2012 |
Choi YS, Vincent LG, Lee AR, Dobke MK, Engler AJ. Mechanical derivation of functional myotubes from adipose-derived stem cells. Biomaterials. 33: 2482-91. PMID 22197570 DOI: 10.1016/J.Biomaterials.2011.12.004 |
0.835 |
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| 2012 |
Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Engler A, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127 |
0.781 |
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| 2012 |
Holle AW, Tang X, Tandon D, Fuhrmann A, Del Alamo JC, Engler AJ. Mechanosensitive Vinculin Signaling Regulates Stem Cell Fate Biophysical Journal. 102: 177a. DOI: 10.1016/J.Bpj.2011.11.959 |
0.801 |
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| 2012 |
Young JL, Schaefer J, Tuler J, Schup-Magoffin P, Braden R, Christman KL, Engler AJ. In Vivo Application of Dynamic Hyaluronic Acid Material for Myocardial Infarction Therapy Biophysical Journal. 102: 720a. DOI: 10.1016/J.Bpj.2011.11.3907 |
0.659 |
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| 2012 |
Taylor-Weiner H, Engler AJ. Extracellular Matrix Proteins are Necessary for Mouse Embryonic Stem Cell Differentiation and May Guide Stem Cell Fate Biophysical Journal. 102: 719a. DOI: 10.1016/J.Bpj.2011.11.3900 |
0.831 |
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| 2012 |
Vincent LG, Yong T, del Alamo JC, Poh Tan L, Engler AJ. Cell Aspect Ratio Alters Stem Cell Traction Stresses and Lineage Biophysical Journal. 102: 716a. DOI: 10.1016/J.Bpj.2011.11.3886 |
0.821 |
|
| 2012 |
Fuhrmann A, Engler AJ. Cell Detachment Mechanisms under Closer Investigation - the Role of Fate, Elasticity and Intra-Lineage Adhesion Heterogeneity Biophysical Journal. 102: 707a. DOI: 10.1016/J.Bpj.2011.11.3836 |
0.513 |
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| 2012 |
Wen JH, Tse JR, Engler AJ. Mesenchymal Stem Cells Duro- and Hapto- Taxis Alters Cell State Biophysical Journal. 102: 706a. DOI: 10.1016/J.Bpj.2011.11.3831 |
0.758 |
|
| 2012 |
Kiang J, Sniadecki N, Engler AJ. Dynamic Surface Topography Influences Cell Function Biophysical Journal. 102: 705a. DOI: 10.1016/J.Bpj.2011.11.3829 |
0.424 |
|
| 2012 |
Vincent LG, Suk Choi Y, Engler AJ. Human Mesenchymal Stem Cells Migration on Matrices with Distinct Elasticity Gradient Magnitudes Biophysical Journal. 102: 705a. DOI: 10.1016/J.Bpj.2011.11.3828 |
0.819 |
|
| 2012 |
Kaushik G, Fuhrmann A, Cammarato A, Engler AJ. In Situ Mechanical Analysis of Genetic Modification and Aging on Soft, Bilayered Drosophila Myocardium Biophysical Journal. 102: 351a. DOI: 10.1016/J.Bpj.2011.11.1922 |
0.655 |
|
| 2012 |
Kaushik G, Nishimura M, Graham S, Fuhrmann A, Bodmer R, Cammarato A, Engler AJ. Genetic Variation Results in Differing Age-Related Drosophila Myocardial Stiffness Biophysical Journal. 102: 350a-351a. DOI: 10.1016/J.Bpj.2011.11.1921 |
0.641 |
|
| 2011 |
Kaushik G, Fuhrmann A, Cammarato A, Engler AJ. In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium. Biophysical Journal. 101: 2629-37. PMID 22261050 DOI: 10.1016/J.Bpj.2011.10.042 |
0.65 |
|
| 2011 |
Holle AW, Engler AJ. More than a feeling: discovering, understanding, and influencing mechanosensing pathways. Current Opinion in Biotechnology. 22: 648-54. PMID 21536426 DOI: 10.1016/J.Copbio.2011.04.007 |
0.728 |
|
| 2011 |
LoPresti C, Massignani M, Fernyhough C, Blanazs A, Ryan AJ, Madsen J, Warren NJ, Armes SP, Lewis AL, Chirasatitsin S, Engler AJ, Battaglia G. Controlling polymersome surface topology at the nanoscale by membrane confined polymer/polymer phase separation. Acs Nano. 5: 1775-84. PMID 21344879 DOI: 10.1021/Nn102455Z |
0.773 |
|
| 2011 |
Tse JR, Engler AJ. Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate. Plos One. 6: e15978. PMID 21246050 DOI: 10.1371/Journal.Pone.0015978 |
0.489 |
|
| 2011 |
Young JL, Engler AJ. Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro. Biomaterials. 32: 1002-9. PMID 21071078 DOI: 10.1016/J.Biomaterials.2010.10.020 |
0.663 |
|
| 2011 |
Vincent L, Engler AJ. Effect of substrate modulus on cell function and differentiation Comprehensive Biomaterials. 5: 51-63. |
0.799 |
|
| 2011 |
Viswanathan P, Chirasatitsin S, Reilly G, Engler A, Battaglia G. 3D cell instructive scaffolds to direct stem cell fate Technical Proceedings of the 2011 Nsti Nanotechnology Conference and Expo, Nsti-Nanotech 2011. 3: 256-259. |
0.322 |
|
| 2010 |
Chirasatitsin S, Engler AJ. Detecting cell-adhesive sites in extracellular matrix using force spectroscopy mapping. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 22: 194102. PMID 21152375 DOI: 10.1088/0953-8984/22/19/194102 |
0.807 |
|
| 2010 |
Flores-Merino MV, Chirasatitsin S, Lopresti C, Reilly GC, Battaglia G, Engler AJ. Nanoscopic mechanical anisotropy in hydrogel surfaces. Soft Matter. 6: 4466-4470. PMID 20953281 DOI: 10.1039/C0Sm00339E |
0.802 |
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| 2010 |
Tse JR, Engler AJ. Preparation of hydrogel substrates with tunable mechanical properties. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 10.16. PMID 20521229 DOI: 10.1002/0471143030.Cb1016S47 |
0.459 |
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| 2010 |
Holle AW, Engler AJ. Cell rheology: Stressed-out stem cells. Nature Materials. 9: 4-6. PMID 20019660 DOI: 10.1038/Nmat2589 |
0.784 |
|
| 2010 |
David Merryman W, Engler AJ. Innovations in cell mechanobiology. Journal of Biomechanics. 43: 1. PMID 19815212 DOI: 10.1016/J.Jbiomech.2009.09.001 |
0.4 |
|
| 2010 |
Reilly GC, Engler AJ. Intrinsic extracellular matrix properties regulate stem cell differentiation. Journal of Biomechanics. 43: 55-62. PMID 19800626 DOI: 10.1016/J.Jbiomech.2009.09.009 |
0.517 |
|
| 2010 |
Rehfeldt F, Engler AJ, Discher DE. Stem Cells and Nanomedicine: Nanomechanics of the Microenvironment Nanotechnology. 305-322. DOI: 10.1002/9783527628155.Nanotech058 |
0.624 |
|
| 2009 |
Sen S, Engler AJ, Discher DE. Matrix strains induced by cells: Computing how far cells can feel. Cellular and Molecular Bioengineering. 2: 39-48. PMID 20582230 DOI: 10.1007/S12195-009-0052-Z |
0.718 |
|
| 2009 |
Engler AJ, Chan M, Boettiger D, Schwarzbauer JE. A novel mode of cell detachment from fibrillar fibronectin matrix under shear. Journal of Cell Science. 122: 1647-53. PMID 19401337 DOI: 10.1242/Jcs.040824 |
0.646 |
|
| 2009 |
Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM. Multiscale modeling of form and function. Science (New York, N.Y.). 324: 208-12. PMID 19359578 DOI: 10.1126/Science.1170107 |
0.41 |
|
| 2009 |
Oh S, Brammer KS, Li YS, Teng D, Engler AJ, Chien S, Jin S. Stem cell fate dictated solely by altered nanotube dimension. Proceedings of the National Academy of Sciences of the United States of America. 106: 2130-5. PMID 19179282 DOI: 10.1073/Pnas.0813200106 |
0.461 |
|
| 2009 |
Oh S, Brammer KS, Li YSJ, Teng D, Engler AJ, Chien S, Jin S. Reply to von der Mark et al.: Looking further into the effects of nanotube dimension on stem cell fate Proceedings of the National Academy of Sciences of the United States of America. 106: E61. DOI: 10.1073/Pnas.0904869106 |
0.349 |
|
| 2009 |
Carag C, Engler A, Discher DE. Elastic Matrices that mimic normal heart are best for beating Cardiomyocytes - Beating stops on mechanical mimics of Scars Biophysical Journal. 96: 523a. DOI: 10.1016/J.Bpj.2008.12.2699 |
0.626 |
|
| 2009 |
Engler AJ, Schwarzbauer J. Biophysical Regulation of Endoderm By 3-Dimensional Fibronectin Matrix Biophysical Journal. 96: 317a. DOI: 10.1016/J.Bpj.2008.12.1586 |
0.656 |
|
| 2009 |
Helen W, Schwarzbauer JE, Engler AJ. Stem cells are "Touch-Feely": A role for extracellular matrix in differentiation and disease European Cells and Materials. 18: 22. |
0.587 |
|
| 2008 |
Engler AJ, Carag-Krieger C, Johnson CP, Raab M, Tang HY, Speicher DW, Sanger JW, Sanger JM, Discher DE. Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating. Journal of Cell Science. 121: 3794-802. PMID 18957515 DOI: 10.1242/Jcs.029678 |
0.841 |
|
| 2008 |
Williams CM, Engler AJ, Slone RD, Galante LL, Schwarzbauer JE. Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation. Cancer Research. 68: 3185-92. PMID 18451144 DOI: 10.1158/0008-5472.Can-07-2673 |
0.635 |
|
| 2007 |
Engler AJ, Sweeney HL, Discher DE, Schwarzbauer JE. Extracellular matrix elasticity directs stem cell differentiation. Journal of Musculoskeletal & Neuronal Interactions. 7: 335. PMID 18094500 |
0.692 |
|
| 2007 |
Rehfeldt F, Engler AJ, Eckhardt A, Ahmed F, Discher DE. Cell responses to the mechanochemical microenvironment--implications for regenerative medicine and drug delivery. Advanced Drug Delivery Reviews. 59: 1329-39. PMID 17900747 DOI: 10.1016/J.Addr.2007.08.007 |
0.742 |
|
| 2007 |
Engler AJ, Rehfeldt F, Sen S, Discher DE. Microtissue elasticity: measurements by atomic force microscopy and its influence on cell differentiation. Methods in Cell Biology. 83: 521-45. PMID 17613323 DOI: 10.1016/S0091-679X(07)83022-6 |
0.707 |
|
| 2007 |
Frey MT, Engler A, Discher DE, Lee J, Wang YL. Microscopic methods for measuring the elasticity of gel substrates for cell culture: microspheres, microindenters, and atomic force microscopy. Methods in Cell Biology. 83: 47-65. PMID 17613304 DOI: 10.1016/S0091-679X(07)83003-2 |
0.576 |
|
| 2006 |
Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 126: 677-89. PMID 16923388 DOI: 10.1016/J.Cell.2006.06.044 |
0.729 |
|
| 2006 |
Brown AG, Leite RS, Engler AJ, Discher DE, Strauss JF. A hemoglobin fragment found in cervicovaginal fluid from women in labor potentiates the action of agents that promote contraction of smooth muscle cells. Peptides. 27: 1794-800. PMID 16621150 DOI: 10.1016/J.Peptides.2006.03.015 |
0.476 |
|
| 2006 |
Berry MF, Engler AJ, Woo YJ, Pirolli TJ, Bish LT, Jayasankar V, Morine KJ, Gardner TJ, Discher DE, Sweeney HL. Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2196-203. PMID 16473959 DOI: 10.1152/Ajpheart.01017.2005 |
0.536 |
|
| 2006 |
Sen S, Engler A, Discher D. Cells feel matrix stiffness—Simple models and computational insights Journal of Biomechanics. 39: S398. DOI: 10.1016/S0021-9290(06)84610-5 |
0.648 |
|
| 2006 |
Engler A, Sen S, Discher D. Matrix elasticity directs stem cell differentiation Journal of Biomechanics. 39: S269. DOI: 10.1016/S0021-9290(06)84031-5 |
0.703 |
|
| 2005 |
Dahl KN, Engler AJ, Pajerowski JD, Discher DE. Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures. Biophysical Journal. 89: 2855-64. PMID 16055543 DOI: 10.1529/Biophysj.105.062554 |
0.78 |
|
| 2005 |
Engler AJ, Eckhardt A, Richert L, Picart C, Discher DE. Determining molecular length scales: Correlating cell spreading on nano-thin gels and films and tissue elasticity Proceedings of the 2005 Summer Bioengineering Conference. 2005: 471-472. |
0.444 |
|
| 2005 |
Engler AJ, Berry MF, Sweeney HL, Discher DE. Substrate stiffness directs mesenchymal stem cell differentiation Proceedings of the 2005 Summer Bioengineering Conference. 2005: 311-312. |
0.546 |
|
| 2005 |
Engler A, Discher DE. Substrate softness directs differentiation of human stem cells Aiche Annual Meeting, Conference Proceedings. 8828. |
0.529 |
|
| 2004 |
Engler AJ, Griffin MA, Sen S, Bönnemann CG, Sweeney HL, Discher DE. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. The Journal of Cell Biology. 166: 877-87. PMID 15364962 DOI: 10.1083/Jcb.200405004 |
0.79 |
|
| 2004 |
Richert L, Engler AJ, Discher DE, Picart C. Elasticity of native and cross-linked polyelectrolyte multilayer films. Biomacromolecules. 5: 1908-16. PMID 15360305 DOI: 10.1021/Bm0498023 |
0.46 |
|
| 2004 |
Dalhaimer P, Engler AJ, Parthasarathy R, Discher DE. Targeted worm micelles. Biomacromolecules. 5: 1714-9. PMID 15360279 DOI: 10.1021/Bm049884V |
0.731 |
|
| 2004 |
Griffin MA, Engler AJ, Barber TA, Healy KE, Sweeney HL, Discher DE. Patterning, prestress, and peeling dynamics of myocytes. Biophysical Journal. 86: 1209-22. PMID 14747355 DOI: 10.1016/S0006-3495(04)74195-8 |
0.723 |
|
| 2004 |
Engler A, Bacakova L, Newman C, Hategan A, Griffin M, Discher D. Substrate Compliance versus Ligand Density in Cell on Gel Responses Biophysical Journal. 86: 617-628. PMID 14695306 DOI: 10.1016/S0006-3495(04)74140-5 |
0.741 |
|
| 2004 |
Engler AJ, Richert L, Wong JY, Picart C, Discher DE. Surface probe measurements of the elasticity of sectioned tissue, thin gels and polyelectrolyte multilayer films: Correlations between substrate stiffness and cell adhesion Surface Science. 570: 142-154. DOI: 10.1016/J.Susc.2004.06.179 |
0.575 |
|
| 2004 |
Zaari N, Rajagopalan P, Kim SK, Engler AJ, Wong JY. Photopolymerization in microfluidic gradient generators: Microscale control of substrate compliance to manipulate cell response Advanced Materials. 16: 2133-2137. DOI: 10.1002/Adma.200400883 |
0.359 |
|
| 2002 |
Engler A, Newman C, Hategan A, Sheehan M, Discher D. Cells on gels: Smooth and skeletal muscle cell responses to substrate compliance Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 402-403. |
0.51 |
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