David A. Christian, Ph.D. - Publications

University of Pennsylvania, Philadelphia, PA, United States 
cell biophysics and polymer engineering

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Clark JT, Christian DA, Gullicksrud JA, Perry JA, Park J, Jacquet M, Tarrant JC, Radaelli E, Silver J, Hunter CA. IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to . Elife. 10. PMID 33929319 DOI: 10.7554/eLife.65614  1
2021 Singh N, Frey NV, Engels B, Barrett DM, Shestova O, Ravikumar P, Cummins KD, Lee YG, Pajarillo R, Chun I, Shyu A, Highfill SL, Price A, Zhao L, Peng L, ... ... Christian DA, et al. Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells. Nature Medicine. PMID 33888899 DOI: 10.1038/s41591-021-01326-5  1
2020 Chen L, Christian DA, Kochanowsky JA, Phan AT, Clark JT, Wang S, Berry C, Oh J, Chen X, Roos DS, Beiting DP, Koshy AA, Hunter CA. The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses. The Journal of Experimental Medicine. 217. PMID 31961916 DOI: 10.1084/Jem.20181757  1
2019 DeLaney AA, Berry CT, Christian DA, Hart A, Bjanes E, Wynosky-Dolfi MA, Li X, Tummers B, Udalova IA, Chen YH, Hershberg U, Freedman BD, Hunter CA, Brodsky IE. Caspase-8 promotes c-Rel-dependent inflammatory cytokine expression and resistance against . Proceedings of the National Academy of Sciences of the United States of America. PMID 31147458 DOI: 10.1073/Pnas.1820529116  1
2019 Wang S, El-Fahmawi A, Christian DA, Fang Q, Radaelli E, Chen L, Sullivan MC, Misic AM, Ellringer JA, Zhu XQ, Winter SE, Hunter CA, Beiting DP. Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production. Mbio. 10. PMID 31138751 DOI: 10.1128/Mbio.00935-19  1
2017 Mahmud A, Harada T, Rajagopal K, Christian DA, Nair P, Murphy R, Discher DE. Spray stability of self-assembled filaments for delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28549950 DOI: 10.1016/J.Jconrel.2017.05.026  1
2017 O'Brien CA, Overall C, Konradt C, O'Hara Hall AC, Hayes NW, Wagage S, John B, Christian DA, Hunter CA, Harris TH. CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28389591 DOI: 10.4049/Jimmunol.1601581  1
2017 Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Christian DA, Harms Pritchard G, Fang Q, Buza EL, Jain D, Elloso MM, López CB, Hunter CA. IL-27 LIMITS TYPE 2 IMMUNOPATHOLOGY FOLLOWING PARAINFLUENZA VIRUS INFECTION. Plos Pathogens. 13: e1006173. PMID 28129374 DOI: 10.1371/Journal.Ppat.1006173  1
2017 Ruella M, Maude SL, Engels B, Barrett DM, Frey N, Marcucci KT, Shestova O, Singh N, Perazzelli J, Christian DA, Haagen D, Lacey SF, Melenhorst JJ, Brogdon J, Young RM, et al. Clinical Efficacy of Anti-CD22 Chimeric Antigen Receptor T Cells for B-Cell Acute Lymphoblastic Leukemia Is Correlated with the Length of the Scfv Linker and Can be Predicted Using Xenograft Models Blood. 130: 807-807. DOI: 10.1182/Blood.V130.Suppl_1.807.807  1
2016 Konradt C, Ueno N, Christian DA, Delong JH, Pritchard GH, Herz J, Bzik DJ, Koshy AA, McGavern DB, Lodoen MB, Hunter CA. Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system. Nature Microbiology. 1: 16001. PMID 27572166 DOI: 10.1038/Nmicrobiol.2016.1  1
2016 Ruella M, Barrett DM, Kenderian SS, Shestova O, Hofmann TJ, Perazzelli J, Klichinsky M, Aikawa V, Nazimuddin F, Kozlowski M, Scholler J, Lacey SF, Melenhorst JJ, Morrissette JJ, Christian DA, et al. Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies. The Journal of Clinical Investigation. PMID 27571406 DOI: 10.1172/Jci87366  1
2016 Konradt C, Ueno N, Christian DA, Delong JH, Pritchard GH, Herz J, Bzik DJ, Koshy AA, McGavern DB, Lodoen MB, Hunter CA. Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system. Nature Microbiology. 1. PMID 27478622  1
2016 Weinkopff T, Konradt C, Christian DA, Discher DE, Hunter CA, Scott P. Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 27474074 DOI: 10.4049/Jimmunol.1600717  1
2015 Dupont CD, Harms Pritchard G, Hidano S, Christian DA, Wagage S, Muallem G, Tait Wojno ED, Hunter CA. Flt3 Ligand Is Essential for Survival and Protective Immune Responses during Toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 26385522 DOI: 10.4049/Jimmunol.1500690  1
2015 Banigan EJ, Harris TH, Christian DA, Hunter CA, Liu AJ. Heterogeneous CD8+ T cell migration in the lymph node in the absence of inflammation revealed by quantitative migration analysis. Plos Computational Biology. 11: e1004058. PMID 25692801 DOI: 10.1371/Journal.Pcbi.1004058  1
2015 Harms Pritchard G, Hall AO, Christian DA, Wagage S, Fang Q, Muallem G, John B, Glatman Zaretsky A, Dunn WG, Perrigoue J, Reiner SL, Hunter CA. Diverse roles for T-bet in the effector responses required for resistance to infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 1131-40. PMID 25556247 DOI: 10.4049/Jimmunol.1401617  1
2014 Hunter C, Christian D. Parasite uses host NFAT to co-opt immune response. The Journal of Experimental Medicine. 211: 1923. PMID 25246389 DOI: 10.1084/Jem.21110Insight2  1
2014 Christian DA, Koshy AA, Reuter MA, Betts MR, Boothroyd JC, Hunter CA. Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis. Infection and Immunity. 82: 4056-67. PMID 25024368 DOI: 10.1128/Iai.01643-14  1
2014 Dupont CD, Christian DA, Selleck EM, Pepper M, Leney-Greene M, Harms Pritchard G, Koshy AA, Wagage S, Reuter MA, Sibley LD, Betts MR, Hunter CA. Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii. Plos Pathogens. 10: e1004047. PMID 24722202 DOI: 10.1371/Journal.Ppat.1004047  1
2014 Beiting DP, Peixoto L, Akopyants NS, Beverley SM, Wherry EJ, Christian DA, Hunter CA, Brodsky IE, Roos DS. Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. Plos One. 9: e88398. PMID 24505488 DOI: 10.1371/Journal.Pone.0088398  1
2014 Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE. Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells. Cell Stem Cell. 14: 81-93. PMID 24268694 DOI: 10.1016/J.Stem.2013.10.009  1
2013 Rodriguez PL, Harada T, Christian DA, Pantano DA, Tsai RK, Discher DE. Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles. Science (New York, N.Y.). 339: 971-5. PMID 23430657 DOI: 10.1126/Science.1229568  1
2013 Spinler K, Tian A, Christian DA, Pantano DA, Baumgart T, Discher DE. Dynamic domains in polymersomes: mixtures of polyanionic and neutral diblocks respond more rapidly to changes in calcium than to pH. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 7499-508. PMID 23327600 DOI: 10.1021/La304602E  1
2012 Dupont CD, Christian DA, Hunter CA. Immune response and immunopathology during toxoplasmosis. Seminars in Immunopathology. 34: 793-813. PMID 22955326 DOI: 10.1007/S00281-012-0339-3  1
2012 Koshy AA, Dietrich HK, Christian DA, Melehani JH, Shastri AJ, Hunter CA, Boothroyd JC. Toxoplasma co-opts host cells it does not invade. Plos Pathogens. 8: e1002825. PMID 22910631 DOI: 10.1371/Journal.Ppat.1002825  1
2012 Harris TH, Banigan EJ, Christian DA, Konradt C, Tait Wojno ED, Norose K, Wilson EH, John B, Weninger W, Luster AD, Liu AJ, Hunter CA. Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. Nature. 486: 545-8. PMID 22722867 DOI: 10.1038/Nature11098  1
2012 Christian DA, Hunter CA. Particle-mediated delivery of cytokines for immunotherapy. Immunotherapy. 4: 425-41. PMID 22512636 DOI: 10.2217/Imt.12.26  1
2011 Ellenbroek WG, Wang YH, Christian DA, Discher DE, Janmey PA, Liu AJ. Divalent cation-dependent formation of electrostatic PIP2 clusters in lipid monolayers. Biophysical Journal. 101: 2178-84. PMID 22067156 DOI: 10.1016/J.Bpj.2011.09.039  1
2011 John B, Ricart B, Tait Wojno ED, Harris TH, Randall LM, Christian DA, Gregg B, De Almeida DM, Weninger W, Hammer DA, Hunter CA. Analysis of behavior and trafficking of dendritic cells within the brain during toxoplasmic encephalitis. Plos Pathogens. 7: e1002246. PMID 21949652 DOI: 10.1371/Journal.Ppat.1002246  1
2011 Whitmarsh RJ, Gray CM, Gregg B, Christian DA, May MJ, Murray PJ, Hunter CA. A critical role for SOCS3 in innate resistance to Toxoplasma gondii. Cell Host & Microbe. 10: 224-36. PMID 21925110 DOI: 10.1016/J.Chom.2011.07.009  1
2011 Loverde SM, Pantano DA, Christian DA, Mahmud A, Klein ML, Discher DE. Curvature, rigidity, and pattern formation in functional polymer micelles and vesicles-From dynamic visualization to molecular simulation Current Opinion in Solid State and Materials Science. 15: 277-284. DOI: 10.1016/J.Cossms.2011.06.003  1
2010 Christian DA, Garbuzenko OB, Minko T, Discher DE. Polymer Vesicles with a Red Cell-like Surface Charge: Microvascular Imaging and in vivo Tracking with Near-Infrared Fluorescence. Macromolecular Rapid Communications. 31: 135-41. PMID 21590885 DOI: 10.1002/Marc.200900589  1
2010 Rajagopal K, Mahmud A, Christian DA, Pajerowski JD, Brown AE, Loverde SM, Discher DE. Curvature-coupled hydration of Semicrystalline Polymer Amphiphiles yields flexible Worm Micelles but favors rigid Vesicles: polycaprolactone-based block copolymers. Macromolecules. 43: 9736-9746. PMID 21499509 DOI: 10.1021/Ma101316W  1
2010 Rajagopal K, Christian DA, Harada T, Tian A, Discher DE. Polymersomes and wormlike micelles made fluorescent by direct modifications of block copolymer amphiphiles International Journal of Polymer Science. 2010. DOI: 10.1155/2010/379286  1
2010 Cai S, Christian DA, Tewari M, Minko T, Discher DE. Anti-cancer polymersomes Rsc Nanoscience and Nanotechnology. 300-312.  1
2009 Christian DA, Tian A, Ellenbroek WG, Levental I, Rajagopal K, Janmey PA, Liu AJ, Baumgart T, Discher DE. Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding. Nature Materials. 8: 843-9. PMID 19734886 DOI: 10.1038/Nmat2512  1
2009 Levental I, Christian DA, Wang YH, Madara JJ, Discher DE, Janmey PA. Calcium-dependent lateral organization in phosphatidylinositol 4,5-bisphosphate (PIP2)- and cholesterol-containing monolayers. Biochemistry. 48: 8241-8. PMID 19630438 DOI: 10.1021/Bi9007879  1
2009 Christian DA, Cai S, Garbuzenko OB, Harada T, Zajac AL, Minko T, Discher DE. Flexible filaments for in vivo imaging and delivery: persistent circulation of filomicelles opens the dosage window for sustained tumor shrinkage. Molecular Pharmaceutics. 6: 1343-52. PMID 19249859 DOI: 10.1021/Mp900022M  1
2009 Christian DA, Cai S, Bowen DM, Kim Y, Pajerowski JD, Discher DE. Polymersome carriers: from self-assembly to siRNA and protein therapeutics. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 71: 463-74. PMID 18977437 DOI: 10.1016/J.Ejpb.2008.09.025  1
2009 Tong R, Christian DA, Tang L, Cabral H, Baker JR, Kataoka K, Discher DE, Cheng J. Nanopolymeric therapeutics Mrs Bulletin. 34: 422-431.  1
2008 Christian DA, Rajagopal K, Srinivas G, Klein ML, Discher DE. Nanoparticle incorporation and aggregation in block copolymer worm-like micelles Aiche Annual Meeting, Conference Proceedings 1
2008 Christian DA, Bowen DM, Dunn RJ, Discher DE. Anionic nano-polymersomes for enhanced circulation kinetics in vivo Aiche Annual Meeting, Conference Proceedings 1
2007 Discher DE, Ortiz V, Srinivas G, Klein ML, Kim Y, Christian D, Cai S, Photos P, Ahmed F. Emerging Applications of Polymersomes in Delivery: from Molecular Dynamics to Shrinkage of Tumors. Progress in Polymer Science. 32: 838-857. PMID 24692840 DOI: 10.1016/J.Progpolymsci.2007.05.011  1
2005 Kim Y, Dalhaimer P, Christian DA, Discher DE. Polymeric worm micelles as nano-carriers for drug delivery. Nanotechnology. 16: S484-91. PMID 21727469 DOI: 10.1088/0957-4484/16/7/024  1
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