David Klenerman - Publications

Affiliations: 
2011-2013 Chemistry University of Cambridge, Cambridge, England, United Kingdom 

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wiese M, Bannister AJ, Basu S, Boucher W, Wohlfahrt K, Christophorou MA, Nielsen ML, Klenerman D, Laue ED, Kouzarides T. Citrullination of HP1γ chromodomain affects association with chromatin. Epigenetics & Chromatin. 12: 21. PMID 30940194 DOI: 10.1186/s13072-019-0265-x  0.36
2019 Stern HL, Wang R, Fan Y, Mizuta R, Stewart JC, Needham LM, Roberts TD, Wai R, Ginsberg NS, Klenerman D, Hofmann S, Lee SF. Spectrally-Resolved Photodynamics Of Individual Emitters In Large-Area Monolayers Of Hexagonal-Boron Nitride. Acs Nano. PMID 30865421 DOI: 10.1021/acsnano.9b00274  0.56
2018 Ponjavic A, Ye Y, Laue E, Lee SF, Klenerman D. Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever. Biomedical Optics Express. 9: 5863-5880. PMID 31065399 DOI: 10.1364/BOE.9.005863  0.56
2018 Lee JE, Sang JC, Rodrigues M, Carr AR, Horrocks MH, De S, Bongiovanni MN, Flagmeier P, Dobson CM, Wales DJ, Lee SF, Klenerman D. Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale. Nano Letters. PMID 30380895 DOI: 10.1021/acs.nanolett.8b02916  0.56
2018 Taylor CG, Meisl G, Horrocks MH, Zetterberg H, Knowles TPJ, Klenerman D. Extrinsic Amyloid-Binding Dyes for the Detection of Individual Protein Aggregates in Solution. Analytical Chemistry. PMID 30059210 DOI: 10.1021/acs.analchem.8b02226  0.56
2018 Horrocks M, Whiten DR, Zuo Y, Calo L, Choi ML, De S, Flagmeier P, Wirthensohn DC, Kundel F, Lee SF, Dobson C, Gandhi S, Spillantini M, Klenerman D, Ranasinghe RT, et al. Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells. Chembiochem : a European Journal of Chemical Biology. PMID 30051958 DOI: 10.1002/cbic.201800209  0.56
2018 Whiten DR, Cox D, Horrocks MH, Taylor CG, De S, Flagmeier P, Tosatto L, Kumita JR, Ecroyd H, Dobson CM, Klenerman D, Wilson MR. Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers. Cell Reports. 23: 3492-3500. PMID 29924993 DOI: 10.1016/j.celrep.2018.05.074  0.56
2018 Ludtmann MHR, Angelova PR, Horrocks MH, Choi ML, Rodrigues M, Baev AY, Berezhnov AV, Yao Z, Little D, Banushi B, Al-Menhali AS, Ranasinghe RT, Whiten DR, Yapom R, Dolt KS, ... ... Klenerman D, et al. α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease. Nature Communications. 9: 2293. PMID 29895861 DOI: 10.1038/s41467-018-04422-2  0.56
2018 Ponjavic A, McColl J, Carr AR, Santos AM, Kulenkampff K, Lippert A, Davis SJ, Klenerman D, Lee SF. Single-Molecule Light-Sheet Imaging of Suspended T Cells. Biophysical Journal. 114: 2200-2211. PMID 29742413 DOI: 10.1016/j.bpj.2018.02.044  0.56
2018 Lee SF, Klenerman D. Weighing one protein with light. Science (New York, N.Y.). 360: 378-379. PMID 29700252 DOI: 10.1126/science.aat5851  0.56
2018 Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, ... Klenerman D, et al. Capturing resting T cells: the perils of PLL. Nature Immunology. PMID 29476188 DOI: 10.1038/s41590-018-0048-8  0.56
2018 Kundel F, Tosatto L, Whiten DR, Wirthensohn DC, Horrocks MH, Klenerman D. Shedding light on aberrant interactions: A review of modern tools for studying protein aggregates. The Febs Journal. PMID 29453901 DOI: 10.1111/febs.14409  0.56
2018 Ranasinghe RT, Challand MR, Ganzinger KA, Lewis BW, Softley C, Schmied WH, Horrocks MH, Shivji N, Chin JW, Spencer J, Klenerman D. Detecting RNA base methylations in single cells by in situ hybridization. Nature Communications. 9: 655. PMID 29440632 DOI: 10.1038/s41467-017-02714-7  0.56
2018 Cox D, Whiten DR, Brown J, Horrocks MH, San Gil R, Dobson CM, Klenerman D, van Oijen AM, Ecroyd H. The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity. The Journal of Biological Chemistry. PMID 29382725 DOI: 10.1074/jbc.M117.813865  0.56
2018 Varela JA, Rodrigues M, De S, Flagmeier P, Gandhi S, Dobson CM, Klenerman D, Lee S. Optical structural analysis of individual α-synuclein oligomers. Angewandte Chemie (International Ed. in English). PMID 29342318 DOI: 10.1002/anie.201710779  0.56
2018 Kundel F, De S, Flagmeier P, Horrocks MH, Kjaergaard M, Shammas SL, Jackson SE, Dobson CM, Klenerman D. Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity. Acs Chemical Biology. PMID 29300447 DOI: 10.1021/acschembio.7b01039  0.56
2017 Felce JH, Davis SJ, Klenerman D. Single-Molecule Analysis of G Protein-Coupled Receptor Stoichiometry: Approaches and Limitations. Trends in Pharmacological Sciences. PMID 29122289 DOI: 10.1016/j.tips.2017.10.005  0.44
2017 Felce JH, Latty SL, Knox RG, Mattick SR, Lui Y, Lee SF, Klenerman D, Davis SJ. Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure. Cell Reports. 20: 2654-2665. PMID 28903045 DOI: 10.1016/j.celrep.2017.08.072  0.56
2017 Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, ... ... Klenerman D, et al. Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species. Bmc Biology. 15: 57. PMID 28673288 DOI: 10.1186/s12915-017-0390-6  0.56
2017 Flagmeier P, De S, Wirthensohn DC, Lee SF, Vincke C, Muyldermans S, Knowles TPJ, Gandhi S, Dobson CM, Klenerman D. Ultrasensitive Measurement of Ca(2+) Influx into Lipid Vesicles Induced by Protein Aggregates. Angewandte Chemie (International Ed. in English). PMID 28474754 DOI: 10.1002/anie.201700966  0.56
2017 Carr AR, Ponjavic A, Basu S, McColl J, Santos AM, Davis S, Laue ED, Klenerman D, Lee SF. Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function. Biophysical Journal. 112: 1444-1454. PMID 28402886 DOI: 10.1016/j.bpj.2017.02.023  0.56
2016 Bongiovanni MN, Godet J, Horrocks MH, Tosatto L, Carr AR, Wirthensohn DC, Ranasinghe RT, Lee JE, Ponjavic A, Fritz JV, Dobson CM, Klenerman D, Lee SF. Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping. Nature Communications. 7: 13544. PMID 27929085 DOI: 10.1038/ncomms13544  0.56
2016 Iljina M, Tosatto L, Choi ML, Sang JC, Ye Y, Hughes CD, Bryant CE, Gandhi S, Klenerman D. Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein. Scientific Reports. 6: 33928. PMID 27671749 DOI: 10.1038/srep33928  0.96
2016 Clarke RW, Novak P, Zhukov A, Tyler EJ, Cano-Jaimez M, Drews A, Richards O, Volynski K, Bishop C, Klenerman D. Low Stress Ion Conductance Microscopy of Sub-Cellular Stiffness. Soft Matter. PMID 27604678 DOI: 10.1039/c6sm01106c  0.96
2016 Zhou Y, Basu S, Wohlfahrt KJ, Lee SF, Klenerman D, Laue ED, Seshia AA. A microfluidic platform for trapping, releasing and super-resolution imaging of single cells. Sensors and Actuators. B, Chemical. 232: 680-691. PMID 27594767 DOI: 10.1016/j.snb.2016.03.131  0.56
2016 Angelova PR, Ludtmann MH, Horrocks MH, Negoda A, Cremades N, Klenerman D, Dobson CM, Wood NW, Pavlov EV, Gandhi S, Abramov AY. Ca2+ is a key factor in α-synuclein-induced neurotoxicity. Development (Cambridge, England). 143: e1.1. PMID 27190039 DOI: 10.1242/dev.139345  0.56
2016 Zhang W, Aubert A, Gomez de Segura JM, Karuppasamy M, Basu S, Murthy A, Diamante A, Drury TA, Balmer J, Cramard J, Watson AA, Lando D, Lee SF, Palayret M, Kloet S, ... ... Klenerman D, et al. The Nucleosome Remodeling and Deacetylase Complex NuRD is built from preformed catalytically active sub-modules. Journal of Molecular Biology. PMID 27117189 DOI: 10.1016/j.jmb.2016.04.025  0.96
2016 Jönsson P, Southcombe JH, Santos AM, Huo J, Fernandes RA, McColl J, Lever M, Evans EJ, Hudson A, Chang VT, Hanke T, Godkin A, Dunne PD, Horrocks MH, Palayret M, ... ... Klenerman D, et al. Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114505 DOI: 10.1073/pnas.1513918113  0.96
2016 Broadhead MJ, Horrocks MH, Zhu F, Muresan L, Benavides-Piccione R, DeFelipe J, Fricker D, Kopanitsa MV, Duncan RR, Klenerman D, Komiyama NH, Lee SF, Grant SG. PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits. Scientific Reports. 6: 24626. PMID 27109929 DOI: 10.1038/srep24626  0.96
2016 Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jönsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJ, Klenerman D, et al. Initiation of T cell signaling by CD45 segregation at 'close contacts'. Nature Immunology. PMID 26998761 DOI: 10.1038/ni.3392  0.96
2016 Angelova PR, Ludtmann MH, Horrocks MH, Negoda A, Cremades N, Klenerman D, Dobson CM, Wood NW, Pavlov EV, Gandhi S, Abramov AY. Calcium is a key factor in α-synuclein induced neurotoxicity. Journal of Cell Science. PMID 26989132 DOI: 10.1242/jcs.180737  0.56
2016 Iljina M, Garcia GA, Horrocks MH, Tosatto L, Choi ML, Ganzinger KA, Abramov AY, Gandhi S, Wood NW, Cremades N, Dobson CM, Knowles TP, Klenerman D. Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884195 DOI: 10.1073/pnas.1524128113  0.96
2016 Zhang Y, Clausmeyer J, Babakinejad B, López Córdoba A, Ali T, Shevchuk A, Takahashi Y, Novak P, Edwards C, Lab M, Gopal S, Chiappini C, Anand U, Magnani L, Coombes C, ... ... Klenerman D, et al. Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis. Acs Nano. PMID 26816294 DOI: 10.1021/acsnano.5b05211  0.96
2016 Horrocks MH, Lee SF, Gandhi S, Magdalinou NK, Chen SW, Devine MJ, Tosatto L, Kjaergaard M, Beckwith JS, Zetterberg H, Iljina M, Cremades N, Dobson CM, Wood NW, Klenerman D. Single-molecule imaging of individual amyloid protein aggregates in human biofluids. Acs Chemical Neuroscience. PMID 26800462 DOI: 10.1021/acschemneuro.5b00324  0.96
2015 Tosatto L, Horrocks MH, Dear AJ, Knowles TP, Dalla Serra M, Cremades N, Dobson CM, Klenerman D. Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants. Scientific Reports. 5: 16696. PMID 26582456 DOI: 10.1038/srep16696  0.96
2015 Deas E, Cremades N, Angelova PR, Ludtmann M, Yao Z, Chen S, Horrocks M, Banushi B, Little D, Devine M, Gissen P, Klenerman D, Dobson C, Wood N, Gandhi S, et al. Alpha-synuclein oligomers interact with metal ions to induce oxidative stress and neuronal death in Parkinson's disease. Antioxidants & Redox Signaling. PMID 26564470 DOI: 10.1089/ars.2015.6343  0.96
2015 Latty SL, Felce JH, Weimann L, Lee SF, Davis SJ, Klenerman D. Referenced Single-Molecule Measurements Differentiate between GPCR Oligomerization States. Biophysical Journal. 109: 1798-806. PMID 26536257 DOI: 10.1016/j.bpj.2015.09.004  0.96
2015 Horrocks MH, Tosatto L, Dear AJ, Garcia GA, Iljina M, Cremades N, Dalla Serra M, Knowles TP, Dobson CM, Klenerman D. Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α-Synuclein Oligomers. Analytical Chemistry. 87: 8818-26. PMID 26258431 DOI: 10.1021/acs.analchem.5b01811  0.96
2015 Reeve AK, Ludtmann MH, Angelova PR, Simcox EM, Horrocks MH, Klenerman D, Gandhi S, Turnbull DM, Abramov AY. Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons. Cell Death & Disease. 6: e1820. PMID 26181201 DOI: 10.1038/cddis.2015.166  0.96
2015 Whitcomb DJ, Hogg EL, Regan P, Piers T, Narayan P, Whitehead G, Winters BL, Kim DH, Kim E, St George-Hyslop P, Klenerman D, Collingridge GL, Jo J, Cho K. Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus. Scientific Reports. 5: 10934. PMID 26055072 DOI: 10.1038/srep10934  0.96
2015 Shammas SL, Garcia GA, Kumar S, Kjaergaard M, Horrocks MH, Shivji N, Mandelkow E, Knowles TP, Mandelkow E, Klenerman D. A mechanistic model of tau amyloid aggregation based on direct observation of oligomers. Nature Communications. 6: 7025. PMID 25926130 DOI: 10.1038/ncomms8025  0.96
2015 Palayret M, Armes H, Basu S, Watson AT, Herbert A, Lando D, Etheridge TJ, Endesfelder U, Heilemann M, Laue E, Carr AM, Klenerman D, Lee SF. Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging. Plos One. 10: e0125438. PMID 25884495 DOI: 10.1371/journal.pone.0125438  0.96
2015 Chen SW, Drakulic S, Deas E, Ouberai M, Aprile FA, Arranz R, Ness S, Roodveldt C, Guilliams T, De-Genst EJ, Klenerman D, Wood NW, Knowles TP, Alfonso C, Rivas G, et al. Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation. Proceedings of the National Academy of Sciences of the United States of America. 112: E1994-2003. PMID 25855634 DOI: 10.1073/pnas.1421204112  0.96
2015 Ivanov AP, Actis P, Jönsson P, Klenerman D, Korchev Y, Edel JB. On-demand delivery of single DNA molecules using nanopipets. Acs Nano. 9: 3587-95. PMID 25794527 DOI: 10.1021/acsnano.5b00911  0.96
2015 Angelova PR, Horrocks MH, Klenerman D, Gandhi S, Abramov AY, Shchepinov MS. Lipid peroxidation is essential for α-synuclein-induced cell death. Journal of Neurochemistry. 133: 582-9. PMID 25580849 DOI: 10.1111/jnc.13024  0.96
2015 Tsytlonok M, Ibrahim SM, Rowling PJ, Xu W, Ruedas-Rama MJ, Orte A, Klenerman D, Itzhaki LS. Single-molecule FRET reveals hidden complexity in a protein energy landscape. Structure (London, England : 1993). 23: 190-8. PMID 25565106 DOI: 10.1016/j.str.2014.10.023  0.96
2015 Hell SW, Sahl SJ, Bates M, Zhuang X, Heintzmann R, Booth MJ, Bewersdorf J, Shtengel G, Hess H, Tinnefeld P, Honigmann A, Jakobs S, Testa I, Cognet L, Lounis B, ... ... Klenerman D, et al. The 2015 super-resolution microscopy roadmap Journal of Physics D: Applied Physics. 48. DOI: 10.1088/0022-3727/48/44/443001  0.96
2014 Bell L, Seshia A, Lando D, Laue E, Palayret M, Lee SF, Klenerman D. A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging. Sensors and Actuators. B, Chemical. 192: 36-41. PMID 25844024 DOI: 10.1016/j.snb.2013.10.002  0.56
2014 Ganzinger KA, Narayan P, Qamar SS, Weimann L, Ranasinghe RT, Aguzzi A, Dobson CM, McColl J, St George-Hyslop P, Klenerman D. Single-molecule imaging reveals that small amyloid-β1-42 oligomers interact with the cellular prion protein (PrP(C)). Chembiochem : a European Journal of Chemical Biology. 15: 2515-21. PMID 25294384 DOI: 10.1002/cbic.201402377  0.96
2014 Etheridge TJ, Boulineau RL, Herbert A, Watson AT, Daigaku Y, Tucker J, George S, Jönsson P, Palayret M, Lando D, Laue E, Osborne MA, Klenerman D, Lee SF, Carr AM. Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy Nucleic Acids Research. 42: e146. PMID 25106872 DOI: 10.1093/nar/gku726  0.96
2014 Murphy RR, Danezis G, Horrocks MH, Jackson SE, Klenerman D. Bayesian inference of accurate population sizes and FRET efficiencies from single diffusing biomolecules. Analytical Chemistry. 86: 8603-12. PMID 25105347 DOI: 10.1021/ac501188r  0.96
2014 Narayan P, Holmström KM, Kim DH, Whitcomb DJ, Wilson MR, St George-Hyslop P, Wood NW, Dobson CM, Cho K, Abramov AY, Klenerman D. Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage. Biochemistry. 53: 2442-53. PMID 24717093 DOI: 10.1021/bi401606f  0.96
2014 Novak P, Shevchuk A, Ruenraroengsak P, Miragoli M, Thorley AJ, Klenerman D, Lab MJ, Tetley TD, Gorelik J, Korchev YE. Imaging single nanoparticle interactions with human lung cells using fast ion conductance microscopy. Nano Letters. 14: 1202-7. PMID 24555574 DOI: 10.1021/nl404068p  0.96
2014 Del Linz S, Willman E, Caldwell M, Klenerman D, Fernández A, Moss G. Contact-free scanning and imaging with the scanning ion conductance microscope. Analytical Chemistry. 86: 2353-60. PMID 24521282 DOI: 10.1021/ac402748j  0.96
2014 Horrocks MH, Palayret M, Klenerman D, Lee SF. The changing point-spread function: single-molecule-based super-resolution imaging. Histochemistry and Cell Biology. 141: 577-85. PMID 24509806 DOI: 10.1007/s00418-014-1186-1  0.96
2014 Johansson B, Höök F, Klenerman D, Jönsson P. Label-free measurements of the diffusivity of molecules in lipid membranes. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 15: 486-91. PMID 24402971 DOI: 10.1002/cphc.201301136  0.96
2014 Actis P, Tokar S, Clausmeyer J, Babakinejad B, Mikhaleva S, Cornut R, Takahashi Y, López Córdoba A, Novak P, Shevchuck AI, Dougan JA, Kazarian SG, Gorelkin PV, Erofeev AS, Yaminsky IV, ... ... Klenerman D, et al. Electrochemical nanoprobes for single-cell analysis. Acs Nano. 8: 875-84. PMID 24377306 DOI: 10.1021/nn405612q  0.96
2014 Bell L, Seshia A, Lando D, Laue E, Palayret M, Lee SF, Klenerman D. A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging Sensors and Actuators, B: Chemical. 192: 36-41. DOI: 10.1016/j.snb.2013.10.002  0.96
2013 Novak P, Gorelik J, Vivekananda U, Shevchuk AI, Ermolyuk YS, Bailey RJ, Bushby AJ, Moss GW, Rusakov DA, Klenerman D, Kullmann DM, Volynski KE, Korchev YE. Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels. Neuron. 79: 1067-77. PMID 24050398 DOI: 10.1016/j.neuron.2013.07.012  0.96
2013 Babakinejad B, Jönsson P, López Córdoba A, Actis P, Novak P, Takahashi Y, Shevchuk A, Anand U, Anand P, Drews A, Ferrer-Montiel A, Klenerman D, Korchev YE. Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells. Analytical Chemistry. 85: 9333-42. PMID 24004146 DOI: 10.1021/ac4021769  0.96
2013 Clarke RW, Drews A, Browne H, Klenerman D. A single gD glycoprotein can mediate infection by Herpes simplex virus. Journal of the American Chemical Society. 135: 11175-80. PMID 23837576 DOI: 10.1021/ja4038406  0.96
2013 Shim JU, Ranasinghe RT, Smith CA, Ibrahim SM, Hollfelder F, Huck WT, Klenerman D, Abell C. Ultrarapid generation of femtoliter microfluidic droplets for single-molecule-counting immunoassays. Acs Nano. 7: 5955-64. PMID 23805985 DOI: 10.1021/nn401661d  0.96
2013 Horrocks MH, Rajah L, Jönsson P, Kjaergaard M, Vendruscolo M, Knowles TP, Klenerman D. Single-molecule measurements of transient biomolecular complexes through microfluidic dilution. Analytical Chemistry. 85: 6855-9. PMID 23782428 DOI: 10.1021/ac4010875  0.96
2013 Weimann L, Ganzinger KA, McColl J, Irvine KL, Davis SJ, Gay NJ, Bryant CE, Klenerman D. A quantitative comparison of single-dye tracking analysis tools using Monte Carlo simulations. Plos One. 8: e64287. PMID 23737978 DOI: 10.1371/journal.pone.0064287  0.96
2013 Stephenson JD, Li H, Kenyon JC, Symmons M, Klenerman D, Lever AM. Three-dimensional RNA structure of the major HIV-1 packaging signal region. Structure (London, England : 1993). 21: 951-62. PMID 23685210 DOI: 10.1016/j.str.2013.04.008  0.96
2013 Klamp T, Camps M, Nieto B, Guasch F, Ranasinghe RT, Wiedemann J, Petrášek Z, Schwille P, Klenerman D, Sauer M. Highly rapid amplification-free and quantitative DNA imaging assay Scientific Reports. 3. PMID 23677392 DOI: 10.1038/srep01852  0.96
2013 Narayan P, Ganzinger KA, McColl J, Weimann L, Meehan S, Qamar S, Carver JA, Wilson MR, St George-Hyslop P, Dobson CM, Klenerman D. Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells. Journal of the American Chemical Society. 135: 1491-8. PMID 23339742 DOI: 10.1021/ja3103567  0.96
2013 Klenerman D, Shevchuk A, Novak P, Korchev YE, Davis SJ. Imaging the cell surface and its organization down to the level of single molecules. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120027. PMID 23267181 DOI: 10.1098/rstb.2012.0027  0.96
2013 Clarke RW, Zhukov A, Richards O, Johnson N, Ostanin V, Klenerman D. Pipette-surface interaction: current enhancement and intrinsic force. Journal of the American Chemical Society. 135: 322-9. PMID 23210472 DOI: 10.1021/ja3094586  0.96
2013 Shim JU, Ranasinghe RT, Hollfelder F, Huck WTS, Klenerman D, Abell C, Cooper J. Megahertz-generated femtoliter microfluidic droplets for single-molecule-counting immunoassay 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 1: 669-671.  0.96
2012 Ye Y, Blaser G, Horrocks MH, Ruedas-Rama MJ, Ibrahim S, Zhukov AA, Orte A, Klenerman D, Jackson SE, Komander D. Ubiquitin chain conformation regulates recognition and activity of interacting proteins. Nature. 492: 266-70. PMID 23201676 DOI: 10.1038/nature11722  0.96
2012 Narayan P, Meehan S, Carver JA, Wilson MR, Dobson CM, Klenerman D. Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones Biochemistry. 51: 9270-9276. PMID 23106396 DOI: 10.1021/bi301277k  0.96
2012 Zhukov A, Richards O, Ostanin V, Korchev Y, Klenerman D. A hybrid scanning mode for fast scanning ion conductance microscopy (SICM) imaging. Ultramicroscopy. 121: 1-7. PMID 22902298 DOI: 10.1016/j.ultramic.2012.06.015  0.96
2012 Lando D, Endesfelder U, Berger H, Subramanian L, Dunne PD, McColl J, Klenerman D, Carr AM, Sauer M, Allshire RC, Heilemann M, Laue ED. Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast. Open Biology. 2: 120078. PMID 22870388 DOI: 10.1098/rsob.120078  0.96
2012 Jönsson P, McColl J, Clarke RW, Ostanin VP, Jönsson B, Klenerman D. Hydrodynamic trapping of molecules in lipid bilayers. Proceedings of the National Academy of Sciences of the United States of America. 109: 10328-33. PMID 22699491 DOI: 10.1073/pnas.1202858109  0.96
2012 Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D. Direct observation of the interconversion of normal and toxic forms of α-synuclein. Cell. 149: 1048-59. PMID 22632969 DOI: 10.1016/j.cell.2012.03.037  0.96
2012 Takahashi Y, Shevchuk AI, Novak P, Babakinejad B, Macpherson J, Unwin PR, Shiku H, Gorelik J, Klenerman D, Korchev YE, Matsue T. Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy. Proceedings of the National Academy of Sciences of the United States of America. 109: 11540-5. PMID 22611191 DOI: 10.1073/pnas.1203570109  0.96
2012 Shevchuk AI, Novak P, Taylor M, Diakonov IA, Ziyadeh-Isleem A, Bitoun M, Guicheney P, Lab MJ, Gorelik J, Merrifield CJ, Klenerman D, Korchev YE. An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy. The Journal of Cell Biology. 197: 499-508. PMID 22564416 DOI: 10.1083/jcb.201109130  0.96
2012 Narayan P, Orte A, Clarke RW, Bolognesi B, Hook S, Ganzinger KA, Meehan S, Wilson MR, Dobson CM, Klenerman D. The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β 1-40 peptide Nature Structural and Molecular Biology. 19: 79-84. PMID 22179788 DOI: 10.1038/nsmb.2191  0.96
2012 Horrocks MH, Li H, Shim JU, Ranasinghe RT, Clarke RW, Huck WT, Abell C, Klenerman D. Single molecule fluorescence under conditions of fast flow. Analytical Chemistry. 84: 179-85. PMID 22147688 DOI: 10.1021/ac202313d  0.96
2012 Ranasinghe RT, Klenerman D. Fluorophore conjugates for single molecule work Rsc Biomolecular Sciences. 34-74.  0.96
2011 Takahashi Y, Shevchuk AI, Novak P, Zhang Y, Ebejer N, Macpherson JV, Unwin PR, Pollard AJ, Roy D, Clifford CA, Shiku H, Matsue T, Klenerman D, Korchev YE. Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces. Angewandte Chemie (International Ed. in English). 50: 9638-42. PMID 21882305 DOI: 10.1002/anie.201102796  0.96
2011 Cooper MA, Dultsev FN, Ostanin VP, Klenerman D. Separation and detection of bacteria using rupture event scanning. Analytica Chimica Acta. 702: 233-8. PMID 21839203 DOI: 10.1016/j.aca.2011.06.025  0.96
2011 James JR, McColl J, Oliveira MI, Dunne PD, Huang E, Jansson A, Nilsson P, Sleep DL, Gonçalves CM, Morgan SH, Felce JH, Mahen R, Fernandes RA, Carmo AM, Klenerman D, et al. The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins. The Journal of Biological Chemistry. 286: 31993-2001. PMID 21757710 DOI: 10.1074/jbc.M111.219212  0.96
2011 Shevchuk AI, Novak P, Takahashi Y, Clarke R, Miragoli M, Babakinejad B, Gorelik J, Korchev YE, Klenerman D. Realizing the biological and biomedical potential of nanoscale imaging using a pipette probe. Nanomedicine (London, England). 6: 565-75. PMID 21542692 DOI: 10.2217/nnm.10.154  0.96
2011 Klenerman D, Korchev YE, Davis SJ. Imaging and characterisation of the surface of live cells. Current Opinion in Chemical Biology. 15: 696-703. PMID 21536476 DOI: 10.1016/j.cbpa.2011.04.001  0.96
2011 Miragoli M, Moshkov A, Novak P, Shevchuk A, Nikolaev VO, El-Hamamsy I, Potter CM, Wright P, Kadir SH, Lyon AR, Mitchell JA, Chester AH, Klenerman D, Lab MJ, Korchev YE, et al. Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells. Journal of the Royal Society, Interface / the Royal Society. 8: 913-25. PMID 21325316 DOI: 10.1098/rsif.2010.0597  0.96
2011 Zhou D, Li Y, Hall EA, Abell C, Klenerman D. A chelating dendritic ligand capped quantum dot: preparation, surface passivation, bioconjugation and specific DNA detection. Nanoscale. 3: 201-11. PMID 21046040 DOI: 10.1039/c0nr00462f  0.96
2011 Orte A, Clarke RW, Klenerman D. Single-molecule fluorescence coincidence spectroscopy and its application to resonance energy transfer. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 12: 491-9. PMID 20922742 DOI: 10.1002/cphc.201000636  0.96
2010 Orte A, Clarke R, Klenerman D. Single-molecule two-colour coincidence detection to probe biomolecular associations. Biochemical Society Transactions. 38: 914-8. PMID 20658976 DOI: 10.1042/BST0380914  0.96
2010 Bruckbauer A, Dunne PD, James P, Howes E, Zhou D, Jones R, Klenerman D. Selective diffusion barriers separate membrane compartments. Biophysical Journal. 99: L1-3. PMID 20655822 DOI: 10.1016/j.bpj.2010.03.067  0.96
2010 Yeoman JA, Orte A, Ashbridge B, Klenerman D, Balasubramanian S. RNA conformation in catalytically active human telomerase. Journal of the American Chemical Society. 132: 2852-3. PMID 20148555 DOI: 10.1021/ja909383n  0.96
2010 Jones R, Howes E, Dunne PD, James P, Bruckbauer A, Klenerman D. Tracking diffusion of GM1 gangliosides and zona pellucida binding molecules in sperm plasma membranes following cholesterol efflux. Developmental Biology. 339: 398-406. PMID 20060391 DOI: 10.1016/j.ydbio.2009.12.044  0.96
2010 van der Merwe PA, Dunne PD, Klenerman D, Davis SJ. Taking T cells beyond the diffraction limit. Nature Immunology. 11: 51-2. PMID 20016513 DOI: 10.1038/ni0110-51  0.96
2009 Chiou A, Hägglöf P, Orte A, Chen AY, Dunne PD, Belorgey D, Karlsson-Li S, Lomas DA, Klenerman D. Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence. Biophysical Journal. 97: 2306-15. PMID 19843463 DOI: 10.1016/j.bpj.2009.07.057  0.96
2009 Ashbridge B, Orte A, Yeoman JA, Kirwan M, Vulliamy T, Dokal I, Klenerman D, Balasubramanian S. Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations. Biochemistry. 48: 10858-65. PMID 19835419 DOI: 10.1021/bi901373e  0.96
2009 Dunne PD, Fernandes RA, McColl J, Yoon JW, James JR, Davis SJ, Klenerman D. DySCo: quantitating associations of membrane proteins using two-color single-molecule tracking. Biophysical Journal. 97: L5-7. PMID 19686638 DOI: 10.1016/j.bpj.2009.05.046  0.96
2009 Shivji MK, Mukund SR, Rajendra E, Chen S, Short JM, Savill J, Klenerman D, Venkitaraman AR. The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange. Proceedings of the National Academy of Sciences of the United States of America. 106: 13254-9. PMID 19628690 DOI: 10.1073/pnas.0906208106  0.96
2009 Novak P, Li C, Shevchuk AI, Stepanyan R, Caldwell M, Hughes S, Smart TG, Gorelik J, Ostanin VP, Lab MJ, Moss GW, Frolenkov GI, Klenerman D, Korchev YE. Nanoscale live-cell imaging using hopping probe ion conductance microscopy. Nature Methods. 6: 279-81. PMID 19252505 DOI: 10.1038/nmeth.1306  0.96
2008 Gorelik J, Ali NN, Sheikh Abdul Kadir SH, Lab M, Stojkovic P, Armstrong L, Sviderskaya EV, Negulyaev YA, Klenerman D, Bennett DC, Lako M, Harding SE, Stojkovic M, Korchev YE. Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective. Tissue Engineering. Part C, Methods. 14: 311-8. PMID 19055357 DOI: 10.1089/ten.tec.2008.0058  0.96
2008 Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR, Boutell JM, Bryant J, Carter RJ, Keira Cheetham R, Cox AJ, ... ... Klenerman D, et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature. 456: 53-9. PMID 18987734 DOI: 10.1038/nature07517  0.68
2008 Orte A, Clarke RW, Klenerman D. Fluorescence coincidence spectroscopy for single-molecule fluorescence resonance energy-transfer measurements. Analytical Chemistry. 80: 8389-97. PMID 18855410 DOI: 10.1021/ac8009092  0.96
2008 Orte A, Birkett NR, Clarke RW, Devlin GL, Dobson CM, Klenerman D. Direct characterization of amyloidogenic oligomers by single-molecule fluorescence. Proceedings of the National Academy of Sciences of the United States of America. 105: 14424-9. PMID 18796612 DOI: 10.1073/pnas.0803086105  0.96
2008 Piper JD, Li C, Lo CJ, Berry R, Korchev Y, Ying L, Klenerman D. Characterization and application of controllable local chemical changes produced by reagent delivery from a nanopipet. Journal of the American Chemical Society. 130: 10386-93. PMID 18624405 DOI: 10.1021/ja8022253  0.96
2008 Sánchez D, Johnson N, Li C, Novak P, Rheinlaender J, Zhang Y, Anand U, Anand P, Gorelik J, Frolenkov GI, Benham C, Lab M, Ostanin VP, Schäffer TE, Klenerman D, et al. Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette. Biophysical Journal. 95: 3017-27. PMID 18515369 DOI: 10.1529/biophysj.108.129551  0.96
2008 Orte A, Craggs TD, White SS, Jackson SE, Klenerman D. Evidence of an intermediate and parallel pathways in protein unfolding from single-molecule fluorescence Journal of the American Chemical Society. 130: 7898-7907. PMID 18507381 DOI: 10.1021/ja709973m  0.96
2008 Alves D, Li H, Codrington R, Orte A, Ren X, Klenerman D, Balasubramanian S. Single-molecule analysis of human telomerase monomer. Nature Chemical Biology. 4: 287-9. PMID 18391947 DOI: 10.1038/nchembio.82  0.96
2008 Yoon JW, Bruckbauer A, Fitzgerald WJ, Klenerman D. Bayesian inference for improved single molecule fluorescence tracking. Biophysical Journal. 94: 4932-47. PMID 18339757 DOI: 10.1529/biophysj.107.116285  0.96
2008 Shevchuk AI, Hobson P, Lab MJ, Klenerman D, Krauzewicz N, Korchev YE. Imaging single virus particles on the surface of cell membranes by high-resolution scanning surface confocal microscopy. Biophysical Journal. 94: 4089-94. PMID 18199668 DOI: 10.1529/biophysj.107.112524  0.96
2008 Zhou D, Ying L, Hong X, Hall EA, Abell C, Klenerman D. A compact functional quantum Dot-DNA conjugate: preparation, hybridization, and specific label-free DNA detection. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 1659-64. PMID 18193909 DOI: 10.1021/la703583u  0.96
2008 Shevchuk AI, Hobson P, Lab MJ, Klenerman D, Krauzewicz N, Korchev YE. Endocytic pathways: combined scanning ion conductance and surface confocal microscopy study. PflüGers Archiv : European Journal of Physiology. 456: 227-35. PMID 18180951 DOI: 10.1007/s00424-007-0410-4  0.96
2008 Li C, Johnson N, Ostanin V, Shevchuk A, Ying L, Korchev Y, Klenerman D. High resolution imaging using scanning ion conductance microscopy with improved distance feedback control Progress in Natural Science. 18: 671-677. DOI: 10.1016/j.pnsc.2008.01.011  0.96
2008 Zhang Y, Ma L, Xu B, Gorelik J, Klenerman D, Lab M, Edwards C, Korchev Y. PI3K-mediated epithelial sodium channel activity by regulating the apical membrane morphology of renal epithelial cells Ifmbe Proceedings. 19: 603-607. DOI: 10.1007/978-3-540-79039-6-151  0.96
2007 James JR, White SS, Clarke RW, Johansen AM, Dunne PD, Sleep DL, Fitzgerald WJ, Davis SJ, Klenerman D. Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 17662-7. PMID 17971442 DOI: 10.1073/pnas.0700411104  0.96
2007 Clarke RW, Piper JD, Ying L, Klenerman D. Surface conductivity of biological macromolecules measured by nanopipette dielectrophoresis. Physical Review Letters. 98: 198102. PMID 17677664 DOI: 10.1103/PhysRevLett.98.198102  0.96
2007 Bruckbauer A, James P, Zhou D, Yoon JW, Excell D, Korchev Y, Jones R, Klenerman D. Nanopipette delivery of individual molecules to cellular compartments for single-molecule fluorescence tracking. Biophysical Journal. 93: 3120-31. PMID 17631532 DOI: 10.1529/biophysj.107.104737  0.96
2007 Jones R, James PS, Howes L, Bruckbauer A, Klenerman D. Supramolecular organization of the sperm plasma membrane during maturation and capacitation. Asian Journal of Andrology. 9: 438-44. PMID 17589780 DOI: 10.1111/j.1745-7262.2007.00282.x  0.96
2007 Clarke RW, Monnier N, Li H, Zhou D, Browne H, Klenerman D. Two-color fluorescence analysis of individual virions determines the distribution of the copy number of proteins in herpes simplex virus particles. Biophysical Journal. 93: 1329-37. PMID 17513380 DOI: 10.1529/biophysj.107.106351  0.96
2007 Zhang Y, Sanchez D, Gorelik J, Klenerman D, Lab M, Edwards C, Korchev Y. Basolateral P2X4-like receptors regulate the extracellular ATP-stimulated epithelial Na+ channel activity in renal epithelia. American Journal of Physiology. Renal Physiology. 292: F1734-40. PMID 17356127 DOI: 10.1152/ajprenal.00382.2006  0.96
2007 Clarke RW, Orte A, Klenerman D. Optimized threshold selection for single-molecule two-color fluorescence coincidence spectroscopy. Analytical Chemistry. 79: 2771-7. PMID 17343363 DOI: 10.1021/ac062188w  0.96
2007 Sánchez D, Anand U, Gorelik J, Benham CD, Bountra C, Lab M, Klenerman D, Birch R, Anand P, Korchev Y. Localized and non-contact mechanical stimulation of dorsal root ganglion sensory neurons using scanning ion conductance microscopy. Journal of Neuroscience Methods. 159: 26-34. PMID 16887195 DOI: 10.1016/j.jneumeth.2006.06.018  0.96
2006 Klenerman D, Korchev Y. Potential biomedical applications of the scanned nanopipette. Nanomedicine (London, England). 1: 107-14. PMID 17716213 DOI: 10.2217/17435889.1.1.107  0.96
2006 Piper JD, Clarke RW, Korchev YE, Ying L, Klenerman D. A renewable nanosensor based on a glass nanopipette. Journal of the American Chemical Society. 128: 16462-3. PMID 17177370 DOI: 10.1021/ja0650899  0.96
2006 Orte A, Clarke R, Balasubramanian S, Klenerman D. Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. Analytical Chemistry. 78: 7707-15. PMID 17105162 DOI: 10.1021/ac061122y  0.96
2006 Gavory G, Symmons MF, Krishnan Ghosh Y, Klenerman D, Balasubramanian S. Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. Biochemistry. 45: 13304-11. PMID 17073451 DOI: 10.1021/bi061150a  0.96
2006 White SS, Balasubramanian S, Klenerman D, Ying L. A simple nanomixer for single-molecule kinetics measurements. Angewandte Chemie (International Ed. in English). 45: 7540-3. PMID 17051625 DOI: 10.1002/anie.200602289  0.96
2006 White SS, Li H, Marsh RJ, Piper JD, Leonczek ND, Nicolaou N, Bain AJ, Ying L, Klenerman D. Characterization of a single molecule DNA switch in free solution. Journal of the American Chemical Society. 128: 11423-32. PMID 16939265 DOI: 10.1021/ja0614870  0.96
2006 Green JJ, Ladame S, Ying L, Klenerman D, Balasubramanian S. Investigating a quadruplex-ligand interaction by unfolding kinetics. Journal of the American Chemical Society. 128: 9809-12. PMID 16866537 DOI: 10.1021/ja0615425  0.96
2006 Li H, Zhou D, Browne H, Klenerman D. Evidence for resonance optical trapping of individual fluorophore-labeled antibodies using single molecule fluorescence spectroscopy. Journal of the American Chemical Society. 128: 5711-7. PMID 16637638 DOI: 10.1021/ja056997t  0.96
2006 Rauf S, Zhou D, Abell C, Klenerman D, Kang DJ. Building three-dimensional nanostructures with active enzymes by surface templated layer-by-layer assembly. Chemical Communications (Cambridge, England). 1721-3. PMID 16609783 DOI: 10.1039/b517557g  0.96
2006 Ren X, Li H, Clarke RW, Alves DA, Ying L, Klenerman D, Balasubramanian S. Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. Journal of the American Chemical Society. 128: 4992-5000. PMID 16608333 DOI: 10.1021/ja056613z  0.96
2006 Manzanera M, Frankel DJ, Li H, Zhou D, Bruckbauer A, Kreutzmann P, Blackburn JM, Abell C, Rayment T, Klenerman D, Barker PD. Macroscopic 2D networks self-assembled from nanometer-sized protein/DNA complexes. Nano Letters. 6: 365-70. PMID 16522024 DOI: 10.1021/nl051599+  0.96
2006 Shevchuk AI, Frolenkov GI, Sánchez D, James PS, Freedman N, Lab MJ, Jones R, Klenerman D, Korchev YE. Imaging proteins in membranes of living cells by high-resolution scanning ion conductance microscopy. Angewandte Chemie (International Ed. in English). 45: 2212-6. PMID 16506257 DOI: 10.1002/anie.200503915  0.96
2006 Liu D, Bruckbauer A, Abell C, Balasubramanian S, Kang DJ, Klenerman D, Zhou D. A reversible pH-driven DNA nanoswitch array. Journal of the American Chemical Society. 128: 2067-71. PMID 16464109 DOI: 10.1021/ja0568300  0.96
2006 Rodolfa KT, Bruckbauer A, Zhou D, Schevchuk AI, Korchev YE, Klenerman D. Nanoscale pipetting for controlled chemistry in small arrayed water droplets using a double-barrel pipet. Nano Letters. 6: 252-7. PMID 16464045 DOI: 10.1021/nl052215i  0.96
2005 Rodolfa KT, Bruckbauer A, Zhou D, Korchev YE, Klenerman D. Two-component graded deposition of biomolecules with a double-barreled nanopipette. Angewandte Chemie (International Ed. in English). 44: 6854-9. PMID 16249993 DOI: 10.1002/anie.200502338  0.96
2005 Gorelik J, Zhang Y, Sánchez D, Shevchuk A, Frolenkov G, Lab M, Klenerman D, Edwards C, Korchev Y. Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited. Proceedings of the National Academy of Sciences of the United States of America. 102: 15000-5. PMID 16230642 DOI: 10.1073/pnas.0507008102  0.96
2005 Zhou D, Piper JD, Abell C, Klenerman D, Kang DJ, Ying L. Fluorescence resonance energy transfer between a quantum dot donor and a dye acceptor attached to DNA. Chemical Communications (Cambridge, England). 4807-9. PMID 16193121 DOI: 10.1039/b508911e  0.96
2005 Ying L, Bruckbauer A, Zhou D, Gorelik J, Shevchuk A, Lab M, Korchev Y, Klenerman D. The scanned nanopipette: a new tool for high resolution bioimaging and controlled deposition of biomolecules. Physical Chemistry Chemical Physics : Pccp. 7: 2859-66. PMID 16189604 DOI: 10.1039/b506743j  0.96
2005 Zhang Y, Gorelik J, Sanchez D, Shevchuk A, Lab M, Vodyanoy I, Klenerman D, Edwards C, Korchev Y. Scanning ion conductance microscopy reveals how a functional renal epithelial monolayer maintains its integrity. Kidney International. 68: 1071-7. PMID 16105037 DOI: 10.1111/j.1523-1755.2005.00499.x  0.96
2005 Clarke RW, White SS, Zhou D, Ying L, Klenerman D. Trapping of proteins under physiological conditions in a nanopipette. Angewandte Chemie (International Ed. in English). 44: 3747-50. PMID 15883978 DOI: 10.1002/anie.200500196  0.96
2005 Zhou D, Bruckbauer A, Abell C, Klenerman D, Kang DJ. Fabrication of three-dimensional surface structures with highly fluorescent quantum dots by surface-templated layer-by-layer assembly Advanced Materials. 17: 1243-1248. DOI: 10.1002/adma.200401520  0.96
2004 White SS, Ying L, Balasubramanian S, Klenerman D. Individual molecules of dye-labeled DNA act as a reversible two-color switch upon application of an electric field. Angewandte Chemie (International Ed. in English). 43: 5926-30. PMID 15547896 DOI: 10.1002/anie.200460323  0.96
2004 Li H, Ying L, Ren X, Balasubramanian S, Klenerman D. Fluorescence studies of single biomolecules. Biochemical Society Transactions. 32: 753-6. PMID 15494006 DOI: 10.1042/BST0320753  0.96
2004 Zhou D, Bruckbauer A, Batchelor M, Kang DJ, Abell C, Klenerman D. Influence of the foundation layer on the layer-by-layer assembly of poly-L-lysine and poly(styrenesulfonate) and its usage in the fabrication of 3D microscale features. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 9089-94. PMID 15461491 DOI: 10.1021/la048619s  0.96
2004 Li H, Ren X, Ying L, Balasubramanian S, Klenerman D. Measuring single-molecule nucleic acid dynamics in solution by two-color filtered ratiometric fluorescence correlation spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 101: 14425-30. PMID 15452356 DOI: 10.1073/pnas.0404295101  0.96
2004 Li H, Zhou D, Browne H, Balasubramanian S, Klenerman D. Molecule by molecule direct and quantitative counting of antibody-protein complexes in solution. Analytical Chemistry. 76: 4446-51. PMID 15283586 DOI: 10.1021/ac049512c  0.96
2004 Bruckbauer A, Zhou D, Kang DJ, Korchev YE, Abell C, Klenerman D. An addressable antibody nanoarray produced on a nanostructured surface. Journal of the American Chemical Society. 126: 6508-9. PMID 15161251 DOI: 10.1021/ja0317426  0.96
2004 Gorelik J, Zhang Y, Shevchuk AI, Frolenkov GI, Sánchez D, Lab MJ, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. The use of scanning ion conductance microscopy to image A6 cells. Molecular and Cellular Endocrinology. 217: 101-8. PMID 15134807 DOI: 10.1016/j.mce.2003.10.015  0.96
2004 Ying L, White SS, Bruckbauer A, Meadows L, Korchev YE, Klenerman D. Frequency and voltage dependence of the dielectrophoretic trapping of short lengths of DNA and dCTP in a nanopipette. Biophysical Journal. 86: 1018-27. PMID 14747337 DOI: 10.1016/S0006-3495(04)74177-6  0.96
2004 Bruckbauer A, Zhou D, Ying L, Abell C, Klenerman D. A simple voltage controlled enzymatic nanoreactor produced in the tip of a nanopipet Nano Letters. 4: 1859-1862. DOI: 10.1021/nl049029h  0.96
2004 Petersen AG, Klenerman D, Hedges WM. Evaluation of the effect of carbon dioxide corrosion inhibitors on cavitation damage caused during the ultrasound test Corrosion. 60: 187-194.  0.96
2003 Wang JH, Klenerman D, Van Der Pol A, Meier RJ. Surface-sensitive molecular information on polymers from UV-resonance Raman spectroscopy Applied Spectroscopy. 57: 518-521. PMID 14658676 DOI: 10.1366/000370203321666524  0.96
2003 Ying L, Green JJ, Li H, Klenerman D, Balasubramanian S. Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 100: 14629-34. PMID 14645716 DOI: 10.1073/pnas.2433350100  0.96
2003 Ren X, Gavory G, Li H, Ying L, Klenerman D, Balasubramanian B. Identification of a new RNA·RNA interaction site for human telomerase RNA (hTR): Structural implications for hTR accumulation and a dyskeratosis congenita point mutation Nucleic Acids Research. 31: 6509-6515. PMID 14602909 DOI: 10.1093/nar/gkg871  0.96
2003 Bruckbauer A, Zhou D, Ying L, Korchev YE, Abell C, Klenerman D. Multicomponent submicron features of biomolecules created by voltage controlled deposition from a nanopipet. Journal of the American Chemical Society. 125: 9834-9. PMID 12904050 DOI: 10.1021/ja035755v  0.96
2003 Gorelik J, Shevchuk AI, Frolenkov GI, Diakonov IA, Lab MJ, Kros CJ, Richardson GP, Vodyanoy I, Edwards CR, Klenerman D, Korchev YE. Dynamic assembly of surface structures in living cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 5819-22. PMID 12721367 DOI: 10.1073/pnas.1030502100  0.96
2003 Berg O, Klenerman D. Vibrational spectroscopy of mechanically compressed monolayers Journal of the American Chemical Society. 125: 5493-5500. PMID 12720464 DOI: 10.1021/ja027128w  0.96
2003 Li H, Ying L, Green JJ, Balasubramanian S, Klenerman D. Ultrasensitive coincidence fluorescence detection of single DNA molecules. Analytical Chemistry. 75: 1664-70. PMID 12705600 DOI: 10.1021/ac026367z  0.96
2003 Green JJ, Ying L, Klenerman D, Balasubramanian S. Kinetics of unfolding the human telomeric DNA quadruplex using a PNA trap. Journal of the American Chemical Society. 125: 3763-7. PMID 12656607 DOI: 10.1021/ja029149w  0.96
2003 Rothery AM, Gorelik J, Bruckbauer A, Yu W, Korchev YE, Klenerman D. A novel light source for SICM-SNOM of living cells Journal of Microscopy. 209: 94-101. PMID 12588526 DOI: 10.1046/j.1365-2818.2003.01122.x  0.96
2003 Zhou D, Bruckbauer A, Ying L, Abell C, Klenerman D. Building Three-Dimensional Surface Biological Assemblies on the Nanometer Scale Nano Letters. 3: 1517-1520. DOI: 10.1021/nl0345926  0.96
2002 Gorelik J, Gu Y, Spohr HA, Shevchuk AI, Lab MJ, Harding SE, Edwards CR, Whitaker M, Moss GW, Benton DC, Sánchez D, Darszon A, Vodyanoy I, Klenerman D, Korchev YE. Ion channels in small cells and subcellular structures can be studied with a smart patch-clamp system. Biophysical Journal. 83: 3296-303. PMID 12496097 DOI: 10.1016/S0006-3495(02)75330-7  0.96
2002 Gorelik J, Shevchuk A, Ramalho M, Elliott M, Lei C, Higgins CF, Lab MJ, Klenerman D, Krauzewicz N, Korchev Y. Scanning surface confocal microscopy for simultaneous topographical and fluorescence imaging: Application to single virus-like particle entry into a cell Proceedings of the National Academy of Sciences of the United States of America. 99: 16018-16023. PMID 12466501 DOI: 10.1073/pnas.252458399  0.96
2002 Bruckbauer A, Ying L, Rothery AM, Zhou D, Shevchuk AI, Abell C, Korchev YE, Klenerman D. Writing with DNA and protein using a nanopipet for controlled delivery. Journal of the American Chemical Society. 124: 8810-1. PMID 12137530 DOI: 10.1021/ja026816c  0.96
2002 Bruckbauer A, Ying L, Rothery AM, Korchev YE, Klenerman D. Characterization of a novel light source for simultaneous optical and scanning ion conductance microscopy Analytical Chemistry. 74: 2612-2616. PMID 12069246 DOI: 10.1021/ac011257y  0.96
2002 Gu Y, Gorelik J, Spohr HA, Shevchuk A, Lab MJ, Harding SE, Vodyanoy I, Klenerman D, Korchev YE. High-resolution scanning patch-clamp: new insights into cell function The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 748-750. PMID 11923226  0.96
2002 Ying L, Bruckbauer A, Rothery AM, Korchev YE, Klenerman D. Programmable delivery of DNA through a nanopipet Analytical Chemistry. 74: 1380-1385. PMID 11922307 DOI: 10.1021/ac015674m  0.96
2002 Cooper MA, Ostanin VP, Klenerman D, Slepstov A, Karamanska R, Dultsev FN, Stirrups K, Kelling S, Minson T, Abell C. A Sensitive and Economical Method to Directly Detect Particles Proceedings of Ieee Sensors. 1: 1042-1045.  0.96
2002 Green J, Ying L, Klenerman D, Blasubramanian S. Single-molecule FRET study of DNA G-quadruplex Chemical Research in Chinese Universities. 18: 103-106.  0.96
2002 Petersen AG, Klenerman D, Hedges WM, Harris ML. Effect of cavitation on carbon dioxide corrosion and the development of a test for evaluating inhibitors Corrosion. 58: 216-224.  0.96
2002 Kelling S, Cooper MA, Stirrups K, Karamanska R, Ostanin VP, Klenerman D, Slepstov A, Rehak M, Dultsev FN, Minson T, Abell C. Sensitive and direct detection using rupture event scanning (REVS™) Proceedings of the Annual Ieee International Frequency Control Symposium. 756-759.  0.96
2001 Dultsev FN, Speight RE, Fiorini MT, Blackburn JM, Abell C, Ostanin VP, Klenerman D. Direct and quantitative detection of bacteriophage by "hearing" surface detachment using a quartz crystal microbalance. Analytical Chemistry. 73: 3935-9. PMID 11534719 DOI: 10.1021/ac0100897  0.96
2001 Cooper MA, Dultsev FN, Minson T, Ostanin VP, Abell C, Klenerman D. Direct and sensitive detection of a human virus by rupture event scanning Nature Biotechnology. 19: 833-837. PMID 11533641 DOI: 10.1038/nbt0901-833  0.96
2001 Shevchuk AI, Gorelik J, Harding SE, Lab MJ, Klenerman D, Korchev YE. Simultaneous measurement of Ca2+ and cellular dynamics: Combined scanning ion conductance and optical microscopy to study contracting cardiac myocytes Biophysical Journal. 81: 1759-1764. PMID 11509385  0.96
2001 Wallace MI, Ying L, Balasubramanian S, Klenerman D. Non-arrhenius kinetics for the loop closure of a DNA hairpin Proceedings of the National Academy of Sciences of the United States of America. 98: 5584-5589. PMID 11320222 DOI: 10.1073/pnas.101523498  0.96
2001 Berg O, Klenerman D. Effects of mechanical compression on the vibrational spectrum of a self-assembled monolayer Journal of Applied Physics. 90: 5070-5074. DOI: 10.1063/1.1407850  0.96
2001 Ying L, Wallace MI, Klenerman D. Two-state model of conformational fluctuation in a DNA hairpin-loop Chemical Physics Letters. 334: 145-150. DOI: 10.1016/S0009-2614(00)01425-1  0.96
2001 Osborne MA, Barnes CL, Balasubramanian S, Klenerman D. Probing DNA surface attachment and local environment using single molecule spectroscopy Journal of Physical Chemistry B. 105: 3120-3126.  0.96
2000 Osborne MA, Furey WS, Klenerman D, Balasubramanian S. Single-molecule analysis of DNA immobilized on microspheres. Analytical Chemistry. 72: 3678-81. PMID 10952560  0.96
2000 Korchev YE, Raval M, Lab MJ, Gorelik J, Edwards CR, Rayment T, Klenerman D. Hybrid scanning ion conductance and scanning near-field optical microscopy for the study of living cells. Biophysical Journal. 78: 2675-9. PMID 10777763 DOI: 10.1016/S0006-3495(00)76811-1  0.96
2000 Dultsev FN, Ostanin VP, Klenerman D. 'Hearing' bond breakage. Measurement of bond rupture forces using a quartz crystal microbalance Langmuir. 16: 5036-5040. DOI: 10.1021/la990789v  0.96
2000 Heeg B, Klenerman D. Model corrosion inhibitor for in situ spectroscopic studies Langmuir. 16: 1783-1792. DOI: 10.1021/la981617l  0.96
2000 Lin S, Oldfield A, Klenerman D. In-situ studies of polycrystalline copper during methanol synthesis at high pressure using sum frequency generation at surfaces Surface Science. 464: 1-7. DOI: 10.1016/S0039-6028(00)00706-8  0.96
2000 Wallace ML, Ying L, Balasubramanian S, Klenerman D. FRET fluctuation spectroscopy: Exploring the conformational dynamics of a DNA hairpin loop Journal of Physical Chemistry B. 104: 11551-11555.  0.96
2000 Ying L, Wallace MI, Balasubramanian S, Klenerman D. Ratiometric Analysis of Single-Molecule Fluorescence Resonance Energy Transfer Using Logical Combinations of Threshold Criteria: A Study of 12-mer DNA Journal of Physical Chemistry B. 104: 5171-5178.  0.96
1999 Hutchison J, Klenerman D, Manning-Benson S, Bain C. Measurements of the adsorption kinetics of a cationic surfactant in a liquid jet by ellipsometry Langmuir. 15: 7530-7533. DOI: 10.1021/la9901480  0.96
1998 Couling VW, Fischer P, Klenerman D, Huber W. Ultraviolet resonance Raman study of drug binding in dihydrofolate reductase, gyrase, and catechol O-methyltransferase Biophysical Journal. 75: 1097-1106. PMID 9675211  0.96
1998 Keller TH, Rayment T, Klenerman D. Optical chemical imaging of tobacco mosaic virus in solution at 60-nm resolution Biophysical Journal. 74: 2076-2079. PMID 9545066  0.96
1998 Furey WS, Joyce CM, Osborne MA, Klenerman D, Peliska JA, Balasubramanian S. Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment. Biochemistry. 37: 2979-90. PMID 9485450 DOI: 10.1021/bi9719758  0.96
1998 Heeg B, Klenerman D. Persistency of corrosion inhibitor films on C-steel under multiphase flow conditions. Part II: optical SHG and electrochemical studies Corrosion Science. 40: 1313-1329. DOI: 10.1016/S0010-938X(98)00013-4  0.96
1998 Heeg B, Moros T, Klenerman D. Persistency of corrosion inhibitor films on C-steel under multiphase flow conditions. Part I: the jet-cylinder arrangement Corrosion Science. 40: 1303-1311. DOI: 10.1016/S0010-938X(98)00012-2  0.96
1998 Duffy DC, Friedmann A, Boggis SA, Klenerman D. Surface vibrational spectroscopy of lubricants adsorbed at the iron-water interface Langmuir. 14: 6518-6527.  0.96
1998 Osborne MA, Balasubramanian S, Furey WS, Klenerman D. Optically biased diffusion of single molecules studied by confocal fluorescence microscopy Journal of Physical Chemistry B. 102: 3160-3167.  0.96
1997 Couling VW, Foster NW, Klenerman D. Ultraviolet resonance Raman spectroscopic study of the average environment of tyrosine in native and denatured barnase Journal of Raman Spectroscopy. 28: 33-38.  0.96
1997 Keller TH, Rayment T, Klenerman D, Stephenson RJ. Scanning near-field optical microscopy in reflection mode imaging in liquid Review of Scientific Instruments. 68: 1448-1454.  0.96
1994 Edwards A, Osborne C, Webster S, Klenerman D, Joseph M, Ostovar P, Doyle M. Mechanistic studies of the corrosion inhibitor oleic imidazoline Corrosion Science. 36: 315-325. DOI: 10.1016/0010-938X(94)90160-0  0.96
1994 Klenerman D, Hodge J, Joseph M. Second harmonic generation at surfaces applied to corrosion inhibition Corrosion Science. 36: 301-313. DOI: 10.1016/0010-938X(94)90159-7  0.96
1993 Maechling CR, Kliner DAV, Klenerman D. Sum frequency spectra in the C-H stretch region of adsorbates on iron Applied Spectroscopy. 47: 167-172. DOI: 10.1366/0003702934048361  0.96
1992 Joseph M, Hodge J, Klenerman D. Studies of the adsorption of a corrosion inhibitor onto mild steel using surface second-harmonic generation Faraday Discussions. 94: 273-281. DOI: 10.1039/FD9929400273  0.96
1992 Joseph M, Klenerman D. A second-harmonic generation study of a corrosion inhibitor on a mild steel electrode Journal of Electroanalytical Chemistry. 340: 301-313. DOI: 10.1016/0022-0728(92)80305-N  0.96
1991 Klenerman D, Spowage K, Walpole B. Second harmonic generation (SHG) as an in situ diagnostic for corrosion Proceedings of Spie - the International Society For Optical Engineering. 1437: 95-102.  0.96
1990 Klenerman D, Gerrard DL, Herman H, MacPherson MT. Optically heterodyned Raman-induced Kerr-effect spectroscopy using a white-light continuum Chemical Physics Letters. 168: 579-583. DOI: 10.1016/0009-2614(90)85675-3  0.96
1988 Gutow JH, Klenerman D, Zare RN. Comparison of overtone-induced and electronic photochemistry of liquid tert-butyl hydroperoxide: Supporting evidence for vibrational mode selectivity Journal of Physical Chemistry. 92: 172-177.  0.96
1988 Crofton MW, Stevens CG, Klenerman D, Gutow JH, Zare RN. Overtone spectra of C-H oscillators in cold molecules The Journal of Chemical Physics. 89: 7100-7111.  0.96
1987 Klenerman D, Smith IWM. Infrared chemiluminescence using a SISAM spectrometer. Reactions producing vibrationally excited HF Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics. 83: 243-254. DOI: 10.1039/F29878300243  0.96
1987 Klenerman D, Smith IWM. Infrared chemiluminescence studies using a SISAM spectrometer. Reactions producing vibrationally excited OH Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics. 83: 229-241. DOI: 10.1039/F29878300229  0.96
1986 Klenerman D, Zare RN. How effective is internal excitation in promoting the HCl + 1,3-butadiene addition reaction? Chemical Physics Letters. 130: 190-194. DOI: 10.1016/0009-2614(86)80452-3  0.96
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