Joseph E. Pero, Ph.D. - Publications

Affiliations: 
2006 University of Rochester, Rochester, NY 
Area:
Synthetic Organic Chemistry

1/12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Boeckman RK, Song X, Pero JE. Facile preparation and functionalization of chiral stabilized ylides from common chiral auxiliaries using triphenyl- phosphoranylideneketene (the Bestmann ylide) and their use in Wittig reactions. The Journal of Organic Chemistry. 71: 8969-72. PMID 17081033 DOI: 10.1021/jo061732y  0.644
Low-probability matches (unlikely to be authored by this person)
2011 Marcoux D, Bindschädler P, Speed AW, Chiu A, Pero JE, Borg GA, Evans DA. Effect of counterion structure on rates and diastereoselectivities in α,β-unsaturated iminium-ion Diels-Alder reactions. Organic Letters. 13: 3758-61. PMID 21678927 DOI: 10.1021/Ol201448H  0.298
2016 Pero JE, Rossi MA, Kelly MJ, Lehman HD, Layton ME, Garbaccio RM, O'Brien JA, Magliaro BC, Uslaner JM, Huszar SL, Fillgrove KL, Tang C, Kuo Y, Joyce LA, Sherer EC, et al. Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. Acs Medicinal Chemistry Letters. 7: 312-7. PMID 26985321 DOI: 10.1021/Acsmedchemlett.5B00459  0.184
2017 Pero JE, Rossi MA, Lehman HDGF, Kelly MJ, Mulhearn JJ, Wolkenberg SE, Cato MJ, Clements MK, Daley CJ, Filzen T, Finger EN, Gregan Y, Henze DA, Jovanovska A, Klein R, et al. Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model. Bioorganic & Medicinal Chemistry Letters. PMID 28465103 DOI: 10.1016/J.Bmcl.2017.04.040  0.116
2021 Pero JE, McAtee JJ, Behm DJ, Briand J, Graczyk-Millbrandt G, Erhard K, Roberts AD, Rivero RA, Holt DA, Lawhorn BG. Identification, Synthesis, and Characterization of a Major Circulating Human Metabolite of TRPV4 Antagonist GSK2798745. Acs Medicinal Chemistry Letters. 12: 1498-1502. PMID 34531959 DOI: 10.1021/acsmedchemlett.1c00406  0.104
2006 Boeckman RK, Pero JE, Boehmler DJ. Toward the development of a general chiral auxiliary. Enantioselective alkylation and a new catalytic asymmetric addition of silyloxyfurans: application to a total synthesis of (-)-rasfonin. Journal of the American Chemical Society. 128: 11032-3. PMID 16925414 DOI: 10.1021/ja063532+  0.098
2018 Pero JE, Matthews J, Behm DJ, Brnardic E, Brooks CA, Budzik BW, Costell M, Donatelli C, Eisennagel S, Erhard KF, Fischer M, Holt DA, Jolivette L, Li H, Li P, et al. Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4) with In Vivo Activity in a Pulmonary Edema Model. Journal of Medicinal Chemistry. PMID 30500190 DOI: 10.1021/Acs.Jmedchem.8B01344  0.07
2016 Woolford AJ, Pero JE, Aravapalli S, Berdini V, Coyle JE, Day PJ, Dodson AM, Grondin P, Holding FP, Lee LY, Li P, Manas ES, Marino JP, Martin AC, McCleland BW, et al. Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening. Journal of Medicinal Chemistry. PMID 27167608 DOI: 10.1021/acs.jmedchem.6b00212  0.057
2019 Brooks CA, Barton LS, Behm DJ, Brnardic E, Costell M, Holt DA, Jolivette LJ, Matthews JM, McAtee JJ, McCleland BW, Patterson JR, Pero JE, Rivero RA, Roethke TJ, Sanchez RM, et al. Discovery of GSK3527497: A candidate for the inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4). Journal of Medicinal Chemistry. PMID 31532662 DOI: 10.1021/Acs.Jmedchem.9B01247  0.056
2021 Roecker AJ, Layton ME, Pero JE, Kelly MJ, Greshock TJ, Kraus RL, Li Y, Klein R, Clements M, Daley C, Jovanovska A, Ballard JE, Wang D, Zhao F, Brunskill APJ, et al. Discovery of Arylsulfonamide Na1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity Profile. Acs Medicinal Chemistry Letters. 12: 1038-1049. PMID 34141090 DOI: 10.1021/acsmedchemlett.1c00218  0.03
2022 Klein RM, Layton ME, Regan H, Regan CP, Li Y, Filzen T, Cato M, Clements MK, Wang J, Sanoja R, Greshock TJ, Roecker AJ, Pero JE, Kim R, Burgey C, et al. Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve. Channels (Austin, Tex.). 16: 230-243. PMID 36239534 DOI: 10.1080/19336950.2022.2122309  0.02
1990 Strand WR, Chou P, Pero JE, Kaplan WE. Extrarenal Wilms tumor occurring in the inguinal canal. The Journal of Urology. 143: 783-5. PMID 2156088  0.01
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