Dong Xiao, Ph.D. - Publications

Affiliations: 
2000 University of Pennsylvania, Philadelphia, PA, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Fang F, Chen X, Zhang X, Cheng C, Xiao D, Meng Y, Ding X, Zhang H, Tian X. Environmentally friendly assembly multilayer coating for flame retardant and antimicrobial cotton fabric Progress in Organic Coatings. 90: 258-266. DOI: 10.1016/j.porgcoat.2015.09.025  0.72
2015 Zheng L, Wu X, Dong X, Ding X, Song C. Effects of Chronic Alcohol Exposure on the Modulation of Ischemia-Induced Glutamate Release via Cannabinoid Receptors in the Dorsal Hippocampus. Alcoholism, Clinical and Experimental Research. PMID 26343919 DOI: 10.1111/acer.12845  0.64
2014 Xiao D, Zhu X, Sofolarides M, Degrado S, Shao N, Rao A, Chen X, Aslanian R, Fossetta J, Tian F, Trivedi P, Lundell D, Palani A. Discovery of a novel series of potent MK2 non-ATP competitive inhibitors using 1,2-substituted azoles as cis-amide isosteres. Bioorganic & Medicinal Chemistry Letters. 24: 3609-13. PMID 24913714 DOI: 10.1016/j.bmcl.2014.05.024  1
2014 Xiao D, Zhu X, Yu Y, Shao N, Wu J, McCormick KD, Dhondi P, Qin J, Mazzola R, Tang H, Rao A, Siliphaivanh P, Qiu H, Yang X, Rivelli M, et al. Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties. Bioorganic & Medicinal Chemistry Letters. 24: 1615-20. PMID 24556380 DOI: 10.1016/j.bmcl.2014.01.043  1
2014 He S, Li P, Dai X, McComas CC, Du C, Wang P, Lai Z, Liu H, Yin J, Bulger PG, Dang Q, Xiao D, Zorn N, Peng X, Nargund RP, et al. Facile functionalization at the C2 position of a highly substituted benzofuran Tetrahedron Letters. 55: 2212-2216. DOI: 10.1016/j.tetlet.2014.02.051  1
2013 Xiao D, Palani A, Huang X, Sofolarides M, Zhou W, Chen X, Aslanian R, Guo Z, Fossetta J, Tian F, Trivedi P, Spacciapoli P, Whitehurst CE, Lundell D. Conformation constraint of anilides enabling the discovery of tricyclic lactams as potent MK2 non-ATP competitive inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3262-6. PMID 23602398 DOI: 10.1016/j.bmcl.2013.03.109  1
2013 Xiao D, Wang C, Tsui HC, Palani A, Aslanian R, Buevich AV. Conformation of gem-disubstituted alkylarylpiperidines and their implication in design and synthesis of a conformationally-rigidified NK 1 antagonist Tetrahedron Letters. 54: 6199-6203. DOI: 10.1016/j.tetlet.2013.08.131  1
2013 He S, Li P, Dai X, McComas CC, Huang H, Zhan C, Chang L, Liu Y, Chen S, Lai Z, Liu H, Yin J, Dang Q, Xiao D, Zorn N, et al. A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization Tetrahedron Letters. 54: 3755-3758. DOI: 10.1016/j.tetlet.2013.05.001  1
2012 Palani A, Rao AU, Chen X, Huang X, Su J, Tang H, Huang Y, Qin J, Xiao D, Degrado S, Sofolarides M, Zhu X, Liu Z, McKittrick B, Zhou W, et al. Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. Acs Medicinal Chemistry Letters. 3: 63-8. PMID 24900372 DOI: 10.1021/ml200243g  1
2012 Xiao D, Palani A, Sofolarides M, Aslanian R, West RE, Williams SM, Wu RL, Hwa J, Sondey C, Lachowicz J, Korfmacher WA. Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 3354-7. PMID 22464130 DOI: 10.1016/j.bmcl.2012.02.076  1
2012 Huang X, Su J, Rao AU, Tang H, Zhou W, Zhu X, Chen X, Liu Z, Huang Y, Degrado S, Xiao D, Qin J, Aslanian R, McKittrick BA, Greenfeder S, et al. SAR studies of C2 ethers of 2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-triones as nicotinic acid receptor (NAR) agonist. Bioorganic & Medicinal Chemistry Letters. 22: 854-8. PMID 22209457 DOI: 10.1016/j.bmcl.2011.12.041  1
2012 Rao AU, Xiao D, Huang X, Zhou W, Fossetta J, Lundell D, Tian F, Trivedi P, Aslanian R, Palani A. Facile synthesis of tetracyclic azepine and oxazocine derivatives and their potential as MAPKAP-K2 (MK2) inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 1068-72. PMID 22182499 DOI: 10.1016/j.bmcl.2011.11.113  1
2012 Huang X, Zhu X, Chen X, Zhou W, Xiao D, Degrado S, Aslanian R, Fossetta J, Lundell D, Tian F, Trivedi P, Palani A. A three-step protocol for lead optimization: quick identification of key conformational features and functional groups in the SAR studies of non-ATP competitive MK2 (MAPKAPK2) inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 65-70. PMID 22169260 DOI: 10.1016/j.bmcl.2011.11.074  1
2011 Qin J, Rao A, Chen X, Zhu X, Liu Z, Huang X, Degrado S, Huang Y, Xiao D, Aslanian R, Cheewatrakoolpong B, Zhang H, Greenfeder S, Farley C, Cook J, et al. Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia. Acs Medicinal Chemistry Letters. 2: 171-6. PMID 24900295 DOI: 10.1021/ml100251u  1
2011 Xiao D, Palani A, Sofolarides M, Huang Y, Aslanian R, Vaccaro H, Hong L, McKittrick B, West RE, Williams SM, Wu RL, Hwa J, Sondey C, Lachowicz J. Discovery of a series of potent arylthiadiazole H(3) antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 861-4. PMID 21186123 DOI: 10.1016/j.bmcl.2010.11.065  1
2010 Xiao D, Wang C, Palani A, Tsui HC, Reichard G, Paliwal S, Shih NY, Aslanian R, Duffy R, Lachowicz J, Varty G, Morgan C, Liu F, Nomeir A. Discovery of a series of potent, orally active α,α-disubstituted piperidine NK(1) antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 6313-5. PMID 20846861 DOI: 10.1016/j.bmcl.2010.08.059  1
2009 Xiao D, Palani A, Aslanian R, McKittrick BA, McPhail AT, Correll CC, Phelps PT, Anthes JC, Rindgen D. Spiro-piperidine azetidinones as potent TRPV1 antagonists Bioorganic and Medicinal Chemistry Letters. 19: 783-787. PMID 19114307 DOI: 10.1016/j.bmcl.2008.12.024  1
2008 Paliwal S, Reichard GA, Shah S, Wrobleski ML, Wang C, Stengone C, Tsui HC, Xiao D, Duffy RA, Lachowicz JE, Nomeir AA, Varty GB, Shih NY. Discovery of a novel, potent and orally active series of gamma-lactams as selective NK1 antagonists. Bioorganic & Medicinal Chemistry Letters. 18: 4168-71. PMID 18547807 DOI: 10.1016/j.bmcl.2008.05.082  1
2006 Shao N, Wang C, Huang X, Xiao D, Palani A, Aslanian R, Shih NY. Efficient one-pot formation of 4-N-substituted 2,4-dihydro-3H-1,2,4-triazolin-3-ones from primary amines using N′-(ethoxymethylene)hydrazinecarboxylic acid methyl ester Tetrahedron Letters. 47: 6743-6746. DOI: 10.1016/j.tetlet.2006.07.089  1
2006 Xiao D, Wang C, Palani A, Reichard G, Aslanian R, Shih NY, Buevich A. Two complementary, diversity-driven asymmetric syntheses of a 2,2-disubstituted piperidine NK1 antagonist Tetrahedron Asymmetry. 17: 2596-2598. DOI: 10.1016/j.tetasy.2006.09.022  1
2005 Xiao D, Lavey BJ, Palani A, Wang C, Aslanian RG, Kozlowski JA, Shih NY, McPhail AT, Randolph GP, Lachowicz JE, Duffy RA. Selective benzylic lithiation of N-Boc-2-phenylpiperidine and pyrrolidine: Expedient synthesis of a 2,2-disubstituted piperidine NK1 antagonist Tetrahedron Letters. 46: 7653-7656. DOI: 10.1016/j.tetlet.2005.08.148  1
2004 Huang X, Palani A, Xiao D, Aslanian R, Shih NY. Manipulation of N,O-nucleophilicity: efficient formation of 4-N-substituted 2,4-dihydro-3H-1,2,4-triazolin-3-ones. Organic Letters. 6: 4795-8. PMID 15575688 DOI: 10.1021/ol0478638  1
2001 Xiao D, Vera MD, Liang B, Joullié MM. Total synthesis of a conformationally constrained didemnin B analog. The Journal of Organic Chemistry. 66: 2734-42. PMID 11304195 DOI: 10.1021/jo001640n  1
2001 Vera MD, Pfizenmayer AJ, Ding X, Xiao D, Joullié MM. [Lys3]Didemnins as potential affinity ligands. Bioorganic & Medicinal Chemistry Letters. 11: 13-6. PMID 11140723 DOI: 10.1016/S0960-894X(00)00585-0  1
2000 Cao B, Xiao D, Joullié MM. Synthesis of Bicyclic Cyclopropylamines by Intramolecular Cyclopropanation of N-Allylamino Acid Dimethylamides. Organic Letters. 2: 1009. PMID 10814442  1
1999 Liang B, Portonovo P, Vera MD, Xiao D, Joullié MM. The first total synthesis of (-)-tamandarin A. Organic Letters. 1: 1319-22. PMID 10825982  1
1999 Pfizenmayer AJ, Ramanjulu JM, Vera MD, Ding X, Xiao D, Chen WC, Joullié MM. Synthesis and biological activities of [N-MeLeu5]- and [N-MePhe5]- didemnin B Tetrahedron. 55: 313-334.  1
1998 Pfizenmayer AJ, Vera MD, Ding X, Xiao D, Chen WC, Joullié MM. Synthesis and biological activity of [Tic5] didemnin B. Bioorganic & Medicinal Chemistry Letters. 8: 3653-6. PMID 9934489 DOI: 10.1016/S0960-894X(98)00662-3  1
1998 Xiao D, East SP, Joullié MM. Total synthesis of sanjoinine A (frangufoline) Tetrahedron Letters. 39: 9631-9632. DOI: 10.1016/S0040-4039(98)02278-3  1
1997 Xiao D, Carroll PJ, Mayer SC, Pfizenmayer AJ, Joullié MM. Stereoselective synthesis of a conformationally restricted β-hydroxy-γ-amino acid Tetrahedron Asymmetry. 8: 3043-3046. DOI: 10.1016/S0957-4166(97)00402-3  1
1996 Pfizenmayer AJ, Ramanjulu J, Vera MD, Ding X, Xiao D, Chen WC, Joullié MM. Synthesis and biological activities of [N-MeLeu5] didemnin B Bioorganic and Medicinal Chemistry Letters. 6: 2713-2716. DOI: 10.1016/S0960-894X(96)00506-9  1
1996 Xiao D, Schreier JA, Cook JH, Seybold PG, Ketcha DM. Reversible Friedel-Crafts acylations of 3-alkyl-1-(phenylsulfonyl)pyrroles: Application to the synthesis of an ant trail pheromone Tetrahedron Letters. 37: 1523-1526. DOI: 10.1016/0040-4039(96)00098-6  1
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