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John Sanders, Ph.D. - Publications

Affiliations: 
2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
biomolecular NMR
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhao Z, Harrison ST, Schubert JW, Sanders JM, Polsky-Fisher S, Zhang NR, McLoughlin D, Gibson CR, Robinson RG, Sachs NA, Kandebo M, Yao L, Smith SM, Hutson PH, Wolkenberg SE, et al. Synthesis and optimization of N-heterocyclic pyridinones as catechol-O-methyltransferase (COMT) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27133481 DOI: 10.1016/j.bmcl.2016.03.095  0.6
2016 Greshock TJ, Sanders JM, Drolet RE, Rajapakse HA, Chang RK, Kim B, Rada VL, Tiscia HE, Su H, Lai MT, Sur SM, Sanchez RI, Bilodeau MT, Renger JJ, Kern JT, et al. Potent, selective and orally bioavailable leucine-rich repeat kinase 2 (LRRK2) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27106707 DOI: 10.1016/j.bmcl.2016.04.021  0.6
2015 Raheem I, Walji A, Klein D, Sanders JM, Powell D, Abeywickrema P, Barbe G, Bennet A, Clas SD, Dubost D, Embrey M, Grobler J, Hafey M, Hartingh TJ, Hazuda DJ, et al. Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Journal of Medicinal Chemistry. PMID 26397965 DOI: 10.1021/acs.jmedchem.5b01037  0.6
2015 Harrison ST, Poslusney MS, Mulhearn JJ, Zhao Z, Kett NR, Schubert JW, Melamed JY, Allison TJ, Patel SB, Sanders JM, Sharma S, Smith RF, Hall DL, Robinson RG, Sachs NA, et al. Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT). Acs Medicinal Chemistry Letters. 6: 318-23. PMID 25815153 DOI: 10.1021/ml500502d  0.6
2015 Walji AM, Sanchez RI, Clas SD, Nofsinger R, de Lera Ruiz M, Li J, Bennet A, John C, Bennett DJ, Sanders JM, Di Marco CN, Kim SH, Balsells J, Ceglia SS, Dang Q, et al. Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption. Chemmedchem. 10: 245-52. PMID 25469982 DOI: 10.1002/cmdc.201402393  0.6
2014 Stachel SJ, Sanders JM, Henze DA, Rudd MT, Su HP, Li Y, Nanda KK, Egbertson MS, Manley PJ, Jones KL, Brnardic EJ, Green A, Grobler JA, Hanney B, Leitl M, et al. Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain. Journal of Medicinal Chemistry. 57: 5800-16. PMID 24914455 DOI: 10.1021/jm5006429  0.6
2012 Robinson RG, Smith SM, Wolkenberg SE, Kandebo M, Yao L, Gibson CR, Harrison ST, Polsky-Fisher S, Barrow JC, Manley PJ, Mulhearn JJ, Nanda KK, Schubert JW, Trotter BW, Zhao Z, ... Sanders JM, et al. Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates. Acs Chemical Neuroscience. 3: 129-40. PMID 22860182 DOI: 10.1021/cn200109w  0.6
2011 Drolet RE, Sanders JM, Kern JT. Leucine-rich repeat kinase 2 (LRRK2) cellular biology: a review of recent advances in identifying physiological substrates and cellular functions. Journal of Neurogenetics. 25: 140-51. PMID 22077787 DOI: 10.3109/01677063.2011.627072  0.6
2011 Parmentier-Batteur S, Finger EN, Krishnan R, Rajapakse HA, Sanders JM, Kandpal G, Zhu H, Moore KP, Regan CP, Sharma S, Hess JF, Williams TM, Reynolds IJ, Vacca JP, Mark RJ, et al. Attenuation of scratch-induced reactive astrogliosis by novel EphA4 kinase inhibitors. Journal of Neurochemistry. 118: 1016-31. PMID 21736568 DOI: 10.1111/j.1471-4159.2011.07375.x  0.6
2011 Wolkenberg SE, Zhao Z, Mulhearn JJ, Harrison ST, Sanders JM, Cato MJ, Jovanovska A, Panigel J, Cook SP, Henze DA, Kane SA, Hartman GD, Barrow JC. High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 2646-9. PMID 21257308 DOI: 10.1016/j.bmcl.2010.12.115  0.6
2010 Sanders JM. Optimal pi-stacking interaction energies in parallel-displaced aryl/aryl dimers are predicted by the dimer heavy atom count. The Journal of Physical Chemistry. A. 114: 9205-11. PMID 20681540 DOI: 10.1021/jp912094q  0.6
2010 Brnardic EJ, Fraley ME, Garbaccio RM, Layton ME, Sanders JM, Culberson C, Jacobson MA, Magliaro BC, Hutson PH, O'Brien JA, Huszar SL, Uslaner JM, Fillgrove KL, Tang C, Kuo Y, et al. 3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts. Bioorganic & Medicinal Chemistry Letters. 20: 3129-33. PMID 20409708 DOI: 10.1016/j.bmcl.2010.03.089  0.6
2006 Mao J, Mukherjee S, Zhang Y, Cao R, Sanders JM, Song Y, Zhang Y, Meints GA, Gao YG, Mukkamala D, Hudock MP, Oldfield E. Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. Journal of the American Chemical Society. 128: 14485-97. PMID 17090032 DOI: 10.1021/ja061737c  0.6
2006 Benaim G, Sanders JM, Garcia-Marchán Y, Colina C, Lira R, Caldera AR, Payares G, Sanoja C, Burgos JM, Leon-Rossell A, Concepcion JL, Schijman AG, Levin M, Oldfield E, Urbina JA. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. Journal of Medicinal Chemistry. 49: 892-9. PMID 16451055 DOI: 10.1021/jm050691f  0.6
2005 Sanders JM, Song Y, Chan JM, Zhang Y, Jennings S, Kosztowski T, Odeh S, Flessner R, Schwerdtfeger C, Kotsikorou E, Meints GA, Gómez AO, González-Pacanowska D, Raker AM, Wang H, et al. Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. Journal of Medicinal Chemistry. 48: 2957-63. PMID 15828834 DOI: 10.1021/jm040209d  0.6
2004 Song Y, Zhang Y, Wang H, Raker AM, Sanders JM, Broderick E, Clark A, Morita CT, Oldfield E. Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation. Bioorganic & Medicinal Chemistry Letters. 14: 4471-7. PMID 15357974 DOI: 10.1016/j.bmcl.2004.06.052  0.6
2004 Yajima S, Hara K, Sanders JM, Yin F, Ohsawa K, Wiesner J, Jomaa H, Oldfield E. Crystallographic structures of two bisphosphonate:1-deoxyxylulose-5-phosphate reductoisomerase complexes. Journal of the American Chemical Society. 126: 10824-5. PMID 15339150 DOI: 10.1021/ja040126m  0.6
2004 Sanders JM, Ghosh S, Chan JM, Meints G, Wang H, Raker AM, Song Y, Colantino A, Burzynska A, Kafarski P, Morita CT, Oldfield E. Quantitative structure-activity relationships for gammadelta T cell activation by bisphosphonates. Journal of Medicinal Chemistry. 47: 375-84. PMID 14711309 DOI: 10.1021/jm0303709  0.6
2004 Projahn HD, Steeg U, Sanders J, Vanclay E. Application of the reference-element technique for fast sequential flame atomic-absorption spectrometry Analytical and Bioanalytical Chemistry. 378: 1083-1087. DOI: 10.1007/s00216-003-2200-y  0.6
2003 Sanders JM, Gómez AO, Mao J, Meints GA, Van Brussel EM, Burzynska A, Kafarski P, González-Pacanowska D, Oldfield E. 3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates. Journal of Medicinal Chemistry. 46: 5171-83. PMID 14613320 DOI: 10.1021/jm0302344  0.6
2003 Montalvetti A, Fernandez A, Sanders JM, Ghosh S, Van Brussel E, Oldfield E, Docampo R. Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma brucei. In vitro RNA interference and in vivo inhibition studies. The Journal of Biological Chemistry. 278: 17075-83. PMID 12618430 DOI: 10.1074/jbc.M210467200  0.6
2002 Martin MB, Sanders JM, Kendrick H, de Luca-Fradley K, Lewis JC, Grimley JS, Van Brussel EM, Olsen JR, Meints GA, Burzynska A, Kafarski P, Croft SL, Oldfield E. Activity of bisphosphonates against Trypanosoma brucei rhodesiense. Journal of Medicinal Chemistry. 45: 2904-14. PMID 12086478 DOI: 10.1021/jm0102809  0.6
2002 Szabo CM, Matsumura Y, Fukura S, Martin MB, Sanders JM, Sengupta S, Cieslak JA, Loftus TC, Lea CR, Lee HJ, Koohang A, Coates RM, Sagami H, Oldfield E. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents. Journal of Medicinal Chemistry. 45: 2185-96. PMID 12014956 DOI: 10.1021/jm010412y  0.6
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