Alexander R. Dunn, Ph.D. - Publications

Stanford University, Palo Alto, CA 
 2003 California Institute of Technology, Pasadena, CA 
Dept. of Chemical Engineering

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tan SJ, Chang AC, Anderson SM, Miller CM, Prahl LS, Odde DJ, Dunn AR. Regulation and dynamics of force transmission at individual cell-matrix adhesion bonds. Science Advances. 6: eaax0317. PMID 32440534 DOI: 10.1126/Sciadv.Aax0317  0.339
2019 Terekhova K, Pokutta S, Kee YS, Li J, Tajkhorshid E, Fuller G, Dunn AR, Weis WI. Binding partner- and force-promoted changes in αE-catenin conformation probed by native cysteine labeling. Scientific Reports. 9: 15375. PMID 31653927 DOI: 10.1038/S41598-019-51816-3  0.369
2019 Bax NA, Huang DL, Pokutta S, Dunn AR, Weis WI. Force-Dependent Allosteric Enhancement of αe-Catenin Binding to F-Actin by Vinculin Biophysical Journal. 116: 549a. DOI: 10.1016/J.Bpj.2018.11.2952  0.328
2018 Price AJ, Cost AL, Ungewiß H, Waschke J, Dunn AR, Grashoff C. Mechanical loading of desmosomes depends on the magnitude and orientation of external stress. Nature Communications. 9: 5284. PMID 30538252 DOI: 10.1038/S41467-018-07523-0  0.303
2018 Tan S, Chang A, Miller C, Nath S, Dunn A. Direct Measurement of the Magnitude and Dynamics of Mechanical Forces Exerted by Single Integrins in Living Cells Biophysical Journal. 114: 653a. DOI: 10.1016/J.Bpj.2017.11.3528  0.31
2017 Huang DL, Bax NA, Buckley CD, Weis WI, Dunn AR. Vinculin forms a directionally asymmetric catch bond with F-actin. Science (New York, N.Y.). 357: 703-706. PMID 28818948 DOI: 10.1016/J.Bpj.2017.11.137  0.335
2017 Owen LM, Adhikari AS, Patel M, Grimmer P, Leijnse N, Kim MC, Notbohm J, Franck C, Dunn AR. A cytoskeletal clutch mediates cellular force transmission in a soft, 3D extracellular matrix. Molecular Biology of the Cell. PMID 28592635 DOI: 10.1091/Mbc.E17-02-0102  0.322
2017 Tan SJ, Alice CC, Mekhdjian AH, Dunn AR. Molecular Tension Sensors Reveal a Minimally Tensioned Integrin State in Living Cells Biophysical Journal. 112: 28a-29a. DOI: 10.1016/J.Bpj.2016.11.190  0.353
2016 Price AJ, Huang EY, Sebastiano V, Dunn AR. A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment. Biomaterials. 121: 179-192. PMID 28088685 DOI: 10.1016/J.Biomaterials.2016.12.005  0.306
2016 Chang AC, Mekhdjian AH, Morimatsu M, Denisin AK, Pruitt BL, Dunn AR. Single Molecule Force Measurements in Living Cells Reveal a Minimally Tensioned Integrin State. Acs Nano. PMID 27779848 DOI: 10.1021/Acsnano.6B03314  0.332
2016 Sun Z, Tseng HY, Tan S, Senger F, Kurzawa L, Dedden D, Mizuno N, Wasik AA, Thery M, Dunn AR, Fässler R. Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation. Nature Cell Biology. PMID 27548916 DOI: 10.1038/Ncb3402  0.353
2016 Tan SJ, Mekhdjian AH, Chang AC, Morimatsu M, Dunn AR. Molecular Tension Sensors for Probing the Mechanical and Chemical Roles of Distinct Integrin Classes Biophysical Journal. 110: 133a. DOI: 10.1016/J.Bpj.2015.11.764  0.346
2016 Owen LM, Adhikari AS, Patel M, Leijnse N, Cheol Kim M, Franck C, Dunn AR. Cytoskeletal and Adhesion Dynamics are Coupled to Matrix Deformation in 3D Cell Migration Biophysical Journal. 110: 623a. DOI: 10.1016/J.Bpj.2015.11.3340  0.301
2015 Chai J, Hamilton AL, Krieg M, Buckley CD, Riedel-Kruse IH, Dunn AR. A force balance can explain local and global cell movements during early zebrafish development. Biophysical Journal. 109: 407-14. PMID 26200877 DOI: 10.1016/J.Bpj.2015.04.029  0.301
2015 Sim JY, Moeller J, Hart KC, Ramallo D, Vogel V, Dunn AR, Nelson WJ, Pruitt BL. Spatial Distribution of Cell-Cell and Cell-ECM Adhesions Regulates Force Balance while Maintaining E-cadherin Molecular Tension in Cell Pairs. Molecular Biology of the Cell. PMID 25971797 DOI: 10.1091/Mbc.E14-12-1618  0.301
2015 Morimatsu M, Mekhdjian AH, Chang AC, Tan SJ, Dunn AR. Visualizing the interior architecture of focal adhesions with high-resolution traction maps. Nano Letters. 15: 2220-8. PMID 25730141 DOI: 10.1021/Nl5047335  0.302
2015 Owen LM, Adhikari AS, Kim MC, Leijnse N, Dunn AR. Actomyosin Dynamics in 3D Traction Force Generation Biophysical Journal. 108: 180a. DOI: 10.1016/J.Bpj.2014.11.995  0.326
2015 Hamilton A, Wu V, Dunn A, Riedel-Kruse I. Measuring Mechanical Force during Zebrafish Development using an Expressible Tension Sensor Biophysical Journal. 108: 494a. DOI: 10.1016/J.Bpj.2014.11.2704  0.305
2014 Buckley CD, Tan J, Anderson KL, Hanein D, Volkmann N, Weis WI, Nelson WJ, Dunn AR. Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force. Science (New York, N.Y.). 346: 1254211. PMID 25359979 DOI: 10.1126/Science.1254211  0.352
2014 Morimatsu M, Mekhdjian AH, Chang A, Dunn AR. Imaging Mechanical Force Transmission at Single Integrins in Living Cells Biophysical Journal. 106: 43a. DOI: 10.1016/J.Bpj.2013.11.313  0.372
2014 Buckley CD, Tan J, Pruitt BL, Weis WI, Nelson WJ, Dunn AR. Force-Dependent Interactions between the E-Cadherin-Catenin Complex and Actin Filaments Biophysical Journal. 106: 359a-360a. DOI: 10.1016/J.Bpj.2013.11.2042  0.342
2014 Chai J, Hamilton A, Krieg M, Buckley C, Riedel-Kruse I, Dunn A. Actomyosin Generated Tension Coordinates Cell Movements during Early Zebrafish Development Biophysical Journal. 106: 359a. DOI: 10.1016/J.Bpj.2013.11.2041  0.318
2013 Morimatsu M, Mekhdjian AH, Adhikari AS, Dunn AR. Molecular tension sensors report forces generated by single integrin molecules in living cells. Nano Letters. 13: 3985-9. PMID 23859772 DOI: 10.1021/Nl4005145  0.317
2013 Mekhdjian AH, Morimatsu M, Borghi N, Pruitt BL, Weis WI, Nelson WJ, Dunn AR. Characterization of the Biophysical Origins of Mechanical Homeostasis at Cellular Adhesions Biophysical Journal. 104: 491a. DOI: 10.1016/J.Bpj.2012.11.2708  0.338
2013 Buckley CD, Tan J, Pruitt BL, Weis WI, Nelson WJ, Dunn AR. Single-Molecule Recreation of the Cadherin/Catenin/Actin Complex Biophysical Journal. 104: 491a. DOI: 10.1016/J.Bpj.2012.11.2706  0.314
2013 Morimatsu M, Mekhdjian AH, Adhikari AS, Dunn AR. Single Piconewton Forces at Individual Integrins Support Robust Cell Adhesion Biophysical Journal. 104: 318a. DOI: 10.1016/J.Bpj.2012.11.1765  0.346
2013 Adhikari A, Leijnse N, Owen L, Oddershede L, Dunn AR. 3 Dimensional Cellular Force Microscopy in Fibrin Gels Biophysical Journal. 104: 214a. DOI: 10.1016/J.Bpj.2012.11.1211  0.312
2012 Adhikari AS, Chai J, Dunn AR. Multiplexed single-molecule force proteolysis measurements using magnetic tweezers. Journal of Visualized Experiments : Jove. PMID 22871786 DOI: 10.3791/3520  0.323
2012 Borghi N, Sorokina M, Shcherbakova OG, Weis WI, Pruitt BL, Nelson WJ, Dunn AR. E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. Proceedings of the National Academy of Sciences of the United States of America. 109: 12568-73. PMID 22802638 DOI: 10.1073/Pnas.1204390109  0.717
2012 Adhikari AS, Glassey E, Dunn AR. Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases. Journal of the American Chemical Society. 134: 13259-65. PMID 22720833 DOI: 10.1021/Ja212170B  0.314
2012 Sorokina MN, Borghi N, Shcherbakova O, Nelson J, Dunn A. Analysis of E-Cadherin as a Tension Sensor at Epithelial Cell-Cell Junctions Biophysical Journal. 102: 703a. DOI: 10.1016/J.Bpj.2011.11.3818  0.321
2011 Purcell TJ, Naber N, Franks-Skiba K, Dunn AR, Eldred CC, Berger CL, Málnási-Csizmadia A, Spudich JA, Swank DM, Pate E, Cooke R. Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency. Journal of Molecular Biology. 407: 79-91. PMID 21185304 DOI: 10.1016/J.Jmb.2010.11.053  0.328
2011 Chuan P, Spudich JA, Dunn AR. Robust mechanosensing and tension generation by myosin VI. Journal of Molecular Biology. 405: 105-12. PMID 20970430 DOI: 10.1016/J.Jmb.2010.10.010  0.317
2010 Dunn AR, Chuan P, Bryant Z, Spudich JA. Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing. Proceedings of the National Academy of Sciences of the United States of America. 107: 7746-50. PMID 20385849 DOI: 10.1016/J.Bpj.2009.12.1242  0.311
2010 Hartings MR, Kurnikov IV, Dunn AR, Winkler JR, Gray HB, Ratner MA. Electron tunneling through sensitizer wires bound to proteins. Coordination Chemistry Reviews. 254: 248-253. PMID 20161508 DOI: 10.1016/J.Ccr.2009.08.008  0.762
2009 Whited CA, Belliston-Bittner W, Dunn AR, Winkler JR, Gray HB. Nanosecond photoreduction of inducible nitric oxide synthase by a Ru-diimine electron tunneling wire bound distant from the active site. Journal of Inorganic Biochemistry. 103: 906-11. PMID 19427703 DOI: 10.1016/J.Jinorgbio.2009.04.001  0.732
2008 Whited CA, Belliston-Bittner W, Dunn AR, Winkler JR, Gray HB. Probing the heme-thiolate oxygenase domain of inducible nitric oxide synthase with Ru(II) and Re(I) electron tunneling wires. Journal of Porphyrins and Phthalocyanines. 12: 971-978. PMID 19759857 DOI: 10.1142/S1088424608000352  0.731
2008 Winkler JR, Dunn AR, Hess CR, Gray HB. Electron tunneling through iron and copper proteins Bioinorganic Electrochemistry. 1-23. DOI: 10.1007/978-1-4020-6500-2_1  0.704
2005 Belliston-Bittner W, Dunn AR, Nguyen YH, Stuehr DJ, Winkler JR, Gray HB. Picosecond photoreduction of inducible nitric oxide synthase by rhenium(I)-diimine wires. Journal of the American Chemical Society. 127: 15907-15. PMID 16277534 DOI: 10.1021/Ja0543088  0.744
2005 Contakes SM, Juda GA, Langley DB, Halpern-Manners NW, Duff AP, Dunn AR, Gray HB, Dooley DM, Guss JM, Freeman HC. Reversible inhibition of copper amine oxidase activity by channel-blocking ruthenium(II) and rhenium(I) molecular wires. Proceedings of the National Academy of Sciences of the United States of America. 102: 13451-6. PMID 16157884 DOI: 10.1073/Pnas.0506336102  0.469
2005 Dunn AR, Belliston-Bittner W, Winkler JR, Getzoff ED, Stuehr DJ, Gray HB. Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase. Journal of the American Chemical Society. 127: 5169-73. PMID 15810851 DOI: 10.1021/Ja046971M  0.646
2005 Rock RS, Ramamurthy B, Dunn AR, Beccafico S, Rami BR, Morris C, Spink BJ, Franzini-Armstrong C, Spudich JA, Sweeney HL. A flexible domain is essential for the large step size and processivity of myosin VI. Molecular Cell. 17: 603-9. PMID 15721263 DOI: 10.1016/J.Molcel.2005.01.015  0.311
2004 Hays AM, Dunn AR, Chiu R, Gray HB, Stout CD, Goodin DB. Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. Journal of Molecular Biology. 344: 455-69. PMID 15522298 DOI: 10.1016/J.Jmb.2004.09.046  0.506
2004 Rucker VC, Dunn AR, Sharma S, Dervan PB, Gray HB. Mechanism of sequence-specific fluorescent detection of DNA by N-methyl-imidazole, N-methyl-pyrrole, and β-alanine linked polyamides Journal of Physical Chemistry B. 108: 7490-7494. DOI: 10.1021/Jp037423I  0.555
2003 Dunn AR, Dmochowski IJ, Winkler JR, Gray HB. Nanosecond photoreduction of cytochrome p450cam by channel-specific Ru-diimine electron tunneling wires. Journal of the American Chemical Society. 125: 12450-6. PMID 14531688 DOI: 10.1021/Ja0294111  0.7
2003 Contakes SM, Dunn AR, Morales N, Winkler JR, Gray HB. Substrate-tethered probes for investigating the active site of myeloperoxidase Journal of Inorganic Biochemistry. 96: 120. DOI: 10.1016/S0162-0134(03)80595-0  0.603
2002 Dmochowski IJ, Dunn AR, Wilker JJ, Crane BR, Green MT, Dawson JH, Sligar SG, Winkler JR, Gray HB. Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism. Methods in Enzymology. 357: 120-33. PMID 12424904 DOI: 10.1016/S0076-6879(02)57672-2  0.745
2002 Dunn AR, Hays AM, Goodin DB, Stout CD, Chiu R, Winkler JR, Gray HB. Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening. Journal of the American Chemical Society. 124: 10254-5. PMID 12197708 DOI: 10.1021/Ja0271678  0.575
2001 Dunn AR, Dmochowski IJ, Bilwes AM, Gray HB, Crane BR. Probing the open state of cytochrome P450cam with ruthenium-linker substrates. Proceedings of the National Academy of Sciences of the United States of America. 98: 12420-5. PMID 11606730 DOI: 10.1073/Pnas.221297998  0.665
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