Carson J. Bruns, Ph.D. - Publications

2013 Chemistry Northwestern University, Evanston, IL 
Molecular Nanotechnology

170 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Sluysmans D, Hubert S, Bruns CJ, Zhu Z, Stoddart JF, Duwez AS. Synthetic oligorotaxanes exert high forces when folding under mechanical load. Nature Nanotechnology. PMID 29292379 DOI: 10.1038/s41565-017-0033-7  0.96
2017 Sluysmans D, Devaux F, Bruns CJ, Stoddart JF, Duwez AS. Dynamic force spectroscopy of synthetic oligorotaxane foldamers. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279384 DOI: 10.1073/pnas.1712790115  0.96
2017 Slack CC, Finbloom JA, Jeong K, Bruns CJ, Wemmer DE, Pines A, Francis MB. Rotaxane probes for protease detection by (129)Xe hyperCEST NMR. Chemical Communications (Cambridge, England). PMID 28044166 DOI: 10.1039/c6cc09302g  0.44
2016 Bruns CJ, Liu H, Francis MB. Near-Quantitative Aqueous Synthesis of Rotaxanes via Bioconjugation to Oligopeptides and Proteins. Journal of the American Chemical Society. 138: 15307-15310. PMID 27933926 DOI: 10.1021/jacs.6b10231  0.44
2016 Finbloom JA, Slack CC, Bruns CJ, Jeong K, Wemmer DE, Pines A, Francis MB. Rotaxane-mediated suppression and activation of cucurbit[6]uril for molecular detection by (129)Xe hyperCEST NMR. Chemical Communications (Cambridge, England). PMID 26795714 DOI: 10.1039/c5cc10410f  0.96
2016 Aytun T, Santos PJ, Bruns CJ, Huang D, Koltonow AR, Olvera De La Cruz M, Stupp SI. Self-Assembling Tripodal Small-Molecule Donors for Bulk Heterojunction Solar Cells Journal of Physical Chemistry C. 120: 3602-3611. DOI: 10.1021/acs.jpcc.5b10064  0.96
2015 Popp FC, Weigt J, Kalinski T, Betzler C, Arend J, Garlipp B, Benckert C, Bruns CJ. [Papillary tumors - therapeutic concepts]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 86: 811-22. PMID 26223666 DOI: 10.1007/s00104-015-0048-2  0.32
2015 Bruns CJ. [Complications in hepatopancreatobiliary surgery: The complexity necessitates close interdisciplinary cooperation]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 86: 517-8. PMID 26048008 DOI: 10.1007/s00104-015-0026-8  0.32
2015 Hou X, Ke C, Bruns CJ, McGonigal PR, Pettman RB, Stoddart JF. Tunable solid-state fluorescent materials for supramolecular encryption. Nature Communications. 6: 6884. PMID 25901677 DOI: 10.1038/ncomms7884  0.96
2015 Niess H, von Einem JC, Thomas MN, Michl M, Angele MK, Huss R, Günther C, Nelson PJ, Bruns CJ, Heinemann V. Treatment of advanced gastrointestinal tumors with genetically modified autologous mesenchymal stromal cells (TREAT-ME1): study protocol of a phase I/II clinical trial. Bmc Cancer. 15: 237. PMID 25879229 DOI: 10.1186/s12885-015-1241-x  0.32
2015 Schiergens TS, Reu S, Neumann J, Renz BW, Niess H, Boeck S, Heinemann V, Bruns CJ, Jauch KW, Kleespies A. Histomorphologic and molecular phenotypes predict gemcitabine response and overall survival in adenocarcinoma of the ampulla of Vater. Surgery. 158: 151-61. PMID 25819575 DOI: 10.1016/j.surg.2015.02.001  0.32
2015 Mroczkowski P, Bruns CJ. [Oncological result of T1N0M0 rectal adenocarcinoma : comparison of local and radical procedures]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 86: 289. PMID 25739710 DOI: 10.1007/s00104-015-3000-6  0.32
2015 Niess H, Camaj P, Mair R, Renner A, Zhao Y, Jäckel C, Nelson PJ, Jauch KW, Bruns CJ. Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular "pseudoinflammation" contributing to an aggressive phenotype. Oncotarget. 6: 3306-18. PMID 25650658  0.32
2015 Zhao Y, Zhao L, Ischenko I, Bao Q, Schwarz B, Nieß H, Wang Y, Renner A, Mysliwietz J, Jauch KW, Nelson PJ, Ellwart JW, Bruns CJ, Camaj P. Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer. Targeted Oncology. PMID 25639539 DOI: 10.1007/s11523-015-0360-2  0.32
2015 Bruns CJ. [Complications in liver surgery: Morbidity and mortality could be considerably reduced]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 86: 112-3. PMID 25636636 DOI: 10.1007/s00104-014-2845-4  0.32
2015 Niess H, Camaj P, Renner A, Ischenko I, Zhao Y, Krebs S, Mysliwietz J, Jäckel C, Nelson PJ, Blum H, Jauch KW, Ellwart JW, Bruns CJ. Side population cells of pancreatic cancer show characteristics of cancer stem cells responsible for resistance and metastasis. Targeted Oncology. 10: 215-27. PMID 24950733 DOI: 10.1007/s11523-014-0323-z  0.32
2015 Bruns CJ. Algorithm for diagnostics and therapy of malignant pleural mesothelioma, extracutaneous melanoma, sarcoma and pseudomyxoma peritonei | Algorithmus zur Diagnostik und Therapie bei malignem Pleuramesotheliom, extrakutanem Melanom, Sarkom und Pseudomyxoma peritonei Onkologe. 1-3. DOI: 10.1007/s00761-014-2883-z  0.32
2015 Bruns CJ, Chiapponi C, Schlag PM. Rare tumors: From “rare” to “common” | Seltene Tumoren: Vom „Seltenen“ zum „Häufigen“ Onkologe. 1-2. DOI: 10.1007/s00761-014-2882-0  0.32
2014 Angele MK, Albertsmeier M, Prix NJ, Hohenberger P, Abdel-Rahman S, Dieterle N, Schmidt M, Mansmann U, Bruns CJ, Issels RD, Jauch KW, Lindner LH. Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study. Annals of Surgery. 260: 749-54; discussion 7. PMID 25379845 DOI: 10.1097/SLA.0000000000000978  0.32
2014 Bruns CJ. [Minimally invasive oncological surgery of the upper gastrointestinal tract : state of the art]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 85: 665-7. PMID 25052814 DOI: 10.1007/s00104-014-2731-0  0.32
2014 Bruns CJ, Fujita D, Hoshino M, Sato S, Stoddart JF, Fujita M. Emergent ion-gated binding of cationic host-guest complexes within cationic M12L24 molecular flasks. Journal of the American Chemical Society. 136: 12027-34. PMID 25046565 DOI: 10.1021/ja505296e  0.96
2014 Joka M, Boeck S, Zech CJ, Seufferlein T, Wichert Gv, Licht T, Krause A, Jauch KW, Heinemann V, Bruns CJ. Combination of antiangiogenic therapy using the mTOR-inhibitor everolimus and low-dose chemotherapy for locally advanced and/or metastatic pancreatic cancer: a dose-finding study. Anti-Cancer Drugs. 25: 1095-101. PMID 25029236 DOI: 10.1097/CAD.0000000000000146  0.32
2014 Panigrahy D, Adini I, Mamluk R, Levonyak N, Bruns CJ, D'Amore PA, Klagsbrun M, Bielenberg DR. Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration. Pathology. 46: 416-23. PMID 24977735 DOI: 10.1097/PAT.0000000000000121  0.32
2014 Bruns CJ, Stoddart JF. Rotaxane-based molecular muscles. Accounts of Chemical Research. 47: 2186-99. PMID 24877992 DOI: 10.1021/ar500138u  0.96
2014 Bruns CJ. [Interdisciplinary soft tissue sarcoma surgery. New strategies in diagnostic and treatment]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 85: 376-7. PMID 24760276 DOI: 10.1007/s00104-013-2636-3  0.32
2014 Bruns CJ, Frasconi M, Iehl J, Hartlieb KJ, Schneebeli ST, Cheng C, Stupp SI, Stoddart JF. Redox switchable daisy chain rotaxanes driven by radical-radical interactions. Journal of the American Chemical Society. 136: 4714-23. PMID 24512623 DOI: 10.1021/ja500675y  0.96
2014 Bruns CJ, Li J, Frasconi M, Schneebeli ST, Iehl J, Jacquot de Rouville HP, Stupp SI, Voth GA, Stoddart JF. An electrochemically and thermally switchable donor-acceptor [c2]daisy chain rotaxane. Angewandte Chemie (International Ed. in English). 53: 1953-8. PMID 24505012 DOI: 10.1002/anie.201308498  0.96
2014 Djafarzadeh R, Conrad C, Notohamiprodjo S, Hipp S, Niess H, Bruns CJ, Nelson PJ. Cell surface engineering using glycosylphosphatidylinositol anchored tissue inhibitor of matrix metalloproteinase-1 stimulates cutaneous wound healing. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 22: 70-6. PMID 24393154 DOI: 10.1111/wrr.12132  0.32
2014 Fahrenbach AC, Bruns CJ, Li H, Trabolsi A, Coskun A, Stoddart JF. Ground-state kinetics of bistable redox-active donor-acceptor mechanically interlocked molecules. Accounts of Chemical Research. 47: 482-93. PMID 24341283 DOI: 10.1021/ar400161z  0.96
2014 Camaj P, Jäckel C, Krebs S, De Toni EN, Blum H, Jauch KW, Nelson PJ, Bruns CJ. Hypoxia-independent gene expression mediated by SOX9 promotes aggressive pancreatic tumor biology. Molecular Cancer Research : McR. 12: 421-32. PMID 24302456 DOI: 10.1158/1541-7786.MCR-13-0351  0.32
2014 Chiapponi C, Bruns CJ, Pilz F, Kanz KG, Mutschler W, Jauch KW, Siebeck M. [Structured teaching of surgery the LMU model in Munich]. Zentralblatt FüR Chirurgie. 139: 657-61. PMID 24132677 DOI: 10.1055/s-0033-1350635  0.32
2014 Zhao Y, Bao Q, Schwarz B, Zhao L, Mysliwietz J, Ellwart J, Renner A, Hirner H, Niess H, Camaj P, Angele M, Gros S, Izbicki J, Jauch KW, Nelson PJ, ... Bruns CJ, et al. Stem cell-like side populations in esophageal cancer: a source of chemotherapy resistance and metastases. Stem Cells and Development. 23: 180-92. PMID 24021093 DOI: 10.1089/scd.2013.0103  0.32
2013 Cyran CC, Schwarz B, Paprottka PM, Sourbron S, von Einem JC, Dietrich O, Hinkel R, Clevert DA, Bruns CJ, Reiser MF, Nikolaou K, Wintersperger BJ. In vivo monitoring of sorafenib therapy effects on experimental prostate carcinomas using dynamic contrast-enhanced MRI and macromolecular contrast media. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 13: 557-66. PMID 24380871 DOI: 10.1102/1470-7330.2013.0049  0.32
2013 Bruns CJ. [Surgery and teaching]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 84: 833-4. PMID 24173576 DOI: 10.1007/s00104-013-2527-7  0.32
2013 Cyran CC, Kazmierczak PM, Hirner H, Moser M, Ingrisch M, Havla L, Michels A, Eschbach R, Schwarz B, Reiser MF, Bruns CJ, Nikolaou K. Regorafenib effects on human colon carcinoma xenografts monitored by dynamic contrast-enhanced computed tomography with immunohistochemical validation. Plos One. 8: e76009. PMID 24098755 DOI: 10.1371/journal.pone.0076009  0.32
2013 Guerrero A, Loser S, Garcia-Belmonte G, Bruns CJ, Smith J, Miyauchi H, Stupp SI, Bisquert J, Marks TJ. Solution-processed small molecule:fullerene bulk-heterojunction solar cells: impedance spectroscopy deduced bulk and interfacial limits to fill-factors. Physical Chemistry Chemical Physics : Pccp. 15: 16456-62. PMID 23945610 DOI: 10.1039/c3cp52363b  0.96
2013 Jurí?ek M, Barnes JC, Dale EJ, Liu WG, Strutt NL, Bruns CJ, Vermeulen NA, Ghooray KC, Sarjeant AA, Stern CL, Botros YY, Goddard WA, Stoddart JF. Ex(2)Box: interdependent modes of binding in a two-nanometer-long synthetic receptor. Journal of the American Chemical Society. 135: 12736-46. PMID 23865381 DOI: 10.1021/ja4052763  0.96
2013 Niess H, Conrad C, Kleespies A, Haas F, Bao Q, Jauch KW, Graeb C, Bruns CJ. Surgery for metastasis to the pancreas: is it safe and effective? Journal of Surgical Oncology. 107: 859-64. PMID 23637007 DOI: 10.1002/jso.23333  0.32
2013 Zaenkert EK, Bruns CJ, Winter H, Rentsch M, Jauch KW, Hardin G, Angele MK. Resection of sarcoma involving the intrahepatic vena cava: report of 2 cases from a specialized center. Annals of Vascular Surgery. 27: 498.e9-13. PMID 23541777 DOI: 10.1016/j.avsg.2012.06.018  0.32
2013 Guba M, Angele M, Rentsch M, Jauch KW, Zachoval R, Kolligs F, Gerbes A, Bruns CJ. [Therapy of hepatocellular carcinoma before liver transplantation]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 84: 385-90. PMID 23519379 DOI: 10.1007/s00104-012-2415-6  0.32
2013 Nieß H, Kleespies A, Andrassy J, Pratschke S, Pratschke P, Angele MK, Guba M, Jauch KW, Bruns CJ. [Pancreatic cancer in the elderly: guidelines and individualized therapy]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 84: 291-5. PMID 23479275 DOI: 10.1007/s00104-012-2455-y  0.32
2013 Modest DP, Camaj P, Heinemann V, Schwarz B, Jung A, Laubender RP, Gamba S, Haertl C, Stintzing S, Primo S, Bruns CJ. KRAS allel-specific activity of sunitinib in an isogenic disease model of colorectal cancer. Journal of Cancer Research and Clinical Oncology. 139: 953-61. PMID 23455880 DOI: 10.1007/s00432-013-1401-9  0.32
2013 Nieß H, Albertsmeier M, Thomas M, Kleespies A, Angele M, Bruns CJ. [Chronic pancreatitis or pancreatic malignancy: clinical and radiological differential diagnosis of pancreas head space-occupying mass]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 84: 106-11. PMID 23400785 DOI: 10.1007/s00104-012-2374-y  0.32
2013 Haas M, Heinemann V, Kullmann F, Laubender RP, Klose C, Bruns CJ, Holdenrieder S, Modest DP, Schulz C, Boeck S. Prognostic value of CA 19-9, CEA, CRP, LDH and bilirubin levels in locally advanced and metastatic pancreatic cancer: results from a multicenter, pooled analysis of patients receiving palliative chemotherapy. Journal of Cancer Research and Clinical Oncology. 139: 681-9. PMID 23315099 DOI: 10.1007/s00432-012-1371-3  0.32
2013 Bruns CJ, Stoddart JF. Supramolecular polymers: Molecular machines muscle up. Nature Nanotechnology. 8: 9-10. PMID 23263723 DOI: 10.1038/nnano.2012.239  0.96
2013 Pratschke S, Meimarakis G, Bruns CJ, Kaspar M, Prix N, Zachoval R, Guba M, Jauch KW, Loehe F, Angele MK. Temporary intraoperative porto-caval shunt: useless or beneficial in piggy back liver transplantation? Transplant International : Official Journal of the European Society For Organ Transplantation. 26: 90-8. PMID 23237579 DOI: 10.1111/tri.12007  0.32
2013 Barnes JC, Juríček M, Strutt NL, Frasconi M, Sampath S, Giesener MA, McGrier PL, Bruns CJ, Stern CL, Sarjeant AA, Stoddart JF. ExBox: a polycyclic aromatic hydrocarbon scavenger. Journal of the American Chemical Society. 135: 183-92. PMID 22928610 DOI: 10.1021/ja307360n  0.96
2013 Ruiz-Carretero A, Aytun T, Bruns CJ, Newcomb CJ, Tsai WW, Stupp SI. Stepwise self-assembly to improve solar cell morphology Journal of Materials Chemistry A. 1: 11674-11681. DOI: 10.1039/c3ta12411h  0.96
2013 Zhu Z, Bruns CJ, Li H, Lei J, Ke C, Liu Z, Shafaie S, Colquhoun HM, Stoddart JF. Synthesis and solution-state dynamics of donor-acceptor oligorotaxane foldamers Chemical Science. 4: 1470-1483. DOI: 10.1039/c3sc00015j  0.96
2013 Bruns CJ, Herman DJ, Minuzzo JB, Lehrman JA, Stupp SI. Rationalizing molecular design in the electrodeposition of anisotropic lamellar nanostructures Chemistry of Materials. 25: 4330-4339. DOI: 10.1021/cm402505p  0.96
2013 Bruns CJ, Stoddart JF. Mechanically interlaced and interlocked donor-acceptor foldamers Advances in Polymer Science. 261: 271-294. DOI: 10.1007/12-2013-245  0.96
2013 Kleespies A, Renz B, Niess H, Pratschke S, Angele M, Bruns CJ. Advanced pancreatic cancer - Multimodality treatment | Das fortgeschrittene Pankreaskarzinom: Multimodale Therapiekonzepte Chirurgische Praxis. 77: 229-246.  0.32
2012 Jacquot de Rouville HP, Iehl J, Bruns CJ, McGrier PL, Frasconi M, Sarjeant AA, Stoddart JF. A neutral naphthalene diimide [2]rotaxane. Organic Letters. 14: 5188-91. PMID 23057862 DOI: 10.1021/ol3022963  0.96
2012 Basuray AN, Jacquot de Rouville HP, Hartlieb KJ, Kikuchi T, Strutt NL, Bruns CJ, Ambrogio MW, Avestro AJ, Schneebeli ST, Fahrenbach AC, Stoddart JF. The chameleonic nature of diazaperopyrenium recognition processes. Angewandte Chemie (International Ed. in English). 51: 11872-7. PMID 23023995 DOI: 10.1002/anie.201205089  0.96
2012 Gothard CM, Bruns CJ, Gothard NA, Grzybowski BA, Stoddart JF. Modular synthesis of bipyridinium oligomers and corresponding donor-acceptor oligorotaxanes with crown ethers. Organic Letters. 14: 5066-9. PMID 23013359 DOI: 10.1021/ol302301r  0.96
2012 Bruns CJ. [Adenocarcinoma of the esophagogastric junction: diagnostic and surgical strategies]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 83: 696-7. PMID 22878574 DOI: 10.1007/s00104-011-2260-z  0.32
2012 Fahrenbach AC, Hartlieb KJ, Sue CH, Bruns CJ, Barin G, Basu S, Olson MA, Botros YY, Bagabas A, Khdary NH, Stoddart JF. Rapid thermally assisted donor-acceptor catenation. Chemical Communications (Cambridge, England). 48: 9141-3. PMID 22854807 DOI: 10.1039/c2cc34427k  0.96
2012 Zhao L, Zhao Y, Bao Q, Niess H, Jauch KW, Bruns CJ. Clinical implication of targeting of cancer stem cells. European Surgical Research. EuropäIsche Chirurgische Forschung. Recherches Chirurgicales EuropéEnnes. 49: 8-15. PMID 22797579 DOI: 10.1159/000339610  0.32
2012 Fahrenbach AC, Bruns CJ, Cao D, Stoddart JF. Ground-state thermodynamics of bistable redox-active donor-acceptor mechanically interlocked molecules. Accounts of Chemical Research. 45: 1581-92. PMID 22741809 DOI: 10.1021/ar3000629  0.96
2012 Galata CL, Bruns CJ, Pratschke S, Tufman A, Mueller S, Winter H, Angele MK. Thoracoscopic resection of a giant midesophageal diverticulum. The Annals of Thoracic Surgery. 94: 293-5. PMID 22579888 DOI: 10.1016/j.athoracsur.2011.12.087  0.32
2012 Bao Q, Zhao Y, Niess H, Conrad C, Schwarz B, Jauch KW, Huss R, Nelson PJ, Bruns CJ. Mesenchymal stem cell-based tumor-targeted gene therapy in gastrointestinal cancer. Stem Cells and Development. 21: 2355-63. PMID 22530882 DOI: 10.1089/scd.2012.0060  0.32
2012 Klotz LV, Eichhorn ME, Schwarz B, Seeliger H, Angele MK, Jauch KW, Bruns CJ. Targeting the vasculature of visceral tumors: novel insights and treatment perspectives. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 397: 569-78. PMID 22415155 DOI: 10.1007/s00423-012-0946-4  0.32
2012 Cyran CC, Paprottka PM, Schwarz B, Sourbron S, Ingrisch M, von Einem J, Pietsch H, Dietrich O, Hinkel R, Bruns CJ, Reiser MF, Wintersperger BJ, Nikolaou K. Perfusion MRI for monitoring the effect of sorafenib on experimental prostate carcinoma: a validation study. Ajr. American Journal of Roentgenology. 198: 384-91. PMID 22268182 DOI: 10.2214/AJR.11.6951  0.32
2012 Bruns CJ, Stoddart JF. The mechanical bond: a work of art. Topics in Current Chemistry. 323: 19-72. PMID 22183145 DOI: 10.1007/128_2011_296  0.96
2012 Cyran CC, von Einem JC, Paprottka PM, Schwarz B, Ingrisch M, Dietrich O, Hinkel R, Bruns CJ, Clevert DA, Eschbach R, Reiser MF, Wintersperger BJ, Nikolaou K. Dynamic contrast-enhanced computed tomography imaging biomarkers correlated with immunohistochemistry for monitoring the effects of sorafenib on experimental prostate carcinomas. Investigative Radiology. 47: 49-57. PMID 21934514 DOI: 10.1097/RLI.0b013e3182300fe4  0.32
2012 Loser S, Bruns CJ, Miyauchi H, Ortiz RP, Facchetti A, Stupp SI, Marks TJ. Naphthodithiophene-diketopyrrolopyrrole small molecule donors for efficient solution-processed solar cells Materials Research Society Symposium Proceedings. 1390: 3-8. DOI: 10.1557/opl.2012.459  0.96
2011 Loser S, Bruns CJ, Miyauchi H, Ortiz RP, Facchetti A, Stupp SI, Marks TJ. A naphthodithiophene-diketopyrrolopyrrole donor molecule for efficient solution-processed solar cells. Journal of the American Chemical Society. 133: 8142-5. PMID 21545133 DOI: 10.1021/ja202791n  0.96
2011 Diener MK, Seiler CM, Rossion I, Kleeff J, Glanemann M, Butturini G, Tomazic A, Bruns CJ, Busch OR, Farkas S, Belyaev O, Neoptolemos JP, Halloran C, Keck T, Niedergethmann M, et al. Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial. Lancet. 377: 1514-22. PMID 21529927 DOI: 10.1016/S0140-6736(11)60237-7  0.32
2011 Pratschke S, Meimarakis G, Mayr S, Graeb C, Rentsch M, Zachoval R, Bruns CJ, Kleespies A, Jauch KW, Loehe F, Angele MK. Arterial blood flow predicts graft survival in liver transplant patients. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 17: 436-45. PMID 21445927 DOI: 10.1002/lt.22248  0.32
2011 Angele MK, Khalil PN, Spelsberg F, Bruns CJ, Burges A, Jauch KW, Kleespies A. [Non-curable tumours of the female genital tract: therapeutic options in bowel stenosis and bleeding]. Zentralblatt FüR Chirurgie. 136: 237-43. PMID 21332030 DOI: 10.1055/s-0030-1262755  0.32
2011 Haug AR, Heinemann V, Bruns CJ, Hoffmann R, Jakobs T, Bartenstein P, Hacker M. 18F-FDG PET independently predicts survival in patients with cholangiocellular carcinoma treated with 90Y microspheres. European Journal of Nuclear Medicine and Molecular Imaging. 38: 1037-45. PMID 21308371 DOI: 10.1007/s00259-011-1736-x  0.32
2011 Kleespies A, Mikhailov M, Khalil PN, Preissler G, Rentsch M, Arbogast H, Illner WD, Bruns CJ, Jauch KW, Angele MK. Enteric conversion after pancreatic transplantation: resolution of symptoms and long-term results. Clinical Transplantation. 25: 549-60. PMID 21114534 DOI: 10.1111/j.1399-0012.2010.01363.x  0.32
2011 Khalil PN, Kleespies A, Angele MK, Thasler WE, Siebeck M, Bruns CJ, Mutschler W, Kanz KG. The formal requirements of algorithms and their implications in clinical medicine and quality management. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 396: 31-40. PMID 21042918 DOI: 10.1007/s00423-010-0713-3  0.32
2011 Khalil PN, Kleespies A, Angele MK, Bruns CJ, Siebeck M. Small bowel incarceration in recurrent perineal hernia after abdominoperineal resection. International Journal of Colorectal Disease. 26: 957-8. PMID 20972798 DOI: 10.1007/s00384-010-1079-2  0.32
2011 Sargent M, Boeck S, Heinemann V, Jauch KW, Seufferlein T, Bruns CJ. Surgical treatment concepts for patients with pancreatic cancer in Germany--results from a national survey conducted among members of the "Chirurgische Arbeitsgemeinschaft Onkologie" (CAO) and the "Arbeitsgemeinschaft Internistische Onkologie" (AIO) of the Germany Cancer Society (DKG). Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 396: 223-9. PMID 20711737 DOI: 10.1007/s00423-010-0695-1  0.32
2010 Bao Q, Zhao Y, Renner A, Niess H, Seeliger H, Jauch KW, Bruns CJ. Cancer stem cells in pancreatic cancer. Cancers. 2: 1629-41. PMID 24281178 DOI: 10.3390/cancers2031629  0.32
2010 Kriegl L, Jung A, Engel J, Jackstadt R, Gerbes AL, Gallmeier E, Reiche JA, Hermeking H, Rizzani A, Bruns CJ, Kolligs FT, Kirchner T, Göke B, De Toni EN. Expression, cellular distribution, and prognostic relevance of TRAIL receptors in hepatocellular carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5529-38. PMID 20889918 DOI: 10.1158/1078-0432.CCR-09-3403  0.32
2010 Boonya-Udtayan S, Yotapan N, Woo C, Bruns CJ, Ruchirawat S, Thasana N. Synthesis and biological activities of azalamellarins. Chemistry, An Asian Journal. 5: 2113-23. PMID 20677319 DOI: 10.1002/asia.201000237  0.96
2010 Loehe F, Globke B, Marnoto R, Bruns CJ, Graeb C, Winter H, Jauch KW, Angele MK. Long-term results after surgical treatment of nonparasitic hepatic cysts. American Journal of Surgery. 200: 23-31. PMID 20637333 DOI: 10.1016/j.amjsurg.2009.06.031  0.32
2010 Khalil PN, Kleespies A, Rentsch M, Thasler WE, Jauch KW, Bruns CJ. Description and evaluation of a bench porcine model for teaching surgical residents vascular anastomosis skills. Bmc Research Notes. 3: 189. PMID 20626856 DOI: 10.1186/1756-0500-3-189  0.32
2010 Forgan RS, Friedman DC, Stern CL, Bruns CJ, Stoddart JF. Directed self-assembly of a ring-in-ring complex. Chemical Communications (Cambridge, England). 46: 5861-3. PMID 20512176 DOI: 10.1039/c0cc00776e  0.96
2010 Haas M, Laubender RP, Stieber P, Holdenrieder S, Bruns CJ, Wilkowski R, Mansmann U, Heinemann V, Boeck S. Prognostic relevance of CA 19-9, CEA, CRP, and LDH kinetics in patients treated with palliative second-line therapy for advanced pancreatic cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 31: 351-7. PMID 20480409 DOI: 10.1007/s13277-010-0044-6  0.32
2010 Staehler MD, Kruse J, Haseke N, Stadler T, Roosen A, Karl A, Stief CG, Jauch KW, Bruns CJ. Liver resection for metastatic disease prolongs survival in renal cell carcinoma: 12-year results from a retrospective comparative analysis. World Journal of Urology. 28: 543-7. PMID 20440505 DOI: 10.1007/s00345-010-0560-4  0.32
2010 Schmoldt S, Bruns CJ, Rentsch M, Siegert S, Nikolaou K, Hogardt M, Heesemann J, Tappe D. Skin fistulization associated with extensive alveolar echinococcosis. Annals of Tropical Medicine and Parasitology. 104: 175-80. PMID 20406585 DOI: 10.1179/136485910X12607012374073  0.32
2010 Seeliger H, Christians S, Angele MK, Kleespies A, Eichhorn ME, Ischenko I, Boeck S, Heinemann V, Jauch KW, Bruns CJ. Risk factors for surgical complications in distal pancreatectomy. American Journal of Surgery. 200: 311-7. PMID 20381788 DOI: 10.1016/j.amjsurg.2009.10.022  0.32
2010 Ischenko I, Seeliger H, Camaj P, Kleespies A, Guba M, Eichhorn ME, Jauch KW, Bruns CJ. Src tyrosine kinase inhibition suppresses lymphangiogenesis in vitro and in vivo. Current Cancer Drug Targets. 10: 546-53. PMID 20370688 DOI: 10.2174/156800910791517181  0.32
2010 Rentsch M, Winter H, Bruns CJ, Stintzing S, Angele MK, Jauch KW, Muacevic A. [Cyberknife surgery with a radio-scalpel: a new treatment option for patients with unresectable metastases]. Zentralblatt FüR Chirurgie. 135: 175-80. PMID 20340074 DOI: 10.1055/s-0030-1247286  0.32
2010 Rothmeier AS, Schneiders UM, Wiedmann RM, Ischenko I, Bruns CJ, Rudy A, Zahler S, Vollmar AM. The marine compound spongistatin 1 targets pancreatic tumor progression and metastasis. International Journal of Cancer. Journal International Du Cancer. 127: 1096-105. PMID 20143389 DOI: 10.1002/ijc.25241  0.32
2010 Kolligs FT, Hoffmann RT, op den Winkel M, Bruns CJ, Herrmann K, Jakobs TF, Lamerz R, Trumm C, Zech CJ, Wilkowski R, Graeb C. [Diagnosis and multimodal therapy for hepatocellular carcinoma]. Zeitschrift FüR Gastroenterologie. 48: 274-88. PMID 20119895 DOI: 10.1055/s-0028-1109901  0.32
2010 Boeck S, Haas M, Laubender RP, Kullmann F, Klose C, Bruns CJ, Wilkowski R, Stieber P, Holdenrieder S, Buchner H, Mansmann U, Heinemann V. Application of a time-varying covariate model to the analysis of CA 19-9 as serum biomarker in patients with advanced pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 986-94. PMID 20103662 DOI: 10.1158/1078-0432.CCR-09-2205  0.32
2010 Eichhorn ME, Ischenko I, Luedemann S, Strieth S, Papyan A, Werner A, Bohnenkamp H, Guenzi E, Preissler G, Michaelis U, Jauch KW, Bruns CJ, Dellian M. Vascular targeting by EndoTAG-1 enhances therapeutic efficacy of conventional chemotherapy in lung and pancreatic cancer. International Journal of Cancer. Journal International Du Cancer. 126: 1235-45. PMID 19697323 DOI: 10.1002/ijc.24846  0.32
2010 Staehler M, Haseke N, Zilinberg E, Stadler T, Karl A, Siebels M, Dürr HR, Siegert S, Jauch KW, Bruns CJ, Stief CG. Complete remission achieved with angiogenic therapy in metastatic renal cell carcinoma including surgical intervention. Urologic Oncology. 28: 139-44. PMID 19576802 DOI: 10.1016/j.urolonc.2009.03.033  0.32
2010 Ischenko I, Seeliger H, Kleespies A, Angele MK, Eichhorn ME, Jauch KW, Bruns CJ. Pancreatic cancer stem cells: new understanding of tumorigenesis, clinical implications. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 395: 1-10. PMID 19421768 DOI: 10.1007/s00423-009-0502-z  0.32
2010 Kolligs FT, Hoffmann RT, Op Den Winkel M, Bruns CJ, Herrmann K, Jakobs TF, Lamerz R, Trumm C, Zech CJ, Wilkowski R, Graeb C. Diagnosis and multimodal therapy for hepatocellular carcinoma | Diagnose und multimodale Therapie des hepatozellulären Karzinoms Tumor Diagnostik Und Therapie. 31: 152-166. DOI: 10.1055/s-0029-1245366  0.32
2010 Bruns CJ, Basu S, Fraser Stoddart J. Improved synthesis of 1,5-dinaphtho[38]crown-10 Tetrahedron Letters. 51: 983-986. DOI: 10.1016/j.tetlet.2009.12.060  0.96
2010 Kleespies A, Bruns CJ. Authors' reply: Blumgart anastomosis for pancreaticojejunostomy minimizes severe complications after pancreatic head resection British Journal of Surgery. 97: 134-135. DOI: 10.1002/bjs.6954  0.32
2009 Bruns CJ, Kleespies A, Seeliger H, Angele MK, Heinemann V, Jauch KW. [Carcinoma of head of pancreas: most common cause of obstructive jaundice]. Mmw Fortschritte Der Medizin. 151: 37, 39. PMID 20085074  0.32
2009 Wilkowski R, Boeck S, Ostermaier S, Sauer R, Herbst M, Fietkau R, Flentje M, Miethe S, Boettcher HD, Scholten T, Bruns CJ, Rau HG, Hinke A, Heinemann V. Chemoradiotherapy with concurrent gemcitabine and cisplatin with or without sequential chemotherapy with gemcitabine/cisplatin vs chemoradiotherapy with concurrent 5-fluorouracil in patients with locally advanced pancreatic cancer--a multi-centre randomised phase II study. British Journal of Cancer. 101: 1853-9. PMID 19904268 DOI: 10.1038/sj.bjc.6605420  0.32
2009 Camaj P, Seeliger H, Ischenko I, Krebs S, Blum H, De Toni EN, Faktorova D, Jauch KW, Bruns CJ. EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells. Biological Chemistry. 390: 1293-302. PMID 19804359 DOI: 10.1515/BC.2009.140  0.32
2009 Ischenko I, Seeliger H, Jauch KW, Bruns CJ. Metastatic activity and chemotherapy resistance in human pancreatic cancer--influence of cancer stem cells. Surgery. 146: 430-4. PMID 19715799 DOI: 10.1016/j.surg.2009.05.003  0.32
2009 Walz CR, Zedler S, Schneider CP, Albertsmeier M, Loehe F, Bruns CJ, Faist E, Chaudry IH, Angele MK. The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage. Innate Immunity. 15: 233-41. PMID 19586998 DOI: 10.1177/1753425909104679  0.32
2009 Boeck S, Bruns CJ, Sargent M, Schafer C, Seufferlein T, Jauch KW, Heinemann V. Current oncological treatment of patients with pancreatic cancer in germany: results from a national survey on behalf of the Arbeitsgemeinschaft Internistische Onkologie and the Chirurgische Arbeitsgemeinschaft Onkologie of the Germany Cancer Society. Oncology. 77: 40-8. PMID 19556808 DOI: 10.1159/000226110  0.32
2009 Kleespies A, Rentsch M, Seeliger H, Albertsmeier M, Jauch KW, Bruns CJ. Blumgart anastomosis for pancreaticojejunostomy minimizes severe complications after pancreatic head resection. The British Journal of Surgery. 96: 741-50. PMID 19526614 DOI: 10.1002/bjs.6634  0.32
2009 Seeliger H, Camaj P, Ischenko I, Kleespies A, De Toni EN, Thieme SE, Blum H, Assmann G, Jauch KW, Bruns CJ. EFEMP1 expression promotes in vivo tumor growth in human pancreatic adenocarcinoma. Molecular Cancer Research : McR. 7: 189-98. PMID 19208748 DOI: 10.1158/1541-7786.MCR-08-0132  0.32
2009 Conrad C, Niess H, Huss R, Huber S, von Luettichau I, Nelson PJ, Ott HC, Jauch KW, Bruns CJ. Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo. Circulation. 119: 281-9. PMID 19118255 DOI: 10.1161/CIRCULATIONAHA.108.793208  0.32
2009 Mucha SR, Rizzani A, Gerbes AL, Camaj P, Thasler WE, Bruns CJ, Eichhorst ST, Gallmeier E, Kolligs FT, Göke B, De Toni EN. JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. Gut. 58: 688-98. PMID 19106147 DOI: 10.1136/gut.2008.154625  0.32
2009 Rothmeier AS, Ischenko I, Joore J, Garczarczyk D, Fürst R, Bruns CJ, Vollmar AM, Zahler S. Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis Faseb Journal. 23: 1127-1137. PMID 19056838 DOI: 10.1096/fj.08-117127  0.32
2009 Kleespies A, Mikhailov M, Rentsch M, Preissler G, Arbogast H, Bruns CJ, Angele MK, Illner WD, Jauch KW. Cystoenteric conversion after pancreas transplantation: Indication, morbidity, and long-term results | Zysto-enterische Konversion nach Pankreastransplantation: Indikation, Morbidität und Langzeitergebnisse Transplantationsmedizin: Organ Der Deutschen Transplantationsgesellschaft. 21: 168-169.  0.32
2009 Camaj P, Ischenko I, Ziegelaar B, Faktorova D, Guba M, Jauch KW, Bruns CJ. Human primary chondrocytes exhibit an anti-angiogenic effect despite of high secretion of VEGF Gene Therapy and Molecular Biology. 13: 144-151.  0.32
2009 Bruns CJ, Hoffmann J, Jauch KW. Surgical therapy of neuroendocrine tumors of the pancreas | Chirurgische therapie von neuroendokrinen tumoren des pankreas Verdauungskrankheiten. 27: 146-151.  0.32
2008 Ischenko I, Seeliger H, Schaffer M, Jauch KW, Bruns CJ. Cancer stem cells: how can we target them? Current Medicinal Chemistry. 15: 3171-84. PMID 19075661 DOI: 10.2174/092986708786848541  0.32
2008 Ischenko I, Camaj P, Seeliger H, Kleespies A, Guba M, De Toni EN, Schwarz B, Graeb C, Eichhorn ME, Jauch KW, Bruns CJ. Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling. Oncogene. 27: 7212-22. PMID 18794807 DOI: 10.1038/onc.2008.326  0.32
2008 Kleespies A, Thasler WE, Schäfer C, Meimarakis G, Eichhorn ME, Bruns CJ, Jauch KW, Zügel N. [Acute pancreatitis: is there a need for surgery?]. Zeitschrift FüR Gastroenterologie. 46: 790-8. PMID 18759204 DOI: 10.1055/s-2008-1027467  0.32
2008 Eichhorn ME, Strieth S, Luedemann S, Kleespies A, Nöth U, Passon A, Brix G, Jauch KW, Bruns CJ, Dellian M. Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatment. Cancer Biology & Therapy. 7: 1006-13. PMID 18398295  0.32
2008 Kleespies A, Albertsmeier M, Obeidat F, Seeliger H, Jauch KW, Bruns CJ. The challenge of pancreatic anastomosis. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 393: 459-71. PMID 18379817 DOI: 10.1007/s00423-008-0324-4  0.32
2008 Brechenmacher SA, Bruns CJ, Van den Engel NK, Angele P, Loehe F, Jauch KW, Angele MK. Influence of surgical trauma on the mRNA expression of sex hormone receptors in PBMCs in male and female patients. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 393: 871-6. PMID 18297304 DOI: 10.1007/s00423-008-0304-8  0.32
2008 Manegold PC, Paringer C, Kulka U, Krimmel K, Eichhorn ME, Wilkowski R, Jauch KW, Guba M, Bruns CJ. Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 892-900. PMID 18245553 DOI: 10.1158/1078-0432.CCR-07-0955  0.32
2008 Conrad C, Zeindl-Eberhart E, Moosmann S, Nelson PJ, Bruns CJ, Huss R. Alkaline phosphatase, glutathione-S-transferase-P, and cofilin-1 distinguish multipotent mesenchymal stromal cell lines derived from the bone marrow versus peripheral blood. Stem Cells and Development. 17: 23-7. PMID 18237266 DOI: 10.1089/scd.2007.0159  0.32
2007 Boeck S, Wilkowski R, Bruns CJ, Issels RD, Schulz C, Moosmann N, Laessig D, Haas M, Golf A, Heinemann V. Oral capecitabine in gemcitabine-pretreated patients with advanced pancreatic cancer. Oncology. 73: 221-7. PMID 18424886 DOI: 10.1159/000127413  0.32
2007 Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell. 1: 313-23. PMID 18371365 DOI: 10.1016/j.stem.2007.06.002  0.32
2007 Conrad C, Niess H, Jauch KW, Bruns CJ, Hartl W, Welker L. Overture for growth hormone: requiem for interleukin-6? Critical Care Medicine. 35: 2709-13. PMID 18074473 DOI: 10.1097/01.CCM.0000291648.99043.B9  0.32
2007 Conrad C, Gupta R, Mohan H, Niess H, Bruns CJ, Kopp R, von Luettichau I, Guba M, Heeschen C, Jauch KW, Huss R, Nelson PJ. Genetically engineered stem cells for therapeutic gene delivery. Current Gene Therapy. 7: 249-60. PMID 17969558 DOI: 10.2174/156652307781369119  0.32
2007 Seeliger H, Guba M, Kleespies A, Jauch KW, Bruns CJ. Role of mTOR in solid tumor systems: a therapeutical target against primary tumor growth, metastases, and angiogenesis. Cancer Metastasis Reviews. 26: 611-21. PMID 17713840 DOI: 10.1007/s10555-007-9077-8  0.32
2007 Eichhorn ME, Luedemann S, Strieth S, Papyan A, Ruhstorfer H, Haas H, Michaelis U, Sauer B, Teifel M, Enders G, Brix G, Jauch KW, Bruns CJ, Dellian M. Cationic lipid complexed camptothecin (EndoTAG® -2) improves antitumoral efficacy by tumor vascular targeting Cancer Biology and Therapy. 6: 920-929. PMID 17534143  0.32
2007 Ischenko I, Guba M, Yezhelyev M, Papyan A, Schmid G, Green T, Fennell M, Jauch KW, Bruns CJ. Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer Angiogenesis. 10: 167-182. PMID 17486419 DOI: 10.1007/s10456-007-9071-3  0.32
2007 Eichhorn ME, Kleespies A, Angele MK, Jauch KW, Bruns CJ. Angiogenesis in cancer: Molecular mechanisms, clinical impact Langenbeck's Archives of Surgery. 392: 371-379. PMID 17458577 DOI: 10.1007/s00423-007-0150-0  0.32
2007 Conrad C, Ischenko I, Köhl G, Wiegand U, Guba M, Yezhelyev M, Ryan AJ, Barge A, Geissler EK, Wedge SR, Jauch KW, Bruns CJ. Antiangiogenic and antitumor activity of a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor ZD6474 in a metastatic human pancreatic tumor model Anti-Cancer Drugs. 18: 569-579. PMID 17414626 DOI: 10.1097/CAD.0b013e3280147d13  0.32
2007 Walz CR, Zedler S, Schneider CP, Mayr S, Loehe F, Bruns CJ, Faist E, Jauch KW, Angele MK. Depressed T cell-derived IFN-gamma following trauma-hemorrhage: a potential mechanism for diminished APC responses. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 392: 339-43. PMID 17377804 DOI: 10.1007/s00423-007-0164-7  0.32
2007 Huber S, Bruns CJ, Schmid G, Hermann PC, Conrad C, Niess H, Huss R, Graeb C, Jauch KW, Heeschen C, Guba M. Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis Kidney International. 71: 771-777. PMID 17299523 DOI: 10.1038/  0.32
2007 Schmid G, Guba M, Ischenko I, Papyan A, Joka M, Schrepfer S, Bruns CJ, Jauch KW, Heeschen C, Graeb C. The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1 Journal of Cellular Biochemistry. 101: 259-270. PMID 17203465 DOI: 10.1002/jcb.21181  0.32
2007 Loehe F, Bruns CJ, Nitsch SM, Angele MK. The role of L-arginine following trauma and blood loss Current Opinion in Clinical Nutrition and Metabolic Care. 10: 80-87. PMID 17143060 DOI: 10.1097/MCO.0b013e328011bb1b  0.32
2007 Kleespies A, Eichhorn M, Seeliger H, Jauch KW, Bruns CJ. Anastomotic complications in pancreatic surgery | Klinische anastomosenprobleme in der pankreaschirurgie Viszeralchirurgie. 42: 306-316. DOI: 10.1055/s-2007-981263  0.32
2007 Bruns CJ, Jauch KW. Surgical treatment of pancreatic cancer | Chirurgische therapie des pankreaskarzinoms Deutsche Medizinische Wochenschrift. 132: 798-802. DOI: 10.1055/s-2007-973623  0.32
2006 Wichmann MW, Roth M, Jauch KW, Bruns CJ. A prospective clinical feasibility study for multimodal "fast track" rehabilitation in elective pancreatic cancer surgery Rozhledy V Chirurgii : M¿Sí¿NíK ¿Eskoslovenské Chirurgické Spole¿Nosti.. 85: 169-175. PMID 16719412  0.32
2006 Kleespies A, Jauch KW, Bruns CJ. Tyrosine kinase inhibitors and gemcitabine: New treatment options in pancreatic cancer? Drug Resistance Updates. 9: 1-18. PMID 16621676 DOI: 10.1016/j.drup.2006.02.002  0.32
2005 Hartmann B, Schmid G, Graeb C, Bruns CJ, Fischereder M, Jauch KW, Heeschen C, Guba M. Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: A novel approach for tailored immunosuppressive therapy Kidney International. 68: 2593-2598. PMID 16316335 DOI: 10.1111/j.1523-1755.2005.00731.x  0.32
2005 Kleespies A, Bruns CJ, Jauch KW. Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies Onkologie. 28: 281-288. PMID 15867486 DOI: 10.1159/000085198  0.32
2005 Schmid G, Guba M, Papyan A, Ischenko I, Brückel M, Bruns CJ, Jauch KW, Graeb C. FTY720 inhibits tumor growth and angiogenesis Transplantation Proceedings. 37: 110-111. PMID 15808563 DOI: 10.1016/j.transproceed.2004.12.278  0.32
2005 Guba M, Yezhelyev M, Eichhorn ME, Schmid G, Ischenko I, Papyan A, Graeb C, Seeliger H, Geissler EK, Jauch KW, Bruns CJ. Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF Blood. 105: 4463-4469. PMID 15671443 DOI: 10.1182/blood-2004-09-3540  0.32
2005 Bruell D, Bruns CJ, Yezhelyev M, Huhn M, Müller J, Ischenko I, Fischer R, Finnern R, Jauch KW, Barth S. Recombinant anti-EGFR immunotoxin 425(scFv)-ETA' demonstrates anti-tumor activity against disseminated human pancreatic cancer in nude mice International Journal of Molecular Medicine. 15: 305-313. PMID 15647848  0.32
2005 Bangard C, Gossmann A, Papyan A, Tawadros S, Hellmich M, Bruns CJ. Magnetic resonance imaging in an orthotopic rat model: Blockade of epidermal growth factor receptor with EMD72000 inhibits human pancreatic carcinoma growth International Journal of Cancer. 114: 131-138. PMID 15523683 DOI: 10.1002/ijc.20696  0.32
2005 Kleespies A, Köhl G, Friedrich M, Ryan AJ, Barge A, Jauch KW, Bruns CJ. Vascular targeting in pancreatic cancer: The novel tubulin-binding agent ZD6126 reveals antitumor activity in primary and metastatic tumor models Neoplasia. 7: 957-966. DOI: 10.1593/neo.05304  0.32
2004 Yezhelyev MV, Koehl G, Guba M, Brabletz T, Jauch KW, Ryan A, Barge A, Green T, Fennell M, Bruns CJ. Inhibition of Src tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice Clinical Cancer Research. 10: 8028-8036. PMID 15585638 DOI: 10.1158/1078-0432.CCR-04-0621  0.32
2004 Brabletz T, Spaderna S, Kolb J, Hlubek F, Faller G, Bruns CJ, Jung A, Nentwich J, Duluc I, Domon-Dell C, Kirchner T, Freund JN. Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: An active role for the tumor environment in malignant tumor progression Cancer Research. 64: 6973-6977. PMID 15466189 DOI: 10.1158/0008-5472.CAN-04-1132  0.32
2004 Kleespies A, Guba M, Jauch KW, Bruns CJ. Vascular endothelial growth factor in esophageal cancer Journal of Surgical Oncology. 87: 95-104. PMID 15282704 DOI: 10.1002/jso.20070  0.32
2004 Bruns CJ, Koehl GE, Guba M, Yezhelyev M, Steinbauer M, Seeliger H, Schwend A, Hoehn A, Jauch KW, Geissler EK. Rapamycin-Induced Endothelial Cell Death and Tumor Vessel Thrombosis Potentiate Cytotoxic Therapy against Pancreatic Cancer Clinical Cancer Research. 10: 2109-2119. PMID 15041732 DOI: 10.1158/1078-0432.CCR-03-0502  0.32
2004 Seeliger H, Guba M, Koehl GE, Doenecke A, Steinbauer M, Bruns CJ, Wagner C, Frank E, Jauch KW, Geissler EK. Blockage of 2-Deoxy-D-Ribose-Induced Angiogenesis with Rapamycin Counteracts a Thymidine Phosphorylase-Based Escape Mechanism Available for Colon Cancer under 5-Fluorouracil Therapy Clinical Cancer Research. 10: 1843-1852. PMID 15014039 DOI: 10.1158/1078-0432.CCR-1176-3  0.32
2004 Swol-Ben J, Bruns CJ, Müller-Ladner U, Hofstädter F, Link J, Hechenrieder C, Jauch KW. Leukoencephalopathy and chronic pancreatitis as concomitant manifestations of systemic lupus erythematosus related to anticardiolipin antibodies Rheumatology International. 24: 177-181. PMID 12937945 DOI: 10.1007/s00296-003-0366-4  0.32
2003 Bruell D, Stöcker M, Huhn M, Redding N, Küpper M, Schumacher P, Paetz A, Bruns CJ, Haisma HJ, Fischer R, Finnern R, Barth S. The recombinant anti-EGF receptor immunotoxin 425(scFv)-ETA' suppresses growth of a highly metastatic pancreatic carcinoma cell line. International Journal of Oncology. 23: 1179-86. PMID 12964002  0.32
2003 Parikh AA, Biao Liu W, Fan F, Stoeltzing O, Reinmuth N, Bruns CJ, Bucana CD, Evans DB, Ellis LM. Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma Cancer. 98: 720-729. PMID 12910515 DOI: 10.1002/cncr.11560  0.32
2003 Wilkowski R, Heinemann V, Wagner A, Bruns CJ, Schauer R, Thoma M. Will new agents promise a better prognosis? - Interdisciplinary therapy of pancratic cancer | Können neue substanzen endlich die prognose verbessern? Interdisziplinäre behandlung des pankreaskarzinoms Klinikarzt. 32: 242-247. DOI: 10.1055/s-2003-40959  0.32
2003 Bruns CJ. Anti-angiogenetic therapy strategies against pancreatic cancer | Antiangiogenetische therapieansätze beim pankreaskarzinom Viszeralchirurgie. 38: 205-210. DOI: 10.1055/s-2003-40017  0.32
2002 Nawrocki ST, Bruns CJ, Harbison MT, Bold RJ, Gotsch BS, Abbruzzese JL, Elliott P, Adams J, McConkey DJ. Effects of the proteasome inhibitor ps-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts Molecular Cancer Therapeutics. 1: 1243-1253. PMID 12516957  0.32
2002 Bruns CJ, Shrader M, Harbison MT, Portera C, Solorzano CC, Jauch KW, Hicklin DJ, Radinsky R, Ellis LM. Effect of the vascular endothelial growth factor receptor-2 antibody DC101 plus gemcitabine on growth, metastasis and angiogenesis of human pancreatic cancer growing orthotopically in nude mice. International Journal of Cancer. Journal International Du Cancer. 102: 101-8. PMID 12385004 DOI: 10.1002/ijc.10681  0.32
2002 Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, Bruns CJ, Zuelke C, Farkas S, Anthuber M, Jauch KW, Geissler EK. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nature Medicine. 8: 128-35. PMID 11821896 DOI: 10.1038/nm0202-128  0.32
2001 Solorzano CC, Baker CH, Bruns CJ, Killion JJ, Ellis LM, Wood J, Fidler IJ. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biotherapy & Radiopharmaceuticals. 16: 359-70. PMID 11776753 DOI: 10.1089/108497801753354267  0.32
2001 Ozawa S, Shinohara H, Kanayama HO, Bruns CJ, Bucana CD, Ellis LM, Davis DW, Fidler IJ. Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha. Neoplasia (New York, N.Y.). 3: 154-64. PMID 11420751 DOI: 10.1038/sj/neo/7900128  0.32
2001 Papyan A, Stolz U, Dries V, Schneider PM, Hölscher AH, Grell M, Joncyzk A, Bruns CJ. Regression of human pancreatic cancer metastasis by avb3/b5 Langenbeck's Archives of Surgery. 386: 470.  0.32
2001 Bruns CJ, Ozawa S, Harbison MT, Tsan V, Solorzano CC, McConkey DJ, Radinsky R, Kölscher AH, Fidler IJ. Inhibition of Angiogenesis and regression of human pancreatic cancer by blockade of egf-r signal transduction in combination with gemcitabine Langenbeck's Archives of Surgery. 386: 386.  0.32
2001 Bruns CJ, Gossmann A, Papyan A, Bangard C, Schneider PM, Kreysch HG, Lackner K, Hölscher AM. Contrast enhanced MRI as in vivo monitoring for the anti-angiogenic effect of EGF-R blockade in pancreatic cancer growing orthotopically in nude rats Langenbeck's Archives of Surgery. 386: 385.  0.32
2000 Inoue K, Slaton JW, Perrotte P, Davis DW, Bruns CJ, Hicklin DJ, McConkey DJ, Sweeney P, Radinsky R, Dinney CP. Paclitaxel enhances the effects of the anti-epidermal growth factor receptor monoclonal antibody ImClone C225 in mice with metastatic human bladder transitional cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 4874-84. PMID 11156247  0.32
2000 Bruns CJ, Liu W, Davis DW, Shaheen RM, McConkey DJ, Wilson MR, Bucana CD, Hicklin DJ, Ellis LM. Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases. Cancer. 89: 488-99. PMID 10931447 DOI: 10.1002/1097-0142(20000801)89:3<488::AID-CNCR3>3.0.CO;2-X  0.32
2000 Jean D, Tellez C, Huang S, Davis DW, Bruns CJ, McConkey DJ, Hinrichs SH, Bar-Eli M. Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment. Oncogene. 19: 2721-30. PMID 10851072 DOI: 10.1038/sj.onc.1203569  0.32
2000 Bruns CJ, Solorzano CC, Harbison MT, Ozawa S, Tsan R, Fan D, Abbruzzese J, Traxler P, Buchdunger E, Radinsky R, Fidler IJ. Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Research. 60: 2926-35. PMID 10850439  0.32
2000 Bruns CJ, Harbison MT, Davis DW, Portera CA, Tsan R, McConkey DJ, Evans DB, Abbruzzese JL, Hicklin DJ, Radinsky R. Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 1936-48. PMID 10815919  0.32
2000 Bruns CJ, Shinohara H, Harbison MT, Davis DW, Nelkin G, Killion JJ, McConkey DJ, Dong Z, Fidler IJ. Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages. Cancer Research. 60: 2-7. PMID 10646841  0.32
1999 Bruns CJ, Harbison MT, Kuniyasu H, Eue I, Fidler IJ. In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice Neoplasia (New York, N.Y.). 1: 50-62. PMID 10935470  0.32
1998 Bruns CJ, Neuhof D, Erasmi H, Schmitz-Rixen T. In vivo biomechanical properties of three different graft materials in peripheral vascular surgery International Journal of Angiology. 7: 52-56. DOI: 10.1007/s005479900062  0.32
1997 Bruns CJ, Gawenda M, Wolfgarten B, Walter M. Anastomotic stricture after esophagectomy and gastric tube reconstruction for esophageal cancer retrospective analysis from 1989 to 1995 | Collare anastomosenstenosen nach magenhochzug beim osophaguskarzinomauswertung des eigenen patientenguts von 1989- 1995 Langenbecks Archiv Fur Chirurgie. 382: 145-148. PMID 9324613 DOI: 10.1007/s004230050044  0.32
1996 Bruns CJ, Schäfer H, Wolfgarten B, Engert A. Effect of intraoperative blood loss on the function of natural killer cells in tumors of the upper gastrointestinal tract | Einfluss des intraoperativen Blutverlustes auf die Funktion der natürlichen Killerzellen bei Tumoren des oberen Gastrointestinaltraktes Langenbecks Archiv FüR Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft FüR Chirurgie. Kongress. 113: 146-149. PMID 9101816  0.32
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