Adam T. Hoye, Ph.D. - Related publications

Affiliations: 
2010 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Chemical Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Sun Z, Yang S, Xu C, Yi F, Cao L, Tian Y, Lin J, Xu X. Concise total synthesis of (+)-Zeylenone with antitumor activity and the structure-activity relationship of its derivatives. Bioorganic Chemistry. 116: 105333. PMID 34537516 DOI: 10.1016/j.bioorg.2021.105333   
2021 Zhou N, Zhao J, Sun C, Lai Y, Ruan Z, Feng P. Electro-Oxidative C-N Bond Formation through Azolation of Indole Derivatives: An Access to 3-Substituent-2-(Azol-1-yl)indoles. The Journal of Organic Chemistry. PMID 34520191 DOI: 10.1021/acs.joc.1c01271   
2021 Kagho MD, Hintersatz H, Ihle A, Zeng H, Schrey H, Colisi W, Klahn P, Stadler M, Bruhn C, Rüffer T, Lang H, Banert K. Total Synthesis via Biomimetic Late-Stage Heterocyclization: Assignment of the Relative Configuration and Biological Evaluation of the Nitraria Alkaloid (±)-Nitrabirine. The Journal of Organic Chemistry. PMID 34570972 DOI: 10.1021/acs.joc.1c01650   
2021 Ramos-Orea A, Ramírez-Apan T, Chávez-Santos RM, Aguayo-Ortiz R, Espitia C, Silva Miranda M, Torres-Ochoa RO, Martínez R. Total syntheses and antiproliferative activities of prenostodione and its analogues. Organic & Biomolecular Chemistry. 19: 8272-8280. PMID 34518856 DOI: 10.1039/d1ob00897h   
2021 Sun CP, Yi J, Wei F, Lv X, Deng S, Zhang BJ, Zhao WY, Ma XC. UV-light-driven photooxidation of harmaline catalyzed by riboflavin: Product characterization and mechanisms. Fitoterapia. 105054. PMID 34626737 DOI: 10.1016/j.fitote.2021.105054   
2021 Klumthong K, Chalermsub P, Sopha P, Ruchirawat S, Ploypradith P. An Expeditious Modular Hybrid Strategy for the Diversity-Oriented Synthesis of Lamellarins/Azalamellarins with Anticancer Cytotoxicity. The Journal of Organic Chemistry. PMID 34436897 DOI: 10.1021/acs.joc.1c01639   
2021 Hu M, Wu Z, Yao B, Li J, Wu W, Jiang H. Pd-Catalyzed Sequential Formation of C-C Bonds: A New Strategy for the Synthesis of ()-α,β-Unsaturated Carbonyl Compounds from Sulfoxonium Ylides and 1-Iodo-2-((2-methylallyl)oxy)benzene Compounds. The Journal of Organic Chemistry. 86: 11545-11556. PMID 34479410 DOI: 10.1021/acs.joc.1c01119   
2021 Tawiah A, Pipim GB, Tia R, Adei E. Exploring the chemo-, regio-, and stereoselectivities of the (3 + 2) cycloaddition reaction of 5,5-dimethyl-3-methylene-2-pyrrolidinone with C,N-diarylnitrones and nitrile oxide derivatives: a DFT study. Journal of Molecular Modeling. 27: 287. PMID 34532750 DOI: 10.1007/s00894-021-04911-0   
2021 Jeon YK, Kim WS. 1,3-Aza-Brook Rearrangement of Aniline Derivatives: In Situ Generation of 3-Aminoaryne via 1,3-C-(sp)-to-N Silyl Migration. Organic Letters. PMID 34553933 DOI: 10.1021/acs.orglett.1c02751   
2021 Vuong W, Vederas JC. Improved Synthesis of a Cyclic Glutamine Analogue Used in Antiviral Agents Targeting 3C and 3CL Proteases Including SARS-CoV-2 M. The Journal of Organic Chemistry. PMID 34459196 DOI: 10.1021/acs.joc.1c01299   
2021 Dai M, Wang YC, Cui C. Flow Chemistry-Enabled Divergent and Enantioselective Total Syntheses of Massarinolin A, Purpurolides B, D, E, 2,3-Deoxypurpurolide C, and Structural Revision of Massarinolin A. Angewandte Chemie (International Ed. in English). PMID 34405497 DOI: 10.1002/anie.202109625   
2021 Ganaie BA, Shahid M, Rashid A, Ara T, Ahmad Banday J, Malik F, Bhat BA. Platanic Acid-Aryl Enones as Potential Anticancer Compounds: Synthesis and Biological Profiling against Breast, Prostate and Lung Cancer Cell Lines. Chemistry & Biodiversity. e2100292. PMID 34467653 DOI: 10.1002/cbdv.202100292   
2021 Thirupataiah B, Reddy GS, Mounika G, Kumar JS, Hossain KA, Mudgal J, Mathew JE, Shenoy GG, Rajadurai M, Parsa KVL, Pal M. Pd-catalysed general access to 7-membered N/O-heterocyclic compounds as potential agents against inflammation. Chemical Communications (Cambridge, England). PMID 34515287 DOI: 10.1039/d1cc04140a   
2021 Kang QQ, Zhang WK, Ge GP, Zheng H, Wei WT. The construction of benzimidazo[2,1-]isoquinolin-6(5)-ones from -methacryloyl-2-phenylbenzoimidazoles through radical strategies. Organic & Biomolecular Chemistry. PMID 34610071 DOI: 10.1039/d1ob01465j   
2021 Saroha B, Kumar G, Kumar R, Kumari M, Kumar S. A minireview of 1,2,3-Triazole hybrids with O-Heterocycles as leads in medicinal chemistry. Chemical Biology & Drug Design. PMID 34592059 DOI: 10.1111/cbdd.13966   
2021 Neal MJ, Hejnosz SL, Rohde JJ, Evanseck JD, Montgomery TD. Multi-Ion Bridged Pathway of -Oxides to 1,3-Dipole Dilithium Oxide Complexes. The Journal of Organic Chemistry. PMID 34379424 DOI: 10.1021/acs.joc.1c01047   
2021 Halder A, Mahanty K, Maiti D, De Sarkar S. Highly Diastereoselective Synthesis of Dihydro-benzoimidazo-[1,3]-thiazines via Electro-oxidative Selenocyclization of Thioallyl Benzoimidazoles. Chemistry, An Asian Journal. PMID 34609085 DOI: 10.1002/asia.202101033   
2021 Miao SX, Wan LX, He ZX, Zhou XL, Li X, Gao F. Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of -Aryl Huperzine A Analogues. Journal of Natural Products. 84: 2374-2379. PMID 34445873 DOI: 10.1021/acs.jnatprod.1c00600   
2021 Xu Y, Xie J, Wu WC, Chen BT, Zhang SQ, Wang R, Huang J, Guo ZK. Discovery of an unprecedented benz[α]anthraquinone-type heterodimer from a rare actinomycete Amycolatopsis sp. HCa1. Fitoterapia. 105039. PMID 34592372 DOI: 10.1016/j.fitote.2021.105039   
2021 Chao M, Wang F, Xu L, Ju Y, Chen Z, Wang B, Gong P, You J, Jin M, Shen D. Cerium Ammonium Nitrate-Mediated Access to Biaryl Lactones: Substrate Scopes and Mechanism Studies. The Journal of Organic Chemistry. PMID 34533324 DOI: 10.1021/acs.joc.1c01479   
2021 Pluskota R, Jaroch K, Kośliński P, Ziomkowska B, Lewińska A, Kruszewski S, Bojko B, Koba M. Selected Drug-Likeness Properties of 2-Arylidene-indan-1,3-dione Derivatives-Chemical Compounds with Potential Anti-Cancer Activity. Molecules (Basel, Switzerland). 26. PMID 34500689 DOI: 10.3390/molecules26175256   
2021 Yuan X, Yu X, He K, Zhang R, Xiao W, Lin J, Zhan Z, Cheng X, Shao Z, Jin Y. Dual C(sp)-H Functionalization of Cyclic Ethers via Singlet Oxygen-Mediated Ring Opening and Ring Closing. Organic Letters. PMID 34633191 DOI: 10.1021/acs.orglett.1c03008   
2021 Venkatakrishnan P, Maddala S, Panua A. Steering Scholl Oxidative Heterocoupling by Tuning Topology and Electronics for Building Thiananographenes and Their Functional N-/C-Congeners. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34459037 DOI: 10.1002/chem.202102920   
2021 Kunwar S, Hwang SY, Katila P, Seo M, Man Kadayat T, Kwon Y, Lee ES. 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships. Bioorganic Chemistry. 116: 105349. PMID 34536927 DOI: 10.1016/j.bioorg.2021.105349   
2021 Tombari RJ, Tuck JR, Yardeny N, Gingrich PW, Tantillo DJ, Olson DE. Calculated oxidation potentials predict reactivity in Baeyer-Mills reactions. Organic & Biomolecular Chemistry. 19: 7575-7580. PMID 34524347 DOI: 10.1039/d1ob01450a   
2021 Munikishore R, Wang LL, Zhang S, Zhao QS, Zuo Z. An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94. Bioorganic Chemistry. 116: 105317. PMID 34488126 DOI: 10.1016/j.bioorg.2021.105317   
2021 Kirschner S, Yuan K, Ingleson MJ. Haloboration: scope, mechanism and utility. New Journal of Chemistry = Nouveau Journal De Chimie. 45: 14855-14868. PMID 34483652 DOI: 10.1039/d0nj02908d   
2021 Shi Y, Fu L, Yang J, Carroll KS. Wittig reagents for chemoselective sulfenic acid ligation enables global site stoichiometry analysis and redox-controlled mitochondrial targeting. Nature Chemistry. PMID 34531572 DOI: 10.1038/s41557-021-00767-2   
2021 Yin C, Zhong T, Zheng X, Li L, Zhou J, Yu C. Direct synthesis of indazole derivatives Rh(III)-catalyzed C-H activation of phthalazinones and allenes. Organic & Biomolecular Chemistry. 19: 7701-7705. PMID 34524333 DOI: 10.1039/d1ob01458g   
2021 Kinouchi H, Sugimoto K, Yamaoka Y, Takikawa H, Takasu K. Oxidative β-Cleavage of Fused Cyclobutanols Leading to Hydrofuran-Fused Polycyclic Aromatic Compounds. The Journal of Organic Chemistry. 86: 12615-12622. PMID 34474562 DOI: 10.1021/acs.joc.1c01108   
2021 Ferla S, Varricchio C, Knight W, Ho PK, Saporito F, Tropea B, Fagan G, Flude BM, Bevilacqua F, Santos-Ferreira N, Van Dycke J, Neyts J, Brancale A, Rocha-Pereira J, Bassetto M. Structure-Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections. Microorganisms. 9. PMID 34576691 DOI: 10.3390/microorganisms9091795   
2021 Lautens M, Loup J, Larin EM. Iron-Catalyzed Reductive Cyclization by Hydromagnesiation: A Modular Strategy Towards N-Heterocycles. Angewandte Chemie (International Ed. in English). PMID 34409717 DOI: 10.1002/anie.202106996   
2021 Kazakova O, Rubanik L, Lobov A, Poleshchuk N, Baikova I, Kapustina Y, Petrova A, Korzun T, Lopatina T, Fedorova A, Rybalova T, Polovianenko D, Mioc M, Șoica C. Synthesis of erythrodiol C-ring derivatives and their activity against Chlamydia trachomatis. Steroids. 175: 108912. PMID 34480919 DOI: 10.1016/j.steroids.2021.108912   
2021 Apostol TV, Marutescu LG, Draghici C, Socea LI, Olaru OT, Nitulescu GM, Pahontu EM, Saramet G, Enache-Preoteasa C, Barbuceanu SF. Synthesis and Biological Evaluation of New -Acyl-α-amino Ketones and 1,3-Oxazoles Derivatives. Molecules (Basel, Switzerland). 26. PMID 34443608 DOI: 10.3390/molecules26165019   
2021 Jiang D, Wang S. Oxidative Cyclization of Kynuramine and Ynones Enabling Collective Syntheses of Pyridoacridine Alkaloids. The Journal of Organic Chemistry. PMID 34648288 DOI: 10.1021/acs.joc.1c02009   
2021 Jiang Y, Liu L, Shi Z, Zhang X, Zhan F, Lin JS. Synthesis of α-Amino Tertiary Alkylperoxides by Lewis Acid Catalyzed Peroxidation of 1,3,5-Triazines. Chemistry, An Asian Journal. PMID 34478220 DOI: 10.1002/asia.202100833   
2021 Fu L, Dai DC, Yang R, Chen GY, Zheng CJ, Song XM, Zhou XM. Two novel aporphine-derived alkaloids from the stems of Fissistigma glaucescens. Fitoterapia. 105036. PMID 34536535 DOI: 10.1016/j.fitote.2021.105036   
2021 Wu Y, Wen K, Chen J, Shi J, Yao X, Tang X. Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds. Organic Letters. PMID 34612042 DOI: 10.1021/acs.orglett.1c02897   
2021 Thirupataiah B, Mounika G, Sujeevan Reddy G, Sandeep Kumar J, Kapavarapu R, Medishetti R, Mudgal J, Mathew JE, Shenoy GG, Mallikarjuna Rao C, Chatti K, V L Parsa K, Pal M. CuCl-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling-cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors. Bioorganic Chemistry. 115: 105265. PMID 34426160 DOI: 10.1016/j.bioorg.2021.105265   
2021 Tahir T, Ashfaq M, Saleem M, Rafiq M, Shahzad MI, Kotwica-Mojzych K, Mojzych M. Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives. Molecules (Basel, Switzerland). 26. PMID 34443460 DOI: 10.3390/molecules26164872   
2021 Blum S, Nickel C, Schäffer L, Karakaya T, Waldvogel SR. Electrochemical Nitration with Nitrite. Chemsuschem. PMID 34583423 DOI: 10.1002/cssc.202102053   
2021 Wang T, Li L, Zhou Y, Lu A, Li H, Chen J, Duan Z, Wang Q. Structural Simplification of Marine Natural Products: Discovery of Hamacanthin Derivatives Containing Indole and Piperazinone as Novel Antiviral and Anti-phytopathogenic-fungus Agents. Journal of Agricultural and Food Chemistry. PMID 34450009 DOI: 10.1021/acs.jafc.1c04098   
2021 Wang Z, Yue G, Ji X, Song H, Yan P, Zhao J, Jia X. Tandem Michael Addition-Cyclization of Nitroalkenes with 1,3-Dicarbonyl Compounds Accompanied by Removal of Nitro Group. The Journal of Organic Chemistry. PMID 34494850 DOI: 10.1021/acs.joc.1c01586   
2021 Tanaka K, Kobayashi K, Kogen H. Enantioselective total synthesis of (+)-rubrobramide, (+)-talaramide A, and (-)-berkeleyamide D by a skeletal diversification strategy. Chemical Communications (Cambridge, England). PMID 34486624 DOI: 10.1039/d1cc04290d   
2021 Wang X, Hu N, Kong W, Song B, Li S. Facile and divergent optimization of chromazonarol enabled the identification of simplified drimane meroterpenoids as novel pharmaceutical leads. European Journal of Medicinal Chemistry. 227: 113912. PMID 34653771 DOI: 10.1016/j.ejmech.2021.113912   
2021 Talha A, Favreau C, Bourgoin M, Robert G, Auberger P, El Ammari L, Saadi M, Benhida R, Martin AR, Bougrin K. Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies. Ultrasonics Sonochemistry. 78: 105748. PMID 34520963 DOI: 10.1016/j.ultsonch.2021.105748   
2021 Trestsova MA, Utepova IA, Chupakhin ON, Semenov MV, Pevtsov DN, Nikolenko LM, Tovstun SA, Gadomska AV, Shchepochkin AV, Kim GA, Razumov VF, Dorosheva IB, Rempel AA. Oxidative C-H/C-H Coupling of Dipyrromethanes with Azines by TiO-Based Photocatalytic System. Synthesis of New BODIPY Dyes and Their Photophysical and Electrochemical Properties. Molecules (Basel, Switzerland). 26. PMID 34577020 DOI: 10.3390/molecules26185549   
2021 Shelke YG, Hande PE, Gharpure SJ. Recent advances in the synthesis of pyrrolo[1,2-]indoles and their derivatives. Organic & Biomolecular Chemistry. 19: 7544-7574. PMID 34524330 DOI: 10.1039/d1ob01103k   
2021 Hou BL, Wong JJ, Lv N, Wang YQ, Houk KN, Li CC. Facile generation of bridged medium-sized polycyclic systems by rhodium-catalysed intramolecular (3+2) dipolar cycloadditions. Nature Communications. 12: 5239. PMID 34475378 DOI: 10.1038/s41467-021-25513-7   
2021 Ren J, Du FH, Jia MC, Hu ZN, Chen Z, Zhang C. Ring Expansion Fluorination of Unactivated Cyclopropanes Mediated by a New Monofluoroiodane(III) Reagent. Angewandte Chemie (International Ed. in English). PMID 34523779 DOI: 10.1002/anie.202108589