| Year |
Citation |
Score |
| 2023 |
Wachira FW, Githirwa DC, McPartlon T, Nazarenko V, Gonzales JJC, Gazura MM, Leen C, Clary HR, Alston C, Klees LM, Yao L, An M. D-to-E and T19V Variants of the pH-Low Insertion Peptide and Their Doxorubicin Conjugates Interact with Membrane at Higher pH Ranges Than WT. Biochemistry. 62: 2997-3011. PMID 37793002 DOI: 10.1021/acs.biochem.3c00218 |
0.83 |
|
| 2019 |
Otieno SA, Klees LM, Zhang A, Giza HM, Hanz SZ, Chakravorty B, Yao L, An M, Qiang W. The pH-Specific Thermodynamic Intermediates of Phlip Membrane Insertion Biophysical Journal. 116: 513a. DOI: 10.1016/J.Bpj.2018.11.2766 |
0.802 |
|
| 2018 |
Otieno SA, Hanz SZ, Chakravorty B, Zhang A, Klees LM, An M, Qiang W. pH-dependent thermodynamic intermediates of pHLIP membrane insertion determined by solid-state NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 30442664 DOI: 10.1073/Pnas.1809190115 |
0.803 |
|
| 2017 |
Zhang A, Yao L, An M. Reversing the undesirable pH-profile of doxorubicin via activation of a di-substituted maleamic acid prodrug at tumor acidity. Chemical Communications (Cambridge, England). PMID 29143021 DOI: 10.1039/C7Cc06843C |
0.689 |
|
| 2017 |
Osonga FJ, Onyango JO, Mwilu SK, Noah NM, Schulte J, An M, Sadik OA. Synthesis and characterization of novel flavonoid derivatives via sequential phosphorylation of quercetin Tetrahedron Letters. 58: 1474-1479. DOI: 10.1016/J.Tetlet.2017.02.085 |
0.713 |
|
| 2016 |
Hanz SZ, Shu NS, Qian J, Christman N, Kranz P, An M, Grewer C, Qiang W. Protonation-Driven Membrane Insertion of a pH-Low Insertion Peptide. Angewandte Chemie (International Ed. in English). PMID 27578553 DOI: 10.1002/Anie.201605203 |
0.715 |
|
| 2016 |
An M, Klees L, Zhang A, Onyango JO, Gordon EA, Eng C, Winge-Barnes S, Lichter E, Nazarenko V, Bell MM, Bandler IG, Awad AK, Shu NS, Qiang W, Yao L. What is the Fate-Determining Step in pHLIP-Mediated Cargo Delivery? Biophysical Journal. 110: 80a. DOI: 10.1016/J.Bpj.2015.11.493 |
0.76 |
|
| 2015 |
Shu NS, Chung MS, Yao L, An M, Qiang W. Residue-specific structures and membrane locations of pH-low insertion peptide by solid-state nuclear magnetic resonance. Nature Communications. 6: 7787. PMID 26195283 DOI: 10.1038/Ncomms8787 |
0.735 |
|
| 2015 |
Onyango JO, Chung MS, Eng CH, Klees LM, Langenbacher R, Yao L, An M. Noncanonical amino acids to improve the pH response of pHLIP insertion at tumor acidity. Angewandte Chemie (International Ed. in English). 54: 3658-63. PMID 25650762 DOI: 10.1002/Anie.201409770 |
0.764 |
|
| 2014 |
Karabadzhak AG, An M, Yao L, Langenbacher R, Moshnikova A, Adochite RC, Andreev OA, Reshetnyak YK, Engelman DM. pHLIP-FIRE, a cell insertion-triggered fluorescent probe for imaging tumors demonstrates targeted cargo delivery in vivo. Acs Chemical Biology. 9: 2545-53. PMID 25184440 DOI: 10.1021/Cb500388M |
0.596 |
|
| 2014 |
Karabadzhak A, Yao L, Langenbacher R, Moshnikova A, Adochite R, An M, Andreev OA, Reshetnyak YK, Engelman DM. Phlip-Fire: A High-Contrast, Insertion-Triggered Fluorescent Probe for Targeting Tumors In Vivo Biophysical Journal. 106: 88a-89a. DOI: 10.1016/J.Bpj.2013.11.561 |
0.681 |
|
| 2014 |
An M, Onyango J, Chung MS, Lapid RJ, Gordon EA, Langenbacher R, Winge-Barnes S, Chandler RA, Engelman DM, Yao L. Towards PHLIP Insertion in the Plasmamembrane of Cancer Cells at Physiological Tumor Acidity Biophysical Journal. 106: 296a. DOI: 10.1016/J.Bpj.2013.11.1724 |
0.813 |
|
| 2014 |
Engelman DM, An M, Andreev OA, Barrera FN, Bahal R, Bosenberg MW, Cheng C, Glazer PM, Karabadzhak A, Reshetnyak YK, Saltzman WM, Slack FJ, Svoronos AA, Thevenin D. Imaging and Treating Tumors by Targeting their Acidity with Phlip, a Ph-Sensitve Insertion Peptide Biophysical Journal. 106: 231a. DOI: 10.1016/J.Bpj.2013.11.1350 |
0.789 |
|
| 2013 |
Yao L, Langenbacher R, Karabadzhak A, Engelman DM, An M. Visualizing pHLIP Insertion in Plasmamembrane and Endosomal Membrane Biophysical Journal. 104: 238a. DOI: 10.1016/J.Bpj.2012.11.1342 |
0.738 |
|
| 2011 |
Barrera FN, An M, Wijesinghe DD, Weerakkody DA, Anderson M, Andreev OA, Reshetnyak YK, Engelman DM. Abstract C2: Aspartic acid residues drive the membrane translocation of pHLIP, a therapeutic and imaging agent for solid tumors Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C2 |
0.718 |
|
| 2010 |
An M, Wijesinghe D, Andreev OA, Reshetnyak YK, Engelman DM. pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 107: 20246-50. PMID 21048084 DOI: 10.1073/Pnas.1014403107 |
0.736 |
|
| 2010 |
Thévenin D, Matthews EE, Rogers JM, An M, Gotow L, Lira PD, Reiter LA, Brissette WH, Engelman DM. Involvement of Transmembrane Helix Dimerization and Rotation in Signaling by the Thrombopoietin Receptor Biophysical Journal. 98: 420a. DOI: 10.1016/J.Bpj.2009.12.2269 |
0.728 |
|
| 2010 |
An M, Wijesinghe D, Andreev OA, Reshetnyak YK, Engelman DM. Cancer Cell Proliferation is Inhibited by Phlip Mediated Delivery of Membrane Impermeable Toxin Phalloidin Biophysical Journal. 98: 277a-278a. DOI: 10.1016/J.Bpj.2009.12.1516 |
0.613 |
|
| 2009 |
Thévenin D, An M, Engelman DM. pHLIP-mediated translocation of membrane-impermeable molecules into cells. Chemistry & Biology. 16: 754-62. PMID 19635412 DOI: 10.1016/J.Chembiol.2009.06.006 |
0.778 |
|
| 2004 |
An M, Bartlett PA. Enzymatic synthesis of a ring-contracted analogue of 5-enolpyruvylshikimate-3-phosphate. Organic Letters. 6: 4065-7. PMID 15496100 DOI: 10.1021/Ol048260Z |
0.475 |
|
| 2003 |
An M, Maitra U, Neidlein U, Bartlett PA. 5-enolpyruvylshikimate 3-phosphate synthase: chemical synthesis of the tetrahedral intermediate and assignment of the stereochemical course of the enzymatic reaction. Journal of the American Chemical Society. 125: 12759-67. PMID 14558823 DOI: 10.1021/Ja036627+ |
0.68 |
|
| 2001 |
An M, Toochinda T, Bartlett PA. Five-membered ring analogues of shikimic acid. The Journal of Organic Chemistry. 66: 1326-33. PMID 11312963 DOI: 10.1021/Jo001121K |
0.499 |
|
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