Joseph M. Simard, Ph.D. - Publications

Affiliations: 
2007 Chemistry University of Massachusetts, Amherst, Amherst, MA 
Area:
Supramolecular Chemistry, Nanotechnology

12/125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Simard JM, Szymanski B, Rotello VM. Reversible regulation of chymotrypsin activity using negatively charged gold nanoparticles featuring malonic acid termini. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 1: 153-7. PMID 16787310 DOI: 10.2174/1573406053175283  0.628
2005 Sandanaraj BS, Vutukuri DR, Simard JM, Klaikherd A, Hong R, Rotello VM, Thayumanavan S. Noncovalent modification of chymotrypsin surface using an amphiphilic polymer scaffold: implications in modulating protein function. Journal of the American Chemical Society. 127: 10693-8. PMID 16045357 DOI: 10.1021/Ja051947+  0.592
2005 Simard JM, Szymanski B, Erdogan B, Rotello VM. Control of Substrate Selectivity Through Complexation and Release of α-Chymotrypsin from Gold Nanoparticle Surfaces Journal of Biomedical Nanotechnology. 1: 341-344. DOI: 10.1166/Jbn.2005.037  0.535
2004 Verma A, Simard JM, Rotello VM. Effect of ionic strength on the binding of alpha-chymotrypsin to nanoparticle receptors. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 4178-81. PMID 15969414 DOI: 10.1021/La036183V  0.652
2004 Verma A, Simard JM, Worrall JW, Rotello VM. Tunable reactivation of nanoparticle-inhibited beta-galactosidase by glutathione at intracellular concentrations. Journal of the American Chemical Society. 126: 13987-91. PMID 15506760 DOI: 10.1021/Ja046572R  0.597
2004 Verma A, Nakade H, Simard JM, Rotello VM. Recognition and stabilization of peptide alpha-helices using templatable nanoparticle receptors. Journal of the American Chemical Society. 126: 10806-7. PMID 15339141 DOI: 10.1021/Ja047719H  0.653
2004 Verma A, Simard JM, Rotello VM. Effect of ionic strength on the binding of α-chymotrypsin to nanoparticle receptors Langmuir. 20: 4178-4181. DOI: 10.1021/la036183v  0.604
2003 Fischer NO, Verma A, Goodman CM, Simard JM, Rotello VM. Reversible "irreversible" inhibition of chymotrypsin using nanoparticle receptors. Journal of the American Chemical Society. 125: 13387-91. PMID 14583034 DOI: 10.1021/Ja0352505  0.702
2002 Fischer NO, McIntosh CM, Simard JM, Rotello VM. Inhibition of chymotrypsin through surface binding using nanoparticle-based receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 5018-23. PMID 11929986 DOI: 10.1073/Pnas.082644099  0.693
2002 Sandhu KK, McIntosh CM, Simard JM, Smith SW, Rotello VM. Gold nanoparticle-mediated transfection of mammalian cells. Bioconjugate Chemistry. 13: 3-6. PMID 11792172 DOI: 10.1021/Bc015545C  0.58
2001 McIntosh CM, Esposito EA, Boal AK, Simard JM, Martin CT, Rotello VM. Inhibition of DNA transcription using cationic mixed monolayer protected gold clusters. Journal of the American Chemical Society. 123: 7626-9. PMID 11480984 DOI: 10.1021/Ja015556G  0.64
2000 Simard J, Briggs C, Boal AK, Rotello VM. Formation and pH-controlled assembly of amphiphilic gold nanoparticles Chemical Communications. 1943-1944. DOI: 10.1039/B004162I  0.659
Low-probability matches (unlikely to be authored by this person)
2013 Woo SK, Kwon MS, Ivanov A, Geng Z, Gerzanich V, Simard JM. Complex N-glycosylation stabilizes surface expression of transient receptor potential melastatin 4b protein. The Journal of Biological Chemistry. 288: 36409-17. PMID 24214984 DOI: 10.1074/jbc.M113.530584  0.145
2015 Shen WB, Plachez C, Tsymbalyuk O, Tsymbalyuk N, Xu S, Yarnell D, Mullins R, Gulapalli R, Puche A, Simard JM, Fishman PS, Yarowsky P. Cell-based therapy in TBI: Magnetic retention of neural stem cells in vivo. Cell Transplantation. PMID 26395573 DOI: 10.3727/096368915X689550  0.109
2012 Woo SK, Kwon MS, Geng Z, Chen Z, Ivanov A, Bhatta S, Gerzanich V, Simard JM. Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 525-36. PMID 22086197 DOI: 10.1038/jcbfm.2011.159  0.103
2006 Qin K, Zhao L, Tang Y, Bhatta S, Simard JM, Zhao RY. Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes. Neuroscience. 141: 1375-88. PMID 16766127 DOI: 10.1016/j.neuroscience.2006.04.068  0.101
2015 Kwon MS, Woo SK, Kurland DB, Yoon SH, Palmer AF, Banerjee U, Iqbal S, Ivanova S, Gerzanich V, Simard JM. Methemoglobin is an endogenous toll-like receptor 4 ligand-relevance to subarachnoid hemorrhage. International Journal of Molecular Sciences. 16: 5028-46. PMID 25751721 DOI: 10.3390/Ijms16035028  0.099
2010 Simard JM, Kahle KT, Gerzanich V. Molecular mechanisms of microvascular failure in central nervous system injury--synergistic roles of NKCC1 and SUR1/TRPM4. Journal of Neurosurgery. 113: 622-9. PMID 20035575 DOI: 10.3171/2009.11.Jns081052  0.093
2012 Simard JM, Geng Z, Silver FL, Sheth KN, Kimberly WT, Stern BJ, Colucci M, Gerzanich V. Does inhibiting Sur1 complement rt-PA in cerebral ischemia? Annals of the New York Academy of Sciences. 1268: 95-107. PMID 22994227 DOI: 10.1111/j.1749-6632.2012.06705.x  0.09
2012 Walcott BP, Kahle KT, Simard JM. Novel treatment targets for cerebral edema. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 65-72. PMID 22125096 DOI: 10.1007/S13311-011-0087-4  0.085
2008 Lumpkins KM, Bochicchio GV, Keledjian K, Simard JM, McCunn M, Scalea T. Glial fibrillary acidic protein is highly correlated with brain injury. The Journal of Trauma. 65: 778-82; discussion 7. PMID 18849790 DOI: 10.1097/TA.0b013e318185db2d  0.082
2015 Mehta RI, Tosun C, Ivanova S, Tsymbalyuk N, Famakin BM, Kwon MS, Castellani RJ, Gerzanich V, Simard JM. Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts. Journal of Neuropathology and Experimental Neurology. 74: 835-49. PMID 26172285 DOI: 10.1097/NEN.0000000000000223  0.078
2014 Boggs DH, Simard JM, Steven A, Mehta MP. Potential of glyburide to reduce intracerebral edema in brain metastases. Expert Review of Neurotherapeutics. 14: 379-88. PMID 24552576 DOI: 10.1586/14737175.2014.890891  0.074
2014 Khanna A, Walcott BP, Kahle KT, Simard JM. Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans. Neurosurgical Focus. 36: E11. PMID 24380477 DOI: 10.3171/2013.10.Focus13404  0.071
2009 Kahle KT, Simard JM, Staley KJ, Nahed BV, Jones PS, Sun D. Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport. Physiology (Bethesda, Md.). 24: 257-65. PMID 19675357 DOI: 10.1152/Physiol.00015.2009  0.067
2015 Makar TK, Gerzanich V, Nimmagadda VK, Jain R, Lam K, Mubariz F, Trisler D, Ivanova S, Woo SK, Kwon MS, Bryan J, Bever CT, Simard JM. Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 12: 210. PMID 26581714 DOI: 10.1186/S12974-015-0432-3  0.066
2013 Woo SK, Kwon MS, Ivanov A, Gerzanich V, Simard JM. The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel. The Journal of Biological Chemistry. 288: 3655-67. PMID 23255597 DOI: 10.1074/jbc.M112.428219  0.065
2010 Simard JM, Woo SK, Norenberg MD, Tosun C, Chen Z, Ivanova S, Tsymbalyuk O, Bryan J, Landsman D, Gerzanich V. Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma. Science Translational Medicine. 2: 28ra29. PMID 20410530 DOI: 10.1126/scitranslmed.3000522  0.065
2012 Simard JM, Woo SK, Gerzanich V. Transient receptor potential melastatin 4 and cell death. PflüGers Archiv : European Journal of Physiology. 464: 573-82. PMID 23065026 DOI: 10.1007/s00424-012-1166-z  0.064
2009 Li M, Sun Y, Simard JM, Wang JY, Chai TC. Augmented bladder urothelial polyamine signaling and block of BK channel in the pathophysiology of overactive bladder syndrome. American Journal of Physiology. Cell Physiology. 297: C1445-51. PMID 19812367 DOI: 10.1152/ajpcell.00259.2009  0.063
2012 Costa NE, Pelotte AL, Simard JM, Syvinski CA, Deveau AM. Discovering green, aqueous suzuki coupling reactions: Synthesis of ethyl (4-phenylphenyl)acetate, a biaryl with anti-arthritic potential Journal of Chemical Education. 89: 1064-1067. DOI: 10.1021/Ed200212P  0.062
2014 Sheth KN, Kimberly WT, Elm JJ, Kent TA, Yoo AJ, Thomalla G, Campbell B, Donnan GA, Davis SM, Albers GW, Jacobson S, del Zoppo G, Simard JM, Stern BJ, Mandava P. Exploratory analysis of glyburide as a novel therapy for preventing brain swelling. Neurocritical Care. 21: 43-51. PMID 24671831 DOI: 10.1007/S12028-014-9970-2  0.062
2011 Li M, Sun Y, Simard JM, Chai TC. Increased transient receptor potential vanilloid type 1 (TRPV1) signaling in idiopathic overactive bladder urothelial cells. Neurourology and Urodynamics. 30: 606-11. PMID 21351130 DOI: 10.1002/nau.21045  0.062
2015 Stokum JA, Kurland DB, Gerzanich V, Simard JM. Mechanisms of astrocyte-mediated cerebral edema. Neurochemical Research. 40: 317-28. PMID 24996934 DOI: 10.1007/s11064-014-1374-3  0.061
2013 Mehta RI, Ivanova S, Tosun C, Castellani RJ, Gerzanich V, Simard JM. Sulfonylurea receptor 1 expression in human cerebral infarcts. Journal of Neuropathology and Experimental Neurology. 72: 871-83. PMID 23965746 DOI: 10.1097/NEN.0b013e3182a32e40  0.06
2009 Gerzanich V, Woo SK, Vennekens R, Tsymbalyuk O, Ivanova S, Ivanov A, Geng Z, Chen Z, Nilius B, Flockerzi V, Freichel M, Simard JM. De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury. Nature Medicine. 15: 185-91. PMID 19169264 DOI: 10.1038/nm.1899  0.06
2007 Yurovsky VV, Gerzanich V, Ivanova S, Dong Y, Tsymbalyuk O, Simard JM. Autocrine TGF-beta1 mediates angiotensin II-induced proliferative response of cerebral vessels in vivo. American Journal of Hypertension. 20: 950-6. PMID 17765135 DOI: 10.1016/j.amjhyper.2007.03.013  0.059
2013 Tosun C, Kurland DB, Mehta R, Castellani RJ, deJong JL, Kwon MS, Woo SK, Gerzanich V, Simard JM. Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 44: 3522-8. PMID 24114458 DOI: 10.1161/STROKEAHA.113.002904  0.059
2016 Leasure A, Kimberly WT, Sansing LH, Kahle KT, Kronenberg G, Kunte H, Simard JM, Sheth KN. Treatment of Edema Associated With Intracerebral Hemorrhage. Current Treatment Options in Neurology. 18: 9. PMID 26874842 DOI: 10.1007/S11940-015-0392-Z  0.058
2016 James RF, Kramer DR, Aljuboori ZS, Parikh G, Adams SW, Eaton JC, Al-Shaar HA, Badjatia N, Mack WJ, Simard JM. Novel Treatments in Neuroprotection for Aneurysmal Subarachnoid Hemorrhage. Current Treatment Options in Neurology. 18: 38. PMID 27325362 DOI: 10.1007/S11940-016-0421-6  0.057
2013 Kallarackal AJ, Simard JM, Bailey AM. The effect of apamin, a small conductance calcium activated potassium (SK) channel blocker, on a mouse model of neurofibromatosis 1. Behavioural Brain Research. 237: 71-5. PMID 22983217 DOI: 10.1016/j.bbr.2012.09.009  0.057
2009 Simard JM, Kilbourne M, Tsymbalyuk O, Tosun C, Caridi J, Ivanova S, Keledjian K, Bochicchio G, Gerzanich V. Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion. Journal of Neurotrauma. 26: 2257-67. PMID 19604096 DOI: 10.1089/neu.2009.1021  0.056
2013 Tosun C, Koltz MT, Kurland DB, Ijaz H, Gurakar M, Schwartzbauer G, Coksaygan T, Ivanova S, Gerzanich V, Simard JM. The protective effect of glibenclamide in a model of hemorrhagic encephalopathy of prematurity. Brain Sciences. 3: 215-38. PMID 23667741 DOI: 10.3390/brainsci3010215  0.056
2015 Martínez-Valverde T, Vidal-Jorge M, Martínez-Saez E, Castro L, Arikan F, Cordero E, Rădoi A, Poca MA, Simard JM, Sahuquillo J. Sulfonylurea Receptor 1 in Humans with Post-Traumatic Brain Contusions. Journal of Neurotrauma. 32: 1478-87. PMID 26398596 DOI: 10.1089/neu.2014.3706  0.056
2007 Sun Y, Chen M, Lowentritt BH, Van Zijl PS, Koch KR, Keay S, Simard JM, Chai TC. EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients. American Journal of Physiology. Cell Physiology. 292: C106-14. PMID 16837648 DOI: 10.1152/ajpcell.00209.2006  0.055
2013 Ryu JH, Walcott BP, Kahle KT, Sheth SA, Peterson RT, Nahed BV, Coumans JV, Simard JM. Induced and sustained hypernatremia for the prevention and treatment of cerebral edema following brain injury. Neurocritical Care. 19: 222-31. PMID 23468135 DOI: 10.1007/S12028-013-9824-3  0.053
2008 Simard JM, Castellani RJ, Ivanova S, Koltz MT, Gerzanich V. Sulfonylurea receptor 1 in the germinal matrix of premature infants. Pediatric Research. 64: 648-52. PMID 18679166 DOI: 10.1203/PDR.0b013e318186e5a9  0.052
2016 Kurland DB, Gerzanich V, Karimy JK, Woo SK, Vennekens R, Freichel M, Nilius B, Bryan J, Simard JM. The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia. Journal of Neuroinflammation. 13: 130. PMID 27246103 DOI: 10.1186/s12974-016-0599-2  0.049
2012 Simard JM, Woo SK, Schwartzbauer GT, Gerzanich V. Sulfonylurea receptor 1 in central nervous system injury: a focused review. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1699-717. PMID 22714048 DOI: 10.1038/jcbfm.2012.91  0.049
2007 Simard JM, Tsymbalyuk O, Ivanov A, Ivanova S, Bhatta S, Geng Z, Woo SK, Gerzanich V. Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury. The Journal of Clinical Investigation. 117: 2105-13. PMID 17657312 DOI: 10.1172/JCI32041  0.048
2014 Sheth KN, Kimberly WT, Elm JJ, Kent TA, Mandava P, Yoo AJ, Thomalla G, Campbell B, Donnan GA, Davis SM, Albers GW, Jacobson S, Simard JM, Stern BJ. Pilot study of intravenous glyburide in patients with a large ischemic stroke. Stroke; a Journal of Cerebral Circulation. 45: 281-3. PMID 24193798 DOI: 10.1161/Strokeaha.113.003352  0.047
2008 Lumpkins K, Bochicchio GV, Zagol B, Ulloa K, Simard JM, Schaub S, Meyer W, Scalea T. Plasma levels of the beta chemokine regulated upon activation, normal T cell expressed, and secreted (RANTES) correlate with severe brain injury. The Journal of Trauma. 64: 358-61. PMID 18301198 DOI: 10.1097/TA.0b013e318160df9b  0.047
2007 Liang D, Bhatta S, Gerzanich V, Simard JM. Cytotoxic edema: mechanisms of pathological cell swelling. Neurosurgical Focus. 22: E2. PMID 17613233  0.046
2011 Koltz MT, Tosun C, Kurland DB, Coksaygan T, Castellani RJ, Ivanova S, Gerzanich V, Simard JM. Tandem insults of prenatal ischemia plus postnatal raised intrathoracic pressure in a novel rat model of encephalopathy of prematurity. Journal of Neurosurgery. Pediatrics. 8: 628-39. PMID 22132923 DOI: 10.3171/2011.9.PEDS11174  0.045
2015 Hosier H, Peterson D, Tsymbalyuk O, Keledjian K, Smith BR, Ivanova S, Gerzanich V, Popovich PG, Simard JM. A Direct Comparison of Three Clinically Relevant Treatments in a Rat Model of Cervical Spinal Cord Injury. Journal of Neurotrauma. PMID 26192071 DOI: 10.1089/neu.2015.3892  0.045
2006 Simard JM, Gerzanich V. Sphingolipids and transient receptor potential channels: evolutionarily ancient families now joined. Circulation Research. 98: 1347-8. PMID 16763170 DOI: 10.1161/01.RES.0000228464.97010.ee  0.044
2013 Kahle KT, Walcott BP, Simard JM. Continuous hyperosmolar therapy for traumatic brain injury-associated cerebral edema: as good as it gets, or an iatrogenic secondary insult? Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 20: 30-1. PMID 23200533 DOI: 10.1016/J.Jocn.2012.10.004  0.041
2015 Zhuo J, Keledjian K, Xu S, Pampori A, Gerzanich V, Simard JM, Gullapalli RP. Changes in Diffusion Kurtosis Imaging and Magnetic Resonance Spectroscopy in a Direct Cranial Blast Traumatic Brain Injury (dc-bTBI) Model. Plos One. 10: e0136151. PMID 26301778 DOI: 10.1371/Journal.Pone.0136151  0.04
2011 Kuehn R, Simard PF, Driscoll I, Keledjian K, Ivanova S, Tosun C, Williams A, Bochicchio G, Gerzanich V, Simard JM. Rodent model of direct cranial blast injury. Journal of Neurotrauma. 28: 2155-69. PMID 21639724 DOI: 10.1089/neu.2010.1532  0.04
2009 Simard JM, Geng Z, Woo SK, Ivanova S, Tosun C, Melnichenko L, Gerzanich V. Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 317-30. PMID 18854840 DOI: 10.1038/jcbfm.2008.120  0.04
2014 Khanna A, Kahle KT, Walcott BP, Gerzanich V, Simard JM. Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema. Translational Stroke Research. 5: 3-16. PMID 24323726 DOI: 10.1007/S12975-013-0307-9  0.04
2015 Stokum JA, Gerzanich V, Simard JM. Molecular pathophysiology of cerebral edema. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661240 DOI: 10.1177/0271678X15617172  0.039
2015 Tosun C, Hong C, Carusillo B, Ivanova S, Gerzanich V, Simard JM. Angiogenesis induced by prenatal ischemia predisposes to periventricular hemorrhage during postnatal mechanical ventilation. Pediatric Research. 77: 663-73. PMID 25665055 DOI: 10.1038/pr.2015.34  0.038
2015 Stokum JA, Mehta RI, Ivanova S, Yu E, Gerzanich V, Simard JM. Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling. Acta Neuropathologica Communications. 3: 61. PMID 26419740 DOI: 10.1186/s40478-015-0239-6  0.035
2007 Simard JM, Tarasov KV, Gerzanich V. Non-selective cation channels, transient receptor potential channels and ischemic stroke. Biochimica Et Biophysica Acta. 1772: 947-57. PMID 17446049 DOI: 10.1016/j.bbadis.2007.03.004  0.035
2015 Vasilevskiy D, Simard JM, Masut RA, Turenne S. System for Simultaneous Harman-Based Measurement of All Thermoelectric Properties, from 240 to 720 K, by Use of a Novel Calibration Procedure Journal of Electronic Materials. 44: 1733-1742. DOI: 10.1007/S11664-014-3531-5  0.034
2011 Simard JM, Sahuquillo J, Sheth KN, Kahle KT, Walcott BP. Managing malignant cerebral infarction. Current Treatment Options in Neurology. 13: 217-29. PMID 21190097 DOI: 10.1007/S11940-010-0110-9  0.034
2015 Urday S, Kimberly WT, Beslow LA, Vortmeyer AO, Selim MH, Rosand J, Simard JM, Sheth KN. Targeting secondary injury in intracerebral haemorrhage--perihaematomal oedema. Nature Reviews. Neurology. 11: 111-22. PMID 25623787 DOI: 10.1038/Nrneurol.2014.264  0.032
2010 Simard JM, Schreibman D, Aldrich EF, Stallmeyer B, Le B, James RF, Beaty N. Unfractionated heparin: multitargeted therapy for delayed neurological deficits induced by subarachnoid hemorrhage. Neurocritical Care. 13: 439-49. PMID 20809188 DOI: 10.1007/s12028-010-9435-1  0.032
2007 Kunte H, Schmidt S, Eliasziw M, del Zoppo GJ, Simard JM, Masuhr F, Weih M, Dirnagl U. Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke. Stroke; a Journal of Cerebral Circulation. 38: 2526-30. PMID 17673715 DOI: 10.1161/Strokeaha.107.482216  0.029
2008 Simard JM, Woo SK, Bhatta S, Gerzanich V. Drugs acting on SUR1 to treat CNS ischemia and trauma. Current Opinion in Pharmacology. 8: 42-9. PMID 18032110 DOI: 10.1016/j.coph.2007.10.004  0.029
2015 Vasilevskiy D, Simard JM, Caillat T, Masut RA, Turenne S. Consistency of ZT-Scanner for Thermoelectric Measurements from 300 K to 700 K: A Comparative Analysis Using Si80Ge20 Polycrystalline Alloys Journal of Electronic Materials. DOI: 10.1007/S11664-015-4101-1  0.027
2006 Simard JM, Chen M, Tarasov KV, Bhatta S, Ivanova S, Melnitchenko L, Tsymbalyuk N, West GA, Gerzanich V. Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nature Medicine. 12: 433-40. PMID 16550187 DOI: 10.1038/nm1390  0.027
2015 Woodworth G, Simard JM. Letter by Woodworth and Simard Regarding Article, "Outcome Following Decompressive Hemicraniectomy for Malignant Cerebral Infarction: Ethical Considerations". Stroke; a Journal of Cerebral Circulation. 46: e245. PMID 26443827 DOI: 10.1161/STROKEAHA.115.011336  0.024
2009 Simard JM, Yurovsky V, Tsymbalyuk N, Melnichenko L, Ivanova S, Gerzanich V. Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke. Stroke; a Journal of Cerebral Circulation. 40: 604-9. PMID 19023097 DOI: 10.1161/STROKEAHA.108.522409  0.024
2016 Lucke-Wold BP, Logsdon AF, Manoranjan B, Turner RC, McConnell E, Vates GE, Huber JD, Rosen CL, Simard JM. Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review. International Journal of Molecular Sciences. 17. PMID 27049383 DOI: 10.3390/Ijms17040497  0.024
2015 Karimy JK, Kahle KT, Kurland DB, Yu E, Gerzanich V, Simard JM. A novel method to study cerebrospinal fluid dynamics in rats. Journal of Neuroscience Methods. 241: 78-84. PMID 25554415 DOI: 10.1016/J.Jneumeth.2014.12.015  0.024
2012 Simard JM, Tsymbalyuk O, Keledjian K, Ivanov A, Ivanova S, Gerzanich V. Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury. Experimental Neurology. 233: 566-74. PMID 22177998 DOI: 10.1016/j.expneurol.2011.11.044  0.024
2009 Kilbourne M, Kuehn R, Tosun C, Caridi J, Keledjian K, Bochicchio G, Scalea T, Gerzanich V, Simard JM. Novel model of frontal impact closed head injury in the rat. Journal of Neurotrauma. 26: 2233-43. PMID 19929375 DOI: 10.1089/neu.2009.0968  0.023
2015 Kunte H, Farhadi HF, Sheth KN, Simard JM, Kronenberg G. Sulfonylureas--a novel treatment to reduce tissue damage after acute spinal cord injury? The Lancet. Neurology. 14: 352. PMID 25792091 DOI: 10.1016/S1474-4422(15)70013-X  0.023
2013 Shivashankar R, Miller TR, Jindal G, Simard JM, Aldrich EF, Gandhi D. Treatment of cerebral aneurysms-surgical clipping or endovascular coiling: the guiding principles. Seminars in Neurology. 33: 476-87. PMID 24504611 DOI: 10.1055/s-0033-1364217  0.023
2007 Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V. Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. The Lancet. Neurology. 6: 258-68. PMID 17303532 DOI: 10.1016/S1474-4422(07)70055-8  0.023
2006 Iadecola C, Goldman SS, Harder DR, Heistad DD, Katusic ZS, Moskowitz MA, Simard JM, Sloan MA, Traystman RJ, Velletri PA. Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease. Stroke; a Journal of Cerebral Circulation. 37: 1578-81. PMID 16627792 DOI: 10.1161/01.Str.0000221297.57305.8A  0.023
2012 Simard JM, Tosun C, Ivanova S, Kurland DB, Hong C, Radecki L, Gisriel C, Mehta R, Schreibman D, Gerzanich V. Heparin reduces neuroinflammation and transsynaptic neuronal apoptosis in a model of subarachnoid hemorrhage. Translational Stroke Research. 3: 155-65. PMID 22707992 DOI: 10.1007/s12975-012-0166-9  0.022
2012 Kunte H, Busch MA, Trostdorf K, Vollnberg B, Harms L, Mehta RI, Castellani RJ, Mandava P, Kent TA, Simard JM. Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas. Annals of Neurology. 72: 799-806. PMID 23280795 DOI: 10.1002/Ana.23680  0.022
2014 Walcott BP, Miller JC, Kwon CS, Sheth SA, Hiller M, Cronin CA, Schwamm LH, Simard JM, Kahle KT, Kimberly WT, Sheth KN. Outcomes in severe middle cerebral artery ischemic stroke. Neurocritical Care. 21: 20-6. PMID 23839704 DOI: 10.1007/S12028-013-9838-X  0.021
2012 Simard JM, Popovich PG, Tsymbalyuk O, Gerzanich V. Spinal cord injury with unilateral versus bilateral primary hemorrhage--effects of glibenclamide. Experimental Neurology. 233: 829-35. PMID 22197047 DOI: 10.1016/j.expneurol.2011.11.048  0.021
2005 Ma L, Kwok Y, Chin LS, Simard JM, Regine WF. Concomitant GRID boost for Gamma Knife radiosurgery. Medical Physics. 32: 3419-23. PMID 16370428 DOI: 10.1118/1.2068887  0.021
2011 Simard JM, Gerzanich V. Targeting the Microvasculature in Cerebral Ischemia-Go (or Stop Going) with the Flow. Translational Stroke Research. 2: 136-7. PMID 24323619 DOI: 10.1007/s12975-011-0076-2  0.019
2013 Koltz MT, Polifka AJ, Saltos A, Slawson RG, Kwok Y, Aldrich EF, Simard JM. Long-term outcome of Gamma Knife stereotactic radiosurgery for arteriovenous malformations graded by the Spetzler-Martin classification. Journal of Neurosurgery. 118: 74-83. PMID 23082882 DOI: 10.3171/2012.9.JNS112329  0.018
2003 Gerzanich V, Ivanova S, Simard JM. Early pathophysiological changes in cerebral vessels predisposing to stroke. Clinical Hemorheology and Microcirculation. 29: 291-4. PMID 14724353  0.016
2015 Khanna A, Simard JM, Kahle KT. Progesterone in traumatic brain injury. The New England Journal of Medicine. 372: 1765-6. PMID 25923560 DOI: 10.1056/NEJMc1503138#SA2  0.016
2014 Simard JM, Sheth KN, Kimberly WT, Stern BJ, del Zoppo GJ, Jacobson S, Gerzanich V. Glibenclamide in cerebral ischemia and stroke. Neurocritical Care. 20: 319-33. PMID 24132564 DOI: 10.1007/s12028-013-9923-1  0.016
2016 Sheth KN, Simard JM, Elm J, Kronenberg G, Kunte H, Kimberly WT. Human Data Supporting Glyburide in Ischemic Stroke. Acta Neurochirurgica. Supplement. 121: 13-8. PMID 26463916 DOI: 10.1007/978-3-319-18497-5_3  0.015
2006 Ivanov A, Gerzanich V, Ivanova S, Denhaese R, Tsymbalyuk O, Simard JM. Adenylate cyclase 5 and KCa1.1 channel are required for EGFR up-regulation of PCNA in native contractile rat basilar artery smooth muscle. The Journal of Physiology. 570: 73-84. PMID 16284070 DOI: 10.1113/jphysiol.2005.100883  0.015
2013 Fortes MC, Jindal G, Polifka AJ, Aldrich EF, Simard JM, Gandhi D. Low-angle vascular access for neurovascular procedures using the Arstasis AXERA access device. Journal of Vascular and Interventional Radiology : Jvir. 24: 693-7. PMID 23489771 DOI: 10.1016/j.jvir.2013.01.012  0.015
2012 Kurland D, Hong C, Aarabi B, Gerzanich V, Simard JM. Hemorrhagic progression of a contusion after traumatic brain injury: a review. Journal of Neurotrauma. 29: 19-31. PMID 21988198 DOI: 10.1089/neu.2011.2122  0.014
2014 Hong CM, Tosun C, Kurland DB, Gerzanich V, Schreibman D, Simard JM. Biomarkers as outcome predictors in subarachnoid hemorrhage--a systematic review. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 19: 95-108. PMID 24499240 DOI: 10.3109/1354750X.2014.881418  0.012
2011 Simard JM, Kahle KT, Walcott BP. Craniectomy in diffuse traumatic brain injury. The New England Journal of Medicine. 365: 374; author reply 37. PMID 21793753 DOI: 10.1056/NEJMc1106421#SA3  0.012
2011 Simard JM, Kahle KT, Walcott BP. Craniectomy in diffuse traumatic brain injury [3] New England Journal of Medicine. 365: 374.  0.012
2012 Aarabi B, Simard JM, Kufera JA, Alexander M, Zacherl KM, Mirvis SE, Shanmuganathan K, Schwartzbauer G, Maulucci CM, Slavin J, Ali K, Massetti J, Eisenberg HM. Intramedullary lesion expansion on magnetic resonance imaging in patients with motor complete cervical spinal cord injury. Journal of Neurosurgery. Spine. 17: 243-50. PMID 22794535 DOI: 10.3171/2012.6.SPINE12122  0.012
2011 Ho M, McMillan A, Simard JM, Gullapalli R, Desai JP. Towards a Meso-Scale SMA-Actuated MRI-Compatible Neurosurgical Robot. Ieee Transactions On Robotics : a Publication of the Ieee Robotics and Automation Society. 2011: 1-10. PMID 22267960 DOI: 10.1109/TRO.2011.2165371  0.012
2010 Patel AD, Gerzanich V, Geng Z, Simard JM. Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 69: 1177-90. PMID 21107131 DOI: 10.1097/NEN.0b013e3181fbf6d6  0.011
2015 Simard JM. Essentially all models are wrong, but some are useful. Neurology. 85: 210-1. PMID 26109711 DOI: 10.1212/WNL.0000000000001769  0.011
2009 Aarabi B, Simard JM. Traumatic brain injury. Current Opinion in Critical Care. 15: 548-53. PMID 19741521 DOI: 10.1097/MCC.0b013e32833190da  0.01
2011 Simard PF, Tosun C, Melnichenko L, Ivanova S, Gerzanich V, Simard JM. Inflammation of the choroid plexus and ependymal layer of the ventricle following intraventricular hemorrhage. Translational Stroke Research. 2: 227-31. PMID 21731590 DOI: 10.1007/s12975-011-0070-8  0.01
2016 Urday S, Beslow LA, Dai F, Zhang F, Battey TW, Vashkevich A, Ayres AM, Leasure AC, Selim MH, Simard JM, Rosand J, Kimberly WT, Sheth KN. Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage. Critical Care Medicine. PMID 26757167 DOI: 10.1097/Ccm.0000000000001553  0.01
2015 Simard JM, Sheth KN. Is Glibenclamide the New Cool in Cardiopulmonary Resuscitation? Critical Care Medicine. 43: 2040-1. PMID 26274718 DOI: 10.1097/CCM.0000000000001112  0.01
2015 Kurland DB, Khaladj-Ghom A, Stokum JA, Carusillo B, Karimy JK, Gerzanich V, Sahuquillo J, Simard JM. Complications Associated with Decompressive Craniectomy: A Systematic Review. Neurocritical Care. 23: 292-304. PMID 26032808 DOI: 10.1007/s12028-015-0144-7  0.01
2015 Caffes N, Kurland DB, Gerzanich V, Simard JM. Glibenclamide for the treatment of ischemic and hemorrhagic stroke. International Journal of Molecular Sciences. 16: 4973-84. PMID 25749474 DOI: 10.3390/ijms16034973  0.01
2014 Simard JM, Pampori A, Keledjian K, Tosun C, Schwartzbauer G, Ivanova S, Gerzanich V. Exposure of the thorax to a sublethal blast wave causes a hydrodynamic pulse that leads to perivenular inflammation in the brain. Journal of Neurotrauma. 31: 1292-304. PMID 24673157 DOI: 10.1089/neu.2013.3016  0.01
2013 Simard JM, Woo SK, Aarabi B, Gerzanich V. The Sur1-Trpm4 Channel in Spinal Cord Injury. Journal of Spine. PMID 24834370 DOI: 10.4172/2165-7939.S4-002  0.01
2013 Kurland DB, Tosun C, Pampori A, Karimy JK, Caffes NM, Gerzanich V, Simard JM. Glibenclamide for the treatment of acute CNS injury. Pharmaceuticals (Basel, Switzerland). 6: 1287-303. PMID 24275850 DOI: 10.3390/ph6101287  0.01
2013 Simard JM, Koltz MT, Polifka AJ, Saltos A, Slawson RG, Kwok Y, Aldrich EF. Spetzler-Martin grade III arteriovenous malformations. Author reply. Journal of Neurosurgery. 119: 821-2. PMID 24137780 DOI: 10.3171/2012.11.JNS122231  0.01
2013 Simard JM, Popovich PG, Tsymbalyuk O, Caridi J, Gullapalli RP, Kilbourne MJ, Gerzanich V. MRI evidence that glibenclamide reduces acute lesion expansion in a rat model of spinal cord injury. Spinal Cord. 51: 823-7. PMID 24042989 DOI: 10.1038/sc.2013.99  0.01
2013 Simard JM, Aldrich EF, Schreibman D, James RF, Polifka A, Beaty N. Low-dose intravenous heparin infusion in patients with aneurysmal subarachnoid hemorrhage: a preliminary assessment. Journal of Neurosurgery. 119: 1611-9. PMID 24032706 DOI: 10.3171/2013.8.JNS1337  0.01
2013 Walcott BP, Kahle KT, Simard JM. The DECRA trial and decompressive craniectomy in diffuse traumatic brain injury: is decompression really ineffective? World Neurosurgery. 79: 80-1. PMID 23159659 DOI: 10.1016/j.wneu.2012.11.014  0.01
2012 Simard JM, Woo SK, Tsymbalyuk N, Voloshyn O, Yurovsky V, Ivanova S, Lee R, Gerzanich V. Glibenclamide-10-h Treatment Window in a Clinically Relevant Model of Stroke. Translational Stroke Research. 3: 286-95. PMID 22707989 DOI: 10.1007/s12975-012-0149-x  0.01
2012 Simard JM, Gerzanich V. When replication teaches more than the original experiment--the saga of the unknown unknown. Experimental Neurology. 233: 623-4. PMID 22078759 DOI: 10.1016/j.expneurol.2011.03.023  0.01
2011 Walcott BP, Kuklina EV, Nahed BV, George MG, Kahle KT, Simard JM, Asaad WF, Coumans JV. Craniectomy for malignant cerebral infarction: prevalence and outcomes in US hospitals. Plos One. 6: e29193. PMID 22195021 DOI: 10.1371/Journal.Pone.0029193  0.01
2011 Simard JM, Kent TA, Kunte H. Letter by Simard et al regarding article, "Sulfonylurea use before stroke does not influence outcome". Stroke; a Journal of Cerebral Circulation. 42: e409; author reply e. PMID 21597017 DOI: 10.1161/STROKEAHA.111.620666  0.01
2011 Ho M, Koltz M, Simard JM, Gullapalli R, Desai JP. Towards a MR image-guided SMA-actuated neurosurgical robot Proceedings - Ieee International Conference On Robotics and Automation. 1153-1158. DOI: 10.1109/ICRA.2011.5980320  0.01
2011 Coursol P, Coulombe P, Gosselin S, Lavoie D, Simard JM, Marks J, Fardeau S. Impact of operations at low anode-cathode distance on energy consumption and greenhouse gas emissions at Aluminerie Alouette Jom. 63: 109-115. DOI: 10.1007/s11837-011-0121-3  0.01
2010 Simard JM, Tsymbalyuk N, Tsymbalyuk O, Ivanova S, Yurovsky V, Gerzanich V. Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke. Stroke; a Journal of Cerebral Circulation. 41: 531-7. PMID 20093633 DOI: 10.1161/STROKEAHA.109.572644  0.01
2009 Aarabi B, Hesdorffer DC, Simard JM, Ahn ES, Aresco C, Eisenberg HM, McCunn M, Scalea T. Comparative study of decompressive craniectomy after mass lesion evacuation in severe head injury. Neurosurgery. 64: 927-39; discussion 9. PMID 19287327 DOI: 10.1227/01.NEU.0000341907.30831.D2  0.01
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