Yonatan H. Grad, Ph.D. - Publications

Affiliations: 
2004 Harvard University, Cambridge, MA, United States 
Area:
Computational Genetics

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ojala F, Sater MRA, Miller LG, McKinnell JA, Hayden MK, Huang SS, Grad YH, Marttinen P. Bayesian modeling of the impact of antibiotic resistance on the efficiency of MRSA decolonization. Plos Computational Biology. 19: e1010898. PMID 37883601 DOI: 10.1371/journal.pcbi.1010898  0.322
2023 Helekal D, Keeling M, Grad YH, Didelot X. Estimating the fitness cost and benefit of antimicrobial resistance from pathogen genomic data. Journal of the Royal Society, Interface. 20: 20230074. PMID 37312496 DOI: 10.1098/rsif.2023.0074  0.321
2023 Mortimer TD, Grad YH. A genomic perspective on the near-term impact of doxycycline post-exposure prophylaxis on Neisseria gonorrhoeae antimicrobial resistance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 37138444 DOI: 10.1093/cid/ciad279  0.313
2023 Mortimer TD, Grad YH. A genomic perspective on the near-term impact of doxycycline post-exposure prophylaxis on antimicrobial resistance. Medrxiv : the Preprint Server For Health Sciences. PMID 36993406 DOI: 10.1101/2023.03.14.23287223  0.335
2023 Rubin DH, Mortimer TD, Grad YH. Neisseria gonorrhoeae diagnostic escape from a gyrA-based test for ciprofloxacin susceptibility and the effect on zoliflodacin resistance: a bacterial genetics and experimental evolution study. The Lancet. Microbe. PMID 36868257 DOI: 10.1016/S2666-5247(22)00356-1  0.304
2023 Bristow CC, Mortimer TD, Morris S, Grad Y, Soge OO, Wakatake E, Pascual R, Murphy SM, Fryling KE, Adamson PC, Dillon JA, Palmer NR, Le HHL, Van Le H, Ovalles Ureña RM, et al. Whole Genome Sequencing to Predict Antimicrobial Susceptibility Profiles in Neisseria gonorrhoeae. The Journal of Infectious Diseases. PMID 36735316 DOI: 10.1093/infdis/jiad027  0.31
2023 Rubin DHF, Ma KC, Westervelt KA, Hullahalli K, Waldor MK, Grad YH. CanB is a metabolic mediator of antibiotic resistance in Neisseria gonorrhoeae. Nature Microbiology. 8: 28-39. PMID 36604513 DOI: 10.1038/s41564-022-01282-x  0.31
2022 Martin SL, Mortimer TD, Grad YH. Machine learning models for Neisseria gonorrhoeae antimicrobial susceptibility tests. Annals of the New York Academy of Sciences. PMID 36573759 DOI: 10.1111/nyas.14549  0.33
2022 Quan KA, Sater MRA, Uy C, Clifton-Koeppel R, Dickey LL, Wilson W, Patton P, Chang W, Samuelson P, Lagoudas GK, Allen T, Merchant L, Gannotta R, Bittencourt CE, Soto JC, ... ... Grad YH, et al. Epidemiology and genomics of a slow outbreak of methicillin-resistant (MRSA) in a neonatal intensive care unit: Successful chronic decolonization of MRSA-positive healthcare personnel. Infection Control and Hospital Epidemiology. 1-8. PMID 35706396 DOI: 10.1017/ice.2022.133  0.301
2021 Sánchez-Busó L, Yeats CA, Taylor B, Goater RJ, Underwood A, Abudahab K, Argimón S, Ma KC, Mortimer TD, Golparian D, Cole MJ, Grad YH, Martin I, Raphael BH, Shafer WM, et al. A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch. Genome Medicine. 13: 61. PMID 33875000 DOI: 10.1186/s13073-021-00858-2  0.322
2021 Yahara K, Ma KC, Mortimer TD, Shimuta K, Nakayama SI, Hirabayashi A, Suzuki M, Jinnai M, Ohya H, Kuroki T, Watanabe Y, Yasuda M, Deguchi T, Eldholm V, Harrison OB, ... ... Grad YH, et al. Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae. Genome Medicine. 13: 51. PMID 33785063 DOI: 10.1186/s13073-021-00860-8  0.304
2020 Olesen SW, Lipsitch M, Grad YH. The role of "spillover" in antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America. 117: 29063-29068. PMID 33139558 DOI: 10.1073/pnas.2013694117  0.314
2020 Ma KC, Mortimer TD, Duckett MA, Hicks AL, Wheeler NE, Sánchez-Busó L, Grad YH. Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae. Nature Communications. 11: 5374. PMID 33097713 DOI: 10.1038/s41467-020-19250-6  0.304
2020 Ma KC, Mortimer TD, Grad YH. Efflux Pump Antibiotic Binding Site Mutations Are Associated with Azithromycin Nonsusceptibility in Clinical Neisseria gonorrhoeae Isolates. Mbio. 11. PMID 32843551 DOI: 10.1128/Mbio.01509-20  0.363
2020 Mortimer TD, Pathela P, Crawley A, Rakeman JL, Lin Y, Harris SR, Blank S, Schillinger JA, Grad YH. The distribution and spread of susceptible and resistant Neisseria gonorrhoeae across demographic groups in a major metropolitan center. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32829411 DOI: 10.1093/Cid/Ciaa1229  0.416
2020 Ma KC, Mortimer TD, Hicks AL, Wheeler NE, Sánchez-Busó L, Golparian D, Taiaroa G, Rubin DHF, Wang Y, Williamson DA, Unemo M, Harris SR, Grad YH. Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae. Nature Communications. 11: 4126. PMID 32807804 DOI: 10.1038/S41467-020-17980-1  0.426
2020 Hicks AL, Kissler SM, Mortimer TD, Ma KC, Taiaroa G, Ashcroft M, Williamson DA, Lipsitch M, Grad YH. Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants. Elife. 9. PMID 32602459 DOI: 10.7554/Elife.56367  0.42
2020 Segal E, Zhang F, Lin X, King G, Shalem O, Shilo S, Allen WE, Alquaddoomi F, Altae-Tran H, Anders S, Balicer R, Bauman T, Bonilla X, Booman G, Chan AT, ... ... Grad YH, et al. Building an international consortium for tracking coronavirus health status. Nature Medicine. PMID 32488218 DOI: 10.1038/S41591-020-0929-X  0.305
2020 Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YH. Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study. Plos Medicine. 17: e1003077. PMID 32243443 DOI: 10.1371/Journal.Pmed.1003077  0.377
2020 Kissler SM, Klevens RM, Barnett ML, Grad YH. Distinguishing the roles of antibiotic stewardship and reductions in outpatient visits in generating a five-year decline in antibiotic prescribing. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32173727 DOI: 10.1093/Cid/Ciaa269  0.337
2020 Rubin DHF, Ross JDC, Grad YH. The frontiers of addressing antibiotic resistance in Neisseria gonorrhoeae. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32119845 DOI: 10.1016/J.Trsl.2020.02.002  0.408
2020 Volz EM, Wiuf C, Grad YH, Frost SDW, Dennis AM, Didelot X. Identification of hidden population structure in time-scaled phylogenies. Systematic Biology. PMID 32049340 DOI: 10.1093/Sysbio/Syaa009  0.345
2020 Wohl S, Metsky HC, Schaffner SF, Piantadosi A, Burns M, Lewnard JA, Chak B, Krasilnikova LA, Siddle KJ, Matranga CB, Bankamp B, Hennigan S, Sabina B, Byrne EH, McNall RJ, ... ... Grad YH, et al. Combining genomics and epidemiology to track mumps virus transmission in the United States. Plos Biology. 18: e3000611. PMID 32045407 DOI: 10.1371/Journal.Pbio.3000611  0.335
2020 Břinda K, Callendrello A, Ma KC, MacFadden DR, Charalampous T, Lee RS, Cowley L, Wadsworth CB, Grad YH, Kucherov G, O'Grady J, Baym M, Hanage WP. Rapid inference of antibiotic resistance and susceptibility by genomic neighbour typing. Nature Microbiology. PMID 32042129 DOI: 10.1038/S41564-019-0656-6  0.447
2020 Tedijanto C, Grad YH, Lipsitch M. Potential impact of outpatient stewardship interventions on antibiotic exposures of common bacterial pathogens. Elife. 9. PMID 32022685 DOI: 10.7554/Elife.52307  0.375
2020 Palace SG, Wang Y, Rubin DHF, Welsh MA, Mortimer TD, Cole K, Eyre DW, Walker S, Grad YH. RNA polymerase mutations cause cephalosporin resistance in clinical isolates. Elife. 9. PMID 32011233 DOI: 10.7554/Elife.51407  0.379
2020 Hicks AL, Kissler SM, Mortimer TD, Ma KC, Taiaroa G, Ashcroft M, Williamson DA, Lipsitch M, Grad YH. Author response: Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants Elife. DOI: 10.7554/Elife.56367.Sa2  0.364
2020 Tedijanto C, Grad YH, Lipsitch M. Author response: Potential impact of outpatient stewardship interventions on antibiotic exposures of common bacterial pathogens Elife. DOI: 10.7554/Elife.52307.Sa2  0.31
2019 Ryu S, Cowling BJ, Wu P, Olesen S, Fraser C, Sun DS, Lipsitch M, Grad YH. Case-based surveillance of antimicrobial resistance with full susceptibility profiles. Jac-Antimicrobial Resistance. 1: dlz070. PMID 32280945 DOI: 10.1093/jacamr/dlz070  0.303
2019 Coe KA, Lee W, Stone MC, Komazin-Meredith G, Meredith TC, Grad YH, Walker S. Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus. Plos Pathogens. 15: e1007862. PMID 31738809 DOI: 10.1371/Journal.Ppat.1007862  0.402
2019 Hicks AL, Kissler SM, Lipsitch M, Grad YH. Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics. Plos Biology. 17: e3000547. PMID 31714937 DOI: 10.1371/Journal.Pbio.3000547  0.359
2019 Hicks AL, Wheeler N, Sánchez-Busó L, Rakeman JL, Harris SR, Grad YH. Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data. Plos Computational Biology. 15: e1007349. PMID 31479500 DOI: 10.1371/Journal.Pcbi.1007349  0.378
2019 Sánchez-Busó L, Golparian D, Corander J, Grad YH, Ohnishi M, Flemming R, Parkhill J, Bentley SD, Unemo M, Harris SR. The impact of antimicrobials on gonococcal evolution. Nature Microbiology. PMID 31358980 DOI: 10.1038/S41564-019-0501-Y  0.374
2019 Wadsworth CB, Sater MRA, Bhattacharyya RP, Grad YH. Impact of species diversity on the design of RNA-based diagnostics for antibiotic resistance in . Antimicrobial Agents and Chemotherapy. PMID 31138575 DOI: 10.1128/Aac.00549-19  0.395
2019 Olesen SW, MacFadden D, Grad YH. Cumulative Probability of Receiving an Antibiotic Prescription over Time. The New England Journal of Medicine. 380: 1872-1873. PMID 31067381 DOI: 10.1056/Nejmc1816699  0.307
2019 Klevens RM, Caten E, Olesen SW, DeMaria A, Troppy S, Grad YH. Outpatient Antibiotic Prescribing in Massachusetts, 2011-2015. Open Forum Infectious Diseases. 6: ofz169. PMID 31065563 DOI: 10.1093/Ofid/Ofz169  0.319
2019 Olesen SW, Lipsitch M, Grad YH. Response to comment on 'The distribution of antibiotic use and its association with antibiotic resistance'. Elife. 8. PMID 31050649 DOI: 10.7554/Elife.47124  0.336
2019 Järvenpää M, Sater MRA, Lagoudas GK, Blainey PC, Miller LG, McKinnell JA, Huang SS, Grad YH, Marttinen P. A Bayesian model of acquisition and clearance of bacterial colonization incorporating within-host variation. Plos Computational Biology. 15: e1006534. PMID 31009452 DOI: 10.1371/Journal.Pcbi.1006534  0.376
2019 Olesen SW, Grad YH. Deciphering the impact of bystander selection for antibiotic resistance in Neisseria gonorrhoeae. The Journal of Infectious Diseases. PMID 30957162 DOI: 10.1093/Infdis/Jiz156  0.384
2019 Wang Y, Ferrer-Espada R, Baglo Y, Goh XS, Held KD, Grad YH, Gu Y, Gelfand JA, Dai T. Photo-inactivation of Neisseria gonorrhoeae: A paradigm changing approach for combating antibiotic-resistant gonococcal infection. The Journal of Infectious Diseases. PMID 30629196 DOI: 10.1093/Infdis/Jiz018  0.384
2019 MacFadden DR, Lipsitch M, Olesen SW, Grad Y. Multidrug-resistant Neisseria gonorrhoeae: implications for future treatment strategies. The Lancet. Infectious Diseases. 18: 599. PMID 29856349 DOI: 10.1016/S1473-3099(18)30274-3  0.356
2019 Palace SG, Wang Y, Rubin DH, Welsh MA, Mortimer TD, Cole K, Eyre DW, Walker S, Grad YH. Author response: RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates Elife. DOI: 10.7554/Elife.51407.Sa2  0.327
2019 Williamson D, Chow E, Gorrie C, Ingle D, Easton M, Seemann T, Taiaroa G, Grad Y, Kwong J, Fairley C, Chen M, Howden B. O19.2 Bridging of neisseria gonorrhoeae across diverse sexual networks in the HIV PrEP era Sexually Transmitted Infections. 95. DOI: 10.1136/Sextrans-2019-Sti.211  0.341
2019 Palace S, Wang Y, Rubin D, Grad Y. O04.1 Novel pathway to ceftriaxone resistance in clinical isolates of N. gonorrhoeae via point mutations in the RNA polymerase Sexually Transmitted Infections. 95. DOI: 10.1136/Sextrans-2019-Sti.122  0.412
2018 Olesen SW, Barnett ML, MacFadden DR, Brownstein JS, Hernández-Díaz S, Lipsitch M, Grad YH. The distribution of antibiotic use and its association with antibiotic resistance. Elife. 7. PMID 30560781 DOI: 10.7554/Elife.39435  0.385
2018 Tedijanto C, Olesen SW, Grad YH, Lipsitch M. Estimating the proportion of bystander selection for antibiotic resistance among potentially pathogenic bacterial flora. Proceedings of the National Academy of Sciences of the United States of America. 115: E11988-E11995. PMID 30559213 DOI: 10.1073/Pnas.1810840115  0.406
2018 Cristillo AD, Bristow CC, Torrone E, Dillon JA, Kirkcaldy RD, Dong H, Grad YH, Nicholas RA, Rice PA, Lawrence K, Oldach D, Shafer WM, Zhou P, Wi TE, Morris SR, et al. Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting. Sexually Transmitted Diseases. PMID 30363025 DOI: 10.1097/Olq.0000000000000929  0.39
2018 Olesen SW, Torrone EA, Papp JR, Kirkcaldy RD, Lipsitch M, Grad YH. Azithromycin susceptibility in Neisseria gonorrhoeae and seasonal macrolide use. The Journal of Infectious Diseases. PMID 30239814 DOI: 10.1093/Infdis/Jiy551  0.395
2018 Wadsworth CB, Arnold BJ, Sater MRA, Grad YH. Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae. Mbio. 9. PMID 30087172 DOI: 10.1128/Mbio.01419-18  0.442
2018 Hicks ND, Yang J, Zhang X, Zhao B, Grad YH, Liu L, Ou X, Chang Z, Xia H, Zhou Y, Wang S, Dong J, Sun L, Zhu Y, Zhao Y, et al. Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance. Nature Microbiology. PMID 30082724 DOI: 10.1038/S41564-018-0218-3  0.375
2018 Mortimer TD, Grad YH. Applications of genomics to slow the spread of multidrug-resistant Neisseria gonorrhoeae. Annals of the New York Academy of Sciences. PMID 29876934 DOI: 10.1111/Nyas.13871  0.45
2018 Arnold BJ, Gutmann MU, Grad YH, Sheppard SK, Corander J, Lipsitch M, Hanage WP. Weak Epistasis May Drive Adaptation in Recombining Bacteria. Genetics. PMID 29330348 DOI: 10.1534/Genetics.117.300662  0.312
2018 Olesen SW, Barnett ML, MacFadden DR, Brownstein JS, Hernández-Díaz S, Lipsitch M, Grad YH. Author response: The distribution of antibiotic use and its association with antibiotic resistance Elife. DOI: 10.7554/Elife.39435.018  0.374
2017 Kanjilal S, Sater MRA, Thayer M, Lagoudas GK, Kim S, Blainey PC, Grad YH. Trends in antibiotic susceptibility in Staphylococcus aureus in Boston, Massachusetts, 2000-2014. Journal of Clinical Microbiology. PMID 29093105 DOI: 10.1128/Jcm.01160-17  0.4
2017 Tuite AR, Gift TL, Chesson HW, Hsu K, Salomon JA, Grad YH. Impact of rapid susceptibility testing and antibiotic selection strategy on the emergence and spread of antibiotic resistance in gonorrhea. The Journal of Infectious Diseases. PMID 28968710 DOI: 10.1093/Infdis/Jix450  0.408
2017 Ma KC, Unemo M, Jeverica S, Kirkcaldy RD, Takahashi H, Ohnishi M, Grad YH. Genomic characterization of urethritis-associated Neisseria meningitidis shows that a wide range of N. meningitidis strains can cause urethritis. Journal of Clinical Microbiology. PMID 28904187 DOI: 10.1128/Jcm.01018-17  0.338
2017 Piantadosi A, Mukerji SS, Chitneni P, Cho TA, Cosimi LA, Hung DT, Goldberg MB, Sabeti PC, Kuritzkes DR, Grad YH. Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis. Open Forum Infectious Diseases. 4: ofx138. PMID 28761901 DOI: 10.1093/Ofid/Ofx138  0.324
2017 Eyre DW, De Silva D, Cole K, Peters J, Cole MJ, Grad YH, Demczuk W, Martin I, Mulvey MR, Crook DW, Walker AS, Peto TE, Paul J. WGS to predict antibiotic MICs for Neisseria gonorrhoeae. The Journal of Antimicrobial Chemotherapy. PMID 28333355 DOI: 10.1093/Jac/Dkx067  0.4
2017 Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, et al. Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096418 DOI: 10.1073/Pnas.1616248114  0.405
2017 Tuite A, Hsu K, Gift TL, Salomon JA, Grad YH. P3.16 Impact of rapid susceptibility profiling on the emergence and spread of antibiotic resistance in gonorrhoea Sexually Transmitted Infections. 93. DOI: 10.1136/Sextrans-2017-053264.253  0.422
2017 Kc M, Unemo M, Jeverica S, Kirkcaldy R, Ohnishi M, Grad Y. P1.59 Genomic characterisation of urethritis-associated neisseria meningitidis Sexually Transmitted Infections. 93. DOI: 10.1136/Sextrans-2017-053264.164  0.345
2017 Wadsworth C, Grad Y. P1.16 Acquisition of azithromycin resistance in neisseria gonorrhoeae via intragenus recombination Sexually Transmitted Infections. 93. DOI: 10.1136/Sextrans-2017-053264.124  0.383
2017 Kanjilal S, Sater M, Thayer M, Lagoudas G, Kim S, Blainey P, Grad YH. The Population Dynamics of Antibiotic Resistance in Staphylococcus aureus in Boston: A Return to Antibiotic Susceptibility Open Forum Infectious Diseases. 4: S639-S639. DOI: 10.1093/Ofid/Ofx163.1697  0.396
2017 Olesen S, Barnett M, MacFadden D, Lipsitch M, Grad YH. Antibiotic Consumption and Antibiotic Resistance Across Organisms, Drugs, and Consumer Groups Open Forum Infectious Diseases. 4: S18-S19. DOI: 10.1093/Ofid/Ofx162.047  0.354
2016 Johnson SR, Grad Y, Abrams AJ, Pettus K, Trees DL. Use of whole-genome sequencing data to analyze 23S rRNA-mediated azithromycin resistance. International Journal of Antimicrobial Agents. PMID 28038960 DOI: 10.1016/J.Ijantimicag.2016.10.023  0.387
2016 Grad YH, Harris SR, Kirkcaldy RD, Green AG, Marks DS, Bentley SD, Trees D, Lipsitch M. Genomic epidemiology of gonococcal resistance to extended spectrum cephalosporins, macrolides, and fluoroquinolones in the US, 2000-2013. The Journal of Infectious Diseases. PMID 27638945 DOI: 10.1093/Infdis/Jiw420  0.442
2016 Harrison OB, Clemence M, Dillard JP, Tang CM, Trees D, Grad YH, Maiden MC. Genomic analyses of Neisseria gonorrhoeae reveal an association of the gonococcal genetic island with antimicrobial resistance. The Journal of Infection. PMID 27575582 DOI: 10.1016/J.Jinf.2016.08.010  0.448
2016 Unemo M, Golparian D, Sánchez-Busó L, Grad Y, Jacobsson S, Ohnishi M, Lahra MM, Limnios A, Sikora AE, Wi T, Harris SR. The novel 2016 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations: phenotypic, genetic and reference genome characterization. The Journal of Antimicrobial Chemotherapy. PMID 27432602 DOI: 10.1093/Jac/Dkw288  0.354
2016 De Silva D, Peters J, Cole K, Cole MJ, Cresswell F, Dean G, Dave J, Thomas DR, Foster K, Waldram A, Wilson DJ, Didelot X, Grad YH, Crook DW, Peto TE, et al. Whole-genome sequencing to determine transmission of Neisseria gonorrhoeae: an observational study. The Lancet. Infectious Diseases. PMID 27427203 DOI: 10.1016/S1473-3099(16)30157-8  0.431
2016 Grad YH, Fortune SM. Biodiversity and hypervirulence of Listeria monocytogenes. Nature Genetics. 48: 229-30. PMID 26906682 DOI: 10.1038/Ng.3515  0.336
2015 Grad YH, Goldstein E, Lipsitch M, White PJ. Improving control of antibiotic resistant gonorrhea by integrating research agendas across disciplines: key questions arising from mathematical modeling. The Journal of Infectious Diseases. PMID 26518045 DOI: 10.1093/Infdis/Jiv517  0.38
2015 Chang HH, Cohen T, Grad YH, Hanage WP, O'Brien TF, Lipsitch M. Origin and proliferation of multiple-drug resistance in bacterial pathogens. Microbiology and Molecular Biology Reviews : Mmbr. 79: 101-16. PMID 25652543 DOI: 10.1128/Mmbr.00039-14  0.428
2015 Unemo M, Golparian D, Grad Y, Limnios A, Wi T, Lahra M, Harris S. P05.09 Phenotypic, genetic and genomic characterisation of the 2015 whoneisseria gonorrhoeaereference strains for quality assurance of laboratory investigations globally Sexually Transmitted Infections. 91: A111.1-A111. DOI: 10.1136/Sextrans-2015-052270.295  0.379
2015 Hollenbeck BL, Gannon S, Qian Q, Grad Y. Genome sequence and analysis of resistance and virulence determinants in a strain of Neisseria mucosa causing native-valve endocarditis Jmm Case Reports. 2. DOI: 10.1099/Jmmcr.0.000049  0.415
2014 Grad YH, Lipsitch M. Epidemiologic data and pathogen genome sequences: a powerful synergy for public health. Genome Biology. 15: 538. PMID 25418119 DOI: 10.1186/S13059-014-0538-4  0.345
2014 Johnson SR, Grad Y, Ganakammal SR, Burroughs M, Frace M, Lipsitch M, Weil R, Trees D. In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. Antimicrobial Agents and Chemotherapy. 58: 6986-9. PMID 25199775 DOI: 10.1128/Aac.03082-14  0.316
2014 Grad YH, Newman R, Zody M, Yang X, Murphy R, Qu J, Malboeuf CM, Levin JZ, Lipsitch M, DeVincenzo J. Within-host whole-genome deep sequencing and diversity analysis of human respiratory syncytial virus infection reveals dynamics of genomic diversity in the absence and presence of immune pressure. Journal of Virology. 88: 7286-93. PMID 24741088 DOI: 10.1128/Jvi.00038-14  0.324
2014 Grad YH, Kirkcaldy RD, Trees D, Dordel J, Harris SR, Goldstein E, Weinstock H, Parkhill J, Hanage WP, Bentley S, Lipsitch M. Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study. The Lancet. Infectious Diseases. 14: 220-6. PMID 24462211 DOI: 10.1016/S1473-3099(13)70693-5  0.38
2013 Grad YH, Waldor MK. Deciphering the origins and tracking the evolution of cholera epidemics with whole-genome-based molecular epidemiology. Mbio. 4: e00670-13. PMID 24023387 DOI: 10.1128/Mbio.00670-13  0.361
2013 Croucher NJ, Harris SR, Grad YH, Hanage WP. Bacterial genomes in epidemiology--present and future. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120202. PMID 23382424 DOI: 10.1098/Rstb.2012.0202  0.355
2013 Grad YH, Godfrey P, Cerquiera GC, Mariani-Kurkdjian P, Gouali M, Bingen E, Shea TP, Haas BJ, Griggs A, Young S, Zeng Q, Lipsitch M, Waldor MK, Weill FX, Wortman JR, et al. Comparative genomics of recent Shiga toxin-producing Escherichia coli O104:H4: short-term evolution of an emerging pathogen. Mbio. 4: e00452-12. PMID 23341549 DOI: 10.1128/Mbio.00452-12  0.32
2013 Grad YH, Kirkcaldy R, Trees D, Dordel J, Goldstein E, Weinstock H, Parkhill J, Hanage WP, Bentley S, Lipsitch M. O03.4 Genomic Epidemiology of Neisseria Gonorrhoeae with Reduced Susceptibility to Cefixime in the United States Sexually Transmitted Infections. 89: A31.2-A31. DOI: 10.1136/Sextrans-2013-051184.0098  0.426
2013 Grad Y, Kirkcaldy R, Dordel J, Goldstein E, Trees D, Weinstock H, Parkhill J, Hanage WP, Bentley S, Lipsitch M. YI.4 Gonococcal Genomics Shows Impact of Recombination on Obscuring Phylogenetic Signal and Disseminating Resistance Loci Sexually Transmitted Infections. 89: A25.3-A26. DOI: 10.1136/Sextrans-2013-051184.0081  0.421
2012 Grad YH, Lipsitch M, Feldgarden M, Arachchi HM, Cerqueira GC, Fitzgerald M, Godfrey P, Haas BJ, Murphy CI, Russ C, Sykes S, Walker BJ, Wortman JR, Young S, Zeng Q, et al. Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011. Proceedings of the National Academy of Sciences of the United States of America. 109: 3065-70. PMID 22315421 DOI: 10.1073/Pnas.1121491109  0.366
2004 Grad YH, Roth FP, Halfon MS, Church GM. Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura. Bioinformatics (Oxford, England). 20: 2738-50. PMID 15145800 DOI: 10.1093/Bioinformatics/Bth320  0.577
2004 Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proceedings of the National Academy of Sciences of the United States of America. 101: 360-5. PMID 14691248 DOI: 10.1073/Pnas.2333854100  0.399
2003 Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J. Computational and experimental identification of C. elegans microRNAs. Molecular Cell. 11: 1253-63. PMID 12769849 DOI: 10.1016/S1097-2765(03)00153-9  0.428
2002 Halfon MS, Grad Y, Church GM, Michelson AM. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Genome Research. 12: 1019-28. PMID 12097338 DOI: 10.1101/gr.228902  0.386
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