Amy D. Gelinas, Ph.D. - Publications

2010 Chemistry University of Colorado, Boulder, Boulder, CO, United States 
telomeres, telomerase

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ren X, Gelinas AD, Linehan M, Iwasaki A, Wang W, Janjic N, Marie Pyle A. Title: Evolving a RIG-I antagonist: a modified DNA aptamer mimics viral RNA. Journal of Molecular Biology. 167227. PMID 34487794 DOI: 10.1016/j.jmb.2021.167227  1
2020 Jankowski W, Lagassé HAD, Chang WC, McGill J, Jankowska KI, Gelinas AD, Janjic N, Sauna ZE. Modified aptamers as reagents to characterize recombinant human erythropoietin products. Scientific Reports. 10: 18593. PMID 33122796 DOI: 10.1038/s41598-020-75713-2  1
2020 Wolk SK, Mayfield WS, Gelinas AD, Astling D, Guillot J, Brody EN, Janjic N, Gold L. Modified nucleotides may have enhanced early RNA catalysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32229566 DOI: 10.1073/Pnas.1809041117  1
2019 Alexaki A, Hettiarachchi GK, Athey JC, Katneni UK, Simhadri V, Hamasaki-Katagiri N, Nanavaty P, Lin B, Takeda K, Freedberg D, Monroe D, McGill JR, Peters R, Kames JM, Holcomb DD, ... ... Gelinas A, et al. Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies. Scientific Reports. 9: 15449. PMID 31664102 DOI: 10.1038/S41598-019-51984-2  1
2017 Ren X, Gelinas AD, von Carlowitz I, Janjic N, Pyle AM. Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling. Nature Communications. 8: 810. PMID 28993621 DOI: 10.1038/S41467-017-00864-2  1
2017 Ren X, Gelinas AD, Carlowitz Iv, Janjic N, Pyle AM. Structural basis for IL-1 alpha recognition by a modified DNA aptamer that specifically inhibits IL-1 alpha signaling. Nature Communications. 8: 810-810. DOI: 10.2210/Pdb5Uc6/Pdb  1
2016 Gelinas AD, Davies DR, Janjic N. Embracing proteins: structural themes in aptamer-protein complexes. Current Opinion in Structural Biology. 36: 122-132. PMID 26919170 DOI: 10.1016/J.Sbi.2016.01.009  1
2015 Jarvis TC, Davies DR, Hisaminato A, Resnicow DI, Gupta S, Waugh SM, Nagabukuro A, Wadatsu T, Hishigaki H, Gawande B, Zhang C, Wolk SK, Mayfield WS, Nakaishi Y, Burgin AB, ... ... Gelinas AD, et al. Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure (London, England : 1993). 23: 1293-304. PMID 26027732 DOI: 10.1016/J.Str.2015.03.027  1
2014 Rohloff JC, Gelinas AD, Jarvis TC, Ochsner UA, Schneider DJ, Gold L, Janjic N. Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents. Molecular Therapy. Nucleic Acids. 3: e201. PMID 25291143 DOI: 10.1038/Mtna.2014.49  1
2014 Gelinas AD, Davies DR, Edwards TE, Rohloff JC, Carter JD, Zhang C, Gupta S, Ishikawa Y, Hirota M, Nakaishi Y, Jarvis TC, Janjic N. Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. The Journal of Biological Chemistry. 289: 8720-34. PMID 24415767 DOI: 10.1074/Jbc.M113.532697  1
2012 Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM, Wolk SK, Mayfield WS, Burgin AB, Edwards TE, Stewart LJ, Gold L, Janjic N, Jarvis TC. Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proceedings of the National Academy of Sciences of the United States of America. 109: 19971-6. PMID 23139410 DOI: 10.1073/Pnas.1213933109  1
2011 Mandell EK, Gelinas AD, Wuttke DS, Lundblad V. Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain. Biochemistry. 50: 6289-91. PMID 21668015 DOI: 10.1021/Bi2005448  1
2011 Gupta S, Thirstrup D, Jarvis TC, Schneider DJ, Wilcox SK, Carter J, Zhang C, Gelinas A, Weiss A, Janjic N, Baird GS. Rapid histochemistry using slow off-rate modified aptamers with anionic competition. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 19: 273-8. PMID 21217521 DOI: 10.1097/Pai.0B013E3182008C29  1
2009 Gelinas AD, Paschini M, Reyes FE, Héroux A, Batey RT, Lundblad V, Wuttke DS. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proceedings of the National Academy of Sciences of the United States of America. 106: 19298-303. PMID 19884503 DOI: 10.1073/Pnas.0909203106  1
2004 Gelinas AD, Toth J, Bethoney KA, Stafford WF, Harrison CJ. Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation. Journal of Molecular Biology. 339: 447-58. PMID 15136046 DOI: 10.1016/J.Jmb.2004.03.074  1
2003 Gelinas AD, Toth J, Bethoney KA, Langsetmo K, Stafford WF, Harrison CJ. Thermodynamic linkage in the GrpE nucleotide exchange factor, a molecular thermosensor. Biochemistry. 42: 9050-9. PMID 12885238 DOI: 10.1021/Bi034416B  1
2002 Gelinas AD, Langsetmo K, Toth J, Bethoney KA, Stafford WF, Harrison CJ. A structure-based interpretation of E.coli GrpE thermodynamic properties. Journal of Molecular Biology. 323: 131-42. PMID 12368105 DOI: 10.1016/S0022-2836(02)00915-4  1
2001 Toth J, Cutforth T, Gelinas AD, Bethoney KA, Bard J, Harrison CJ. Crystal structure of an ephrin ectodomain. Developmental Cell. 1: 83-92. PMID 11703926 DOI: 10.1016/S1534-5807(01)00002-8  1
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