Year |
Citation |
Score |
2023 |
Gelinas AD, Tan TK, Liu S, Jaramillo JG, Chadwick J, Harding AC, Zhang C, Ream BE, Chase CN, Otis MR, Lee T, Schneider DJ, James WS, Janjic N. Broadly neutralizing aptamers to SARS-CoV-2: a diverse panel of modified DNA antiviral agents. Molecular Therapy. Nucleic Acids. PMID 36714461 DOI: 10.1016/j.omtn.2023.01.008 |
0.349 |
|
2021 |
Ren X, Gelinas AD, Linehan M, Iwasaki A, Wang W, Janjic N, Marie Pyle A. Title: Evolving a RIG-I antagonist: a modified DNA aptamer mimics viral RNA. Journal of Molecular Biology. 167227. PMID 34487794 DOI: 10.1016/j.jmb.2021.167227 |
0.302 |
|
2019 |
Alexaki A, Hettiarachchi GK, Athey JC, Katneni UK, Simhadri V, Hamasaki-Katagiri N, Nanavaty P, Lin B, Takeda K, Freedberg D, Monroe D, McGill JR, Peters R, Kames JM, Holcomb DD, ... ... Gelinas A, et al. Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies. Scientific Reports. 9: 15449. PMID 31664102 DOI: 10.1038/S41598-019-51984-2 |
0.342 |
|
2017 |
Ren X, Gelinas AD, von Carlowitz I, Janjic N, Pyle AM. Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling. Nature Communications. 8: 810. PMID 28993621 DOI: 10.1038/S41467-017-00864-2 |
0.313 |
|
2016 |
Gelinas AD, Davies DR, Janjic N. Embracing proteins: structural themes in aptamer-protein complexes. Current Opinion in Structural Biology. 36: 122-132. PMID 26919170 DOI: 10.1016/J.Sbi.2016.01.009 |
0.468 |
|
2015 |
Jarvis TC, Davies DR, Hisaminato A, Resnicow DI, Gupta S, Waugh SM, Nagabukuro A, Wadatsu T, Hishigaki H, Gawande B, Zhang C, Wolk SK, Mayfield WS, Nakaishi Y, Burgin AB, ... ... Gelinas AD, et al. Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure (London, England : 1993). 23: 1293-304. PMID 26027732 DOI: 10.1016/J.Str.2015.03.027 |
0.426 |
|
2014 |
Rohloff JC, Gelinas AD, Jarvis TC, Ochsner UA, Schneider DJ, Gold L, Janjic N. Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents. Molecular Therapy. Nucleic Acids. 3: e201. PMID 25291143 DOI: 10.1038/Mtna.2014.49 |
0.395 |
|
2014 |
Gelinas AD, Davies DR, Edwards TE, Rohloff JC, Carter JD, Zhang C, Gupta S, Ishikawa Y, Hirota M, Nakaishi Y, Jarvis TC, Janjic N. Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. The Journal of Biological Chemistry. 289: 8720-34. PMID 24415767 DOI: 10.1074/Jbc.M113.532697 |
0.438 |
|
2012 |
Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM, Wolk SK, Mayfield WS, Burgin AB, Edwards TE, Stewart LJ, Gold L, Janjic N, Jarvis TC. Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proceedings of the National Academy of Sciences of the United States of America. 109: 19971-6. PMID 23139410 DOI: 10.1073/Pnas.1213933109 |
0.456 |
|
2011 |
Mandell EK, Gelinas AD, Wuttke DS, Lundblad V. Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain. Biochemistry. 50: 6289-91. PMID 21668015 DOI: 10.1021/Bi2005448 |
0.549 |
|
2009 |
Gelinas AD, Paschini M, Reyes FE, Héroux A, Batey RT, Lundblad V, Wuttke DS. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proceedings of the National Academy of Sciences of the United States of America. 106: 19298-303. PMID 19884503 DOI: 10.1073/Pnas.0909203106 |
0.558 |
|
2004 |
Gelinas AD, Toth J, Bethoney KA, Stafford WF, Harrison CJ. Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation. Journal of Molecular Biology. 339: 447-58. PMID 15136046 DOI: 10.1016/J.Jmb.2004.03.074 |
0.449 |
|
2003 |
Gelinas AD, Toth J, Bethoney KA, Langsetmo K, Stafford WF, Harrison CJ. Thermodynamic linkage in the GrpE nucleotide exchange factor, a molecular thermosensor. Biochemistry. 42: 9050-9. PMID 12885238 DOI: 10.1021/Bi034416B |
0.347 |
|
2002 |
Gelinas AD, Langsetmo K, Toth J, Bethoney KA, Stafford WF, Harrison CJ. A structure-based interpretation of E.coli GrpE thermodynamic properties. Journal of Molecular Biology. 323: 131-42. PMID 12368105 DOI: 10.1016/S0022-2836(02)00915-4 |
0.393 |
|
2001 |
Toth J, Cutforth T, Gelinas AD, Bethoney KA, Bard J, Harrison CJ. Crystal structure of an ephrin ectodomain. Developmental Cell. 1: 83-92. PMID 11703926 DOI: 10.1016/S1534-5807(01)00002-8 |
0.368 |
|
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