Year |
Citation |
Score |
2015 |
Cheng Y, Brown J, Judd TC, Lopez P, Qian W, Powers TS, Chen JJ, Bartberger MD, Chen K, Dunn RT, Epstein O, Fremeau RT, Harried S, Hickman D, Hitchcock SA, et al. An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities. Acs Medicinal Chemistry Letters. 6: 210-5. PMID 25699151 DOI: 10.1021/ml500458t |
0.327 |
|
2015 |
Chen JJ, Liu Q, Yuan C, Gore V, Lopez P, Ma V, Amegadzie A, Qian W, Judd TC, Minatti AE, Brown J, Cheng Y, Xue M, Zhong W, Dineen TA, et al. Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 25: 767-74. PMID 25613679 DOI: 10.1016/J.Bmcl.2014.12.092 |
0.597 |
|
2013 |
Bass PD, Gubler DA, Judd TC, Williams RM. Mitomycinoid alkaloids: mechanism of action, biosynthesis, total syntheses, and synthetic approaches. Chemical Reviews. 113: 6816-63. PMID 23654296 DOI: 10.1021/Cr3001059 |
0.5 |
|
2012 |
Kaller MR, Harried SS, Albrecht B, Amarante P, Babu-Khan S, Bartberger MD, Brown J, Brown R, Chen K, Cheng Y, Citron M, Croghan MD, Graceffa R, Hickman D, Judd T, et al. A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase. Acs Medicinal Chemistry Letters. 3: 886-91. PMID 24900403 DOI: 10.1021/Ml3000148 |
0.606 |
|
2012 |
Dineen TA, Weiss MM, Williamson T, Acton P, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dunn RT, Esmay J, Graceffa RF, Harried SS, ... ... Judd T, et al. Design and synthesis of potent, orally efficacious hydroxyethylamine derived β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 55: 9025-44. PMID 22468684 DOI: 10.1021/Jm300118S |
0.33 |
|
2012 |
Weiss MM, Williamson T, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dineen TA, Esmay J, Graceffa RF, Harried SS, Hickman D, Hitchcock SA, ... ... Judd T, et al. Design and preparation of a potent series of hydroxyethylamine containing β-secretase inhibitors that demonstrate robust reduction of central β-amyloid. Journal of Medicinal Chemistry. 55: 9009-24. PMID 22468639 DOI: 10.1021/Jm300119P |
0.304 |
|
2004 |
Judd TC, Bischoff A, Kishi Y, Adusumilli S, Small PL. Structure determination of mycolactone C via total synthesis. Organic Letters. 6: 4901-4. PMID 15606095 DOI: 10.1021/Ol0479996 |
0.452 |
|
2004 |
Judd TC, Williams RM. A concise total synthesis of (+)-FR900482 and (+)-FR66979. The Journal of Organic Chemistry. 69: 2825-30. PMID 15074934 DOI: 10.1021/Jo035828T |
0.441 |
|
2004 |
Judd TC, Williams RM. A Concise Total Synthesis of (+)-FR900482 (Ia) and (+)-FR66979 (Ib). Cheminform. 35. DOI: 10.1002/chin.200434229 |
0.42 |
|
2002 |
Judd TC, Williams RM. Concise enantioselective synthesis of (+)-FR66979 and (+)-FR900482: dimethyldioxirane-mediated construction of the hydroxylamine hemiketal. Angewandte Chemie (International Ed. in English). 41: 4683-5. PMID 12481325 DOI: 10.1002/Anie.200290015 |
0.452 |
|
2002 |
Judd TC, Williams RM. Synthesis and DNA cross-linking of a phototriggered FR900482 mitosene progenitor. Organic Letters. 4: 3711-4. PMID 12375925 DOI: 10.1021/Ol0266774 |
0.467 |
|
2000 |
Williams RM, Rollins SB, Judd TC. Synthesis of the First Photo-Triggered Pro-mitosene Based on FR-900482 Tetrahedron. 56: 521-532. DOI: 10.1016/S0040-4020(99)01046-7 |
0.489 |
|
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