Michael A. Trakselis, Ph.D. - Publications

Affiliations: 
2002 Pennsylvania State University, State College, PA, United States 
Area:
mechanistic enzymology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Khan I, Crouch JD, Bharti SK, Sommers JA, Carney SM, Yakubovskaya E, Garcia-Diaz M, Trakselis MA, Brosh RM. Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: Substrate Specificity, DNA Branch-Migration, and Ability to Overcome Blockades to DNA Unwinding. The Journal of Biological Chemistry. PMID 27226550 DOI: 10.1074/jbc.M115.712026  1
2016 Graham BW, Tao Y, Dodge KL, Thaxton CT, Olaso D, Young NL, Marshall AG, Trakselis MA. DNA Interactions Probed by H/D Exchange FT-ICR Mass Spectrometry Confirm External Binding Sites on the MCM Helicase. The Journal of Biological Chemistry. PMID 27044751 DOI: 10.1074/jbc.M116.719591  1
2015 Barnes CO, Calero M, Malik I, Graham BW, Spahr H, Lin G, Cohen AE, Brown IS, Zhang Q, Pullara F, Trakselis MA, Kaplan CD, Calero G. Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble. Molecular Cell. 59: 258-69. PMID 26186291 DOI: 10.1016/j.molcel.2015.06.034  1
2013 Mohan S, Das D, Bauer RJ, Heroux A, Zalewski JK, Heber S, Dosunmu-Ogunbi AM, Trakselis MA, Hildebrand JD, Vandemark AP. Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. Plos One. 8: e81075. PMID 24349032 DOI: 10.1371/journal.pone.0081075  1
2013 van Dongen SF, Clerx J, Nørgaard K, Bloemberg TG, Cornelissen JJ, Trakselis MA, Nelson SW, Benkovic SJ, Rowan AE, Nolte RJ. A clamp-like biohybrid catalyst for DNA oxidation. Nature Chemistry. 5: 945-51. PMID 24153373 DOI: 10.1038/nchem.1752  1
2013 Bauer RJ, Wolff ID, Zuo X, Lin HK, Trakselis MA. Assembly and distributive action of an archaeal DNA polymerase holoenzyme. Journal of Molecular Biology. 425: 4820-36. PMID 24035812 DOI: 10.1016/j.jmb.2013.09.003  1
2013 Bauer RJ, Graham BW, Trakselis MA. Novel interaction of the bacterial-Like DnaG primase with the MCM helicase in archaea. Journal of Molecular Biology. 425: 1259-73. PMID 23357171 DOI: 10.1016/j.jmb.2013.01.025  1
2012 Lin HK, Chase SF, Laue TM, Jen-Jacobson L, Trakselis MA. Differential temperature-dependent multimeric assemblies of replication and repair polymerases on DNA increase processivity. Biochemistry. 51: 7367-82. PMID 22906116 DOI: 10.1021/bi300956t  1
2012 Mohan S, Rizaldy R, Das D, Bauer RJ, Heroux A, Trakselis MA, Hildebrand JD, VanDemark AP. Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. Molecular Biology of the Cell. 23: 2131-42. PMID 22493320 DOI: 10.1091/mbc.E11-11-0937  1
2012 Bauer RJ, Begley MT, Trakselis MA. Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus. Biochemistry. 51: 1996-2007. PMID 22339170 DOI: 10.1021/bi201799a  1
2010 Zuo Z, Rodgers CJ, Mikheikin AL, Trakselis MA. Characterization of a functional DnaG-type primase in archaea: implications for a dual-primase system. Journal of Molecular Biology. 397: 664-76. PMID 20122937 DOI: 10.1016/j.jmb.2010.01.057  1
2009 Mikheikin AL, Lin HK, Mehta P, Jen-Jacobson L, Trakselis MA. A trimeric DNA polymerase complex increases the native replication processivity. Nucleic Acids Research. 37: 7194-205. PMID 19773426 DOI: 10.1093/nar/gkp767  1
2005 McGeoch AT, Trakselis MA, Laskey RA, Bell SD. Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism Nature Structural and Molecular Biology. 12: 756-762. PMID 16116441 DOI: 10.1038/nsmb974  1
2005 Trakselis MA, Alley SC, Ishmael FT. Identification and mapping of protein-protein interactions by a combination of cross-linking, cleavage, and proteomics. Bioconjugate Chemistry. 16: 741-50. PMID 16029014 DOI: 10.1021/bc050043a  0.52
2005 Norcum MT, Warrington JA, Spiering MM, Ishmael FT, Trakselis MA, Benkovic SJ. Architecture of the bacteriophage T4 primosome: electron microscopy studies of helicase (gp41) and primase (gp61). Proceedings of the National Academy of Sciences of the United States of America. 102: 3623-6. PMID 15738414 DOI: 10.1073/pnas.0500713102  1
2005 Zhang Z, Spiering MM, Trakselis MA, Ishmael FT, Xi J, Benkovic SJ, Hammes GG. Assembly of the bacteriophage T4 primosome: single-molecule and ensemble studies. Proceedings of the National Academy of Sciences of the United States of America. 102: 3254-9. PMID 15728347 DOI: 10.1073/pnas.0500327102  1
2004 Millar D, Trakselis MA, Benkovic SJ. On the solution structure of the T4 sliding clamp (gp45). Biochemistry. 43: 12723-7. PMID 15461444 DOI: 10.1021/bi048349c  1
2004 Zhuang Z, Spiering MM, Berdis AJ, Trakselis MA, Benkovic SJ. 'Screw-cap' clamp loader proteins that thread. Nature Structural & Molecular Biology. 11: 580-1. PMID 15221017 DOI: 10.1038/nsmb0704-580  1
2004 Yang J, Zhuang Z, Roccasecca RM, Trakselis MA, Benkovic SJ. The dynamic processivity of the T4 DNA polymerase during replication. Proceedings of the National Academy of Sciences of the United States of America. 101: 8289-94. PMID 15148377 DOI: 10.1073/pnas.0402625101  1
2003 Trakselis MA, Roccasecca RM, Yang J, Valentine AM, Benkovic SJ. Dissociative properties of the proteins within the bacteriophage T4 replisome. The Journal of Biological Chemistry. 278: 49839-49. PMID 14500719 DOI: 10.1074/jbc.M307405200  1
2003 Yang J, Trakselis MA, Roccasecca RM, Benkovic SJ. The application of a minicircle substrate in the study of the coordinated T4 DNA replication. The Journal of Biological Chemistry. 278: 49828-38. PMID 14500718 DOI: 10.1074/jbc.M307406200  1
2003 Trakselis MA, Berdis AJ, Benkovic SJ. Examination of the role of the clamp-loader and ATP hydrolysis in the formation of the bacteriophage T4 polymerase holoenzyme. Journal of Molecular Biology. 326: 435-51. PMID 12559912 DOI: 10.1016/S0022-2836(02)01330-X  1
2003 Ishmael FT, Trakselis MA, Benkovic SJ. Protein-protein interactions in the bacteriophage T4 replisome. The leading strand holoenzyme is physically linked to the lagging strand holoenzyme and the primosome. The Journal of Biological Chemistry. 278: 3145-52. PMID 12427736 DOI: 10.1074/jbc.M209858200  1
2001 Trakselis MA, Benkovic SJ. Intricacies in ATP-dependent clamp loading: variations across replication systems. Structure (London, England : 1993). 9: 999-1004. PMID 11709164 DOI: 10.1016/S0969-2126(01)00676-1  1
2001 Trakselis MA, Mayer MU, Ishmael FT, Roccasecca RM, Benkovic SJ. Dynamic protein interactions in the bacteriophage T4 replisome. Trends in Biochemical Sciences. 26: 566-72. PMID 11551794 DOI: 10.1016/S0968-0004(01)01929-6  1
2001 Alley SC, Trakselis MA, Mayer MU, Ishmael FT, Jones AD, Benkovic SJ. Building a replisome solution structure by elucidation of protein-protein interactions in the bacteriophage T4 DNA polymerase holoenzyme. The Journal of Biological Chemistry. 276: 39340-9. PMID 11504721 DOI: 10.1074/jbc.M104956200  1
2001 Trakselis MA, Alley SC, Abel-Santos E, Benkovic SJ. Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 98: 8368-75. PMID 11459977 DOI: 10.1073/pnas.111006698  1
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