Year |
Citation |
Score |
2013 |
Takeuchi CS, Kim BG, Blazey CM, Ma S, Johnson HW, Anand NK, Arcalas A, Baik TG, Buhr CA, Cannoy J, Epshteyn S, Joshi A, Lara K, Lee MS, Wang L, et al. Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR). Journal of Medicinal Chemistry. 56: 2218-34. PMID 23394126 DOI: 10.1021/Jm3007933 |
0.37 |
|
2012 |
Rice KD, Aay N, Anand NK, Blazey CM, Bowles OJ, Bussenius J, Costanzo S, Curtis JK, Defina SC, Dubenko L, Engst S, Joshi AA, Kennedy AR, Kim AI, Koltun ES, et al. Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973). Acs Medicinal Chemistry Letters. 3: 416-21. PMID 24900486 DOI: 10.1021/Ml300049D |
0.354 |
|
2012 |
Bussenius J, Blazey CM, Aay N, Anand NK, Arcalas A, Baik T, Bowles OJ, Buhr CA, Costanzo S, Curtis JK, DeFina SC, Dubenko L, Heuer TS, Huang P, Jaeger C, et al. Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90. Bioorganic & Medicinal Chemistry Letters. 22: 5396-404. PMID 22877636 DOI: 10.1016/J.Bmcl.2012.07.052 |
0.321 |
|
2012 |
Rice KD, Kim MH, Bussenius J, Anand NK, Blazey CM, Bowles OJ, Canne-Bannen L, Chan DS, Chen B, Co EW, Costanzo S, DeFina SC, Dubenko L, Engst S, Franzini M, et al. Pyrazolopyrimidines as dual Akt/p70S6K inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 2693-7. PMID 22450127 DOI: 10.1016/J.Bmcl.2012.03.011 |
0.377 |
|
2012 |
Bussenius J, Anand NK, Blazey CM, Bowles OJ, Bannen LC, Chan DS, Chen B, Co EW, Costanzo S, DeFina SC, Dubenko L, Engst S, Franzini M, Huang P, Jammalamadaka V, et al. Design and evaluation of a series of pyrazolopyrimidines as p70S6K inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 2283-6. PMID 22342124 DOI: 10.1016/J.Bmcl.2012.01.105 |
0.38 |
|
2002 |
Blazey CM, Heathcock CH. Regiochemistry in 1,3-dipolar cycloadditions of the azomethine ylide formed from diethyl aminomalonate and paraformaldehyde. The Journal of Organic Chemistry. 67: 298-300. PMID 11777476 DOI: 10.1021/Jo010645X |
0.324 |
|
1998 |
Tse B, Balkovec JM, Blazey CM, Hsu MJ, Nielsen J, Schmatz D. Alkyl side-chain derivatives of sordaricin as potent antifungal agents against yeast. Bioorganic & Medicinal Chemistry Letters. 8: 2269-72. PMID 9873526 DOI: 10.1016/S0960-894X(98)00401-6 |
0.315 |
|
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