Marc J. Scanio, Ph.D. - Publications

Affiliations: 
2003 Stanford University, Palo Alto, CA 
Area:
Organic, Organometallic, Bioorganic, and Medicinal Chemistry

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Scanio MJ, Shi L, Drizin I, Gregg RJ, Atkinson RN, Thomas JB, Johnson MS, Chapman ML, Liu D, Krambis MJ, Liu Y, Shieh CC, Zhang X, Simler GH, Joshi S, et al. Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain. Bioorganic & Medicinal Chemistry. 18: 7816-25. PMID 20965738 DOI: 10.1016/j.bmc.2010.09.057  0.76
2010 Kort ME, Atkinson RN, Thomas JB, Drizin I, Johnson MS, Secrest MA, Gregg RJ, Scanio MJ, Shi L, Hakeem AH, Matulenko MA, Chapman ML, Krambis MJ, Liu D, Shieh CC, et al. Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorganic & Medicinal Chemistry Letters. 20: 6812-5. PMID 20855211 DOI: 10.1016/j.bmcl.2010.08.121  0.76
2010 Wender PA, Bi FC, Gamber GG, Gosselin F, Hubbard RD, Scanio MJC, Sun R, Williams TJ, Zhang L. ChemInform Abstract: Toward the Ideal Synthesis: New Transition Metal catalyzed Reactions Inspired by Novel Medicinal Leads Cheminform. 33: no-no. DOI: 10.1002/chin.200241295  0.96
2009 Bunnelle WH, Tietje KR, Frost JM, Peters D, Ji J, Li T, Scanio MJ, Shi L, Anderson DJ, Dyhring T, Grønlien JH, Ween H, Thorin-Hagene K, Meyer MD. Octahydropyrrolo[3,4-c]pyrrole: a diamine scaffold for construction of either alpha4beta2 or alpha7-selective nicotinic acetylcholine receptor (nAChR) ligands. Substitutions that switch subtype selectivity. Journal of Medicinal Chemistry. 52: 4126-41. PMID 19552432 DOI: 10.1021/jm900249k  0.76
2008 Drizin I, Gregg RJ, Scanio MJ, Shi L, Gross MF, Atkinson RN, Thomas JB, Johnson MS, Carroll WA, Marron BE, Chapman ML, Liu D, Krambis MJ, Shieh CC, Zhang X, et al. Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain. Bioorganic & Medicinal Chemistry. 16: 6379-86. PMID 18501613 DOI: 10.1016/j.bmc.2008.05.003  0.76
2008 Kort ME, Drizin I, Gregg RJ, Scanio MJ, Shi L, Gross MF, Atkinson RN, Johnson MS, Pacofsky GJ, Thomas JB, Carroll WA, Krambis MJ, Liu D, Shieh CC, Zhang X, et al. Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain. Journal of Medicinal Chemistry. 51: 407-16. PMID 18176998 DOI: 10.1021/jm070637u  0.76
2008 McGaraughty S, Chu KL, Scanio MJ, Kort ME, Faltynek CR, Jarvis MF. A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats. The Journal of Pharmacology and Experimental Therapeutics. 324: 1204-11. PMID 18089840 DOI: 10.1124/jpet.107.134148  0.76
2002 Wender PA, Pedersen TM, Scanio MJ. Transition metal-catalyzed hetero-[5 + 2] cycloadditions of cyclopropyl imines and alkynes: dihydroazepines from simple, readily available starting materials. Journal of the American Chemical Society. 124: 15154-5. PMID 12487573 DOI: 10.1021/ja0285013  0.76
2002 Wender PA, Bi FC, Gamber GG, Gosselin F, Hubbard RD, Scanio MJC, Sun R, Williams TJ, Zhang L. Toward the ideal synthesis. New transition metal-catalyzed reactions inspired by novel medicinal leads Pure and Applied Chemistry. 74: 25-31. DOI: 10.1351/pac200274010025  0.96
2001 Wender PA, Gamber GG, Scanio MJC. Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials. Angewandte Chemie (International Ed. in English). 40: 3895-3897. PMID 29712128 DOI: 10.1002/1521-3773(20011015)40:20<3895::AID-ANIE3895>3.0.CO;2-#  0.96
2001 Wender PA, Gamber GG, Scanio MJ. Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials This research was supported by grant CHE-9800445 from the National Science Foundation. The Stanford Graduate Fellowship (M.J.C.S. and G.G.G.) is gratefully acknowledged. Angewandte Chemie (International Ed. in English). 40: 3895-3897. PMID 11668567 DOI: 10.1002/1521-3773(20011015)40:20<3895::AID-ANIE3895>3.0.CO;2-#  0.76
2000 Wender PA, Dyckman AJ, Husfeld CO, Scanio MJ. A new and practical five-carbon component for metal-catalyzed Organic Letters. 2: 1609-11. PMID 10841491  0.96
2000 Wender PA, Dyckman AJ, Husfeld CO, Scanio MJC. A New and Practical Five-Carbon Component for Metal-Catalyzed [5 + 2] Cycloadditions: Preparative Scale Syntheses of Substituted Cycloheptenones Organic Letters. 2: 1609-1611.  0.76
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