Nyssa L. Puskar, Ph.D. - Related publications

2012 Chemistry California Institute of Technology, Pasadena, CA 
physical organic chemistry to systems of biological importance
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Becerra GP, Rojas-Rodríguez F, Ramírez D, Loaiza AE, Tobar-Tosse F, Mejía SM, González J. Structural and functional computational analysis of nicotine analogs as potential neuroprotective compounds in Parkinson disease. Computational Biology and Chemistry. 86: 107266. PMID 32388154 DOI: 10.1016/j.compbiolchem.2020.107266   
2020 Perniss A, Latz A, Boseva I, Papadakis T, Dames C, Meisel C, Meisel A, Scholze P, Kummer W, Krasteva-Christ G. Acute nicotine administration stimulates ciliary activity via α3β4 nAChR in the mouse trachea. International Immunopharmacology. 84: 106496. PMID 32304995 DOI: 10.1016/j.intimp.2020.106496   
2020 Gharpure A, Noviello CM, Hibbs RE. Progress in nicotinic receptor structural biology. Neuropharmacology. 171: 108086. PMID 32272141 DOI: 10.1016/j.neuropharm.2020.108086   
2020 Picciotto MR, Kenny PJ. Mechanisms of Nicotine Addiction. Cold Spring Harbor Perspectives in Medicine. PMID 32341069 DOI: 10.1101/cshperspect.a039610   
2020 Rehan M, Ahmad E, Beg MA. Structural binding perspectives of a major tobacco alkaloid, nicotine, and its metabolite cotinine with sex-steroid nuclear receptors. Journal of Applied Toxicology : Jat. PMID 32346888 DOI: 10.1002/jat.3993   
2020 McHugh M, Williams P, Verma S, Powell-Coffman JA, Robertson AP, Martin RJ. Cholinergic receptors on intestine cells of Ascaris suum and activation of nAChRs by levamisole. International Journal For Parasitology. Drugs and Drug Resistance. 13: 38-50. PMID 32470835 DOI: 10.1016/j.ijpddr.2020.04.002   
2020 Xiang D, Xu X, Zhou Q, Yan R, Chen M, Guo Y, Zhu G. The expression of soluble functional α7-nicotinic acetylcholine receptors in E. coli and its high-affinity binding to neonicotinoid pesticides. Pesticide Biochemistry and Physiology. 164: 237-241. PMID 32284132 DOI: 10.1016/j.pestbp.2020.02.002   
2020 Changeux JP. Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor. Biomolecules. 10. PMID 32260196 DOI: 10.3390/biom10040547   
2020 Wang X, Bell IM, Uslaner JM. Activators of α7 nAChR as Potential Therapeutics for Cognitive Impairment. Current Topics in Behavioral Neurosciences. PMID 32451955 DOI: 10.1007/7854_2020_140   
2020 Choudhary S, Buxton SK, Puttachary S, Verma S, Mair GR, McCoy CJ, Reaves BJ, Wolstenholme AJ, Martin RJ, Robertson AP. EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor. Plos Pathogens. 16: e1008396. PMID 32243475 DOI: 10.1371/journal.ppat.1008396   
2020 Donat CK, Hansen HH, Hansen HD, Mease RC, Horti AG, Pomper MG, L'Estrade ET, Herth MM, Peters D, Knudsen GM, Mikkelsen JD. In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [I]Iodo-ASEM and [F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors. Molecules (Basel, Switzerland). 25. PMID 32245032 DOI: 10.3390/molecules25061425   
2020 da Costa Couto ARGM, Price KL, Mesoy S, Capes E, Lummis SCR. The M4 Helix Is Involved in α7 nACh Receptor Function. Acs Chemical Neuroscience. PMID 32364364 DOI: 10.1021/acschemneuro.0c00027   
2020 Vulfius CA, Lebedev DS, Kryukova EV, Kudryavtsev DS, Kolbaev SN, Utkin YN, Tsetlin VI. PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis. Journal of Neurochemistry. PMID 32248535 DOI: 10.1111/jnc.15020   
2020 Mohan MK, Abraham N, R P R, Jayaseelan BF, Ragnarsson L, Lewis RJ, Sarma SP. Structure and allosteric activity of a single disulfide conopeptide from at human α3β4 and α7 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. PMID 32234761 DOI: 10.1074/jbc.RA119.012098   
2020 Patel RN, Richards DP, Duce IR, Birkett MA, Sattelle DB, Mellor IR. Actions on mammalian and insect nicotinic acetylcholine receptors of harmonine-containing alkaloid extracts from the harlequin ladybird Harmonia axyridis. Pesticide Biochemistry and Physiology. 166: 104561. PMID 32448416 DOI: 10.1016/j.pestbp.2020.104561   
2020 Nikiforuk A, Litwa E, Krawczyk M, Popik P, Arias H. Desformylflustrabromine, a positive allosteric modulator of α4β2-containing nicotinic acetylcholine receptors, enhances cognition in rats. Pharmacological Reports : Pr. PMID 32207091 DOI: 10.1007/s43440-020-00092-4   
2020 Du X, Tang Y, Han Y, Ri S, Kim T, Ju K, Shi W, Sun S, Zhou W, Liu G. Acetylcholine suppresses phagocytosis via binding to muscarinic- and nicotinic-acetylcholine receptors and subsequently interfering Ca- and NFκB-signaling pathways in blood clam. Fish & Shellfish Immunology. PMID 32320762 DOI: 10.1016/j.fsi.2020.04.030   
2020 Rahman MM, Teng J, Worrell BT, Noviello CM, Lee M, Karlin A, Stowell MHB, Hibbs RE. Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. Neuron. PMID 32275860 DOI: 10.1016/j.neuron.2020.03.012   
2020 Prevost MS, Bouchenaki H, Barilone N, Gielen M, Corringer PJ. Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors. Cellular and Molecular Life Sciences : Cmls. PMID 32472188 DOI: 10.1007/s00018-020-03558-z   
2020 Furuya WI, Bassi M, Menani JV, Colombari E, Zoccal DB, Colombari DSA. Modulation of hypercapnic respiratory response by cholinergic transmission in the commissural nucleus of the solitary tract. Pflugers Archiv : European Journal of Physiology. 472: 49-60. PMID 31884528 DOI: 10.1007/s00424-019-02341-9   
2020 Shan T, Zhang H, Chen C, Chen A, Shi X, Gao X. Low expression levels of nicotinic acetylcholine receptor subunits Boα1 and Boβ1 are associated with imidacloprid resistance in Bradysia odoriphaga. Pest Management Science. PMID 32285608 DOI: 10.1002/ps.5854   
2020 Osipov AV, Terpinskaya TI, Yanchanka T, Balashevich T, Zhmak MN, Tsetlin VI, Utkin YN. α-Conotoxins Enhance both the In Vivo Suppression of Ehrlich carcinoma Growth and In Vitro Reduction in Cell Viability Elicited by Cyclooxygenase and Lipoxygenase Inhibitors. Marine Drugs. 18. PMID 32272633 DOI: 10.3390/md18040193   
2020 Wang J, Ma H, Zuo Y, Yang Y, Wu Y. CRISPR-mediated gene knockout reveals nicotinic acetylcholine receptor (nAChR) subunit α6 as a target of spinosyns in Helicoverpa armigera. Pest Management Science. PMID 32384223 DOI: 10.1002/ps.5889   
2020 Rudell JC, Borges LS, Yarov-Yarovoy V, Ferns M. The MX-Helix of Muscle nAChR Subunits Regulates Receptor Assembly and Surface Trafficking. Frontiers in Molecular Neuroscience. 13: 48. PMID 32265653 DOI: 10.3389/fnmol.2020.00048   
2020 Zhu Z, Yi F, Epplin MP, Liu D, Summer SL, Mizu R, Shaulsky G, XiangWei W, Tang W, Burger PB, Menaldino DS, Myers SJ, Liotta DC, Hansen KB, Yuan H, et al. Negative allosteric modulation of GluN1/GluN3 NMDA receptors. Neuropharmacology. 108117. PMID 32389749 DOI: 10.1016/j.neuropharm.2020.108117   
2020 Datta S, Singh S, Govindarajan R. Retrospective Analysis of Eculizumab in Patients with Acetylcholine Receptor Antibody-Negative Myasthenia Gravis: A Case Series. Journal of Neuromuscular Diseases. PMID 32444555 DOI: 10.3233/JND-190464   
2020 Stojakovic A, Ahmad SM, Malhotra S, Afzal Z, Ahmed M, Lutfy K. The role of pituitary adenylyl cyclase-activating polypeptide in the motivational effects of addictive drugs. Neuropharmacology. 108109. PMID 32325064 DOI: 10.1016/j.neuropharm.2020.108109   
2020 Bennett KA, Christopher JA, Tehan BG. Structure-based discovery and development of metabotropic glutamate receptor 5 negative allosteric modulators. Advances in Pharmacology (San Diego, Calif.). 88: 35-58. PMID 32416871 DOI: 10.1016/bs.apha.2020.03.001   
2020 Grooms AJ, Neal JF, Ng KC, Zhao W, Flood AH, Allen HC. Thermodynamic Signatures of the Origin of Anti-Hofmeister Selectivity for Phosphate at Aqueous Interfaces. The Journal of Physical Chemistry. A. PMID 32441942 DOI: 10.1021/acs.jpca.0c02515   
2020 Hendrikse ER, Liew LP, Bower RL, Bonnet M, Jamaluddin MA, Prodan N, Richards KD, Walker CS, Pairaudeau G, Smith DM, Rujan RM, Sudra R, Reynolds CA, Booe JM, Pioszak AA, et al. Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors. Acs Pharmacology & Translational Science. 3: 305-320. PMID 32296770 DOI: 10.1021/acsptsci.9b00108   
2020 Soto P, Gaete PS, Fuentes C, Lozano B, Naulin PA, Figueroa XF, Barrera NP. Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HTA Receptors. Frontiers in Cellular Neuroscience. 14: 106. PMID 32431598 DOI: 10.3389/fncel.2020.00106   
2020 Wang Y, Joseph J, Gao Y, Hu B, Geng X, Wu D, Wang J, Zhang F. Revealing the Interaction Modes of 5-HT2A Receptor Antagonists and the Structure-Based Virtual Screening from FDA and TCMNP Database. Journal of Biomolecular Structure & Dynamics. 1-20. PMID 32406337 DOI: 10.1080/07391102.2020.1768900   
2020 Gao J, Chang Z, Tian R, Li P, Ahmad F, Jia X, Liang Q, Zhao X. Reversible and site-specific immobilization of β-adrenergic receptor by aptamer-directed method for receptor-drug interaction analysis. Journal of Chromatography. A. 461091. PMID 32376022 DOI: 10.1016/j.chroma.2020.461091   
2020 Park J, Langmead CJ, Riddy DM. New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery. Acs Pharmacology & Translational Science. 3: 88-106. PMID 32259091 DOI: 10.1021/acsptsci.9b00075   
2020 Neumann A, Engel V, Mahardhika AB, Schoeder CT, Namasivayam V, Kieć-Kononowicz K, Müller CE. Computational Investigations on the Binding Mode of Ligands for the Cannabinoid-Activated G Protein-Coupled Receptor GPR18. Biomolecules. 10. PMID 32365486 DOI: 10.3390/biom10050686   
2020 Liu C, Xia L, Fu K, Cao X, Yan W, Cheng J, Roux T, Peletier LA, Yin X, Guo D. Revisit ligand-receptor interaction at the human vasopressin V receptor: A kinetic perspective. European Journal of Pharmacology. 173157. PMID 32360346 DOI: 10.1016/j.ejphar.2020.173157   
2020 Gingell JJ, Rees TA, Hendrikse ER, Siow A, Rennison D, Scotter J, Harris PWR, Brimble MA, Walker CS, Hay DL. Distinct Patterns of Internalization of Different Calcitonin Gene-Related Peptide Receptors. Acs Pharmacology & Translational Science. 3: 296-304. PMID 32296769 DOI: 10.1021/acsptsci.9b00089   
2020 Liang YL, Belousoff MJ, Fletcher MM, Zhang X, Khoshouei M, Deganutti G, Koole C, Furness SGB, Miller LJ, Hay DL, Christopoulos A, Reynolds CA, Danev R, Wootten D, Sexton PM. Structure and Dynamics of Adrenomedullin Receptors AM and AM Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins. Acs Pharmacology & Translational Science. 3: 263-284. PMID 32296767 DOI: 10.1021/acsptsci.9b00080   
2020 Hellyer SD, Aggarwal S, Chen AN, Leach K, Lapinsky DJ, Gregory KJ. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. Acs Chemical Neuroscience. PMID 32396330 DOI: 10.1021/acschemneuro.0c00009   
2020 Stegemann A, Flis D, Ziolkowski W, Distler JHW, Steinbrink K, Böhm M. The α7 nicotinic acetylcholine receptor - a promising target for the treatment of fibrotic skin disorders. The Journal of Investigative Dermatology. PMID 32335129 DOI: 10.1016/j.jid.2020.04.006   
2020 Ngo T, Stephens BS, Gustavsson M, Holden LG, Abagyan R, Handel TM, Kufareva I. Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity. Plos Biology. 18: e3000656. PMID 32271748 DOI: 10.1371/journal.pbio.3000656   
2020 Abbas H, Borde P, Willars GB, Ferry DR, Safrany ST. Hazards of Using When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors. Frontiers in Pharmacology. 11: 309. PMID 32231573 DOI: 10.3389/fphar.2020.00309   
2020 Torres-Huerta A, Chan TG, White AJP, Vilar R. Molecular recognition of bisphosphonate-based drugs by di-zinc receptors in aqueous solution and on gold nanoparticles. Dalton Transactions (Cambridge, England : 2003). PMID 32314772 DOI: 10.1039/d0dt00930j   
2020 Christie AE, Hull JJ, Dickinson PS. Assessment and comparison of putative amine receptor complement/diversity in the brain and eyestalk ganglia of the lobster, Homarus americanus. Invertebrate Neuroscience : In. 20: 7. PMID 32215729 DOI: 10.1007/s10158-020-0239-5   
2020 Pandey S, Maharana J, Li XX, Woodruff TM, Shukla AK. Emerging Insights into the Structure and Function of Complement C5a Receptors. Trends in Biochemical Sciences. PMID 32402749 DOI: 10.1016/j.tibs.2020.04.004   
2020 Lü S, Jiang M, Tian X, Hong S, Zhang J, Zhang Y. Characterization of an A-Type Muscarinic Acetylcholine Receptor and Its Possible Non-neuronal Role in the Oriental Armyworm, Walker (Lepidoptera: Noctuidae). Frontiers in Physiology. 11: 400. PMID 32425811 DOI: 10.3389/fphys.2020.00400   
2020 Tian M, Abdelrahman A, Baqi Y, Fuentes E, Azazna D, Spanier C, Densborn S, Hinz S, Schmid R, Müller CE. Discovery and structure-relationships of salicylanilide derivatives as potent, non-acidic P2X1 receptor antagonists. Journal of Medicinal Chemistry. PMID 32345019 DOI: 10.1021/acs.jmedchem.0c00435   
2020 Brizzi A, Aiello F, Boccella S, Cascio MG, De Petrocellis L, Frosini M, Gado F, Ligresti A, Luongo L, Marini P, Mugnaini C, Pessina F, Corelli F, Maione S, Manera C, et al. Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity. Bioorganic & Medicinal Chemistry. 115513. PMID 32340793 DOI: 10.1016/j.bmc.2020.115513   
2020 Del Bello F, Bonifazi A, Giorgioni G, Piergentili A, Sabbieti MG, Agas D, Dell'Aera M, Matucci R, Górecki M, Pescitelli G, Vistoli G, Quaglia W. Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus. Journal of Medicinal Chemistry. PMID 32374602 DOI: 10.1021/acs.jmedchem.9b02100   
2020 Fuller PJ, Yao YZ, Yang J, Young MJ. Structural determinants of activation of the mineralocorticoid receptor: an evolutionary perspective. Journal of Human Hypertension. PMID 32467588 DOI: 10.1038/s41371-020-0360-2