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Jonathan E. McDunn, Ph.D. - Publications

Affiliations: 
2003 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
catalytic antibodies
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Zeng C, Vangveravong S, McDunn JE, Hawkins WG, Mach RH. Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer. British Journal of Cancer. 109: 2368-77. PMID 24104966 DOI: 10.1038/Bjc.2013.593  0.303
2012 Szabova L, Yin C, Bupp S, Guerin TM, Schlomer JJ, Householder DB, Baran ML, Yi M, Song Y, Sun W, McDunn JE, Martin PL, Van Dyke T, Difilippantonio S. Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer. Cancer Research. 72: 4141-53. PMID 22617326 DOI: 10.1158/0008-5472.Can-11-3834  0.304
2012 Spitzer D, Simon PO, Kashiwagi H, Xu J, Zeng C, Vangveravong S, Zhou D, Chang K, McDunn JE, Hornick JR, Goedegebuure P, Hotchkiss RS, Mach RH, Hawkins WG. Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling. Cancer Research. 72: 201-9. PMID 22065721 DOI: 10.1158/0008-5472.Can-11-1354  0.35
2010 Spitzer D, McDunn JE, Plambeck-Suess S, Goedegebuure PS, Hotchkiss RS, Hawkins WG. A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing. Molecular Cancer Therapeutics. 9: 2142-51. PMID 20571073 DOI: 10.1158/1535-7163.Mct-10-0225  0.353
2010 Feng Y, McDunn JE, Teitelbaum DH. Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G833-41. PMID 20299605 DOI: 10.1152/Ajpgi.00030.2010  0.312
2010 Unsinger J, McGlynn M, Kasten KR, Hoekzema AS, Watanabe E, Muenzer JT, McDonough JS, Tschoep J, Ferguson TA, McDunn JE, Morre M, Hildeman DA, Caldwell CC, Hotchkiss RS. IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis. Journal of Immunology (Baltimore, Md. : 1950). 184: 3768-79. PMID 20200277 DOI: 10.4049/Jimmunol.0903151  0.32
2010 Bradfute SB, Swanson PE, Smith MA, Watanabe E, McDunn JE, Hotchkiss RS, Bavari S. Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 184: 327-35. PMID 20028660 DOI: 10.4049/Jimmunol.0901231  0.345
2010 Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Chang K, Osborne DF, Clark AT, Coopersmith CM, McDunn JE, Hotchkiss RS. IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis. Journal of Immunology (Baltimore, Md. : 1950). 184: 1401-9. PMID 20026737 DOI: 10.4049/Jimmunol.0902307  0.307
2010 McConnell KW, McDunn JE, Clark AT, Dunne WM, Dixon DJ, Turnbull IR, Dipasco PJ, Osberghaus WF, Sherman B, Martin JR, Walter MJ, Cobb JP, Buchman TG, Hotchkiss RS, Coopersmith CM. Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses. Critical Care Medicine. 38: 223-41. PMID 19770740 DOI: 10.1097/Ccm.0B013E3181B4A76B  0.301
2009 Hotchkiss RS, Strasser A, McDunn JE, Swanson PE. Cell death. The New England Journal of Medicine. 361: 1570-83. PMID 19828534 DOI: 10.1056/Nejmra0901217  0.322
2009 Simon PO, McDunn JE, Kashiwagi H, Chang K, Goedegebuure PS, Hotchkiss RS, Hawkins WG. Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma. International Journal of Cancer. Journal International Du Cancer. 125: 942-51. PMID 19405118 DOI: 10.1002/Ijc.24424  0.351
2009 McDunn JE, Muenzer JT, Dunne B, Zhou A, Yuan K, Hoekzema A, Hilliard C, Chang KC, Davis CG, McDonough J, Hunt C, Grigsby P, Piwnica-Worms D, Hotchkiss RS. An anti-apoptotic peptide improves survival in lethal total body irradiation. Biochemical and Biophysical Research Communications. 382: 657-62. PMID 19303399 DOI: 10.1016/J.Bbrc.2009.03.080  0.324
2009 Watanabe E, Muenzer JT, Hawkins WG, Davis CG, Dixon DJ, McDunn JE, Brackett DJ, Lerner MR, Swanson PE, Hotchkiss RS. Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 549-61. PMID 19188912 DOI: 10.1038/Labinvest.2009.8  0.327
2009 Brahmamdam P, Watanabe E, Unsinger J, Chang KC, Schierding W, Hoekzema AS, Zhou TT, McDonough JS, Holemon H, Heidel JD, Coopersmith CM, McDunn JE, Hotchkiss RS. Targeted delivery of siRNA to cell death proteins in sepsis. Shock (Augusta, Ga.). 32: 131-9. PMID 19033888 DOI: 10.1097/Shk.0B013E318194Bcee  0.337
2008 Peck-Palmer OM, Unsinger J, Chang KC, Davis CG, McDunn JE, Hotchkiss RS. Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival. Journal of Leukocyte Biology. 83: 1009-18. PMID 18211965 DOI: 10.1189/Jlb.0807528  0.375
2008 Schwulst SJ, Muenzer JT, Peck-Palmer OM, Chang KC, Davis CG, McDonough JS, Osborne DF, Walton AH, Unsinger J, McDunn JE, Hotchkiss RS. Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis. Shock (Augusta, Ga.). 30: 127-34. PMID 18197142 DOI: 10.1097/Shk.0B013E318162Cf17  0.335
2008 McDunn JE, Muenzer JT, Rachdi L, Chang KC, Davis CG, Dunne WM, Piwnica-Worms D, Bernal-Mizrachi E, Hotchkiss RS. Peptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 561-8. PMID 17855622 DOI: 10.1096/Fj.07-8283Com  0.331
2008 Simon PO, McDunn J, Kashiwagi H, Johnston F, Hamilton N, Linehan D, Hotchkiss R, Mach R, Hawkins W. QS306. A Pancreas Cancer Targeted Akt Inhibitor Induces Apoptosis Journal of Surgical Research. 144: 388-389. DOI: 10.1016/J.Jss.2007.12.558  0.317
2008 Brahmamdam P, Chang KC, Zeidan RK, Rele SM, Liang Y, Liu JY, Heidel JD, McDunn JE, Coopersmith CM, Hotchkiss RS. siRNA targeted at pro-apoptotic proteins, PUMA and BIM, inhibits sepsis-induced lymphocyte apoptosis Journal of the American College of Surgeons. 207: S34. DOI: 10.1016/J.Jamcollsurg.2008.06.063  0.312
2007 Kashiwagi H, McDunn JE, Simon PO, Goedegebuure PS, Xu J, Jones L, Chang K, Johnston F, Trinkaus K, Hotchkiss RS, Mach RH, Hawkins WG. Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy. Molecular Cancer. 6: 48. PMID 17631687 DOI: 10.1186/1476-4598-6-48  0.33
2007 McConnell KW, Muenzer JT, Chang KC, Davis CG, McDunn JE, Coopersmith CM, Hilliard CA, Hotchkiss RS, Grigsby PW, Hunt CR. Anti-apoptotic peptides protect against radiation-induced cell death. Biochemical and Biophysical Research Communications. 355: 501-7. PMID 17307150 DOI: 10.1016/J.Bbrc.2007.01.180  0.314
2007 Kashiwagi H, McDunn JE, Goedegebuure PS, Gaffney MC, Chang K, Trinkaus K, Piwnica-Worms D, Hotchkiss RS, Hawkins WG. TAT-Bim induces extensive apoptosis in cancer cells. Annals of Surgical Oncology. 14: 1763-71. PMID 17206479 DOI: 10.1245/S10434-006-9298-Z  0.357
2006 Hotchkiss RS, McConnell KW, Bullok K, Davis CG, Chang KC, Schwulst SJ, Dunne JC, Dietz GP, Bähr M, McDunn JE, Karl IE, Wagner TH, Cobb JP, Coopersmith CM, Piwnica-Worms D. TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 176: 5471-7. PMID 16622015 DOI: 10.4049/Jimmunol.176.9.5471  0.336
2002 Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science (New York, N.Y.). 298: 2195-9. PMID 12434011 DOI: 10.1126/Science.1077642  0.431
2001 Worrall DS, McDunn JE, List B, Reichart D, Hevener A, Gustafson T, Barbas CF, Lerner RA, Olefsky JM. Synthesis of an organoinsulin molecule that can be activated by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 98: 13514-8. PMID 11707596 DOI: 10.1073/Pnas.241516698  0.478
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