☰

Rebecca T. Ruck, Ph.D. - Publications

Affiliations: 
2003 Harvard University, Cambridge, MA, United States 
Area:
Mechanistic and synthetic chemistry
Tree Info Similar researchers PubMed Report error

17/50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. Acs Organic & Inorganic Au. 3: 321-327. PMID 38075448 DOI: 10.1021/acsorginorgau.3c00050  0.682
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. Acs Central Science. 9: 1846-1852. PMID 37901169 DOI: 10.1021/acscentsci.3c01136  0.682
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. Acs Medicinal Chemistry Letters. 14: 1311-1317. PMID 37849544 DOI: 10.1021/acsmedchemlett.3c00412  0.682
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. Biochemistry. PMID 37772735 DOI: 10.1021/acs.biochem.3c00495  0.682
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. Organic Letters. PMID 37772728 DOI: 10.1021/acs.orglett.3c03103  0.682
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. Journal of Medicinal Chemistry. PMID 37772719 DOI: 10.1021/acs.jmedchem.3c01704  0.682
2023 Cantor EH, Faul MM, Huryn DM, Kallander L, Ruck RT, Watson MP. Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. The Journal of Organic Chemistry. PMID 37772717 DOI: 10.1021/acs.joc.3c02082  0.682
2018 Metsänen TT, Lexa KW, Santiago CB, Chung CK, Xu Y, Liu Z, Humphrey GR, Ruck RT, Sherer EC, Sigman MS. Combining traditional 2D and modern physical organic-derived descriptors to predict enhanced enantioselectivity for the key aza-Michael conjugate addition in the synthesis of Prevymis™ (letermovir). Chemical Science. 9: 6922-6927. PMID 30210766 DOI: 10.1039/C8Sc02089B  0.495
2017 Ji Y, Li H, Hyde AM, Chen Q, Belyk KM, Lexa KW, Yin J, Sherer EC, Williamson RT, Brunskill A, Ren S, Campeau LC, Davies IW, Ruck RT. A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions. Chemical Science. 8: 2841-2851. PMID 28553522 DOI: 10.1039/C6Sc05472B  0.438
2017 Ashley ER, Sherer EC, Pio B, Orr RK, Ruck RT. Ruthenium-Catalyzed Dynamic Kinetic Resolution Asymmetric Transfer Hydrogenation of β-Chromanones by an Elimination-Induced Racemization Mechanism Acs Catalysis. 7: 1446-1451. DOI: 10.1021/Acscatal.6B03191  0.647
2013 Bassan E, Ruck RT, Dienemann E, Emerson KM, Humphrey GR, Raheem IT, Tschaen DM, Vickery TP, Wood HB, Yasuda N. Merck's Reaction Review Policy: An Exercise in Process Safety Organic Process Research and Development. 17: 1611-1616. DOI: 10.1021/op4002033  0.603
2005 Blum SA, Rivera VA, Ruck RT, Michael FE, Bergman RG. Synthetic and Mechanistic Studies of Strained Heterocycle Opening Reactions Mediated by Zirconium(IV) Imido Complexes. Organometallics. 24: 1647-1659. PMID 16508693 DOI: 10.1021/Om049105R  0.391
2004 Ruck RT, Bergman RG. Reactions of Imines with Azazirconacyclobutenes and Generation of Electron-Deficient Imidozirconocene Complexes. Organometallics. 23: 2231-2233. PMID 16508694 DOI: 10.1021/Om0497994  0.35
2004 Ruck RT, Bergman RG. Zirconium-mediated conversion of amides to nitriles: a surprising additive effect. Angewandte Chemie (International Ed. in English). 43: 5375-7. PMID 15468091 DOI: 10.1002/Anie.200461064  0.42
2004 Ruck RT, Zuckerman RL, Krska SW, Bergman RG. Carboamination: additions of imine C=N bonds across alkynes catalyzed by imidozirconium complexes. Angewandte Chemie (International Ed. in English). 43: 5372-4. PMID 15468090 DOI: 10.1002/Anie.200461063  0.403
2003 Ruck RT, Jacobsen EN. Asymmetric hetero-ene reactions of trimethylsilyl enol ethers catalyzed by tridentate Schiff base chromium(III) complexes. Angewandte Chemie (International Ed. in English). 42: 4771-4. PMID 14562344 DOI: 10.1002/Anie.200351591  0.516
2002 Ruck RT, Jacobsen EN. Asymmetric catalysis of hetero-ene reactions with tridentate Schiff base chromium(III) complexes. Journal of the American Chemical Society. 124: 2882-3. PMID 11902873 DOI: 10.1021/Ja025588J  0.503
Low-probability matches (unlikely to be authored by this person)
2020 Ruck RT. Eric Jacobsen and Gender Diversity in Organic Chemistry Advanced Synthesis & Catalysis. 362: 285-286. DOI: 10.1002/ADSC.201901110  0.275
2017 Chung CK, Liu Z, Lexa K, Andreani T, Xu Y, Ji Y, DiRocco DA, Humphrey GR, Ruck RT. Asymmetric Hydrogen Bonding Catalysis for the Synthesis of Dihydroquinazoline-containing Antiviral, Letermovir. Journal of the American Chemical Society. PMID 28737937 DOI: 10.1021/Jacs.7B05806  0.231
2018 Friedfeld MR, Zhong H, Ruck RT, Shevlin M, Chirik PJ. Cobalt-catalyzed asymmetric hydrogenation of enamides enabled by single-electron reduction. Science (New York, N.Y.). 360: 888-893. PMID 29798879 DOI: 10.1126/Science.Aar6117  0.206
2019 Vanable EP, Kennemur JL, Joyce LA, Ruck RT, Schultz DM, Hull KL. Rhodium-Catalyzed Asymmetric Hydroamination of Allyl Amines. Journal of the American Chemical Society. PMID 30614700 DOI: 10.1021/Jacs.8B09811  0.201
2019 Daponte JA, Guo Y, Ruck RT, Hein JE. Using an Automated Monitoring Platform for Investigations of Biphasic Reactions Acs Catalysis. 9: 11484-11491. DOI: 10.1021/Acscatal.9B03953  0.199
2008 Ruck RT, Huffman MA, Kim MM, Shevlin M, Kandur WV, Davies IW. ChemInform Abstract: Palladium-Catalyzed Tandem Heck Reaction/C-H Functionalization - Preparation of Spiro-Indan Oxindoles. Cheminform. 39. DOI: 10.1002/CHIN.200841027  0.188
2017 DiRocco DA, Ji Y, Sherer EC, Klapars A, Reibarkh M, Dropinski J, Mathew R, Maligres P, Hyde AM, Limanto J, Brunskill A, Ruck RT, Campeau LC, Davies IW. A multifunctional catalyst that stereoselectively assembles prodrugs. Science (New York, N.Y.). 356: 426-430. PMID 28450641 DOI: 10.1126/Science.Aam7936  0.188
2021 Klapars A, Chung JYL, Limanto J, Calabria R, Campeau LC, Campos KR, Chen W, Dalby SM, Davis TA, DiRocco DA, Hyde AM, Kassim AM, Larsen MU, Liu G, Maligres PE, ... ... Ruck RT, et al. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods. Chemical Science. 12: 9031-9036. PMID 34276931 DOI: 10.1039/d1sc01978c  0.181
2021 Klapars A, Chung JYL, Limanto J, Calabria R, Campeau LC, Campos KR, Chen W, Dalby SM, Davis TA, DiRocco DA, Hyde AM, Kassim AM, Larsen MU, Liu G, Maligres PE, ... ... Ruck RT, et al. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods. Chemical Science. 12: 9031-9036. PMID 34276931 DOI: 10.1039/d1sc01978c  0.181
2008 Ruck RT, Huffman MA, Kim MM, Shevlin M, Kandur WV, Davies IW. Palladium-catalyzed tandem Heck reaction/C-H functionalization--preparation of spiro-indane-oxindoles. Angewandte Chemie (International Ed. in English). 47: 4711-4. PMID 18491340 DOI: 10.1002/anie.200800549  0.181
2016 Basu K, Poirier M, Ruck RT. Solution to the C3-Arylation of Indazoles: Development of a Scalable Method. Organic Letters. PMID 27336404 DOI: 10.1021/acs.orglett.6b01456  0.179
2012 Bellomo A, Celebi-Olcum N, Bu X, Rivera N, Ruck RT, Welch CJ, Houk KN, Dreher SD. Rapid catalyst identification for the synthesis of the pyrimidinone core of HIV integrase inhibitors. Angewandte Chemie (International Ed. in English). 51: 6912-5. PMID 22689502 DOI: 10.1002/Anie.201201720  0.171
2022 McIntosh JA, Liu Z, Andresen BM, Marzijarani NS, Moore JC, Marshall NM, Borra-Garske M, Obligacion JV, Fier PS, Peng F, Forstater JH, Winston MS, An C, Chang W, Lim J, ... ... Ruck RT, et al. A kinase-cGAS cascade to synthesize a therapeutic STING activator. Nature. 603: 439-444. PMID 35296845 DOI: 10.1038/s41586-022-04422-9  0.133
2016 Christensen M, Nolting A, Shevlin M, Weisel M, Maligres PE, Lee J, Orr RK, Plummer CW, Tudge MT, Campeau LC, Ruck RT. Enantioselective Synthesis of α-Methyl-β-Cyclopropyldihydrocinnamates. The Journal of Organic Chemistry. PMID 26743694 DOI: 10.1021/acs.joc.5b02296  0.132
1998 Ruck RT, Jones M. Solvent perturbs the reactivity of tert-butylcarbene Tetrahedron Letters. 39: 2277-2280. DOI: 10.1016/S0040-4039(98)00291-3  0.132
2019 Ruck RT, Faul MM. Gender Diversity in Process Chemistry Organic Process Research & Development. 23: 109-113. DOI: 10.1021/ACS.OPRD.8B00378  0.121
2018 Twilton J, Christensen M, DiRocco DA, Ruck RT, Davies IW, MacMillan DW. Selective Hydrogen Atom Abstraction via Induced Bond Polarization: The Direct -Arylation of Alcohols via Photoredox, HAT and Nickel Catalysis. Angewandte Chemie (International Ed. in English). PMID 29490112 DOI: 10.1002/Anie.201800749  0.117
2018 Orr RK, McCabe Dunn JM, Nolting A, Hyde AM, Ashley ER, Leone J, Sirota E, Jurica JA, Gibson A, Wise C, Oliver S, Ruck RT. New reactions and processes for the efficient synthesis of a HCV NS5b prodrug Green Chemistry. 20: 2519-2525. DOI: 10.1039/C8GC00102B  0.116
2017 Xu F, Zhong YL, Li H, Qi J, Desmond R, Song ZJ, Park J, Wang T, Truppo M, Humphrey GR, Ruck RT. Asymmetric Synthesis of Functionalized trans-Cyclopropoxy Building Block for Grazoprevir. Organic Letters. PMID 29052413 DOI: 10.1021/acs.orglett.7b02867  0.115
2017 McCabe Dunn JM, Reibarkh M, Sherer EC, Orr RK, Ruck RT, Simmons B, Bellomo A. The protecting-group free selective 3'-functionalization of nucleosides. Chemical Science. 8: 2804-2810. PMID 28553517 DOI: 10.1039/C6Sc05081F  0.11
2016 Orr R, Campeau L, Chobanian H, McCabe Dunn J, Pio B, Plummer C, Nolting A, Ruck R. A Modular Synthesis of 2-Alkyl- and 2-Arylchromans via a Three-Step Sequence Synthesis. 49: 657-666. DOI: 10.1055/s-0036-1588075  0.099
2011 Mangion IK, Ruck RT, Rivera N, Huffman MA, Shevlin M. A concise synthesis of a β-lactamase inhibitor. Organic Letters. 13: 5480-3. PMID 21916523 DOI: 10.1021/ol202195n  0.094
2016 Chung CK, Cleator E, Dumas AM, Hicks JD, Humphrey GR, Maligres PE, Nolting AF, Rivera N, Ruck RT, Shevlin M. A Synthesis of a Spirocyclic Macrocyclic Protease Inhibitor for the Treatment of Hepatitis C. Organic Letters. PMID 26950496 DOI: 10.1021/acs.orglett.6b00331  0.09
2008 Kim MM, Ruck RT, Zhao D, Huffman MA. Green iodination of pyrazoles with iodine/hydrogen peroxide in water Tetrahedron Letters. 49: 4026-4028. DOI: 10.1016/j.tetlet.2008.04.082  0.088
2016 Neelamkavil SF, Agrawal S, Bara T, Bennett C, Bhat S, Biswas D, Brockunier L, Buist N, Burnette D, Cartwright M, Chackalamannil S, Chase R, Chelliah M, Chen A, Clasby M, ... ... Ruck RT, et al. Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor. Acs Medicinal Chemistry Letters. 7: 111-6. PMID 26819676 DOI: 10.1021/Acsmedchemlett.5B00425  0.068
2017 Boga SB, Christensen M, Perrotto N, Krska SW, Dreher S, Tudge MT, Ashley ER, Poirier M, Reibarkh M, Liu Y, Streckfuss E, Campeau L, Ruck RT, Davies IW, Vachal P. Selective functionalization of complex heterocycles via an automated strong base screening platform Reaction Chemistry & Engineering. 2: 446-450. DOI: 10.1039/C7Re00057J  0.06
2020 Ren H, Maloney KM, Basu K, Di Maso MJ, Humphrey G, Peng F, Desmond R, Otte DAL, Alwdi E, Liu W, Zhang SW, Song S, Arvary RA, Zompa MA, Lehnherr D, ... ... Ruck RT, et al. Development of a Green & Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview Org. Process Res. Dev.. DOI: 10.1021/acs.oprd.0c00248  0.053
2018 Yu W, Tong L, Selyutin O, Chen L, Hu B, Zhong B, Hao J, Ji T, Zan S, Yin J, Ruck RT, Curry S, McMonagle P, Agrawal S, Rokosz L, et al. The Discovery of MK-6169, A Potent Pan-genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity Against Common Resistance-Associated Substitutions. Journal of Medicinal Chemistry. PMID 29681153 DOI: 10.1021/Acs.Jmedchem.7B01927  0.052
1998 Ruck RT, Jones M. Bicyclo[2.2.1]heptan-1-ylcarbene can ring expand Tetrahedron Letters. 39: 4433-4436. DOI: 10.1016/S0040-4039(98)00840-5  0.04
2016 Tong L, Yu W, Coburn CA, Chen L, Selyutin O, Zeng Q, Dwyer MP, Nair AG, Shankar BB, Kim SH, Yang DY, Rosenblum SB, Ruck RT, Davies IW, Hu B, et al. Structure-activity relationships of proline modifications around the tetracyclic-indole class of NS5A inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27680588 DOI: 10.1016/j.bmcl.2016.08.097  0.038
2016 Tong L, Yu W, Chen L, Selyutin O, Dwyer MP, Nair AG, Mazzola R, Kim JH, Sha D, Yin J, Ruck RT, Davies IW, Hu B, Zhong B, Hao J, et al. The Discovery of Ruzasvir (MK-8408): A Potent, Pan-genotype HCV NS5A Inhibitor with Optimized Activity Against Common Resistance-Associated Polymorphisms. Journal of Medicinal Chemistry. PMID 27808515 DOI: 10.1021/Acs.Jmedchem.6B01310  0.035
2012 He S, Ye Z, Truong Q, Shah S, Du W, Guo L, Dobbelaar PH, Lai Z, Liu J, Jian T, Qi H, Bakshi RK, Hong Q, Dellureficio J, Pasternak A, ... ... Ruck RT, et al. The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes. Acs Medicinal Chemistry Letters. 3: 484-9. PMID 24900499 DOI: 10.1021/ml300063m  0.028
2012 Ruck RT, Huffman MA, Stewart GW, Cleator E, Kandur WV, Kim MM, Zhao D. Route development and multikilogram GMP delivery of a somatostatin receptor antagonist Organic Process Research and Development. 16: 1329-1337. DOI: 10.1021/op300128c  0.015
Hide low-probability matches.