Ranepuradewage E. Chandrasena, Ph.D. - Publications

Affiliations: 
2006 University of Illinois at Chicago, Chicago, IL, United States 
Area:
radical chemistry

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Hemachandra LP, Patel H, Chandrasena RE, Choi J, Piyankarage SC, Wang S, Wang Y, Thayer EN, Scism RA, Michalsen BT, Xiong R, Siklos MI, Bolton JL, Thatcher GR. SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites. Cancer Prevention Research (Philadelphia, Pa.). 7: 505-15. PMID 24598415 DOI: 10.1158/1940-6207.Capr-13-0296  0.44
2012 Michalsen BT, Gherezghiher TB, Choi J, Chandrasena RE, Qin Z, Thatcher GR, Bolton JL. Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiol. Chemical Research in Toxicology. 25: 1472-83. PMID 22642258 DOI: 10.1021/Tx300142H  0.44
2012 Gherezghiher TB, Michalsen B, Chandrasena RE, Qin Z, Sohn J, Thatcher GR, Bolton JL. The naphthol selective estrogen receptor modulator (SERM), LY2066948, is oxidized to an o-quinone analogous to the naphthol equine estrogen, equilenin. Chemico-Biological Interactions. 196: 1-10. PMID 22290292 DOI: 10.1016/J.Cbi.2012.01.004  0.44
2011 Abdul-Hay S, Schiefer IT, Chandrasena RE, Li M, Abdelhamid R, Wang YT, Tavassoli E, Michalsen B, Asghodom RT, Luo J, Thatcher GR. NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor. Acs Medicinal Chemistry Letters. 2: 656-661. PMID 21927645 DOI: 10.1021/Ml2000033  0.44
2010 Sinha V, Wijewickrama GT, Chandrasena RE, Xu H, Edirisinghe PD, Schiefer IT, Thatcher GR. Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors. Acs Chemical Biology. 5: 667-80. PMID 20524644 DOI: 10.1021/Cb100054M  0.44
2010 Kim HY, Sohn J, Wijewickrama GT, Edirisinghe P, Gherezghiher T, Hemachandra M, Lu PY, Chandrasena RE, Molloy ME, Tonetti DA, Thatcher GR. Click synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogens. Bioorganic & Medicinal Chemistry. 18: 809-21. PMID 20031420 DOI: 10.1016/J.Bmc.2009.11.046  0.44
2008 Hagos GK, Abdul-Hay SO, Sohn J, Edirisinghe PD, Chandrasena RE, Wang Z, Li Q, Thatcher GR. Anti-inflammatory, antiproliferative, and cytoprotective activity of NO chimera nitrates of use in cancer chemoprevention. Molecular Pharmacology. 74: 1381-91. PMID 18676677 DOI: 10.1124/Mol.108.046664  0.44
2008 Chandrasena RE, Edirisinghe PD, Bolton JL, Thatcher GR. Problematic detoxification of estrogen quinones by NAD(P)H-dependent quinone oxidoreductase and glutathione-S-transferase. Chemical Research in Toxicology. 21: 1324-9. PMID 18588320 DOI: 10.1021/Tx8000797  0.44
2008 Dunlap T, Abdul-Hay SO, Chandrasena RE, Hagos GK, Sinha V, Wang Z, Wang H, Thatcher GR. Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 19: 115-24. PMID 18485921 DOI: 10.1016/J.Niox.2008.04.013  0.44
2007 Dunlap T, Chandrasena RE, Wang Z, Sinha V, Wang Z, Thatcher GR. Quinone formation as a chemoprevention strategy for hybrid drugs: balancing cytotoxicity and cytoprotection. Chemical Research in Toxicology. 20: 1903-12. PMID 17975886 DOI: 10.1021/Tx7002257  0.44
2007 Qin Z, Kastrati I, Chandrasena RE, Liu H, Yao P, Petukhov PA, Bolton JL, Thatcher GR. Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity. Journal of Medicinal Chemistry. 50: 2682-92. PMID 17489582 DOI: 10.1021/Jm070079J  0.44
2007 Newcomb M, Lansakara-P DS, Kim HY, Chandrasena RE, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ. Products from enzyme-catalyzed oxidations of norcarenes. The Journal of Organic Chemistry. 72: 1128-33. PMID 17288367 DOI: 10.1021/Jo061865J  0.44
2007 Newcomb M, Chandrasena RE, Lansakara-P DS, Kim HY, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ. Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane. The Journal of Organic Chemistry. 72: 1121-7. PMID 17288366 DOI: 10.1021/Jo061864R  0.44
2006 Newcomb M, Zhang R, Chandrasena RE, Halgrimson JA, Horner JH, Makris TM, Sligar SG. Cytochrome p450 compound I. Journal of the American Chemical Society. 128: 4580-1. PMID 16594688 DOI: 10.1021/Ja060048Y  0.44
2006 Newcomb M, Zhang R, Pan Z, Harischandra DN, Chandrasena REP, Horner JH, Martinez E. Laser flash photolysis production of metal-oxo derivatives and direct kinetic studies of their oxidation reactions Catalysis Today. 117: 98-104. DOI: 10.1016/J.Cattod.2006.05.007  0.6
2005 Newcomb M, Chandrasena RE. Highly reactive electrophilic oxidants in cytochrome P450 catalysis. Biochemical and Biophysical Research Communications. 338: 394-403. PMID 16168951 DOI: 10.1016/J.Bbrc.2005.08.208  0.44
2005 Zhang R, Chandrasena RE, Martinez E, Horner JH, Newcomb M. Formation of compound I by photo-oxidation of compound II. Organic Letters. 7: 1193-5. PMID 15760172 DOI: 10.1021/Ol050296J  0.6
2004 Chandrasena RE, Vatsis KP, Coon MJ, Hollenberg PF, Newcomb M. Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes. Journal of the American Chemical Society. 126: 115-26. PMID 14709076 DOI: 10.1021/Ja038237T  0.44
2003 Newcomb M, Aebisher D, Shen R, Chandrasena RE, Hollenberg PF, Coon MJ. Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations. Journal of the American Chemical Society. 125: 6064-5. PMID 12785830 DOI: 10.1021/Ja0343858  0.44
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