Year |
Citation |
Score |
2018 |
Nagiec MM, Duvall JR, Skepner AP, Howe EA, Bastien J, Comer E, Marie JC, Johnston SE, Negri J, Eichhorn M, Vantourout J, Clish C, Musunuru K, Foley M, Perez JR, et al. Novel tricyclic glycal-based inducers that reprogram LDL metabolism in hepatic cells. Medchemcomm. 9: 1831-1842. PMID 30542533 DOI: 10.1039/C8Md00297E |
0.302 |
|
2017 |
Duvall JR, Bedard L, Naylor-Olsen AM, Manson AL, Bittker JA, Sun W, Fitzgerald ME, He Z, Lee MD, Marie JC, Muncipinto G, Rush D, Xu D, Xu H, Zhang M, et al. Identification of highly specific diversity-oriented synthesis-derived inhibitors of Clostridium difficile. Acs Infectious Diseases. PMID 28215073 DOI: 10.1021/Acsinfecdis.6B00206 |
0.391 |
|
2016 |
Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan G, Duffy S, Eckley S, ... ... Duvall JR, et al. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. Nature. PMID 27602946 DOI: 10.1038/Nature19804 |
0.403 |
|
2016 |
Duvall JR, VerPlank L, Ludeke B, McLeod SM, Lee MD, Vishwanathan K, Mulrooney CA, Le Quement S, Yu Q, Palmer MA, Fleming P, Fearns R, Foley MA, Scherer CA. Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen. Antiviral Research. PMID 27059228 DOI: 10.1016/J.Antiviral.2016.03.015 |
0.35 |
|
2015 |
Nagiec MM, Skepner AP, Negri J, Eichhorn M, Kuperwasser N, Comer E, Muncipinto G, Subramanian A, Clish C, Musunuru K, Duvall JR, Foley M, Perez JR, Palmer MA. Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression. Plos One. 10: e0120295. PMID 25811180 DOI: 10.1371/Journal.Pone.0120295 |
0.326 |
|
2015 |
Lukens AK, Heidebrecht RW, Mulrooney C, Beaudoin JA, Comer E, Duvall JR, Fitzgerald ME, Masi D, Galinsky K, Scherer CA, Palmer M, Munoz B, Foley M, Schreiber SL, Wiegand RC, et al. Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors. The Journal of Infectious Diseases. 211: 1097-103. PMID 25336726 DOI: 10.1093/Infdis/Jiu565 |
0.364 |
|
2014 |
Comer E, Duvall JR, duPont Lee M. Utilizing diversity-oriented synthesis in antimicrobial drug discovery. Future Medicinal Chemistry. 6: 1927-42. PMID 25495985 DOI: 10.4155/Fmc.14.111 |
0.414 |
|
2014 |
Comer E, Beaudoin JA, Kato N, Fitzgerald ME, Heidebrecht RW, Lee Md, Masi D, Mercier M, Mulrooney C, Muncipinto G, Rowley A, Crespo-Llado K, Serrano AE, Lukens AK, Wiegand RC, ... ... Duvall JR, et al. Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents. Journal of Medicinal Chemistry. 57: 8496-502. PMID 25211597 DOI: 10.1021/Jm500994N |
0.422 |
|
2014 |
Wawer MJ, Li K, Gustafsdottir SM, Ljosa V, Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E, Taylor B, Grant GB, Hon CS, Duvall JR, Wilson JA, et al. Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling. Proceedings of the National Academy of Sciences of the United States of America. 111: 10911-6. PMID 25024206 DOI: 10.1073/Pnas.1410933111 |
0.351 |
|
2014 |
Dandapani S, Germain AR, Jewett I, le Quement S, Marie JC, Muncipinto G, Duvall JR, Carmody LC, Perez JR, Engel JC, Gut J, Kellar D, Siqueira-Neto JL, McKerrow JH, Kaiser M, et al. Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease. Acs Medicinal Chemistry Letters. 5: 149-53. PMID 24900788 DOI: 10.1021/Ml400403U |
0.396 |
|
2014 |
Huo HX, Duvall JR, Huang MY, Hong R. Catalytic asymmetric allylation of carbonyl compounds and imines with allylic boronates Organic Chemistry Frontiers. 1: 303-320. DOI: 10.1039/C3Qo00081H |
0.401 |
|
2013 |
Schaefer GI, Perez JR, Duvall JR, Stanton BZ, Shamji AF, Schreiber SL. Discovery of small-molecule modulators of the Sonic Hedgehog pathway. Journal of the American Chemical Society. 135: 9675-80. PMID 23725514 DOI: 10.1021/Ja400034K |
0.357 |
|
2013 |
Frumm SM, Fan ZP, Ross KN, Duvall JR, Gupta S, VerPlank L, Suh BC, Holson E, Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J, Roti G, Kung AL, et al. Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. Chemistry & Biology. 20: 713-25. PMID 23706636 DOI: 10.1016/J.Chembiol.2013.03.020 |
0.341 |
|
2013 |
Gerard B, Lee MD, Dandapani S, Duvall JR, Fitzgerald ME, Kesavan S, Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M, Hamann D, Lemercier B, Murillo T, et al. Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides. The Journal of Organic Chemistry. 78: 5160-71. PMID 23692141 DOI: 10.1021/Jo4000916 |
0.413 |
|
2013 |
Mulrooney CA, Lahr DL, Quintin MJ, Youngsaye W, Moccia D, Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P, Bittker JA, Clemons PA, Brudz S, Dandapani S, Duvall JR, et al. An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries. Journal of Computer-Aided Molecular Design. 27: 455-68. PMID 23585218 DOI: 10.1007/S10822-013-9641-Y |
0.325 |
|
2012 |
Dandapani S, Comer E, Duvall JR, Munoz B. Hits, leads and drugs against malaria through diversity-oriented synthesis. Future Medicinal Chemistry. 4: 2279-94. PMID 23234551 DOI: 10.4155/Fmc.12.178 |
0.361 |
|
2012 |
Lowe JT, Lee MD, Akella LB, Davoine E, Donckele EJ, Durak L, Duvall JR, Gerard B, Holson EB, Joliton A, Kesavan S, Lemercier BC, Liu H, Marié JC, Mulrooney CA, et al. Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries. The Journal of Organic Chemistry. 77: 7187-211. PMID 22853001 DOI: 10.1021/Jo300974J |
0.403 |
|
2012 |
Heidebrecht RW, Mulrooney C, Austin CP, Barker RH, Beaudoin JA, Cheng KC, Comer E, Dandapani S, Dick J, Duvall JR, Ekland EH, Fidock DA, Fitzgerald ME, Foley M, Guha R, et al. Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria. Acs Medicinal Chemistry Letters. 3: 112-117. PMID 22328964 DOI: 10.1021/Ml200244K |
0.407 |
|
2012 |
Fitzgerald ME, Mulrooney CA, Duvall JR, Wei J, Suh BC, Akella LB, Vrcic A, Marcaurelle LA. Build/couple/pair strategy for the synthesis of stereochemically diverse macrolactams via head-to-tail cyclization. Acs Combinatorial Science. 14: 89-96. PMID 22252910 DOI: 10.1021/Co200161Z |
0.372 |
|
2011 |
Chou DH, Duvall JR, Gerard B, Liu H, Pandya BA, Suh BC, Forbeck EM, Faloon P, Wagner BK, Marcaurelle LA. Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis. Acs Medicinal Chemistry Letters. 2: 698-702. PMID 21927648 DOI: 10.1021/Ml200120M |
0.415 |
|
2011 |
Pandya BA, Dandapani S, Duvall JR, Rowley A, Mulrooney CA, Ryba T, Dombrowski M, Harton M, Young DW, Marcaurelle LA. Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions. Tetrahedron. 67: 6131-6137. PMID 21822337 DOI: 10.1016/J.Tet.2011.06.043 |
0.349 |
|
2011 |
Kuai L, Ong SE, Madison JM, Wang X, Duvall JR, Lewis TA, Luce CJ, Conner SD, Pearlman DA, Wood JL, Schreiber SL, Carr SA, Scolnick EM, Haggarty SJ. AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics. Chemistry & Biology. 18: 891-906. PMID 21802010 DOI: 10.1016/J.Chembiol.2011.03.017 |
0.302 |
|
2011 |
Gerard B, Duvall JR, Lowe JT, Murillo T, Wei J, Akella LB, Marcaurelle LA. Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification. Acs Combinatorial Science. 13: 365-74. PMID 21526820 DOI: 10.1021/Co2000218 |
0.379 |
|
2010 |
Duvall JR, Vrcic A, Marcaurelle LA. Small-Molecule Library Synthesis on Silicon-Functionalized SynPhase Lanterns. Current Protocols in Chemical Biology. 2: 135-151. PMID 22679566 DOI: 10.1002/9780470559277.Ch100038 |
0.418 |
|
2010 |
Marcaurelle LA, Comer E, Dandapani S, Duvall JR, Gerard B, Kesavan S, Lee MD, Liu H, Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A, Ryba TD, Suh BC, et al. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. Journal of the American Chemical Society. 132: 16962-76. PMID 21067169 DOI: 10.1021/Ja105119R |
0.452 |
|
2006 |
Spiegel DA, Schroeder FC, Duvall JR, Schreiber SL. An oligomer-based approach to skeletal diversity in small-molecule synthesis. Journal of the American Chemical Society. 128: 14766-7. PMID 17105261 DOI: 10.1021/Ja065724A |
0.401 |
|
2006 |
Duvall JR, Wu F, Snider BB. Structure reassignment and synthesis of Jenamidines A1/A2, synthesis of (+)-NP25302, and formal synthesis of SB-311009 analogues. The Journal of Organic Chemistry. 71: 8579-90. PMID 17064037 DOI: 10.1021/Jo061650+ |
0.532 |
|
2005 |
Snider BB, Duvall JR. Synthesis of jenamidines A1/A2. Organic Letters. 7: 4519-22. PMID 16178573 DOI: 10.1021/Ol0518784 |
0.499 |
|
2004 |
Snider BB, Duvall JR. Termination of Mn(III)-based oxidative cyclizations by trapping with azide. Organic Letters. 6: 1265-8. PMID 15070313 DOI: 10.1021/Ol049805S |
0.477 |
|
2004 |
Snider BB, Duvall JR, Sattler I, Huang X. Synthesis of a piperidone model compound and revision of the structures of jenamidines A to C Tetrahedron Letters. 45: 6725-6727. DOI: 10.1016/J.Tetlet.2004.07.055 |
0.524 |
|
2003 |
Snider BB, Duvall JR. Synthesis of the 4-methyl-1,2-oxazetidine-4-carboxylic acid moiety of the originally proposed halipeptin A and B structures Tetrahedron Letters. 44: 3067-3070. DOI: 10.1016/S0040-4039(03)00542-2 |
0.491 |
|
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