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Malken Bayrakdarian, Ph.D. - Publications

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
chemistry of natural products
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Cantin LD, Bayrakdarian M, Buon C, Grazzini E, Hu YJ, Labrecque J, Leung C, Luo X, Martino G, Paré M, Payza K, Popovic N, Projean D, Santhakumar V, Walpole C, et al. Discovery of P2X3 selective antagonists for the treatment of chronic pain. Bioorganic & Medicinal Chemistry Letters. 22: 2565-71. PMID 22370269 DOI: 10.1016/j.bmcl.2012.01.124  0.484
2008 Hanessian S, Simard D, Bayrakdarian M, Therrien E, Nilsson I, Fjellström O. Design, synthesis, and thrombin-inhibitory activity of pyridin-2-ones as P2/P3 core motifs. Bioorganic & Medicinal Chemistry Letters. 18: 1972-6. PMID 18289852 DOI: 10.1016/J.Bmcl.2008.01.122  0.512
2006 Hanessian S, Therrien E, van Otterlo WA, Bayrakdarian M, Nilsson I, Fjellström O, Xue Y. Phenolic P2/P3 core motif as thrombin inhibitors--design, synthesis, and X-ray co-crystal structure. Bioorganic & Medicinal Chemistry Letters. 16: 1032-6. PMID 16290930 DOI: 10.1016/J.Bmcl.2005.10.082  0.49
2005 Hanessian S, Hou Y, Bayrakdarian M, Tintelnot-Blomley M. Stereoselective synthesis of constrained oxacyclic hydroxyethylene isosteres of aspartic protease inhibitors: aldol and Mukaiyama aldol methodologies for branched tetrahydrofuran 2-carboxylic acids. The Journal of Organic Chemistry. 70: 6735-45. PMID 16095293 DOI: 10.1021/Jo050749Y  0.501
2005 Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, et al. Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. Journal of Medicinal Chemistry. 48: 5175-90. PMID 16078837 DOI: 10.1021/Jm050142+  0.524
2002 Hanessian S, Buckle R, Bayrakdarian M. Design and synthesis of a novel class of constrained tricyclic pyrrolizidinone carboxylic acids as carbapenem mimics. The Journal of Organic Chemistry. 67: 3387-97. PMID 12003550 DOI: 10.1021/Jo0111715  0.509
2002 Hanessian S, Bayrakdarian M, Luo X. Total synthesis of A-315675: a potent inhibitor of influenza neuraminidase. Journal of the American Chemical Society. 124: 4716-21. PMID 11971721 DOI: 10.1021/Ja0126226  0.525
2002 Hanessian S, Bayrakdarian M. Solution- and solid-phase asymmetric synthesis of substituted N-hydroxypyrrolidine dicarboxylic acids Tetrahedron Letters. 43: 9441-9444. DOI: 10.1016/S0040-4039(02)02288-8  0.503
2002 Hanessian S, Bayrakdarian M. Asymmetric synthesis of diversely substituted N-hydroxypyrrolidines using cycloadditions with chiral nitrone enolate/ylids Tetrahedron Letters. 43: 967-971. DOI: 10.1016/S0040-4039(01)02305-X  0.497
2000 Hanessian S, Bayrakdarian M. Pyrrolidine as a cogwheel-like scaffold for the deployment of diverse functionality through cycloaddition reactions of metallo-1,3-dipoles in aqueous media. Bioorganic & Medicinal Chemistry Letters. 10: 427-31. PMID 10743941 DOI: 10.1016/S0960-894X(00)00020-2  0.425
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