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Tania J. Lupoli, Ph.D. - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
molecular mechanisms of various antibiotics
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Harnagel AP, Sheshova M, Zheng M, Zheng M, Skorupinska-Tudek K, Swiezewska E, Lupoli TJ. Preference of Bacterial Rhamnosyltransferases for 6-Deoxysugars Reveals a Strategy To Deplete O-Antigens. Journal of the American Chemical Society. 145: 15639-15646. PMID 37437030 DOI: 10.1021/jacs.3c03005  0.351
2023 Zheng M, Zheng MC, Kim H, Lupoli TJ. Feedback Inhibition of Bacterial Nucleotidyltransferases by Rare Nucleotide l-Sugars Restricts Substrate Promiscuity. Journal of the American Chemical Society. PMID 37283497 DOI: 10.1021/jacs.3c02319  0.604
2022 Zheng M, Zheng M, Lupoli TJ. Expanding the Substrate Scope of a Bacterial Nucleotidyltransferase via Allosteric Mutations. Acs Infectious Diseases. PMID 36106727 DOI: 10.1021/acsinfecdis.2c00402  0.597
2022 Nelson B, Hong SH, Lupoli TJ. Protein Cofactor Mimics Disrupt Essential Chaperone Function in Stressed Mycobacteria. Acs Infectious Diseases. 8: 901-910. PMID 35412813 DOI: 10.1021/acsinfecdis.1c00651  0.305
2021 Hosfelt J, Richards A, Zheng M, Adura C, Nelson B, Yang A, Fay A, Resager W, Ueberheide B, Glickman JF, Lupoli TJ. An allosteric inhibitor of bacterial Hsp70 chaperone potentiates antibiotics and mitigates resistance. Cell Chemical Biology. PMID 34818532 DOI: 10.1016/j.chembiol.2021.11.004  0.589
2021 Zheng M, Zheng M, Epstein S, Harnagel AP, Kim H, Lupoli TJ. Chemical Biology Tools for Modulating and Visualizing Gram-Negative Bacterial Surface Polysaccharides. Acs Chemical Biology. PMID 34569792 DOI: 10.1021/acschembio.1c00341  0.555
2021 Zheng M, Lupoli TJ. Modulation of a Mycobacterial ADP-Ribosyltransferase to Augment Rifamycin Antibiotic Resistance. Acs Infectious Diseases. PMID 34355905 DOI: 10.1021/acsinfecdis.1c00297  0.567
2020 Lopez Quezada L, Smith R, Lupoli TJ, Edoo Z, Li X, Gold B, Roberts J, Ling Y, Park SW, Nguyen Q, Schoenen FJ, Li K, Hugonnet JE, Arthur M, Sacchettini JC, et al. Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases. Frontiers in Microbiology. 11: 1248. PMID 32655524 DOI: 10.3389/Fmicb.2020.01248  0.363
2018 Yu H, Lupoli TJ, Kovach A, Meng X, Zhao G, Nathan CF, Li H. ATP hydrolysis-coupled peptide translocation mechanism of ClpB. Proceedings of the National Academy of Sciences of the United States of America. PMID 30257943 DOI: 10.1073/Pnas.1810648115  0.351
2016 Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan CF. Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872278 DOI: 10.1073/Pnas.1617644113  0.381
2016 Markovski M, Bohrhunter JL, Lupoli TJ, Uehara T, Walker S, Kahne DE, Bernhardt TG. Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071112 DOI: 10.1073/Pnas.1524538113  0.621
2014 Lebar MD, May JM, Meeske AJ, Leiman SA, Lupoli TJ, Tsukamoto H, Losick R, Rudner DZ, Walker S, Kahne D. Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis. Journal of the American Chemical Society. 136: 10874-7. PMID 25036369 DOI: 10.1021/Ja505668F  0.737
2014 Lupoli TJ, Lebar MD, Markovski M, Bernhardt T, Kahne D, Walker S. Lipoprotein activators stimulate escherichia coli penicillin-binding proteins by different mechanisms Journal of the American Chemical Society. 136: 52-55. PMID 24341982 DOI: 10.1021/Ja410813J  0.72
2014 Rebets Y, Lupoli T, Qiao Y, Schirner K, Villet R, Hooper D, Kahne D, Walker S. Moenomycin resistance mutations in Staphylococcus aureus reduce peptidoglycan chain length and cause aberrant cell division. Acs Chemical Biology. 9: 459-67. PMID 24255971 DOI: 10.1021/Cb4006744  0.588
2014 Lebar MD, May JM, Meeske AJ, Leiman SA, Lupoli TJ, Tsukamoto H, Losick R, Rudner DZ, Walker S, Kahne D. Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis Journal of the American Chemical Society. 136: 10874-10877. DOI: 10.1021/ja505668f  0.69
2013 Lebar MD, Lupoli TJ, Tsukamoto H, May JM, Walker S, Kahne D. Forming cross-linked peptidoglycan from synthetic gram-negative lipid II Journal of the American Chemical Society. 135: 4632-4635. PMID 23480167 DOI: 10.1021/Ja312510M  0.744
2012 Knerr PJ, Oman TJ, Garcia De Gonzalo CV, Lupoli TJ, Walker S, Van Der Donk WA. Non-proteinogenic amino acids in lacticin 481 analogues result in more potent inhibition of peptidoglycan transglycosylation Acs Chemical Biology. 7: 1791-1795. PMID 22920239 DOI: 10.1021/Cb300372B  0.438
2011 Oman TJ, Lupoli TJ, Wang TSA, Kahne D, Walker S, Van Der Donk WA. Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry Journal of the American Chemical Society. 133: 17544-17547. PMID 22003874 DOI: 10.1021/Ja206281K  0.685
2011 Lupoli TJ, Tsukamoto H, Doud EH, Wang TS, Walker S, Kahne D. Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. Journal of the American Chemical Society. 133: 10748-51. PMID 21682301 DOI: 10.1021/Ja2040656  0.755
2011 Wang TS, Lupoli TJ, Sumida Y, Tsukamoto H, Wu Y, Rebets Y, Kahne DE, Walker S. Primer preactivation of peptidoglycan polymerases. Journal of the American Chemical Society. 133: 8528-30. PMID 21568328 DOI: 10.1021/Ja2028712  0.738
2010 Paradis-Bleau C, Markovski M, Uehara T, Lupoli TJ, Walker S, Kahne DE, Bernhardt TG. Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases. Cell. 143: 1110-20. PMID 21183074 DOI: 10.1016/J.Cell.2010.11.037  0.652
2009 Lupoli TJ, Taniguchi T, Wang TS, Perlstein DL, Walker S, Kahne DE. Studying a cell division amidase using defined peptidoglycan substrates. Journal of the American Chemical Society. 131: 18230-1. PMID 19957935 DOI: 10.1021/Ja908916Z  0.701
2007 Leimkuhler C, Fridman M, Lupoli T, Walker S, Walsh CT, Kahne D. Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A. Journal of the American Chemical Society. 129: 10546-50. PMID 17685523 DOI: 10.1021/Ja072909O  0.698
2007 Fridman M, Balibar CJ, Lupoli T, Kahne D, Walsh CT, Garneau-Tsodikova S. Chemoenzymatic formation of novel aminocoumarin antibiotics by the enzymes CouN1 and CouN7. Biochemistry. 46: 8462-71. PMID 17580964 DOI: 10.1021/Bi700433V  0.606
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