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Jennifer E. Davoren, Ph.D. - Publications

Affiliations: 
2006 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Natural Product Synthesis
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Davoren JE, Garnsey M, Pettersen B, Brodney MA, Edgerton JR, Fortin JP, Grimwood S, Harris AR, Jenkinson S, Kenakin TP, Lazzaro JT, Lee CW, Lotarski SM, Nottebaum L, O'Neil SV, et al. Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity. Journal of Medicinal Chemistry. PMID 28598634 DOI: 10.1021/Acs.Jmedchem.7B00597  0.353
2016 Popiolek M, Nguyen DP, Reinhart V, Edgerton JR, Harms J, Lotarski SM, Steyn SJ, Davoren JE, Grimwood S. Inositol Phosphate Accumulation in Vivo Provides a Measure of Muscarinic M1 Receptor Activation. Biochemistry. PMID 27958713 DOI: 10.1021/Acs.Biochem.6B00688  0.325
2016 Davoren JE, Lee CW, Garnsey M, Brodney MA, Cordes J, Dlugolenski K, Edgerton JR, Harris AR, Helal CJ, Jenkinson S, Kauffman GW, Kenakin T, Lazzaro JT, Lotarski SM, Mao Y, et al. Discovery of the potent and selective M1 PAM-agonist N-[(3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of efficacy and cholinergic side effects. Journal of Medicinal Chemistry. PMID 27275946 DOI: 10.1021/Acs.Jmedchem.6B00544  0.338
2015 Davoren JE, O'Neil SV, Anderson DP, Brodney MA, Chenard L, Dlugolenski K, Edgerton JR, Green M, Garnsey M, Grimwood S, Harris AR, Kauffman GW, LaChapelle E, Lazzaro JT, Lee CW, et al. Design and optimization of selective azaindole amide M1 positive allosteric modulators. Bioorganic & Medicinal Chemistry Letters. PMID 26631313 DOI: 10.1016/J.Bmcl.2015.11.053  0.347
2011 Wang Z, Chi Y, Harris AR, Gray D, Davoren JE. Scalable synthesis of 4-substituted 5-bromo-6-methylpyrimidines Synthesis. 1529-1531. DOI: 10.1055/S-0030-1259976  0.332
2011 Harris AR, Nason DM, Collantes EM, Xu W, Chi Y, Wang Z, Zhang B, Zhang Q, Gray DL, Davoren JE. Synthesis of 5-bromo-6-methyl imidazopyrazine, 5-bromo and 5-chloro-6-methyl imidazopyridine using electron density surface maps to guide synthetic strategy Tetrahedron. 67: 9063-9066. DOI: 10.1016/J.Tet.2011.08.090  0.302
2010 Davoren JE, Gray DL, Harris AR, Nason DM, Xu W. Remarkable [3+2] Annulations of Electron-Rich Olefins with Unstabilized Azomethine Ylides Synlett. 2490-2492. DOI: 10.1055/S-0030-1258026  0.314
2008 Davoren JE, Harcken C, Martin SF. Studies toward the enantioselective syntheses of oxylipins: total synthesis and structure revision of solandelactone E. The Journal of Organic Chemistry. 73: 391-402. PMID 18088137 DOI: 10.1021/Jo701739V  0.46
2007 Davoren JE, Martin SF. Enantioselective synthesis and structure revision of solandelactone E. Journal of the American Chemical Society. 129: 510-1. PMID 17227012 DOI: 10.1021/Ja068270Q  0.457
2001 Liras S, Davoren JE, Bordner J. An approach to the skeleton of the securinega alkaloids. The total synthesis of (+/-)-securinine. Organic Letters. 3: 703-6. PMID 11259041 DOI: 10.1021/Ol0070482  0.368
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