Jack D. Sadowsky, Ph.D. - Publications

2006 University of Wisconsin, Madison, Madison, WI 
biologically active polymers

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA. A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proceedings of the National Academy of Sciences of the United States of America. 111: 18590-5. PMID 25518860 DOI: 10.1073/Pnas.1415365112  0.6
2013 Wang N, Majmudar CY, Pomerantz WC, Gagnon JK, Sadowsky JD, Meagher JL, Johnson TK, Stuckey JA, Brooks CL, Wells JA, Mapp AK. Ordering a dynamic protein via a small-molecule stabilizer. Journal of the American Chemical Society. 135: 3363-6. PMID 23384013 DOI: 10.1021/Ja3122334  0.6
2011 Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proceedings of the National Academy of Sciences of the United States of America. 108: 6056-61. PMID 21430264 DOI: 10.1073/Pnas.1102376108  0.6
2009 Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, Gellman SH, Fairlie WD. High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. Angewandte Chemie (International Ed. in English). 48: 4318-22. PMID 19229915 DOI: 10.1002/Anie.200805761  0.6
2008 Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain. Protein Science : a Publication of the Protein Society. 17: 1232-40. PMID 18467496 DOI: 10.1110/Ps.032896.107  0.6
2008 Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, Bresnick EH, Sheibani N, Gellman SH. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor Analytical Biochemistry. 378: 8-14. PMID 18413228 DOI: 10.1016/J.Ab.2008.03.043  0.6
2008 Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 10: 204-15. PMID 18275161 DOI: 10.1021/Cc700153Z  0.6
2007 Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, Fitzgerald MC. H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. Analytical Chemistry. 79: 5869-77. PMID 17580981 DOI: 10.1021/Ac0700777  0.6
2007 Sadowsky JD, Murray JK, Tomita Y, Gellman SH. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL. Chembiochem : a European Journal of Chemical Biology. 8: 903-16. PMID 17503422 DOI: 10.1002/Cbic.200600546  0.6
2007 Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH. (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. Journal of the American Chemical Society. 129: 139-54. PMID 17199293 DOI: 10.1021/Ja0662523  0.6
2005 Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen J, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 127: 13271-80. PMID 16173757 DOI: 10.1021/Ja052733V  0.6
2005 Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. Journal of the American Chemical Society. 127: 11966-8. PMID 16117535 DOI: 10.1021/Ja053678T  0.6
2001 Blackwell HE, Sadowsky JD, Howard RJ, Sampson JN, Chao JA, Steinmetz WE, O'Leary DJ, Grubbs RH. Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides. The Journal of Organic Chemistry. 66: 5291-302. PMID 11485448 DOI: 10.1021/Jo015533K  0.6
2001 Steinmetz WE, Sadowsky JD, Rice JS, Roberts JJ, Bui YK. Determination of the aqueous-phase structure of 6-O-methylerythromycin from NMR constraints Magnetic Resonance in Chemistry. 39: 163-172. DOI: 10.1002/Mrc.826  0.6
2000 Tung JC, Gonzales AJ, Sadowsky JD, O'Leary DJ. On the 1H NMR chemical shift assignments for ampicillin Magnetic Resonance in Chemistry. 38: 126-128. DOI: 10.1002/(Sici)1097-458X(200002)38:2<126::Aid-Mrc601>3.0.Co;2-W  0.6
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