Brian N. Cook, Ph.D. - Publications

Affiliations: 
2002 University of California, Berkeley, Berkeley, CA 
Area:
Bioorthogonal chemistry

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Cook BN, Bentzien J, White A, Nemoto PA, Wang J, Man CC, Soleymanzadeh F, Khine HH, Kashem MA, Kugler SZ, Wolak JP, Roth GP, De Lombaert S, Pullen SS, Takahashi H. Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design. Bioorganic & Medicinal Chemistry Letters. 19: 773-7. PMID 19111460 DOI: 10.1016/j.bmcl.2008.12.028  1
2009 Moriarty KJ, Takahashi H, Pullen SS, Khine HH, Sallati RH, Raymond EL, Woska JR, Jeanfavre DD, Roth GP, Winters MP, Qiao L, Ryan D, DesJarlais R, Robinson D, Wilson M, ... ... Cook BN, et al. Corrigendum to "Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)" [Bioorg. Med. Chem. Lett. 18 (2008) 5545-5549] (DOI:10.1016/j.bmcl.2008.09.015) Bioorganic and Medicinal Chemistry Letters. 19: 1835. DOI: 10.1016/j.bmcl.2008.09.114  1
2008 Moriarty KJ, Takahashi H, Pullen SS, Khine HH, Sallati RH, Raymond EL, Woska JR, Jeanfavre DD, Roth GP, Winters MP, Qiao L, Ryan D, DesJarlais R, Robinson D, Wilson M, ... ... Cook BN, et al. Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk). Bioorganic & Medicinal Chemistry Letters. 18: 5545-9. PMID 18819799 DOI: 10.1016/j.bmcl.2008.09.015  1
2008 Moriarty KJ, Winters M, Qiao L, Ryan D, DesJarlis R, Robinson D, Cook BN, Kashem MA, Kaplita PV, Liu LH, Farrell TM, Khine HH, King J, Pullen SS, Roth GP, et al. Itk kinase inhibitors: initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead. Bioorganic & Medicinal Chemistry Letters. 18: 5537-40. PMID 18819794 DOI: 10.1016/j.bmcl.2008.09.017  1
2002 Cook BN, Bertozzi CR. Chemical approaches to the investigation of cellular systems. Bioorganic & Medicinal Chemistry. 10: 829-40. PMID 11836089 DOI: 10.1016/S0968-0896(01)00376-5  1
2002 Kehoe JW, Maly DJ, Verdugo DE, Armstrong JI, Cook BN, Ouyang YB, Moore KL, Ellman JA, Bertozzi CR. Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly. Bioorganic & Medicinal Chemistry Letters. 12: 329-32. PMID 11814789 DOI: 10.1016/S0960-894X(01)00744-2  1
2001 Bowman KG, Cook BN, de Graffenried CL, Bertozzi CR. Biosynthesis of L-selectin ligands: sulfation of sialyl Lewis x-related oligosaccharides by a family of GlcNAc-6-sulfotransferases. Biochemistry. 40: 5382-91. PMID 11331001 DOI: 10.1021/Bi001750O  1
2000 Bhakta S, Bartes A, Bowman KG, Kao WM, Polsky I, Lee JK, Cook BN, Bruehl RE, Rosen SD, Bertozzi CR, Hemmerich S. Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5). The Journal of Biological Chemistry. 275: 40226-34. PMID 10956661 DOI: 10.1074/Jbc.M006414200  1
2000 Armstrong JI, Portley AR, Chang YT, Nierengarten DM, Cook BN, Bowman KG, Bishop A, Gray NS, Shokat KM, Schultz PG, Bertozzi CR. Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for numerous helpful conversations. J.I.A. and K.G.B were supported by NIH Molecular Biophysics Training Grant (No. T32GM0895). This research was funded by grants to C.R.B. from the Pew Scholars Program, the W. M. Keck Foundation and the American Cancer Society (Grant No. RPG9700501BE). Angewandte Chemie (International Ed. in English). 39: 1303-1306. PMID 10767039 DOI: 10.1002/(Sici)1521-3773(20000403)39:7<1303::Aid-Anie1303>3.0.Co;2-0  1
2000 Cook BN, Bhakta S, Biegel T, Bowman RG, Armstrong JI, Hemmerich S, Bertozzi CR. Differential carbohydrate recognition of two GlcNAc-6-sulfotransferases with possible roles in L-selectin ligand biosynthesis Journal of the American Chemical Society. 122: 8612-8622. DOI: 10.1021/Ja001224K  1
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