George A. Lemieux, Ph.D. - Publications

Affiliations: 
2002 University of California, Berkeley, Berkeley, CA 
Area:
Bioorthogonal chemistry

14/24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Williams KE, Lemieux GA, Hassis ME, Olshen AB, Fisher SJ, Werb Z. Quantitative proteomic analyses of mammary organoids reveals distinct signatures after exposure to environmental chemicals. Proceedings of the National Academy of Sciences of the United States of America. PMID 26903627 DOI: 10.1073/Pnas.1600645113  1
2015 Lemieux GA, Ashrafi K. Neural Regulatory Pathways of Feeding and Fat in Caenorhabditis elegans. Annual Review of Genetics. PMID 26473379 DOI: 10.1146/Annurev-Genet-120213-092244  1
2015 Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K. Kynurenic acid is a nutritional cue that enables behavioral plasticity. Cell. 160: 119-31. PMID 25594177 DOI: 10.1016/J.Cell.2014.12.028  1
2015 Lemieux GA, Ashrafi K. Insights and challenges in using C. elegans for investigation of fat metabolism. Critical Reviews in Biochemistry and Molecular Biology. 50: 69-84. PMID 25228063 DOI: 10.3109/10409238.2014.959890  1
2015 Lemieux GA, Ashrafi K. Aging: Stressing about misplaced fat is a key to longevity Elife. 4. DOI: 10.7554/eLife.10161  1
2013 Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. Plos Biology. 11: e1001712. PMID 24260022 DOI: 10.1371/Journal.Pbio.1001712  1
2012 Barros AG, Liu J, Lemieux GA, Mullaney BC, Ashrafi K. Analyses of C. elegans fat metabolic pathways. Methods in Cell Biology. 107: 383-407. PMID 22226531 DOI: 10.1016/B978-0-12-394620-1.00013-8  1
2011 Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, Werb Z. A whole-organism screen identifies new regulators of fat storage. Nature Chemical Biology. 7: 206-13. PMID 21390037 DOI: 10.1038/Nchembio.534  1
2010 Mullaney BC, Blind RD, Lemieux GA, Perez CL, Elle IC, Faergeman NJ, Van Gilst MR, Ingraham HA, Ashrafi K. Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metabolism. 12: 398-410. PMID 20889131 DOI: 10.1016/J.Cmet.2010.08.013  1
2007 Lemieux GA, Blumenkron F, Yeung N, Zhou P, Williams J, Grammer AC, Petrovich R, Lipsky PE, Moss ML, Werb Z. The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. The Journal of Biological Chemistry. 282: 14836-44. PMID 17389606 DOI: 10.1074/Jbc.M608414200  1
2003 Lemieux GA, De Graffenried CL, Bertozzi CR. A fluorogenic dye activated by the staudinger ligation. Journal of the American Chemical Society. 125: 4708-9. PMID 12696879 DOI: 10.1021/Ja029013Y  1
2001 Lemieux GA, Bertozzi CR. Modulating cell surface immunoreactivity by metabolic induction of unnatural carbohydrate antigens. Chemistry & Biology. 8: 265-75. PMID 11306351 DOI: 10.1016/S1074-5521(01)00008-4  1
1999 Lemieux GA, Yarema KJ, Jacobs CL, Bertozzi CR. Exploiting differences in sialoside expression for selective targeting of MRI contrast reagents Journal of the American Chemical Society. 121: 4278-4279. DOI: 10.1021/Ja984228M  1
1998 Lemieux GA, Bertozzi CR. Chemoselective ligation reactions with proteins, oligosaccharides and cells. Trends in Biotechnology. 16: 506-13. PMID 9881482 DOI: 10.1016/S0167-7799(98)01230-X  1
Low-probability matches
2020 Lin L, Lemieux GA, Enogieru OJ, Giacomini KM, Ashrafi K. Neural production of kynurenic acid in requires the AAT-1 transporter. Genes & Development. PMID 32675325 DOI: 10.1101/Gad.339119.120  0.04
2020 Chen WW, Lemieux GA, Camp CH, Chang TC, Ashrafi K, Cicerone MT. Spectroscopic coherent Raman imaging of Caenorhabditis elegans reveals lipid particle diversity. Nature Chemical Biology. PMID 32572275 DOI: 10.1038/S41589-020-0565-2  0.04
2020 Littlepage LE, Ewald AJ, Alexander C, Casbon A, Lu P, Kessenbrock K, Provot S, Phillips JJ, Kouros-Mehr H, Chan M, Welm B, Lilla JN, Chou J, Lawson D, Lemieux G, et al. Zena Werb (1945–2020) Cell Stem Cell. 27: 356-358. DOI: 10.1016/J.Stem.2020.08.006  0.04
2020 Littlepage LE, Ewald AJ, Alexander C, Casbon A, Lu P, Kessenbrock K, Provot S, Phillips JJ, Kouros-Mehr H, Chan M, Welm B, Lilla JN, Chou J, Lawson D, Lemieux G, et al. Zena Werb (1945–2020) Developmental Cell. 54: 299-301. DOI: 10.1016/J.Devcel.2020.07.012  0.04
2018 Vohra M, Lemieux GA, Lin L, Ashrafi K. Kynurenic acid accumulation underlies learning and memory impairment associated with aging. Genes & Development. PMID 29386332 DOI: 10.1101/Gad.307918.117  0.08
2017 Vohra M, Lemieux GA, Lin L, Ashrafi K. The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite. Plos Biology. 15: e2002032. PMID 28763436 DOI: 10.1371/Journal.Pbio.2002032  0.04
2017 Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, et al. Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target. Plos Neglected Tropical Diseases. 11: e0005680. PMID 28704396 DOI: 10.1371/Journal.Pntd.0005680  0.04
2016 Lemieux GA, Ashrafi K. Investigating Connections between Metabolism, Longevity, and Behavior in Caenorhabditis elegans. Trends in Endocrinology and Metabolism: Tem. PMID 27289335 DOI: 10.1016/J.Tem.2016.05.004  0.04
2015 Lemieux GA, Ashrafi K. Stressing about misplaced fat is a key to longevity. Elife. 4. PMID 26287524 DOI: 10.7554/Elife.10161  0.04
2014 Min J, Attia RN, Arnold LA, Teske K, Connelly M, Lemieux G, Ashrafi K, Shelat A, Guy RK. Abstract 5389: Discovery of small molecule inhibitors of the interaction between PPARγ and SMRT Cancer Research. 74: 5389-5389. DOI: 10.1158/1538-7445.Am2014-5389  0.04
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