David I. Rabuka, Ph.D. - Publications

Affiliations: 
2008 University of California, Berkeley, Berkeley, CA 
Area:
Bioorthogonal chemistry

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Harel ET, Drake PM, Barfield RM, Lui I, Farr-Jones S, Van't Veer L, Gartner ZJ, Green EM, Lourenço AL, Cheng Y, Hann BC, Rabuka D, Craik CS. Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer. Antibodies (Basel, Switzerland). 8. PMID 31694242 DOI: 10.3390/Antib8040054  0.56
2019 Walker JA, Sorkin MR, Ledesma F, Kabaria SR, Barfield RM, Rabuka D, Alabi CA. Hydrophilic sequence-defined crosslinkers for antibody-drug conjugates. Bioconjugate Chemistry. PMID 31671265 DOI: 10.1021/Acs.Bioconjchem.9B00713  0.4
2019 Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC. CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity. Nature Chemical Biology. PMID 31451760 DOI: 10.1038/S41589-019-0342-2  0.8
2019 Bauzon M, Drake PM, Barfield RM, Cornali BM, Rupniewski I, Rabuka D. Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells Oncoimmunology. 8. PMID 30906660 DOI: 10.1080/2162402X.2019.1565859  0.4
2018 Linz T, Yeo D, Hong Q, Zmolek W, McFarland J, Barfield RM, Haskins WE, Rabuka D. Systematic LC/MS/MS Investigations for the IND-Enabling Extended Characterization of Antibody-Drug Conjugate Modifications. Antibodies (Basel, Switzerland). 7. PMID 31544890 DOI: 10.3390/Antib7040040  0.4
2018 Huang BCB, Kim YC, Bañas S, Barfield RM, Drake PM, Rupniewski I, Haskins WE, Rabuka D. Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions. Mabs. 1-8. PMID 30252630 DOI: 10.1080/19420862.2018.1512327  0.4
2017 Drake PM, Carlson A, McFarland JM, Banas S, Barfield RM, Zmolek W, Kim YC, Huang BCB, Kudirka R, Rabuka D. CAT-02-106, a site-specifically conjugated anti-CD22 antibody bearing an MDR1-resistant maytansine payload yields excellent efficacy and safety in preclinical models. Molecular Cancer Therapeutics. PMID 29142069 DOI: 10.1158/1535-7163.Mct-17-0776  0.56
2016 Kudirka RA, Barfield RM, McFarland JM, Drake PM, Carlson A, Bañas S, Zmolek W, Garofalo AW, Rabuka D. Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates. Acs Medicinal Chemistry Letters. 7: 994-998. PMID 27882197 DOI: 10.1021/Acsmedchemlett.6B00253  0.56
2016 Zmolek W, Bañas S, Barfield RM, Rabuka D, Drake PM. A simple LC/MRM-MS-based method to quantify free linker-payload in antibody-drug conjugate preparations. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. PMID 27311685 DOI: 10.1016/J.Jchromb.2016.05.055  0.8
2015 Liu J, Hanne J, Britton BM, Shoffner M, Albers AE, Bennett J, Zatezalo R, Barfield R, Rabuka D, Lee JB, Fishel R. An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore. Scientific Reports. 5: 16883. PMID 26582263 DOI: 10.1038/Srep16883  0.8
2015 Kudirka R, Barfield RM, McFarland J, Albers AE, de Hart GW, Drake PM, Holder PG, Banas S, Jones LC, Garofalo AW, Rabuka D. Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation. Chemistry & Biology. 22: 293-8. PMID 25619935 DOI: 10.1016/J.Chembiol.2014.11.019  0.8
2014 Albers AE, Garofalo AW, Drake PM, Kudirka R, de Hart GW, Barfield RM, Baker J, Banas S, Rabuka D. Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates. European Journal of Medicinal Chemistry. 88: 3-9. PMID 25176286 DOI: 10.1016/J.Ejmech.2014.08.062  0.8
2014 Liang SI, McFarland JM, Rabuka D, Gartner ZJ. A modular approach for assembling aldehyde-tagged proteins on DNA scaffolds. Journal of the American Chemical Society. 136: 10850-3. PMID 25029632 DOI: 10.1021/Ja504711N  0.8
2014 Drake PM, Albers AE, Baker J, Banas S, Barfield RM, Bhat AS, de Hart GW, Garofalo AW, Holder P, Jones LC, Kudirka R, McFarland J, Zmolek W, Rabuka D. Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes. Bioconjugate Chemistry. 25: 1331-41. PMID 24924618 DOI: 10.1021/Bc500189Z  0.8
2013 Agarwal P, Kudirka R, Albers AE, Barfield RM, de Hart GW, Drake PM, Jones LC, Rabuka D. Hydrazino-Pictet-Spengler ligation as a biocompatible method for the generation of stable protein conjugates. Bioconjugate Chemistry. 24: 846-51. PMID 23731037 DOI: 10.1021/Bc400042A  0.8
2012 Rabuka D, Rush JS, deHart GW, Wu P, Bertozzi CR. Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nature Protocols. 7: 1052-67. PMID 22576105 DOI: 10.1038/Nprot.2012.045  0.8
2012 Hudak JE, Barfield RM, de Hart GW, Grob P, Nogales E, Bertozzi CR, Rabuka D. Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angewandte Chemie (International Ed. in English). 51: 4161-5. PMID 22407566 DOI: 10.1002/Anie.201108130  0.8
2009 Godula K, Umbel ML, Rabuka D, Botyanszki Z, Bertozzi CR, Parthasarathy R. Control of the molecular orientation of membrane-anchored biomimetic glycopolymers. Journal of the American Chemical Society. 131: 10263-8. PMID 19580278 DOI: 10.1021/Ja903114G  0.8
2009 Godula K, Rabuka D, Nam KT, Bertozzi CR. Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications. Angewandte Chemie (International Ed. in English). 48: 4973-6. PMID 19479916 DOI: 10.1002/Anie.200805756  0.8
2009 Harland CW, Botyanszki Z, Rabuka D, Bertozzi CR, Parthasarathy R. Synthetic trehalose glycolipids confer desiccation resistance to supported lipid monolayers. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 5193-8. PMID 19323499 DOI: 10.1021/La804007A  0.8
2009 Wu P, Shui W, Carlson BL, Hu N, Rabuka D, Lee J, Bertozzi CR. Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proceedings of the National Academy of Sciences of the United States of America. 106: 3000-5. PMID 19202059 DOI: 10.1073/Pnas.0807820106  0.8
2008 Rabuka D, Forstner MB, Groves JT, Bertozzi CR. Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. Journal of the American Chemical Society. 130: 5947-53. PMID 18402449 DOI: 10.1021/Ja710644G  0.8
2008 Harland CW, Rabuka D, Bertozzi CR, Parthasarathy R. The Mycobacterium tuberculosis virulence factor trehalose dimycolate imparts desiccation resistance to model mycobacterial membranes. Biophysical Journal. 94: 4718-24. PMID 18326657 DOI: 10.1529/Biophysj.107.125542  0.8
2007 Parthasarathy R, Rabuka D, Bertozzi CR, Groves JT. Molecular orientation of membrane-anchored mucin glycoprotein mimics. The Journal of Physical Chemistry. B. 111: 12133-5. PMID 17915910 DOI: 10.1021/Jp072136Q  0.8
2007 Rabuka D, Parthasarathy R, Lee GS, Chen X, Groves JT, Bertozzi CR. Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers. Journal of the American Chemical Society. 129: 5462-71. PMID 17425309 DOI: 10.1021/Ja067819I  0.8
2006 Rabuka D, Hubbard SC, Laughlin ST, Argade SP, Bertozzi CR. A chemical reporter strategy to probe glycoprotein fucosylation. Journal of the American Chemical Society. 128: 12078-9. PMID 16967952 DOI: 10.1021/Ja064619Y  0.8
2006 Chen X, Tam UC, Czlapinski JL, Lee GS, Rabuka D, Zettl A, Bertozzi CR. Interfacing carbon nanotubes with living cells. Journal of the American Chemical Society. 128: 6292-3. PMID 16683774 DOI: 10.1021/Ja060276S  0.8
2005 Liang CH, Romero A, Rabuka D, Sgarbi PW, Marby KA, Duffield J, Yao S, Cheng ML, Ichikawa Y, Sears P, Hu C, Hwang SB, Shue YK, Sucheck SJ. Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. Bioorganic & Medicinal Chemistry Letters. 15: 2123-8. PMID 15808482 DOI: 10.1016/J.Bmcl.2005.02.029  0.8
2005 Romero A, Liang CH, Chiu YH, Yao S, Duffield J, Sucheck SJ, Marby K, Rabuka D, Leung PY, Shue YK, Ichikawa Y, Hwang CK. An efficient entry to new sugar modified ketolide antibiotics Tetrahedron Letters. 46: 1483-1487. DOI: 10.1016/J.Tetlet.2005.01.023  0.8
2004 Yao S, Sgarbi PW, Marby KA, Rabuka D, O'Hare SM, Cheng ML, Bairi M, Hu C, Hwang SB, Hwang CK, Ichikawa Y, Sears P, Sucheck SJ. Glyco-optimization of aminoglycosides: new aminoglycosides as novel anti-infective agents. Bioorganic & Medicinal Chemistry Letters. 14: 3733-8. PMID 15203152 DOI: 10.1016/J.Bmcl.2004.05.004  0.8
2004 Agnelli F, Sucheck SJ, Marby KA, Rabuka D, Yao SL, Sears PS, Liang FS, Wong CH. Dimeric aminoglycosides as antibiotics. Angewandte Chemie (International Ed. in English). 43: 1562-6. PMID 15022234 DOI: 10.1002/Anie.200353225  0.8
2002 Bryan MC, Plettenburg O, Sears P, Rabuka D, Wacowich-Sgarbi S, Wong CH. Saccharide display on microtiter plates. Chemistry & Biology. 9: 713-20. PMID 12079783 DOI: 10.1016/S1074-5521(02)00155-2  0.8
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