| Year |
Citation |
Score |
| 2011 |
Miller CP, Shomali M, Lyttle CR, O'Dea LS, Herendeen H, Gallacher K, Paquin D, Compton DR, Sahoo B, Kerrigan SA, Burge MS, Nickels M, Green JL, Katzenellenbogen JA, Tchesnokov A, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. Acs Medicinal Chemistry Letters. 2: 124-9. PMID 24900290 DOI: 10.1021/Ml1002508 |
0.428 |
|
| 2007 |
Zhou HB, Sheng S, Compton DR, Kim Y, Joachimiak A, Sharma S, Carlson KE, Katzenellenbogen BS, Nettles KW, Greene GL, Katzenellenbogen JA. Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. Journal of Medicinal Chemistry. 50: 399-403. PMID 17228884 DOI: 10.1021/Jm061035Y |
0.595 |
|
| 2004 |
Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. Journal of Medicinal Chemistry. 47: 5872-93. PMID 15537344 DOI: 10.1021/Jm049631K |
0.623 |
|
| 2004 |
Compton DR, Carlson KE, Katzenellenbogen JA. Pyrazolo[1,5-a]pyrimidines as estrogen receptor ligands: defining the orientation of a novel heterocyclic core. Bioorganic & Medicinal Chemistry Letters. 14: 5681-4. PMID 15482947 DOI: 10.1016/J.Bmcl.2004.08.046 |
0.593 |
|
| 1999 |
Járai Z, Wagner JA, Varga K, Lake KD, Compton DR, Martin BR, Zimmer AM, Bonner TI, Buckley NE, Mezey E, Razdan RK, Zimmer A, Kunos G. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 96: 14136-41. PMID 10570211 DOI: 10.1073/pnas.96.24.14136 |
0.5 |
|
| 1998 |
Wiley JL, Compton DR, Dai D, Lainton JA, Phillips M, Huffman JW, Martin BR. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 285: 995-1004. PMID 9618400 |
0.333 |
|
| 1998 |
Adams IB, Compton DR, Martin BR. Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 284: 1209-17. PMID 9495885 |
0.387 |
|
| 1997 |
Reggio PH, Wang T, Brown AE, Fleming DN, Seltzman HH, Griffin G, Pertwee RG, Compton DR, Abood ME, Martin BR. Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: synthesis and characterization of a series of O,2-propano-delta 8-tetrahydrocannabinol analogs. Journal of Medicinal Chemistry. 40: 3312-8. PMID 9379452 DOI: 10.1021/Jm970136G |
0.345 |
|
| 1997 |
Seltzman HH, Fleming DN, Thomas BF, Gilliam AF, McCallion DS, Pertwee RG, Compton DR, Martin BR. Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. Journal of Medicinal Chemistry. 40: 3626-34. PMID 9357529 DOI: 10.1021/Jm9702950 |
0.395 |
|
| 1997 |
Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs). Bioorganic & Medicinal Chemistry. 5: 1591-600. PMID 9313864 DOI: 10.1016/S0968-0896(97)00111-9 |
0.407 |
|
| 1997 |
Lake KD, Compton DR, Varga K, Martin BR, Kunos G. Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. 281: 1030-7. PMID 9190833 |
0.454 |
|
| 1996 |
Wiley JL, Compton DR, Gordon PM, Siegel C, Singer M, Dutta A, Lichtman AH, Balster RL, Razdan RK, Martin BR. Evaluation of agonist-antagonist properties of nitrogen mustard and cyano derivatives of delta 8-tetrahydrocannabinol. Neuropharmacology. 35: 1793-804. PMID 9076759 DOI: 10.1016/S0028-3908(96)00120-7 |
0.349 |
|
| 1996 |
Pertwee RG, Fernando SR, Griffin G, Ryan W, Razdan RK, Compton DR, Martin BR. Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. European Journal of Pharmacology. 315: 195-201. PMID 8960884 DOI: 10.1016/S0014-2999(96)00631-0 |
0.303 |
|
| 1996 |
Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH. Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. Journal of Medicinal Chemistry. 39: 3875-7. PMID 8831752 DOI: 10.1021/Jm960394Y |
0.553 |
|
| 1996 |
Showalter VM, Compton DR, Martin BR, Abood ME. Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. The Journal of Pharmacology and Experimental Therapeutics. 278: 989-99. PMID 8819477 |
0.6 |
|
| 1996 |
Compton DR, Aceto MD, Lowe J, Martin BR. In vivo characterization of a specific cannabinoid receptor antagonist (SR141716A): inhibition of delta 9-tetrahydrocannabinol-induced responses and apparent agonist activity. The Journal of Pharmacology and Experimental Therapeutics. 277: 586-94. PMID 8627535 |
0.447 |
|
| 1996 |
Lake KP, Varga K, Compton DR, Kunos G. Anandamide and other cannabinoids mediate hypotension via a cblike receptor in anesthetized rats Faseb Journal. 10: A711. |
0.377 |
|
| 1995 |
Martin BR, Compton DR, Prescott WR, Barrett RL, Razdan RK. Pharmacological evaluation of dimethylheptyl analogs of delta 9-THC: reassessment of the putative three-point cannabinoid-receptor interaction. Drug and Alcohol Dependence. 37: 231-40. PMID 7796717 DOI: 10.1016/0376-8716(94)01081-U |
0.399 |
|
| 1995 |
Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK, Martin BR. Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. The Journal of Pharmacology and Experimental Therapeutics. 273: 1172-81. PMID 7791088 |
0.504 |
|
| 1995 |
Adams IB, Ryan W, Singer M, Razdan RK, Compton DR, Martin BR. Pharmacological and behavioral evaluation of alkylated anandamide analogs. Life Sciences. 56: 2041-8. PMID 7776830 DOI: 10.1016/0024-3205(95)00187-B |
0.304 |
|
| 1995 |
Ryan W, Singer M, Razdan RK, Compton DR, Martin BR. A novel class of potent tetrahydrocannabinols (THCS): 2'-yne-delta 8- and delta 9-THCS. Life Sciences. 56: 2013-20. PMID 7776826 DOI: 10.1016/0024-3205(95)00183-7 |
0.431 |
|
| 1994 |
McLaughlin CR, Martin BR, Compton DR, Abood ME. Cannabinoid receptors in developing rats: detection of mRNA and receptor binding. Drug and Alcohol Dependence. 36: 27-31. PMID 7988356 DOI: 10.1016/0376-8716(94)90006-X |
0.482 |
|
| 1994 |
Huffman JW, Dai D, Martin BR, Compton DR. Design, Synthesis and Pharmacology of Cannabimimetic Indoles Bioorganic and Medicinal Chemistry Letters. 4: 563-566. DOI: 10.1016/S0960-894X(01)80155-4 |
0.423 |
|
| 1993 |
Compton DR, Rice KC, De Costa BR, Razdan RK, Melvin LS, Johnson MR, Martin BR. Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities. The Journal of Pharmacology and Experimental Therapeutics. 265: 218-26. PMID 8474008 |
0.388 |
|
| 1992 |
Charalambous A, Yan G, Houston DB, Howlett AC, Compton DR, Martin BR, Makriyannis A. 5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor. Journal of Medicinal Chemistry. 35: 3076-9. PMID 1323683 DOI: 10.1021/Jm00094A023 |
0.455 |
|
| 1991 |
Thomas BF, Compton DR, Martin BR, Semus SF. Modeling the cannabinoid receptor: a three-dimensional quantitative structure-activity analysis. Molecular Pharmacology. 40: 656-65. PMID 1944237 |
0.366 |
|
| 1991 |
Martin BR, Compton DR, Thomas BF, Prescott WR, Little PJ, Razdan RK, Johnson MR, Melvin LS, Mechoulam R, Ward SJ. Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs. Pharmacology, Biochemistry, and Behavior. 40: 471-8. PMID 1666911 DOI: 10.1016/0091-3057(91)90349-7 |
0.317 |
|
| 1991 |
Compton DR, Prescott WR, Martin BR, Siegel C, Gordon PM, Razdan RK. Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol. Journal of Medicinal Chemistry. 34: 3310-6. PMID 1659638 DOI: 10.1021/Jm00115A023 |
0.373 |
|
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