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Jung-Mo Ahn, Ph.D. - Publications

Affiliations: 
2000 University of Arizona, Tucson, AZ 
 2004- University of Texas at Dallas, Richardson, TX, United States 
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
Website:
https://www.utdallas.edu/chemistry/faculty/ahn.html

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lee TK, Ravindranathan P, Sonavane R, Raj GV, Ahn JM. A Structure-Activity Relationship Study of Bis-Benzamides as Inhibitors of Androgen Receptor-Coactivator Interaction. Molecules (Basel, Switzerland). 24. PMID 31370197 DOI: 10.3390/molecules24152783  1
2017 Goodwin J, Choi H, Hsieh MH, Neugent ML, Ahn JM, Hayenga HN, Singh PK, Shackelford DB, Lee IK, Shulaev V, Dhar S, Takeda N, Kim JW. Targeting HIF-1α/PDK1 Axis by Dichloroacetate (DCA) Suppresses Bleomycin-induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 28915065 DOI: 10.1165/rcmb.2016-0186OC  1
2017 Raj GV, Sareddy GR, Ma S, Lee TK, Viswanadhapalli S, Li R, Liu X, Murakami S, Chen CC, Lee WR, Mann M, Krishnan SR, Manandhar B, Gonugunta VK, Strand D, ... ... Ahn JM, et al. Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers. Elife. 6. PMID 28786813 DOI: 10.7554/eLife.26857  1
2017 Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, ... ... Ahn JM, et al. The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition. Nature Communications. 8: 15503. PMID 28548087 DOI: 10.1038/ncomms15503  1
2016 Graaf C, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, Ahn JM, Liao J, Fletcher MM, Yang D, Brown AJ, Zhou C, Deng J, Wang MW. Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes. Pharmacological Reviews. 68: 954-1013. PMID 27630114 DOI: 10.1124/pr.115.011395  1
2015 Toocheck C, Clister T, Shupe J, Crum C, Ravindranathan P, Lee TK, Ahn JM, Raj GV, Sukhwani M, Orwig KE, Walker WH. Mouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling. Biology of Reproduction. PMID 26607719 DOI: 10.1095/biolreprod.115.132068  1
2015 Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis CM, Um SW, Kim DH, Ahn JM, et al. Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker. Cancer Prevention Research (Philadelphia, Pa.). PMID 26511490 DOI: 10.1158/1940-6207.CAPR-14-0287  1
2015 Manandhar B, Ahn JM. Glucagon-like peptide-1 (GLP-1) analogs: recent advances, new possibilities, and therapeutic implications. Journal of Medicinal Chemistry. 58: 1020-37. PMID 25349901 DOI: 10.1021/jm500810s  0.12
2014 Grabowska MM, Elliott AD, DeGraff DJ, Anderson PD, Anumanthan G, Yamashita H, Sun Q, Friedman DB, Hachey DL, Yu X, Sheehan JH, Ahn JM, Raj GV, Piston DW, Gronostajski RM, et al. NFI transcription factors interact with FOXA1 to regulate prostate-specific gene expression. Molecular Endocrinology (Baltimore, Md.). 28: 949-64. PMID 24801505 DOI: 10.1210/me.2013-1213  1
2014 Akram ON, DeGraff DJ, Sheehan JH, Tilley WD, Matusik RJ, Ahn JM, Raj GV. Tailoring peptidomimetics for targeting protein-protein interactions. Molecular Cancer Research : McR. 12: 967-78. PMID 24642350 DOI: 10.1158/1541-7786.MCR-13-0611  1
2013 Ravindranathan P, Lee TK, Yang L, Centenera MM, Butler L, Tilley WD, Hsieh JT, Ahn JM, Raj GV. Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer. Nature Communications. 4: 1923. PMID 23715282 DOI: 10.1038/ncomms2912  1
2013 Wadajkar AS, Menon JU, Tsai YS, Gore C, Dobin T, Gandee L, Kangasniemi K, Takahashi M, Manandhar B, Ahn JM, Hsieh JT, Nguyen KT. Prostate cancer-specific thermo-responsive polymer-coated iron oxide nanoparticles. Biomaterials. 34: 3618-25. PMID 23419645 DOI: 10.1016/j.biomaterials.2013.01.062  1
2012 Makala L, Di Maro S, Lou TF, Sivanand S, Ahn JM, Pace BS. FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors. Anemia. 2012: 428137. PMID 22655179 DOI: 10.1155/2012/428137  1
2012 Roy S, Chakravarty D, Cortez V, De Mukhopadhyay K, Bandyopadhyay A, Ahn JM, Raj GV, Tekmal RR, Sun L, Vadlamudi RK. Significance of PELP1 in ER-negative breast cancer metastasis. Molecular Cancer Research : McR. 10: 25-33. PMID 22086908 DOI: 10.1158/1541-7786.MCR-11-0456  1
2011 Gao H, Niu G, Yang M, Quan Q, Ma Y, Murage EN, Ahn JM, Kiesewetter DO, Chen X. PET of insulinoma using ¹⁸F-FBEM-EM3106B, a new GLP-1 analogue. Molecular Pharmaceutics. 8: 1775-82. PMID 21800885 DOI: 10.1021/mp200141x  1
2011 Lee TK, Ahn JM. Solid-phase synthesis of tris-benzamides as α-helix mimetics. Acs Combinatorial Science. 13: 107-11. PMID 21395339 DOI: 10.1021/co100056c  1
2010 Murage EN, Gao G, Bisello A, Ahn JM. Development of potent glucagon-like peptide-1 agonists with high enzyme stability via introduction of multiple lactam bridges. Journal of Medicinal Chemistry. 53: 6412-20. PMID 20687610 DOI: 10.1021/jm100602m  1
2009 Marimganti S, Cheemala MN, Ahn JM. Novel amphiphilic alpha-helix mimetics based on a bis-benzamide scaffold. Organic Letters. 11: 4418-21. PMID 19719090 DOI: 10.1021/ol901785v  0.01
2009 Murage E, Beinborn M, Ahn JM. Seeking for alpha-helical propensity in a receptor-bound conformation of glucagon-like peptide-1. Advances in Experimental Medicine and Biology. 611: 289-90. PMID 19400196  1
2009 Ahn JM, Han SY, Murage E, Beinborn M. Rational design of peptidomimetics for class B GPCRs: potent non-peptide GLP-1 receptor agonists. Advances in Experimental Medicine and Biology. 611: 125-6. PMID 19400122  1
2009 Han SY, Beinborn M, Ahn JM. Facile synthesis of glucagon-like peptide-1 (GLP-1) mimetics. Advances in Experimental Medicine and Biology. 611: 119-20. PMID 19400120 DOI: 10.1007/978-0-387-73657-0_53  1
2009 Di Maro S, Ahn JM. Development of an efficient solid-phase synthetic methodology to construct a combinatorial library of a potent HDAC inhibitor. Advances in Experimental Medicine and Biology. 611: 17-8. PMID 19400075  1
2008 Murage EN, Schroeder JC, Beinborn M, Ahn JM. Search for alpha-helical propensity in the receptor-bound conformation of glucagon-like peptide-1. Bioorganic & Medicinal Chemistry. 16: 10106-12. PMID 18952440 DOI: 10.1016/j.bmc.2008.10.006  1
2008 Di Maro S, Pong RC, Hsieh JT, Ahn JM. Efficient solid-phase synthesis of FK228 analogues as potent antitumoral agents. Journal of Medicinal Chemistry. 51: 6639-41. PMID 18839938 DOI: 10.1021/jm800959f  1
2008 Ahn JM, Bode JW. A bright future for peptide science!! Biopolymers - Peptide Science Section. 90: 480. PMID 18561308 DOI: 10.1002/bip.21027  1
2004 Ahn JM, Wentworth P, Janda KD. Probing lipase/esterase libraries for lipid A hydrolases--discovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein. Chemical Communications (Cambridge, England). 364-5. PMID 14765210 DOI: 10.1039/b312662e  1
2003 Moss JA, Coyle AR, Ahn JM, Meijler MM, Offer J, Janda KD. Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody. Journal of Immunological Methods. 281: 143-8. PMID 14580888  1
2003 Ahn JM, Wentworth P, Janda KD. Soluble polymer-supported convergent parallel library synthesis. Chemical Communications (Cambridge, England). 480-1. PMID 12638959  1
2003 Ying J, Ahn JM, Jacobsen NE, Brown MF, Hruby VJ. NMR solution structure of the glucagon antagonist [desHis1, desPhe6, Glu9]glucagon amide in the presence of perdeuterated dodecylphosphocholine micelles. Biochemistry. 42: 2825-35. PMID 12627948 DOI: 10.1021/bi026629r  1
2002 Ahn JM, Boyle NA, MacDonald MT, Janda KD. Peptidomimetics and peptide backbone modifications. Mini Reviews in Medicinal Chemistry. 2: 463-73. PMID 12370047  1
2002 Moens K, Berger V, Ahn JM, Van Schravendijk C, Hruby VJ, Pipeleers D, Schuit F. Assessment of the role of interstitial glucagon in the acute glucose secretory responsiveness of in situ pancreatic beta-cells. Diabetes. 51: 669-75. PMID 11872665  1
2002 Cowell SM, Balse-Srinivasan PM, Ahn JM, Hruby VJ. Design and synthesis of peptide antagonists and inverse agonists for G protein-coupled receptors. Methods in Enzymology. 343: 49-72. PMID 11665587 DOI: 10.1016/S0076-6879(02)43127-8  1
2001 Ahn JM, Gitu PM, Medeiros M, Swift JR, Trivedi D, Hruby VJ. A new approach to search for the bioactive conformation of glucagon: positional cyclization scanning. Journal of Medicinal Chemistry. 44: 3109-16. PMID 11543679  1
2001 Ahn JM, Medeiros M, Trivedi D, Hruby VJ. Development of potent glucagon antagonists: structure-activity relationship study of glycine at position 4. The Journal of Peptide Research : Official Journal of the American Peptide Society. 58: 151-8. PMID 11532074  1
2001 Ahn JM, Medeiros M, Trivedi D, Hruby VJ. Development of potent truncated glucagon antagonists. Journal of Medicinal Chemistry. 44: 1372-9. PMID 11311060  1
2000 Trivedi D, Lin Y, Ahn JM, Siegel M, Mollova NN, Schram KH, Hruby VJ. Design and synthesis of conformationally constrained glucagon analogues. Journal of Medicinal Chemistry. 43: 1714-22. PMID 10794689  1
1998 Sturm NS, Lin Y, Burley SK, Krstenansky JL, Ahn JM, Azizeh BY, Trivedi D, Hruby VJ. Structure-function studies on positions 17, 18, and 21 replacement analogues of glucagon: the importance of charged residues and salt bridges in glucagon biological activity. Journal of Medicinal Chemistry. 41: 2693-700. PMID 9667960 DOI: 10.1021/jm980084a  1
1997 Hruby VJ, Ahn JM, Liao S. Synthesis of oligopeptide and peptidomimetic libraries. Current Opinion in Chemical Biology. 1: 114-9. PMID 9667835  1
1997 Azizeh BY, Ahn JM, Caspari R, Shenderovich MD, Trivedi D, Hruby VJ. The role of phenylalanine at position 6 in glucagon's mechanism of biological action: multiple replacement analogues of glucagon. Journal of Medicinal Chemistry. 40: 2555-62. PMID 9258362 DOI: 10.1021/jm960800d  1
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