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Jung-Mo Ahn, Ph.D. - Related publications

2000 University of Arizona, Tucson, AZ 
 2004- University of Texas at Dallas, Richardson, TX, United States 
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Sereti E, Tsimplouli C, Kalaitsidou E, Sakellaridis N, Dimas K. Study of the Relationship between Sigma Receptor Expression Levels and Some Common Sigma Ligand Activity in Cancer Using Human Cancer Cell Lines of the NCI-60 Cell Line Panel. Biomedicines. 9. PMID 33466391 DOI: 10.3390/biomedicines9010038   
2021 Dengler DG, Harikumar KG, Pollari S, Sun Q, Brown BT, Shinoki-Iwaya A, Ardecky R, Miller LJ, Sergienko EA. Discovery of small molecule positive allosteric modulators of the secretin receptor. Biochemical Pharmacology. 114451. PMID 33545115 DOI: 10.1016/j.bcp.2021.114451   
2021 Hu ZH, Zhao TS, Liu HY, Lin QX, Tu GG, Yang BW. Synthesis and receptor dependent 4D-QSAR studies of 4,5-dihydro-1,3,4-oxadiazole derivatives targeting cannabinoid receptor. Sar and Qsar in Environmental Research. 1-16. PMID 33618568 DOI: 10.1080/1062936X.2021.1879256   
2021 Abid MSR, Mousavi S, Checco JW. Identifying Receptors for Neuropeptides and Peptide Hormones: Challenges and Recent Progress. Acs Chemical Biology. PMID 33539706 DOI: 10.1021/acschembio.0c00950   
2021 Mi YN, Ping NN, Cao YX. Ligands and Signaling of Mas-Related G Protein-Coupled Receptor-X2 in Mast Cell Activation. Reviews of Physiology, Biochemistry and Pharmacology. PMID 33479839 DOI: 10.1007/112_2020_53   
2021 Fischer A, Häuptli F, Lill MA, Smieško M. Computational Assessment of Combination Therapy of Androgen Receptor-Targeting Compounds. Journal of Chemical Information and Modeling. PMID 33523669 DOI: 10.1021/acs.jcim.0c01194   
2021 Deganutti G, Barkan K, Preti B, Leuenberger M, Wall M, Frenguelli BG, Lochner M, Ladds G, Reynolds CA. Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor. Acs Pharmacology & Translational Science. 4: 314-326. PMID 33615181 DOI: 10.1021/acsptsci.0c00195   
2021 Woods LT, Forti KM, Shanbhag VC, Camden JM, Weisman GA. P2Y receptors for extracellular nucleotides: Contributions to cancer progression and therapeutic implications. Biochemical Pharmacology. 114406. PMID 33412103 DOI: 10.1016/j.bcp.2021.114406   
2021 Branch JR, Bush TL, Pande V, Connolly PJ, Zhang Z, Hickson I, Ondrus J, Jaensch S, Bischoff JR, Habineza G, Van Hecke G, Meerpoel L, Packman K, Parrett CJ, Chong YT, et al. Discovery of JNJ-63576253, a next-generation androgen receptor antagonist active against wild-type and clinically-relevant ligand binding domain mutations in mCRPC. Molecular Cancer Therapeutics. PMID 33649102 DOI: 10.1158/1535-7163.MCT-20-0510   
2021 Moody TW, Jensen RT. Pituitary adenylate cyclase-activating polypeptide /vasoactive intestinal peptide [Part 1]: biology, pharmacology, and new insights into their cellular basis of action/signaling which are providing new therapeutic targets. Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 33449573 DOI: 10.1097/MED.0000000000000617   
2021 Méndez-Luna D, Morelos-Garnica LA, García-Vázquez JB, Bello M, Padilla-Martínez II, Fragoso-Vázquez MJ, Dueñas González A, De Pedro N, Gómez-Vidal JA, Mendoza-Figueroa HL, Correa-Basurto J. Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells. Pharmaceuticals (Basel, Switzerland). 14. PMID 33435260 DOI: 10.3390/ph14010049   
2021 Franzosa JA, Bonzo JA, Jack J, Baker NC, Kothiya P, Witek RP, Hurban P, Siferd S, Hester S, Shah I, Ferguson SS, Houck KA, Wambaugh JF. High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures. Npj Systems Biology and Applications. 7: 7. PMID 33504769 DOI: 10.1038/s41540-020-00166-2   
2021 Deng Z, Liao W, Wei W, Zhong G, He C, Zhang H, Liu Q, Xu X, Liang J, Liu Z. Anlotinib as a promising inhibitor on tumor growth of oral squamous cell carcinoma through cell apoptosis and mitotic catastrophe. Cancer Cell International. 21: 37. PMID 33422069 DOI: 10.1186/s12935-020-01721-x   
2021 Uddin MZ, Paul A, Rakib A, Sami SA, Mahmud S, Rana MS, Hossain S, Tareq AM, Dutta M, Emran TB, Simal-Gandara J. Chemical Profiles and Pharmacological Properties with in Silico Studies on Wedd. Molecules (Basel, Switzerland). 26. PMID 33557235 DOI: 10.3390/molecules26040809   
2021 Mannes M, Martin C, Triest S, Dimmito MP, Mollica A, Laeremans T, Menet CJ, Ballet S. Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs Protein-Coupled Receptors for Application in Drug Discovery. Angewandte Chemie (International Ed. in English). PMID 33596327 DOI: 10.1002/anie.202100180   
2021 Iyer MR, Kunos G. Therapeutic approaches targeting the neurotensin receptors. Expert Opinion On Therapeutic Patents. 1-26. PMID 33393392 DOI: 10.1080/13543776.2021.1866539   
2021 van Waarde A, Marcolini S, de Deyn PP, Dierckx RAJO. PET Agents in Dementia: An Overview. Seminars in Nuclear Medicine. PMID 33500121 DOI: 10.1053/j.semnuclmed.2020.12.008   
2021 Yunn NO, Park M, Park S, Lee J, Noh J, Shin E, Ryu SH. A hotspot for enhancing insulin receptor activation revealed by a conformation-specific allosteric aptamer. Nucleic Acids Research. PMID 33410883 DOI: 10.1093/nar/gkaa1247   
2021 Knerr L, Prakash TP, Lee R, Drury Iii WJ, Nikan M, Fu W, Pirie E, Maria L, Valeur E, Hayen A, Ölwegård-Halvarsson M, Broddefalk J, Ämmälä C, Østergaard ME, Meuller J, et al. Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell. Journal of the American Chemical Society. PMID 33626278 DOI: 10.1021/jacs.0c12043   
2021 Upreti S, Prusty JS, Pandey SC, Kumar A, Samant M. Identification of novel inhibitors of angiotensin-converting enzyme 2 (ACE-2) receptor from Urtica dioica to combat coronavirus disease 2019 (COVID-19). Molecular Diversity. PMID 33398633 DOI: 10.1007/s11030-020-10159-2   
2021 Schüß C, Vu O, Schubert M, Du Y, Mishra NM, Tough IR, Stichel J, Weaver CD, Emmitte KA, Cox HM, Meiler J, Beck-Sickinger AG. Highly Selective Y Receptor Antagonist Binds in an Allosteric Binding Pocket. Journal of Medicinal Chemistry. PMID 33595306 DOI: 10.1021/acs.jmedchem.0c02000   
2021 Ghislain J, Poitout V. Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges. Nature Reviews. Endocrinology. PMID 33495605 DOI: 10.1038/s41574-020-00459-w   
2021 Purawarga Matada GS, Dhiwar PS, Abbas N, Singh E, Ghara A, Das A, Bhargava SV. Molecular docking and molecular dynamic studies: screening of phytochemicals against EGFR, HER2, estrogen and NF-KB receptors for their potential use in breast cancer. Journal of Biomolecular Structure & Dynamics. 1-10. PMID 33525984 DOI: 10.1080/07391102.2021.1877823   
2021 Kimani FW, Ajit J, Galluppi A, Manna S, Howitz WJ, Tang S, Esser-Kahn AP. Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands. Acs Chemical Biology. PMID 33523635 DOI: 10.1021/acschembio.0c00924   
2021 Fischer A, Frehner G, Lill MA, Smieško M. Conformational Changes of Thyroid Receptors in Response to Antagonists. Journal of Chemical Information and Modeling. PMID 33449688 DOI: 10.1021/acs.jcim.0c01403   
2021 Milliken BT, Elfers C, Chepurny OG, Chichura KS, Sweet IR, Borner T, Hayes MR, De Jonghe BC, Holz GG, Roth CL, Doyle RP. Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis. Journal of Medicinal Chemistry. PMID 33449689 DOI: 10.1021/acs.jmedchem.0c01783   
2021 McNeill SM, Baltos JA, White PJ, May LT. Biased agonism at adenosine receptors. Cellular Signalling. 109954. PMID 33610717 DOI: 10.1016/j.cellsig.2021.109954   
2021 Abd Rani NZ, Lam KW, Jalil J, Mohamad HF, Mat Ali MS, Husain K. Mechanistic Studies of the Antiallergic Activity of Schum. & Thonn. and Its Compounds. Molecules (Basel, Switzerland). 26. PMID 33525733 DOI: 10.3390/molecules26030695   
2021 Tang T, Hartig C, Chen Q, Zhao W, Kaiser A, Zhang X, Zhang H, Qu H, Yi C, Ma L, Han S, Zhao Q, Beck-Sickinger AG, Wu B. Structural basis for ligand recognition of the neuropeptide Y Y receptor. Nature Communications. 12: 737. PMID 33531491 DOI: 10.1038/s41467-021-21030-9   
2021 Popli P, Gutterman EM, Omene C, Ganesan S, Mills D, Marlink R. Receptor-Defined Breast Cancer in Five East African Countries and Its Implications for Treatment: Systematic Review and Meta-Analysis. Jco Global Oncology. 7: 289-301. PMID 33591798 DOI: 10.1200/GO.20.00398   
2021 Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parège C, Chiavarina B, Grimaldi M, Le Mével S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianférani S, Fini JB, et al. Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33361153 DOI: 10.1073/pnas.2020551118   
2021 Lin C, Li J, Wu C, Bao J. Identifying selective agonists targeting LXRβ from terpene compounds of alismatis rhizoma. Journal of Molecular Modeling. 27: 91. PMID 33616795 DOI: 10.1007/s00894-021-04699-z   
2021 Bouwman KM, Tomris I, Turner HL, van der Woude R, Shamorkina TM, Bosman GP, Rockx B, Herfst S, Snijder J, Haagmans BL, Ward AB, Boons GJ, de Vries RP. Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins. Plos Pathogens. 17: e1009282. PMID 33556147 DOI: 10.1371/journal.ppat.1009282   
2021 Zvi Y, Ugur E, Batko B, Gill J, Roth M, Gorlick R, Hall D, Tingling J, Barkauskas DA, Zhang J, Yang R, Hoang BH, Geller DS. Prognostic and Therapeutic Utility of Variably Expressed Cell Surface Receptors in Osteosarcoma. Sarcoma. 2021: 8324348. PMID 33603563 DOI: 10.1155/2021/8324348   
2021 Rivas-Santisteban R, Lillo J, Muñoz A, Rodríguez-Pérez AI, Labandeira-García JL, Navarro G, Franco R. Novel Interactions Involving the Mas Receptor Show Potential of the Renin-Angiotensin system in the Regulation of Microglia Activation: Altered Expression in Parkinsonism and Dyskinesia. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33474655 DOI: 10.1007/s13311-020-00986-4   
2021 Vanda D, Canale V, Chaumont-Dubel S, Kurczab R, Satała G, Koczurkiewicz-Adamczyk P, Krawczyk M, Pietruś W, Blicharz K, Pękala E, Bojarski AJ, Popik P, Marin P, Soural M, Zajdel P. Imidazopyridine-Based 5-HT Receptor Neutral Antagonists: Impact of -Benzyl and -Phenylsulfonyl Fragments on Different Receptor Conformational States. Journal of Medicinal Chemistry. PMID 33439019 DOI: 10.1021/acs.jmedchem.0c02009   
2021 Appiah-Kubi P, Olotu FA, Soliman MES. Exploring the structural basis and atomistic binding mechanistic of the selective antagonist blockade at D dopamine receptor over D dopamine receptor. Journal of Molecular Recognition : Jmr. e2885. PMID 33401335 DOI: 10.1002/jmr.2885   
2021 Li J, He K, Ge J, Li C, Jing Z. Efficacy and safety of the glucagon-like peptide-1 receptor agonist oral semaglutide in patients with type 2 diabetes mellitus: a systematic review and meta-analysis. Diabetes Research and Clinical Practice. 108656. PMID 33434602 DOI: 10.1016/j.diabres.2021.108656   
2021 Wang W, Tian Y, Shi X, Ma Q, Xu Y, Yang G, Yi W, Shi Y, Zhou N. N-glycosylation of the human neuropeptide QRFP receptor QRFPR is essential for ligand binding and receptor activation. Journal of Neurochemistry. PMID 33655503 DOI: 10.1111/jnc.15337   
2021 Kline JM, Heusinkveld LE, Taranto E, Martin CB, Tomasi AG, Hsu IJ, Cho K, Khillan JS, Murphy PM, Pontejo SM. Structural and functional analysis of Ccr1l1, a Rodentia-restricted eosinophil-selective chemokine receptor homologue. The Journal of Biological Chemistry. 100373. PMID 33548230 DOI: 10.1016/j.jbc.2021.100373   
2021 Kline JM, Heusinkveld LE, Taranto E, Martin CB, Tomasi AG, Hsu IJ, Cho K, Khillan JS, Murphy PM, Pontejo SM. Structural and functional analysis of Ccr1l1, a Rodentia-restricted eosinophil-selective chemokine receptor homologue. The Journal of Biological Chemistry. 100373. PMID 33548230 DOI: 10.1016/j.jbc.2021.100373   
2021 Bechthold E, Schreiber JA, Lehmkuhl K, Frehland B, Schepmann D, Bernal FA, Daniliuc C, Álvarez I, Garcia CV, Schmidt TJ, Seebohm G, Wünsch B. Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity. Journal of Medicinal Chemistry. PMID 33426889 DOI: 10.1021/acs.jmedchem.0c01912   
2021 Smits MM, Fluitman KS, Herrema H, Davids M, Kramer MHH, Groen AK, Belzer C, de Vos WM, Cahen DL, Nieuwdorp M, van Raalte DH. Liraglutide and sitagliptin have no effect on intestinal microbiota composition: A 12-week randomized placebo-controlled trial in adults with type 2 diabetes. Diabetes & Metabolism. 101223. PMID 33429063 DOI: 10.1016/j.diabet.2021.101223   
2021 Zhang Z, Connolly PJ, Lim HK, Pande V, Meerpoel L, Teleha C, Branch JR, Ondrus J, Hickson I, Bush T, Luistro L, Packman K, Bischoff JR, Ibrahim S, Parrett C, et al. Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC). Journal of Medicinal Chemistry. PMID 33470111 DOI: 10.1021/acs.jmedchem.0c01563   
2021 Meister J, Wang L, Pydi SP, Wess J. Chemogenetic approaches to identify metabolically important GPCR signaling pathways: therapeutic implications. Journal of Neurochemistry. PMID 33540469 DOI: 10.1111/jnc.15314   
2021 Wei L, Hou T, Li J, Zhang X, Zhou H, Wang Z, Cheng J, Xiang K, Wang J, Zhao Y, Liang X. Structure-Activity Relationship Studies of Coumarin-like Diacid Derivatives as Human G Protein-Coupled Receptor-35 (hGPR35) Agonists and a Consequent New Design Principle. Journal of Medicinal Chemistry. PMID 33630609 DOI: 10.1021/acs.jmedchem.0c01624   
2021 Nomoto H, Oba-Yamamoto C, Takahashi Y, Takeuchi J, Nagai S, Yokoyama H, Taneda S, Kurihara Y, Aoki S, Kameda H, Cho KY, Nakamura A, Atsumi T, Miyoshi H. Effects of Switching from Liraglutide or Dulaglutide to Subcutaneous Semaglutide on Glucose Metabolism and Treatment Satisfaction in Patients with Type 2 Diabetes: Protocol for a Multicenter, Prospective, Randomized, Open-Label, Blinded-Endpoint, Parallel-Group Comparison Study (The SWITCH-SEMA 1 Study). Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders. PMID 33491111 DOI: 10.1007/s13300-020-00986-9   
2021 White CW, Kilpatrick LE, Pfleger KDG, Hill SJ. A nanoluciferase biosensor to investigate endogenous chemokine secretion and receptor binding. Iscience. 24: 102011. PMID 33490919 DOI: 10.1016/j.isci.2020.102011   
2021 Arsova A, Møller TC, Hellyer SD, Vedel L, Foster SR, Hansen JL, Bräuner-Osborne H, Gregory KJ. Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias. Molecular Pharmacology. PMID 33602724 DOI: 10.1124/molpharm.120.000185   
2021 Bardia A, Kaklamani V, Wilks S, Weise A, Richards D, Harb W, Osborne C, Wesolowski R, Karuturi M, Conkling P, Bagley RG, Wang Y, Conlan MG, Kabos P. Phase I Study of Elacestrant (RAD1901), a Novel Selective Estrogen Receptor Degrader, in ER-Positive, HER2-Negative Advanced Breast Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2002272. PMID 33513026 DOI: 10.1200/JCO.20.02272