Ravil R. Petrov, Ph.D. - Related publications

2007 University of Arizona, Tucson, AZ 
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Che T, Roth BL. Structural Insights Accelerate the Discovery of Opioid Alternatives. Annual Review of Biochemistry. PMID 33756098 DOI: 10.1146/annurev-biochem-061620-044044   
2021 Seth R, Kuppalli SS, Nadav D, Chen G, Gulati A. Recent Advances in Peripheral Opioid Receptor Therapeutics. Current Pain and Headache Reports. 25: 46. PMID 33970352 DOI: 10.1007/s11916-021-00951-6   
2021 Gonçalves WA, Ferreira RCM, Rezende BM, Mahecha GAB, Gualdron M, de Macedo FHP, Duarte IDG, Perez AC, Machado FS, Cruz JDS, Romero TRL. Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site. European Journal of Pharmacology. 174089. PMID 33826922 DOI: 10.1016/j.ejphar.2021.174089   
2021 Bodnar RJ. Endogenous opiates and behavior: 2019. Peptides. 141: 170547. PMID 33831447 DOI: 10.1016/j.peptides.2021.170547   
2021 Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li MH, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR. Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33846240 DOI: 10.1073/pnas.2000017118   
2021 Ricarte A, Dalton JAR, Giraldo J. Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns. Journal of Chemical Information and Modeling. 61: 1251-1274. PMID 33448226 DOI: 10.1021/acs.jcim.0c00890   
2021 Zaidi SA, Katritch V. Structural Characterization of KOR Inactive and Active States for 3D Pharmacology and Drug Discovery. Handbook of Experimental Pharmacology. PMID 33945028 DOI: 10.1007/164_2021_461   
2021 Lu JJ, Polgar WE, Mann A, Dasgupta P, Schulz S, Zaveri NT. Differential In vitro Pharmacological Profiles of Structurally Diverse Nociceptin Receptor Agonists in Activating G-protein and Beta-arrestin Signaling at the Human Nociceptin Opioid Receptor. Molecular Pharmacology. PMID 33958480 DOI: 10.1124/molpharm.120.000076   
2021 Amelia T, van Veldhoven JPD, Falsini M, Liu R, Heitman LH, van Westen GJP, Segala E, Verdon G, Cheng RKY, Cooke RM, van der Es D, IJzerman AP. Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A Receptor. Journal of Medicinal Chemistry. PMID 33764785 DOI: 10.1021/acs.jmedchem.0c01856   
2021 Jergova S, Perez C, Imperial JS, Gajavelli S, Jain A, Abin A, Olivera BM, Sagen J. Cannabinoid receptor agonists from Conus venoms alleviate pain-related behavior in rats. Pharmacology, Biochemistry, and Behavior. 173182. PMID 33774007 DOI: 10.1016/j.pbb.2021.173182   
2021 Joseph TT, Bu W, Lin W, Zoubak L, Yeliseev A, Liu R, Eckenhoff RG, Brannigan G. Ketamine Metabolite (2,6)-Hydroxynorketamine Interacts with μ and κ Opioid Receptors. Acs Chemical Neuroscience. PMID 33905229 DOI: 10.1021/acschemneuro.0c00741   
2021 Sun X, Zhou Q, Zhou M, Cao R, Chen Z, Tang S, Huang S. The Effect of Epidural Nalbuphine Combined with Ropivacaine on Epidural Analgesia During Labor-- A Multicenter, Randomized, Double-blind, Controlled Study. The Clinical Journal of Pain. PMID 33758132 DOI: 10.1097/AJP.0000000000000928   
2021 Sharma VK, Srivedavyasasri R, Ali Z, Zjawiony JK, Ross SA, Ferreira D, Ashpole N, Khan IA. Rotenoids and Other Specialized Metabolites from the Roots of : Opioid and Cannabinoid Receptor Radioligand Binding Affinities. Journal of Natural Products. PMID 33734684 DOI: 10.1021/acs.jnatprod.0c00939   
2021 Che T, Dwivedi-Agnihotri H, Shukla AK, Roth BL. Biased ligands at opioid receptors: Current status and future directions. Science Signaling. 14. PMID 33824179 DOI: 10.1126/scisignal.aav0320   
2021 Kampen S, Duc Vo D, Zhang X, Panel N, Yang Y, Jaiteh M, Matricon P, Svenningsson P, Brea J, Loza MI, Kihlberg J, Carlsson J. Structure-guided Design of G Protein-coupled Receptor Polypharmacology. Angewandte Chemie (International Ed. in English). PMID 33904641 DOI: 10.1002/anie.202101478   
2021 Liao C, Remington JM, May V, Li J. Molecular Basis of Class B GPCR Selectivity for the Neuropeptides PACAP and VIP. Frontiers in Molecular Biosciences. 8: 644644. PMID 33842547 DOI: 10.3389/fmolb.2021.644644   
2021 Amorim JL, Lima FA, Brand ALM, Cunha S, Rezende CM, Fernandes PD. Two New -Alkanoyl-5-Hydroxytryptamides with Relevant Antinociceptive Activity. Biomedicines. 9. PMID 33922159 DOI: 10.3390/biomedicines9050455   
2021 Grenier P, Sunavsky A, Olmstead MC. Morphine Induces Upregulation of Neuronally Expressed CB2 Receptors in the Spinal Dorsal Horn of Rats. Cannabis and Cannabinoid Research. 6: 137-147. PMID 33912678 DOI: 10.1089/can.2020.0004   
2021 Díaz JL, Cuevas F, Oliva AI, Font D, Sarmentero MÁ, Álvarez-Bercedo P, López-Valbuena JM, Pericàs MA, Enrech R, Montero A, Yeste S, Vidal-Torres A, Álvarez I, Pérez P, Cendán CM, et al. Tricyclic Triazoles as σ Receptor Antagonists for Treating Pain. Journal of Medicinal Chemistry. PMID 33826322 DOI: 10.1021/acs.jmedchem.1c00244   
2021 Mohr F, Hurrle T, Burggraaff L, Langer L, Bemelmans MP, Knab M, Nieger M, van Westen GJP, Heitman LH, Bräse S. Synthesis and SAR evaluation of coumarin derivatives as potent cannabinoid receptor agonists. European Journal of Medicinal Chemistry. 220: 113354. PMID 33915369 DOI: 10.1016/j.ejmech.2021.113354   
2021 Kopp N, Civenni G, Marson D, Laurini E, Pricl S, Catapano CV, Humpf HU, Almansa C, Nieto FR, Schepmann D, Wünsch B. Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ receptor affinity, antitumor and analgesic activity. European Journal of Medicinal Chemistry. 219: 113443. PMID 33901806 DOI: 10.1016/j.ejmech.2021.113443   
2021 Coronado-Álvarez A, Romero-Cordero K, Macías-Triana L, Tatum-Kuri A, Vera-Barrón A, Budde H, Machado S, Yamamoto T, Imperatori C, Murillo-Rodríguez E. The synthetic CB cannabinoid receptor selective agonists: Putative medical uses and their legalization. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110301. PMID 33741446 DOI: 10.1016/j.pnpbp.2021.110301   
2021 Gohda K, Iguchi Y, Masuda A, Fujimori K, Yamashita Y, Teno N. Design and identification of a new farnesoid X receptor (FXR) partial agonist by computational structure-activity relationship analysis: Ligand-induced H8 helix fluctuation in the ligand-binding domain of FXR may lead to partial agonism. Bioorganic & Medicinal Chemistry Letters. 41: 128026. PMID 33839252 DOI: 10.1016/j.bmcl.2021.128026   
2021 Deganutti G, Barkan K, Ladds G, Reynolds CA. Multisite Model of Allosterism for the Adenosine A1 Receptor. Journal of Chemical Information and Modeling. PMID 33779168 DOI: 10.1021/acs.jcim.0c01331   
2021 Macedo-Júnior SJ, Nascimento FP, Luiz-Cerutti M, Santos ARS. The role of peripheral adenosine receptors in glutamate-induced pain nociceptive behavior. Purinergic Signalling. PMID 33860899 DOI: 10.1007/s11302-021-09781-y   
2021 Yun C, Haleem MS, Jeong S, Oyer MA, Driscoll AJ, Chang KY, Yun J, Paul J, Lubbe RJ, Stock SR, Hsu WK, Hsu EL. Effect of Postoperative Analgesic Exposure to the Cannabinoid Receptor Agonist WIN55 on Osteogenic Differentiation and Spinal Fusion in Rats. The Journal of Bone and Joint Surgery. American Volume. PMID 33759484 DOI: 10.2106/JBJS.20.00573   
2021 Butelman ER, Baynard C, McElroy BD, Prisinzano TE, Kreek MJ. Profile of a short-acting κ-antagonist, LY2795050, on self-grooming behaviors, forced swim test and locomotor activity: sex comparison in mice. Journal of Psychopharmacology (Oxford, England). 269881121996883. PMID 33769112 DOI: 10.1177/0269881121996883   
2021 Sellami A, Montes M, Lagarde N. Predicting Potential Endocrine Disrupting Chemicals Binding to Estrogen Receptor α (ERα) Using a Pipeline Combining Structure-Based and Ligand-Based in Silico Methods. International Journal of Molecular Sciences. 22. PMID 33799614 DOI: 10.3390/ijms22062846   
2021 Ma H, Wang H, Gillespie JC, Mendez RE, Selley DE, Zhang Y. Exploring naltrexamine derivatives featuring azaindole moiety via nitrogen-walk approach to investigate their in vitro pharmacological profiles at the mu opioid receptor. Bioorganic & Medicinal Chemistry Letters. 127953. PMID 33766769 DOI: 10.1016/j.bmcl.2021.127953   
2021 Christie S, Zagorodnyuk VP. CB2 cannabinoid receptor agonist selectively inhibits the mechanosensitivity of mucosal afferents in the guinea pig bladder. American Journal of Physiology. Renal Physiology. PMID 33749323 DOI: 10.1152/ajprenal.00065.2021   
2021 Györi J, Kohn AB, Romanova DY, Moroz LL. ATP signaling in the integrative neural center of Aplysia californica. Scientific Reports. 11: 5478. PMID 33750901 DOI: 10.1038/s41598-021-84981-5   
2021 Wang M, Hou S, Wei Y, Li D, Lin J. Discovery of novel dual adenosine A1/A2A receptor antagonists using deep learning, pharmacophore modeling and molecular docking. Plos Computational Biology. 17: e1008821. PMID 33739970 DOI: 10.1371/journal.pcbi.1008821   
2021 Patsch K, Liu C, Zapotoczny G, Sun Y, Sura H, Ung N, Sun RX, Haliday B, Yu C, Aljehani M, Lee JSH, Kashemirov BA, Agus DB, McKenna CE, Ruderman D. Paradoxical androgen receptor regulation by small molecule enantiomers. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33741738 DOI: 10.1073/pnas.2100918118   
2021 Fulo HF, Shoeib A, Cabanlong CV, Williams AH, Zhan CG, Prather PL, Dudley GB. Synthesis, Molecular Pharmacology, and Structure-Activity Relationships of 3-(Indanoyl)indoles as Selective Cannabinoid Type 2 Receptor Antagonists. Journal of Medicinal Chemistry. PMID 33887913 DOI: 10.1021/acs.jmedchem.1c00442   
2021 Houck KA, Patlewicz G, Richard A, Williams AJ, Shobair MA, Smeltz M, Clifton MS, Wetmore B, Medvedev A, Makarov S. Bioactivity Profiling of Per- and Polyfluoroalkyl Substances (PFAS) Identifies Potential Toxicity Pathways Related to Molecular Structure. Toxicology. 152789. PMID 33887376 DOI: 10.1016/j.tox.2021.152789   
2021 McMillan H, Lundy FT, Dunne OM, Al-Natour B, Jeanneau C, About I, Curtis TM, El Karim I. Endogenous Mas-related G-protein-coupled receptor X1 activates and sensitizes TRPA1 in a human model of peripheral nerves. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21492. PMID 33788969 DOI: 10.1096/fj.202001667RR   
2021 Chowrasia D, Jafri A, Azad I, Rais J, Sharma N, Khan F, Kumar A, Kumar S, Arshad M. and growth inhibitory, anti-ovarian & anti-lung carcinoma effects of 1,5 diarylpenta-1,4-dien-3-one as synthetically modified curcumin analogue. Journal of Biomolecular Structure & Dynamics. 1-18. PMID 33955334 DOI: 10.1080/07391102.2021.1914166   
2021 Mingle D, Ospanov M, Radwan MO, Ashpole N, Otsuka M, Ross SA, Walker L, Shilabin AG, Ibrahim MA. First In Class (,)-11-[2-(Arylmethylene)Hydrazono]-PBD Analogs As Selective CB2 Modulators Targeting Neurodegenerative Disorders. Medicinal Chemistry Research : An International Journal For Rapid Communications On Design and Mechanisms of Action of Biologically Active Agents. 30: 98-108. PMID 33776384 DOI: 10.1007/s00044-020-02640-2   
2021 Shivnaraine RV, Kelly B, Elmslie G, Huang XP, Dong YJ, Seidenberg M, Wells JW, Ellis J. Allostery of atypical modulators at oligomeric G protein-coupled receptors. Scientific Reports. 11: 9265. PMID 33927236 DOI: 10.1038/s41598-021-88399-x   
2021 Flynn SM, France CP. Discriminative stimulus effects of carfentanil in rats discriminating fentanyl: Differential antagonism by naltrexone. Drug and Alcohol Dependence. 221: 108599. PMID 33631547 DOI: 10.1016/j.drugalcdep.2021.108599   
2021 Muralidharan A, Samoshkin A, Convertino M, Piltonen MH, Gris P, Wang J, Jiang C, Klares R, Linton A, Ji RR, Maixner W, Dokholyan NV, Mogil JS, Diatchenko L. Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane mu-opioid receptor isoforms. British Journal of Pharmacology. PMID 33782947 DOI: 10.1111/bph.15463   
2021 Reynoso-Moreno I, Tietz S, Vallini E, Engelhardt B, Gertsch J, Chicca A. Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple Sclerosis. Acs Pharmacology & Translational Science. 4: 765-779. PMID 33860200 DOI: 10.1021/acsptsci.0c00214   
2021 Meyer ME, Doshi A, Yasuda D, Zaveri NT. Structure-Based SAR in the Design of Selective or Bifunctional Nociceptin (NOP) Receptor Agonists. The Aaps Journal. 23: 68. PMID 33974173 DOI: 10.1208/s12248-021-00589-7   
2021 Yokoi T, Nabe T, Horoiwa S, Hayashi K, Ito-Harashima S, Yagi T, Nakagawa Y, Miyagawa H. Virtual screening identifies a novel piperazine-based insect juvenile hormone agonist. Journal of Pesticide Science. 46: 68-74. PMID 33746548 DOI: 10.1584/jpestics.D20-074   
2021 Giakomidi D, Bird MF, McDonald J, Marzola E, Guerrini R, Chanoch S, Sabu N, Horley B, Calo G, Lambert DG. Evaluation of [Cys(ATTO 488)8]Dermorphin-NH2 as a novel tool for the study of μ-opioid peptide receptors. Plos One. 16: e0250011. PMID 33891604 DOI: 10.1371/journal.pone.0250011   
2021 Stoddart LA, Kilpatrick LE, Corriden R, Kellam B, Briddon SJ, Hill SJ. Efficient G protein coupling is not required for agonist-mediated internalization and membrane reorganization of the adenosine A receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21211. PMID 33710641 DOI: 10.1096/fj.202001729RR   
2021 Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, et al. Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E receptor EP2 subtype. Science Advances. 7. PMID 33811074 DOI: 10.1126/sciadv.abf1268   
2021 Wang X, Narayan SW, Penm J, Johnstone C, Patanwala AE. Gastrointestinal Adverse Events in Hospitalized Patients Following Orthopedic Surgery: Tapentadol Immediate Release Versus Oxycodone Immediate Release. Pain Physician. 24: E309-E315. PMID 33988952   
2021 Mayer ML. Structural biology of kainate receptors. Neuropharmacology. 108511. PMID 33798545 DOI: 10.1016/j.neuropharm.2021.108511   
2021 Perszyk RE, Yip MC, McConnell OL, Wang ET, Jenkins A, Traynelis SF, Forest CR. Automated intracellular pharmacological electrophysiology for ligand-gated ionotropic receptor and pharmacology screening. Molecular Pharmacology. PMID 33958481 DOI: 10.1124/molpharm.120.000195