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James Cain, Ph.D. - Publications

Affiliations: 
2011 Chemistry University of Arizona, Tucson, AZ 
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang H, Cain JG, Uraco A, Lindstrom E, Johnstone RE. Getting to a New Normal: Mandating That Patients Wear Masks as Hospitals Fully Reopen during the Coronavirus Pandemic: Comment. Anesthesiology. PMID 32780574 DOI: 10.1097/ALN.0000000000003505  0.64
2017 Vardanyan RS, Cain JP, Haghighi SM, Kumirov VK, McIntosh MI, Sandweiss AJ, Porreca F, Hruby VJ. Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain. Journal of Heterocyclic Chemistry. 54: 1228-1235. PMID 28819330 DOI: 10.1002/jhet.2696  0.88
2014 Cain J, Laskin A, Kholghy MR, Thomson MJ, Wang H. Molecular characterization of organic content of soot along the centerline of a coflow diffusion flame. Physical Chemistry Chemical Physics : Pccp. 16: 25862-75. PMID 25354231 DOI: 10.1039/c4cp03330b  0.64
2013 Podolsky AT, Sandweiss A, Hu J, Bilsky EJ, Cain JP, Kumirov VK, Lee YS, Hruby VJ, Vardanyan RS, Vanderah TW. Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain. Life Sciences. 93: 1010-6. PMID 24084045 DOI: 10.1016/j.lfs.2013.09.016  0.88
2012 Guo D, Cain JP, O'Connell S, Gardner ER, Pisle S, Figg WD, Tabibi SE, Yalkowsky SH. Preformulation study of NSC-726796. Aaps Pharmscitech. 13: 661-73. PMID 22552929 DOI: 10.1208/s12249-012-9784-5  0.88
2011 Liu Y, Minofar B, Desyaterik Y, Dames E, Zhu Z, Cain JP, Hopkins RJ, Gilles MK, Wang H, Jungwirth P, Laskin A. Internal structure, hygroscopic and reactive properties of mixed sodium methanesulfonate-sodium chloride particles. Physical Chemistry Chemical Physics : Pccp. 13: 11846-57. PMID 21573304 DOI: 10.1039/c1cp20444k  0.64
2011 Mayorov AV, Cai M, Palmer ES, Tanaka DK, Cain JP, Dedek MM, Tan B, Trivedi D, Hruby VJ. Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 21: 3099-102. PMID 21486697 DOI: 10.1016/j.bmcl.2011.03.019  0.88
2011 Hruby VJ, Cai M, Cain J, Nyberg J, Trivedi D. Design of novel melanocortin receptor ligands: multiple receptors, complex pharmacology, the challenge. European Journal of Pharmacology. 660: 88-93. PMID 21208601 DOI: 10.1016/j.ejphar.2010.10.109  0.88
2010 Mayorov AV, Cai M, Palmer ES, Liu Z, Cain JP, Vagner J, Trivedi D, Hruby VJ. Solid-phase peptide head-to-side chain cyclodimerization: discovery of C(2)-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptors. Peptides. 31: 1894-905. PMID 20688117 DOI: 10.1016/j.peptides.2010.06.026  0.88
2009 Guo D, Nichol GS, Cain JP, Yalkowsky SH. 2-[N-(2,4-Difluoro-phen-yl)carbamo-yl]-3,4,5,6-tetra-fluoro-benzoic acid. Acta Crystallographica. Section E, Structure Reports Online. 65: o2644. PMID 21578258 DOI: 10.1107/S1600536809038306  0.88
2008 Mayorov AV, Cai M, Palmer ES, Dedek MM, Cain JP, Van Scoy AR, Tan B, Vagner J, Trivedi D, Hruby VJ. Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptor. Journal of Medicinal Chemistry. 51: 187-95. PMID 18088090 DOI: 10.1021/jm070461w  0.88
2008 Lee YS, Agnes RS, Cain JP, Kulkarni V, Cai M, Salibay C, Ciano K, Petrov R, Mayorov A, Vagner J, Trivedi D, Davis P, Ma SW, Lai J, Porreca F, et al. Opioid and melanocortin receptors: do they have overlapping pharmacophores? Biopolymers. 90: 433-8. PMID 17657709 DOI: 10.1002/bip.20814  0.88
2007 Hruby VJ, Cai M, Cain JP, Mayorov AV, Dedek MM, Trivedi D. Design, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptor. Current Topics in Medicinal Chemistry. 7: 1107-19. PMID 17584128 DOI: 10.2174/156802607780906654  0.88
2006 Ndungu JM, Cain JP, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Synthesis of constrained analogues of cholecystokinin/opioid chimeric peptides. Tetrahedron Letters. 47: 2233-2236. PMID 17203138 DOI: 10.1016/j.tetlet.2006.01.096  0.88
2006 Cain JP, Mayorov AV, Cai M, Wang H, Tan B, Chandler K, Lee Y, Petrov RR, Trivedi D, Hruby VJ. Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5462-7. PMID 16931008 DOI: 10.1016/j.bmcl.2006.07.015  0.88
2005 Gu X, Ying J, Min B, Cain JP, Davis P, Willey P, Navratilova E, Yamamura HI, Porreca F, Hruby VJ. Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues. Biopolymers. 80: 151-63. PMID 15660379 DOI: 10.1002/bip.20208  0.88
2004 Cowell SM, Lee YS, Cain JP, Hruby VJ. Exploring Ramachandran and chi space: conformationally constrained amino acids and peptides in the design of bioactive polypeptide ligands. Current Medicinal Chemistry. 11: 2785-98. PMID 15544476  0.88
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