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Brian B. Liau, Ph.D. - Publications

Affiliations: 
2013 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Organic synthesis
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ngan KC, Hoenig SM, Kwok HS, Lue NZ, Gosavi PM, Tanner DA, Garcia EM, Lee C, Liau BB. Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. Elife. 12. PMID 36762644 DOI: 10.7554/eLife.80640  0.72
2023 Najm FJ, DeWeirdt P, Moore MM, Bevill SM, El Farran CA, Macias KA, Hegde M, Waterbury AL, Liau BB, van Galen P, Doench JG, Bernstein BE. Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature Communications. 14: 448. PMID 36707513 DOI: 10.1038/s41467-023-36150-7  0.519
2022 Gosavi PM, Ngan KC, Yeo MJR, Su C, Li J, Lue NZ, Hoenig SM, Liau BB. Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders. Acs Central Science. 8: 417-429. PMID 35505873 DOI: 10.1021/acscentsci.1c01603  0.714
2020 Kato S, Weng QY, Insco ML, Chen KY, Muralidhar S, Pozniak J, Diaz JMS, Drier Y, Nguyen N, Lo JA, van Rooijen E, Kemeny LV, Zhan Y, Feng Y, Silkworth W, ... ... Liau BB, et al. Gain-of-function genetic alterations of G9a drive oncogenesis. Cancer Discovery. PMID 32269030 DOI: 10.1158/2159-8290.Cd-19-0532  0.535
2019 Siegenfeld AP, Lee C, Liau BB. Taking a STAP at Core Promoter-Transcriptional Cofactor Specificity. Biochemistry. PMID 31298845 DOI: 10.1021/Acs.Biochem.9B00537  0.322
2019 Vinyard ME, Su C, Siegenfeld AP, Waterbury AL, Freedy AM, Gosavi PM, Park Y, Kwan EE, Senzer BD, Doench JG, Bauer DE, Pinello L, Liau BB. CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nature Chemical Biology. 15: 529-539. PMID 30992567 DOI: 10.1038/S41589-019-0263-0  0.732
2019 Park Y, Koga Y, Su C, Waterbury A, Johnny C, Liau B. A Versatile Synthetic Route to Cycloheximide and Analogues that Potently Inhibit Translation Elongation. Angewandte Chemie (International Ed. in English). PMID 30802354 DOI: 10.1002/Anie.201901386  0.344
2017 Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, et al. Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. PMID 28678782 DOI: 10.1038/Nature23000  0.572
2017 Miller TE, Liau B, Wallace LC, Morton A, Xie Q, Dixit D, Factor D, Kim L, Morrow J, Wu Q, Mack S, Hubert C, Paddison PJ, Horbinski C, Bernstein B, et al. GENE-30. TRANSCRIPTION ELONGATION FACTORS REPRESENT IN VIVO CANCER DEPENDENCIES IN GLIOBLASTOMA Neuro-Oncology. 19: vi99-vi99. DOI: 10.1093/Neuonc/Nox168.404  0.542
2016 Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, et al. Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell. PMID 27989769 DOI: 10.1016/J.Stem.2016.11.003  0.567
2016 Xie Q, Wu Q, Kim L, Miller TE, Liau BB, Mack SC, Yang K, Factor DC, Fang X, Huang Z, Zhou W, Alazem K, Wang X, Bernstein BE, Bao S, et al. RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation. The Journal of Clinical Investigation. PMID 27322055 DOI: 10.1172/Jci86114  0.584
2016 Flavahan W, Drier Y, Tarjan D, Liau B, Gillespie S, Venteicher A, Stemmer-Rachamimov A, Suva M, Bernstein B. GENT-19. INSULATOR DYSFUNCTION AS AN ONCOGENIC DRIVER IN GLIOMA Neuro-Oncology. 18: vi77-vi77. DOI: 10.1093/Neuonc/Now212.325  0.483
2015 Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. PMID 26700815 DOI: 10.1038/Nature16490  0.578
2015 van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE. A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Molecular Cell. PMID 26687680 DOI: 10.1016/J.Molcel.2015.11.003  0.557
2015 Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 526: 273-6. PMID 26416749 DOI: 10.1038/Nature14904  0.67
2015 van Galen P, Viny AD, Ram O, Ryan RJH, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE. A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes Molecular Cell. DOI: 10.1016/j.molcel.2015.11.003  0.458
2014 Lee AS, Liau BB, Shair MD. A unified strategy for the synthesis of 7-membered-ring-containing Lycopodium alkaloids. Journal of the American Chemical Society. 136: 13442-52. PMID 25152067 DOI: 10.1021/Ja507740U  0.644
2012 Liau BB, Milgram BC, Shair MD. Total syntheses of HMP-Y1, hibarimicinone, and HMP-P1. Journal of the American Chemical Society. 134: 16765-72. PMID 22970979 DOI: 10.1021/Ja307207Q  0.683
2011 Milgram BC, Liau BB, Shair MD. Gram-scale synthesis of the A'B'-subunit of angelmicin B. Organic Letters. 13: 6436-9. PMID 22084899 DOI: 10.1021/Ol202728V  0.68
2010 Liau BB, Shair MD. Total synthesis of (+)-fastigiatine. Journal of the American Chemical Society. 132: 9594-5. PMID 20568766 DOI: 10.1021/Ja104575H  0.616
2008 Liau BB, Gnanadesikan V, Corey EJ. A study of the effect of Z- and E-olefinic geometry on the rates of ring closure of 13-membered dienes. Organic Letters. 10: 1055-7. PMID 18275205 DOI: 10.1021/Ol702868Z  0.376
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