Brian A. Sparling, Ph.D. - Related publications

2013 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Organic synthesis
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Wang Z, Martin SF. Total Syntheses of (±)-Melicolones A and B. Organic Letters. PMID 33136416 DOI: 10.1021/acs.orglett.0c03454   
2020 Zhang R, Li Q, Zhang M, Chai S, Duan Y, Su J, Zhao Q, Zhang C. Copper and palladium co-catalyzed highly regio-selective 1,2-hydroarylation of terminal 1,3-dienes. Chemical Communications (Cambridge, England). PMID 33048065 DOI: 10.1039/d0cc06007k   
2020 Teo WJ, Yang X, Poon YY, Ge S. Cobalt-catalyzed deoxygenative triborylation of allylic ethers to access 1,1,3-triborylalkanes. Nature Communications. 11: 5193. PMID 33060600 DOI: 10.1038/s41467-020-19039-7   
2020 Wang Y, Du DM. Highly Diastereo- and Enantioselective Synthesis of Isoxazolone-Spirooxindoles via Squaramide-Catalyzed Cascade Michael/Michael Addition Reactions. The Journal of Organic Chemistry. PMID 33141592 DOI: 10.1021/acs.joc.0c02150   
2020 Pradhan S, Chauhan N, Shahi CK, Bhattacharyya A, Ghorai MK. Stereoselective Synthesis of Hexahydroimidazo[1,2-]quinolines via S2-Type Ring-Opening Hydroarylation-Hydroamination Cascade Cyclization of Activated Aziridines with -Propargylanilines. Organic Letters. PMID 32985195 DOI: 10.1021/acs.orglett.0c02801   
2020 Trost BM, Jiao Z, Liu Y, Min C, Hung CJ. Palladium-Catalyzed Enantioselective Cycloadditions of Aliphatic 1,4-Dipoles: Access to Chiral Cyclohexanes and Spiro [2.4] heptanes. Journal of the American Chemical Society. PMID 33052687 DOI: 10.1021/jacs.0c08348   
2020 Guo LD, Chen Y, Xu J. Total Synthesis of Alkaloids: From Bicycles to Diversified Caged Structures. Accounts of Chemical Research. PMID 33074659 DOI: 10.1021/acs.accounts.0c00532   
2020 Zhang C, Liang Z, Jia X, Wang M, Zhang G, Hu ML. A practical base mediated synthesis of 1,2,4-triazoles enabled by a deamination annulation strategy. Chemical Communications (Cambridge, England). PMID 33112300 DOI: 10.1039/d0cc05828a   
2020 Kumar RS, M Al-Thamili D, Almansour AI, Arumugam N, Dege N. [Bmim]Br Accelerated One-Pot Three-Component Cascade Protocol for the Construction of Spirooxindole-Pyrrolidine Heterocyclic Hybrids. Molecules (Basel, Switzerland). 25. PMID 33080968 DOI: 10.3390/molecules25204779   
2020 Li M, Wang T, An Z, Yan R. B(CF)-Catalyzed cyclization of alkynes: direct synthesis of 3-silyl heterocyclic compounds. Chemical Communications (Cambridge, England). 56: 11953-11956. PMID 33033821 DOI: 10.1039/d0cc04314a   
2020 Liu X, Yang J, Gao L, Zhang L, Lei X. Chemoenzymatic Total Syntheses of Artonin I with an Intermolecular Diels-Alderase. Biotechnology Journal. e2000119. PMID 33002294 DOI: 10.1002/biot.202000119   
2020 Geng X, Liu S, Wang W, Qu J, Wang B. -Amino Effect-Promoted Rearrangement of Aryl Isothiocyanate: A Versatile Approach to Benzimidazothiazepines and Benzimidazothioethers. The Journal of Organic Chemistry. 85: 12635-12643. PMID 32875799 DOI: 10.1021/acs.joc.0c01806   
2020 Zhang H, Zhang GM, He S, Shi ZC, Zhang XM, Wang JY. A Construction of α-Alkenyl Lactones via Reduction Radical Cascade Reaction of Allyl Alcohols and Acetylenic Acids. Organic Letters. PMID 33040535 DOI: 10.1021/acs.orglett.0c02973   
2020 Popik O, Grzeszczyk B, Staszewska-Krajewska O, Furman B, Chmielewski M. Synthesis of β-lactams via diastereoselective, intramolecular Kinugasa reactions. Organic & Biomolecular Chemistry. 18: 2852-2860. PMID 32211731 DOI: 10.1039/d0ob00228c   
2020 Li Y, Wang C, Ma Z, Zhang K, Xu XT. Asymmetric Total Synthesis and Assignment of Absolute Configuration of Arbornamine. Organic Letters. PMID 33104370 DOI: 10.1021/acs.orglett.0c03183   
2020 Breit B, Schmidt J. Rhodium-Catalyzed Cyclisation of Terminal and Internal Allenols: An Atom Economic and Highly Stereoselective Access Towards Tetrahydropyrans Johannes P. Schmidt, Bernhard Breit. Angewandte Chemie (International Ed. in English). PMID 32940396 DOI: 10.1002/anie.202009166   
2020 Gayyur, Choudhary S, Saxena A, Ghosh N. Gold-catalyzed homo- and cross-annulation of alkynyl carboxylic acids: a facile access to substituted 4-hydroxy 2-pyrones and total synthesis of pseudopyronine A. Organic & Biomolecular Chemistry. PMID 33089263 DOI: 10.1039/d0ob01700k   
2020 Wang Y, Tang K, Liu Z, Ning Y. Disulfonation of terminal alkynes for 1,2-bisulfonylethenes. Chemical Communications (Cambridge, England). PMID 33006590 DOI: 10.1039/d0cc05849a   
2020 Ruch M, Brach N, Galéa R, Wagner P, Blond G. Gold(I)-Catalyzed Domino Reaction for Furopyrans Synthesis. Molecules (Basel, Switzerland). 25. PMID 33121149 DOI: 10.3390/molecules25214976   
2020 Bauer A, Borsos E, Maulide N. A Novel Class of 7-Membered Heterocyclic Compounds. European Journal of Organic Chemistry. 2020: 3971-3974. PMID 32982576 DOI: 10.1002/ejoc.202000363   
2020 Zhao Z, Zhang Y, Shao Y, Xiong W, Li R, Chen J. Synthesis of 3-Selenylindoles through Organoselenium-Promoted Selenocyclization of 2-Vinylaniline. The Journal of Organic Chemistry. PMID 33152246 DOI: 10.1021/acs.joc.0c01918   
2020 Huang G, Kouklovsky C, de la Torre A. Inverse-Electron-Demand Diels-Alder Reactions of 2-Pyrones: Bridged Lactones and Beyond. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33085124 DOI: 10.1002/chem.202003980   
2020 Fedorova DD, Nazarova DS, Avetyan DL, Shatskiy A, Belyanin ML, Kärkäs MD, Stepanova EV. Divergent Synthesis of Natural Benzyl Salicylate and Benzyl Gentisate Glucosides. Journal of Natural Products. PMID 33008263 DOI: 10.1021/acs.jnatprod.0c00838   
2020 Ge J, Ding Q, Yang M, He T, Peng Y. Copper and manganese co-mediated cascade aza-Michael addition/cyclization and azidation of 1,3-enynes: regioselective synthesis of fully substituted azido pyrroles. Organic & Biomolecular Chemistry. PMID 33112335 DOI: 10.1039/d0ob01927e   
2020 Zahara AJ, Hinds EM, Nguyen AL, Wilkerson-Hill SM. Programmed Sequential Additions to Halogenated Mucononitriles. Organic Letters. PMID 33021798 DOI: 10.1021/acs.orglett.0c03007   
2020 O'Byrne SN, Eduful BJ, Willson TM, Drewry DH. Concise, gram-scale synthesis of furo[2,3-]pyridines with functional handles for chemoselective cross-coupling. Tetrahedron Letters. 61. PMID 33012852 DOI: 10.1016/j.tetlet.2020.152353   
2020 Li X, Mai S, Li X, Xu J, Xu H, Song Q. Cu-Catalyzed -Amino Benzofuranthioether Formation from -Tosylhydrazone-Bearing Thiocarbamates and Arylative Electrophiles. Organic Letters. PMID 32990445 DOI: 10.1021/acs.orglett.0c02778   
2020 Wang RB, Ren XD, He J, Zhu SS, Xie HR, Su GZ, Ma SG, Yu SS. Burchellin and its stereoisomers: total synthesis, structural elucidation and antiviral activity. Organic & Biomolecular Chemistry. PMID 33141138 DOI: 10.1039/d0ob01889a   
2020 Paixão MW, de Souza W, Matsuo B, Matos P, Correia JTMC, Santos MS, König B. Photocatalyzed Intramolecular [2+2] Cycloaddition of N-alkyl-N-(2-(1-arylvinyl)aryl)cinnamamides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32955792 DOI: 10.1002/chem.202003641   
2020 Yadav J, Pawar AP, Nagare YK, Iype E, Rangan K, Ohshita J, Kumar D, Kumar I. Direct Amine-Catalyzed Enantioselective Synthesis of Pentacyclic Dibenzo[,][1,4]oxazepine/Thiazepine-Fused Isoquinuclidines along with DFT Calculations. The Journal of Organic Chemistry. PMID 33030896 DOI: 10.1021/acs.joc.0c02141   
2020 Kumar GS, Lin Q. Light-Triggered Click Chemistry. Chemical Reviews. PMID 33104332 DOI: 10.1021/acs.chemrev.0c00799   
2020 Torelli A, Whyte A, Polishchuk I, Bajohr J, Lautens M. Stereoselective Construction of γ-Lactams via Copper-Catalyzed Borylacylation. Organic Letters. PMID 32991189 DOI: 10.1021/acs.orglett.0c02837   
2020 Debnath S, Das T, Pati TK, Majumdar S, Maiti DK. Metal-Free Indole-Phenacyl Bromide Cyclization: A Regioselective Synthesis of 3,5-Diarylcarbazoles. The Journal of Organic Chemistry. PMID 33006280 DOI: 10.1021/acs.joc.0c01670   
2020 Debnath S, Das T, Pati TK, Majumdar S, Maiti DK. Metal-Free Indole-Phenacyl Bromide Cyclization: A Regioselective Synthesis of 3,5-Diarylcarbazoles. The Journal of Organic Chemistry. PMID 33006280 DOI: 10.1021/acs.joc.0c01670   
2020 Bao X, Ren J, Yang Y, Ye X, Wang B, Wang H. 2-Activated 1,3-enynes in enantioselective synthesis. Organic & Biomolecular Chemistry. PMID 32996970 DOI: 10.1039/d0ob01614d   
2020 Zhou Y, Zhao P, Yu XX, Geng X, Wang C, Huang C, Yang H, Zhao ZY, Wu AX. Radical Tandem Bicyclization Triggered by the α-Position of α,β-Unsaturated Ketones Bearing Nonterminal 1,6-Enynes: Synthesis of the 5-Benzo[]fluoren-5-one Skeleton. Organic Letters. PMID 33040530 DOI: 10.1021/acs.orglett.0c02990   
2020 Knutson DE, Roni R, Mian Y, Cook JM, Stafford DC, Arnold LA. Improved scale-up synthesis and purification of clinical asthma candidate MIDD0301. Organic Process Research & Development. 24: 1467-1476. PMID 32952391 DOI: 10.1021/acs.oprd.0c00200   
2020 Yoon JA, Lim C, Han YT. Preliminary Study on Novel Expedient Synthesis of 5-Azaisocoumarins by Transition Metal-Catalyzed Cycloisomerization. Frontiers in Chemistry. 8: 772. PMID 33102431 DOI: 10.3389/fchem.2020.00772   
2020 Chen M, Liang Y, Dong T, Liang W, Liu Y, Zhang Y, Huang X, Kong L, Wang ZX, Peng B. Z-Selective  α-Arylation of α,β-Unsaturated Nitriles via [3,3]-Sigmatropic Rearrangement. Angewandte Chemie (International Ed. in English). PMID 33017503 DOI: 10.1002/anie.202010740   
2020 Li XR, Chen SQ, Fan J, Li CJ, Wang X, Liu ZW, Shi XY. Controllable Tandem [3+2] Cyclization of Aromatic Aldehydes with Maleimides: Rhodium(III)-Catalyzed Divergent Synthesis of Indane-Fused Pyrrolidine-2,5-dione. Organic Letters. PMID 33151078 DOI: 10.1021/acs.orglett.0c03113   
2020 Schneider T, Keim M, Seitz B, Maas G. Reactions of 3-aryl-1-(trifluoromethyl)prop-2-yn-1-iminium salts with 1,3-dienes and styrenes. Beilstein Journal of Organic Chemistry. 16: 2064-2072. PMID 32952722 DOI: 10.3762/bjoc.16.173   
2020 Kos M, Žádný J, Storch J, Církva V, Cuřínová P, Sýkora J, Císařová I, Kuriakose F, Alabugin IV. Oxidative Photocyclization of Aromatic Schiff Bases in Synthesis of Phenanthridines and Other Aza-PAHs. International Journal of Molecular Sciences. 21. PMID 32824231 DOI: 10.3390/ijms21165868   
2020 Grimm C, Lazzarotto M, Pompei S, Schichler J, Richter N, Farnberger JE, Fuchs M, Kroutil W. Oxygen-Free Regioselective Biocatalytic Demethylation of Methyl-phenyl Ethers via Methyltransfer Employing Veratrol--demethylase. Acs Catalysis. 10: 10375-10380. PMID 32974079 DOI: 10.1021/acscatal.0c02790   
2020 Chen J, Liu S, Lv X, Hong K, Lei J, Xu X, Hu W. Blue Light-Promoted Formal [4+1]-Annulation of Diazoacetates with -Aminoacetophenones: Synthesis of Polysubstituted Indolines and Computational Study. The Journal of Organic Chemistry. PMID 33034191 DOI: 10.1021/acs.joc.0c01974   
2020 Braasch-Turi M, Crans DC. Synthesis of Naphthoquinone Derivatives: Menaquinones, Lipoquinones and Other Vitamin K Derivatives. Molecules (Basel, Switzerland). 25. PMID 33003459 DOI: 10.3390/molecules25194477   
2020 Kardile RD, Liu RS. Gold(I)-Catalyzed Reactions between 2-(1-Alkynyl)-2-alken-1-ones and Vinyldiazo Ketones for Divergent Synthesis of Nonsymmetric Heteroaryl-Substituted Triarylmethanes: versus -Attack Paths. Organic Letters. PMID 33043671 DOI: 10.1021/acs.orglett.0c02765   
2020 Pound SM, Underwood SJ, Douglas CJ. Studies towards the total synthesis of drimentine C. Preparation of the AB and CDEF ring fragments. European Journal of Organic Chemistry. 2020: 2448-2453. PMID 33071626 DOI: 10.1002/ejoc.202000158   
2020 Sun X, Gong M, Huang M, Li Y, Kim JK, Kovalev V, Shokova E, Wu Y. "One-Pot" Synthesis of γ-Pyrones from Aromatic Ketones/Heteroarenes and Carboxylic Acids. The Journal of Organic Chemistry. PMID 33147963 DOI: 10.1021/acs.joc.0c01924   
2020 Yamaoka Y, Nakayama T, Kawai S, Takasu K. Total Synthesis of (-)-Sigillin A: A Polychlorinated and Polyoxygenated Natural Product. Organic Letters. PMID 32935991 DOI: 10.1021/acs.orglett.0c02930   
2020 Batista GMF, de Castro PP, Dos Santos HF, de Oliveira KT, Amarante GW. Electron-Donor-Acceptor Complex-Enabled Flow Methodology for the Hydrotrifluoromethylation of Unsaturated β-Keto Esters. Organic Letters. PMID 33086786 DOI: 10.1021/acs.orglett.0c03187