John Albert Beutler, Ph.D. - Publications

1984- Molecular Targets Laboratory National Cancer Institute, Rockville, MD, United States 
natural products, cancer

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Beutler JA. Natural Products as a Foundation for Drug Discovery Current Protocols in Pharmacology. 86: e67. PMID 31539923 DOI: 10.1002/cpph.67  0.01
2019 Valdeira ASC, Darvishi E, Woldemichael GM, Beutler JA, Gustafson KR, Salvador JAR. Madecassic Acid Derivatives as Potential Anticancer Agents: Synthesis and Cytotoxic Evaluation. Journal of Natural Products. PMID 31343174 DOI: 10.1021/acs.jnatprod.8b00864  1
2019 Tosun F, Beutler JA, Ransom TT, Miski M. Anatolicin, a Highly Potent and Selective Cytotoxic Sesquiterpene Coumarin from the Root Extract of . Molecules (Basel, Switzerland). 24. PMID 30909537 DOI: 10.3390/molecules24061153  1
2018 Miller JT, Zhao H, Masaoka T, Varnado B, Cornejo Castro EM, Marshall VA, Kouhestani K, Lynn AY, Aron KE, Xia A, Beutler JA, Hirsch DR, Tang L, Whitby D, Murelli RP, et al. Sensitivity of the C-terminal nuclease domain of Kaposi's sarcoma-associated herpesvirus ORF29 to two classes of active site ligands. Antimicrobial Agents and Chemotherapy. PMID 30061278 DOI: 10.1128/AAC.00233-18  1
2018 Espindola LS, Dusi RG, Demarque DP, Braz-Filho R, Yan P, Bokesch HR, Gustafson KR, Beutler JA. Cytotoxic Triterpenes from and Metabolite Profiling of Celastraceae Species. Molecules (Basel, Switzerland). 23. PMID 29925807 DOI: 10.3390/molecules23061494  1
2018 Rubaiy HN, Ludlow MJ, Siems K, Norman K, Foster R, Wolf D, Beutler JA, Beech DJ. Tonantzitlolone is a Nanomolar Potency Activator of TRPC1/4/5 Channels. British Journal of Pharmacology. PMID 29859013 DOI: 10.1111/bph.14379  1
2018 Hirsch DR, Schiavone DV, Berkowitz AJ, Morrison LA, Masaoka T, Wilson JA, Lomonosova E, Zhao H, Patel BS, Datla SH, Hoft SG, Majidi SJ, Pal RK, Gallicchio E, Tang L,Tavis JE, ... ... Beutler JA, et al. Synthesis and biological assessment of 3,7-dihydroxytropolones Org Biomol Chem. 16: 62-69. PMID 29098212 DOI: 10.1039/c7ob02453c  1
2017 Jia L, Lin H, Oppenheim J, Howard OMZ, Li J, Fan H, Zhao Z, Farrar W, Zhang Y, Colburn N, Young M, Li W, Newman D, O'Keefe BR, Beutler J,. Liu J, et al. U.S. National Cancer Institute - China collaborative studies on Chinese medicine and cancer J Natl Cancer Inst Monographs. lgx007. PMID 29140488 DOI: 10.1093/jncimonographs/lgx007  1
2017 Stockdale DP, Beutler JA, Wiemer DF. Synthesis of amide isosteres of schweinfurthin-based stilbenes. Bioorganic & Medicinal Chemistry. PMID 28866376 DOI: 10.1016/j.bmc.2017.08.016  1
2017 Elliott DC, Beutler JA, Parker KA. Importance of a 4-Alkyl Substituent for Activity in the Englerin Series. Acs Medicinal Chemistry Letters. 8: 746-750. PMID 28740610 DOI: 10.1021/acsmedchemlett.7b00161  0.04
2017 Cho N, Ransom TT, Sigmund J, Tran T, Cichewicz RH, Goetz M, Beutler JA. Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium Species. Journal of Natural Products. PMID 28654255 DOI: 10.1021/acs.jnatprod.7b00170  1
2017 da Cunha MG, Ramos-Junior ES, Franchin M, Taira TM, Beutler JA, Franco GCN, Ikegaki M, de Alencar SM, Fukada SY, Rosalen PL. Effects of Cinnamoyloxy-mammeisin from Geopropolis on Osteoclast Differentiation and Porphyromonas gingivalis-Induced Periodontitis. Journal of Natural Products. PMID 28570825 DOI: 10.1021/acs.jnatprod.7b00194  1
2017 Wu Z, Zhao S, Fash DM, Li Z, Chain WJ, Beutler JA. Englerins: A Comprehensive Review. Journal of Natural Products. PMID 28170253 DOI: 10.1021/acs.jnatprod.6b01167  1
2016 Murelli RP, D'Erasmo MP, Hirsch DR, Meck C, Masaoka T, Wilson JA, Zhang B, Pal RK, Gallicchio E, Beutler JA, Le Grice SF. Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity. Medchemcomm. 7: 1783-1788. PMID 28093576 DOI: 10.1039/C6MD00238B  1
2016 D'Erasmo MP, Masaoka T, Wilson JA, Hunte EM, Beutler JA, Le Grice SF, Murelli RP. Traceless Solid-Phase α-Hydroxytropolone Synthesis. Medchemcomm. 7: 1789-1792. PMID 28090282 DOI: 10.1039/C6MD00237D  1
2016 da Cunha MG, Franco GC, Franchin M, Beutler JA, de Alencar SM, Ikegaki M, Rosalen PL. Prediction of pharmacokinetic and toxicological parameters of a 4-phenylcoumarin isolated from geopropolis: in silico and in vitro approaches. Toxicology Letters. PMID 27773722 DOI: 10.1016/j.toxlet.2016.10.010  1
2016 Franchin M, Rosalen PL, da Cunha MG, Silva RL, Colón DF, Bassi GS, de Alencar SM, Ikegaki M, Alves-Filho JC, Cunha FQ, Beutler JA, Cunha TM. Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB. Journal of Natural Products. PMID 27367493 DOI: 10.1021/acs.jnatprod.6b00263  1
2016 Cho N, Kim HW, Kim TB, Ransom TT, Beutler JA, Sung SH. Preparative Purification of Anti-Proliferative Diarylheptanoids from Betula platyphylla by High-Speed Counter-Current Chromatography. Molecules (Basel, Switzerland). 21. PMID 27240338 DOI: 10.3390/molecules21060700  1
2016 Fash DM, Peer CJ, Li Z, Talisman IJ, Hayavi S, Sulzmaier FJ, Ramos JW, Sourbier C, Neckers L, Figg WD, Beutler JA, Chain WJ. Synthesis of a stable and orally bioavailable englerin analogue. Bioorganic & Medicinal Chemistry Letters. PMID 27107948 DOI: 10.1016/j.bmcl.2016.04.016  1
2016 Cho N, Moon EH, Kim HW, Hong J, Beutler JA, Sung SH. Inhibition of Nitric Oxide Production in BV2 Microglial Cells by Triterpenes from Tetrapanax papyriferus. Molecules (Basel, Switzerland). 21. PMID 27070561 DOI: 10.3390/molecules21040459  1
2016 Yeo D, Huynh N, Beutler JA, Baldwin GS, He H, Nikfarjam M. Glaucarubinone Combined with Gemcitabine Improves Pancreatic Cancer Survival in an Immunocompetent Orthotopic Murine Model. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 1-7. PMID 27027695 DOI: 10.3109/08941939.2016.1160167  1
2016 López-Suárez L, Riesgo L, Bravo F, Ransom TT, Beutler JA, Echavarren AM. Synthesis and Biological Evaluation of New (-)-Englerin Analogues. Chemmedchem. PMID 27005578 DOI: 10.1002/cmdc.201600040  1
2016 Masaoka T, Zhao H, Hirsch DR, D'Erasmo MP, Meck C, Varnado B, Gupta A, Meyers MJ, Baines J, Beutler JA, Murelli RP, Tang L, Le Grice SF. Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors. Biochemistry. PMID 26829613 DOI: 10.1021/acs.biochem.5b01254  1
2016 da Cunha MG, Franchin M, de Paula-Eduardo LF, Freires IA, Beutler JA, de Alencar SM, Ikegaki M, Tabchoury CPM, Cunha TM, Rosalen PL. Anti-inflammatory and anti-biofilm properties of ent-nemorosone from Brazilian geopropolis J Funct Foods. 26: 27-35. DOI: 10.1016/j.jff.2016.07.009  1
2015 Qin T, Iwata T, Ransom TT, Beutler JA, Porco JA. Syntheses of Dimeric Tetrahydroxanthones with Varied Linkages: Investigation of "Shapeshifting" Properties. Journal of the American Chemical Society. PMID 26544765 DOI: 10.1021/jacs.5b09825  1
2015 da Cunha MG, Rosalen PL, Franchin M, de Alencar SM, Ikegaki M, Ransom T, Beutler JA. Antiproliferative Constituents of Geopropolis from the Bee Melipona scutellaris. Planta Medica. PMID 26544117 DOI: 10.1055/s-0035-1558142  1
2015 Zhao H, Lin Z, Lynn AY, Varnado B, Beutler JA, Murelli RP, Le Grice SF, Tang L. Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism. Nucleic Acids Research. PMID 26450964 DOI: 10.1093/nar/gkv1018  1
2015 Sourbier C, Scroggins BT, Mannes PZ, Liao PJ, Siems K, Wolf D, Beutler JA, Linehan WM, Neckers L. Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent. Oncotarget. 6: 29963-74. PMID 26298773 DOI: 10.18632/oncotarget.4676  1
2015 Ma J, Pawar RS, Grundel E, Mazzola EP, Ridge CD, Masaoka T, Le Grice SF, Wilson J, Beutler JA, Krynitsky AJ. Sesquiterpenoid tropolone glycosides from Liriosma ovata. Journal of Natural Products. 78: 315-9. PMID 25587934 DOI: 10.1021/np5006696  1
2015 Huynh N, Beutler JA, Shulkes A, Baldwin GS, He H. Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1α and β-catenin via a p-21 activated kinase 1-dependent pathway. Biochimica Et Biophysica Acta. 1853: 157-65. PMID 25409929 DOI: 10.1016/j.bbamcr.2014.10.013  1
2014 Sunassee SN, Ransom T, Henrich CJ, Beutler JA, Covell DG, McMahon JB, Gustafson KR. Steroidal alkaloids from the marine sponge Corticium niger that inhibit growth of human colon carcinoma cells. Journal of Natural Products. 77: 2475-80. PMID 25338277 DOI: 10.1021/np500556t  1
2014 Kodet JG, Beutler JA, Wiemer DF. Synthesis and structure activity relationships of schweinfurthin indoles. Bioorganic & Medicinal Chemistry. 22: 2542-52. PMID 24656801 DOI: 10.1016/j.bmc.2014.02.043  1
2014 Lockett SJ, Cui C, Gudla P, Nandy K, Mimaki Y, Fuchs PL, Jaja J, Reilly KM, Beutler JA, Turbyville TJ. Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticals Cytometry Part A. 85: 512-521. PMID 24515854 DOI: 10.1002/cyto.a.22442  1
2014 Yeo D, Huynh N, Beutler JA, Christophi C, Shulkes A, Baldwin GS, Nikfarjam M, He H. Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases. Cancer Letters. 346: 264-72. PMID 24491405 DOI: 10.1016/j.canlet.2014.01.001  1
2014 Hartung AM, Beutler JA, Navarro HA, Wiemer DF, Neighbors JD. Stilbenes as κ-selective, non-nitrogenous opioid receptor antagonists. Journal of Natural Products. 77: 311-9. PMID 24456556 DOI: 10.1021/np4009046  1
2014 Devkota KP, Wilson JA, Henrich CJ, McMahon JB, Reilly KM, Beutler JA. Compounds from Simarouba berteroana which inhibit proliferation of NF1-defective cancer cells. Phytochemistry Letters. 7: 42-45. PMID 24443661 DOI: 10.1016/j.phytol.2013.09.007  1
2014 Beutler JA, Cragg GM, Iwu M, Newman DJ, Okunji C. Anticancer Potential of African Plants: The Experience of the United States National Cancer Institute and National Institutes of Health Chapter 10 in Novel Plant Bioresources: Applications in Food, Medicine and Cosmetics Editor: Gurib-Fakim A. 133-149. DOI: 10.1002/9781118460566_10  1
2013 Dossou KS, Devkota KP, Morton C, Egan JM, Lu G, Beutler JA, Moaddel R. Identification of CB1/CB2 ligands from Zanthoxylum bungeanum. Journal of Natural Products. 76: 2060-4. PMID 24175626 DOI: 10.1021/np400478c  1
2013 Henrich CJ, Beutler JA. Matching the power of high throughput screening to the chemical diversity of natural products. Natural Product Reports. 30: 1284-98. PMID 23925671 DOI: 10.1039/c3np70052f  1
2013 Kanduluru AK, Banerjee P, Beutler JA, Fuchs PL. A convergent total synthesis of the potent cephalostatin/ritterazine hybrid -25-epi ritterostatin GN1N. The Journal of Organic Chemistry. 78: 9085-92. PMID 23899273 DOI: 10.1021/jo401171q  1
2013 Winter DK, Endoma-Arias MA, Hudlicky T, Beutler JA, Porco JA. Enantioselective total synthesis and biological evaluation of (+)-kibdelone A and a tetrahydroxanthone analogue. The Journal of Organic Chemistry. 78: 7617-26. PMID 23834060 DOI: 10.1021/jo401169z  1
2013 Masaoka T, Chung S, Caboni P, Rausch JW, Wilson JA, Taskent-Sezgin H, Beutler JA, Tocco G, Le Grice SF. Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. Journal of Medicinal Chemistry. 56: 5436-45. PMID 23631411 DOI: 10.1021/jm400405z  1
2013 Devkota KP, Covell D, Ransom T, McMahon JB, Beutler JA. Growth inhibition of human colon carcinoma cells by sesquiterpenoids and tetralones of Zygogynum calothyrsum. Journal of Natural Products. 76: 710-4. PMID 23517126 DOI: 10.1021/np400042q  1
2013 Dossou KS, Devkota KP, Kavanagh PV, Beutler JA, Egan JM, Moaddel R. Development and preliminary validation of a plate-based CB1/CB2 receptor functional assay. Analytical Biochemistry. 437: 138-43. PMID 23481912 DOI: 10.1016/j.ab.2013.02.025  1
2013 Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, Linehan WM, Neckers L. Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell. 23: 228-37. PMID 23352416 DOI: 10.1016/j.ccr.2012.12.007  1
2013 Devkota KP, Wilson J, Henrich CJ, McMahon JB, Reilly KM, Beutler JA. Isobutylhydroxyamides from the pericarp of Nepalese Zanthoxylum armatum inhibit NF1-defective tumor cell line growth. Journal of Natural Products. 76: 59-63. PMID 23268719 DOI: 10.1021/np300696g  1
2013 Beutler JA. Natural Products as Tools for Discovering New Cancer Targets Chapter 9 in Natural Products and Cancer Drug Discovery Ed: Koehn F. 213-237. DOI: 10.1007/978-1-4614-4654-5_9  0.01
2012 Dong S, Qin T, Hamel E, Beutler JA, Porco JA. Synthesis of chamaecypanone C analogues from in situ-generated cyclopentadienones and their biological evaluation. Journal of the American Chemical Society. 134: 19782-7. PMID 23110297 DOI: 10.1021/ja3084708  1
2012 Diyabalanage T, Ratnayake R, Bokesch HR, Ransom TT, Henrich CJ, Beutler JA, McMahon JB, Gustafson KR. Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera. Journal of Natural Products. 75: 1490-4. PMID 22834941 DOI: 10.1021/np3003518  1
2012 Akee RK, Ransom T, Ratnayake R, McMahon JB, Beutler JA. Chlorinated englerins with selective inhibition of renal cancer cell growth. Journal of Natural Products. 75: 459-63. PMID 22280462 DOI: 10.1021/np200905u  1
2012 Beutler JA. Early years of the journal. Pharmaceutical Biology. 50: 6-7. PMID 22181341 DOI: 10.3109/13880209.2011.601315  0.01
2012 Beutler JA, Cragg GM, Newman DJ. The national cancer institute and natural product-based drug discovery in Africa Drug Discovery in Africa: Impacts of Genomics, Natural Products, Traditional Medicines, Insights Into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs. 2147483647: 29-52. DOI: 10.1007/978-3-642-28175-4_2  1
2011 Topczewski JJ, Callahan MP, Kodet JG, Inbarasu JD, Mente NR, Beutler JA, Wiemer DF. Relevance of the C-5 position to schweinfurthin induced cytotoxicity. Bioorganic & Medicinal Chemistry. 19: 7570-81. PMID 22055715 DOI: 10.1016/j.bmc.2011.10.034  1
2011 Dong S, Cahill KJ, Kang MI, Colburn NH, Henrich CJ, Wilson JA, Beutler JA, Johnson RP, Porco JA. Microwave-based reaction screening: tandem retro-Diels-Alder/Diels-Alder cycloadditions of o-quinol dimers. The Journal of Organic Chemistry. 76: 8944-54. PMID 21942286 DOI: 10.1021/jo201658y  1
2011 Zhao LX, Huang SX, Tang SK, Jiang CL, Duan Y, Beutler JA, Henrich CJ, McMahon JB, Schmid T, Blees JS, Colburn NH, Rajski SR, Shen B. Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. Journal of Natural Products. 74: 1990-5. PMID 21870828 DOI: 10.1021/np200603g  1
2011 Popplewell WL, Ratnayake R, Wilson JA, Beutler JA, Colburn NH, Henrich CJ, McMahon JB, McKee TC. Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula. Journal of Natural Products. 74: 1686-91. PMID 21806011 DOI: 10.1021/np2005083  1
2011 Diyabalanage T, Ratnayake R, Wilson JA, Henrich CJ, Beutler JA, Colburn NH, McMahon JB, Gustafson KR. Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorganic & Medicinal Chemistry Letters. 21: 4397-9. PMID 21733691 DOI: 10.1016/j.bmcl.2011.06.044  1
2011 Tai BH, Nhut ND, Nhiem NX, Quang TH, Thanh Ngan NT, Thuy Luyen BT, Huong TT, Wilson J, Beutler JA, Ban NK, Cuong NM, Kim YH. An evaluation of the RNase H inhibitory effects of Vietnamese medicinal plant extracts and natural compounds. Pharmaceutical Biology. 49: 1046-51. PMID 21595586 DOI: 10.3109/13880209.2011.563316  1
2011 Chung S, Himmel DM, Jiang JK, Wojtak K, Bauman JD, Rausch JW, Wilson JA, Beutler JA, Thomas CJ, Arnold E, Le Grice SF. Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. Journal of Medicinal Chemistry. 54: 4462-73. PMID 21568335 DOI: 10.1021/jm2000757  1
2011 Kim JA, Yang SY, Wamiru A, McMahon JB, Le Grice SF, Beutler JA, Kim YH. New monoterpene glycosides and phenolic compounds from Distylium racemosum and their inhibitory activity against ribonuclease H. Bioorganic & Medicinal Chemistry Letters. 21: 2840-4. PMID 21489793 DOI: 10.1016/j.bmcl.2011.03.091  1
2011 Sloman DL, Mitasev B, Scully SS, Beutler JA, Porco JA. Synthesis and biological evaluation of ABCD ring fragments of the kibdelones. Angewandte Chemie (International Ed. in English). 50: 2511-5. PMID 21370327 DOI: 10.1002/anie.201007613  1
2011 Devkota KP, Ratnayake R, Colburn NH, Wilson JA, Henrich CJ, McMahon JB, Beutler JA. Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius. Journal of Natural Products. 74: 374-7. PMID 21306129 DOI: 10.1021/np100736y  1
2011 Best AM, Chang J, Dull AB, Beutler JA, Martinez ED. Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay. Journal of Biomedicine & Biotechnology. 2011: 868095. PMID 21234371 DOI: 10.1155/2011/868095  1
2010 Suzuki S, Urano E, Hashimoto C, Tsutsumi H, Nakahara T, Tanaka T, Nakanishi Y, Maddali K, Han Y, Hamatake M, Miyauchi K, Pommier Y, Beutler JA, Sugiura W, Fuji H, et al. Peptide HIV-1 integrase inhibitors from HIV-1 gene products. Journal of Medicinal Chemistry. 53: 5356-60. PMID 20586421 DOI: 10.1021/jm1003528  1
2010 Chung S, Wendeler M, Rausch JW, Beilhartz G, Gotte M, O'Keefe BR, Bermingham A, Beutler JA, Liu S, Zhuang X, Le Grice SF. Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Antimicrobial Agents and Chemotherapy. 54: 3913-21. PMID 20547794 DOI: 10.1128/AAC.00434-10  1
2010 Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM. Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner. Molecular Cancer Therapeutics. 9: 1234-43. PMID 20442305 DOI: 10.1158/1535-7163.MCT-09-0834  1
2010 Ulrich NC, Kodet JG, Mente NR, Kuder CH, Beutler JA, Hohl RJ, Wiemer DF. Structural analogues of schweinfurthin F: probing the steric, electronic, and hydrophobic properties of the D-ring substructure. Bioorganic & Medicinal Chemistry. 18: 1676-83. PMID 20116262 DOI: 10.1016/j.bmc.2009.12.063  1
2010 Klausmeyer P, Van QN, Jato J, McCloud TG, Beutler JA. Schweinfurthins I and J from Macaranga schweinfurthii. Journal of Natural Products. 73: 479-81. PMID 20000454 DOI: 10.1021/np9006348  1
2009 Beutler JA. Natural Products as a Foundation for Drug Discovery. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 46: 9.11.1-9.11.21. PMID 20161632 DOI: 10.1002/0471141755.ph0911s46  0.01
2009 Beutler JA, Kang MI, Robert F, Clement JA, Pelletier J, Colburn NH, McKee TC, Goncharova E, McMahon JB, Henrich CJ. Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. Journal of Natural Products. 72: 503-6. PMID 19199792 DOI: 10.1021/np800732n  1
2009 Wrona IE, Lowe JT, Turbyville TJ, Johnson TR, Beignet J, Beutler JA, Panek JS. Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth. The Journal of Organic Chemistry. 74: 1897-916. PMID 19191575 DOI: 10.1021/jo802269q  1
2009 Dong S, Hamel E, Bai R, Covell DG, Beutler JA, Porco JA. Enantioselective synthesis of (+)-chamaecypanone C: a novel microtubule inhibitor. Angewandte Chemie (International Ed. in English). 48: 1494-7. PMID 19140149 DOI: 10.1002/anie.200805486  1
2009 Ratnayake R, Covell D, Ransom TT, Gustafson KR, Beutler JA. Englerin A, a selective inhibitor of renal cancer cell growth, from Phyllanthus engleri. Organic Letters. 11: 57-60. PMID 19061394 DOI: 10.1021/ol802339w  1
2009 Wendeler M, Beilhartz GL, Beutler JA, Götte M, Le Grice SFJ. HIV ribonuclease H: Continuing the search for small molecule antagonists Hiv Therapy. 3: 39-53. DOI: 10.2217/17584310.3.1.39  1
2009 eds: Cragg G, Beutler JA, Jones WP. The American Society of Pharmacognosy. 50 Years of Progress in Natural Progress Research. 1959-2009 0.01
2008 Weissman AM, Yang Y, Kitagaki J, Sasiela CA, Beutler JA, O'Keefe BR. Inhibiting Hdm2 and ubiquitin-activating enzyme: targeting the ubiquitin conjugating system in cancer. Ernst Schering Foundation Symposium Proceedings. 171-90. PMID 19202599  1
2008 Wendeler M, Lee H-F, Bermingham A, Miller JT, Chertov O, Bona MK, Baichoo NS, Ehteshami M, Beutler JA, O'Keefe BR, Götte M, Kvaratskhelia M, Le Grice SFJ. Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity Acs Chem Biol. 3: 635-644. PMID 18831589 DOI: 10.1021/cb8001039  1
2008 Bokesch HR, Wamiru A, Le Grice SF, Beutler JA, McKee TC, McMahon JB. HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis. Journal of Natural Products. 71: 1634-6. PMID 18763827 DOI: 10.1021/np8002518  1
2008 Sasiela CA, Stewart DH, Kitagaki J, Safiran YJ, Yang Y, Weissman AM, Oberoi P, Davydov IV, Goncharova E, Beutler JA, McMahon JB, O'Keefe BR. Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen. Journal of Biomolecular Screening. 13: 229-37. PMID 18270365 DOI: 10.1177/1087057108315038  1
2008 Marchand C, Beutler JA, Wamiru A, Budihas S, Möllmann U, Heinisch L, Mellors JW, Le Grice SF, Pommier Y. Madurahydroxylactone derivatives as dual inhibitors of human immunodeficiency virus type 1 integrase and RNase H. Antimicrobial Agents and Chemotherapy. 52: 361-4. PMID 17967911 DOI: 10.1128/AAC.00883-07  1
2007 Takada K, Bermingham A, O'Keefe BR, Wamiru A, Beutler JA, Le Grice SF, Lloyd J, Gustafson KR, McMahon JB. An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis. Journal of Natural Products. 70: 1647-9. PMID 17935297 DOI: 10.1021/np0702279  1
2007 Yang Y, Kitagaki J, Dai RM, Tsai YC, Lorick KL, Ludwig RL, Pierre SA, Jensen JP, Davydov IV, Oberoi P, Li CC, Kenten JH, Beutler JA, Vousden KH, Weissman AM. Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. Cancer Research. 67: 9472-81. PMID 17909057 DOI: 10.1158/0008-5472.CAN-07-0568  1
2007 Dat NT, Bae K, Wamiru A, McMahon JB, Le Grice SF, Bona M, Beutler JA, Kim YH. A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H. Journal of Natural Products. 70: 839-41. PMID 17397219 DOI: 10.1021/np060359m  1
2007 Mente NR, Wiemer AJ, Neighbors JD, Beutler JA, Hohl RJ, Wiemer DF. Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: differences of bioactivity in the enantiomeric series. Bioorganic & Medicinal Chemistry Letters. 17: 911-5. PMID 17236766 DOI: 10.1016/j.bmcl.2006.11.096  1
2006 Martinez ED, Dull AB, Beutler JA, Hager GL. High-content fluorescence-based screening for epigenetic modulators. Methods in Enzymology. 414: 21-36. PMID 17110184 DOI: 10.1016/S0076-6879(06)14002-1  1
2006 Kim YH, Park EJ, Park MH, Badarch U, Woldemichael GM, Beutler JA. Crinamine from Crinum asiaticum var. japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2. Biological & Pharmaceutical Bulletin. 29: 2140-2. PMID 17015967 DOI: JST.JSTAGE/bpb/29.2140  1
2006 Liang MC, Bardhan S, Pace EA, Rosman D, Beutler JA, Porco JA, Gilmore TD. Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. Biochemical Pharmacology. 71: 634-45. PMID 16360644 DOI: 10.1016/j.bcp.2005.11.013  1
2006 Neighbors JD, Salnikova MS, Beutler JA, Wiemer DF. Synthesis and structure-activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity. Bioorganic & Medicinal Chemistry. 14: 1771-84. PMID 16290161 DOI: 10.1016/j.bmc.2005.10.025  1
2006 Beutler JA, Jato J, Cragg GM, Wiemer DF, Neighbors JD, Salnikova MS, Hollingshead MG, Scudiero D, McCloud TG. The schweinfurthins: Issues in development of a plant-based anticancer lead Chapter 22 in: Medicinal and Aromatic Plants. Agricultural, Commercial, Ecological, Legal, Pharmacological and Social Aspects, Eds: Bogers Rj, Craker L, Lange D. 17. DOI: 10.1007/1-4020-5447-5_22  1
2005 Budihas SR, Gorshkova I, Gaidamakov S, Wamiru A, Bona MK, Parniak MA, Crouch RJ, McMahon JB, Beutler JA, Le Grice SF. Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Nucleic Acids Research. 33: 1249-56. PMID 15741178 DOI: 10.1093/nar/gki268  1
2005 Neighbors JD, Beutler JA, Wiemer DF. Synthesis of nonracemic 3-deoxyschweinfurthin B. The Journal of Organic Chemistry. 70: 925-31. PMID 15675850 DOI: 10.1021/jo048444r  1
2005 Çaliş I, Kirmizibekmez H, Beutler JA, Dönmez AA, Yalçin FN, Kiliç E, Özalp M, Rüedi P, Taşdemir D. Secondary metabolites of Phlomis viscosa and their biological activities Turkish Journal of Chemistry. 29: 71-81.  0.04
2004 Chan KC, Budihas SR, Le Grice SF, Parniak MA, Crouch RJ, Gaidamakov SA, Isaaq HJ, Wamiru A, McMahon JB, Beutler JA. A capillary electrophoretic assay for ribonuclease H activity. Analytical Biochemistry. 331: 296-302. PMID 15265735 DOI: 10.1016/j.ab.2004.05.017  1
2004 Bokesch HR, Charan RD, Meragelman KM, Beutler JA, Gardella R, O'Keefe BR, McKee TC, McMahon JB. Isolation and characterization of anti-HIV peptides from Dorstenia contrajerva and Treculia obovoidea. Febs Letters. 567: 287-90. PMID 15178338 DOI: 10.1016/j.febslet.2004.04.085  1
2003 Parniak MA, Min KL, Budihas SR, Le Grice SF, Beutler JA. A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity. Analytical Biochemistry. 322: 33-9. PMID 14705777 DOI: 10.1016/j.ab.2003.06.001  1
2003 Chen X, Beutler JA, McCloud TG, Loehfelm A, Yang L, Dong HF, Chertov OY, Salcedo R, Oppenheim JJ, Howard OM. Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3115-23. PMID 12912963  1
2003 Beutler JA, McKee TC. Novel marine and microbial natural product inhibitors of vacuolar ATPase. Current Medicinal Chemistry. 10: 787-96. PMID 12678782 DOI: 10.2174/0929867033457827  1
2002 Erickson KL, Gustafson KR, Pannell LK, Beutler JA, Boyd MR. New dimeric macrolide glycosides from the marine sponge Myriastra clavosa. Journal of Natural Products. 65: 1303-6. PMID 12350152 DOI: 10.1021/np020193z  1
2002 Beutler JA, McMahon JB, Johnson TR, O'Keefe BR, Buzzell RA, Robbins D, Gardella R, Wilson J, Boyd MR. High throughput screening for cyanovirin-N mimetics binding to HIV-1 gp41. Journal of Biomolecular Screening. 7: 105-10. PMID 12006108 DOI: 10.1089/10870570252906558  1
2001 Boyd MR, Farina C, Belfiore P, Gagliardi S, Kim JW, Hayakawa Y, Beutler JA, McKee TC, Bowman BJ, Bowman EJ. Discovery of a novel antitumor benzolactone enamide class that selectively inhibits mammalian vacuolar-type (H+)-atpases. The Journal of Pharmacology and Experimental Therapeutics. 297: 114-20. PMID 11259534  1
2001 Kuroda M, Mimaki Y, Yokosuka A, Sashida Y, Beutler JA. Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiae. Journal of Natural Products. 64: 88-91. PMID 11170674 DOI: 10.1021/np0003084  1
2000 Beutler JA, McCall KL, Herbert K, Johnson T, Shoemaker RH, Boyd MR. Cytotoxic clerodane diterpene esters from Laetia corymbulosa. Phytochemistry. 55: 233-6. PMID 11142848 DOI: 10.1016/S0031-9422(00)00281-8  1
2000 Davies-Coleman MT, Gustafson KR, Cantrell CL, Beutler JA, Pannell LK, Boyd MR. Stolonic acids A and B, new cytotoxic cyclic peroxides from an Indian Ocean ascidian Stolonica species. Journal of Natural Products. 63: 1411-3. PMID 11076564 DOI: 10.1021/np000158x  1
2000 Keskin O, Bahar I, Jernigan RL, Beutler JA, Shoemaker RH, Sausville EA, Covell DG. Characterization of anticancer agents by their growth inhibitory activity and relationships to mechanism of action and structure. Anti-Cancer Drug Design. 15: 79-98. PMID 10901296  1
2000 McMahon JB, Beutler JA, O'Keefe BR, Goodrum CB, Myers MA, Boyd MR. Development of a cyanovirin-N-HIV-1 gp120 binding assay for high throughput screening of natural product extracts by time-resolved fluorescence. Journal of Biomolecular Screening. 5: 169-76. PMID 10894760  1
2000 Beutler JA, McCall KL, Herbert K, Herald DL, Pettit GR, Johnson T, Shoemaker RH, Boyd MR. Novel cytotoxic diterpenes from Casearia arborea. Journal of Natural Products. 63: 657-61. PMID 10843580 DOI: 10.1021/np990553r  1
2000 Beutler JA, Jato J, Cragg GM, Boyd MR. Schweinfurthin D, a cytotoxic stilbene from Macaranga schweinfurthii Natural Product Letters. 14: 399-404.  1
1999 Beutler JA, McCall KL, Boyd MR. A novel geranylflavone from Macaranga schweinfurthii Natural Product Letters. 13: 29-32.  1
1998 Beutler JA, Shoemaker RH, Johnson T, Boyd MR. Cytotoxic geranyl stilbenes from Macaranga schweinfurthii. Journal of Natural Products. 61: 1509-12. PMID 9868152 DOI: 10.1021/np980208m  1
1998 O'Keefe BR, Erim T, Beutler JA, Cardellina JH, Gulakowski RJ, Krepps BL, McMahon JB, Sowder RC, Johnson DG, Buckheit RW, Halliday S, Boyd MR. Isolation and characterization of adociavirin, a novel HIV-inhibitory protein from the sponge Adocia sp. Febs Letters. 431: 85-90. PMID 9684871 DOI: 10.1016/S0014-5793(98)00736-4  1
1998 Beutler JA, Hamel E, Vlietinck AJ, Haemers A, Rajan P, Roitman JN, Cardellina JH, Boyd MR. Structure-activity requirements for flavone cytotoxicity and binding to tubulin. Journal of Medicinal Chemistry. 41: 2333-8. PMID 9632366 DOI: 10.1021/jm970842h  1
1997 Erickson KL, Beutler JA, Cardellina II JH, Boyd MR. Salicylihalamides A and B, Novel Cytotoxic Macrolides from the Marine Sponge Haliclona sp. The Journal of Organic Chemistry. 62: 8188-8192. PMID 11671930 DOI: 10.1021/jo971556g  1
1997 O'Keefe BR, Beutler JA, Cardellina JH, Prather TR, Shoemaker RH, Sowder RC, Henderson LE, Pannell LK, Boyd MR. Isolation of a novel Kunitz family protease inhibitor in association with Tethya hemolysin from the sponge Tethya ingalli. Journal of Natural Products. 60: 1094-9. PMID 9392878 DOI: 10.1021/np970242l  1
1997 Beutler JA, Kashman Y, Pannell LK, Cardellina JH, Alexander MR, Balaschak MS, Prather TR, Shoemaker RH, Boyd MR. Isolation and characterization of novel cytotoxic saponins from Archidendron ellipticum. Bioorganic & Medicinal Chemistry. 5: 1509-17. PMID 9313857 DOI: 10.1016/S0968-0896(97)00098-9  1
1997 O'Keefe BR, Beutler JA, Cardellina JH, Gulakowski RJ, Krepps BL, McMahon JB, Sowder RC, Henderson LE, Pannell LK, Pomponi SA, Boyd MR. Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta. European Journal of Biochemistry / Febs. 245: 47-53. PMID 9128723  1
1997 Mimaki Y, Kuroda M, Kameyama A, Sashida Y, Hirano T, Oka K, Maekawa R, Wada T, Sugita K, Beutler JA. Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs Bioorganic and Medicinal Chemistry Letters. 7: 633-636. DOI: 10.1016/S0960-894X(97)00071-1  1
1997 Beutler JA. Separations of high molecular weight saponins of Archidendron ellipticum by hydrophilic interaction chromatography Journal of Liquid Chromatography and Related Technologies. 20: 2415-2426.  0.01
1996 Beutler JA, Alvarado-Lindner AB, McCloud TG. Further studies on phorbol ester bioactivity in the Euphorbiaceae Annals of the Missouri Botanical Garden. 83: 530-533.  1
1995 Erickson KL, Beutler JA, Gray GN, Cardellina JH, Boyd MR. Majapolene A, a cytotoxic peroxide, and related sesquiterpenes from the red alga Laurencia majuscula. Journal of Natural Products. 58: 1848-60. PMID 8691206 DOI: 10.1021/np50126a007  1
1995 Erickson KL, Beutler JA, Cardellina JH, McMahon JB, Newman DJ, Boyd MR. A novel phorbol ester from Excoecaria agallocha. Journal of Natural Products. 58: 769-72. PMID 7623051  1
1995 Beutler JA, Kashman Y, Tischler M, Cardellina JH, Gray GN, Currens MJ, Wall ME, Wani MC, Boyd MR. A reinvestigation of Maprounea triterpenes. Journal of Natural Products. 58: 1039-46. PMID 7561897  1
1995 Erickson KL, Beutler JA, Cardellina JH, Boyd MR. Rottnestol, a new hemiketal from the sponge Haliclona sp. Tetrahedron. 51: 11953-11958. DOI: 10.1016/0040-4020(95)00761-V  1
1995 Beutler JA, Cardellina JH II, McMahon JB, Shoemaker RH, Boyd MR. Antiviral and antitumor plant metabolites Chapter 3 in: Phytochemistry of Medicinal Plants, Eds Arnason Jt, Romeo Jt. 47-64. DOI: 10.1007/0-306-45181-6_3  1
1994 Beutler JA, Clark P, Alvarado AB, Golik J. Esperamicin P, the tetrasulfide analog of esperamicin A1. Journal of Natural Products. 57: 629-33. PMID 8064295  1
1994 Cachau RE, Gussio R, Beutler JA, Chmurny GN, Hilton BD, Muschik GM, Erickson JW. Solution structure of taxol determined using a novel feedback-scaling procedure for nOe-restrained molecular dynamics Supercomputer Applications and High Performance Computing. 8: 24-34. DOI: 10.1177/109434209400800104  1
1993 Beutler JA, Cardellina JH, Prather T, Shoemaker RH, Boyd MR, Snader KM. A cytotoxic beta-carboline from the bryozoan Catenicella cribraria. Journal of Natural Products. 56: 1825-6. PMID 8277321  1
1993 Beutler JA, Cardellina JH, Gray GN, Prather TR, Shoemaker RH, Boyd MR, Lin CM, Hamel E, Cragg GM. Two new cytotoxic chalcones from Calythropsis aurea. Journal of Natural Products. 56: 1718-22. PMID 8277311  1
1993 Cardellina JH, Munro MH, Fuller RW, Manfredi KP, McKee TC, Tischler M, Bokesch HR, Gustafson KR, Beutler JA, Boyd MR. A chemical screening strategy for the dereplication and prioritization of HIV-inhibitory aqueous natural products extracts. Journal of Natural Products. 56: 1123-9. PMID 8104236  1
1993 Beutler JA. National Cancer Institute intramural research on human immunodeficiency virus inhibitory and antitumor plant natural products Chapter 15 in: Human Medicinal Agents From Plants. Eds: Kinghorn Ad, Balandrin Mf. DOI: 10.1021/bk-1993-0534.ch015  0.01
1993 Beutler JA, Cardellina JH, Lin CM, Hamel E, Cragg GM, Boyd MR. Centaureidin, a cytotoxic flavone from Polymnia fruticosa, inhibits tubulin polymerization Bioorganic and Medicinal Chemistry Letters. 3: 581-584. DOI: 10.1016/S0960-894X(01)81233-6  1
1993 Beutler JA, McKee TC, Fuller RW, Tischler M, Cardellina JH, Snader KM, McCloud TG, Boyd MR. Frequent occurrence of HIV-inhibitory sulphated polysaccharides in marine invertebrates Antiviral Chemistry and Chemotherapy. 4: 167-172.  1
1992 Beutler JA, Cardellina JH, McMahon JB, Boyd MR, Cragg GM. Anti-HIV and cytotoxic alkaloids from Buchenavia capitata. Journal of Natural Products. 55: 207-13. PMID 1624941  1
1992 Gustafson KR, Cardellina JH, McMahon JB, Gulakowski RJ, Ishitoya J, Szallasi Z, Lewin NE, Blumberg PM, Weislow OS, Beutler JA. A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1. Journal of Medicinal Chemistry. 35: 1978-86. PMID 1597853  1
1992 Lam KS, Titus JA, Dabrah TT, Kimball DL, Veitch JM, Gustavson DR, Compton BJ, Matson JA, Forenza S, Ross J, Miller D, Roach J, Beutler JA. Improved processes for the production and isolation of dynemicin A and large scale fermentation in a 10,000 liter fermentor J Industrial Microbiol. 11: 7-12. PMID 1369016 DOI: 10.1007/BF01583725  1
1992 Chmurny GN, Hilton BD, Brobst S, Look SA, Witherup KM, Beutler JA. 1H- and 13C-nmr assignments for taxol, 7-epi-taxol, and cephalomannine. Journal of Natural Products. 55: 414-23. PMID 1355110  1
1992 Gustafson KR, Cardellina JH II, Manfredi KP, Beutler JA, McMahon JB, Boyd MR. AIDS-antiviral research at the United States National Cancer Institute In: Natural Products as Antiviral Agents, Eds: Chu Ck, Cutler H. 57-67.  1
1991 Schaufelberger DE, McCloud TG, Beutler JA. Laser-light-scattering detection for high-speed counter-current chromatography. Journal of Chromatography. 538: 87-90. PMID 2050798  1
1991 Beutler JA, Chmurny GM, Look SA, Witherup KM. Taxinine M, a new tetracyclic taxane from Taxus brevifolia. Journal of Natural Products. 54: 893-7. PMID 1955887  1
1991 Schaufelberger DE, Koleck MP, Beutler JA, Vatakis AM, Alvarado AB, Andrews P, Marzo LV, Muschik GM, Roach J, Ross JT. The large-scale isolation of bryostatin 1 from Bugula neritina following current good manufacturing practices. Journal of Natural Products. 54: 1265-70. PMID 1800630  1
1991 Schaufelberger DE, Chmurny GN, Beutler JA, Koleck MP, Alvarado AB, Schaufelberger BW, Muschik GM. Revised structure of bryostatin 3 and isolation of the bryostatin 3 26-ketone from Bugula neritina J Org Chem. 56: 2895-2900. DOI: 10.1021/jo00008a054  1
1990 Beutler JA, Chmurny GN, Clark P, Metral CJ, Roman J, Forenza S. Two novel phenolics from Actinomadura verrucosospora. The Journal of Antibiotics. 43: 107-9. PMID 2307621  1
1990 Beutler JA, Alvarado AB, Schaufelberger DE, Andrews P, McCloud TG. Dereplication of phorbol bioactives: Lyngbya majuscula and Croton cuneatus. Journal of Natural Products. 53: 867-74. PMID 2128889  1
1990 Schaufelberger DE, Alvarado AB, Andrews P, Beutler JA. Detection and quantitation of bryostatin 1 and 2 in Bugula neritina by combined high-performance liquid chromatography and 3H-phorbol dibutyrate displacemement J Liq Chromatogr. 13: 583-598. DOI: 10.1080/01483919008051807  1
1989 Beutler JA, Alvarado AB, McCloud TG, Cragg GM. Distribution of phorbol ester bioactivity in the Euphorbiaceae Phytother Res. 3: 188-192. DOI: 10.1002/ptr.2650030507  1
1988 Tempesta MS, Corley DG, Beutler JA, Metral CJ, Yunes RA, Giacomozzi CA, Calixto JB. Phyllanthimide, a new alkaloid from Phyllanthus sellowianus. Journal of Natural Products. 51: 617-8. PMID 3404158  1
1988 Beutler JA, Hilton BD, Clark P, Tempesta MS, Corley DG. Absolute and relative configuration of erythroskyrin. Journal of Natural Products. 51: 562-6. PMID 3404152  1
1987 Allam K, Beutler JA, LeQuesne PW. 14-ketoalstonidine and other alkaloidal constituents of the stem bark of Alstonia constricta J Nat Prod. 50: 623-625. DOI: 10.1021/np50052a007  0.52
1987 Livant PD, Beutler JA. Conformations of the securinine alkaloids as studied by high-field 13C-, 1H- and 2-D nmr, and molecular mechanics calculations Tetrahedron. 43: 2915-2924. DOI: 10.1016/S0040-4020(01)86830-7  1
1987 Beutler JA, Brubaker AN. The chemistry and pharmacology of the securinine alkaloids Drugs Fut. 12: 957-976.  1
1985 Beutler JA, Karbon EW, Brubaker AN, Malik R, Curtis DR, Enna SJ. Securinine alkaloids: a new class of GABA receptor antagonist. Brain Research. 330: 135-40. PMID 2985189 DOI: 10.1016/0006-8993(85)90014-9  1
1985 Beutler JA. GABA receptor as a site for antiepileptic drug action In: L.E.R.S. Monograph Series, Ed: Bartholini G. 3: 195-201.  0.01
1984 Beutler JA, Livant PD. CMR assignments of the securinine alkaloids J Nat Prod. 47: 677-681. DOI: 10.1021/np50034a018  1
1981 Chirieleison R, Beutler JA. Mushroom poisoning in Berks County Pennsylvania Med. 84: 65-66. PMID 7243296  0.01
1981 Beutler JA, Der Marderosian AH. Chemical variation in Amanita J Nat Prod. 44: 422-431. DOI: 10.1021/np50016a005  1
1980 Beutler JA, Vergeer PP. Amatoxins in American mushrooms: Evaluation of the Meixner test Mycologia. 72: 1142-1149. DOI: 10.2307/3759568  0.01
1979 Beutler JA, Varano A, DerMarderosian A. Pyrolysis analysis of the herbicide paraquat on cannabis by coupled gas chromatography-infrared spectroscopy. Journal of Forensic Sciences. 24: 808-13. PMID 541644  0.12
1978 Beutler JA, Der Marderosian AH. Chemotaxonomy of Cannabis I. Crossbreeding between Cannabis sativa and C. ruderalis, with analysis of cannabinoid content Econ Bot. 32: 387-394. DOI: 10.1007/BF02907934  1
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