Yongchao Su, Ph.D. - Publications

2011 Chemistry Iowa State University, Ames, IA, United States 
solid-state NMR spectroscopy to investigate the structure and dynamics of membrane proteins and fibrous proteins

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li M, Lu X, Xu W, Troup GM, McNevin MJ, Nie H, Su Y. Quantifying Pharmaceutical Formulations from Proton Detected Solid-State NMR under Ultrafast Magic Angle Spinning. Journal of Pharmaceutical Sciences. PMID 32679211 DOI: 10.1016/j.xphs.2020.06.026  1
2020 Zhao F, Zhang D, Zhou Q, Zhao F, He M, Yang Z, Su Y, Zhai Y, Yan J, Zhang G, Xue A, Tang J, Han X, Shi Y, Zhu Y, et al. Scleral HIF-1α is a prominent regulatory candidate for genetic and environmental interactions in human myopia pathogenesis. Ebiomedicine. 57: 102878. PMID 32652319 DOI: 10.1016/j.ebiom.2020.102878  1
2020 Sahakijpijarn S, Moon C, Ma X, Su Y, Koleng JJ, Dolocan A, Williams Iii RO. Using thin film freezing to minimize excipients in inhalable tacrolimus dry powder formulations. International Journal of Pharmaceutics. 119490. PMID 32603840 DOI: 10.1016/j.ijpharm.2020.119490  1
2020 Skomski D, Liu Z, Su Y, John CT, Doty A, Forster SP, Teller R, Barrett SE, Xu W. An Imaging Toolkit for Physical Characterization of Long-Acting Pharmaceutical Implants. Journal of Pharmaceutical Sciences. PMID 32534030 DOI: 10.1016/j.xphs.2020.05.031  1
2020 Skomski D, Varsolona RJ, Su Y, Zhang J, Teller R, Forster SP, Barrett SE, Xu W. Islatravir Case Study for Enhanced Screening of Thermodynamically Stable Crystalline Anhydrate Phases in Pharmaceutical Process Development by Hot Melt Extrusion. Molecular Pharmaceutics. PMID 32511923 DOI: 10.1021/acs.molpharmaceut.0c00316  1
2020 Lu X, Tsutsumi Y, Huang C, Xu W, Byrn SR, Templeton AC, Buevich AV, Amoureux JP, Su Y. Molecular packing of pharmaceuticals analyzed with paramagnetic relaxation enhancement and ultrafast magic angle pinning NMR. Physical Chemistry Chemical Physics : Pccp. PMID 32495810 DOI: 10.1039/d0cp02049d  1
2020 Yang F, Su Y, Small J, Huang C, Martin GE, Farrington AM, DiNunzio J, Brown CD. Probing the Molecular-Level Interactions in an Active Pharmaceutical Ingredient (API) - Polymer Dispersion and the Resulting Impact on Drug Product Formulation. Pharmaceutical Research. 37: 94. PMID 32405662 DOI: 10.1007/s11095-020-02813-z  1
2020 Lu X, Li M, Huang C, Lowinger MB, Xu W, Yu L, Byrn SR, Templeton AC, Su Y. Atomic-level Drug Substance and Polymer Interaction in Posaconazole Amorphous Solid Dispersion from Solid-State NMR. Molecular Pharmaceutics. PMID 32401529 DOI: 10.1021/acs.molpharmaceut.0c00268  1
2020 Lu X, Huang C, Li M, Skomski D, Xu W, Yu L, Byrn SR, Templeton AC, Su Y. Molecular Mechanism of Crystalline-to-Amorphous Conversion of Pharmaceutical Solids from F Magic Angle Spinning NMR. The Journal of Physical Chemistry. B. PMID 32378905 DOI: 10.1021/acs.jpcb.0c02131  1
2020 Su Y, Chen Y, Tian Z, Lu C, Chen L, Ma X. lncRNAs classifier to accurately predict the recurrence of thymic epithelial tumors. Thoracic Cancer. PMID 32374079 DOI: 10.1111/1759-7714.13439  1
2019 Yin J, Huang C, Guan H, Pang Z, Su Y, Kong X. In-situ Solid-state NMR Characterization of Pharmaceutical Materials: An Example of Drug-Polymer Thermal Mixing. Magnetic Resonance in Chemistry : Mrc. PMID 31846098 DOI: 10.1002/mrc.4982  1
2019 Gelenter MD, Smith KJ, Liao SY, Mandala VS, Dregni AJ, Lamm MS, Tian Y, Xu W, Pochan DJ, Tucker TJ, Su Y, Hong M. The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations. Nature Structural & Molecular Biology. PMID 31235909 DOI: 10.1038/s41594-019-0238-6  1
2019 Lu X, Huang C, Lowinger MB, Yang F, Xu W, Brown CD, Hesk D, Koynov A, Schenck L, Su Y. Molecular Interactions in Posaconazole Amorphous Solid Dispersions from Two-Dimensional Solid-State NMR Spectroscopy. Molecular Pharmaceutics. PMID 31021639 DOI: 10.1021/acs.molpharmaceut.9b00174  1
2019 Figueroa B, Nguyen T, Sotthivirat M, Xu W, Rhodes TA, Lamm MS, Smith RL, John CT, Su Y, Fu D. Detecting and Quantifying Microscale Chemical Reactions in Pharmaceutical Tablets by Stimulated Raman Scattering Microscopy. Analytical Chemistry. PMID 31009215 DOI: 10.1021/acs.analchem.9b01269  1
2019 Lu X, Skomski D, Thompson KC, McNevin MJ, Xu W, Su Y. Three-Dimensional NMR Spectroscopy of Fluorinated Pharmaceutical Solids under Ultrafast Magic Angle Spinning. Analytical Chemistry. PMID 30990668 DOI: 10.1021/acs.analchem.9b00884  1
2019 Ma X, Huang S, Lowinger MB, Liu X, Lu X, Su Y, Williams RO. Influence of Mechanical and Thermal Energy on Nifedipine Amorphous Solid Dispersions Prepared by Hot Melt Extrusion: Preparation and Physical Stability. International Journal of Pharmaceutics. PMID 30858115 DOI: 10.1016/j.ijpharm.2019.03.014  1
2018 Huang C, Klinzing G, Procopio A, Yang F, Ren J, Burlage R, Zhu L, Su Y. Understanding Compression Induced Amorphization of Crystalline Posaconazole. Molecular Pharmaceutics. PMID 30575400 DOI: 10.1021/acs.molpharmaceut.8b01122  1
2018 Lu X, Xu W, Hanada M, Jermain SV, Williams RO, Su Y. Solid-state NMR analysis of crystalline and amorphous Indomethacin: An experimental protocol for full resonance assignments. Journal of Pharmaceutical and Biomedical Analysis. 165: 47-55. PMID 30503894 DOI: 10.1016/j.jpba.2018.11.001  1
2018 Iadanza MG, Silvers R, Boardman J, Smith HI, Karamanos TK, Debelouchina GT, Su Y, Griffin RG, Ranson NA, Radford SE. The structure of a β-microglobulin fibril suggests a molecular basis for its amyloid polymorphism. Nature Communications. 9: 4517. PMID 30375379 DOI: 10.1038/s41467-018-06761-6  1
2018 Francis A, Nguyen TT, Lamm MS, Teller R, Forster S, Xu W, Rhodes TA, Smith R, Kuiper J, Su Y, Fu D. In-Situ Stimulated Raman Scattering (SRS) Microscopy Study of the Dissolution of Sustained-Release Implant Formulation. Molecular Pharmaceutics. PMID 30362772 DOI: 10.1021/acs.molpharmaceut.8b00965  1
2018 Hirsh DA, Su Y, Nie H, Xu W, Stueber D, Variankaval N, Schurko RW. Quantifying Disproportionation in Pharmaceutical Formulations with Cl Solid-State NMR. Molecular Pharmaceutics. PMID 30016112 DOI: 10.1021/acs.molpharmaceut.8b00470  1
2017 Correa-Soto C, Trasi NS, Schmitt PD, Su Y, Liu Z, Miller E, Variankaval N, Marsac PJ, Simpson GJ, Taylor LS. Second harmonic generation microscopy as a tool for the early detection of crystallization in spray dried dispersions. Journal of Pharmaceutical and Biomedical Analysis. 146: 86-95. PMID 28866472 DOI: 10.1016/j.jpba.2017.07.066  1
2017 Ni QZ, Yang F, Can TV, Sergeyev IV, D'Addio SM, Jawla SK, Li Y, Lipert MP, Xu W, Williamson RT, Leone A, Griffin RG, Su Y. In-Situ Characterization of Pharmaceutical Formulations by Dynamic Nuclear Polarization Enhanced MAS NMR. The Journal of Physical Chemistry. B. PMID 28762740 DOI: 10.1021/acs.jpcb.7b07213  1
2017 Purohit HS, Ormes JD, Saboo S, Su Y, Lamm MS, Mann AKP, Taylor LS. Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy. Pharmaceutical Research. PMID 28455777 DOI: 10.1007/s11095-017-2145-z  1
2017 Ni QZ, Markhasin E, Can TV, Corzilius B, Tan KO, Barnes AB, Daviso E, Su Y, Herzfeld J, Griffin RG. Peptide and Protein Dynamics and Low-Temperature/DNP Magic Angle Spinning NMR. The Journal of Physical Chemistry. B. PMID 28437077 DOI: 10.1021/acs.jpcb.7b02066  1
2016 Zhou L, Li S, Qi G, Su Y, Li J, Zheng A, Yi X, Wang Q, Deng F. Methanol carbonylation over copper-modified mordenite zeolite: A solid-state NMR study. Solid State Nuclear Magnetic Resonance. 80: 1-6. PMID 27770652 DOI: 10.1016/j.ssnmr.2016.10.003  1
2016 Nie H, Su Y, Zhang M, Song Y, Leone A, Taylor LS, Marsac PJ, Li T, Byrn SR. Solid-State Spectroscopic Investigation of Molecular Interactions between Clofazimine and Hypromellose Phthalate in Amorphous Solid Dispersions. Molecular Pharmaceutics. PMID 27653759 DOI: 10.1021/acs.molpharmaceut.6b00740  1
2016 Yang F, Su Y, Zhang J, DiNunzio J, Leone A, Huang C, Brown CD. Rheology guided rational selection of processing temperature to prepare copovidone/nifedipine amorphous solid dispersions via hot melt extrusion (HME). Molecular Pharmaceutics. PMID 27602878 DOI: 10.1021/acs.molpharmaceut.6b00516  1
2016 Yang F, Su Y, Zhu L, Brown CD, Rosen LA, Rosenberg KJ. Rheological and solid-state NMR assessments of copovidone/clotrimazole model solid dispersions. International Journal of Pharmaceutics. PMID 26780122 DOI: 10.1016/j.ijpharm.2016.01.026  1
2016 Zhang J, Ouyang Q, Guo Q, Li Z, Fan G, Su Y, Jiang L, Lavernia EJ, Schoenung JM, Zhang D. 3D Microstructure-based finite element modeling of deformation and fracture of SiCp/Al composites Composites Science and Technology. 123: 1-9. DOI: 10.1016/j.compscitech.2015.11.014  1
2015 Su Y, Zhang Z, Zhang Q, Zhang Y, Liu Z. Analgesic efficacy of bilateral superficial and deep cervical plexus block in patients with secondary hyperparathyroidism due to chronic renal failure. Annals of Surgical Treatment and Research. 89: 325-329. PMID 26665128 DOI: 10.4174/astr.2015.89.6.325  1
2015 Colvin MT, Silvers R, Frohm B, Su Y, Linse S, Griffin RG. High Resolution Structural Characterization of Aβ42 Amyloid Fibrils by Magic Angle Spinning NMR. Journal of the American Chemical Society. 137: 7509-18. PMID 26001057 DOI: 10.1021/jacs.5b03997  1
2015 Su Y, Andreas L, Griffin RG. Magic angle spinning NMR of proteins: high-frequency dynamic nuclear polarization and (1)h detection. Annual Review of Biochemistry. 84: 465-97. PMID 25839340 DOI: 10.1146/annurev-biochem-060614-034206  1
2015 Eddy MT, Su Y, Silvers R, Andreas L, Clark L, Wagner G, Pintacuda G, Emsley L, Griffin RG. Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR. Journal of Biomolecular Nmr. 61: 299-310. PMID 25634301 DOI: 10.1007/s10858-015-9903-1  1
2015 Zhou L, Li S, Su Y, Li B, Deng F. Paramagnetic relaxation enhancement solid-state NMR studies of heterogeneous catalytic reaction over HY zeolite using natural abundance reactant. Solid State Nuclear Magnetic Resonance. 66: 29-32. PMID 25616847 DOI: 10.1016/j.ssnmr.2014.12.008  1
2015 Eddy MT, Andreas L, Teijido O, Su Y, Clark L, Noskov SY, Wagner G, Rostovtseva TK, Griffin RG. Magic angle spinning nuclear magnetic resonance characterization of voltage-dependent anion channel gating in two-dimensional lipid crystalline bilayers. Biochemistry. 54: 994-1005. PMID 25545271 DOI: 10.1021/bi501260r  1
2015 Wang N, Zhao LC, Zheng YQ, Dong MJ, Su Y, Chen WJ, Hu ZL, Yang YJ, Gao HC. Alteration of interaction between astrocytes and neurons in different stages of diabetes: a nuclear magnetic resonance study using [1-(13)C]glucose and [2-(13)C]acetate. Molecular Neurobiology. 51: 843-52. PMID 25048983 DOI: 10.1007/s12035-014-8808-4  0.01
2014 Su Y, Sarell CJ, Eddy MT, Debelouchina GT, Andreas LB, Pashley CL, Radford SE, Griffin RG. Secondary structure in the core of amyloid fibrils formed from human β₂m and its truncated variant ΔN6. Journal of the American Chemical Society. 136: 6313-25. PMID 24679070 DOI: 10.1021/ja4126092  1
2013 Hu W, Su Y, Zhou L, Pang A, Cai R, Ma X, Li S. Molecular dynamics of neutral polymer bonding agent (NPBA) as revealed by solid-state NMR spectroscopy. Molecules (Basel, Switzerland). 19: 1353-66. PMID 24451254 DOI: 10.3390/molecules19011353  1
2013 Zhou L, Li S, Su Y, Yi X, Zheng A, Deng F. Interaction between histidine and Zn(II) metal ions over a wide pH as revealed by solid-state NMR spectroscopy and DFT calculations. The Journal of Physical Chemistry. B. 117: 8954-65. PMID 23841698 DOI: 10.1021/jp4041937  1
2013 Li S, Zhou L, Su Y, Han B, Deng F. 13C and 15N spectral editing inside histidine imidazole ring through solid-state NMR spectroscopy. Solid State Nuclear Magnetic Resonance. 54: 13-7. PMID 23731549 DOI: 10.1016/j.ssnmr.2013.05.002  1
2013 Markhasin E, Hu J, Su Y, Herzfeld J, Griffin RG. Efficient, balanced, transmission line RF circuits by back propagation of common impedance nodes. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 231: 32-8. PMID 23567880 DOI: 10.1016/j.jmr.2013.02.017  1
2013 Sarell CJ, Woods LA, Su Y, Debelouchina GT, Ashcroft AE, Griffin RG, Stockley PG, Radford SE. Expanding the repertoire of amyloid polymorphs by co-polymerization of related protein precursors. The Journal of Biological Chemistry. 288: 7327-37. PMID 23329840 DOI: 10.1074/jbc.M112.447524  1
2013 Su Y, Li S, Hong M. Cationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMR. Amino Acids. 44: 821-33. PMID 23108593 DOI: 10.1007/s00726-012-1421-9  1
2012 Li S, Su Y, Hong M. Intramolecular 1H-13C distance measurement in uniformly 13C, 15N labeled peptides by solid-state NMR. Solid State Nuclear Magnetic Resonance. 45: 51-8. PMID 22749432 DOI: 10.1016/j.ssnmr.2012.06.001  1
2012 Su Y, Hu F, Hong M. Paramagnetic Cu(II) for probing membrane protein structure and function: inhibition mechanism of the influenza M2 proton channel. Journal of the American Chemical Society. 134: 8693-702. PMID 22519936 DOI: 10.1021/ja3026328  1
2011 Su Y, Hong M. Conformational disorder of membrane peptides investigated from solid-state NMR line widths and line shapes. The Journal of Physical Chemistry. B. 115: 10758-67. PMID 21806038 DOI: 10.1021/jp205002n  1
2011 Hong M, Su Y. Structure and dynamics of cationic membrane peptides and proteins: insights from solid-state NMR. Protein Science : a Publication of the Protein Society. 20: 641-55. PMID 21344534 DOI: 10.1002/pro.600  1
2011 Su Y, Waring AJ, Ruchala P, Hong M. Structures of β-hairpin antimicrobial protegrin peptides in lipopolysaccharide membranes: mechanism of gram selectivity obtained from solid-state nuclear magnetic resonance. Biochemistry. 50: 2072-83. PMID 21302955 DOI: 10.1021/bi101975v  1
2010 Doherty T, Su Y, Hong M. High-resolution orientation and depth of insertion of the voltage-sensing S4 helix of a potassium channel in lipid bilayers. Journal of Molecular Biology. 401: 642-52. PMID 20600109 DOI: 10.1016/j.jmb.2010.06.048  1
2010 Su Y, Waring AJ, Ruchala P, Hong M. Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR. Biochemistry. 49: 6009-20. PMID 20550193 DOI: 10.1021/bi100642n  1
2010 Su Y, DeGrado WF, Hong M. Orientation, dynamics, and lipid interaction of an antimicrobial arylamide investigated by 19F and 31P solid-state NMR spectroscopy. Journal of the American Chemical Society. 132: 9197-205. PMID 20536141 DOI: 10.1021/ja103658h  1
2010 Li S, Zheng A, Su Y, Fang H, Shen W, Yu Z, Chen L, Deng F. Extra-framework aluminium species in hydrated faujasite zeolite as investigated by two-dimensional solid-state NMR spectroscopy and theoretical calculations. Physical Chemistry Chemical Physics : Pccp. 12: 3895-903. PMID 20358084 DOI: 10.1039/b915401a  1
2010 Li S, Su Y, Luo W, Hong M. Water-protein interactions of an arginine-rich membrane peptide in lipid bilayers investigated by solid-state nuclear magnetic resonance spectroscopy. The Journal of Physical Chemistry. B. 114: 4063-9. PMID 20199036 DOI: 10.1021/jp912283r  1
2009 Su Y, Doherty T, Waring AJ, Ruchala P, Hong M. Roles of arginine and lysine residues in the translocation of a cell-penetrating peptide from (13)C, (31)P, and (19)F solid-state NMR. Biochemistry. 48: 4587-95. PMID 19364134 DOI: 10.1021/bi900080d  1
2008 Su Y, Mani R, Doherty T, Waring AJ, Hong M. Reversible sheet-turn conformational change of a cell-penetrating peptide in lipid bilayers studied by solid-state NMR. Journal of Molecular Biology. 381: 1133-44. PMID 18656895 DOI: 10.1016/j.jmb.2008.06.007  1
2008 Su Y, Mani R, Hong M. Asymmetric insertion of membrane proteins in lipid bilayers by solid-state NMR paramagnetic relaxation enhancement: a cell-penetrating Peptide example. Journal of the American Chemical Society. 130: 8856-64. PMID 18597439 DOI: 10.1021/ja802383t  1
2007 Li S, Zheng A, Su Y, Zhang H, Chen L, Yang J, Ye C, Deng F. Brønsted/Lewis acid synergy in dealuminated HY zeolite: a combined solid-state NMR and theoretical calculation study. Journal of the American Chemical Society. 129: 11161-71. PMID 17705381 DOI: 10.1021/ja072767y  1
2006 Xu J, Zheng A, Yang J, Su Y, Wang J, Zeng D, Zhang M, Ye C, Deng F. Acidity of mesoporous MoO(x)/ZrO2 and WO(x)/ZrO2 materials: a combined solid-state NMR and theoretical calculation study. The Journal of Physical Chemistry. B. 110: 10662-71. PMID 16771312 DOI: 10.1021/jp0614087  1
2006 Wang J, Su Y, Xu J, Ye C, Deng F. Acid sites and oxidation center in molybdena supported on tin oxide as studied by solid-state NMR spectroscopy and theoretical calculation. Physical Chemistry Chemical Physics : Pccp. 8: 2378-84. PMID 16710485 DOI: 10.1039/b516833c  1
2005 Zheng A, Chen L, Yang J, Zhang M, Su Y, Yue Y, Ye C, Deng F. Combined DFT theoretical calculation and solid-state NMR studies of Al substitution and acid sites in zeolite MCM-22. The Journal of Physical Chemistry. B. 109: 24273-9. PMID 16375424 DOI: 10.1021/jp0527249  1
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